Danio rerio

0 known processes

drgx

dorsal root ganglia homeobox

(Aliases: prrxl1)

drgx biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cell part morphogenesis GO:0032990 246 0.678
Mouse
cellular component morphogenesis GO:0032989 336 0.536
Mouse
cell projection organization GO:0030030 284 0.530
Mouse
generation of neurons GO:0048699 385 0.528
Zebrafish Mouse
axonogenesis GO:0007409 152 0.447
Mouse
cell morphogenesis GO:0000902 289 0.447
Mouse
regulation of nitrogen compound metabolic process GO:0051171 251 0.423
developmental growth involved in morphogenesis GO:0060560 86 0.316
axon guidance GO:0007411 86 0.314
Mouse
axon development GO:0061564 166 0.301
Mouse
regulation of neurogenesis GO:0050767 87 0.284
sympathetic nervous system development GO:0048485 3 0.278
Zebrafish
signal transduction GO:0007165 455 0.198
neuron development GO:0048666 262 0.192
Mouse
cell surface receptor signaling pathway GO:0007166 325 0.192
cell morphogenesis involved in differentiation GO:0000904 195 0.181
Mouse
cell migration GO:0016477 237 0.170
Mouse
gene expression GO:0010467 252 0.167
Zebrafish
cellular component movement GO:0006928 335 0.159
Mouse
cognition GO:0050890 1 0.149
detection of stimulus GO:0051606 29 0.146
Mouse
detection of stimulus involved in sensory perception GO:0050906 21 0.144
cell motility GO:0048870 244 0.137
Mouse
neuron differentiation GO:0030182 353 0.136
Zebrafish Mouse
stem cell proliferation GO:0072089 4 0.131
regulation of biological quality GO:0065008 263 0.126
regulation of response to stimulus GO:0048583 269 0.125
regulation of biosynthetic process GO:0009889 250 0.123
cell projection morphogenesis GO:0048858 244 0.121
Mouse
regulation of cell differentiation GO:0045595 142 0.121
chemosensory behavior GO:0007635 1 0.117
multicellular organismal response to stress GO:0033555 2 0.115
autonomic nervous system development GO:0048483 19 0.110
Zebrafish
nucleobase containing compound biosynthetic process GO:0034654 205 0.110
embryonic organ development GO:0048568 381 0.102
regulation of meiotic cell cycle GO:0051445 1 0.102
sensory perception of pain GO:0019233 1 0.096
taxis GO:0042330 109 0.095
Mouse
response to external stimulus GO:0009605 264 0.093
Mouse
response to chemical GO:0042221 320 0.091
Mouse
neuron projection guidance GO:0097485 86 0.081
Mouse
biosynthetic process GO:0009058 294 0.081
regulation of neuron differentiation GO:0045664 56 0.077
neural tube development GO:0021915 62 0.074
neuron projection development GO:0031175 180 0.074
Mouse
regulation of cell morphogenesis involved in differentiation GO:0010769 38 0.073
female sex differentiation GO:0046660 4 0.073
regulation of neuron projection development GO:0010975 40 0.069
locomotion GO:0040011 313 0.069
Mouse
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.069
Mouse
neuroblast proliferation GO:0007405 2 0.067
chemotaxis GO:0006935 104 0.066
Mouse
nerve development GO:0021675 45 0.066
Mouse
aromatic compound biosynthetic process GO:0019438 217 0.064
neuron projection morphogenesis GO:0048812 161 0.063
Mouse
camp biosynthetic process GO:0006171 11 0.062
regulation of multicellular organismal process GO:0051239 277 0.061
smooth muscle contraction GO:0006939 2 0.060
developmental cell growth GO:0048588 52 0.059
regulation of metal ion transport GO:0010959 4 0.058
regulation of cellular metabolic process GO:0031323 320 0.058
cranial nerve development GO:0021545 42 0.057
Mouse
heterocycle biosynthetic process GO:0018130 215 0.057
detection of external stimulus GO:0009581 24 0.055
Mouse
central nervous system myelination GO:0022010 2 0.055
behavior GO:0007610 74 0.054
regulation of nervous system development GO:0051960 90 0.054
