Danio rerio

0 known processes

ef1a

elongation factor 1-alpha

(Aliases: xx:tdsubc_2b3,tdsubc_2a3,chunp6927,eef1a,ik:tdsubc_2b3,wu:fi13b09,xx:tdsubc_2a3,ik:tdsubc_2a3,wu:fa91c07,wu:fa94b03,EFL1-alpha)

ef1a biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
regulation of biological quality GO:0065008 263 0.913
organic cyclic compound metabolic process GO:1901360 301 0.891
Worm
regulation of gene expression GO:0010468 265 0.890
positive regulation of biological process GO:0048518 253 0.848
negative regulation of gene expression GO:0010629 65 0.838
regulation of cellular metabolic process GO:0031323 320 0.828
immune response GO:0006955 28 0.819
nitrogen compound metabolic process GO:0006807 319 0.816
Worm
specification of symmetry GO:0009799 204 0.757
phosphorus metabolic process GO:0006793 109 0.726
Worm
positive regulation of cellular process GO:0048522 201 0.711
regulation of defense response GO:0031347 14 0.705
gene expression GO:0010467 252 0.682
regulation of translational initiation GO:0006446 1 0.660
response to organic substance GO:0010033 153 0.658
response to stress GO:0006950 263 0.657
regulation of metabolic process GO:0019222 359 0.648
positive regulation of cellular metabolic process GO:0031325 94 0.645
protein import GO:0017038 3 0.626
organic cyclic compound biosynthetic process GO:1901362 223 0.615
regulation of apoptotic process GO:0042981 98 0.611
nucleobase containing compound metabolic process GO:0006139 274 0.611
Worm
regulation of macromolecule metabolic process GO:0060255 317 0.599
rna metabolic process GO:0016070 219 0.579
regulation of proteolysis GO:0030162 24 0.576
pole plasm assembly GO:0007315 4 0.557
biosynthetic process GO:0009058 294 0.556
cellular nitrogen compound metabolic process GO:0034641 290 0.553
Worm
response to chemical GO:0042221 320 0.544
nucleic acid metabolic process GO:0090304 244 0.518
cellular aromatic compound metabolic process GO:0006725 295 0.497
Worm
negative regulation of cellular process GO:0048523 283 0.492
aromatic compound biosynthetic process GO:0019438 217 0.489
cellular response to external stimulus GO:0071496 2 0.488
translational initiation GO:0006413 3 0.488
regulation of cellular component organization GO:0051128 86 0.480
regulation of cell death GO:0010941 103 0.476
cellular response to organic cyclic compound GO:0071407 38 0.476
regulation of cellular biosynthetic process GO:0031326 245 0.473
negative regulation of biological process GO:0048519 304 0.462
larval development GO:0002164 2 0.451
Worm
head development GO:0060322 303 0.450
heterocycle metabolic process GO:0046483 290 0.449
Worm
ribonucleotide metabolic process GO:0009259 27 0.445
Worm
regulation of innate immune response GO:0045088 11 0.437
defense response GO:0006952 47 0.433
response to salt stress GO:0009651 10 0.421
response to organic cyclic compound GO:0014070 51 0.394
positive regulation of biosynthetic process GO:0009891 68 0.392
activation of immune response GO:0002253 9 0.391
blood vessel development GO:0001568 246 0.385
purine containing compound metabolic process GO:0072521 29 0.385
Worm
nucleoside monophosphate catabolic process GO:0009125 4 0.378
cytoskeleton dependent cytokinesis GO:0061640 3 0.362
ribose phosphate metabolic process GO:0019693 27 0.358
Worm
regulation of primary metabolic process GO:0080090 311 0.358
cellular biosynthetic process GO:0044249 286 0.358
response to cold GO:0009409 4 0.356
purine nucleoside monophosphate catabolic process GO:0009128 4 0.353
negative regulation of cell death GO:0060548 60 0.353
regulation of nitrogen compound metabolic process GO:0051171 251 0.313
negative regulation of apoptotic process GO:0043066 55 0.312
dicarboxylic acid metabolic process GO:0043648 1 0.312
type i interferon production GO:0032606 2 0.309
rna processing GO:0006396 25 0.306
nucleobase containing compound biosynthetic process GO:0034654 205 0.305
positive regulation of immune response GO:0050778 11 0.305
regulation of nucleocytoplasmic transport GO:0046822 2 0.305
endocardial cushion formation GO:0003272 2 0.303
protein localization to membrane GO:0072657 9 0.302
rna stabilization GO:0043489 4 0.296
eye development GO:0001654 277 0.286
