|
|
signal transduction
|
GO:0007165 |
455 |
0.981
|
|
|
|
regulation of primary metabolic process
|
GO:0080090 |
311 |
0.955
|
Human Mouse |
|
|
cell surface receptor signaling pathway
|
GO:0007166 |
325 |
0.953
|
|
|
|
tube morphogenesis
|
GO:0035239 |
349 |
0.947
|
|
|
|
regulation of macromolecule metabolic process
|
GO:0060255 |
317 |
0.946
|
Human Mouse |
|
|
regulation of cell communication
|
GO:0010646 |
232 |
0.942
|
|
|
|
regionalization
|
GO:0003002 |
274 |
0.939
|
|
|
|
regulation of developmental process
|
GO:0050793 |
247 |
0.927
|
|
|
|
cellular aromatic compound metabolic process
|
GO:0006725 |
295 |
0.919
|
|
|
|
nitrogen compound metabolic process
|
GO:0006807 |
319 |
0.890
|
|
|
|
regulation of cell differentiation
|
GO:0045595 |
142 |
0.887
|
|
|
|
cellular component movement
|
GO:0006928 |
335 |
0.878
|
|
|
|
regulation of signal transduction
|
GO:0009966 |
225 |
0.865
|
|
|
|
regulation of response to stimulus
|
GO:0048583 |
269 |
0.858
|
|
|
|
embryonic organ development
|
GO:0048568 |
381 |
0.852
|
|
|
|
cell part morphogenesis
|
GO:0032990 |
246 |
0.851
|
|
|
|
nucleobase containing compound metabolic process
|
GO:0006139 |
274 |
0.849
|
|
|
|
renal system development
|
GO:0072001 |
94 |
0.838
|
|
|
|
regulation of signaling
|
GO:0023051 |
235 |
0.830
|
|
|
|
regulation of macromolecule biosynthetic process
|
GO:0010556 |
225 |
0.812
|
|
|
|
locomotion
|
GO:0040011 |
313 |
0.809
|
|
|
|
head development
|
GO:0060322 |
303 |
0.798
|
|
|
|
response to organic substance
|
GO:0010033 |
153 |
0.798
|
|
|
|
positive regulation of cellular process
|
GO:0048522 |
201 |
0.798
|
Human |
|
|
epithelial tube morphogenesis
|
GO:0060562 |
148 |
0.777
|
Fly |
|
|
regulation of cellular metabolic process
|
GO:0031323 |
320 |
0.771
|
Human Mouse Fly |
|
|
kidney development
|
GO:0001822 |
92 |
0.756
|
|
|
|
regulation of gene expression
|
GO:0010468 |
265 |
0.745
|
|
|
|
cellular nitrogen compound metabolic process
|
GO:0034641 |
290 |
0.745
|
|
|
|
negative regulation of phosphate metabolic process
|
GO:0045936 |
13 |
0.738
|
Human Mouse Fly |
|
|
neuron differentiation
|
GO:0030182 |
353 |
0.736
|
|
|
|
regulation of cell fate commitment
|
GO:0010453 |
22 |
0.733
|
|
|
|
central nervous system development
|
GO:0007417 |
387 |
0.725
|
|
|
|
reproductive process
|
GO:0022414 |
40 |
0.723
|
|
|
|
hematopoietic or lymphoid organ development
|
GO:0048534 |
191 |
0.722
|
|
|
|
gene expression
|
GO:0010467 |
252 |
0.718
|
|
|
|
protein modification process
|
GO:0036211 |
100 |
0.712
|
|
|
|
sensory organ development
|
GO:0007423 |
393 |
0.709
|
|
|
|
endoderm formation
|
GO:0001706 |
29 |
0.689
|
|
|
|
embryonic organ morphogenesis
|
GO:0048562 |
274 |
0.685
|
|
|
|
endodermal cell fate specification
|
GO:0001714 |
17 |
0.680
|
|
|
|
regulation of transcription from rna polymerase ii promoter
|
GO:0006357 |
114 |
0.677
|
|
|
|
response to external stimulus
|
GO:0009605 |
264 |
0.665
|
|
|
|
regulation of transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0090092 |
50 |
0.664
|
|
|
|
dorsal ventral pattern formation
|
GO:0009953 |
125 |
0.663
|
|
|
|
enzyme linked receptor protein signaling pathway
|
GO:0007167 |
106 |
0.661
|
|
|
|
cell projection morphogenesis
|
GO:0048858 |
244 |
0.654
|
|
|
|
morphogenesis of an epithelium
|
GO:0002009 |
333 |
0.653
|
Fly |
|
|
localization of cell
|
GO:0051674 |
244 |
0.653
|
|
|
|
cell projection organization
|
GO:0030030 |
284 |
0.648
|
|
|
|
transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0007178 |
68 |
0.640
|
|
|
|
transcription dna templated
|
GO:0006351 |
181 |
0.639
|
|
|
|
cell morphogenesis involved in differentiation
|
GO:0000904 |
195 |
0.626
|
|
|
|
wnt signaling pathway
|
GO:0016055 |
80 |
0.620
|
|
|
|
stem cell maintenance
|
GO:0019827 |
4 |
0.619
|
|
|
|
cell motility
|
GO:0048870 |
244 |
0.605
|
|
|
|
homeostatic process
|
GO:0042592 |
142 |
0.603
|
Fly |
|
|
cell fate specification
|
GO:0001708 |
68 |
0.601
|
|
|
|
rna metabolic process
|
GO:0016070 |
219 |
0.599
|
|
|
|
hypothalamus cell differentiation
|
GO:0021979 |
4 |
0.591
|
|
|
|
cellular response to chemical stimulus
|
GO:0070887 |
157 |
0.587
|
|
|
|
neuron projection morphogenesis
|
GO:0048812 |
161 |
0.587
|
|
|
|
