Danio rerio

16 known processes

ednrb1

endothelin receptor B

(Aliases: ednrb1a)

ednrb1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
positive regulation of tyrosine phosphorylation of stat3 protein GO:0042517 1 0.634
xanthophore differentiation GO:0050936 3 0.628
positive regulation of neural retina development GO:0061075 1 0.437
transmembrane transport GO:0055085 120 0.408
melanin biosynthetic process GO:0042438 1 0.404
catecholamine biosynthetic process GO:0042423 2 0.369
alpha amino acid metabolic process GO:1901605 3 0.356
negative regulation of biological process GO:0048519 304 0.346
cellular macromolecule metabolic process GO:0044260 391 0.334
pigmentation GO:0043473 85 0.330
developmental pigmentation GO:0048066 48 0.289
phenol containing compound biosynthetic process GO:0046189 4 0.271
caudal fin development GO:0033336 9 0.269
organic substance biosynthetic process GO:1901576 289 0.260
regulation of neural retina development GO:0061074 2 0.257
regulation of neurological system process GO:0031644 2 0.243
phenol containing compound metabolic process GO:0018958 5 0.226
regulation of tyrosine phosphorylation of stat3 protein GO:0042516 1 0.219
dopamine biosynthetic process GO:0042416 2 0.211
regulation of system process GO:0044057 40 0.209
organonitrogen compound biosynthetic process GO:1901566 47 0.203
positive regulation of biological process GO:0048518 253 0.201
programmed cell death GO:0012501 119 0.195
response to external stimulus GO:0009605 264 0.193
regulation of primary metabolic process GO:0080090 311 0.192
regulation of cell death GO:0010941 103 0.188
neuromuscular synaptic transmission GO:0007274 2 0.186
macromolecule biosynthetic process GO:0009059 227 0.176
generation of neurons GO:0048699 385 0.172
cellular biosynthetic process GO:0044249 286 0.172
pigment cell differentiation GO:0050931 38 0.163
single organism transport GO:0044765 206 0.158
actin filament based process GO:0030029 64 0.139
organonitrogen compound metabolic process GO:1901564 74 0.138
nitrogen compound metabolic process GO:0006807 319 0.136
biosynthetic process GO:0009058 294 0.135
cell projection organization GO:0030030 284 0.132
positive regulation of retina development in camera type eye GO:1902868 1 0.126
neurological system process GO:0050877 62 0.124
microglia differentiation GO:0014004 1 0.118
small molecule metabolic process GO:0044281 77 0.112
aromatic amino acid family metabolic process GO:0009072 1 0.111
ion transport GO:0006811 114 0.110
cellular amine metabolic process GO:0044106 2 0.109
melanin metabolic process GO:0006582 2 0.107
larval development GO:0002164 2 0.105
organic cyclic compound metabolic process GO:1901360 301 0.104
regulation of apoptotic process GO:0042981 98 0.103
negative regulation of cellular process GO:0048523 283 0.103
positive regulation of cell killing GO:0031343 2 0.099
positive regulation of cellular process GO:0048522 201 0.099
regulation of signal transduction GO:0009966 225 0.099
organic cyclic compound biosynthetic process GO:1901362 223 0.099
extrinsic apoptotic signaling pathway GO:0097191 3 0.098
regulation of nitrogen compound metabolic process GO:0051171 251 0.098
regulation of cellular biosynthetic process GO:0031326 245 0.098
mononuclear cell migration GO:0071674 1 0.098
homeostasis of number of cells GO:0048872 62 0.095
signal transduction GO:0007165 455 0.091
blood vessel development GO:0001568 246 0.090
heart contraction GO:0060047 71 0.089
sensory organ development GO:0007423 393 0.087
secondary metabolic process GO:0019748 3 0.087
cellular macromolecule biosynthetic process GO:0034645 224 0.087
single organism localization GO:1902578 225 0.083
actin cytoskeleton organization GO:0030036 63 0.079
ion transmembrane transport GO:0034220 91 0.078
osteoclast differentiation GO:0030316 1 0.077
catechol containing compound biosynthetic process GO:0009713 2 0.076
dopamine metabolic process GO:0042417 2 0.073
macromolecule modification GO:0043412 111 0.072
cellular amino acid metabolic process GO:0006520 7 0.071
