Danio rerio

44 known processes

dlx5a

distal-less homeobox gene 5a

(Aliases: dlx4,zgc:101787,MGC101787)

dlx5a biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
organic substance biosynthetic process GO:1901576 289 0.998
Human Mouse
response to abiotic stimulus GO:0009628 122 0.997
auditory receptor cell fate specification GO:0042667 2 0.997
Zebrafish
organic cyclic compound metabolic process GO:1901360 301 0.996
Human Mouse
regionalization GO:0003002 274 0.995
response to external stimulus GO:0009605 264 0.988
regulation of biosynthetic process GO:0009889 250 0.985
Human Mouse
biosynthetic process GO:0009058 294 0.985
Human Mouse
cellular macromolecule metabolic process GO:0044260 391 0.981
Human Mouse
regulation of transcription involved in cell fate commitment GO:0060850 1 0.981
cellular aromatic compound metabolic process GO:0006725 295 0.980
Human Mouse
nitrogen compound metabolic process GO:0006807 319 0.979
Human Mouse
positive regulation of cellular biosynthetic process GO:0031328 68 0.973
Human Mouse
cell morphogenesis involved in differentiation GO:0000904 195 0.967
Mouse
central nervous system development GO:0007417 387 0.964
specification of organ identity GO:0010092 2 0.961
nucleobase containing compound biosynthetic process GO:0034654 205 0.961
Human Mouse
cellular nitrogen compound metabolic process GO:0034641 290 0.960
Human Mouse
sensory organ morphogenesis GO:0090596 200 0.960
Zebrafish Mouse
embryonic organ development GO:0048568 381 0.958
Zebrafish Mouse
regulation of cellular biosynthetic process GO:0031326 245 0.954
Human Mouse
heterocycle biosynthetic process GO:0018130 215 0.954
Human Mouse
inner ear receptor cell fate commitment GO:0060120 4 0.950
Zebrafish
aromatic compound biosynthetic process GO:0019438 217 0.950
Human Mouse
positive regulation of nucleic acid templated transcription GO:1903508 57 0.945
Human Mouse
regulation of transcription dna templated GO:0006355 213 0.939
Human Mouse
positive regulation of gene expression GO:0010628 71 0.932
Human Mouse
regulation of gene expression GO:0010468 265 0.932
Human Mouse
skeletal system development GO:0001501 181 0.923
positive regulation of stem cell proliferation GO:2000648 1 0.922
positive regulation of metabolic process GO:0009893 108 0.920
Human Mouse
inner ear development GO:0048839 126 0.920
Zebrafish Mouse
generation of neurons GO:0048699 385 0.918
Zebrafish Mouse
macromolecule biosynthetic process GO:0009059 227 0.918
Human Mouse
mesenchymal cell proliferation GO:0010463 1 0.915
regulation of nucleic acid templated transcription GO:1903506 213 0.914
Human Mouse
regulation of multicellular organismal process GO:0051239 277 0.913
Rat
auditory receptor cell fate commitment GO:0009912 4 0.911
Zebrafish
morphogenesis of an epithelium GO:0002009 333 0.909
neuron differentiation GO:0030182 353 0.906
Zebrafish Mouse
regulation of rna metabolic process GO:0051252 224 0.906
Human Mouse
regulation of wound healing GO:0061041 2 0.904
cellular nitrogen compound biosynthetic process GO:0044271 218 0.902
Human Mouse
response to mechanical stimulus GO:0009612 24 0.901
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.900
Human Mouse
cellular macromolecule biosynthetic process GO:0034645 224 0.900
Human Mouse
ear development GO:0043583 127 0.899
Zebrafish Mouse
inner ear morphogenesis GO:0042472 63 0.893
Zebrafish Mouse
otic vesicle development GO:0071599 42 0.891
Zebrafish
embryonic limb morphogenesis GO:0030326 2 0.889
Mouse
stem cell proliferation GO:0072089 4 0.878
mechanoreceptor differentiation GO:0042490 37 0.876
