Danio rerio

12 known processes

edar

ectodysplasin A receptor

edar biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
appendage development GO:0048736 80 0.209
blood vessel development GO:0001568 246 0.180
monovalent inorganic cation transport GO:0015672 42 0.153
fin development GO:0033333 77 0.151
larval development GO:0002164 2 0.136
medial fin development GO:0033338 16 0.130
medial fin morphogenesis GO:0035141 14 0.129
inorganic ion transmembrane transport GO:0098660 57 0.114
embryonic medial fin morphogenesis GO:0035122 6 0.111
regionalization GO:0003002 274 0.108
ion transport GO:0006811 114 0.104
cognition GO:0050890 1 0.101
determination of dorsal ventral asymmetry GO:0048262 34 0.092
caudal fin morphogenesis GO:0035143 7 0.089
caudal fin development GO:0033336 9 0.088
fin regeneration GO:0031101 51 0.082
organism emergence from protective structure GO:0071684 4 0.078
regulation of transmembrane transport GO:0034762 18 0.074
locomotor rhythm GO:0045475 3 0.073
cellular macromolecule metabolic process GO:0044260 391 0.069
organic cyclic compound metabolic process GO:1901360 301 0.067
behavior GO:0007610 74 0.065
blood vessel morphogenesis GO:0048514 216 0.064
digestive system development GO:0055123 289 0.062
skeletal system development GO:0001501 181 0.062
bone development GO:0060348 14 0.061
regeneration GO:0031099 91 0.061
fin morphogenesis GO:0033334 53 0.060
embryonic caudal fin morphogenesis GO:0035124 3 0.056
response to drug GO:0042493 3 0.055
female sex differentiation GO:0046660 4 0.055
organic cyclic compound biosynthetic process GO:1901362 223 0.055
negative regulation of biological process GO:0048519 304 0.055
cell projection organization GO:0030030 284 0.054
cell morphogenesis involved in differentiation GO:0000904 195 0.053
single organism localization GO:1902578 225 0.052
cellular aromatic compound metabolic process GO:0006725 295 0.052
enzyme linked receptor protein signaling pathway GO:0007167 106 0.050
transmembrane transport GO:0055085 120 0.049
signal transduction GO:0007165 455 0.048
mononuclear cell proliferation GO:0032943 1 0.047
post anal tail morphogenesis GO:0036342 19 0.045
aging GO:0007568 2 0.045
cell substrate adhesion GO:0031589 4 0.045
cell part morphogenesis GO:0032990 246 0.044
embryonic organ development GO:0048568 381 0.044
embryonic skeletal system morphogenesis GO:0048704 93 0.043
cation transport GO:0006812 81 0.042
metal ion transport GO:0030001 58 0.040
vasculature development GO:0001944 278 0.040
female gonad development GO:0008585 4 0.039
cellular component assembly GO:0022607 170 0.039
inorganic cation transmembrane transport GO:0098662 50 0.039
embryo development ending in birth or egg hatching GO:0009792 271 0.039
positive regulation of cell cycle GO:0045787 3 0.037
nitrogen compound metabolic process GO:0006807 319 0.037
phagocytosis engulfment GO:0006911 1 0.037
central nervous system development GO:0007417 387 0.037
homeostatic process GO:0042592 142 0.036
rna metabolic process GO:0016070 219 0.036
internal peptidyl lysine acetylation GO:0018393 2 0.036
growth GO:0040007 174 0.036
determination of ventral identity GO:0048264 21 0.035
internal protein amino acid acetylation GO:0006475 2 0.035
eye development GO:0001654 277 0.035
cation homeostasis GO:0055080 33 0.034
ribonucleoside monophosphate catabolic process GO:0009158 4 0.034
response to external stimulus GO:0009605 264 0.033
rhythmic behavior GO:0007622 5 0.033
organic substance biosynthetic process GO:1901576 289 0.033
positive regulation of cellular process GO:0048522 201 0.032
organelle organization GO:0006996 227 0.032
immune system development GO:0002520 191 0.030
stem cell maintenance GO:0019827 4 0.030
angiogenesis GO:0001525 158 0.030
programmed cell death GO:0012501 119 0.030
tube morphogenesis GO:0035239 349 0.030
macromolecule biosynthetic process GO:0009059 227 0.029
potassium ion transport GO:0006813 10 0.029
maintenance of location GO:0051235 4 0.029
gene expression GO:0010467 252 0.029