cellular macromolecule biosynthetic process
|
GO:0034645 |
224 |
0.566
|
|
|
|
regulation of phosphorus metabolic process
|
GO:0051174 |
43 |
0.564
|
Human Mouse Fly |
|
|
negative regulation of nucleobase containing compound metabolic process
|
GO:0045934 |
59 |
0.564
|
|
|
|
heterocycle metabolic process
|
GO:0046483 |
290 |
0.562
|
|
|
|
macromolecule biosynthetic process
|
GO:0009059 |
227 |
0.557
|
|
|
|
negative regulation of cellular process
|
GO:0048523 |
283 |
0.555
|
Human Mouse Fly |
|
|
negative regulation of gene expression
|
GO:0010629 |
65 |
0.555
|
|
|
|
brain development
|
GO:0007420 |
293 |
0.554
|
|
|
|
nucleic acid metabolic process
|
GO:0090304 |
244 |
0.553
|
|
|
|
regulation of cell cycle
|
GO:0051726 |
52 |
0.552
|
|
|
|
positive regulation of nucleobase containing compound metabolic process
|
GO:0045935 |
69 |
0.546
|
|
|
|
neuron development
|
GO:0048666 |
262 |
0.544
|
|
|
|
response to chemical
|
GO:0042221 |
320 |
0.539
|
|
|
|
negative regulation of map kinase activity
|
GO:0043407 |
2 |
0.535
|
Human |
|
|
cell fate commitment involved in formation of primary germ layer
|
GO:0060795 |
26 |
0.532
|
|
|
|
aromatic compound biosynthetic process
|
GO:0019438 |
217 |
0.519
|
|
|
|
rna biosynthetic process
|
GO:0032774 |
181 |
0.517
|
|
|
|
taxis
|
GO:0042330 |
109 |
0.516
|
|
|
|
positive regulation of biological process
|
GO:0048518 |
253 |
0.512
|
Human |
|
|
negative regulation of metabolic process
|
GO:0009892 |
86 |
0.506
|
Human Mouse Fly |
|
|
bmp signaling pathway
|
GO:0030509 |
52 |
0.501
|
|
|
|
embryo development ending in birth or egg hatching
|
GO:0009792 |
271 |
0.498
|
|
|
|
single organism metabolic process
|
GO:0044710 |
217 |
0.496
|
Human Fly |
|
|
canonical wnt signaling pathway
|
GO:0060070 |
48 |
0.494
|
|
|
|
cellular macromolecule metabolic process
|
GO:0044260 |
391 |
0.485
|
|
|
|
response to stress
|
GO:0006950 |
263 |
0.483
|
Human |
|
|
cellular component morphogenesis
|
GO:0032989 |
336 |
0.481
|
|
|
|
organic cyclic compound metabolic process
|
GO:1901360 |
301 |
0.480
|
|
|
|
formation of primary germ layer
|
GO:0001704 |
62 |
0.478
|
|
|
|
generation of neurons
|
GO:0048699 |
385 |
0.478
|
|
|
|
stem cell proliferation
|
GO:0072089 |
4 |
0.474
|
|
|
|
protein metabolic process
|
GO:0019538 |
183 |
0.472
|
|
|
|
regulation of cellular response to growth factor stimulus
|
GO:0090287 |
35 |
0.461
|
|
|
|
cell morphogenesis
|
GO:0000902 |
289 |
0.459
|
|
|
|
determination of heart left right asymmetry
|
GO:0061371 |
117 |
0.438
|
|
|
|
mitotic cell cycle
|
GO:0000278 |
64 |
0.438
|
|
|
|
gastrulation with mouth forming second
|
GO:0001702 |
44 |
0.437
|
|
|
|
heterocycle biosynthetic process
|
GO:0018130 |
215 |
0.436
|
|
|
|
regulation of metabolic process
|
GO:0019222 |
359 |
0.435
|
Human Mouse Fly |
|
|
regulation of rna biosynthetic process
|
GO:2001141 |
213 |
0.434
|
|
|
|
endodermal cell differentiation
|
GO:0035987 |
19 |
0.430
|
|
|
|
nucleic acid templated transcription
|
GO:0097659 |
181 |
0.430
|
|
|
|
cell cycle process
|
GO:0022402 |
53 |
0.429
|
|
|
|
cellular protein metabolic process
|
GO:0044267 |
129 |
0.427
|
|
|
|
cell morphogenesis involved in neuron differentiation
|
GO:0048667 |
163 |
0.427
|
|
|
|
regulation of wnt signaling pathway involved in digestive tract morphogenesis
|
GO:2000056 |
2 |
0.426
|
|
|
|
regulation of fibroblast growth factor receptor signaling pathway
|
GO:0040036 |
20 |
0.422
|
|
|
|
single organism transport
|
GO:0044765 |
206 |
0.422
|
|
|
|
phosphorylation
|
GO:0016310 |
69 |
0.414
|
Human Mouse Fly |
|
|
positive regulation of nitrogen compound metabolic process
|
GO:0051173 |
69 |
0.413
|
|
|
|
embryonic limb morphogenesis
|
GO:0030326 |
2 |
0.412
|
|
|
|
negative regulation of response to stimulus
|
GO:0048585 |
104 |
0.404
|
Human Fly |
|
|
phosphorus metabolic process
|
GO:0006793 |
109 |
0.402
|
|
|
|
rhombomere 5 development
|
GO:0021571 |
4 |
0.401
|
|
|
|
positive regulation of canonical wnt signaling pathway
|
GO:0090263 |
4 |
0.400
|
|
|
|
determination of bilateral symmetry
|
GO:0009855 |
204 |
0.399
|
|
|
|
digestive tract morphogenesis
|
GO:0048546 |
231 |
0.398
|
|
|
|
determination of left right symmetry
|
GO:0007368 |
179 |
0.393
|
|
|
|
regulation of wnt signaling pathway