Zebrafish
response to chemical GO:0042221 320 0.875
Mouse
regulation of metabolic process GO:0019222 359 0.873
Human Mouse
neuron projection guidance GO:0097485 86 0.870
Mouse
cell surface receptor signaling pathway GO:0007166 325 0.849
Mouse
positive regulation of biological process GO:0048518 253 0.833
Human Mouse Rat
nucleobase containing compound metabolic process GO:0006139 274 0.832
Human Mouse
negative regulation of biological process GO:0048519 304 0.828
regulation of mesenchymal cell proliferation GO:0010464 1 0.828
inner ear receptor cell differentiation GO:0060113 29 0.823
Zebrafish
nucleic acid templated transcription GO:0097659 181 0.821
Human Mouse
axon guidance GO:0007411 86 0.816
Mouse
negative regulation of multicellular organismal process GO:0051241 69 0.814
negative regulation of transcription from rna polymerase ii promoter GO:0000122 16 0.806
limb bud formation GO:0060174 2 0.802
forebrain neuron fate commitment GO:0021877 1 0.799
brain development GO:0007420 293 0.793
medial fin morphogenesis GO:0035141 14 0.789
neuron fate specification GO:0048665 20 0.787
Zebrafish
regulation of nitrogen compound metabolic process GO:0051171 251 0.780
Human Mouse
appendage morphogenesis GO:0035107 56 0.775
positive regulation of cellular process GO:0048522 201 0.773
Human Mouse Rat
regulation of rna biosynthetic process GO:2001141 213 0.765
Human Mouse
embryonic organ morphogenesis GO:0048562 274 0.763
Zebrafish Mouse
odontogenesis of dentin containing tooth GO:0042475 1 0.763
cellular biosynthetic process GO:0044249 286 0.762
Human Mouse
hair cell differentiation GO:0035315 32 0.762
Zebrafish
regulation of stem cell proliferation GO:0072091 2 0.762
neuron projection development GO:0031175 180 0.757
Mouse
organic cyclic compound biosynthetic process GO:1901362 223 0.756
Human Mouse
camera type eye morphogenesis GO:0048593 108 0.730
heterocycle metabolic process GO:0046483 290 0.728
Human Mouse
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.709
Human Mouse
rna metabolic process GO:0016070 219 0.707
Human Mouse
forebrain neuron development GO:0021884 7 0.704
regulation of cellular metabolic process GO:0031323 320 0.701
Human Mouse
cell fate commitment GO:0045165 99 0.698
Zebrafish
cell fate specification GO:0001708 68 0.697
Zebrafish
neuron development GO:0048666 262 0.695
Zebrafish Mouse
positive regulation of nucleobase containing compound metabolic process GO:0045935 69 0.689
Human Mouse
positive regulation of macromolecule metabolic process GO:0010604 93 0.685
Human Mouse
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.679
Human Mouse
organ formation GO:0048645 17 0.673
blood vessel morphogenesis GO:0048514 216 0.665
blood vessel development GO:0001568 246 0.665
glial cell migration GO:0008347 3 0.663
neuron fate commitment GO:0048663 26 0.661
Zebrafish
embryonic skeletal system development GO:0048706 97 0.658
medial fin development GO:0033338 16 0.655
forebrain generation of neurons GO:0021872 14 0.653
head development GO:0060322 303 0.650
Mouse
gene expression GO:0010467 252 0.648
Human Mouse
skin development GO:0043588 54 0.647
Zebrafish
regulation of macromolecule biosynthetic process GO:0010556 225 0.638
Human Mouse
endothelial cell proliferation GO:0001935 11 0.626
regulation of primary metabolic process GO:0080090 311 0.625
Human Mouse
neuron projection morphogenesis GO:0048812 161 0.618
Mouse
determination of ventral identity GO:0048264 21 0.612
skeletal system morphogenesis GO:0048705 102 0.607
Mouse
appendage development GO:0048736 80 0.602