medial fin development GO:0033338 16 0.069
negative regulation of signaling GO:0023057 96 0.069
smooth muscle contraction GO:0006939 2 0.069
cellular aromatic compound metabolic process GO:0006725 295 0.069
neuron development GO:0048666 262 0.069
regulation of retina development in camera type eye GO:1902866 2 0.068
regulation of establishment of protein localization GO:0070201 4 0.068
post embryonic organ morphogenesis GO:0048563 1 0.067
organelle organization GO:0006996 227 0.065
regulation of cellular metabolic process GO:0031323 320 0.065
regulation of macromolecule metabolic process GO:0060255 317 0.064
positive regulation of transport GO:0051050 2 0.064
cell death GO:0008219 121 0.060
taxis GO:0042330 109 0.060
regulation of multicellular organismal process GO:0051239 277 0.060
single organism organelle organization GO:1902589 199 0.060
single organism biosynthetic process GO:0044711 71 0.059
detection of mechanical stimulus involved in sensory perception of sound GO:0050910 3 0.059
immune system development GO:0002520 191 0.059
negative regulation of cell death GO:0060548 60 0.059
amine metabolic process GO:0009308 2 0.058
regulation of biological quality GO:0065008 263 0.057
digestive tract development GO:0048565 265 0.057
blood vessel morphogenesis GO:0048514 216 0.056
death GO:0016265 121 0.056
venous endothelial cell migration involved in lymph vessel development GO:0060855 4 0.056
er nucleus signaling pathway GO:0006984 2 0.055
positive regulation of macrophage chemotaxis GO:0010759 1 0.054
cell migration GO:0016477 237 0.054
cell morphogenesis GO:0000902 289 0.054
positive regulation of multicellular organismal process GO:0051240 52 0.053
digestive system development GO:0055123 289 0.053
regulation of response to stimulus GO:0048583 269 0.052
positive regulation of myeloid cell differentiation GO:0045639 2 0.050
regulation of cellular amine metabolic process GO:0033238 0 0.050
negative regulation of programmed cell death GO:0043069 58 0.050
negative regulation of macromolecule metabolic process GO:0010605 76 0.049
neuron projection development GO:0031175 180 0.049
rna metabolic process GO:0016070 219 0.048
system process GO:0003008 185 0.048
behavior GO:0007610 74 0.047
embryonic organ development GO:0048568 381 0.046
neuroepithelial cell differentiation GO:0060563 26 0.046
positive regulation of metabolic process GO:0009893 108 0.046
tissue remodeling GO:0048771 4 0.045
melanocyte differentiation GO:0030318 26 0.045
apoptotic process GO:0006915 116 0.045
regulation of macromolecule biosynthetic process GO:0010556 225 0.045
catechol containing compound metabolic process GO:0009712 2 0.044
transport GO:0006810 220 0.044
gland development GO:0048732 143 0.044
cellular protein modification process GO:0006464 100 0.043
regulation of catalytic activity GO:0050790 55 0.043
response to stress GO:0006950 263 0.043
cognition GO:0050890 1 0.042
positive regulation of catabolic process GO:0009896 4 0.041
cellular nitrogen compound metabolic process GO:0034641 290 0.041
catecholamine metabolic process GO:0006584 2 0.040
oxoacid metabolic process GO:0043436 31 0.040
regulation of rna metabolic process GO:0051252 224 0.040
heterocycle biosynthetic process GO:0018130 215 0.039
axon development GO:0061564 166 0.037
neuron differentiation GO:0030182 353 0.037
cell motility GO:0048870 244 0.037
regulation of nucleic acid templated transcription GO:1903506 213 0.036
macromolecular complex subunit organization GO:0043933 74 0.036
regulation of programmed cell death GO:0043067 101 0.035
aging GO:0007568 2 0.035
negative regulation of gene expression GO:0010629 65 0.035
retina development in camera type eye GO:0060041 146 0.035
regulation of jak stat cascade GO:0046425 3 0.035
positive regulation of signal transduction GO:0009967 56 0.034
aromatic compound biosynthetic process GO:0019438 217 0.034
regulation of cell communication GO:0010646 232 0.034
carboxylic acid metabolic process GO:0019752 22 0.034
organism emergence from protective structure GO:0071684 4 0.034