tissue regeneration GO:0042246 74 0.029
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 50 0.028
regulation of gene expression GO:0010468 265 0.028
regulation of metabolic process GO:0019222 359 0.028
regulation of primary metabolic process GO:0080090 311 0.028
positive regulation of catabolic process GO:0009896 4 0.028
locomotion GO:0040011 313 0.028
transcription dna templated GO:0006351 181 0.028
cell morphogenesis GO:0000902 289 0.027
lymphocyte proliferation GO:0046651 1 0.027
response to chemical GO:0042221 320 0.027
regulation of cell activation GO:0050865 1 0.027
heterocycle metabolic process GO:0046483 290 0.026
small molecule metabolic process GO:0044281 77 0.026
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.026
regulation of signal transduction GO:0009966 225 0.026
positive regulation of protein complex assembly GO:0031334 2 0.026
heterocycle biosynthetic process GO:0018130 215 0.026
nucleoside monophosphate catabolic process GO:0009125 4 0.026
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 1 0.026
establishment of localization GO:0051234 244 0.026
lens fiber cell morphogenesis GO:0070309 3 0.025
regulation of multicellular organismal process GO:0051239 277 0.025
specification of symmetry GO:0009799 204 0.025
neuron projection morphogenesis GO:0048812 161 0.025
multicellular organism growth GO:0035264 4 0.025
protein acetylation GO:0006473 2 0.025
single organism behavior GO:0044708 24 0.025
cell migration GO:0016477 237 0.024
development of primary female sexual characteristics GO:0046545 4 0.024
hatching GO:0035188 4 0.024
response to amino acid GO:0043200 2 0.024
response to superoxide GO:0000303 2 0.024
embryonic limb morphogenesis GO:0030326 2 0.023
cellular component morphogenesis GO:0032989 336 0.023
developmental growth involved in morphogenesis GO:0060560 86 0.023
regulation of multicellular organism growth GO:0040014 4 0.023
positive regulation of protein polymerization GO:0032273 2 0.023
protein polymerization GO:0051258 4 0.023
positive regulation of biological process GO:0048518 253 0.022
cellular component movement GO:0006928 335 0.022
positive regulation of cellular component biogenesis GO:0044089 3 0.022
germ line stem cell maintenance GO:0030718 2 0.022
response to stress GO:0006950 263 0.022
skeletal system morphogenesis GO:0048705 102 0.022
protein localization to plasma membrane GO:0072659 1 0.021
cellular nitrogen compound biosynthetic process GO:0044271 218 0.021
peptidyl lysine acetylation GO:0018394 2 0.021
regulation of signaling GO:0023051 235 0.021
developmental growth GO:0048589 166 0.021
water transport GO:0006833 15 0.021
regulation of transcription dna templated GO:0006355 213 0.021
circadian behavior GO:0048512 5 0.021
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.021
regulation of tube size GO:0035150 2 0.021
establishment of protein localization to plasma membrane GO:0090002 1 0.021
bmp signaling pathway GO:0030509 52 0.021
regulation of biosynthetic process GO:0009889 250 0.020
regulation of nitrogen compound metabolic process GO:0051171 251 0.020
immune system process GO:0002376 241 0.020
cellular protein catabolic process GO:0044257 4 0.020
superoxide metabolic process GO:0006801 2 0.020
ubiquitin dependent protein catabolic process GO:0006511 3 0.020
single organism transport GO:0044765 206 0.020
regulation of cell communication GO:0010646 232 0.020
regulation of cell cycle GO:0051726 52 0.020
cellular nitrogen compound metabolic process GO:0034641 290 0.020
negative regulation of metabolic process GO:0009892 86 0.019
dorsal ventral pattern formation GO:0009953 125 0.019
hematopoietic or lymphoid organ development GO:0048534 191 0.019
mesoderm morphogenesis GO:0048332 51 0.019
trabecula morphogenesis GO:0061383 2 0.019
cell motility GO:0048870 244 0.019
gastrulation GO:0007369 208 0.019
regulation of cellular amino acid metabolic process GO:0006521 0 0.019
anterior posterior pattern specification GO:0009952 152 0.019