dorsal ventral pattern formation GO:0009953 125 0.597
glucocorticoid metabolic process GO:0008211 2 0.594
negative regulation of transcription dna templated GO:0045892 45 0.573
cellular response to organic substance GO:0071310 105 0.565
Mouse
regulation of biological quality GO:0065008 263 0.559
apoptotic process GO:0006915 116 0.558
axonogenesis GO:0007409 152 0.550
Mouse
otic vesicle morphogenesis GO:0071600 34 0.545
Zebrafish
cell proliferation GO:0008283 80 0.541
Human Mouse
positive regulation of nervous system development GO:0051962 25 0.541
regulation of chondrocyte differentiation GO:0032330 1 0.536
cranial suture morphogenesis GO:0060363 1 0.526
fin morphogenesis GO:0033334 53 0.525
limb development GO:0060173 8 0.523
Mouse
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.522
Mouse
regulation of cell proliferation GO:0042127 37 0.521
Mouse
olfactory placode morphogenesis GO:0071699 7 0.515
regulation of endothelial cell proliferation GO:0001936 1 0.509
epithelial cell differentiation GO:0030855 116 0.509
Zebrafish Mouse
gliogenesis GO:0042063 45 0.504
forebrain development GO:0030900 96 0.499
cartilage development GO:0051216 96 0.496
hematopoietic or lymphoid organ development GO:0048534 191 0.496
vasculature development GO:0001944 278 0.484
negative regulation of macromolecule metabolic process GO:0010605 76 0.481
proximal distal pattern formation GO:0009954 1 0.478
chondrocyte development GO:0002063 4 0.473
negative regulation of signal transduction in absence of ligand GO:1901099 1 0.468
nucleic acid metabolic process GO:0090304 244 0.467
Human Mouse
negative regulation of macromolecule biosynthetic process GO:0010558 48 0.463
gland development GO:0048732 143 0.462
stem cell maintenance GO:0019827 4 0.462
transcription dna templated GO:0006351 181 0.460
Human Mouse
negative regulation of biosynthetic process GO:0009890 55 0.459
positive regulation of biosynthetic process GO:0009891 68 0.458
Human Mouse
positive regulation of mesenchymal cell proliferation GO:0002053 1 0.452
rna biosynthetic process GO:0032774 181 0.442
Human Mouse
regulation of developmental process GO:0050793 247 0.441
Rat
protein import GO:0017038 3 0.435
positive regulation of neurogenesis GO:0050769 24 0.433
homeostatic process GO:0042592 142 0.427
embryonic cranial skeleton morphogenesis GO:0048701 90 0.424
morphogenesis of a branching structure GO:0001763 21 0.423
cellular component morphogenesis GO:0032989 336 0.421
Mouse
epithelial cell migration GO:0010631 25 0.420
fibroblast growth factor receptor signaling pathway GO:0008543 22 0.416
signal transduction GO:0007165 455 0.411
Mouse
notochord development GO:0030903 54 0.407
regulation of epithelial cell proliferation GO:0050678 3 0.396
Mouse
ear morphogenesis GO:0042471 64 0.393
Zebrafish Mouse
determination of dorsal ventral asymmetry GO:0048262 34 0.391
digestive tract development GO:0048565 265 0.385
cell part morphogenesis GO:0032990 246 0.383
Mouse
regulation of macromolecule metabolic process GO:0060255 317 0.381
Human Mouse
regulation of neurogenesis GO:0050767 87 0.373
negative regulation of nucleic acid templated transcription GO:1903507 45 0.372
negative regulation of gene expression GO:0010629 65 0.371
negative regulation of embryonic development GO:0045992 11 0.364
posterior lateral line neuromast primordium migration GO:0048920 12 0.360
positive regulation of cell proliferation GO:0008284 15 0.357
Mouse
neural nucleus development GO:0048857 15 0.348
regulation of signal transduction GO:0009966 225 0.347