|
GO:0030111 |
53 |
0.392
|
|
|
|
regulation of multicellular organismal process
|
GO:0051239 |
277 |
0.391
|
|
|
|
cell migration
|
GO:0016477 |
237 |
0.390
|
|
|
|
neural tube patterning
|
GO:0021532 |
33 |
0.388
|
|
|
|
negative regulation of macromolecule metabolic process
|
GO:0010605 |
76 |
0.387
|
Human Mouse |
|
|
regulation of nitrogen compound metabolic process
|
GO:0051171 |
251 |
0.387
|
|
|
|
regulation of cell death
|
GO:0010941 |
103 |
0.374
|
Human |
|
|
regulation of cell fate specification
|
GO:0042659 |
20 |
0.373
|
|
|
|
negative regulation of biological process
|
GO:0048519 |
304 |
0.373
|
Human Mouse Fly |
|
|
negative regulation of kinase activity
|
GO:0033673 |
4 |
0.372
|
Human |
|
|
chemical homeostasis
|
GO:0048878 |
49 |
0.367
|
|
|
|
immune system development
|
GO:0002520 |
191 |
0.364
|
|
|
|
mitotic nuclear division
|
GO:0007067 |
18 |
0.363
|
|
|
|
regulation of cellular macromolecule biosynthetic process
|
GO:2000112 |
222 |
0.358
|
|
|
|
regulation of biological quality
|
GO:0065008 |
263 |
0.349
|
Fly |
|
|
negative regulation of cell communication
|
GO:0010648 |
96 |
0.340
|
Human Fly |
|
|
segmentation
|
GO:0035282 |
97 |
0.340
|
|
|
|
response to growth factor
|
GO:0070848 |
39 |
0.340
|
|
|
|
mesenchyme development
|
GO:0060485 |
127 |
0.338
|
|
|
|
urogenital system development
|
GO:0001655 |
97 |
0.336
|
|
|
|
muscle cell differentiation
|
GO:0042692 |
139 |
0.336
|
|
|
|
cell cycle
|
GO:0007049 |
93 |
0.335
|
|
|
|
nucleobase containing compound biosynthetic process
|
GO:0034654 |
205 |
0.333
|
|
|
|
positive regulation of cell communication
|
GO:0010647 |
56 |
0.331
|
|
|
|
organonitrogen compound metabolic process
|
GO:1901564 |
74 |
0.331
|
|
|
|
specification of symmetry
|
GO:0009799 |
204 |
0.328
|
|
|
|
regulation of nucleobase containing compound metabolic process
|
GO:0019219 |
250 |
0.325
|
|
|
|
appendage development
|
GO:0048736 |
80 |
0.320
|
Fly |
|
|
rhombomere formation
|
GO:0021594 |
12 |
0.318
|
|
|
|
gland development
|
GO:0048732 |
143 |
0.318
|
|
|
|
negative regulation of protein kinase activity
|
GO:0006469 |
4 |
0.318
|
Human |
|
|
negative regulation of cellular metabolic process
|
GO:0031324 |
77 |
0.317
|
Human Mouse Fly |
|
|
cellular biosynthetic process
|
GO:0044249 |
286 |
0.316
|
|
|
|
multi organism process
|
GO:0051704 |
134 |
0.315
|
|
|
|
fin regeneration
|
GO:0031101 |
51 |
0.312
|
|
|
|
negative regulation of anterior neural cell fate commitment of the neural plate
|
GO:0022001 |
1 |
0.311
|
|
|
|
chemotaxis
|
GO:0006935 |
104 |
0.310
|
|
|
|
specification of organ identity
|
GO:0010092 |
2 |
0.309
|
|
|
|
sensory organ morphogenesis
|
GO:0090596 |
200 |
0.305
|
|
|
|
wnt signaling pathway involved in somitogenesis
|
GO:0090244 |
2 |
0.301
|
|
|
|
forebrain development
|
GO:0030900 |
96 |
0.300
|
|
|
|
axon development
|
GO:0061564 |
166 |
0.300
|
|
|
|
cell fate commitment
|
GO:0045165 |
99 |
0.299
|
|
|
|
cellular process involved in reproduction in multicellular organism
|
GO:0022412 |
28 |
0.296
|
|
|
|
programmed cell death
|
GO:0012501 |
119 |
0.295
|
Human |
|
|
apoptotic process involved in development
|
GO:1902742 |
2 |
0.295
|
|
|
|
single organism localization
|
GO:1902578 |
225 |
0.293
|
|
|
|
negative regulation of protein serine threonine kinase activity
|
GO:0071901 |
2 |
0.291
|
Human |
|
|
regulation of organ morphogenesis
|
GO:2000027 |
35 |
0.290
|
|
|
|
larval development
|
GO:0002164 |
2 |
0.288
|
|
|
|
nephron morphogenesis
|
GO:0072028 |
2 |
0.283
|
|
|
|
regulation of apoptotic process
|
GO:0042981 |
98 |
0.279
|
Human |
|
|
chordate embryonic development
|
GO:0043009 |
271 |
0.276
|
|
|
|
renal tubule morphogenesis
|
GO:0061333 |
1 |
0.273
|
|
|
|
digestive tract development
|
GO:0048565 |
265 |
0.271
|
|
|
|
negative regulation of protein phosphorylation
|
GO:0001933 |
4 |
0.270
|
Human Mouse |
|
|
regulation of bmp signaling pathway
|
GO:0030510 |
39 |
0.267
|
|
|
|
positive regulation of signal transduction
|
GO:0009967 |
56 |
0.267
|
|
|
|
rostrocaudal neural tube patterning
|
GO:0021903 |
29 |
0.258
|
|
|
|
regulation of endodermal cell fate specification
|
GO:0042663 |
15 |
0.255
|
|
|
|
nuclear division
|
GO:0000280 |
23 |
0.252
|
|
|
|
