Danio rerio

16 known processes

eef2b

eukaryotic translation elongation factor 2b

(Aliases: wu:fe49h02,fe49h02,eef2l,zgc:63584,MGC63584,EEF2)

eef2b biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
larval development GO:0002164 2 0.681
Worm
regulation of translational initiation GO:0006446 1 0.560
single fertilization GO:0007338 3 0.491
aging GO:0007568 2 0.489
Worm
cell cell recognition GO:0009988 1 0.349
translational initiation GO:0006413 3 0.335
positive regulation of translation GO:0045727 1 0.301
Human Yeast
cellular macromolecule metabolic process GO:0044260 391 0.195
Human Yeast Mouse
translation GO:0006412 5 0.193
Human Yeast Mouse
fertilization GO:0009566 3 0.191
mrna polyadenylation GO:0006378 2 0.185
microtubule organizing center organization GO:0031023 1 0.181
spindle assembly involved in mitosis GO:0090307 1 0.150
transport GO:0006810 220 0.120
cell cycle GO:0007049 93 0.101
Fly
toxin transport GO:1901998 2 0.101
cellular biosynthetic process GO:0044249 286 0.096
Human Yeast Mouse
regulation of metabolic process GO:0019222 359 0.091
Human Yeast
programmed cell death GO:0012501 119 0.088
Worm
reproduction GO:0000003 40 0.087
Worm
meiotic nuclear division GO:0007126 4 0.085
response to hexose GO:0009746 3 0.085
ribonucleoside monophosphate catabolic process GO:0009158 4 0.083
response to glucose GO:0009749 3 0.076
regulation of gene expression GO:0010468 265 0.076
Human Yeast
regulation of apoptotic process GO:0042981 98 0.073
meiotic cell cycle process GO:1903046 3 0.073
blood vessel morphogenesis GO:0048514 216 0.065
cellular protein metabolic process GO:0044267 129 0.064
Human Yeast Mouse
regulation of cell shape GO:0008360 1 0.063
cell cycle process GO:0022402 53 0.062
Fly
cellular component movement GO:0006928 335 0.061
vasculature development GO:0001944 278 0.061
organic cyclic compound metabolic process GO:1901360 301 0.060
Yeast Mouse
positive regulation of biological process GO:0048518 253 0.060
Human Yeast
transmembrane transport GO:0055085 120 0.059
regulation of mrna processing GO:0050684 3 0.058
response to organic substance GO:0010033 153 0.055
protein stabilization GO:0050821 2 0.054
regulation of macromolecule metabolic process GO:0060255 317 0.054
Human Yeast
protein localization to nucleus GO:0034504 3 0.054
microtubule cytoskeleton organization involved in mitosis GO:1902850 1 0.053
protein metabolic process GO:0019538 183 0.052
Human Yeast Mouse
negative regulation of cellular catabolic process GO:0031330 3 0.050
organic substance biosynthetic process GO:1901576 289 0.050
Human Yeast Mouse
negative regulation of catabolic process GO:0009895 3 0.048
negative regulation of mrna metabolic process GO:1903312 3 0.048
rna polyadenylation GO:0043631 2 0.046
small molecule metabolic process GO:0044281 77 0.045
Yeast Mouse
metal ion transport GO:0030001 58 0.045
negative regulation of mrna catabolic process GO:1902373 2 0.043
interaction with host GO:0051701 4 0.043
positive regulation of mrna metabolic process GO:1903313 2 0.043
embryonic organ development GO:0048568 381 0.043
response to carbohydrate GO:0009743 3 0.042
protein complex subunit organization GO:0071822 46 0.041
Fly
cell proliferation GO:0008283 80 0.038
nitrogen compound metabolic process GO:0006807 319 0.038
Yeast Mouse
cell morphogenesis GO:0000902 289 0.036
tube morphogenesis GO:0035239 349 0.036
microtubule cytoskeleton organization GO:0000226 33 0.035
Fly
nucleobase containing compound metabolic process GO:0006139 274 0.034
Yeast Mouse
meiotic spindle organization GO:0000212 1 0.034
nucleic acid metabolic process GO:0090304 244 0.034
multicellular organism growth GO:0035264 4 0.034
positive regulation of neural precursor cell proliferation GO:2000179 1 0.034
phosphate containing compound metabolic process GO:0006796 108 0.033
Yeast Mouse
nuclear division GO:0000280 23 0.033
camera type eye development GO:0043010 222 0.033
eye development GO:0001654 277 0.032
cellular macromolecule biosynthetic process GO:0034645 224 0.032
Human Yeast Mouse
carbohydrate homeostasis GO:0033500 1 0.032
glucose homeostasis GO:0042593 1 0.032
cellular response to nutrient levels GO:0031669 2 0.032
establishment of protein localization to plasma membrane GO:0090002 1 0.032
heterocycle metabolic process GO:0046483 290 0.032
Yeast Mouse
cellular response to topologically incorrect protein GO:0035967 2 0.032
death GO:0016265 121 0.031
Worm
organelle assembly GO:0070925 110 0.031
macromolecular complex assembly GO:0065003 35 0.031
regulation of anatomical structure morphogenesis GO:0022603 130 0.031