Mouse
negative regulation of cellular biosynthetic process GO:0031327 55 0.346
axon development GO:0061564 166 0.333
Mouse
angiogenesis GO:0001525 158 0.332
system process GO:0003008 185 0.323
cell migration GO:0016477 237 0.320
catecholamine biosynthetic process GO:0042423 2 0.319
negative regulation of cellular metabolic process GO:0031324 77 0.318
connective tissue development GO:0061448 99 0.312
small molecule metabolic process GO:0044281 77 0.312
extrinsic apoptotic signaling pathway in absence of ligand GO:0097192 1 0.310
regulation of multicellular organismal development GO:2000026 223 0.306
morphogenesis of an epithelial fold GO:0060571 1 0.304
death GO:0016265 121 0.299
embryonic appendage morphogenesis GO:0035113 30 0.298
Mouse
regulation of transcription from rna polymerase ii promoter GO:0006357 114 0.292
Mouse
neuron death GO:0070997 21 0.291
otic vesicle formation GO:0030916 27 0.290
Zebrafish
heart looping GO:0001947 94 0.288
regulation of myotube differentiation GO:0010830 2 0.283
heart formation GO:0060914 13 0.281
limb morphogenesis GO:0035108 7 0.278
Mouse
negative regulation of muscle tissue development GO:1901862 2 0.275
behavior GO:0007610 74 0.270
positive regulation of programmed cell death GO:0043068 29 0.267
oligodendrocyte differentiation GO:0048709 23 0.262
response to stress GO:0006950 263 0.258
transcription from rna polymerase ii promoter GO:0006366 80 0.253
Mouse
renal system development GO:0072001 94 0.252
bmp signaling pathway GO:0030509 52 0.251
Mouse
negative regulation of nucleobase containing compound metabolic process GO:0045934 59 0.250
cellular component movement GO:0006928 335 0.246
Mouse
pectoral fin development GO:0033339 50 0.245
chordate embryonic development GO:0043009 271 0.240
developmental growth GO:0048589 166 0.240
olfactory bulb development GO:0021772 4 0.238
negative regulation of striated muscle tissue development GO:0045843 2 0.236
immune system process GO:0002376 241 0.236
negative regulation of developmental process GO:0051093 65 0.229
skeletal muscle tissue development GO:0007519 67 0.228
positive regulation of response to stimulus GO:0048584 80 0.227
Mouse
adenohypophysis development GO:0021984 15 0.222
cellular ketone metabolic process GO:0042180 11 0.219
positive regulation of rna metabolic process GO:0051254 59 0.215
Human Mouse
camera type eye development GO:0043010 222 0.214
Zebrafish
specification of symmetry GO:0009799 204 0.212
positive regulation of transcription from rna polymerase ii promoter GO:0045944 22 0.207
Mouse
neuron fate determination GO:0048664 2 0.205
cellular response to chemical stimulus GO:0070887 157 0.204
Mouse
determination of bilateral symmetry GO:0009855 204 0.204
telencephalon development GO:0021537 14 0.203
eye morphogenesis GO:0048592 144 0.201
tissue remodeling GO:0048771 4 0.196
negative regulation of extrinsic apoptotic signaling pathway in absence of ligand GO:2001240 1 0.191
positive regulation of apoptotic process GO:0043065 29 0.190
trigeminal nerve development GO:0021559 3 0.190
Zebrafish
regulation of cell development GO:0060284 100 0.188
positive regulation of macromolecule biosynthetic process GO:0010557 59 0.187
Human Mouse
glial cell fate specification GO:0021780 4 0.187
cell maturation GO:0048469 23 0.184
cellular response to endogenous stimulus GO:0071495 68 0.182
Mouse
stem cell differentiation GO:0048863 117 0.181
negative regulation of programmed cell death GO:0043069 58 0.177
response to immobilization stress GO:0035902 1 0.175
negative regulation of metabolic process GO:0009892 86 0.171
