Danio rerio

0 known processes

dtna

dystrobrevin, alpha

(Aliases: adtn,atnb)

dtna biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
generation of neurons GO:0048699 385 0.143
neuron differentiation GO:0030182 353 0.132
signal transduction GO:0007165 455 0.117
neuron projection development GO:0031175 180 0.112
cell projection organization GO:0030030 284 0.103
larval development GO:0002164 2 0.098
morphogenesis of an epithelium GO:0002009 333 0.084
cellular component morphogenesis GO:0032989 336 0.084
Worm
neuron development GO:0048666 262 0.080
organic substance biosynthetic process GO:1901576 289 0.080
aging GO:0007568 2 0.079
stem cell maintenance GO:0019827 4 0.076
locomotion GO:0040011 313 0.075
Worm
regulation of metabolic process GO:0019222 359 0.075
digestive system development GO:0055123 289 0.074
post embryonic organ development GO:0048569 4 0.069
cell part morphogenesis GO:0032990 246 0.066
cell motility GO:0048870 244 0.063
central nervous system development GO:0007417 387 0.063
localization of cell GO:0051674 244 0.062
negative regulation of biological process GO:0048519 304 0.060
cognition GO:0050890 1 0.060
negative regulation of cellular process GO:0048523 283 0.059
nucleic acid templated transcription GO:0097659 181 0.059
gene expression GO:0010467 252 0.059
heart development GO:0007507 313 0.055
determination of left right symmetry GO:0007368 179 0.052
eye development GO:0001654 277 0.052
neurotransmitter transport GO:0006836 2 0.051
Worm
cellular component movement GO:0006928 335 0.051
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.050
specification of symmetry GO:0009799 204 0.049
regulation of nitrogen compound metabolic process GO:0051171 251 0.049
cell migration GO:0016477 237 0.048
organelle organization GO:0006996 227 0.048
Worm
heterocycle biosynthetic process GO:0018130 215 0.047
neuron projection morphogenesis GO:0048812 161 0.046
sensory organ development GO:0007423 393 0.045
establishment of localization GO:0051234 244 0.045
Worm
cellular aromatic compound metabolic process GO:0006725 295 0.045
axon development GO:0061564 166 0.045
regulation of developmental process GO:0050793 247 0.045
organic cyclic compound biosynthetic process GO:1901362 223 0.044
tube morphogenesis GO:0035239 349 0.044
cellular macromolecule biosynthetic process GO:0034645 224 0.043
response to external stimulus GO:0009605 264 0.043
organic cyclic compound metabolic process GO:1901360 301 0.042
cellular nitrogen compound biosynthetic process GO:0044271 218 0.042
biosynthetic process GO:0009058 294 0.042
cell morphogenesis involved in differentiation GO:0000904 195 0.041
regulation of transcription dna templated GO:0006355 213 0.041
nucleic acid metabolic process GO:0090304 244 0.041
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.041
regulation of biological quality GO:0065008 263 0.040
Worm
heterocycle metabolic process GO:0046483 290 0.039
cell projection morphogenesis GO:0048858 244 0.039
macromolecule biosynthetic process GO:0009059 227 0.039
rna metabolic process GO:0016070 219 0.039
single organism transport GO:0044765 206 0.038
Worm
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.038
single organism metabolic process GO:0044710 217 0.038
cell morphogenesis GO:0000902 289 0.038
regulation of primary metabolic process GO:0080090 311 0.038
cellular nitrogen compound metabolic process GO:0034641 290 0.038
embryonic organ development GO:0048568 381 0.038
system process GO:0003008 185 0.037
regulation of signaling GO:0023051 235 0.037
Worm
muscle structure development GO:0061061 196 0.036
Worm
positive regulation of biological process GO:0048518 253 0.036
Worm
nitrogen compound metabolic process GO:0006807 319 0.036
regulation of cellular biosynthetic process GO:0031326 245 0.036
regulation of cell differentiation GO:0045595 142 0.036
