Danio rerio

61 known processes

eaf2

ELL associated factor 2

(Aliases: wu:fc43g12,zgc:86600,wu:fb76c01)

eaf2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
regulation of cell communication GO:0010646 232 0.174
lipid storage GO:0019915 1 0.154
Worm
digestive tract morphogenesis GO:0048546 231 0.128
regulation of signaling GO:0023051 235 0.099
heart development GO:0007507 313 0.095
positive regulation of transport GO:0051050 2 0.091
negative regulation of signal transduction GO:0009968 94 0.087
ameboidal type cell migration GO:0001667 143 0.081
aging GO:0007568 2 0.078
cell migration involved in gastrulation GO:0042074 79 0.075
regulation of dna damage response signal transduction by p53 class mediator GO:0043516 4 0.074
developmental growth involved in morphogenesis GO:0060560 86 0.072
signal transduction GO:0007165 455 0.070
establishment of localization in cell GO:0051649 77 0.068
glucose homeostasis GO:0042593 1 0.066
brain development GO:0007420 293 0.064
embryonic organ development GO:0048568 381 0.062
growth GO:0040007 174 0.062
carbohydrate homeostasis GO:0033500 1 0.058
larval development GO:0002164 2 0.057
response to glucose GO:0009749 3 0.056
axis elongation GO:0003401 31 0.055
generation of neurons GO:0048699 385 0.054
cellular response to chemical stimulus GO:0070887 157 0.052
regulation of metabolic process GO:0019222 359 0.052
Mouse
tube morphogenesis GO:0035239 349 0.052
regulation of response to stimulus GO:0048583 269 0.049
cellular response to radiation GO:0071478 4 0.049
single organism transport GO:0044765 206 0.045
homeostatic process GO:0042592 142 0.044
cell death in response to oxidative stress GO:0036473 2 0.044
response to biotic stimulus GO:0009607 97 0.044
cellular transition metal ion homeostasis GO:0046916 3 0.043
heart morphogenesis GO:0003007 156 0.042
immune system process GO:0002376 241 0.040
digestive system development GO:0055123 289 0.039
convergent extension involved in organogenesis GO:0060029 10 0.039
macromolecule biosynthetic process GO:0009059 227 0.038
Mouse
meiotic cell cycle process GO:1903046 3 0.038
establishment of protein localization to organelle GO:0072594 4 0.038
localization of cell GO:0051674 244 0.037
pancreas development GO:0031016 84 0.035
maintenance of location GO:0051235 4 0.034
Worm
regulation of signal transduction by p53 class mediator GO:1901796 9 0.033
regulation of synaptic plasticity GO:0048167 1 0.032
centrosome duplication GO:0051298 1 0.031
single organism metabolic process GO:0044710 217 0.031
defense response to other organism GO:0098542 33 0.031
adult behavior GO:0030534 2 0.031
negative regulation of biological process GO:0048519 304 0.031
Mouse
signal transduction by p53 class mediator GO:0072331 13 0.030
response to chemical GO:0042221 320 0.029
cellular chemical homeostasis GO:0055082 17 0.029
regulation of oxidative stress induced cell death GO:1903201 2 0.029
embryonic organ morphogenesis GO:0048562 274 0.029
cellular component movement GO:0006928 335 0.029
chemical homeostasis GO:0048878 49 0.028
morphogenesis of an epithelial sheet GO:0002011 49 0.028
single organism localization GO:1902578 225 0.028
muscle cell migration GO:0014812 4 0.027
organic acid metabolic process GO:0006082 31 0.027
oxoacid metabolic process GO:0043436 31 0.027
nitrogen compound metabolic process GO:0006807 319 0.026
Mouse
positive regulation of biological process GO:0048518 253 0.026
Mouse
cellular response to nutrient levels GO:0031669 2 0.026
regulation of apoptotic process GO:0042981 98 0.026
regulation of intracellular protein transport GO:0033157 3 0.026
regionalization GO:0003002 274 0.025
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.025
Mouse
microtubule organizing center organization GO:0031023 1 0.025
cellular macromolecule biosynthetic process GO:0034645 224 0.025
Mouse
regulation of cellular response to oxidative stress GO:1900407 2 0.025
regulation of multicellular organism growth GO:0040014 4 0.025
regulation of programmed cell death GO:0043067 101 0.025
epithelial tube morphogenesis GO:0060562 148 0.025
ion transport GO:0006811 114 0.025
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.024
Mouse
hepaticobiliary system development GO:0061008 98 0.024
regulation of autophagy GO:0010506 3 0.024
negative regulation of autophagy GO:0010507 1 0.024
embryonic heart tube morphogenesis GO:0003143 108 0.024
negative regulation of dna replication GO:0008156 2 0.024
regulation of biological quality GO:0065008 263 0.024
Worm
neuroblast fate determination GO:0007400 1 0.024
response to hexose GO:0009746 3 0.023
gastrulation GO:0007369 208 0.023
convergent extension GO:0060026 118 0.023
response to external biotic stimulus GO:0043207 97 0.023
