|
|
positive regulation of jun kinase activity
|
GO:0043507 |
2 |
0.391
|
Human |
|
|
positive regulation of map kinase activity
|
GO:0043406 |
3 |
0.320
|
Human |
|
|
cellular nitrogen compound metabolic process
|
GO:0034641 |
290 |
0.277
|
Human |
|
|
nucleobase containing compound metabolic process
|
GO:0006139 |
274 |
0.268
|
Human |
|
|
larval development
|
GO:0002164 |
2 |
0.263
|
Worm |
|
|
regulation of nucleobase containing compound metabolic process
|
GO:0019219 |
250 |
0.248
|
Human |
|
|
organic cyclic compound biosynthetic process
|
GO:1901362 |
223 |
0.204
|
Human |
|
|
nitrogen compound metabolic process
|
GO:0006807 |
319 |
0.192
|
Human |
|
|
embryo development ending in birth or egg hatching
|
GO:0009792 |
271 |
0.191
|
Worm Fly |
|
|
regulation of macromolecule metabolic process
|
GO:0060255 |
317 |
0.180
|
Human Worm |
|
|
nucleic acid metabolic process
|
GO:0090304 |
244 |
0.174
|
Human |
|
|
sensory organ development
|
GO:0007423 |
393 |
0.169
|
Fly |
|
|
regulation of cellular biosynthetic process
|
GO:0031326 |
245 |
0.167
|
Human |
|
|
microtubule based process
|
GO:0007017 |
60 |
0.167
|
Worm |
|
|
positive regulation of jnk cascade
|
GO:0046330 |
3 |
0.156
|
Human |
|
|
positive regulation of stress activated protein kinase signaling cascade
|
GO:0070304 |
3 |
0.154
|
Human |
|
|
heterocycle biosynthetic process
|
GO:0018130 |
215 |
0.153
|
Human |
|
|
cellular nitrogen compound biosynthetic process
|
GO:0044271 |
218 |
0.152
|
Human |
|
|
negative regulation of stem cell differentiation
|
GO:2000737 |
2 |
0.146
|
Fly |
|
|
positive regulation of stress activated mapk cascade
|
GO:0032874 |
3 |
0.135
|
Human |
|
|
aromatic compound biosynthetic process
|
GO:0019438 |
217 |
0.135
|
Human |
|
|
proteasomal protein catabolic process
|
GO:0010498 |
2 |
0.131
|
|
|
|
modification dependent protein catabolic process
|
GO:0019941 |
3 |
0.129
|
|
|
|
cellular aromatic compound metabolic process
|
GO:0006725 |
295 |
0.125
|
Human |
|
|
neuron projection development
|
GO:0031175 |
180 |
0.119
|
Fly |
|
|
rna metabolic process
|
GO:0016070 |
219 |
0.115
|
Human |
|
|
regulation of signaling
|
GO:0023051 |
235 |
0.113
|
Human Fly |
|
|
taxis
|
GO:0042330 |
109 |
0.111
|
Fly |
|
|
regulation of biosynthetic process
|
GO:0009889 |
250 |
0.111
|
Human |
|
|
establishment of epithelial cell polarity
|
GO:0090162 |
2 |
0.107
|
Fly |
|
|
cellular component morphogenesis
|
GO:0032989 |
336 |
0.107
|
Fly |
|
|
cell fate commitment
|
GO:0045165 |
99 |
0.104
|
Worm Fly |
|
|
regulation of primary metabolic process
|
GO:0080090 |
311 |
0.101
|
Human |
|
|
regulation of cellular macromolecule biosynthetic process
|
GO:2000112 |
222 |
0.099
|
Human |
|
|
camera type eye development
|
GO:0043010 |
222 |
0.099
|
|
|
|
cell part morphogenesis
|
GO:0032990 |
246 |
0.095
|
Fly |
|
|
regulation of cell communication
|
GO:0010646 |
232 |
0.095
|
Human Fly |
|
|
cellular macromolecule biosynthetic process
|
GO:0034645 |
224 |
0.093
|
Human |
|
|
cellular response to external stimulus
|
GO:0071496 |
2 |
0.093
|
|
|
|
nucleic acid templated transcription
|
GO:0097659 |
181 |
0.092
|
Human |
|
|
rna biosynthetic process
|
GO:0032774 |
181 |
0.092
|
Human |
|
|
negative regulation of cellular process
|
GO:0048523 |
283 |
0.091
|
Fly |
|
|
regulation of nitrogen compound metabolic process
|
GO:0051171 |
251 |
0.090
|
Human |
|
|
organic cyclic compound metabolic process
|
GO:1901360 |
301 |
0.087
|
Human |
|
|
cellular macromolecule metabolic process
|
GO:0044260 |
391 |
0.086
|
Human |
|
|
negative regulation of sequence specific dna binding transcription factor activity
|
GO:0043433 |
2 |
0.084
|
|
|
|
extrinsic apoptotic signaling pathway
|
GO:0097191 |
3 |
0.084
|
|
|
|
transcription dna templated
|
GO:0006351 |
181 |
0.084
|
Human |
|
|
positive regulation of metabolic process
|
GO:0009893 |
108 |
0.082
|
Human |
|
|
protein metabolic process
|
GO:0019538 |
183 |
0.082
|
Human |
|
|
macroautophagy
|
GO:0016236 |
1 |
0.081
|
|
|
|
response to chemical
|
GO:0042221 |
320 |
0.080
|
Fly |
|
|
heterocycle metabolic process
|
GO:0046483 |
290 |
0.075
|
Human |
|
|
regulation of response to cytokine stimulus
|
GO:0060759 |
3 |
0.074