cell matrix adhesion GO:0007160 4 0.019
generation of neurons GO:0048699 385 0.018
apoptotic process involved in development GO:1902742 2 0.018
purine ribonucleoside monophosphate catabolic process GO:0009169 4 0.018
regulation of wound healing GO:0061041 2 0.018
mesoderm development GO:0007498 88 0.018
single organism metabolic process GO:0044710 217 0.018
lamellipodium organization GO:0097581 1 0.018
regulation of cytokine production GO:0001817 3 0.018
single organism biosynthetic process GO:0044711 71 0.018
appendage morphogenesis GO:0035107 56 0.018
b cell activation GO:0042113 2 0.018
skin development GO:0043588 54 0.018
taxis GO:0042330 109 0.018
negative regulation of cellular process GO:0048523 283 0.018
carboxylic acid metabolic process GO:0019752 22 0.018
leukocyte proliferation GO:0070661 1 0.018
regulation of cellular component size GO:0032535 30 0.018
regulation of establishment of protein localization GO:0070201 4 0.018
negative regulation of small gtpase mediated signal transduction GO:0051058 1 0.018
germ cell development GO:0007281 22 0.017
brain development GO:0007420 293 0.017
regulation of peptidase activity GO:0052547 23 0.017
ion transmembrane transport GO:0034220 91 0.017
spermatid development GO:0007286 2 0.017
meiotic cell cycle process GO:1903046 3 0.017
positive regulation of cytoskeleton organization GO:0051495 3 0.017
sensory perception of chemical stimulus GO:0007606 3 0.017
regulation of oocyte development GO:0060281 3 0.017
regulation of establishment of protein localization to plasma membrane GO:0090003 1 0.017
regulation of cell death GO:0010941 103 0.017
regulation of rna metabolic process GO:0051252 224 0.017
regulation of protein polymerization GO:0032271 2 0.017
ameboidal type cell migration GO:0001667 143 0.017
guanosine containing compound metabolic process GO:1901068 4 0.017
negative regulation of nucleocytoplasmic transport GO:0046823 2 0.017
mitochondrion organization GO:0007005 4 0.017
positive regulation of cellular catabolic process GO:0031331 3 0.017
determination of bilateral symmetry GO:0009855 204 0.017
regulation of biological quality GO:0065008 263 0.017
protein metabolic process GO:0019538 183 0.016
rhythmic process GO:0048511 21 0.016
sensory organ development GO:0007423 393 0.016
cell surface receptor signaling pathway GO:0007166 325 0.016
regulation of macromolecule metabolic process GO:0060255 317 0.016
cellular amine metabolic process GO:0044106 2 0.016
calcium ion import GO:0070509 4 0.016
single organism cell adhesion GO:0098602 29 0.016
actin cytoskeleton organization GO:0030036 63 0.016
lamellipodium assembly GO:0030032 1 0.016
protein acylation GO:0043543 3 0.016
extracellular matrix assembly GO:0085029 1 0.016
notochord morphogenesis GO:0048570 17 0.016
neuron projection development GO:0031175 180 0.016
localization of cell GO:0051674 244 0.016
positive regulation of map kinase activity GO:0043406 3 0.016
nephron epithelium morphogenesis GO:0072088 1 0.016
neuron development GO:0048666 262 0.016
regulation of protein complex assembly GO:0043254 3 0.016
transport GO:0006810 220 0.016
developmental programmed cell death GO:0010623 4 0.015
negative regulation of cysteine type endopeptidase activity GO:2000117 8 0.015
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.015
ovulation cycle GO:0042698 2 0.015
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 4 0.015
cell projection morphogenesis GO:0048858 244 0.015
positive regulation of myeloid cell differentiation GO:0045639 2 0.015
actin filament polymerization GO:0030041 2 0.015
response to wounding GO:0009611 116 0.015
phosphatidylinositol mediated signaling GO:0048015 2 0.015
regulation of cellular biosynthetic process GO:0031326 245 0.015
regulation of cysteine type endopeptidase activity GO:2000116 21 0.015
cell aging GO:0007569 2 0.015
atp catabolic process GO:0006200 4 0.015
negative regulation of cytoplasmic transport GO:1903650 2 0.015
cellular ketone metabolic process GO:0042180 11 0.015