cellular component morphogenesis GO:0032989 336 0.033
regulation of developmental process GO:0050793 247 0.032
protein polymerization GO:0051258 4 0.032
regulation of heart contraction GO:0008016 32 0.032
b cell activation GO:0042113 2 0.031
localization of cell GO:0051674 244 0.031
response to other organism GO:0051707 97 0.031
organic acid metabolic process GO:0006082 31 0.031
response to chemical GO:0042221 320 0.031
negative regulation of feeding behavior GO:2000252 2 0.031
nucleic acid metabolic process GO:0090304 244 0.031
negative regulation of apoptotic process GO:0043066 55 0.030
cellular component movement GO:0006928 335 0.029
ameboidal type cell migration GO:0001667 143 0.029
endothelial cell development GO:0001885 12 0.029
single organism reproductive process GO:0044702 40 0.029
regulation of macrophage chemotaxis GO:0010758 1 0.028
determination of bilateral symmetry GO:0009855 204 0.028
regulation of gene expression GO:0010468 265 0.028
inorganic ion transmembrane transport GO:0098660 57 0.028
neurotransmitter transport GO:0006836 2 0.028
eye development GO:0001654 277 0.028
cellular component biogenesis GO:0044085 178 0.027
regulation of mononuclear cell migration GO:0071675 1 0.027
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 68 0.026
heterocycle metabolic process GO:0046483 290 0.026
ventral spinal cord development GO:0021517 35 0.026
cell surface receptor signaling pathway GO:0007166 325 0.026
cellular pigmentation GO:0033059 30 0.026
regulation of metabolic process GO:0019222 359 0.026
positive regulation of developmental process GO:0051094 50 0.025
epithelial cell cell adhesion GO:0090136 1 0.025
establishment of localization GO:0051234 244 0.025
removal of superoxide radicals GO:0019430 2 0.025
phosphate containing compound metabolic process GO:0006796 108 0.025
nucleobase containing compound metabolic process GO:0006139 274 0.025
positive regulation of apoptotic signaling pathway GO:2001235 1 0.025
endothelial cell differentiation GO:0045446 20 0.025
transcription dna templated GO:0006351 181 0.025
positive regulation of cellular metabolic process GO:0031325 94 0.025
embryonic hemopoiesis GO:0035162 53 0.025
cellular nitrogen compound biosynthetic process GO:0044271 218 0.025
chloride transmembrane transport GO:1902476 4 0.024
epithelial cell differentiation GO:0030855 116 0.024
membrane repolarization GO:0086009 2 0.024
regulation of cell shape GO:0008360 1 0.023
gliogenesis GO:0042063 45 0.023
regulation of signaling GO:0023051 235 0.023
maintenance of location GO:0051235 4 0.023
stem cell maintenance GO:0019827 4 0.022
response to biotic stimulus GO:0009607 97 0.022
cellular response to lipid GO:0071396 39 0.022
central nervous system neuron differentiation GO:0021953 74 0.022
septum transversum development GO:0003343 4 0.022
chondrocyte intercalation involved in growth plate cartilage morphogenesis GO:0003428 1 0.022
single organism metabolic process GO:0044710 217 0.022
regulation of membrane potential GO:0042391 23 0.022
vasculature development GO:0001944 278 0.022
positive regulation of nucleobase containing compound metabolic process GO:0045935 69 0.022
multi organism process GO:0051704 134 0.021
osteoclast development GO:0036035 1 0.021
carbohydrate derivative biosynthetic process GO:1901137 43 0.021
positive regulation of extrinsic apoptotic signaling pathway GO:2001238 1 0.021
caudal fin morphogenesis GO:0035143 7 0.021
regulation of multicellular organismal development GO:2000026 223 0.020
negative regulation of multicellular organismal process GO:0051241 69 0.020
gene expression GO:0010467 252 0.020
growth GO:0040007 174 0.020
specification of symmetry GO:0009799 204 0.020
positive regulation of leukocyte differentiation GO:1902107 1 0.020
cellular protein metabolic process GO:0044267 129 0.020
muscle contraction GO:0006936 18 0.020
positive regulation of jak stat cascade GO:0046427 2 0.020
melanocyte migration GO:0097324 4 0.020
stem cell differentiation GO:0048863 117 0.019