organelle organization GO:0006996 227 0.285
mitotic cell cycle GO:0000278 64 0.284
cellular response to organic substance GO:0071310 105 0.277
cellular response to nutrient levels GO:0031669 2 0.276
positive regulation of translation GO:0045727 1 0.275
guanosine containing compound metabolic process GO:1901068 4 0.266
Worm
alternative mrna splicing via spliceosome GO:0000380 1 0.260
regulation of protein metabolic process GO:0051246 56 0.259
regulation of binding GO:0051098 3 0.259
apoptotic process GO:0006915 116 0.249
Worm
response to oxygen containing compound GO:1901700 55 0.248
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.246
cell morphogenesis involved in differentiation GO:0000904 195 0.243
embryonic organ development GO:0048568 381 0.242
rna localization GO:0006403 4 0.241
cellular macromolecule metabolic process GO:0044260 391 0.239
programmed cell death GO:0012501 119 0.237
Worm
response to abiotic stimulus GO:0009628 122 0.235
retina homeostasis GO:0001895 12 0.231
stem cell maintenance GO:0019827 4 0.230
response to external biotic stimulus GO:0043207 97 0.229
cellular component morphogenesis GO:0032989 336 0.228
response to antibiotic GO:0046677 1 0.226
small molecule metabolic process GO:0044281 77 0.223
Worm
negative regulation of translational initiation GO:0045947 1 0.221
negative regulation of nucleic acid templated transcription GO:1903507 45 0.221
heterocycle biosynthetic process GO:0018130 215 0.220
aromatic compound catabolic process GO:0019439 15 0.217
Worm
cellular macromolecule biosynthetic process GO:0034645 224 0.217
regulation of macromolecule biosynthetic process GO:0010556 225 0.217
regulation of anatomical structure morphogenesis GO:0022603 130 0.215
maintenance of location GO:0051235 4 0.209
cellular response to starvation GO:0009267 1 0.208
regulation of programmed cell death GO:0043067 101 0.208
negative regulation of protein phosphorylation GO:0001933 4 0.208
regionalization GO:0003002 274 0.204
innate immune response GO:0045087 13 0.200
purine nucleotide metabolic process GO:0006163 27 0.200
Worm
regulation of cellular amino acid metabolic process GO:0006521 0 0.199
negative regulation of protein maturation GO:1903318 10 0.199
single organism cellular localization GO:1902580 46 0.195
nucleobase containing compound catabolic process GO:0034655 15 0.192
Worm
dorsal ventral pattern formation GO:0009953 125 0.192
coagulation GO:0050817 13 0.192
negative regulation of cellular metabolic process GO:0031324 77 0.189
positive regulation of macromolecule metabolic process GO:0010604 93 0.189
response to biotic stimulus GO:0009607 97 0.186
cellular response to extracellular stimulus GO:0031668 2 0.182
oocyte anterior posterior axis specification GO:0007314 4 0.181
immune system development GO:0002520 191 0.181
positive regulation of transport GO:0051050 2 0.180
signal transduction GO:0007165 455 0.175
organic substance biosynthetic process GO:1901576 289 0.174
blood vessel morphogenesis GO:0048514 216 0.173
regulation of immune response GO:0050776 14 0.173
synaptic growth at neuromuscular junction GO:0051124 2 0.172
ion homeostasis GO:0050801 41 0.171
actin cytoskeleton organization GO:0030036 63 0.170
cellular modified amino acid metabolic process GO:0006575 3 0.169
cytokinesis GO:0000910 3 0.167
response to drug GO:0042493 3 0.164
gene silencing by rna GO:0031047 4 0.161
gland development GO:0048732 143 0.161
regulation of multicellular organismal development GO:2000026 223 0.160
purine ribonucleotide metabolic process GO:0009150 27 0.160
Worm
internal protein amino acid acetylation GO:0006475 2 0.159
regulation of cytoplasmic transport GO:1903649 4 0.157
response to endogenous stimulus GO:0009719 83 0.156
positive regulation of cellular biosynthetic process GO:0031328 68 0.156
positive regulation of cellular protein metabolic process GO:0032270 22 0.154
positive regulation of cellular component biogenesis GO:0044089 3 0.153
maternal determination of anterior posterior axis embryo GO:0008358 4 0.153
neuron differentiation GO:0030182 353 0.150
pancreas development GO:0031016 84 0.150
regulation of intracellular protein transport GO:0033157 3 0.147
macromolecular complex subunit organization GO:0043933 74 0.147