digestive system development GO:0055123 289 0.168
positive regulation of cellular component biogenesis GO:0044089 3 0.167
cellular response to steroid hormone stimulus GO:0071383 31 0.167
positive regulation of neuron differentiation GO:0045666 12 0.166
posterior lateral line development GO:0048916 38 0.166
protein import into nucleus GO:0006606 3 0.166
regulation of nervous system development GO:0051960 90 0.163
regulation of cellular response to growth factor stimulus GO:0090287 35 0.159
negative regulation of rna metabolic process GO:0051253 48 0.158
response to oxygen levels GO:0070482 25 0.157
embryonic camera type eye development GO:0031076 29 0.155
neuron apoptotic process GO:0051402 20 0.155
positive regulation of cellular metabolic process GO:0031325 94 0.153
Human Mouse
skeletal muscle organ development GO:0060538 78 0.153
positive regulation of signaling GO:0023056 56 0.153
Mouse
cartilage condensation GO:0001502 3 0.149
regulation of signaling GO:0023051 235 0.149
Mouse
positive regulation of transcription dna templated GO:0045893 57 0.147
Human Mouse
regulation of binding GO:0051098 3 0.147
positive regulation of cell motility GO:2000147 11 0.147
muscle structure development GO:0061061 196 0.146
positive regulation of developmental process GO:0051094 50 0.146
Rat
phenol containing compound biosynthetic process GO:0046189 4 0.146
single organism metabolic process GO:0044710 217 0.144
regulation of cell death GO:0010941 103 0.143
cellular response to fibroblast growth factor stimulus GO:0044344 22 0.143
response to organic substance GO:0010033 153 0.142
Mouse
collagen biosynthetic process GO:0032964 2 0.139
notch signaling pathway GO:0007219 35 0.139
nephron tubule morphogenesis GO:0072078 1 0.137
regulation of programmed cell death GO:0043067 101 0.136
regulation of cell communication GO:0010646 232 0.135
Mouse
negative regulation of cellular process GO:0048523 283 0.134
heart development GO:0007507 313 0.134
palate development GO:0060021 8 0.134
Mouse
determination of left right symmetry GO:0007368 179 0.133
response to corticosteroid GO:0031960 1 0.132
phosphorus metabolic process GO:0006793 109 0.132
enzyme linked receptor protein signaling pathway GO:0007167 106 0.132
Mouse
renal tubule morphogenesis GO:0061333 1 0.131
muscle organ development GO:0007517 101 0.131
sensory organ development GO:0007423 393 0.130
Zebrafish Mouse
localization of cell GO:0051674 244 0.130
epidermis development GO:0008544 48 0.129
Zebrafish
heart jogging GO:0003146 40 0.128
positive regulation of cell cycle GO:0045787 3 0.127
fin development GO:0033333 77 0.125
catechol containing compound biosynthetic process GO:0009713 2 0.124
muscle tissue development GO:0060537 110 0.123
response to oxygen containing compound GO:1901700 55 0.122
regulation of inner ear receptor cell differentiation GO:2000980 1 0.120
locus ceruleus development GO:0021703 3 0.118
circulatory system process GO:0003013 87 0.117
oligodendrocyte cell fate specification GO:0021778 4 0.116
negative regulation of cell differentiation GO:0045596 46 0.116
outflow tract morphogenesis GO:0003151 1 0.116
response to hormone GO:0009725 48 0.116
regulation of protein modification by small protein conjugation or removal GO:1903320 3 0.113
somitogenesis GO:0001756 87 0.113
anal fin development GO:0033335 1 0.112
response to glucocorticoid GO:0051384 1 0.111
negative regulation of nervous system development GO:0051961 22 0.110
eye development GO:0001654 277 0.110
Zebrafish
ectodermal placode morphogenesis GO:0071697 32 0.109