|
|
|
|
response to stress
|
GO:0006950 |
263 |
0.074
|
Human |
|
|
gland development
|
GO:0048732 |
143 |
0.073
|
Fly |
|
|
regulation of cytokine production
|
GO:0001817 |
3 |
0.072
|
|
|
|
locomotion
|
GO:0040011 |
313 |
0.071
|
Zebrafish Worm Fly |
|
|
synaptic target recognition
|
GO:0008039 |
1 |
0.069
|
Fly |
|
|
negative regulation of biological process
|
GO:0048519 |
304 |
0.069
|
Fly |
|
|
cellular response to extracellular stimulus
|
GO:0031668 |
2 |
0.069
|
|
|
|
response to other organism
|
GO:0051707 |
97 |
0.069
|
|
|
|
regulation of response to stimulus
|
GO:0048583 |
269 |
0.068
|
Human Fly |
|
|
cell projection morphogenesis
|
GO:0048858 |
244 |
0.068
|
Fly |
|
|
cellular response to nutrient levels
|
GO:0031669 |
2 |
0.068
|
|
|
|
negative regulation of cytokine production
|
GO:0001818 |
1 |
0.067
|
|
|
|
regulation of protein catabolic process
|
GO:0042176 |
1 |
0.066
|
|
|
|
gene expression
|
GO:0010467 |
252 |
0.064
|
Human |
|
|
positive regulation of transport
|
GO:0051050 |
2 |
0.064
|
|
|
|
regulation of alternative mrna splicing via spliceosome
|
GO:0000381 |
1 |
0.064
|
|
|
|
negative regulation of response to cytokine stimulus
|
GO:0060761 |
2 |
0.064
|
|
|
|
proteasome mediated ubiquitin dependent protein catabolic process
|
GO:0043161 |
2 |
0.064
|
|
|
|
regulation of metabolic process
|
GO:0019222 |
359 |
0.064
|
Human Worm |
|
|
positive regulation of catabolic process
|
GO:0009896 |
4 |
0.062
|
|
|
|
regulation of macromolecule biosynthetic process
|
GO:0010556 |
225 |
0.062
|
Human |
|
|
proteolysis involved in cellular protein catabolic process
|
GO:0051603 |
3 |
0.062
|
|
|
|
cell surface receptor signaling pathway
|
GO:0007166 |
325 |
0.060
|
|
|
|
sensory organ morphogenesis
|
GO:0090596 |
200 |
0.060
|
Fly |
|
|
regulation of rna metabolic process
|
GO:0051252 |
224 |
0.060
|
Human |
|
|
response to external stimulus
|
GO:0009605 |
264 |
0.059
|
Fly |
|
|
single organism localization
|
GO:1902578 |
225 |
0.059
|
Worm |
|
|
generation of neurons
|
GO:0048699 |
385 |
0.058
|
Worm Fly |
|
|
negative regulation of gene expression
|
GO:0010629 |
65 |
0.058
|
|
|
|
nuclear transport
|
GO:0051169 |
4 |
0.058
|
|
|
|
cellular response to starvation
|
GO:0009267 |
1 |
0.058
|
|
|
|
response to biotic stimulus
|
GO:0009607 |
97 |
0.057
|
|
|
|
regulation of cellular metabolic process
|
GO:0031323 |
320 |
0.057
|
Human |
|
|
regulation of mrna splicing via spliceosome
|
GO:0048024 |
3 |
0.057
|
|
|
|
organic substance biosynthetic process
|
GO:1901576 |
289 |
0.055
|
Human |
|
|
somatic stem cell maintenance
|
GO:0035019 |
1 |
0.055
|
Fly |
|
|
cellular component movement
|
GO:0006928 |
335 |
0.054
|
Zebrafish Worm Fly |
|
|
embryonic organ morphogenesis
|
GO:0048562 |
274 |
0.054
|
|
|
|
positive regulation of biological process
|
GO:0048518 |
253 |
0.053
|
Human Fly |
|
|
positive regulation of cell communication
|
GO:0010647 |
56 |
0.052
|
Human |
|
|
chordate embryonic development
|
GO:0043009 |
271 |
0.050
|
|
|
|
organelle organization
|
GO:0006996 |
227 |
0.050
|
Worm Fly |
|
|
negative regulation of cytokine mediated signaling pathway
|
GO:0001960 |
2 |
0.050
|
|
|
|
single organism metabolic process
|
GO:0044710 |
217 |
0.050
|
Human |
|
|
regulation of gene expression
|
GO:0010468 |
265 |
0.050
|
Human Worm |
|
|
brain development
|
GO:0007420 |
293 |
0.050
|
Zebrafish |
|
|
smoothened signaling pathway
|
GO:0007224 |
30 |
0.049
|
|
|
|
stem cell development
|
GO:0048864 |
82 |
0.049
|
Fly |
|
|
establishment of localization
|
GO:0051234 |
244 |
0.049
|
Worm |
|
|
digestive tract morphogenesis
|
GO:0048546 |
231 |
0.049
|
Worm |
|
|
regulation of peptidyl tyrosine phosphorylation
|
GO:0050730 |
1 |
0.048
|
|
|
|
cellular biosynthetic process
|
GO:0044249 |
286 |
0.048
|
Human |
|
|
stem cell maintenance
|
GO:0019827 |
4 |
0.047
|
Fly |
|
|
regulation of meiotic cell cycle
|
GO:0051445 |
1 |
0.047
|
|
|
|
positive regulation of cellular catabolic process
|
GO:0031331 |
3 |
0.047
|
|
|
|
positive regulation of cellular amino acid metabolic process
|
GO:0045764 |
0 |
0.047
|
|
|
|
small molecule metabolic process
|
GO:0044281 |
77 |
0.046
|
|
|
|
maintenance of location
|
GO:0051235 |
