Danio rerio

0 known processes

dpyd

dihydropyrimidine dehydrogenase

(Aliases: MGC77205,zgc:77205)

dpyd biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
small molecule metabolic process GO:0044281 77 0.285
single organism metabolic process GO:0044710 217 0.200
carboxylic acid metabolic process GO:0019752 22 0.177
organic acid metabolic process GO:0006082 31 0.151
oxoacid metabolic process GO:0043436 31 0.136
cellular aldehyde metabolic process GO:0006081 4 0.121
carboxylic acid catabolic process GO:0046395 3 0.102
single organism transport GO:0044765 206 0.094
aging GO:0007568 2 0.086
larval development GO:0002164 2 0.082
transport GO:0006810 220 0.076
organonitrogen compound metabolic process GO:1901564 74 0.071
regulation of biological quality GO:0065008 263 0.070
cellular biosynthetic process GO:0044249 286 0.069
small molecule catabolic process GO:0044282 3 0.069
biosynthetic process GO:0009058 294 0.067
regulation of protein transport GO:0051223 3 0.066
cellular response to chemical stimulus GO:0070887 157 0.066
cellular nitrogen compound metabolic process GO:0034641 290 0.066
response to chemical GO:0042221 320 0.065
cellular lipid catabolic process GO:0044242 3 0.064
cell substrate adhesion GO:0031589 4 0.061
positive regulation of transport GO:0051050 2 0.059
organic substance transport GO:0071702 58 0.059
fatty acid oxidation GO:0019395 1 0.058
cellular lipid metabolic process GO:0044255 36 0.057
establishment of localization GO:0051234 244 0.057
response to organic substance GO:0010033 153 0.057
maintenance of location GO:0051235 4 0.055
oxidation reduction process GO:0055114 41 0.054
organic substance biosynthetic process GO:1901576 289 0.054
ion transport GO:0006811 114 0.052
response to glucose GO:0009749 3 0.050
lipid catabolic process GO:0016042 4 0.050
dicarboxylic acid transport GO:0006835 1 0.047
signal transduction GO:0007165 455 0.046
cellular response to methanol GO:0071405 4 0.044
amine metabolic process GO:0009308 2 0.044
nitrogen compound metabolic process GO:0006807 319 0.043
cellular carbohydrate metabolic process GO:0044262 4 0.043
locomotion GO:0040011 313 0.043
lipid storage GO:0019915 1 0.043
organic acid catabolic process GO:0016054 3 0.041
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.041
glucose homeostasis GO:0042593 1 0.040
cellular ketone metabolic process GO:0042180 11 0.039
heterocycle metabolic process GO:0046483 290 0.039
lipid homeostasis GO:0055088 3 0.039
response to stress GO:0006950 263 0.039
regulation of multicellular organismal process GO:0051239 277 0.038
establishment of protein localization to organelle GO:0072594 4 0.038
cellular amine metabolic process GO:0044106 2 0.038
response to vitamin GO:0033273 3 0.038
lipid metabolic process GO:0006629 52 0.037
organic cyclic compound biosynthetic process GO:1901362 223 0.037
cellular response to organic substance GO:0071310 105 0.037
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.037
morphogenesis of an epithelium GO:0002009 333 0.036
hormone secretion GO:0046879 2 0.036
regulation of metabolic process GO:0019222 359 0.035
immune system process GO:0002376 241 0.035
macromolecule biosynthetic process GO:0009059 227 0.035
regulation of establishment of protein localization GO:0070201 4 0.034
phagocytosis GO:0006909 3 0.034
positive regulation of cellular amine metabolic process GO:0033240 0 0.033
regulation of primary metabolic process GO:0080090 311 0.033
oxalate transport GO:0019532 1 0.033
nucleobase containing compound metabolic process GO:0006139 274 0.033
gland development GO:0048732 143 0.033
hepaticobiliary system development GO:0061008 98 0.033
negative regulation of biological process GO:0048519 304 0.032
monocarboxylic acid catabolic process GO:0072329 3 0.031