aromatic compound catabolic process GO:0019439 15 0.030
Yeast Mouse
positive regulation of cellular process GO:0048522 201 0.030
Human Yeast
pancreas development GO:0031016 84 0.030
positive regulation of apoptotic process GO:0043065 29 0.030
positive regulation of catabolic process GO:0009896 4 0.029
purine ribonucleoside monophosphate catabolic process GO:0009169 4 0.029
gene expression GO:0010467 252 0.029
Human Yeast Mouse
negative regulation of metabolic process GO:0009892 86 0.028
positive regulation of mrna processing GO:0050685 1 0.028
spermatid development GO:0007286 2 0.027
spindle assembly GO:0051225 2 0.027
phosphorus metabolic process GO:0006793 109 0.026
Yeast Mouse
positive regulation of transport GO:0051050 2 0.026
rna localization GO:0006403 4 0.026
cellular nitrogen compound metabolic process GO:0034641 290 0.025
Yeast Mouse
protein complex biogenesis GO:0070271 30 0.025
positive regulation of apoptotic signaling pathway GO:2001235 1 0.024
growth GO:0040007 174 0.024
Worm
cellular component assembly GO:0022607 170 0.024
regulation of translation GO:0006417 3 0.023
Human Yeast
regulation of primary metabolic process GO:0080090 311 0.023
Human Yeast
positive regulation of programmed cell death GO:0043068 29 0.023
regulation of mrna catabolic process GO:0061013 3 0.023
negative regulation of phosphate metabolic process GO:0045936 13 0.023
guanosine containing compound metabolic process GO:1901068 4 0.023
Yeast Mouse
response to monosaccharide GO:0034284 3 0.023
pole plasm assembly GO:0007315 4 0.023
post embryonic morphogenesis GO:0009886 4 0.023
macromolecular complex subunit organization GO:0043933 74 0.022
Fly
regulation of biological quality GO:0065008 263 0.022
cytoskeleton organization GO:0007010 96 0.022
Fly
hatching GO:0035188 4 0.021
chemical homeostasis GO:0048878 49 0.021
establishment of localization GO:0051234 244 0.021
inorganic ion transmembrane transport GO:0098660 57 0.021
protein import GO:0017038 3 0.021
cellular response to external stimulus GO:0071496 2 0.020
protein localization to plasma membrane GO:0072659 1 0.020
nuclear import GO:0051170 3 0.020
regulation of cell proliferation involved in heart morphogenesis GO:2000136 2 0.020
spindle assembly involved in meiosis GO:0090306 1 0.020
cation transmembrane transport GO:0098655 65 0.020
spermatid differentiation GO:0048515 2 0.020
ribosomal small subunit biogenesis GO:0042274 2 0.020
regulation of molecular function GO:0065009 70 0.020
generation of neurons GO:0048699 385 0.020
nucleoside monophosphate catabolic process GO:0009125 4 0.020
reproductive process GO:0022414 40 0.020
Worm
posttranscriptional regulation of gene expression GO:0010608 14 0.020
Human Yeast
negative regulation of biological process GO:0048519 304 0.019
sexual reproduction GO:0019953 36 0.019
Worm
maintenance of location GO:0051235 4 0.019
endocytosis GO:0006897 16 0.019
rna catabolic process GO:0006401 7 0.019
positive regulation of cellular catabolic process GO:0031331 3 0.019
embryonic heart tube development GO:0035050 133 0.018
ossification GO:0001503 23 0.018
neurotransmitter secretion GO:0007269 2 0.018
head development GO:0060322 303 0.018
regulation of establishment of protein localization GO:0070201 4 0.018
regulation of cellular amino acid metabolic process GO:0006521 0 0.018
digestive tract morphogenesis GO:0048546 231 0.018
regulation of reproductive process GO:2000241 4 0.018
tissue remodeling GO:0048771 4 0.018
protein complex assembly GO:0006461 30 0.018
negative regulation of programmed cell death GO:0043069 58 0.017
somitogenesis GO:0001756 87 0.017
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 1 0.017
centrosome duplication GO:0051298 1 0.017
negative regulation of macromolecule metabolic process GO:0010605 76 0.017
purine ribonucleotide metabolic process GO:0009150 27 0.017
Yeast Mouse
mitotic nuclear division GO:0007067 18 0.017
negative regulation of cellular metabolic process GO:0031324 77 0.017
sensory organ development GO:0007423 393 0.017
nuclear transport GO:0051169 4 0.017
cellular response to organic substance GO:0071310 105 0.017
nucleobase containing compound catabolic process GO:0034655 15 0.017
Yeast Mouse
purine nucleoside monophosphate catabolic process GO:0009128 4 0.017
negative regulation of protein phosphorylation GO:0001933 4 0.016
mesenchymal cell proliferation GO:0010463 1 0.016
regulation of protein binding GO:0043393 3 0.016
mitotic cell cycle process GO:1903047 48 0.016
Fly
regulation of signal transduction GO:0009966 225 0.016
cellular amine metabolic process GO:0044106 2 0.016