protein localization GO:0008104 40 0.147
mrna metabolic process GO:0016071 20 0.147
anterior posterior pattern specification GO:0009952 152 0.146
sensory organ development GO:0007423 393 0.145
establishment of protein localization to plasma membrane GO:0090002 1 0.145
negative regulation of cellular protein metabolic process GO:0032269 16 0.144
positive regulation of metabolic process GO:0009893 108 0.144
response to nitrogen compound GO:1901698 19 0.144
cellular response to chemical stimulus GO:0070887 157 0.142
regulation of cell development GO:0060284 100 0.142
zymogen activation GO:0031638 3 0.141
ribonucleoprotein complex assembly GO:0022618 5 0.140
cellular protein metabolic process GO:0044267 129 0.140
cellular response to biotic stimulus GO:0071216 3 0.139
positive regulation of response to stimulus GO:0048584 80 0.138
establishment of protein localization to organelle GO:0072594 4 0.138
single organism transport GO:0044765 206 0.136
organic acid metabolic process GO:0006082 31 0.136
carboxylic acid metabolic process GO:0019752 22 0.135
liver development GO:0001889 96 0.134
epithelial cell morphogenesis GO:0003382 2 0.133
regulation of response to stimulus GO:0048583 269 0.133
organonitrogen compound metabolic process GO:1901564 74 0.132
Worm
regulation of multicellular organismal process GO:0051239 277 0.132
response to oxidative stress GO:0006979 11 0.132
cellular response to topologically incorrect protein GO:0035967 2 0.131
negative regulation of nitrogen compound metabolic process GO:0051172 59 0.128
neurotransmitter transport GO:0006836 2 0.127
blood coagulation GO:0007596 12 0.127
negative regulation of macromolecule biosynthetic process GO:0010558 48 0.127
nuclear transport GO:0051169 4 0.126
phosphate containing compound metabolic process GO:0006796 108 0.126
Worm
negative regulation of cellular catabolic process GO:0031330 3 0.125
regulation of cellular protein metabolic process GO:0032268 52 0.123
death GO:0016265 121 0.123
Worm
protein localization to plasma membrane GO:0072659 1 0.122
cognition GO:0050890 1 0.122
positive regulation of phosphorus metabolic process GO:0010562 21 0.120
translation GO:0006412 5 0.119
mrna processing GO:0006397 14 0.117
response to nutrient levels GO:0031667 10 0.117
cellular response to cytokine stimulus GO:0071345 7 0.117
embryo development ending in birth or egg hatching GO:0009792 271 0.116
Worm
immune system process GO:0002376 241 0.116
cellular nitrogen compound biosynthetic process GO:0044271 218 0.115
central nervous system development GO:0007417 387 0.115
eye morphogenesis GO:0048592 144 0.115
guanosine containing compound catabolic process GO:1901069 2 0.115
Worm
negative regulation of catabolic process GO:0009895 3 0.115
regulation of translation GO:0006417 3 0.115
negative regulation of response to stimulus GO:0048585 104 0.114
macromolecule localization GO:0033036 54 0.114
mitochondrial transport GO:0006839 2 0.114
camera type eye development GO:0043010 222 0.114
purine ribonucleoside monophosphate catabolic process GO:0009169 4 0.113
reproduction GO:0000003 40 0.113
Worm
sensory organ morphogenesis GO:0090596 200 0.113
ribonucleoside monophosphate catabolic process GO:0009158 4 0.112
amine metabolic process GO:0009308 2 0.111
response to external stimulus GO:0009605 264 0.110
negative regulation of macromolecule metabolic process GO:0010605 76 0.110
cellular component assembly GO:0022607 170 0.110
cellular component biogenesis GO:0044085 178 0.110
protein localization to nucleus GO:0034504 3 0.109
response to temperature stimulus GO:0009266 15 0.109
positive regulation of cytokine production GO:0001819 2 0.108
cellular localization GO:0051641 97 0.108
cellular macromolecule catabolic process GO:0044265 12 0.108
cellular ketone metabolic process GO:0042180 11 0.107
response to other organism GO:0051707 97 0.106
positive regulation of lymphocyte mediated immunity GO:0002708 1 0.104
heterocycle catabolic process GO:0046700 15 0.103
Worm
cellular transition metal ion homeostasis GO:0046916 3 0.103
regulation of oxidative stress induced intrinsic apoptotic signaling pathway GO:1902175 2 0.103
mesenchyme development GO:0060485 127 0.103