organic substance biosynthetic process GO:1901576 289 0.053
metal ion transport GO:0030001 58 0.052
chordate embryonic development GO:0043009 271 0.052
regulation of multicellular organismal development GO:2000026 223 0.052
cation transmembrane transport GO:0098655 65 0.051
transcription dna templated GO:0006351 181 0.051
adult behavior GO:0030534 2 0.050
immune system process GO:0002376 241 0.050
regulation of dendrite development GO:0050773 3 0.048
cellular nitrogen compound metabolic process GO:0034641 290 0.048
nucleobase containing compound metabolic process GO:0006139 274 0.048
regulation of synaptic plasticity GO:0048167 1 0.047
regulation of cell development GO:0060284 100 0.047
centrosome cycle GO:0007098 1 0.046
regulation of macromolecule metabolic process GO:0060255 317 0.046
Zebrafish
regulation of transcription dna templated GO:0006355 213 0.045
central nervous system neuron axonogenesis GO:0021955 18 0.045
neurological system process GO:0050877 62 0.044
Mouse
regulation of axonogenesis GO:0050770 32 0.043
rna biosynthetic process GO:0032774 181 0.043
tube morphogenesis GO:0035239 349 0.043
cellular biosynthetic process GO:0044249 286 0.043
forebrain cell migration GO:0021885 1 0.043
camera type eye development GO:0043010 222 0.042
muscle system process GO:0003012 20 0.042
regulation of cellular biosynthetic process GO:0031326 245 0.042
homophilic cell adhesion via plasma membrane adhesion molecules GO:0007156 4 0.042
cellular response to chemical stimulus GO:0070887 157 0.041
regulation of metabolic process GO:0019222 359 0.041
Zebrafish
regulation of anatomical structure morphogenesis GO:0022603 130 0.041
detection of temperature stimulus GO:0016048 0 0.040
Mouse
transmembrane transport GO:0055085 120 0.040
heterocycle metabolic process GO:0046483 290 0.040
guanosine containing compound catabolic process GO:1901069 2 0.039
camera type eye morphogenesis GO:0048593 108 0.039
calcium ion transport GO:0006816 18 0.039
skeletal muscle fiber development GO:0048741 35 0.038
regulation of primary metabolic process GO:0080090 311 0.038
embryonic organ morphogenesis GO:0048562 274 0.037
response to drug GO:0042493 3 0.037
nucleic acid metabolic process GO:0090304 244 0.037
retina development in camera type eye GO:0060041 146 0.037
localization of cell GO:0051674 244 0.037
Mouse
hematopoietic or lymphoid organ development GO:0048534 191 0.037
response to carbohydrate GO:0009743 3 0.037
medulla oblongata development GO:0021550 4 0.037
nucleoside phosphate biosynthetic process GO:1901293 21 0.037
immune system development GO:0002520 191 0.036
response to stress GO:0006950 263 0.036
detection of abiotic stimulus GO:0009582 24 0.036
Mouse
sensory organ development GO:0007423 393 0.035
single organism behavior GO:0044708 24 0.035
morphogenesis of an epithelium GO:0002009 333 0.035
inorganic cation transmembrane transport GO:0098662 50 0.035
embryonic heart tube development GO:0035050 133 0.035
embryonic epithelial tube formation GO:0001838 17 0.035
system process GO:0003008 185 0.035
Mouse
regulation of cell communication GO:0010646 232 0.034
sensory perception of chemical stimulus GO:0007606 3 0.034
diencephalon development GO:0021536 58 0.034
divalent inorganic cation transport GO:0072511 21 0.034
epithelial tube morphogenesis GO:0060562 148 0.033
organonitrogen compound metabolic process GO:1901564 74 0.033
protein heterooligomerization GO:0051291 1 0.033
myotube cell development GO:0014904 35 0.033
organic cyclic compound metabolic process GO:1901360 301 0.033
regulation of macromolecule biosynthetic process GO:0010556 225 0.033
cyclic nucleotide metabolic process GO:0009187 18 0.033