negative regulation of wnt signaling pathway
|
GO:0030178 |
30 |
0.251
|
|
|
|
heart morphogenesis
|
GO:0003007 |
156 |
0.249
|
|
|
|
mesoderm development
|
GO:0007498 |
88 |
0.245
|
|
|
|
regulation of cell proliferation
|
GO:0042127 |
37 |
0.238
|
Fly |
|
|
apoptotic process
|
GO:0006915 |
116 |
0.236
|
Human |
|
|
diencephalon development
|
GO:0021536 |
58 |
0.235
|
|
|
|
kidney epithelium development
|
GO:0072073 |
23 |
0.235
|
|
|
|
regulation of canonical wnt signaling pathway
|
GO:0060828 |
34 |
0.234
|
|
|
|
ear development
|
GO:0043583 |
127 |
0.233
|
|
|
|
immune system process
|
GO:0002376 |
241 |
0.233
|
Fly |
|
|
negative regulation of transcription from rna polymerase ii promoter
|
GO:0000122 |
16 |
0.232
|
|
|
|
positive regulation of cell differentiation
|
GO:0045597 |
30 |
0.232
|
|
|
|
single organism reproductive process
|
GO:0044702 |
40 |
0.230
|
|
|
|
ameboidal type cell migration
|
GO:0001667 |
143 |
0.230
|
|
|
|
rhombomere 6 development
|
GO:0021572 |
4 |
0.227
|
|
|
|
sexual reproduction
|
GO:0019953 |
36 |
0.226
|
|
|
|
cellular amine metabolic process
|
GO:0044106 |
2 |
0.225
|
|
|
|
negative regulation of biosynthetic process
|
GO:0009890 |
55 |
0.223
|
|
|
|
axonogenesis
|
GO:0007409 |
152 |
0.222
|
|
|
|
positive regulation of cell proliferation
|
GO:0008284 |
15 |
0.219
|
|
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
0 |
0.218
|
|
|
|
amine metabolic process
|
GO:0009308 |
2 |
0.218
|
|
|
|
organophosphate metabolic process
|
GO:0019637 |
37 |
0.212
|
|
|
|
tissue remodeling
|
GO:0048771 |
4 |
0.211
|
|
|
|
nucleocytoplasmic transport
|
GO:0006913 |
4 |
0.210
|
|
|
|
cell surface receptor signaling pathway involved in heart development
|
GO:0061311 |
20 |
0.206
|
|
|
|
muscle tissue development
|
GO:0060537 |
110 |
0.202
|
|
|
|
establishment of localization
|
GO:0051234 |
244 |
0.202
|
|
|
|
adherens junction organization
|
GO:0034332 |
4 |
0.200
|
|
|
|
cellular response to endogenous stimulus
|
GO:0071495 |
68 |
0.193
|
|
|
|
negative regulation of nucleic acid templated transcription
|
GO:1903507 |
45 |
0.190
|
|
|
|
positive regulation of cell cycle
|
GO:0045787 |
3 |
0.189
|
|
|
|
macromolecule modification
|
GO:0043412 |
111 |
0.188
|
|
|
|
small molecule metabolic process
|
GO:0044281 |
77 |
0.188
|
|
|
|
regulation of neuron differentiation
|
GO:0045664 |
56 |
0.187
|
|
|
|
negative regulation of signal transduction
|
GO:0009968 |
94 |
0.186
|
Human Fly |
|
|
embryonic pattern specification
|
GO:0009880 |
44 |
0.185
|
|
|
|
negative regulation of transcription dna templated
|
GO:0045892 |
45 |
0.184
|
|
|
|
cellular localization
|
GO:0051641 |
97 |
0.184
|
|
|
|
liver development
|
GO:0001889 |
96 |
0.184
|
|
|
|
nephron tubule morphogenesis
|
GO:0072078 |
1 |
0.183
|
|
|
|
neuron projection guidance
|
GO:0097485 |
86 |
0.180
|
|
|
|
organic cyclic compound biosynthetic process
|
GO:1901362 |
223 |
0.180
|
|
|
|
segment polarity determination
|
GO:0007367 |
1 |
0.177
|
|
|
|
stem cell differentiation
|
GO:0048863 |
117 |
0.177
|
|
|
|
heart looping
|
GO:0001947 |
94 |
0.175
|
|
|
|
fibroblast growth factor receptor signaling pathway
|
GO:0008543 |
22 |
0.173
|
|
|
|
regulation of cellular biosynthetic process
|
GO:0031326 |
245 |
0.173
|
|
|
|
positive regulation of signaling
|
GO:0023056 |
56 |
0.172
|
|
|
|
muscle organ development
|
GO:0007517 |
101 |
0.170
|
|
|
|
mesoderm formation
|
GO:0001707 |
43 |
0.167
|
|
|
|
regulation of transcription dna templated
|
GO:0006355 |
213 |
0.166
|
|
|
|
bmp signaling pathway involved in heart jogging
|
GO:0003303 |
14 |
0.162
|
|
|
|
regulation of stem cell proliferation
|
GO:0072091 |
2 |
0.161
|
|
|
|
cellular amino acid metabolic process
|
GO:0006520 |
7 |
0.161
|
|
|
|
digestive system development
|
GO:0055123 |
289 |
0.161
|
|
|
|
hemopoiesis
|
GO:0030097 |
183 |
0.160
|
|
|
|
mitotic cell cycle process
|
GO:1903047 |
48 |
0.160
|
|
|
|
death
|
GO:0016265 |
121 |
0.158
|
Human |
|
|
negative regulation of mapk cascade
|
GO:0043409 |
4 |
0.157
|
Human Fly |
|
|
nuclear transport
|
GO:0051169 |
4 |
0.156
|
|
|
|
sensory system development
|
GO:0048880 |
76 |
0.156
|
|
|
|
wnt signaling pathway involved in digestive tract morphogenesis
|
GO:0044333 |
4 |
0.156
|
|
|
|
neural tube development