determination of heart left right asymmetry GO:0061371 117 0.023
regulation of biosynthetic process GO:0009889 250 0.023
Mouse
centrosome cycle GO:0007098 1 0.023
determination of left right symmetry GO:0007368 179 0.022
response to drug GO:0042493 3 0.022
behavior GO:0007610 74 0.022
regulation of establishment of protein localization GO:0070201 4 0.022
regulation of dna replication GO:0006275 3 0.021
negative regulation of response to stimulus GO:0048585 104 0.021
regulation of protein transport GO:0051223 3 0.021
locomotion GO:0040011 313 0.021
nuclear transport GO:0051169 4 0.020
response to stress GO:0006950 263 0.020
meiotic nuclear division GO:0007126 4 0.020
negative regulation of cell cycle process GO:0010948 9 0.020
biosynthetic process GO:0009058 294 0.019
Mouse
organic substance biosynthetic process GO:1901576 289 0.019
Mouse
autophagy GO:0006914 4 0.019
response to monosaccharide GO:0034284 3 0.019
positive regulation of apoptotic signaling pathway GO:2001235 1 0.019
positive regulation of map kinase activity GO:0043406 3 0.019
positive regulation of catabolic process GO:0009896 4 0.019
regulation of macromolecule metabolic process GO:0060255 317 0.019
Mouse
regulation of response to oxidative stress GO:1902882 2 0.018
sensory organ development GO:0007423 393 0.018
g1 s transition of mitotic cell cycle GO:0000082 1 0.018
programmed cell death GO:0012501 119 0.018
cellular amine metabolic process GO:0044106 2 0.017
negative regulation of programmed cell death GO:0043069 58 0.017
cellular modified amino acid metabolic process GO:0006575 3 0.017
cell migration GO:0016477 237 0.017
cellular component biogenesis GO:0044085 178 0.017
regulation of signal transduction GO:0009966 225 0.017
regulation of rna metabolic process GO:0051252 224 0.017
Mouse
nucleic acid metabolic process GO:0090304 244 0.017
Mouse
neuron differentiation GO:0030182 353 0.017
lipid localization GO:0010876 11 0.017
Worm
regulation of cellular biosynthetic process GO:0031326 245 0.016
Mouse
cellular response to starvation GO:0009267 1 0.016
negative regulation of signal transduction by p53 class mediator GO:1901797 8 0.016
regulation of cytokine production GO:0001817 3 0.016
regulation of response to stress GO:0080134 36 0.016
cellular macromolecule metabolic process GO:0044260 391 0.016
Mouse
ear development GO:0043583 127 0.016
amine metabolic process GO:0009308 2 0.016
cellular response to light stimulus GO:0071482 4 0.016
regulation of nitrogen compound metabolic process GO:0051171 251 0.016
Mouse
cellular homeostasis GO:0019725 26 0.016
positive regulation of secretion by cell GO:1903532 1 0.016
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.016
Mouse
small molecule metabolic process GO:0044281 77 0.016
response to organic substance GO:0010033 153 0.015
mitochondrion organization GO:0007005 4 0.015
specification of symmetry GO:0009799 204 0.015
carboxylic acid metabolic process GO:0019752 22 0.015
cellular nitrogen compound metabolic process GO:0034641 290 0.015
Mouse
cellular component morphogenesis GO:0032989 336 0.015
negative regulation of catabolic process GO:0009895 3 0.015
female sex differentiation GO:0046660 4 0.015
muscle fiber development GO:0048747 52 0.015
diencephalon development GO:0021536 58 0.015
g protein coupled receptor signaling pathway GO:0007186 74 0.015
stem cell differentiation GO:0048863 117 0.015
embryonic limb morphogenesis GO:0030326 2 0.015
positive regulation of metabolic process GO:0009893 108 0.015
Mouse
negative regulation of cellular catabolic process GO:0031330 3 0.015
sphingolipid biosynthetic process GO:0030148 2 0.014
meiotic spindle organization GO:0000212 1 0.014
recombinational repair GO:0000725 1 0.014
single organism membrane fusion GO:0044801 2 0.014
zinc ion homeostasis GO:0055069 1 0.014
transcription from rna polymerase ii promoter GO:0006366 80 0.014
extrinsic apoptotic signaling pathway GO:0097191 3 0.014
ovarian follicle development GO:0001541 2 0.014
organic cyclic compound biosynthetic process GO:1901362 223 0.014
Mouse
negative regulation of mitosis GO:0045839 3 0.014
glial cell differentiation GO:0010001 42 0.014
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.014
epiboly involved in gastrulation with mouth forming second GO:0055113 35 0.014
myeloid cell homeostasis GO:0002262 56 0.014
positive regulation of cytosolic calcium ion concentration GO:0007204 4 0.014
organonitrogen compound metabolic process GO:1901564 74 0.014
mitotic dna integrity checkpoint GO:0044774 4 0.014
transport GO:0006810 220 0.014
regulation of transcription from rna polymerase ii promoter in response to oxidative stress GO:0043619 0 0.014
protein localization to nucleus GO:0034504 3 0.014