hemopoiesis GO:0030097 183 0.033
nucleic acid templated transcription GO:0097659 181 0.033
female gonad development GO:0008585 4 0.033
gtp metabolic process GO:0046039 4 0.033
central nervous system development GO:0007417 387 0.032
Zebrafish Mouse
regulation of developmental process GO:0050793 247 0.032
convergent extension GO:0060026 118 0.032
calcium ion transmembrane transport GO:0070588 13 0.032
peripheral nervous system neuron differentiation GO:0048934 28 0.031
calcium mediated signaling GO:0019722 2 0.031
positive regulation of camp biosynthetic process GO:0030819 2 0.031
neuron projection extension GO:1990138 45 0.031
skeletal system morphogenesis GO:0048705 102 0.031
regulation of dendrite morphogenesis GO:0048814 3 0.030
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.030
gabaergic neuron differentiation GO:0097154 2 0.030
detection of mechanical stimulus involved in sensory perception GO:0050974 11 0.030
neuromuscular synaptic transmission GO:0007274 2 0.029
phosphate containing compound metabolic process GO:0006796 108 0.029
regulation of circadian rhythm GO:0042752 4 0.029
cation transport GO:0006812 81 0.029
transmission of nerve impulse GO:0019226 19 0.029
negative regulation of gene expression GO:0010629 65 0.029
detection of temperature stimulus involved in sensory perception GO:0050961 0 0.029
nuclear migration GO:0007097 3 0.029
collateral sprouting in absence of injury GO:0048669 4 0.028
cellular aromatic compound metabolic process GO:0006725 295 0.028
nitrogen compound metabolic process GO:0006807 319 0.028
organelle organization GO:0006996 227 0.028
organic cyclic compound biosynthetic process GO:1901362 223 0.028
macromolecule biosynthetic process GO:0009059 227 0.027
ribonucleotide biosynthetic process GO:0009260 20 0.027
regulation of gene expression GO:0010468 265 0.027
Zebrafish
regulation of cellular component organization GO:0051128 86 0.026
positive regulation of peptidyl tyrosine phosphorylation GO:0050731 1 0.026
regeneration GO:0031099 91 0.026
digestive system development GO:0055123 289 0.026
cellular protein metabolic process GO:0044267 129 0.025
regulation of neural precursor cell proliferation GO:2000177 3 0.025
ion transmembrane transport GO:0034220 91 0.025
microtubule organizing center organization GO:0031023 1 0.025
cellular component assembly GO:0022607 170 0.025
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.024
regulation of signaling GO:0023051 235 0.024
establishment of localization GO:0051234 244 0.024
circulatory system process GO:0003013 87 0.024
stem cell differentiation GO:0048863 117 0.024
transcription from rna polymerase ii promoter GO:0006366 80 0.024
regulation of nucleic acid templated transcription GO:1903506 213 0.024
protein metabolic process GO:0019538 183 0.023
vasculature development GO:0001944 278 0.023
nuclear transport GO:0051169 4 0.023
inorganic ion transmembrane transport GO:0098660 57 0.023
protein modification process GO:0036211 100 0.023
multi organism process GO:0051704 134 0.023
positive regulation of cell adhesion GO:0045785 1 0.023
regulation of dna replication GO:0006275 3 0.022
maintenance of location GO:0051235 4 0.022
regulation of cell projection organization GO:0031344 44 0.022
peripheral nervous system neuron development GO:0048935 22 0.022
rna metabolic process GO:0016070 219 0.022
regulation of rna metabolic process GO:0051252 224 0.022
sensory perception of mechanical stimulus GO:0050954 16 0.022
Mouse
hindbrain development GO:0030902 91 0.022
Zebrafish
response to cold GO:0009409 4 0.021
gland development GO:0048732 143 0.021
development of primary female sexual characteristics GO:0046545 4 0.021