digestive tract development GO:0048565 265 0.035
regulation of rna biosynthetic process GO:2001141 213 0.035
regulation of signal transduction GO:0009966 225 0.034
regulation of anatomical structure morphogenesis GO:0022603 130 0.034
kupffer s vesicle development GO:0070121 50 0.033
regulation of macromolecule metabolic process GO:0060255 317 0.033
positive regulation of cellular process GO:0048522 201 0.033
Worm
transmembrane transport GO:0055085 120 0.032
Worm
single organism localization GO:1902578 225 0.032
Worm
neuron neuron synaptic transmission GO:0007270 1 0.032
amine metabolic process GO:0009308 2 0.032
regulation of cell shape GO:0008360 1 0.032
regulation of macromolecule biosynthetic process GO:0010556 225 0.032
transcription dna templated GO:0006351 181 0.032
single organism organelle organization GO:1902589 199 0.032
Worm
regulation of rna metabolic process GO:0051252 224 0.032
determination of bilateral symmetry GO:0009855 204 0.032
nucleobase containing compound metabolic process GO:0006139 274 0.031
cellular component assembly involved in morphogenesis GO:0010927 107 0.031
Worm
cellular macromolecule metabolic process GO:0044260 391 0.030
golgi vesicle transport GO:0048193 3 0.030
embryonic organ morphogenesis GO:0048562 274 0.030
compound eye development GO:0048749 2 0.030
somatic muscle development GO:0007525 4 0.030
brain development GO:0007420 293 0.030
cellular amine metabolic process GO:0044106 2 0.030
regulation of multicellular organismal process GO:0051239 277 0.029
nuclear transport GO:0051169 4 0.029
cellular component biogenesis GO:0044085 178 0.029
Worm
stem cell differentiation GO:0048863 117 0.029
gtp metabolic process GO:0046039 4 0.028
regulation of gene expression GO:0010468 265 0.028
regulation of neural precursor cell proliferation GO:2000177 3 0.028
protein import GO:0017038 3 0.028
regulation of biosynthetic process GO:0009889 250 0.028
transport GO:0006810 220 0.028
Worm
neurological system process GO:0050877 62 0.028
nucleobase containing compound biosynthetic process GO:0034654 205 0.028
head development GO:0060322 303 0.028
cell matrix adhesion GO:0007160 4 0.027
regulation of cellular amine metabolic process GO:0033238 0 0.027
forebrain cell migration GO:0021885 1 0.027
maintenance of location GO:0051235 4 0.027
muscle organ development GO:0007517 101 0.027
regulation of cellular metabolic process GO:0031323 320 0.026
death GO:0016265 121 0.026
guanosine containing compound metabolic process GO:1901068 4 0.026
nucleocytoplasmic transport GO:0006913 4 0.026
neurotransmitter secretion GO:0007269 2 0.026
regulation of nucleic acid templated transcription GO:1903506 213 0.025
cellular biosynthetic process GO:0044249 286 0.025
stem cell proliferation GO:0072089 4 0.025
protein metabolic process GO:0019538 183 0.025
endosomal transport GO:0016197 2 0.025
adult behavior GO:0030534 2 0.025
synaptic growth at neuromuscular junction GO:0051124 2 0.025
muscle cell development GO:0055001 115 0.025
Worm
response to stress GO:0006950 263 0.025
female sex differentiation GO:0046660 4 0.025
establishment of localization in cell GO:0051649 77 0.025
regulation of cellular ketone metabolic process GO:0010565 7 0.024
regionalization GO:0003002 274 0.024
regulation of protein transport GO:0051223 3 0.024
chordate embryonic development GO:0043009 271 0.024
regulation of multicellular organismal development GO:2000026 223 0.024
response to chemical GO:0042221 320 0.024
regulation of synapse assembly GO:0051963 3 0.024
regulation of response to stimulus GO:0048583 269 0.024
negative regulation of protein phosphorylation GO:0001933 4 0.024
rna biosynthetic process GO:0032774 181 0.024
regulation of cellular amino acid metabolic process GO:0006521 0 0.024
guanosine containing compound catabolic process GO:1901069 2 0.024
regulation of reproductive process GO:2000241 4 0.024