regulation of blood vessel size GO:0050880 2 0.031
multicellular organism growth GO:0035264 4 0.031
cellular aromatic compound metabolic process GO:0006725 295 0.031
regulation of cellular amine metabolic process GO:0033238 0 0.031
energy reserve metabolic process GO:0006112 2 0.031
cellular macromolecule metabolic process GO:0044260 391 0.030
regulation of cytokine production GO:0001817 3 0.030
regulation of cellular metabolic process GO:0031323 320 0.030
response to organic cyclic compound GO:0014070 51 0.029
regulation of cellular ketone metabolic process GO:0010565 7 0.029
rna metabolic process GO:0016070 219 0.029
digestive tract development GO:0048565 265 0.029
single organism localization GO:1902578 225 0.029
neuroblast proliferation GO:0007405 2 0.029
long chain fatty acid metabolic process GO:0001676 1 0.029
cellular amino acid metabolic process GO:0006520 7 0.029
regulation of hormone secretion GO:0046883 2 0.029
regulation of gene expression GO:0010468 265 0.028
alcohol biosynthetic process GO:0046165 2 0.028
response to carbohydrate GO:0009743 3 0.028
digestive system development GO:0055123 289 0.028
carbohydrate homeostasis GO:0033500 1 0.028
regulation of transcription from rna polymerase ii promoter GO:0006357 114 0.028
tube morphogenesis GO:0035239 349 0.027
generation of neurons GO:0048699 385 0.027
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 2 0.027
cell matrix adhesion GO:0007160 4 0.027
response to monosaccharide GO:0034284 3 0.027
regulation of signal transduction GO:0009966 225 0.027
secondary metabolic process GO:0019748 3 0.027
heart development GO:0007507 313 0.027
regulation of developmental process GO:0050793 247 0.027
organic cyclic compound metabolic process GO:1901360 301 0.027
adult behavior GO:0030534 2 0.026
response to nutrient GO:0007584 3 0.026
lipid oxidation GO:0034440 1 0.026
response to endogenous stimulus GO:0009719 83 0.026
response to hexose GO:0009746 3 0.026
regulation of stem cell proliferation GO:0072091 2 0.026
positive regulation of secretion GO:0051047 1 0.025
embryonic heart tube development GO:0035050 133 0.025
positive regulation of secretion by cell GO:1903532 1 0.025
programmed cell death GO:0012501 119 0.025
digestive tract morphogenesis GO:0048546 231 0.025
regulation of cell substrate adhesion GO:0010810 1 0.025
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.025
organelle organization GO:0006996 227 0.024
regulation of multicellular organism growth GO:0040014 4 0.024
regulation of cellular amino acid metabolic process GO:0006521 0 0.024
regulation of tube size GO:0035150 2 0.024
positive regulation of catabolic process GO:0009896 4 0.024
cellular nitrogen compound biosynthetic process GO:0044271 218 0.024
response to amine GO:0014075 1 0.024
fatty acid catabolic process GO:0009062 1 0.024
hematopoietic or lymphoid organ development GO:0048534 191 0.023
growth GO:0040007 174 0.023
cellular component movement GO:0006928 335 0.023
endosomal transport GO:0016197 2 0.022
nuclear transport GO:0051169 4 0.022
vasculature development GO:0001944 278 0.022
striated muscle cell development GO:0055002 108 0.022
central nervous system development GO:0007417 387 0.022
nucleocytoplasmic transport GO:0006913 4 0.022
regulation of macromolecule metabolic process GO:0060255 317 0.022
hemostasis GO:0007599 13 0.022
response to hormone GO:0009725 48 0.021
regulation of production of molecular mediator of immune response GO:0002700 1 0.021
response to amphetamine GO:0001975 1 0.021
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.021
regulation of response to stimulus GO:0048583 269 0.021
muscle cell differentiation GO:0042692 139 0.021
cellular hormone metabolic process GO:0034754 19 0.021