|
GO:0021915 |
62 |
0.154
|
|
|
|
metal ion homeostasis
|
GO:0055065 |
26 |
0.152
|
|
|
|
biosynthetic process
|
GO:0009058 |
294 |
0.150
|
|
|
|
cell proliferation
|
GO:0008283 |
80 |
0.147
|
Fly |
|
|
developmental growth
|
GO:0048589 |
166 |
0.147
|
Mouse |
|
|
regulation of rna metabolic process
|
GO:0051252 |
224 |
0.146
|
|
|
|
positive regulation of response to stimulus
|
GO:0048584 |
80 |
0.145
|
|
|
|
signal transduction by phosphorylation
|
GO:0023014 |
18 |
0.145
|
Human Fly |
|
|
mesoderm morphogenesis
|
GO:0048332 |
51 |
0.145
|
|
|
|
positive regulation of cellular catabolic process
|
GO:0031331 |
3 |
0.144
|
|
|
|
cellular metal ion homeostasis
|
GO:0006875 |
16 |
0.143
|
|
|
|
oocyte development
|
GO:0048599 |
14 |
0.143
|
|
|
|
cellular protein modification process
|
GO:0006464 |
100 |
0.140
|
|
|
|
hepatocyte proliferation
|
GO:0072574 |
2 |
0.140
|
|
|
|
regulation of cellular component organization
|
GO:0051128 |
86 |
0.140
|
|
|
|
regulation of transcription from rna polymerase ii promoter involved in heart development
|
GO:1901213 |
15 |
0.140
|
|
|
|
nephron epithelium morphogenesis
|
GO:0072088 |
1 |
0.140
|
|
|
|
nephron development
|
GO:0072006 |
31 |
0.139
|
|
|
|
negative regulation of rna metabolic process
|
GO:0051253 |
48 |
0.139
|
|
|
|
negative regulation of macromolecule biosynthetic process
|
GO:0010558 |
48 |
0.138
|
|
|
|
osteoblast differentiation
|
GO:0001649 |
5 |
0.134
|
|
|
|
transport
|
GO:0006810 |
220 |
0.133
|
|
|
|
positive regulation of cellular biosynthetic process
|
GO:0031328 |
68 |
0.131
|
|
|
|
regulation of programmed cell death
|
GO:0043067 |
101 |
0.131
|
Human |
|
|
cell cell signaling
|
GO:0007267 |
52 |
0.131
|
|
|
|
negative regulation of signaling
|
GO:0023057 |
96 |
0.128
|
Human Fly |
|
|
positive regulation of macromolecule biosynthetic process
|
GO:0010557 |
59 |
0.127
|
|
|
|
regulation of biosynthetic process
|
GO:0009889 |
250 |
0.127
|
|
|
|
single organism organelle organization
|
GO:1902589 |
199 |
0.127
|
|
|
|
neuron projection development
|
GO:0031175 |
180 |
0.126
|
|
|
|
epithelial cell proliferation involved in liver morphogenesis
|
GO:0072575 |
2 |
0.124
|
|
|
|
macromolecular complex assembly
|
GO:0065003 |
35 |
0.121
|
|
|
|
apoptotic process involved in morphogenesis
|
GO:0060561 |
2 |
0.120
|
|
|
|
homologous chromosome segregation
|
GO:0045143 |
1 |
0.118
|
|
|
|
regulation of wound healing
|
GO:0061041 |
2 |
0.117
|
|
|
|
blood coagulation
|
GO:0007596 |
12 |
0.117
|
|
|
|
phosphate containing compound metabolic process
|
GO:0006796 |
108 |
0.117
|
|
|
|
response to external biotic stimulus
|
GO:0043207 |
97 |
0.115
|
|
|
|
peptidyl lysine acetylation
|
GO:0018394 |
2 |
0.114
|
|
|
|
negative regulation of axon extension involved in axon guidance
|
GO:0048843 |
1 |
0.113
|
|
|
|
oocyte differentiation
|
GO:0009994 |
14 |
0.111
|
|
|
|
midbrain hindbrain boundary development
|
GO:0030917 |
23 |
0.111
|
|
|
|
protein phosphorylation
|
GO:0006468 |
47 |
0.111
|
Human Mouse |
|
|
regulation of reproductive process
|
GO:2000241 |
4 |
0.111
|
|
|
|
purine containing compound metabolic process
|
GO:0072521 |
29 |
0.110
|
|
|
|
single organismal cell cell adhesion
|
GO:0016337 |
29 |
0.109
|
Fly |
|
|
kupffer s vesicle development
|
GO:0070121 |
50 |
0.109
|
|
|
|
negative regulation of anterior neural cell fate commitment of the neural plate by wnt signaling pathway
|
GO:0022002 |
1 |
0.109
|
|
|
|
multicellular organismal reproductive process
|
GO:0048609 |
35 |
0.108
|
|
|
|
regulation of embryonic development
|
GO:0045995 |
47 |
0.108
|
|
|
|
gliogenesis
|
GO:0042063 |
45 |
0.107
|
|
|
|
midbrain development
|
GO:0030901 |
28 |
0.106
|
|
|
|
anterior posterior pattern specification
|
GO:0009952 |
152 |
0.104
|
|
|
|
nuclear import
|
GO:0051170 |
3 |
0.104
|
|
|
|
cellular response to growth factor stimulus
|
GO:0071363 |
39 |
0.103
|
|
|
|
appendage morphogenesis
|
GO:0035107 |
56 |
0.102
|
Fly |
|
|
negative regulation of cellular macromolecule biosynthetic process
|
GO:2000113 |
48 |
0.101
|
|
|
|
positive regulation of rna metabolic process
|
GO:0051254 |
59 |
0.101
|
|
|
|
gamete generation
|
GO:0007276 |
33 |
0.100
|
|
|
|
inner ear development
|
GO:0048839 |
126 |
0.100
|
|
|
|