4 |
0.046
|
|
|
|
negative chemotaxis
|
GO:0050919 |
1 |
0.046
|
Fly |
|
|
lateral inhibition
|
GO:0046331 |
1 |
0.045
|
|
|
|
negative regulation of nucleobase containing compound metabolic process
|
GO:0045934 |
59 |
0.045
|
|
|
|
negative regulation of nitrogen compound metabolic process
|
GO:0051172 |
59 |
0.045
|
|
|
|
regulation of smoothened signaling pathway
|
GO:0008589 |
18 |
0.045
|
|
|
|
embryonic organ development
|
GO:0048568 |
381 |
0.045
|
|
|
|
regulation of molecular function
|
GO:0065009 |
70 |
0.044
|
Human |
|
|
single organism organelle organization
|
GO:1902589 |
199 |
0.044
|
Worm Fly |
|
|
negative regulation of cellular biosynthetic process
|
GO:0031327 |
55 |
0.044
|
|
|
|
neuron projection morphogenesis
|
GO:0048812 |
161 |
0.044
|
Fly |
|
|
regulation of response to nutrient levels
|
GO:0032107 |
1 |
0.043
|
|
|
|
regulation of cellular component organization
|
GO:0051128 |
86 |
0.043
|
Worm Fly |
|
|
regulation of nucleic acid templated transcription
|
GO:1903506 |
213 |
0.043
|
Human |
|
|
cell migration
|
GO:0016477 |
237 |
0.042
|
Zebrafish Worm Fly |
|
|
regulation of stem cell differentiation
|
GO:2000736 |
4 |
0.042
|
Fly |
|
|
neuron projection guidance
|
GO:0097485 |
86 |
0.042
|
Fly |
|
|
regulation of proteolysis involved in cellular protein catabolic process
|
GO:1903050 |
1 |
0.042
|
|
|
|
positive regulation of cellular amine metabolic process
|
GO:0033240 |
0 |
0.042
|
|
|
|
positive regulation of molecular function
|
GO:0044093 |
33 |
0.042
|
Human |
|
|
immune response
|
GO:0006955 |
28 |
0.041
|
|
|
|
tube morphogenesis
|
GO:0035239 |
349 |
0.041
|
Worm |
|
|
cell projection organization
|
GO:0030030 |
284 |
0.040
|
Fly |
|
|
eye development
|
GO:0001654 |
277 |
0.040
|
Fly |
|
|
head development
|
GO:0060322 |
303 |
0.040
|
Zebrafish |
|
|
response to nutrient
|
GO:0007584 |
3 |
0.039
|
|
|
|
organonitrogen compound metabolic process
|
GO:1901564 |
74 |
0.039
|
|
|
|
positive regulation of cellular process
|
GO:0048522 |
201 |
0.039
|
Human |
|
|
cytoskeleton organization
|
GO:0007010 |
96 |
0.039
|
Worm Fly |
|
|
activation of mapk activity
|
GO:0000187 |
3 |
0.039
|
|
|
|
regulation of organelle assembly
|
GO:1902115 |
4 |
0.038
|
|
|
|
enzyme linked receptor protein signaling pathway
|
GO:0007167 |
106 |
0.038
|
|
|
|
central nervous system development
|
GO:0007417 |
387 |
0.037
|
Zebrafish |
|
|
cellular protein catabolic process
|
GO:0044257 |
4 |
0.036
|
|
|
|
aging
|
GO:0007568 |
2 |
0.036
|
|
|
|
ubiquitin dependent protein catabolic process
|
GO:0006511 |
3 |
0.035
|
|
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
0 |
0.035
|
|
|
|
transcription from rna polymerase ii promoter
|
GO:0006366 |
80 |
0.035
|
|
|
|
immune system process
|
GO:0002376 |
241 |
0.035
|
|
|
|
regulation of transcription dna templated
|
GO:0006355 |
213 |
0.035
|
Human |
|
|
positive regulation of cellular biosynthetic process
|
GO:0031328 |
68 |
0.035
|
Human |
|
|
positive regulation of nucleobase containing compound metabolic process
|
GO:0045935 |
69 |
0.035
|
Human |
|
|
positive regulation of response to stimulus
|
GO:0048584 |
80 |
0.034
|
Human |
|
|
outflow tract morphogenesis
|
GO:0003151 |
1 |
0.034
|
|
|
|
meiotic nuclear division
|
GO:0007126 |
4 |
0.034
|
|
|
|
regulation of binding
|
GO:0051098 |
3 |
0.034
|
|
|
|
cellular response to chemical stimulus
|
GO:0070887 |
157 |
0.034
|
|
|
|
cellular response to stress
|
GO:0033554 |
62 |
0.033
|
Human |
|
|
cell morphogenesis
|
GO:0000902 |
289 |
0.033
|
Fly |
|
|
regulation of cellular protein catabolic process
|
GO:1903362 |
1 |
0.033
|
|
|
|
response to oxidative stress
|
GO:0006979 |
11 |
0.033
|
|
|
|
protein targeting to nucleus
|
GO:0044744 |
3 |
0.033
|
|
|
|
lipid storage
|
GO:0019915 |
1 |
0.032
|
|
|
|
modification dependent macromolecule catabolic process
|
GO:0043632 |
3 |
0.032
|
|
|
|
establishment of monopolar cell polarity
|
GO:0061162 |
2 |
0.031
|
Fly |
|
|
autophagy
|
GO:0006914 |
4 |
0.031
|
|
|
|
cell projection assembly
|
GO:0030031 |
64 |
0.031
|
Fly |
|
|
ameboidal type cell migration
|
GO:0001667 |
143 |
0.031
|
Fly |
|
|
negative regulation of biosynthetic process
|
GO:0009890 |
55 |
0.031