symbiosis encompassing mutualism through parasitism GO:0044403 4 0.020
protein import into nucleus GO:0006606 3 0.020
homeostatic process GO:0042592 142 0.020
macromolecule localization GO:0033036 54 0.020
acylglycerol homeostasis GO:0055090 2 0.020
cellular macromolecule biosynthetic process GO:0034645 224 0.020
determination of heart left right asymmetry GO:0061371 117 0.020
regulation of nitrogen compound metabolic process GO:0051171 251 0.020
nuclear import GO:0051170 3 0.019
system process GO:0003008 185 0.019
meiotic nuclear division GO:0007126 4 0.019
negative regulation of cellular process GO:0048523 283 0.019
positive regulation of cellular catabolic process GO:0031331 3 0.019
pyruvate metabolic process GO:0006090 1 0.019
blood circulation GO:0008015 87 0.019
cellular component assembly GO:0022607 170 0.019
cellular respiration GO:0045333 3 0.019
pyrimidine containing compound metabolic process GO:0072527 3 0.019
anion transport GO:0006820 38 0.019
positive regulation of lipid metabolic process GO:0045834 1 0.019
hormone transport GO:0009914 2 0.019
cell death GO:0008219 121 0.019
transcription dna templated GO:0006351 181 0.019
regulation of transcription dna templated GO:0006355 213 0.019
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.018
gene expression GO:0010467 252 0.018
stem cell proliferation GO:0072089 4 0.018
response to drug GO:0042493 3 0.018
cellular component disassembly GO:0022411 1 0.018
negative regulation of macromolecule metabolic process GO:0010605 76 0.018
cellular response to external stimulus GO:0071496 2 0.018
organic substance catabolic process GO:1901575 28 0.018
terpenoid metabolic process GO:0006721 15 0.018
protein import GO:0017038 3 0.018
nucleic acid templated transcription GO:0097659 181 0.018
protein localization to plasma membrane GO:0072659 1 0.018
protein metabolic process GO:0019538 183 0.018
protein secretion GO:0009306 1 0.017
rna biosynthetic process GO:0032774 181 0.017
blood vessel development GO:0001568 246 0.017
modification dependent protein catabolic process GO:0019941 3 0.017
regulation of protein targeting GO:1903533 2 0.017
nucleobase containing compound biosynthetic process GO:0034654 205 0.017
striated muscle cell differentiation GO:0051146 129 0.017
apoptotic process GO:0006915 116 0.017
response to steroid hormone GO:0048545 35 0.017
cellular component biogenesis GO:0044085 178 0.017
membrane invagination GO:0010324 1 0.016
monocarboxylic acid metabolic process GO:0032787 17 0.016
protein localization to nucleus GO:0034504 3 0.016
regulation of signaling GO:0023051 235 0.016
positive regulation of cellular component biogenesis GO:0044089 3 0.016
protein polymerization GO:0051258 4 0.016
neuron differentiation GO:0030182 353 0.016
embryonic organ development GO:0048568 381 0.016
phagocytosis engulfment GO:0006911 1 0.016
protein targeting to nucleus GO:0044744 3 0.016
regulation of blood pressure GO:0008217 1 0.016
negative regulation of apoptotic process GO:0043066 55 0.016
immune system development GO:0002520 191 0.016
carbohydrate biosynthetic process GO:0016051 1 0.016
regulation of cellular carbohydrate metabolic process GO:0010675 4 0.016
peptide transport GO:0015833 1 0.016
production of molecular mediator of immune response GO:0002440 2 0.015
embryonic heart tube morphogenesis GO:0003143 108 0.015
positive regulation of immune effector process GO:0002699 3 0.015
positive regulation of cellular carbohydrate metabolic process GO:0010676 1 0.015
developmental growth GO:0048589 166 0.015
regulation of extrinsic apoptotic signaling pathway GO:2001236 3 0.015
regulation of carbohydrate metabolic process GO:0006109 4 0.015
regulation of synapse assembly GO:0051963 3 0.015
actomyosin structure organization GO:0031032 53 0.015