regulation of cellular amino acid metabolic process GO:0006521 0 0.019
regulation of cytokine production GO:0001817 3 0.019
regulation of protein transport GO:0051223 3 0.019
response to abiotic stimulus GO:0009628 122 0.019
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.019
response to bacterium GO:0009617 58 0.019
chemosensory behavior GO:0007635 1 0.019
cellular response to unfolded protein GO:0034620 2 0.018
regulation of localization GO:0032879 104 0.018
regulation of biosynthetic process GO:0009889 250 0.018
positive regulation of signaling GO:0023056 56 0.018
central nervous system development GO:0007417 387 0.018
locomotor rhythm GO:0045475 3 0.018
phosphorus metabolic process GO:0006793 109 0.018
ovulation cycle GO:0042698 2 0.018
regulation of cell activation GO:0050865 1 0.018
cell differentiation in spinal cord GO:0021515 40 0.017
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.017
developmental growth GO:0048589 166 0.017
endochondral bone growth GO:0003416 2 0.017
internal protein amino acid acetylation GO:0006475 2 0.017
rna biosynthetic process GO:0032774 181 0.017
homeostatic process GO:0042592 142 0.017
b cell differentiation GO:0030183 1 0.017
signal transduction in absence of ligand GO:0038034 1 0.017
cellular ketone metabolic process GO:0042180 11 0.017
stem cell division GO:0017145 1 0.017
camera type eye development GO:0043010 222 0.017
enzyme linked receptor protein signaling pathway GO:0007167 106 0.017
cellular response to chemical stimulus GO:0070887 157 0.017
segment polarity determination GO:0007367 1 0.017
embryonic organ morphogenesis GO:0048562 274 0.017
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.016
negative regulation of cell communication GO:0010648 96 0.016
skeletal system morphogenesis GO:0048705 102 0.016
protein modification process GO:0036211 100 0.016
hematopoietic or lymphoid organ development GO:0048534 191 0.016
tube morphogenesis GO:0035239 349 0.016
monovalent inorganic cation transport GO:0015672 42 0.016
intracellular signal transduction GO:0035556 85 0.016
cation transmembrane transport GO:0098655 65 0.016
protein complex subunit organization GO:0071822 46 0.016
tissue regeneration GO:0042246 74 0.016
embryonic skeletal system morphogenesis GO:0048704 93 0.016
eye pigmentation GO:0048069 4 0.016
ovulation cycle process GO:0022602 2 0.016
muscle structure development GO:0061061 196 0.016
circulatory system process GO:0003013 87 0.016
organophosphate metabolic process GO:0019637 37 0.016
golgi organization GO:0007030 1 0.015
regulation of extrinsic apoptotic signaling pathway GO:2001236 3 0.015
regulation of myeloid leukocyte differentiation GO:0002761 5 0.015
regulation of embryonic development GO:0045995 47 0.014
cell part morphogenesis GO:0032990 246 0.014
positive regulation of cellular amine metabolic process GO:0033240 0 0.014
positive regulation of neural precursor cell proliferation GO:2000179 1 0.014
regulation of multicellular organism growth GO:0040014 4 0.014
leukocyte proliferation GO:0070661 1 0.014
regulation of erk1 and erk2 cascade GO:0070372 4 0.014
lymphocyte proliferation GO:0046651 1 0.014
nucleobase containing compound biosynthetic process GO:0034654 205 0.014
neuron death GO:0070997 21 0.014
mononuclear cell proliferation GO:0032943 1 0.014
antimicrobial humoral response GO:0019730 2 0.014
transcription from rna polymerase ii promoter GO:0006366 80 0.014
jak stat cascade GO:0007259 5 0.014
positive regulation of cell communication GO:0010647 56 0.014
regulation of rna biosynthetic process GO:2001141 213 0.013
heart development GO:0007507 313 0.013
indole containing compound metabolic process GO:0042430 2 0.013
positive regulation of protein metabolic process GO:0051247 23 0.013
neuroblast proliferation GO:0007405 2 0.013
regulation of transport GO:0051049 45 0.013
regulation of anatomical structure morphogenesis GO:0022603 130 0.013
chromatin organization GO:0006325 22 0.013
inorganic cation transmembrane transport GO:0098662 50 0.013
cell projection morphogenesis GO:0048858 244 0.013