|
|
|
|
axon guidance
|
GO:0007411 |
86 |
0.031
|
Fly |
|
|
mesenchymal cell development
|
GO:0014031 |
78 |
0.030
|
|
|
|
positive regulation of biosynthetic process
|
GO:0009891 |
68 |
0.030
|
Human |
|
|
cellular pigmentation
|
GO:0033059 |
30 |
0.030
|
|
|
|
phagocytosis
|
GO:0006909 |
3 |
0.029
|
|
|
|
regulation of extrinsic apoptotic signaling pathway
|
GO:2001236 |
3 |
0.029
|
|
|
|
developmental growth involved in morphogenesis
|
GO:0060560 |
86 |
0.029
|
|
|
|
cellular ketone metabolic process
|
GO:0042180 |
11 |
0.029
|
|
|
|
positive regulation of apoptotic signaling pathway
|
GO:2001235 |
1 |
0.029
|
|
|
|
regulation of proteolysis
|
GO:0030162 |
24 |
0.029
|
|
|
|
heart morphogenesis
|
GO:0003007 |
156 |
0.028
|
Fly |
|
|
regulation of developmental process
|
GO:0050793 |
247 |
0.028
|
Human Worm Fly |
|
|
cellular amine metabolic process
|
GO:0044106 |
2 |
0.028
|
|
|
|
regulation of cell fate commitment
|
GO:0010453 |
22 |
0.028
|
Fly |
|
|
negative regulation of chromosome organization
|
GO:2001251 |
1 |
0.028
|
|
|
|
neuron differentiation
|
GO:0030182 |
353 |
0.028
|
Fly |
|
|
amine metabolic process
|
GO:0009308 |
2 |
0.028
|
|
|
|
organic acid metabolic process
|
GO:0006082 |
31 |
0.027
|
|
|
|
response to drug
|
GO:0042493 |
3 |
0.027
|
|
|
|
formation of primary germ layer
|
GO:0001704 |
62 |
0.027
|
Worm |
|
|
regulation of cytokine mediated signaling pathway
|
GO:0001959 |
3 |
0.027
|
|
|
|
cellular localization
|
GO:0051641 |
97 |
0.027
|
Worm |
|
|
establishment of apical basal cell polarity
|
GO:0035089 |
2 |
0.027
|
Fly |
|
|
regulation of response to extracellular stimulus
|
GO:0032104 |
1 |
0.027
|
|
|
|
microtubule cytoskeleton organization
|
GO:0000226 |
33 |
0.027
|
Worm |
|
|
segmentation
|
GO:0035282 |
97 |
0.027
|
Fly |
|
|
negative regulation of cellular catabolic process
|
GO:0031330 |
3 |
0.027
|
|
|
|
sex determination
|
GO:0007530 |
1 |
0.026
|
|
|
|
axon development
|
GO:0061564 |
166 |
0.026
|
Fly |
|
|
skin development
|
GO:0043588 |
54 |
0.026
|
Worm Fly |
|
|
regulation of microtubule cytoskeleton organization
|
GO:0070507 |
3 |
0.026
|
Worm |
|
|
regulation of cell cycle
|
GO:0051726 |
52 |
0.026
|
Worm |
|
|
specification of organ identity
|
GO:0010092 |
2 |
0.026
|
|
|
|
cardiac cell fate commitment
|
GO:0060911 |
1 |
0.026
|
Fly |
|
|
positive regulation of dna metabolic process
|
GO:0051054 |
1 |
0.026
|
|
|
|
behavior
|
GO:0007610 |
74 |
0.026
|
Worm |
|
|
cell substrate adhesion
|
GO:0031589 |
4 |
0.026
|
|
|
|
negative regulation of cellular metabolic process
|
GO:0031324 |
77 |
0.026
|
|
|
|
cellular protein modification process
|
GO:0006464 |
100 |
0.026
|
Human |
|
|
signal transduction
|
GO:0007165 |
455 |
0.026
|
|
|
|
heart development
|
GO:0007507 |
313 |
0.026
|
Fly |
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
7 |
0.025
|
|
|
|
positive regulation of peptidyl tyrosine phosphorylation
|
GO:0050731 |
1 |
0.025
|
|
|
|
regulation of signal transduction
|
GO:0009966 |
225 |
0.025
|
Human Fly |
|
|
negative regulation of metabolic process
|
GO:0009892 |
86 |
0.025
|
|
|
|
negative regulation of defense response
|
GO:0031348 |
2 |
0.025
|
|
|
|
cell morphogenesis involved in neuron differentiation
|
GO:0048667 |
163 |
0.025
|
Fly |
|
|
hindbrain development
|
GO:0030902 |
91 |
0.025
|
Zebrafish |
|
|
axonogenesis
|
GO:0007409 |
152 |
0.024
|
Fly |
|
|
regulation of biological quality
|
GO:0065008 |
263 |
0.024
|
Fly |
|
|
female sex differentiation
|
GO:0046660 |
4 |
0.024
|
Fly |
|
|
positive regulation of signal transduction
|
GO:0009967 |
56 |
0.024
|
Human |
|
|
protein localization to nucleus
|
GO:0034504 |
3 |
0.024
|
|
|
|
macromolecule biosynthetic process
|
GO:0009059 |
227 |
0.024
|
Human |
|
|
atp catabolic process
|
GO:0006200 |
4 |
0.024
|
|
|
|
epithelial tube morphogenesis
|
GO:0060562 |
148 |
0.024
|
|
|
|
regulation of immune system process
|
GO:0002682 |
34 |
0.023
|
|
|
|
single organism nuclear import
|
GO:1902593 |
3 |
0.023
|
|
|
|
peptide metabolic process
|
GO:0006518 |
1 |
0.023
|
|
|
|
oxoacid metabolic process
|
GO:0043436 |
31 |
0.023
|
|
|
|
nucleobase containing compound biosynthetic process
|
GO:0034654 |
205 |
0.023
|