organelle assembly GO:0070925 110 0.023
Worm
response to abiotic stimulus GO:0009628 122 0.023
phagocytosis GO:0006909 3 0.023
peptidyl serine phosphorylation GO:0018105 1 0.023
regulation of protein ubiquitination GO:0031396 3 0.023
digestive tract morphogenesis GO:0048546 231 0.023
gtp catabolic process GO:0006184 2 0.023
taxis GO:0042330 109 0.023
embryo development ending in birth or egg hatching GO:0009792 271 0.023
establishment of protein localization to organelle GO:0072594 4 0.022
positive regulation of catabolic process GO:0009896 4 0.022
positive regulation of transport GO:0051050 2 0.022
regulation of multicellular organism growth GO:0040014 4 0.021
multicellular organism growth GO:0035264 4 0.021
sensory perception of smell GO:0007608 2 0.021
behavior GO:0007610 74 0.021
Worm
cellular response to external stimulus GO:0071496 2 0.021
striated muscle cell development GO:0055002 108 0.021
Worm
development of primary female sexual characteristics GO:0046545 4 0.021
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.021
regulation of cell development GO:0060284 100 0.021
transcription from rna polymerase ii promoter GO:0006366 80 0.021
regulation of establishment of protein localization GO:0070201 4 0.021
regulation of metal ion transport GO:0010959 4 0.021
axonogenesis GO:0007409 152 0.021
regulation of transcription from rna polymerase ii promoter GO:0006357 114 0.020
growth GO:0040007 174 0.020
heart morphogenesis GO:0003007 156 0.020
response to monosaccharide GO:0034284 3 0.020
nuclear import GO:0051170 3 0.020
regulation of purine nucleotide catabolic process GO:0033121 2 0.020
negative regulation of protein kinase activity GO:0006469 4 0.020
regulation of dna replication GO:0006275 3 0.020
immune system process GO:0002376 241 0.020
protein import into nucleus GO:0006606 3 0.020
epithelial tube morphogenesis GO:0060562 148 0.020
embryonic heart tube development GO:0035050 133 0.020
cellular protein modification process GO:0006464 100 0.020
eye morphogenesis GO:0048592 144 0.019
protein modification process GO:0036211 100 0.019
camera type eye development GO:0043010 222 0.019
autophagy GO:0006914 4 0.019
morphogenesis of an epithelial sheet GO:0002011 49 0.019
cell substrate junction assembly GO:0007044 2 0.019
protein localization to nucleus GO:0034504 3 0.019
single organism nuclear import GO:1902593 3 0.019
regulation of cytokine production GO:0001817 3 0.019
dorsal ventral pattern formation GO:0009953 125 0.019
positive regulation of cellular amine metabolic process GO:0033240 0 0.019
retina development in camera type eye GO:0060041 146 0.019
centrosome organization GO:0051297 1 0.019
protein targeting to nucleus GO:0044744 3 0.019
microtubule organizing center organization GO:0031023 1 0.019
aromatic compound biosynthetic process GO:0019438 217 0.019
neuromuscular synaptic transmission GO:0007274 2 0.019
axon guidance GO:0007411 86 0.019
gland development GO:0048732 143 0.019
female gonad development GO:0008585 4 0.019
cell death GO:0008219 121 0.019
cellular amide metabolic process GO:0043603 4 0.019
neuroblast proliferation GO:0007405 2 0.018
lateral inhibition GO:0046331 1 0.018
cellular ketone metabolic process GO:0042180 11 0.018
regulation of circadian rhythm GO:0042752 4 0.018
germ line stem cell maintenance GO:0030718 2 0.018
gastrulation GO:0007369 208 0.018
regulation of neuron projection development GO:0010975 40 0.018
cellular protein metabolic process GO:0044267 129 0.018
sensory perception of chemical stimulus GO:0007606 3 0.018
water homeostasis GO:0030104 4 0.018
cellular localization GO:0051641 97 0.018
regulation of synapse organization GO:0050807 3 0.018
regulation of dendrite development GO:0050773 3 0.018
positive regulation of cell cycle GO:0045787 3 0.018
organonitrogen compound metabolic process GO:1901564 74 0.018