cellular response to organic substance GO:0071310 105 0.021
ameboidal type cell migration GO:0001667 143 0.021
regulation of signal transduction GO:0009966 225 0.021
peripheral nervous system neuron axonogenesis GO:0048936 13 0.021
positive regulation of cellular process GO:0048522 201 0.021
mechanosensory behavior GO:0007638 2 0.021
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.021
central nervous system neuron differentiation GO:0021953 74 0.020
multicellular organismal signaling GO:0035637 22 0.020
central nervous system neuron development GO:0021954 29 0.020
cellular response to methanol GO:0071405 4 0.020
embryonic skeletal system development GO:0048706 97 0.020
regulation of axon extension GO:0030516 24 0.020
cellular macromolecule biosynthetic process GO:0034645 224 0.020
meiotic nuclear division GO:0007126 4 0.020
regulation of neuronal synaptic plasticity GO:0048168 1 0.020
angiogenesis GO:0001525 158 0.020
regulation of ion transmembrane transporter activity GO:0032412 2 0.019
single organism localization GO:1902578 225 0.019
hard palate development GO:0060022 4 0.019
lipid storage GO:0019915 1 0.019
positive regulation of cellular component biogenesis GO:0044089 3 0.019
phasic smooth muscle contraction GO:0014821 1 0.019
peptidyl threonine modification GO:0018210 1 0.018
positive regulation of notch signaling pathway GO:0045747 3 0.018
establishment of blood brain barrier GO:0060856 2 0.018
regionalization GO:0003002 274 0.018
anatomical structure arrangement GO:0048532 2 0.018
macromolecule modification GO:0043412 111 0.018
cellular macromolecule metabolic process GO:0044260 391 0.018
pectoral fin morphogenesis GO:0035138 29 0.018
neuronal action potential GO:0019228 18 0.018
retina morphogenesis in camera type eye GO:0060042 79 0.018
gtp catabolic process GO:0006184 2 0.018
regulation of cellular ketone metabolic process GO:0010565 7 0.018
hatching gland development GO:0048785 3 0.018
negative regulation of biosynthetic process GO:0009890 55 0.018
muscle fiber development GO:0048747 52 0.018
sprouting angiogenesis GO:0002040 53 0.018
axon ensheathment in central nervous system GO:0032291 2 0.018
regulation of cytoplasmic transport GO:1903649 4 0.018
branching morphogenesis of a nerve GO:0048755 4 0.018
regulation of protein complex assembly GO:0043254 3 0.018
peptidyl threonine phosphorylation GO:0018107 1 0.017
response to abiotic stimulus GO:0009628 122 0.017
Mouse
lamellipodium organization GO:0097581 1 0.017
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 42 0.017
axonal defasciculation GO:0007414 2 0.017
forebrain development GO:0030900 96 0.017
regulation of gtp catabolic process GO:0033124 2 0.017
regulation of cyclic nucleotide biosynthetic process GO:0030802 15 0.017
cellular protein modification process GO:0006464 100 0.017
regulation of cell shape GO:0008360 1 0.017
carbohydrate derivative metabolic process GO:1901135 61 0.017
cellular nitrogen compound biosynthetic process GO:0044271 218 0.017
guanosine containing compound metabolic process GO:1901068 4 0.017
blood vessel morphogenesis GO:0048514 216 0.017
digestive tract mesoderm development GO:0007502 1 0.017
posterior lateral line neuromast mantle cell differentiation GO:0048924 1 0.017
midbrain development GO:0030901 28 0.016
positive regulation of nucleobase containing compound metabolic process GO:0045935 69 0.016
adherens junction organization GO:0034332 4 0.016
sympathetic ganglion development GO:0061549 2 0.016
Zebrafish
regulation of tube size GO:0035150 2 0.016
negative regulation of macromolecule biosynthetic process GO:0010558 48 0.016
negative regulation of nitrogen compound metabolic process GO:0051172 59 0.016