modification dependent macromolecule catabolic process GO:0043632 3 0.015
regulation of localization GO:0032879 104 0.015
regulation of programmed cell death GO:0043067 101 0.015
muscle structure development GO:0061061 196 0.015
neuron neuron synaptic transmission GO:0007270 1 0.015
death GO:0016265 121 0.015
response to alkaloid GO:0043279 2 0.015
regulation of wound healing GO:0061041 2 0.015
regulation of cellular biosynthetic process GO:0031326 245 0.015
regulation of rna biosynthetic process GO:2001141 213 0.015
nucleic acid metabolic process GO:0090304 244 0.015
regulation of sodium ion transport GO:0002028 2 0.015
response to vitamin b3 GO:0033552 2 0.015
cellular localization GO:0051641 97 0.015
single organism biosynthetic process GO:0044711 71 0.015
regulation of cytoplasmic transport GO:1903649 4 0.015
regulation of cell communication GO:0010646 232 0.014
cognition GO:0050890 1 0.014
cellular component morphogenesis GO:0032989 336 0.014
regulation of intracellular protein transport GO:0033157 3 0.014
intracellular signal transduction GO:0035556 85 0.014
heterocycle biosynthetic process GO:0018130 215 0.014
regulation of biosynthetic process GO:0009889 250 0.014
response to oxygen containing compound GO:1901700 55 0.014
synaptic growth at neuromuscular junction GO:0051124 2 0.014
regulation of cell activation GO:0050865 1 0.014
determination of bilateral symmetry GO:0009855 204 0.014
guanosine containing compound catabolic process GO:1901069 2 0.014
retinoid metabolic process GO:0001523 15 0.014
regulation of systemic arterial blood pressure GO:0003073 1 0.014
guanosine containing compound metabolic process GO:1901068 4 0.014
regulation of circadian rhythm GO:0042752 4 0.014
regulation of apoptotic process GO:0042981 98 0.014
negative regulation of response to stimulus GO:0048585 104 0.014
embryonic organ morphogenesis GO:0048562 274 0.014
regulation of neural precursor cell proliferation GO:2000177 3 0.014
multicellular organismal response to stress GO:0033555 2 0.014
negative regulation of nucleocytoplasmic transport GO:0046823 2 0.014
kidney development GO:0001822 92 0.014
response to xenobiotic stimulus GO:0009410 45 0.014
single organism nuclear import GO:1902593 3 0.014
adherens junction organization GO:0034332 4 0.014
glucose import GO:0046323 2 0.014
macromolecular complex subunit organization GO:0043933 74 0.014
extrinsic apoptotic signaling pathway GO:0097191 3 0.014
cellular response to endogenous stimulus GO:0071495 68 0.014
negative regulation of cellular metabolic process GO:0031324 77 0.014
response to nitrogen compound GO:1901698 19 0.013
positive regulation of cell adhesion GO:0045785 1 0.013
post embryonic organ development GO:0048569 4 0.013
positive regulation of erk1 and erk2 cascade GO:0070374 2 0.013
autophagy GO:0006914 4 0.013
regulation of cell death GO:0010941 103 0.013
circulatory system process GO:0003013 87 0.013
determination of left right symmetry GO:0007368 179 0.013
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 4 0.013
cellular amide metabolic process GO:0043603 4 0.013
cellular response to extracellular stimulus GO:0031668 2 0.013
regulation of lipid transport GO:0032368 4 0.013
muscle cell development GO:0055001 115 0.013
gastrulation GO:0007369 208 0.013
positive regulation of cell substrate adhesion GO:0010811 1 0.013
epithelial tube morphogenesis GO:0060562 148 0.013
regulation of system process GO:0044057 40 0.013
regulation of nucleocytoplasmic transport GO:0046822 2 0.013
specification of symmetry GO:0009799 204 0.013
establishment of protein localization to plasma membrane GO:0090002 1 0.013
aromatic compound biosynthetic process GO:0019438 217 0.013
transcription from rna polymerase ii promoter GO:0006366 80 0.013