Human |
|
|
convergent extension
|
GO:0060026 |
118 |
0.023
|
|
|
|
nuclear export
|
GO:0051168 |
1 |
0.023
|
|
|
|
positive regulation of nitrogen compound metabolic process
|
GO:0051173 |
69 |
0.023
|
Human |
|
|
negative regulation of catabolic process
|
GO:0009895 |
3 |
0.023
|
|
|
|
negative regulation of innate immune response
|
GO:0045824 |
2 |
0.023
|
|
|
|
positive regulation of macromolecule metabolic process
|
GO:0010604 |
93 |
0.023
|
Human |
|
|
chemotaxis
|
GO:0006935 |
104 |
0.023
|
Fly |
|
|
regulation of multicellular organism growth
|
GO:0040014 |
4 |
0.022
|
|
|
|
regulation of rna biosynthetic process
|
GO:2001141 |
213 |
0.022
|
Human |
|
|
regulation of sequence specific dna binding transcription factor activity
|
GO:0051090 |
9 |
0.022
|
|
|
|
ribonucleoside monophosphate catabolic process
|
GO:0009158 |
4 |
0.022
|
|
|
|
negative regulation of signal transduction
|
GO:0009968 |
94 |
0.022
|
Fly |
|
|
gastrulation
|
GO:0007369 |
208 |
0.022
|
Worm |
|
|
heart formation
|
GO:0060914 |
13 |
0.022
|
Fly |
|
|
cellular amino acid metabolic process
|
GO:0006520 |
7 |
0.022
|
|
|
|
biosynthetic process
|
GO:0009058 |
294 |
0.021
|
Human |
|
|
negative regulation of nucleic acid templated transcription
|
GO:1903507 |
45 |
0.021
|
|
|
|
negative regulation of macromolecule metabolic process
|
GO:0010605 |
76 |
0.021
|
|
|
|
response to external biotic stimulus
|
GO:0043207 |
97 |
0.021
|
|
|
|
programmed cell death
|
GO:0012501 |
119 |
0.021
|
|
|
|
positive regulation of signaling
|
GO:0023056 |
56 |
0.021
|
Human |
|
|
lamellipodium assembly
|
GO:0030032 |
1 |
0.021
|
Fly |
|
|
phosphate containing compound metabolic process
|
GO:0006796 |
108 |
0.021
|
Human |
|
|
transport
|
GO:0006810 |
220 |
0.021
|
|
|
|
regulation of synapse assembly
|
GO:0051963 |
3 |
0.021
|
|
|
|
digestive system development
|
GO:0055123 |
289 |
0.021
|
Worm |
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
0 |
0.021
|
|
|
|
specification of symmetry
|
GO:0009799 |
204 |
0.021
|
|
|
|
establishment or maintenance of epithelial cell apical basal polarity
|
GO:0045197 |
11 |
0.021
|
Fly |
|
|
primary neural tube formation
|
GO:0014020 |
1 |
0.021
|
|
|
|
protein processing
|
GO:0016485 |
12 |
0.021
|
|
|
|
regulation of anatomical structure morphogenesis
|
GO:0022603 |
130 |
0.020
|
Human Worm Fly |
|
|
mitotic g2 m transition checkpoint
|
GO:0044818 |
3 |
0.020
|
|
|
|
developmental growth
|
GO:0048589 |
166 |
0.020
|
|
|
|
multicellular organismal reproductive process
|
GO:0048609 |
35 |
0.020
|
Worm Fly |
|
|
regulation of transcription from rna polymerase ii promoter
|
GO:0006357 |
114 |
0.020
|
|
|
|
cell cycle
|
GO:0007049 |
93 |
0.020
|
Worm |
|
|
tube closure
|
GO:0060606 |
1 |
0.020
|
|
|
|
meiosis i
|
GO:0007127 |
1 |
0.020
|
|
|
|
regulation of multicellular organismal process
|
GO:0051239 |
277 |
0.020
|
Human Worm Fly |
|
|
regulation of establishment of protein localization
|
GO:0070201 |
4 |
0.020
|
|
|
|
telomere organization
|
GO:0032200 |
1 |
0.020
|
|
|
|
regulation of multicellular organismal development
|
GO:2000026 |
223 |
0.020
|
Human Worm Fly |
|
|
positive regulation of cellular metabolic process
|
GO:0031325 |
94 |
0.019
|
Human |
|
|
translational initiation
|
GO:0006413 |
3 |
0.019
|
|
|
|
hepaticobiliary system development
|
GO:0061008 |
98 |
0.019
|
|
|
|
determination of bilateral symmetry
|
GO:0009855 |
204 |
0.019
|
|
|
|
negative regulation of protein processing
|
GO:0010955 |
10 |
0.019
|
|
|
|
multi organism process
|
GO:0051704 |
134 |
0.019
|
Worm Fly |
|
|
regulation of establishment or maintenance of cell polarity
|
GO:0032878 |
2 |
0.019
|
Worm |
|
|
lamellipodium organization
|
GO:0097581 |
1 |
0.019
|
Fly |
|
|
canonical wnt signaling pathway involved in heart development
|
GO:0061316 |
1 |
0.019
|
Fly |
|
|
negative regulation of rna metabolic process
|
GO:0051253 |
48 |
0.019
|
|
|
|
regulation of chromosome segregation
|
GO:0051983 |
1 |
0.019
|
|
|
|
regulation of defense response
|
GO:0031347 |
14 |
0.019
|
|
|
|
cellular amide metabolic process
|
GO:0043603 |
4 |
0.018
|
|
|
|
wnt signaling pathway
|
GO:0016055 |
80 |
0.018
|
|
|
|
positive regulation of rna biosynthetic process