regulation of protein binding
|
GO:0043393 |
3 |
0.100
|
|
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
7 |
0.099
|
|
|
|
establishment of protein localization to organelle
|
GO:0072594 |
4 |
0.099
|
|
|
|
negative regulation of cellular biosynthetic process
|
GO:0031327 |
55 |
0.099
|
|
|
|
regeneration
|
GO:0031099 |
91 |
0.098
|
|
|
|
skeletal system morphogenesis
|
GO:0048705 |
102 |
0.097
|
|
|
|
negative regulation of bmp signaling pathway
|
GO:0030514 |
13 |
0.095
|
|
|
|
developmental process involved in reproduction
|
GO:0003006 |
27 |
0.095
|
|
|
|
cartilage development
|
GO:0051216 |
96 |
0.095
|
|
|
|
regulation of cell development
|
GO:0060284 |
100 |
0.094
|
|
|
|
axon guidance
|
GO:0007411 |
86 |
0.094
|
|
|
|
dorsal ventral axis specification
|
GO:0009950 |
14 |
0.094
|
|
|
|
skeletal system development
|
GO:0001501 |
181 |
0.093
|
|
|
|
positive regulation of biosynthetic process
|
GO:0009891 |
68 |
0.093
|
|
|
|
response to wounding
|
GO:0009611 |
116 |
0.093
|
|
|
|
axis specification
|
GO:0009798 |
43 |
0.092
|
|
|
|
intracellular signal transduction
|
GO:0035556 |
85 |
0.092
|
Human Fly |
|
|
cell migration involved in gastrulation
|
GO:0042074 |
79 |
0.091
|
|
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
0 |
0.090
|
|
|
|
positive regulation of stem cell proliferation
|
GO:2000648 |
1 |
0.089
|
|
|
|
regulation of kinase activity
|
GO:0043549 |
15 |
0.088
|
Human |
|
|
multicellular organismal metabolic process
|
GO:0044236 |
2 |
0.087
|
|
|
|
organic acid metabolic process
|
GO:0006082 |
31 |
0.087
|
|
|
|
retinal ganglion cell axon guidance
|
GO:0031290 |
35 |
0.087
|
|
|
|
carboxylic acid metabolic process
|
GO:0019752 |
22 |
0.086
|
|
|
|
microtubule based process
|
GO:0007017 |
60 |
0.086
|
|
|
|
regulation of anatomical structure morphogenesis
|
GO:0022603 |
130 |
0.086
|
|
|
|
protein import into nucleus
|
GO:0006606 |
3 |
0.086
|
|
|
|
ion transport
|
GO:0006811 |
114 |
0.086
|
|
|
|
macromolecular complex subunit organization
|
GO:0043933 |
74 |
0.086
|
|
|
|
cellular response to external stimulus
|
GO:0071496 |
2 |
0.085
|
|
|
|
somite development
|
GO:0061053 |
96 |
0.085
|
|
|
|
endodermal cell fate commitment
|
GO:0001711 |
18 |
0.085
|
|
|
|
cognition
|
GO:0050890 |
1 |
0.085
|
|
|
|
regulation of molecular function
|
GO:0065009 |
70 |
0.084
|
Human |
|
|
gastrulation
|
GO:0007369 |
208 |
0.083
|
|
|
|
cellular response to retinoic acid
|
GO:0071300 |
1 |
0.083
|
|
|
|
negative regulation of developmental process
|
GO:0051093 |
65 |
0.082
|
|
|
|
regulation of gtp catabolic process
|
GO:0033124 |
2 |
0.081
|
|
|
|
regulation of cell migration
|
GO:0030334 |
40 |
0.081
|
|
|
|
multicellular organism growth
|
GO:0035264 |
4 |
0.081
|
|
|
|
striated muscle tissue development
|
GO:0014706 |
110 |
0.081
|
|
|
|
pronephros development
|
GO:0048793 |
69 |
0.080
|
|
|
|
developmental induction
|
GO:0031128 |
10 |
0.079
|
|
|
|
cellular homeostasis
|
GO:0019725 |
26 |
0.079
|
|
|
|
regulation of anterior head development
|
GO:2000742 |
2 |
0.079
|
|
|
|
cell death
|
GO:0008219 |
121 |
0.079
|
Human |
|
|
cellular chemical homeostasis
|
GO:0055082 |
17 |
0.079
|
|
|
|
positive regulation of cell adhesion
|
GO:0045785 |
1 |
0.079
|
|
|
|
protein complex assembly
|
GO:0006461 |
30 |
0.078
|
|
|
|
divalent inorganic cation homeostasis
|
GO:0072507 |
22 |
0.078
|
|
|
|
morphogenesis of a branching structure
|
GO:0001763 |
21 |
0.078
|
Fly |
|
|
regulation of wnt signaling pathway calcium modulating pathway
|
GO:0008591 |
3 |
0.077
|
|
|
|
regulation of apoptotic signaling pathway
|
GO:2001233 |
12 |
0.077
|
|
|
|
kidney morphogenesis
|
GO:0060993 |
15 |
0.077
|
|
|
|
regulation of multicellular organismal development
|
GO:2000026 |
223 |
0.076
|
|
|
|
regulation of catalytic activity
|
GO:0050790 |
55 |
0.076
|
Human |
|
|
regulation of peptidyl tyrosine phosphorylation
|
GO:0050730 |
1 |
0.076
|
|
|
|
regulation of catenin import into nucleus
|
GO:0035412 |
2 |
0.075
|
|
|
|
regulation of phosphorylation
|
GO:0042325 |
26 |
0.075
|
Human Mouse Fly |
|
|
positive regulation of rna biosynthetic process
|
GO:1902680 |
57 |
0.075
|
|
|
|
positive regulation of macromolecule metabolic process
|
GO:0010604 |
93 |
0.075
|
|
|
|