regulation of nucleoside metabolic process GO:0009118 2 0.018
camera type eye morphogenesis GO:0048593 108 0.018
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.018
regulation of ion transmembrane transporter activity GO:0032412 2 0.017
regulation of binding GO:0051098 3 0.017
carboxylic acid metabolic process GO:0019752 22 0.017
cell substrate adhesion GO:0031589 4 0.017
cell fate commitment GO:0045165 99 0.017
regulation of calcium ion transport GO:0051924 2 0.017
apoptotic process GO:0006915 116 0.017
synaptic transmission GO:0007268 35 0.017
Worm
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.017
cell projection assembly GO:0030031 64 0.017
regulation of synaptic plasticity GO:0048167 1 0.017
exocytosis GO:0006887 1 0.017
skeletal system morphogenesis GO:0048705 102 0.017
regulation of blood pressure GO:0008217 1 0.016
regulation of protein complex assembly GO:0043254 3 0.016
oxoacid metabolic process GO:0043436 31 0.016
retina morphogenesis in camera type eye GO:0060042 79 0.016
embryonic cranial skeleton morphogenesis GO:0048701 90 0.016
chemosensory behavior GO:0007635 1 0.016
negative regulation of kinase activity GO:0033673 4 0.016
centrosome cycle GO:0007098 1 0.016
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.016
sensory organ morphogenesis GO:0090596 200 0.016
regulation of nucleotide catabolic process GO:0030811 2 0.016
embryonic viscerocranium morphogenesis GO:0048703 52 0.016
embryonic heart tube morphogenesis GO:0003143 108 0.016
blood vessel development GO:0001568 246 0.016
positive regulation of cellular component biogenesis GO:0044089 3 0.016
response to organic substance GO:0010033 153 0.016
phagocytosis engulfment GO:0006911 1 0.016
striated muscle cell differentiation GO:0051146 129 0.016
Worm
ear development GO:0043583 127 0.015
positive regulation of extrinsic apoptotic signaling pathway GO:2001238 1 0.015
regulation of neurotransmitter transport GO:0051588 1 0.015
regulation of protein import into nucleus GO:0042306 2 0.015
ameboidal type cell migration GO:0001667 143 0.015
regulation of localization GO:0032879 104 0.015
determination of heart left right asymmetry GO:0061371 117 0.015
cell surface receptor signaling pathway GO:0007166 325 0.015
chemotaxis GO:0006935 104 0.015
homeostatic process GO:0042592 142 0.015
Worm
regulation of organ growth GO:0046620 3 0.015
wnt signaling pathway GO:0016055 80 0.015
cellular protein catabolic process GO:0044257 4 0.015
forebrain development GO:0030900 96 0.015
positive regulation of rna biosynthetic process GO:1902680 57 0.015
regulation of neurotransmitter secretion GO:0046928 1 0.015
regulation of protein modification by small protein conjugation or removal GO:1903320 3 0.015
lipid storage GO:0019915 1 0.015
renal system development GO:0072001 94 0.015
membrane invagination GO:0010324 1 0.015
regulation of cytoplasmic transport GO:1903649 4 0.015
mitochondrion organization GO:0007005 4 0.014
regulation of programmed cell death GO:0043067 101 0.014
positive regulation of metabolic process GO:0009893 108 0.014
hemopoiesis GO:0030097 183 0.014
spermatid development GO:0007286 2 0.014
positive regulation of nucleoside metabolic process GO:0045979 1 0.014
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.014
cellular component assembly GO:0022607 170 0.014
Worm
actin cytoskeleton organization GO:0030036 63 0.014
Worm
regulation of intracellular protein transport GO:0033157 3 0.014
embryonic skeletal system development GO:0048706 97 0.014
organic acid metabolic process GO:0006082 31 0.014
mesenchyme development GO:0060485 127 0.014
small molecule metabolic process GO:0044281 77 0.014
stem cell development GO:0048864 82 0.014
extrinsic apoptotic signaling pathway GO:0097191 3 0.014
cellular response to chemical stimulus GO:0070887 157 0.014