positive regulation of cell differentiation GO:0045597 30 0.106
Rat
positive regulation of notch signaling pathway GO:0045747 3 0.104
positive regulation of endothelial cell proliferation GO:0001938 1 0.104
positive regulation of muscle organ development GO:0048636 1 0.103
negative regulation of endothelial cell migration GO:0010596 1 0.103
sympathetic nervous system development GO:0048485 3 0.102
endocrine system development GO:0035270 65 0.101
Zebrafish
bmp signaling pathway involved in heart jogging GO:0003303 14 0.098
dopaminergic neuron differentiation GO:0071542 14 0.098
regulation of notch signaling pathway GO:0008593 16 0.096
locomotory behavior GO:0007626 34 0.095
regulation of axon extension GO:0030516 24 0.094
cell morphogenesis GO:0000902 289 0.093
Mouse
otolith development GO:0048840 32 0.092
negative regulation of signaling GO:0023057 96 0.092
negative regulation of cellular macromolecule biosynthetic process GO:2000113 48 0.092
positive regulation of epithelial cell proliferation GO:0050679 1 0.092
Mouse
positive regulation of epithelial cell migration GO:0010634 2 0.091
kidney development GO:0001822 92 0.090
carbohydrate derivative metabolic process GO:1901135 61 0.087
hemopoiesis GO:0030097 183 0.087
amine metabolic process GO:0009308 2 0.087
odontogenesis GO:0042476 9 0.087
phosphate containing compound metabolic process GO:0006796 108 0.086
negative regulation of nitrogen compound metabolic process GO:0051172 59 0.086
regulation of oligodendrocyte differentiation GO:0048713 1 0.086
embryonic heart tube development GO:0035050 133 0.086
response to external biotic stimulus GO:0043207 97 0.085
regulation of cell differentiation GO:0045595 142 0.085
Rat
sprouting angiogenesis GO:0002040 53 0.085
response to lipid GO:0033993 60 0.085
embryonic viscerocranium morphogenesis GO:0048703 52 0.084
innervation GO:0060384 3 0.084
protein modification process GO:0036211 100 0.082
organonitrogen compound metabolic process GO:1901564 74 0.082
tissue migration GO:0090130 37 0.081
regulation of glial cell differentiation GO:0045685 4 0.081
negative regulation of epithelial cell proliferation GO:0050680 1 0.080
craniofacial suture morphogenesis GO:0097094 2 0.080
ectodermal placode formation GO:0060788 26 0.079
Zebrafish
regulation of tube size GO:0035150 2 0.079
regulation of cellular amine metabolic process GO:0033238 0 0.079
nephron morphogenesis GO:0072028 2 0.078
ameboidal type cell migration GO:0001667 143 0.078
single organism behavior GO:0044708 24 0.077
negative regulation of mitosis GO:0045839 3 0.077
signal transduction in absence of ligand GO:0038034 1 0.077
retinal ganglion cell axon guidance GO:0031290 35 0.077
protein targeting to nucleus GO:0044744 3 0.076
response to decreased oxygen levels GO:0036293 25 0.076
positive regulation of cell communication GO:0010647 56 0.075
Mouse
positive regulation of smoothened signaling pathway GO:0045880 5 0.075
stem cell development GO:0048864 82 0.075
pituitary gland development GO:0021983 16 0.075
growth GO:0040007 174 0.074
posterior lateral line system development GO:0048915 46 0.074
bone development GO:0060348 14 0.074
Mouse
epithelial cell proliferation GO:0050673 17 0.074
Mouse
entrainment of circadian clock GO:0009649 2 0.074
regulation of skeletal muscle tissue development GO:0048641 4 0.074
vestibular receptor cell development GO:0060118 3 0.073
regulation of apoptotic process GO:0042981 98 0.073
response to endogenous stimulus GO:0009719 83 0.073
Mouse
programmed cell death GO:0012501 119 0.073