|
GO:1902680 |
57 |
0.018
|
Human |
|
|
neuron projection extension
|
GO:1990138 |
45 |
0.018
|
Fly |
|
|
negative regulation of protein maturation
|
GO:1903318 |
10 |
0.018
|
|
|
|
establishment of cell polarity
|
GO:0030010 |
18 |
0.018
|
Worm Fly |
|
|
cell cycle g1 s phase transition
|
GO:0044843 |
1 |
0.018
|
|
|
|
cell proliferation
|
GO:0008283 |
80 |
0.018
|
|
|
|
neuromuscular synaptic transmission
|
GO:0007274 |
2 |
0.018
|
|
|
|
g1 s transition of mitotic cell cycle
|
GO:0000082 |
1 |
0.018
|
|
|
|
positive regulation of macromolecule biosynthetic process
|
GO:0010557 |
59 |
0.018
|
Human |
|
|
negative regulation of proteolysis
|
GO:0045861 |
10 |
0.018
|
|
|
|
appendage development
|
GO:0048736 |
80 |
0.018
|
Fly |
|
|
nucleocytoplasmic transport
|
GO:0006913 |
4 |
0.018
|
|
|
|
negative regulation of cell communication
|
GO:0010648 |
96 |
0.018
|
Fly |
|
|
antimicrobial humoral response
|
GO:0019730 |
2 |
0.018
|
|
|
|
cell cell signaling involved in cell fate commitment
|
GO:0045168 |
12 |
0.017
|
Fly |
|
|
reactive oxygen species biosynthetic process
|
GO:1903409 |
1 |
0.017
|
|
|
|
photoreceptor cell development
|
GO:0042461 |
40 |
0.017
|
|
|
|
carboxylic acid metabolic process
|
GO:0019752 |
22 |
0.017
|
|
|
|
organelle assembly
|
GO:0070925 |
110 |
0.017
|
|
|
|
alternative mrna splicing via spliceosome
|
GO:0000380 |
1 |
0.017
|
|
|
|
regulation of cell cycle process
|
GO:0010564 |
20 |
0.017
|
Worm |
|
|
cellular response to biotic stimulus
|
GO:0071216 |
3 |
0.017
|
|
|
|
protein modification process
|
GO:0036211 |
100 |
0.017
|
Human |
|
|
membrane invagination
|
GO:0010324 |
1 |
0.017
|
|
|
|
phosphorylation
|
GO:0016310 |
69 |
0.016
|
Human |
|
|
cell division
|
GO:0051301 |
20 |
0.016
|
Worm |
|
|
organonitrogen compound biosynthetic process
|
GO:1901566 |
47 |
0.016
|
|
|
|
positive regulation of secretion
|
GO:0051047 |
1 |
0.016
|
|
|
|
morphogenesis of an epithelium
|
GO:0002009 |
333 |
0.016
|
|
|
|
cell morphogenesis involved in differentiation
|
GO:0000904 |
195 |
0.016
|
Fly |
|
|
regulation of protein maturation
|
GO:1903317 |
10 |
0.016
|
|
|
|
regulation of mrna processing
|
GO:0050684 |
3 |
0.016
|
|
|
|
spindle assembly
|
GO:0051225 |
2 |
0.016
|
|
|
|
digestive tract development
|
GO:0048565 |
265 |
0.016
|
Worm |
|
|
death
|
GO:0016265 |
121 |
0.016
|
|
|
|
negative regulation of transcription dna templated
|
GO:0045892 |
45 |
0.016
|
|
|
|
body morphogenesis
|
GO:0010171 |
16 |
0.016
|
Worm |
|
|
reproduction
|
GO:0000003 |
40 |
0.016
|
Worm Fly |
|
|
negative regulation of multicellular organismal process
|
GO:0051241 |
69 |
0.016
|
Fly |
|
|
negative regulation of rna biosynthetic process
|
GO:1902679 |
45 |
0.016
|
|
|
|
rna processing
|
GO:0006396 |
25 |
0.016
|
|
|
|
stem cell proliferation
|
GO:0072089 |
4 |
0.016
|
|
|
|
protein import
|
GO:0017038 |
3 |
0.016
|
|
|
|
ear development
|
GO:0043583 |
127 |
0.016
|
|
|
|
regulation of photoreceptor cell differentiation
|
GO:0046532 |
2 |
0.016
|
|
|
|
immune effector process
|
GO:0002252 |
23 |
0.016
|
|
|
|
regulation of embryonic development
|
GO:0045995 |
47 |
0.016
|
Fly |
|
|
regulation of autophagy
|
GO:0010506 |
3 |
0.015
|
|
|
|
regulation of protein transport
|
GO:0051223 |
3 |
0.015
|
|
|
|
negative regulation of immune response
|
GO:0050777 |
2 |
0.015
|
|
|
|
response to abiotic stimulus
|
GO:0009628 |
122 |
0.015
|
|
|
|
regulation of cytoplasmic transport
|
GO:1903649 |
4 |
0.015
|
|
|
|
liver development
|
GO:0001889 |
96 |
0.015
|
|
|
|
positive regulation of canonical wnt signaling pathway
|
GO:0090263 |
4 |
0.015
|
|
|
|
multicellular organism growth
|
GO:0035264 |
4 |
0.015
|
|
|
|
regulation of locomotion
|
GO:0040012 |
55 |
0.015
|
|
|
|
centrosome organization
|
GO:0051297 |
1 |
0.015
|
|
|
|
regulation of nucleocytoplasmic transport
|
GO:0046822 |
2 |
0.015
|
|
|
|
development of primary female sexual characteristics
|
GO:0046545 |
4 |
0.015
|
Fly |
|
|
mesenchyme development
|
GO:0060485 |
127 |
0.015
|
|
|
|
neuron development
|
GO:0048666 |
262 |
0.015
|
Fly |
|
|
production of molecular mediator of immune response
|
GO:0002440 |
2 |
0.015
|
|
|
|
regulation of protein processing
|
GO:0070613 |