negative regulation of nitrogen compound metabolic process
|
GO:0051172 |
59 |
0.073
|
|
|
|
positive regulation of gene expression
|
GO:0010628 |
71 |
0.072
|
|
|
|
cellular response to nutrient levels
|
GO:0031669 |
2 |
0.071
|
|
|
|
embryonic heart tube development
|
GO:0035050 |
133 |
0.071
|
|
|
|
oogenesis
|
GO:0048477 |
14 |
0.070
|
|
|
|
protein import
|
GO:0017038 |
3 |
0.069
|
|
|
|
regulation of localization
|
GO:0032879 |
104 |
0.069
|
|
|
|
homeostasis of number of cells within a tissue
|
GO:0048873 |
4 |
0.068
|
|
|
|
response to fibroblast growth factor
|
GO:0071774 |
22 |
0.068
|
|
|
|
heart field specification
|
GO:0003128 |
1 |
0.068
|
|
|
|
meiosis i
|
GO:0007127 |
1 |
0.067
|
|
|
|
regulation of cellular protein metabolic process
|
GO:0032268 |
52 |
0.067
|
Human Mouse |
|
|
positive regulation of map kinase activity
|
GO:0043406 |
3 |
0.066
|
|
|
|
hypothalamus development
|
GO:0021854 |
14 |
0.066
|
|
|
|
regulation of response to stress
|
GO:0080134 |
36 |
0.066
|
|
|
|
activation of jun kinase activity
|
GO:0007257 |
2 |
0.066
|
|
|
|
regulation of protein metabolic process
|
GO:0051246 |
56 |
0.066
|
Human Mouse |
|
|
regulation of neurogenesis
|
GO:0050767 |
87 |
0.065
|
|
|
|
peptidyl amino acid modification
|
GO:0018193 |
16 |
0.065
|
|
|
|
regulation of cytoskeleton organization
|
GO:0051493 |
11 |
0.065
|
|
|
|
regulation of binding
|
GO:0051098 |
3 |
0.065
|
|
|
|
germ cell development
|
GO:0007281 |
22 |
0.065
|
|
|
|
divalent metal ion transport
|
GO:0070838 |
20 |
0.064
|
|
|
|
cellular response to starvation
|
GO:0009267 |
1 |
0.064
|
|
|
|
cellular response to organic substance
|
GO:0071310 |
105 |
0.064
|
|
|
|
positive regulation of striated muscle cell differentiation
|
GO:0051155 |
1 |
0.062
|
|
|
|
morphogenesis of a branching epithelium
|
GO:0061138 |
16 |
0.061
|
Fly |
|
|
female gamete generation
|
GO:0007292 |
14 |
0.061
|
|
|
|
odontogenesis of dentin containing tooth
|
GO:0042475 |
1 |
0.061
|
|
|
|
negative regulation of stem cell differentiation
|
GO:2000737 |
2 |
0.060
|
|
|
|
regulation of locomotion
|
GO:0040012 |
55 |
0.060
|
|
|
|
divalent inorganic cation transport
|
GO:0072511 |
21 |
0.060
|
|
|
|
embryonic heart tube morphogenesis
|
GO:0003143 |
108 |
0.060
|
|
|
|
vesicle mediated transport
|
GO:0016192 |
22 |
0.060
|
|
|
|
regulation of chronic inflammatory response
|
GO:0002676 |
1 |
0.059
|
|
|
|
regulation of phosphate metabolic process
|
GO:0019220 |
43 |
0.059
|
Human Mouse Fly |
|
|
regulation of cell motility
|
GO:2000145 |
46 |
0.059
|
|
|
|
negative regulation of phosphorylation
|
GO:0042326 |
6 |
0.058
|
Human Mouse Fly |
|
|
periodic partitioning
|
GO:0007365 |
1 |
0.058
|
|
|
|
positive regulation of immune effector process
|
GO:0002699 |
3 |
0.058
|
|
|
|
regulation of i kappab kinase nf kappab signaling
|
GO:0043122 |
4 |
0.057
|
|
|
|
reproduction
|
GO:0000003 |
40 |
0.057
|
|
|
|
anterior head development
|
GO:0097065 |
2 |
0.057
|
|
|
|
negative regulation of cell fate commitment
|
GO:0010454 |
13 |
0.057
|
|
|
|
coagulation
|
GO:0050817 |
13 |
0.056
|
|
|
|
spindle assembly
|
GO:0051225 |
2 |
0.056
|
|
|
|
mononuclear cell proliferation
|
GO:0032943 |
1 |
0.055
|
|
|
|
regulation of stem cell differentiation
|
GO:2000736 |
4 |
0.054
|
|
|
|
wound healing
|
GO:0042060 |
90 |
0.054
|
|
|
|
positive regulation of metabolic process
|
GO:0009893 |
108 |
0.054
|
|
|
|
cellular response to extracellular stimulus
|
GO:0031668 |
2 |
0.054
|
|
|
|
intracellular transport
|
GO:0046907 |
32 |
0.053
|
|
|
|
sensory perception
|
GO:0007600 |
39 |
0.053
|
|
|
|
microtubule organizing center organization
|
GO:0031023 |
1 |
0.053
|
|
|
|
mesodermal cell differentiation
|
GO:0048333 |
21 |
0.052
|
|
|
|
striated muscle cell differentiation
|
GO:0051146 |
129 |
0.052
|
|
|
|
multicellular organism reproduction
|
GO:0032504 |
35 |
0.052
|
|
|
|
regulation of mesenchymal cell proliferation
|
GO:0010464 |
1 |
0.052
|
|
|
|
gtp metabolic process
|
GO:0046039 |
4 |
0.052
|
|
|
|
cellular response to dna damage stimulus
|
GO:0006974 |
24 |
0.052
|
|
|
|
developmental maturation
|
GO:0021700 |
34 |
0.051
|
|
|
|
regulation of ossification
|
GO:0030278 |
5 |
0.051
|
|
|
|
oxoacid metabolic process
|
GO:0043436 |
31 |
0.051