regulation of extrinsic apoptotic signaling pathway GO:2001236 3 0.014
cellular amino acid metabolic process GO:0006520 7 0.014
skeletal system development GO:0001501 181 0.014
organelle localization GO:0051640 49 0.014
cellular response to extracellular stimulus GO:0031668 2 0.014
programmed cell death GO:0012501 119 0.014
cilium organization GO:0044782 71 0.014
regulation of gtpase activity GO:0043087 2 0.014
cell cycle GO:0007049 93 0.014
modification dependent macromolecule catabolic process GO:0043632 3 0.014
startle response GO:0001964 4 0.014
pancreas development GO:0031016 84 0.014
regulation of nucleocytoplasmic transport GO:0046822 2 0.014
regulation of cell motility GO:2000145 46 0.014
fin development GO:0033333 77 0.014
negative regulation of macromolecule metabolic process GO:0010605 76 0.014
cilium morphogenesis GO:0060271 85 0.014
notochord development GO:0030903 54 0.013
skeletal muscle organ development GO:0060538 78 0.013
regulation of nervous system development GO:0051960 90 0.013
regulation of apoptotic process GO:0042981 98 0.013
purine ribonucleoside monophosphate catabolic process GO:0009169 4 0.013
neuron projection guidance GO:0097485 86 0.013
immune system development GO:0002520 191 0.013
regulation of protein localization to nucleus GO:1900180 2 0.013
macromolecule modification GO:0043412 111 0.013
locomotor rhythm GO:0045475 3 0.013
positive regulation of purine nucleotide catabolic process GO:0033123 1 0.013
kidney development GO:0001822 92 0.013
protein homooligomerization GO:0051260 3 0.013
positive regulation of macromolecule metabolic process GO:0010604 93 0.013
establishment of vesicle localization GO:0051650 24 0.013
vasculature development GO:0001944 278 0.013
liver development GO:0001889 96 0.013
antimicrobial humoral response GO:0019730 2 0.013
response to carbohydrate GO:0009743 3 0.013
positive regulation of cellular catabolic process GO:0031331 3 0.013
regulation of gtp catabolic process GO:0033124 2 0.013
cilium assembly GO:0042384 58 0.013
monoamine transport GO:0015844 1 0.013
appendage development GO:0048736 80 0.013
phosphate containing compound metabolic process GO:0006796 108 0.013
negative regulation of nitrogen compound metabolic process GO:0051172 59 0.012
myofibril assembly GO:0030239 48 0.012
Worm
heart looping GO:0001947 94 0.012
ubiquitin dependent protein catabolic process GO:0006511 3 0.012
intracellular signal transduction GO:0035556 85 0.012
regulation of dendrite morphogenesis GO:0048814 3 0.012
connective tissue development GO:0061448 99 0.012
regulation of transmembrane transporter activity GO:0022898 2 0.012
response to alkaloid GO:0043279 2 0.012
establishment of synaptic vesicle localization GO:0097480 1 0.012
modification dependent protein catabolic process GO:0019941 3 0.012
regulation of cell communication GO:0010646 232 0.012
Worm
positive regulation of map kinase activity GO:0043406 3 0.012
peripheral nervous system development GO:0007422 55 0.012
convergent extension GO:0060026 118 0.012
positive regulation of apoptotic signaling pathway GO:2001235 1 0.012
outflow tract morphogenesis GO:0003151 1 0.012
ribonucleoside monophosphate catabolic process GO:0009158 4 0.012
cellular response to radiation GO:0071478 4 0.012
negative regulation of protein serine threonine kinase activity GO:0071901 2 0.012
positive regulation of nucleotide catabolic process GO:0030813 1 0.012
regulation of cellular component organization GO:0051128 86 0.012
positive regulation of secretion GO:0051047 1 0.012
hematopoietic or lymphoid organ development GO:0048534 191 0.012
peptide transport GO:0015833 1 0.012
nucleoside monophosphate catabolic process GO:0009125 4 0.012
phosphorus metabolic process GO:0006793 109 0.012
actin filament based process GO:0030029 64 0.012
Worm
cellular response to hypoxia GO:0071456 1 0.012
negative regulation of metabolic process GO:0009892 86 0.012