regulation of intracellular protein transport GO:0033157 3 0.016
single organism transport GO:0044765 206 0.016
gastrulation GO:0007369 208 0.016
eye morphogenesis GO:0048592 144 0.015
negative regulation of apoptotic process GO:0043066 55 0.015
ribosome assembly GO:0042255 1 0.015
regulation of response to stimulus GO:0048583 269 0.015
negative regulation of cellular process GO:0048523 283 0.015
organelle organization GO:0006996 227 0.015
Fly
cellular amino acid metabolic process GO:0006520 7 0.015
interspecies interaction between organisms GO:0044419 4 0.015
nucleobase containing compound biosynthetic process GO:0034654 205 0.015
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.015
Human Yeast
vesicle mediated transport GO:0016192 22 0.015
ion transmembrane transport GO:0034220 91 0.015
response to chemical GO:0042221 320 0.015
homeostatic process GO:0042592 142 0.015
single organism organelle organization GO:1902589 199 0.015
Fly
muscle structure development GO:0061061 196 0.015
ribonucleotide metabolic process GO:0009259 27 0.015
Yeast Mouse
rna biosynthetic process GO:0032774 181 0.015
organic substance catabolic process GO:1901575 28 0.014
Yeast Mouse
actin filament based process GO:0030029 64 0.014
response to antibiotic GO:0046677 1 0.014
guanosine containing compound catabolic process GO:1901069 2 0.014
Yeast Mouse
regulation of signaling GO:0023051 235 0.014
nephron morphogenesis GO:0072028 2 0.014
embryonic skeletal system morphogenesis GO:0048704 93 0.014
rna 3 end processing GO:0031123 2 0.014
carboxylic acid metabolic process GO:0019752 22 0.014
protein targeting to nucleus GO:0044744 3 0.014
cellular component biogenesis GO:0044085 178 0.014
ion homeostasis GO:0050801 41 0.014
neurotransmitter transport GO:0006836 2 0.013
biosynthetic process GO:0009058 294 0.013
Human Yeast Mouse
regulation of protein metabolic process GO:0051246 56 0.013
Human Yeast
convergent extension involved in gastrulation GO:0060027 71 0.013
regulation of mrna 3 end processing GO:0031440 1 0.013
organelle fission GO:0048285 23 0.013
mrna stabilization GO:0048255 4 0.013
centrosome cycle GO:0007098 1 0.013
female meiotic division GO:0007143 2 0.013
mrna catabolic process GO:0006402 6 0.012
regulation of macromolecule biosynthetic process GO:0010556 225 0.012
Human Yeast
regulation of mesenchymal cell proliferation GO:0010464 1 0.012
cellular response to chemical stimulus GO:0070887 157 0.012
embryonic viscerocranium morphogenesis GO:0048703 52 0.012
atp catabolic process GO:0006200 4 0.012
oocyte anterior posterior axis specification GO:0007314 4 0.012
gene silencing by rna GO:0031047 4 0.012
ribonucleoside triphosphate biosynthetic process GO:0009201 2 0.012
blood vessel development GO:0001568 246 0.012
microtubule based process GO:0007017 60 0.012
Fly
ion transport GO:0006811 114 0.012
regulation of cellular ketone metabolic process GO:0010565 7 0.011
nucleocytoplasmic transport GO:0006913 4 0.011
negative regulation of translational initiation GO:0045947 1 0.011
lipid storage GO:0019915 1 0.011
regulation of protein catabolic process GO:0042176 1 0.011
digestive system development GO:0055123 289 0.011
nephron tubule morphogenesis GO:0072078 1 0.011
cellular response to extracellular stimulus GO:0031668 2 0.011
nucleoside phosphate metabolic process GO:0006753 28 0.011
Yeast Mouse
regulation of nucleocytoplasmic transport GO:0046822 2 0.011
cellular component morphogenesis GO:0032989 336 0.011
positive regulation of embryonic development GO:0040019 3 0.011
oxoacid metabolic process GO:0043436 31 0.010
regulation of binding GO:0051098 3 0.010
gamete generation GO:0007276 33 0.010
Worm
localization of cell GO:0051674 244 0.010
regulation of developmental process GO:0050793 247 0.010
aromatic compound biosynthetic process GO:0019438 217 0.010
negative regulation of protein kinase b signaling GO:0051898 2 0.010
regulation of protein targeting GO:1903533 2 0.010
locomotion GO:0040011 313 0.010
positive regulation of mesenchymal cell proliferation GO:0002053 1 0.010

eef2b disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.031
intestinal cancer DOID:10155 0 0.022
cancer DOID:162 0 0.022
large intestine cancer DOID:5672 0 0.022
disease of cellular proliferation DOID:14566 0 0.022
organ system cancer DOID:0050686 0 0.022
gastrointestinal system cancer DOID:3119 0 0.022
colorectal cancer DOID:9256 0 0.022
central nervous system disease DOID:331 0 0.016
neurodegenerative disease DOID:1289 0 0.016
nervous system disease DOID:863 0 0.016
immune system disease DOID:2914 0 0.013
hematopoietic system disease DOID:74 0 0.013