divalent metal ion transport GO:0070838 20 0.016
immune response regulating signaling pathway GO:0002764 5 0.016
locomotor rhythm GO:0045475 3 0.016
hair cell differentiation GO:0035315 32 0.016
response to organic substance GO:0010033 153 0.016
regulation of axon extension involved in axon guidance GO:0048841 6 0.016
regulation of cellular amine metabolic process GO:0033238 0 0.016
regulation of binding GO:0051098 3 0.016
mesoderm development GO:0007498 88 0.016
stem cell division GO:0017145 1 0.016
regulation of cell size GO:0008361 29 0.015
negative regulation of biological process GO:0048519 304 0.015
cyclic nucleotide biosynthetic process GO:0009190 18 0.015
sensory perception GO:0007600 39 0.015
Mouse
regulation of reproductive process GO:2000241 4 0.015
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 2 0.015
regulation of neuron migration GO:2001222 2 0.015
regulation of gtpase activity GO:0043087 2 0.015
positive regulation of cellular amine metabolic process GO:0033240 0 0.015
negative regulation of cellular process GO:0048523 283 0.015
response to antibiotic GO:0046677 1 0.015
negative chemotaxis GO:0050919 1 0.015
lymph vessel morphogenesis GO:0036303 25 0.015
ovulation cycle GO:0042698 2 0.014
carbohydrate biosynthetic process GO:0016051 1 0.014
regulation of intracellular signal transduction GO:1902531 57 0.014
eye development GO:0001654 277 0.014
tube closure GO:0060606 1 0.014
negative regulation of multicellular organismal process GO:0051241 69 0.014
single organism metabolic process GO:0044710 217 0.014
lymphangiogenesis GO:0001946 25 0.014
centrosome localization GO:0051642 1 0.014
outflow tract morphogenesis GO:0003151 1 0.014
brain development GO:0007420 293 0.014
Zebrafish
transport GO:0006810 220 0.014
regulation of cellular amino acid metabolic process GO:0006521 0 0.014
cellular amine metabolic process GO:0044106 2 0.014
positive regulation of transcription dna templated GO:0045893 57 0.014
myeloid cell differentiation GO:0030099 86 0.014
purine nucleotide biosynthetic process GO:0006164 20 0.014
wound healing GO:0042060 90 0.014
receptor internalization GO:0031623 2 0.013
neuromuscular process controlling balance GO:0050885 3 0.013
epithelial tube formation GO:0072175 19 0.013
cell growth GO:0016049 57 0.013
regulation of cellular protein metabolic process GO:0032268 52 0.013
organophosphate metabolic process GO:0019637 37 0.013
positive regulation of camp metabolic process GO:0030816 2 0.013
regulation of cell migration involved in sprouting angiogenesis GO:0090049 3 0.013
blood circulation GO:0008015 87 0.013
morphogenesis of embryonic epithelium GO:0016331 30 0.013
regulation of collateral sprouting in absence of injury GO:0048696 4 0.013
axon extension involved in axon guidance GO:0048846 10 0.013
erythrocyte homeostasis GO:0034101 55 0.013
aging GO:0007568 2 0.013
negative regulation of dna metabolic process GO:0051053 4 0.013
embryonic pectoral fin morphogenesis GO:0035118 24 0.013
response to biotic stimulus GO:0009607 97 0.013
homeostatic process GO:0042592 142 0.013
endocrine system development GO:0035270 65 0.013
polarized epithelial cell differentiation GO:0030859 4 0.013
detection of chemical stimulus involved in sensory perception GO:0050907 3 0.013
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.013
phototransduction GO:0007602 2 0.013
cellular amide metabolic process GO:0043603 4 0.012
organonitrogen compound biosynthetic process GO:1901566 47 0.012
synaptic growth at neuromuscular junction GO:0051124 2 0.012
regulation of ras gtpase activity GO:0032318 2 0.012
organelle transport along microtubule GO:0072384 1 0.012