regulation of protein import into nucleus GO:0042306 2 0.013
cellular protein metabolic process GO:0044267 129 0.013
heart morphogenesis GO:0003007 156 0.012
meiotic cell cycle process GO:1903046 3 0.012
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.012
protein homooligomerization GO:0051260 3 0.012
regulation of gtpase activity GO:0043087 2 0.012
cellular response to organic cyclic compound GO:0071407 38 0.012
chemical homeostasis GO:0048878 49 0.012
embryo development ending in birth or egg hatching GO:0009792 271 0.012
hormone biosynthetic process GO:0042446 3 0.012
cellular catabolic process GO:0044248 27 0.012
regulation of nucleotide catabolic process GO:0030811 2 0.012
regulation of nucleic acid templated transcription GO:1903506 213 0.012
cellular response to hormone stimulus GO:0032870 39 0.012
regulation of reproductive process GO:2000241 4 0.012
lipid digestion GO:0044241 3 0.012
monoamine transport GO:0015844 1 0.012
regulation of i kappab kinase nf kappab signaling GO:0043122 4 0.011
b cell mediated immunity GO:0019724 3 0.011
heart looping GO:0001947 94 0.011
erk1 and erk2 cascade GO:0070371 4 0.011
peptidyl lysine acetylation GO:0018394 2 0.011
response to lipid GO:0033993 60 0.011
ubiquitin dependent protein catabolic process GO:0006511 3 0.011
positive regulation of multicellular organismal process GO:0051240 52 0.011
positive regulation of cellular metabolic process GO:0031325 94 0.011
peptide metabolic process GO:0006518 1 0.011
regulation of macromolecule biosynthetic process GO:0010556 225 0.011
liver development GO:0001889 96 0.011
negative regulation of protein phosphorylation GO:0001933 4 0.011
chemosensory behavior GO:0007635 1 0.011
organic anion transport GO:0015711 15 0.011
cellular response to steroid hormone stimulus GO:0071383 31 0.011
protein heterooligomerization GO:0051291 1 0.011
urogenital system development GO:0001655 97 0.011
endocrine hormone secretion GO:0060986 2 0.011
lymphocyte proliferation GO:0046651 1 0.011
gtp catabolic process GO:0006184 2 0.011
negative regulation of dna metabolic process GO:0051053 4 0.011
negative regulation of nitrogen compound metabolic process GO:0051172 59 0.011
cell migration GO:0016477 237 0.011
positive regulation of gtp catabolic process GO:0033126 1 0.011
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.011
regulation of hormone levels GO:0010817 21 0.011
response to wounding GO:0009611 116 0.011
localization of cell GO:0051674 244 0.011
gtp metabolic process GO:0046039 4 0.011
blood vessel morphogenesis GO:0048514 216 0.011
negative regulation of intracellular protein transport GO:0090317 3 0.010
spermatid differentiation GO:0048515 2 0.010
cellular response to nutrient levels GO:0031669 2 0.010
response to bacterium GO:0009617 58 0.010
regulation of rna metabolic process GO:0051252 224 0.010
renal system development GO:0072001 94 0.010
epithelial cell differentiation GO:0030855 116 0.010
negative regulation of metabolic process GO:0009892 86 0.010
nuclear migration GO:0007097 3 0.010
inositol lipid mediated signaling GO:0048017 2 0.010
negative regulation of programmed cell death GO:0043069 58 0.010

dpyd disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 0 0.058
retinal disease DOID:5679 0 0.022
sensory system disease DOID:0050155 0 0.022
disease of anatomical entity DOID:7 0 0.022
eye and adnexa disease DOID:1492 0 0.022
nervous system disease DOID:863 0 0.022
eye disease DOID:5614 0 0.022
inherited metabolic disorder DOID:655 0 0.020
retinal degeneration DOID:8466 0 0.015
immune system disease DOID:2914 0 0.014
hematopoietic system disease DOID:74 0 0.014
cancer DOID:162 0 0.010
disease of cellular proliferation DOID:14566 0 0.010
organ system cancer DOID:0050686 0 0.010