oxidation reduction process GO:0055114 41 0.013
angiogenesis GO:0001525 158 0.013
skeletal system development GO:0001501 181 0.013
regulation of tyrosine phosphorylation of stat protein GO:0042509 1 0.013
organic substance transport GO:0071702 58 0.013
chordate embryonic development GO:0043009 271 0.013
synaptic growth at neuromuscular junction GO:0051124 2 0.013
multicellular organism growth GO:0035264 4 0.013
secondary metabolite biosynthetic process GO:0044550 1 0.013
muscle system process GO:0003012 20 0.013
action potential GO:0001508 19 0.013
muscle organ development GO:0007517 101 0.013
fin development GO:0033333 77 0.012
myeloid cell development GO:0061515 32 0.012
reproduction GO:0000003 40 0.012
regulation of cellular protein metabolic process GO:0032268 52 0.012
locomotory behavior GO:0007626 34 0.012
multicellular organism reproduction GO:0032504 35 0.012
lamellipodium assembly GO:0030032 1 0.012
regulation of ion transmembrane transporter activity GO:0032412 2 0.012
negative regulation of signal transduction GO:0009968 94 0.012
determination of intestine left right asymmetry GO:0071908 2 0.012
embryonic limb morphogenesis GO:0030326 2 0.012
internal peptidyl lysine acetylation GO:0018393 2 0.012
cellular response to dna damage stimulus GO:0006974 24 0.012
cardiac atrium morphogenesis GO:0003209 2 0.012
positive regulation of neurogenesis GO:0050769 24 0.012
regulation of intracellular signal transduction GO:1902531 57 0.012
positive regulation of erk1 and erk2 cascade GO:0070374 2 0.011
pharyngeal muscle development GO:0043282 4 0.011
positive regulation of secretion GO:0051047 1 0.011
cytoskeleton organization GO:0007010 96 0.011
macromolecule methylation GO:0043414 19 0.011
spinal cord motor neuron differentiation GO:0021522 26 0.011
metal ion transport GO:0030001 58 0.011
bone remodeling GO:0046849 2 0.011
cation transport GO:0006812 81 0.011
cellular response to hormone stimulus GO:0032870 39 0.011
single organism behavior GO:0044708 24 0.011
positive regulation of gene expression GO:0010628 71 0.011
glial cell differentiation GO:0010001 42 0.011
negative regulation of blood circulation GO:1903523 2 0.011
proepicardium development GO:0003342 4 0.011
mitochondrion organization GO:0007005 4 0.011
regulation of autophagy GO:0010506 3 0.011
response to external biotic stimulus GO:0043207 97 0.011
lamellipodium organization GO:0097581 1 0.011
positive regulation of cellular component biogenesis GO:0044089 3 0.011
cellular biogenic amine metabolic process GO:0006576 2 0.011
nucleic acid templated transcription GO:0097659 181 0.011
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.011
spinal cord development GO:0021510 46 0.011
cellular catabolic process GO:0044248 27 0.011
protein acetylation GO:0006473 2 0.011
defense response GO:0006952 47 0.011
macrophage chemotaxis GO:0048246 3 0.011
protein metabolic process GO:0019538 183 0.011
positive regulation of rna metabolic process GO:0051254 59 0.010
posterior lateral line neuromast development GO:0048919 20 0.010
response to topologically incorrect protein GO:0035966 2 0.010
locomotion GO:0040011 313 0.010
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 50 0.010
neuron projection morphogenesis GO:0048812 161 0.010
cellular response to oxygen containing compound GO:1901701 20 0.010
positive regulation of map kinase activity GO:0043406 3 0.010
positive regulation of macromolecule metabolic process GO:0010604 93 0.010
multicellular organismal reproductive process GO:0048609 35 0.010
t cell differentiation GO:0030217 6 0.010
response to nitrogen compound GO:1901698 19 0.010

ednrb1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
bone development disease DOID:0080006 0 0.041
bone disease DOID:0080001 0 0.041
disease of anatomical entity DOID:7 0 0.041
musculoskeletal system disease DOID:17 0 0.041
connective tissue disease DOID:65 0 0.041
immune system disease DOID:2914 0 0.037
nervous system disease DOID:863 0 0.035
osteochondrodysplasia DOID:2256 0 0.012