myotube differentiation GO:0014902 45 0.012
inner ear receptor cell differentiation GO:0060113 29 0.012
ovulation cycle process GO:0022602 2 0.012
ectodermal placode development GO:0071696 37 0.012
positive regulation of glucose import GO:0046326 1 0.012
olfactory lobe development GO:0021988 4 0.012
collateral sprouting GO:0048668 9 0.012
regulation of cellular component movement GO:0051270 55 0.012
dendrite guidance GO:0070983 0 0.012
motor neuron axon guidance GO:0008045 23 0.012
neural precursor cell proliferation GO:0061351 20 0.012
ribose phosphate biosynthetic process GO:0046390 20 0.012
cell cycle GO:0007049 93 0.012
heart contraction GO:0060047 71 0.012
regulation of synapse assembly GO:0051963 3 0.012
muscle contraction GO:0006936 18 0.012
dorsal ventral pattern formation GO:0009953 125 0.012
organism emergence from protective structure GO:0071684 4 0.012
synaptic vesicle localization GO:0097479 1 0.012
regulation of calcium ion transport GO:0051924 2 0.012
embryonic cranial skeleton morphogenesis GO:0048701 90 0.012
establishment of synaptic vesicle localization GO:0097480 1 0.012
synaptic transmission GO:0007268 35 0.012
segmentation GO:0035282 97 0.012
positive regulation of cyclic nucleotide biosynthetic process GO:0030804 8 0.012
phagocytosis GO:0006909 3 0.012
amine metabolic process GO:0009308 2 0.012
regulation of cell activation GO:0050865 1 0.011
cell cell junction maintenance GO:0045217 1 0.011
peristalsis GO:0030432 1 0.011
regulation of neurotransmitter transport GO:0051588 1 0.011
glucose import GO:0046323 2 0.011
peripheral nervous system development GO:0007422 55 0.011
ubiquitin dependent protein catabolic process GO:0006511 3 0.011
response to hydrogen peroxide GO:0042542 3 0.011
negative regulation of transcription dna templated GO:0045892 45 0.011
primary neural tube formation GO:0014020 1 0.011
response to wounding GO:0009611 116 0.011
negative regulation of nucleobase containing compound metabolic process GO:0045934 59 0.011
sensory neuron axon guidance GO:0097374 3 0.011
regulation of cyclic nucleotide metabolic process GO:0030799 15 0.011
regulation of axon guidance GO:1902667 8 0.011
regulation of blood pressure GO:0008217 1 0.011
positive regulation of biological process GO:0048518 253 0.011
Zebrafish
cellular component biogenesis GO:0044085 178 0.011
positive regulation of rna biosynthetic process GO:1902680 57 0.011
phosphorus metabolic process GO:0006793 109 0.011
skin development GO:0043588 54 0.011
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.011
eye morphogenesis GO:0048592 144 0.011
entrainment of circadian clock GO:0009649 2 0.011
positive regulation of signal transduction GO:0009967 56 0.011
semicircular canal development GO:0060872 24 0.011
axon cargo transport GO:0008088 2 0.011
facial nerve morphogenesis GO:0021610 1 0.011
rhombomere 5 development GO:0021571 4 0.010
phosphorylation GO:0016310 69 0.010
regulation of cell cycle GO:0051726 52 0.010
neuron projection regeneration GO:0031102 16 0.010
cellular protein catabolic process GO:0044257 4 0.010
camp metabolic process GO:0046058 11 0.010
exocytosis GO:0006887 1 0.010
positive regulation of nucleotide biosynthetic process GO:0030810 8 0.010
convergent extension involved in gastrulation GO:0060027 71 0.010
positive regulation of secretion GO:0051047 1 0.010
compound eye development GO:0048749 2 0.010
mitotic cell cycle embryonic GO:0045448 2 0.010
membrane invagination GO:0010324 1 0.010

drgx disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.117
nervous system disease DOID:863 0 0.026
cancer DOID:162 0 0.020
disease of cellular proliferation DOID:14566 0 0.020
organ system cancer DOID:0050686 0 0.012