cell cycle GO:0007049 93 0.072
muscle cell development GO:0055001 115 0.072
synaptic growth at neuromuscular junction GO:0051124 2 0.072
negative regulation of apoptotic process GO:0043066 55 0.070
immune system development GO:0002520 191 0.070
urogenital system development GO:0001655 97 0.070
cell type specific apoptotic process GO:0097285 22 0.069
embryonic heart tube morphogenesis GO:0003143 108 0.068
stem cell division GO:0017145 1 0.068
positive regulation of cell adhesion GO:0045785 1 0.068
auditory receptor cell fate determination GO:0042668 2 0.068
myeloid cell differentiation GO:0030099 86 0.067
positive regulation of cell death GO:0010942 29 0.067
regulation of extrinsic apoptotic signaling pathway in absence of ligand GO:2001239 1 0.067
erk1 and erk2 cascade GO:0070371 4 0.066
response to steroid hormone GO:0048545 35 0.066
negative regulation of epithelial cell migration GO:0010633 1 0.066
regulation of mechanoreceptor differentiation GO:0045631 1 0.066
retina development in camera type eye GO:0060041 146 0.065
patterning of blood vessels GO:0001569 15 0.065
nucleocytoplasmic transport GO:0006913 4 0.065
wound healing GO:0042060 90 0.065
chemosensory behavior GO:0007635 1 0.065
cartilage morphogenesis GO:0060536 13 0.063
cell motility GO:0048870 244 0.063
negative regulation of neuron differentiation GO:0045665 10 0.062
tissue regeneration GO:0042246 74 0.062
regulation of gliogenesis GO:0014013 6 0.061
taxis GO:0042330 109 0.061
Mouse
organic acid metabolic process GO:0006082 31 0.060
cellular response to growth factor stimulus GO:0071363 39 0.059
Mouse
epithelial tube morphogenesis GO:0060562 148 0.059
regulation of anatomical structure morphogenesis GO:0022603 130 0.059
negative regulation of muscle cell differentiation GO:0051148 1 0.059
cellular response to lipid GO:0071396 39 0.058
larval development GO:0002164 2 0.057
heart morphogenesis GO:0003007 156 0.057
positive regulation of multicellular organismal process GO:0051240 52 0.057
Rat
response to growth factor GO:0070848 39 0.057
Mouse
response to biotic stimulus GO:0009607 97 0.057
regulation of cell fate specification GO:0042659 20 0.056
embryonic digestive tract morphogenesis GO:0048557 3 0.056
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 42 0.056
ventral spinal cord development GO:0021517 35 0.055
somatic stem cell maintenance GO:0035019 1 0.055
auditory receptor cell differentiation GO:0042491 15 0.055
Zebrafish
nephron epithelium morphogenesis GO:0072088 1 0.055
meiotic nuclear division GO:0007126 4 0.055
glycosaminoglycan metabolic process GO:0030203 9 0.055
endocardial cushion morphogenesis GO:0003203 3 0.054
embryonic skeletal joint development GO:0072498 3 0.054
kupffer s vesicle development GO:0070121 50 0.053
positive regulation of cellular protein metabolic process GO:0032270 22 0.053
pharyngeal system development GO:0060037 18 0.053
negative regulation of granulocyte chemotaxis GO:0071623 3 0.053
leukocyte homeostasis GO:0001776 2 0.052
myotube differentiation GO:0014902 45 0.052
regulation of catalytic activity GO:0050790 55 0.052
negative regulation of striated muscle cell differentiation GO:0051154 1 0.052
dendrite development GO:0016358 9 0.051
protein complex subunit organization GO:0071822 46 0.051
positive regulation of cell development GO:0010720 25 0.050
regulation of reproductive process GO:2000241 4 0.050
spinal cord development GO:0021510 46 0.050
regulation of protein ubiquitination GO:0031396 3 0.050
exocrine pancreas development GO:0031017 28 0.050