10 |
0.015
|
|
|
|
single organism biosynthetic process
|
GO:0044711 |
71 |
0.015
|
|
|
|
chromatin organization
|
GO:0006325 |
22 |
0.014
|
|
|
|
cell fate specification
|
GO:0001708 |
68 |
0.014
|
Worm Fly |
|
|
retinal ganglion cell axon guidance
|
GO:0031290 |
35 |
0.014
|
Fly |
|
|
response to organic substance
|
GO:0010033 |
153 |
0.014
|
|
|
|
cellular protein metabolic process
|
GO:0044267 |
129 |
0.014
|
Human |
|
|
macromolecule modification
|
GO:0043412 |
111 |
0.014
|
Human |
|
|
convergent extension involved in organogenesis
|
GO:0060029 |
10 |
0.014
|
|
|
|
negative regulation of sequestering of calcium ion
|
GO:0051283 |
4 |
0.014
|
|
|
|
regulation of type i interferon production
|
GO:0032479 |
2 |
0.014
|
|
|
|
cell migration involved in gastrulation
|
GO:0042074 |
79 |
0.014
|
|
|
|
nucleoside monophosphate catabolic process
|
GO:0009125 |
4 |
0.014
|
|
|
|
endoderm development
|
GO:0007492 |
49 |
0.014
|
Worm |
|
|
cell cycle process
|
GO:0022402 |
53 |
0.014
|
Worm |
|
|
regulation of reproductive process
|
GO:2000241 |
4 |
0.014
|
|
|
|
positive regulation of cellular component biogenesis
|
GO:0044089 |
3 |
0.014
|
|
|
|
innate immune response
|
GO:0045087 |
13 |
0.013
|
|
|
|
regulation of cell fate specification
|
GO:0042659 |
20 |
0.013
|
Fly |
|
|
hypothalamus cell differentiation
|
GO:0021979 |
4 |
0.013
|
|
|
|
pigmentation
|
GO:0043473 |
85 |
0.013
|
Fly |
|
|
lymphocyte proliferation
|
GO:0046651 |
1 |
0.013
|
|
|
|
regulation of protein localization to nucleus
|
GO:1900180 |
2 |
0.013
|
|
|
|
mrna metabolic process
|
GO:0016071 |
20 |
0.013
|
|
|
|
protein polymerization
|
GO:0051258 |
4 |
0.013
|
|
|
|
positive regulation of cell cycle
|
GO:0045787 |
3 |
0.013
|
|
|
|
hormone secretion
|
GO:0046879 |
2 |
0.013
|
|
|
|
vasculature development
|
GO:0001944 |
278 |
0.013
|
|
|
|
regulation of localization
|
GO:0032879 |
104 |
0.013
|
Worm |
|
|
microtubule organizing center organization
|
GO:0031023 |
1 |
0.013
|
|
|
|
regulation of cell activation
|
GO:0050865 |
1 |
0.013
|
|
|
|
blood vessel development
|
GO:0001568 |
246 |
0.013
|
|
|
|
wound healing
|
GO:0042060 |
90 |
0.013
|
|
|
|
regulation of programmed cell death
|
GO:0043067 |
101 |
0.013
|
|
|
|
myeloid cell development
|
GO:0061515 |
32 |
0.013
|
|
|
|
stem cell fate commitment
|
GO:0048865 |
1 |
0.013
|
|
|
|
regulation of cellular component movement
|
GO:0051270 |
55 |
0.013
|
|
|
|
cell migration in hindbrain
|
GO:0021535 |
7 |
0.013
|
Zebrafish |
|
|
cellular response to dna damage stimulus
|
GO:0006974 |
24 |
0.013
|
|
|
|
phagocytosis engulfment
|
GO:0006911 |
1 |
0.013
|
|
|
|
regulation of synapse organization
|
GO:0050807 |
3 |
0.012
|
|
|
|
regionalization
|
GO:0003002 |
274 |
0.012
|
Fly |
|
|
regulation of cellular carbohydrate metabolic process
|
GO:0010675 |
4 |
0.012
|
|
|
|
wnt signaling pathway planar cell polarity pathway
|
GO:0060071 |
4 |
0.012
|
Human Worm |
|
|
localization of cell
|
GO:0051674 |
244 |
0.012
|
Zebrafish Worm Fly |
|
|
regulation of nervous system development
|
GO:0051960 |
90 |
0.012
|
|
|
|
chromatin modification
|
GO:0016568 |
21 |
0.012
|
|
|
|
anterior posterior pattern specification
|
GO:0009952 |
152 |
0.012
|
|
|
|
ear morphogenesis
|
GO:0042471 |
64 |
0.012
|
|
|
|
retina development in camera type eye
|
GO:0060041 |
146 |
0.012
|
|
|
|
motor neuron axon guidance
|
GO:0008045 |
23 |
0.012
|
Fly |
|
|
regulation of protein metabolic process
|
GO:0051246 |
56 |
0.012
|
Human |
|
|
intracellular signal transduction
|
GO:0035556 |
85 |
0.012
|
Human |
|
|
establishment of localization in cell
|
GO:0051649 |
77 |
0.012
|
Worm |
|
|
positive regulation of cytoskeleton organization
|
GO:0051495 |
3 |
0.012
|
|
|
|
somitogenesis
|
GO:0001756 |
87 |
0.012
|
|
|
|
regulation of dendrite morphogenesis
|
GO:0048814 |
3 |
0.012
|
|
|
|
negative regulation of protein phosphorylation
|
GO:0001933 |
4 |
0.012
|
|
|
|
exocrine system development
|
GO:0035272 |
28 |
0.012
|
Fly |
|
|
macromolecular complex subunit organization
|
GO:0043933 |
74 |
0.012
|
Worm Fly |
|
|
determination of left right symmetry
|
GO:0007368 |
179 |
0.012
|
|
|
|
regulation of nuclear division
|
GO:0051783 |
9 |
0.012