metal ion homeostasis GO:0055065 26 0.015
oxoacid metabolic process GO:0043436 31 0.015
cellular response to nutrient levels GO:0031669 2 0.015
response to hydrogen peroxide GO:0042542 3 0.015
positive regulation of synaptic growth at neuromuscular junction GO:0045887 1 0.015
regulation of epidermis development GO:0045682 2 0.015
stem cell division GO:0017145 1 0.015
sensory perception GO:0007600 39 0.015
meiotic chromosome segregation GO:0045132 3 0.015
rna modification GO:0009451 2 0.015
cellular protein metabolic process GO:0044267 129 0.015
reactive oxygen species metabolic process GO:0072593 6 0.015
regulation of nucleoside metabolic process GO:0009118 2 0.015
regulation of rho protein signal transduction GO:0035023 2 0.015
cellular response to extracellular stimulus GO:0031668 2 0.015
epithelial cell differentiation GO:0030855 116 0.015
regulation of meiotic cell cycle GO:0051445 1 0.014
multi organism cellular process GO:0044764 2 0.014
modification dependent macromolecule catabolic process GO:0043632 3 0.014
gtp metabolic process GO:0046039 4 0.014
regulation of cellular protein catabolic process GO:1903362 1 0.014
single organism organelle organization GO:1902589 199 0.014
purine nucleoside monophosphate catabolic process GO:0009128 4 0.014
positive regulation of transport GO:0051050 2 0.014
regulation of bmp signaling pathway GO:0030510 39 0.014
regulation of locomotion GO:0040012 55 0.014
neurological system process GO:0050877 62 0.014
positive regulation of synapse assembly GO:0051965 1 0.014
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 20 0.014
nucleic acid metabolic process GO:0090304 244 0.014
wound healing GO:0042060 90 0.014
negative regulation of macromolecule metabolic process GO:0010605 76 0.014
regulation of proteolysis GO:0030162 24 0.014
regulation of bone mineralization GO:0030500 2 0.014
spermatid differentiation GO:0048515 2 0.014
regulation of cellular amine metabolic process GO:0033238 0 0.014
synaptic growth at neuromuscular junction GO:0051124 2 0.014
regulation of protein transport GO:0051223 3 0.014
regulation of protein metabolic process GO:0051246 56 0.014
cellular biosynthetic process GO:0044249 286 0.014
epithelial cell development GO:0002064 42 0.014
oocyte maturation GO:0001556 4 0.013
endosomal transport GO:0016197 2 0.013
heart morphogenesis GO:0003007 156 0.013
chemical homeostasis GO:0048878 49 0.013
formation of primary germ layer GO:0001704 62 0.013
regulation of autophagy GO:0010506 3 0.013
secondary metabolic process GO:0019748 3 0.013
endochondral bone growth GO:0003416 2 0.013
organic acid metabolic process GO:0006082 31 0.013
meiotic nuclear division GO:0007126 4 0.013
response to uv GO:0009411 3 0.013
multicellular organismal metabolic process GO:0044236 2 0.013
regulation of neurotransmitter transport GO:0051588 1 0.013
segmentation GO:0035282 97 0.013
regulation of neurotransmitter secretion GO:0046928 1 0.013
positive regulation of nucleotide catabolic process GO:0030813 1 0.013
protein maturation GO:0051604 12 0.013
protein polyubiquitination GO:0000209 4 0.013
oogenesis GO:0048477 14 0.013
organonitrogen compound metabolic process GO:1901564 74 0.013
death GO:0016265 121 0.013
protein localization to nucleus GO:0034504 3 0.013
melanin metabolic process GO:0006582 2 0.012
apoptotic process GO:0006915 116 0.012
muscle cell differentiation GO:0042692 139 0.012
monoamine transport GO:0015844 1 0.012
protein processing GO:0016485 12 0.012
determination of heart left right asymmetry GO:0061371 117 0.012
regulation of immune system process GO:0002682 34 0.012
response to inorganic substance GO:0010035 38 0.012
cellular localization GO:0051641 97 0.012
biosynthetic process GO:0009058 294 0.012
negative regulation of intracellular transport GO:0032387 3 0.012
positive regulation of epithelial cell migration GO:0010634 2 0.012
cellular component biogenesis GO:0044085 178 0.012
trabecula formation GO:0060343 2 0.012
membrane invagination GO:0010324 1 0.012