regulation of epithelial cell migration GO:0010632 5 0.050
positive regulation of hydrolase activity GO:0051345 13 0.050
smoothened signaling pathway GO:0007224 30 0.050
response to wounding GO:0009611 116 0.050
central nervous system neuron development GO:0021954 29 0.050
single organism nuclear import GO:1902593 3 0.049
atrial ventricular junction remodeling GO:0003294 2 0.049
carboxylic acid metabolic process GO:0019752 22 0.049
positive regulation of cell migration GO:0030335 11 0.049
regulation of cell proliferation involved in heart morphogenesis GO:2000136 2 0.049
forebrain regionalization GO:0021871 4 0.049
regulation of neuron apoptotic process GO:0043523 17 0.049
response to bacterium GO:0009617 58 0.049
cellular amine metabolic process GO:0044106 2 0.049
regulation of neuron differentiation GO:0045664 56 0.048
axon extension involved in axon guidance GO:0048846 10 0.048
heart field specification GO:0003128 1 0.048
cell migration involved in gastrulation GO:0042074 79 0.048
ventricular cardiac muscle cell development GO:0055015 5 0.048
determination of heart left right asymmetry GO:0061371 117 0.047
gabaergic neuron differentiation GO:0097154 2 0.046
regulation of erk1 and erk2 cascade GO:0070372 4 0.046
phagocytosis GO:0006909 3 0.046
anterior posterior pattern specification GO:0009952 152 0.046
negative regulation of response to stimulus GO:0048585 104 0.045
extracellular structure organization GO:0043062 27 0.045
astrocyte differentiation GO:0048708 1 0.045
neuron projection extension GO:1990138 45 0.045
myotome development GO:0061055 1 0.045
positive regulation of erk1 and erk2 cascade GO:0070374 2 0.045
endodermal cell fate determination GO:0007493 2 0.045
peripheral nervous system development GO:0007422 55 0.045
embryonic camera type eye morphogenesis GO:0048596 19 0.045
neuroblast proliferation GO:0007405 2 0.044
establishment of protein localization to organelle GO:0072594 4 0.044
regulation of multicellular organism growth GO:0040014 4 0.043
protein localization to nucleus GO:0034504 3 0.043
collagen fibril organization GO:0030199 1 0.043
neural tube development GO:0021915 62 0.043
defense response GO:0006952 47 0.043
smooth muscle tissue development GO:0048745 1 0.043
axonogenesis involved in innervation GO:0060385 1 0.043
response to fibroblast growth factor GO:0071774 22 0.043
axon extension GO:0048675 45 0.043
forebrain cell migration GO:0021885 1 0.043
ras protein signal transduction GO:0007265 7 0.043
cardiac chamber development GO:0003205 19 0.042
regulation of blood coagulation GO:0030193 1 0.042
retina morphogenesis in camera type eye GO:0060042 79 0.042
rhythmic process GO:0048511 21 0.042
negative regulation of cell communication GO:0010648 96 0.042
cardiac chamber formation GO:0003207 4 0.042
dopamine biosynthetic process GO:0042416 2 0.041
regulation of cell fate commitment GO:0010453 22 0.041
tube morphogenesis GO:0035239 349 0.041
gamete generation GO:0007276 33 0.041
peripheral nervous system neuron differentiation GO:0048934 28 0.040
detection of abiotic stimulus GO:0009582 24 0.040
regulation of neuron death GO:1901214 18 0.040
axis specification GO:0009798 43 0.040
regulation of skeletal muscle fiber development GO:0048742 2 0.040

dlx5a disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
bone development disease DOID:0080006 0 0.771
bone disease DOID:0080001 0 0.771
disease of anatomical entity DOID:7 0 0.771
musculoskeletal system disease DOID:17 0 0.771
connective tissue disease DOID:65 0 0.771
osteochondrodysplasia DOID:2256 0 0.213
dysostosis DOID:1934 0 0.127