|
|
|
|
peptidyl serine modification
|
GO:0018209 |
2 |
0.012
|
|
|
|
regulation of protein binding
|
GO:0043393 |
3 |
0.012
|
|
|
|
canonical wnt signaling pathway
|
GO:0060070 |
48 |
0.012
|
Human Fly |
|
|
axis elongation
|
GO:0003401 |
31 |
0.012
|
|
|
|
phosphatidylinositol mediated signaling
|
GO:0048015 |
2 |
0.012
|
|
|
|
negative regulation of dna metabolic process
|
GO:0051053 |
4 |
0.012
|
|
|
|
positive regulation of cytosolic calcium ion concentration
|
GO:0007204 |
4 |
0.012
|
|
|
|
camera type eye morphogenesis
|
GO:0048593 |
108 |
0.012
|
|
|
|
inner ear development
|
GO:0048839 |
126 |
0.012
|
|
|
|
nuclear envelope organization
|
GO:0006998 |
2 |
0.011
|
|
|
|
embryonic skeletal joint development
|
GO:0072498 |
3 |
0.011
|
|
|
|
fin development
|
GO:0033333 |
77 |
0.011
|
|
|
|
regulation of dendrite development
|
GO:0050773 |
3 |
0.011
|
|
|
|
regulation of cellular protein metabolic process
|
GO:0032268 |
52 |
0.011
|
Human |
|
|
growth
|
GO:0040007 |
174 |
0.011
|
|
|
|
fin regeneration
|
GO:0031101 |
51 |
0.011
|
|
|
|
endodermal cell fate specification
|
GO:0001714 |
17 |
0.011
|
Worm |
|
|
cell cycle checkpoint
|
GO:0000075 |
7 |
0.011
|
|
|
|
negative regulation of response to stimulus
|
GO:0048585 |
104 |
0.011
|
Fly |
|
|
synaptic growth at neuromuscular junction
|
GO:0051124 |
2 |
0.011
|
|
|
|
protein destabilization
|
GO:0031648 |
1 |
0.011
|
|
|
|
response to wounding
|
GO:0009611 |
116 |
0.011
|
|
|
|
stem cell differentiation
|
GO:0048863 |
117 |
0.011
|
Fly |
|
|
mesenchymal cell differentiation
|
GO:0048762 |
87 |
0.011
|
|
|
|
transmembrane receptor protein tyrosine kinase signaling pathway
|
GO:0007169 |
42 |
0.011
|
|
|
|
regulation of cell motility
|
GO:2000145 |
46 |
0.011
|
|
|
|
positive regulation of protein kinase b signaling
|
GO:0051897 |
1 |
0.011
|
|
|
|
cellular response to radiation
|
GO:0071478 |
4 |
0.011
|
|
|
|
mitotic cell cycle
|
GO:0000278 |
64 |
0.011
|
Worm |
|
|
negative regulation of immune system process
|
GO:0002683 |
7 |
0.011
|
|
|
|
hormone transport
|
GO:0009914 |
2 |
0.011
|
|
|
|
purine ribonucleoside monophosphate catabolic process
|
GO:0009169 |
4 |
0.011
|
|
|
|
lipid metabolic process
|
GO:0006629 |
52 |
0.011
|
|
|
|
erk1 and erk2 cascade
|
GO:0070371 |
4 |
0.011
|
|
|
|
regulation of cellular response to stress
|
GO:0080135 |
20 |
0.011
|
Human |
|
|
axon extension
|
GO:0048675 |
45 |
0.011
|
Fly |
|
|
stem cell division
|
GO:0017145 |
1 |
0.011
|
|
|
|
eye morphogenesis
|
GO:0048592 |
144 |
0.011
|
Fly |
|
|
nuclear import
|
GO:0051170 |
3 |
0.011
|
|
|
|
dorsal ventral pattern formation
|
GO:0009953 |
125 |
0.011
|
|
|
|
negative regulation of type i interferon mediated signaling pathway
|
GO:0060339 |
1 |
0.011
|
|
|
|
protein import into nucleus
|
GO:0006606 |
3 |
0.011
|
|
|
|
positive regulation of nucleic acid templated transcription
|
GO:1903508 |
57 |
0.011
|
Human |
|
|
positive regulation of protein complex assembly
|
GO:0031334 |
2 |
0.011
|
|
|
|
rna 3 end processing
|
GO:0031123 |
2 |
0.011
|
|
|
|
protein maturation
|
GO:0051604 |
12 |
0.011
|
|
|
|
photoreceptor cell differentiation
|
GO:0046530 |
55 |
0.011
|
|
|
|
protein homooligomerization
|
GO:0051260 |
3 |
0.011
|
|
|
|
cilium organization
|
GO:0044782 |
71 |
0.011
|
|
|
|
tissue regeneration
|
GO:0042246 |
74 |
0.010
|
|
|
|
negative regulation of cell differentiation
|
GO:0045596 |
46 |
0.010
|
Fly |
|
|
defense response
|
GO:0006952 |
47 |
0.010
|
|
|
|
regulation of organ morphogenesis
|
GO:2000027 |
35 |
0.010
|
Human Worm Fly |
|
|
positive regulation of rna metabolic process
|
GO:0051254 |
59 |
0.010
|
Human |
|
|
rna localization
|
GO:0006403 |
4 |
0.010
|
|
|
|
regulation of dna replication
|
GO:0006275 |
3 |
0.010
|
|
|
|
positive regulation of notch signaling pathway
|
GO:0045747 |
3 |
0.010
|
|
|
|
chemosensory behavior
|
GO:0007635 |
1 |
0.010
|
|
|
|
post anal tail morphogenesis
|
GO:0036342 |
19 |
0.010
|
|
|
|
cell fate commitment involved in formation of primary germ layer
|
GO:0060795 |
26 |
0.010
|
Worm |
|
|
regulation of cell migration
|
GO:0030334 |
40 |
0.010
|
|
|
|
cellular component assembly involved in morphogenesis
|
GO:0010927 |
107 |
0.010
|
|