system process GO:0003008 185 0.012
water homeostasis GO:0030104 4 0.012
alcohol biosynthetic process GO:0046165 2 0.012
sensory perception of smell GO:0007608 2 0.012
regulation of endopeptidase activity GO:0052548 23 0.012
regulation of protein modification by small protein conjugation or removal GO:1903320 3 0.012
transcription from rna polymerase ii promoter GO:0006366 80 0.012
digestive tract development GO:0048565 265 0.012
organophosphate metabolic process GO:0019637 37 0.012
potassium ion transmembrane transport GO:0071805 10 0.012
regulation of transporter activity GO:0032409 2 0.012
positive regulation of immune effector process GO:0002699 3 0.012
golgi vesicle transport GO:0048193 3 0.011
eye morphogenesis GO:0048592 144 0.011
regulation of nucleocytoplasmic transport GO:0046822 2 0.011
response to topologically incorrect protein GO:0035966 2 0.011
modification dependent protein catabolic process GO:0019941 3 0.011
regulation of leukocyte mediated cytotoxicity GO:0001910 1 0.011
nephron tubule morphogenesis GO:0072078 1 0.011
positive regulation of nucleoside metabolic process GO:0045979 1 0.011
negative regulation of chromosome organization GO:2001251 1 0.011
positive regulation of multi organism process GO:0043902 3 0.011
cell death GO:0008219 121 0.011
cellular transition metal ion homeostasis GO:0046916 3 0.011
negative regulation of protein transport GO:0051224 3 0.011
immune effector process GO:0002252 23 0.011
aromatic compound biosynthetic process GO:0019438 217 0.011
post embryonic organ development GO:0048569 4 0.011
positive regulation of dna metabolic process GO:0051054 1 0.011
response to corticosteroid GO:0031960 1 0.011
catechol containing compound metabolic process GO:0009712 2 0.011
regulation of organ growth GO:0046620 3 0.011
regulation of blood coagulation GO:0030193 1 0.011
embryonic hemopoiesis GO:0035162 53 0.011
immune response GO:0006955 28 0.011
ion homeostasis GO:0050801 41 0.011
regulation of apoptotic process GO:0042981 98 0.011
regulation of synapse assembly GO:0051963 3 0.011
positive regulation of response to stimulus GO:0048584 80 0.011
lens fiber cell development GO:0070307 3 0.011
cellular response to external stimulus GO:0071496 2 0.011
regulation of cell growth GO:0001558 29 0.011
regulation of transmembrane transporter activity GO:0022898 2 0.011
positive regulation of bmp signaling pathway GO:0030513 10 0.011
regulation of metal ion transport GO:0010959 4 0.011
regulation of protein localization to plasma membrane GO:1903076 1 0.011
response to transition metal nanoparticle GO:1990267 28 0.011
negative regulation of signaling GO:0023057 96 0.011
determination of left right symmetry GO:0007368 179 0.011
heterocycle catabolic process GO:0046700 15 0.011
negative regulation of intracellular protein transport GO:0090317 3 0.011
female meiosis chromosome segregation GO:0016321 1 0.011
gamete generation GO:0007276 33 0.010
head development GO:0060322 303 0.010
regulation of lipid transport GO:0032368 4 0.010
rna localization GO:0006403 4 0.010
regulation of stem cell differentiation GO:2000736 4 0.010
negative regulation of cellular catabolic process GO:0031330 3 0.010
morphogenesis of an epithelium GO:0002009 333 0.010
actin polymerization or depolymerization GO:0008154 2 0.010
viral process GO:0016032 1 0.010
amine metabolic process GO:0009308 2 0.010
somatic muscle development GO:0007525 4 0.010

edar disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.084
disease of cellular proliferation DOID:14566 0 0.022
cancer DOID:162 0 0.022
musculoskeletal system disease DOID:17 0 0.020
connective tissue disease DOID:65 0 0.020
bone disease DOID:0080001 0 0.017
immune system disease DOID:2914 0 0.015
bone development disease DOID:0080006 0 0.014
nervous system disease DOID:863 0 0.014
sensory system disease DOID:0050155 0 0.012
eye and adnexa disease DOID:1492 0 0.012
eye disease DOID:5614 0 0.012
retinal disease DOID:5679 0 0.012
organ system cancer DOID:0050686 0 0.012