|
|
|
|
myotube cell development
|
GO:0014904 |
35 |
0.051
|
|
|
|
transcription from rna polymerase ii promoter
|
GO:0006366 |
80 |
0.051
|
|
|
|
negative regulation of cell fate specification
|
GO:0009996 |
11 |
0.050
|
|
|
|
positive regulation of catabolic process
|
GO:0009896 |
4 |
0.050
|
|
|
|
epithelial tube formation
|
GO:0072175 |
19 |
0.050
|
|
|
|
regulation of syncytium formation by plasma membrane fusion
|
GO:0060142 |
2 |
0.050
|
|
|
|
ossification
|
GO:0001503 |
23 |
0.049
|
|
|
|
spemann organizer formation
|
GO:0060061 |
10 |
0.049
|
|
|
|
regulation of transport
|
GO:0051049 |
45 |
0.049
|
|
|
|
positive regulation of neurogenesis
|
GO:0050769 |
24 |
0.048
|
|
|
|
transmembrane receptor protein tyrosine kinase signaling pathway
|
GO:0007169 |
42 |
0.048
|
|
|
|
multi organism reproductive process
|
GO:0044703 |
36 |
0.048
|
|
|
|
lipid metabolic process
|
GO:0006629 |
52 |
0.048
|
|
|
|
calcium ion transport into cytosol
|
GO:0060402 |
3 |
0.047
|
|
|
|
mesenchymal cell development
|
GO:0014031 |
78 |
0.047
|
|
|
|
positive regulation of transcription dna templated
|
GO:0045893 |
57 |
0.047
|
|
|
|
limb development
|
GO:0060173 |
8 |
0.047
|
|
|
|
regulation of metal ion transport
|
GO:0010959 |
4 |
0.046
|
|
|
|
positive regulation of developmental process
|
GO:0051094 |
50 |
0.046
|
|
|
|
extrinsic apoptotic signaling pathway
|
GO:0097191 |
3 |
0.046
|
|
|
|
connective tissue development
|
GO:0061448 |
99 |
0.046
|
|
|
|
regulation of protein kinase activity
|
GO:0045859 |
15 |
0.045
|
Human |
|
|
regulation of gastrulation
|
GO:0010470 |
24 |
0.045
|
|
|
|
regulation of extrinsic apoptotic signaling pathway in absence of ligand
|
GO:2001239 |
1 |
0.044
|
|
|
|
regulation of gtpase activity
|
GO:0043087 |
2 |
0.044
|
|
|
|
stem cell development
|
GO:0048864 |
82 |
0.043
|
|
|
|
regulation of endodermal cell differentiation
|
GO:1903224 |
15 |
0.043
|
|
|
|
regulation of nucleic acid templated transcription
|
GO:1903506 |
213 |
0.043
|
|
|
|
organelle assembly
|
GO:0070925 |
110 |
0.043
|
|
|
|
thrombocyte differentiation
|
GO:0002574 |
4 |
0.043
|
|
|
|
cellular ketone metabolic process
|
GO:0042180 |
11 |
0.043
|
|
|
|
regulation of protein modification process
|
GO:0031399 |
29 |
0.043
|
Human Mouse |
|
|
positive regulation of bmp signaling pathway
|
GO:0030513 |
10 |
0.042
|
|
|
|
negative chemotaxis
|
GO:0050919 |
1 |
0.042
|
|
|
|
tube closure
|
GO:0060606 |
1 |
0.042
|
|
|
|
system process
|
GO:0003008 |
185 |
0.041
|
|
|
|
cell cycle g1 s phase transition
|
GO:0044843 |
1 |
0.041
|
|
|
|
bone mineralization
|
GO:0030282 |
9 |
0.041
|
|
|
|
protein acylation
|
GO:0043543 |
3 |
0.041
|
|
|
|
growth
|
GO:0040007 |
174 |
0.041
|
Mouse |
|
|
cell cell signaling involved in cell fate commitment
|
GO:0045168 |
12 |
0.040
|
|
|
|
limb morphogenesis
|
GO:0035108 |
7 |
0.040
|
|
|
|
photoreceptor cell differentiation
|
GO:0046530 |
55 |
0.040
|
|
|
|
defense response to other organism
|
GO:0098542 |
33 |
0.040
|
|
|
|
regulation of neural precursor cell proliferation
|
GO:2000177 |
3 |
0.040
|
|
|
|
positive regulation of cellular amino acid metabolic process
|
GO:0045764 |
0 |
0.040
|
|
|
|
regulation of cell cycle process
|
GO:0010564 |
20 |
0.040
|
|
|
|
regulation of epithelial to mesenchymal transition
|
GO:0010717 |
3 |
0.039
|
|
|
|
cellular component biogenesis
|
GO:0044085 |
178 |
0.039
|
|
|
|
extrinsic apoptotic signaling pathway in absence of ligand
|
GO:0097192 |
1 |
0.039
|
|
|
|
single organism nuclear import
|
GO:1902593 |
3 |
0.039
|
|
|
|
embryonic skeletal system development
|
GO:0048706 |
97 |
0.039
|
|
|
|
regulation of mesodermal cell fate specification
|
GO:0042661 |
9 |
0.039
|
|
|
|
regulation of organelle organization
|
GO:0033043 |
29 |
0.039
|
|
|
|
regulation of muscle organ development
|
GO:0048634 |
9 |
0.039
|
|
|
|
determination of dorsal ventral asymmetry
|
GO:0048262 |
34 |
0.039
|
|
|
|
regulation of transferase activity
|
GO:0051338 |
16 |
0.038
|
Human |
|
|
single organism cell adhesion
|
GO:0098602 |
29 |
0.038
|
Fly |
|
|
cell division
|
GO:0051301 |
20 |
0.038
|
|
|
|
establishment of localization in cell
|
GO:0051649 |
77 |
0.038
|
|
|
|
spinal cord anterior posterior patterning
|
GO:0021512 |
1 |
0.038
|
|