epidermal cell fate specification GO:0009957 4 0.012
negative regulation of signal transduction GO:0009968 94 0.012
developmental growth GO:0048589 166 0.012
regulation of transporter activity GO:0032409 2 0.012
cellular component disassembly GO:0022411 1 0.011
regulation of protein catabolic process GO:0042176 1 0.011
sleep GO:0030431 1 0.011
positive regulation of gtp catabolic process GO:0033126 1 0.011
meiotic nuclear division GO:0007126 4 0.011
positive regulation of cell adhesion GO:0045785 1 0.011
regulation of cell morphogenesis GO:0022604 42 0.011
peptidyl serine modification GO:0018209 2 0.011
regulation of locomotion GO:0040012 55 0.011
Worm
positive regulation of cellular metabolic process GO:0031325 94 0.011
regulation of stem cell proliferation GO:0072091 2 0.011
synaptic vesicle localization GO:0097479 1 0.011
b cell activation GO:0042113 2 0.011
negative regulation of dna replication GO:0008156 2 0.011
hormone secretion GO:0046879 2 0.011
tissue remodeling GO:0048771 4 0.011
myeloid cell differentiation GO:0030099 86 0.011
regulation of sequestering of calcium ion GO:0051282 4 0.011
negative regulation of mapk cascade GO:0043409 4 0.011
developmental growth involved in morphogenesis GO:0060560 86 0.011
hepaticobiliary system development GO:0061008 98 0.011
cell migration involved in gastrulation GO:0042074 79 0.011
cell cell signaling GO:0007267 52 0.011
Worm
stem cell division GO:0017145 1 0.011
epithelial cell differentiation GO:0030855 116 0.011
response to oxygen containing compound GO:1901700 55 0.011
regulation of muscle contraction GO:0006937 3 0.011
positive regulation of secretion by cell GO:1903532 1 0.011
multi organism process GO:0051704 134 0.011
regulation of reactive oxygen species metabolic process GO:2000377 2 0.011
positive regulation of gtpase activity GO:0043547 1 0.011
inner ear development GO:0048839 126 0.011
regulation of i kappab kinase nf kappab signaling GO:0043122 4 0.011
negative regulation of gliogenesis GO:0014014 1 0.010
regulation of protein binding GO:0043393 3 0.010
somatic stem cell maintenance GO:0035019 1 0.010
negative regulation of dna metabolic process GO:0051053 4 0.010
regulation of membrane potential GO:0042391 23 0.010
macromolecular complex subunit organization GO:0043933 74 0.010
protein secretion GO:0009306 1 0.010
urogenital system development GO:0001655 97 0.010
negative regulation of transcription dna templated GO:0045892 45 0.010
regulation of cellular component movement GO:0051270 55 0.010
negative regulation of cell differentiation GO:0045596 46 0.010
response to wounding GO:0009611 116 0.010
purine nucleoside monophosphate catabolic process GO:0009128 4 0.010
glucose homeostasis GO:0042593 1 0.010
pectoral fin development GO:0033339 50 0.010
exocrine system development GO:0035272 28 0.010
regulation of epithelial cell proliferation GO:0050678 3 0.010
regulation of jak stat cascade GO:0046425 3 0.010
cytoskeleton organization GO:0007010 96 0.010
Worm
skeletal muscle tissue development GO:0007519 67 0.010
sensory perception of pain GO:0019233 1 0.010
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 68 0.010
embryonic skeletal system morphogenesis GO:0048704 93 0.010
protein polymerization GO:0051258 4 0.010
nuclear export GO:0051168 1 0.010
positive regulation of peptidyl tyrosine phosphorylation GO:0050731 1 0.010
carbohydrate homeostasis GO:0033500 1 0.010
proteasomal protein catabolic process GO:0010498 2 0.010
catecholamine metabolic process GO:0006584 2 0.010
negative regulation of intracellular transport GO:0032387 3 0.010

dtna disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.024
nervous system disease DOID:863 0 0.016
disease of metabolism DOID:0014667 0 0.012
musculoskeletal system disease DOID:17 0 0.012
disease of cellular proliferation DOID:14566 0 0.011