positive regulation of cell cycle GO:0045787 3 0.014
regulation of cell death GO:0010941 103 0.013
gastrulation with mouth forming second GO:0001702 44 0.013
cellular response to extracellular stimulus GO:0031668 2 0.013
defense response to bacterium GO:0042742 22 0.013
liver development GO:0001889 96 0.013
regulation of cellular metabolic process GO:0031323 320 0.013
Mouse
wnt signaling pathway GO:0016055 80 0.013
negative regulation of response to dna damage stimulus GO:2001021 3 0.013
gtp catabolic process GO:0006184 2 0.013
neurotransmitter transport GO:0006836 2 0.013
intracellular signal transduction GO:0035556 85 0.013
regulation of ras gtpase activity GO:0032318 2 0.013
rna metabolic process GO:0016070 219 0.013
Mouse
cell cycle g1 s phase transition GO:0044843 1 0.013
cell cycle arrest GO:0007050 1 0.013
regulation of primary metabolic process GO:0080090 311 0.013
Mouse
establishment of synaptic vesicle localization GO:0097480 1 0.013
regulation of extrinsic apoptotic signaling pathway GO:2001236 3 0.013
cell surface receptor signaling pathway GO:0007166 325 0.012
cellular cation homeostasis GO:0030003 17 0.012
regulation of cellular response to stress GO:0080135 20 0.012
regulation of cytoplasmic transport GO:1903649 4 0.012
cell aging GO:0007569 2 0.012
regulation of cellular ketone metabolic process GO:0010565 7 0.012
establishment of localization GO:0051234 244 0.012
organic cyclic compound metabolic process GO:1901360 301 0.012
Mouse
positive regulation of translation GO:0045727 1 0.012
macromolecule localization GO:0033036 54 0.012
Worm
regulation of sequestering of calcium ion GO:0051282 4 0.012
multicellular organism growth GO:0035264 4 0.012
metal ion homeostasis GO:0055065 26 0.012
mitotic dna damage checkpoint GO:0044773 4 0.012
mesenchyme development GO:0060485 127 0.012
regulation of hormone secretion GO:0046883 2 0.012
spliceosomal complex assembly GO:0000245 1 0.012
sensory perception GO:0007600 39 0.012
macromolecular complex assembly GO:0065003 35 0.012
membrane organization GO:0061024 21 0.012
aromatic compound biosynthetic process GO:0019438 217 0.012
Mouse
extrinsic apoptotic signaling pathway via death domain receptors GO:0008625 1 0.011
locomotory behavior GO:0007626 34 0.011
spindle assembly involved in meiosis GO:0090306 1 0.011
heterocycle metabolic process GO:0046483 290 0.011
Mouse
response to other organism GO:0051707 97 0.011
blood circulation GO:0008015 87 0.011
protein import GO:0017038 3 0.011
protein metabolic process GO:0019538 183 0.011
multi organism cellular process GO:0044764 2 0.011
regulation of macromolecule biosynthetic process GO:0010556 225 0.011
Mouse
regulation of protein import into nucleus GO:0042306 2 0.011
mesenchymal cell development GO:0014031 78 0.011
response to carbohydrate GO:0009743 3 0.011
positive regulation of immune effector process GO:0002699 3 0.011
cellular metal ion homeostasis GO:0006875 16 0.011
golgi vesicle transport GO:0048193 3 0.011
cellular component assembly GO:0022607 170 0.011
negative regulation of nuclear division GO:0051784 3 0.011
cell morphogenesis GO:0000902 289 0.011
female gonad development GO:0008585 4 0.011
inner ear receptor stereocilium organization GO:0060122 8 0.011
negative regulation of cell death GO:0060548 60 0.011
response to nutrient GO:0007584 3 0.011
regulation of metal ion transport GO:0010959 4 0.011
hemopoiesis GO:0030097 183 0.011
central nervous system neuron axonogenesis GO:0021955 18 0.010
central nervous system neuron differentiation GO:0021953 74 0.010
cellular biogenic amine metabolic process GO:0006576 2 0.010
central nervous system development GO:0007417 387 0.010
cellular localization GO:0051641 97 0.010
death GO:0016265 121 0.010
myeloid cell development GO:0061515 32 0.010
cellular lipid metabolic process GO:0044255 36 0.010
cell motility GO:0048870 244 0.010
positive regulation of neuron death GO:1901216 1 0.010
protein complex assembly GO:0006461 30 0.010
single organism nuclear import GO:1902593 3 0.010
neurotransmitter secretion GO:0007269 2 0.010
meiosis i GO:0007127 1 0.010
calcium ion transport into cytosol GO:0060402 3 0.010
nuclear import GO:0051170 3 0.010

eaf2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.028
intestinal cancer DOID:10155 0 0.026
disease of cellular proliferation DOID:14566 0 0.026
cancer DOID:162 0 0.026
colorectal cancer DOID:9256 0 0.026
colon cancer DOID:219 0 0.026
large intestine cancer DOID:5672 0 0.026
organ system cancer DOID:0050686 0 0.026
colon carcinoma DOID:1520 0 0.026
gastrointestinal system cancer DOID:3119 0 0.026
nervous system disease DOID:863 0 0.022
neurodegenerative disease DOID:1289 0 0.020
central nervous system disease DOID:331 0 0.020