negative regulation of oxidative stress induced intrinsic apoptotic signaling pathway GO:1902176 2 0.102
neuron projection morphogenesis GO:0048812 161 0.102
ribonucleoside metabolic process GO:0009119 11 0.102
Worm
response to wounding GO:0009611 116 0.101
organic substance transport GO:0071702 58 0.100
transcription from rna polymerase ii promoter GO:0006366 80 0.099
nucleocytoplasmic transport GO:0006913 4 0.097
regulation of epithelial cell proliferation GO:0050678 3 0.097
mrna stabilization GO:0048255 4 0.096
intracellular mrna localization GO:0008298 1 0.096
cytoplasm organization GO:0007028 4 0.095
nucleic acid templated transcription GO:0097659 181 0.095
establishment of localization in cell GO:0051649 77 0.094
hepaticobiliary system development GO:0061008 98 0.091
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.091
regulation of mrna splicing via spliceosome GO:0048024 3 0.091
cellular response to endogenous stimulus GO:0071495 68 0.091
single organism metabolic process GO:0044710 217 0.090
Worm
regulation of protein targeting GO:1903533 2 0.089
cellular amino acid metabolic process GO:0006520 7 0.089
carbohydrate derivative metabolic process GO:1901135 61 0.088
Worm
system process GO:0003008 185 0.088
wound healing GO:0042060 90 0.086
positive regulation of defense response to virus by host GO:0002230 0 0.086
response to decreased oxygen levels GO:0036293 25 0.085
oxoacid metabolic process GO:0043436 31 0.085
regulation of developmental process GO:0050793 247 0.083
negative regulation of multicellular organismal process GO:0051241 69 0.082
positive regulation of cell death GO:0010942 29 0.081
aging GO:0007568 2 0.080
Worm
regulation of biosynthetic process GO:0009889 250 0.080
blood circulation GO:0008015 87 0.080
muscle tissue development GO:0060537 110 0.079
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.078
regulation of signal transduction GO:0009966 225 0.078
actin filament based process GO:0030029 64 0.077
embryonic heart tube development GO:0035050 133 0.077
cellular protein catabolic process GO:0044257 4 0.076
homeostatic process GO:0042592 142 0.075
positive regulation of immune system process GO:0002684 17 0.074
3 utr mediated mrna stabilization GO:0070935 3 0.074
regulation of rna metabolic process GO:0051252 224 0.073
regulation of peptidase activity GO:0052547 23 0.072
positive regulation of nuclease activity GO:0032075 1 0.071
protein targeting to membrane GO:0006612 1 0.071
determination of heart left right asymmetry GO:0061371 117 0.070
innervation GO:0060384 3 0.070
regulation of cell morphogenesis GO:0022604 42 0.070
covalent chromatin modification GO:0016569 20 0.070
atp catabolic process GO:0006200 4 0.069
cellular amine metabolic process GO:0044106 2 0.069
cellular response to lipopolysaccharide GO:0071222 3 0.067
response to starvation GO:0042594 5 0.067
regulation of cellular amine metabolic process GO:0033238 0 0.067
positive regulation of proteolysis GO:0045862 10 0.066
negative regulation of protein processing GO:0010955 10 0.066
peptidyl serine modification GO:0018209 2 0.066
positive regulation of rna metabolic process GO:0051254 59 0.065
regulation of protein localization to nucleus GO:1900180 2 0.065
regulation of molecular function GO:0065009 70 0.064
angiogenesis GO:0001525 158 0.064
mitotic cell cycle process GO:1903047 48 0.064
macromolecule biosynthetic process GO:0009059 227 0.063
response to topologically incorrect protein GO:0035966 2 0.063
response to virus GO:0009615 21 0.063
positive regulation of programmed cell death GO:0043068 29 0.062
skeletal system development GO:0001501 181 0.062
positive regulation of apoptotic process GO:0043065 29 0.062
negative regulation of programmed cell death GO:0043069 58 0.062
proteolysis GO:0006508 38 0.062
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.062
intracellular transport GO:0046907 32 0.061
cellular response to molecule of bacterial origin GO:0071219 3 0.060
regulation of rho protein signal transduction GO:0035023 2 0.059
regulation of mrna processing GO:0050684 3 0.058
cell surface receptor signaling pathway GO:0007166 325 0.058
immune response activating signal transduction GO:0002757 5 0.058
telomere maintenance GO:0000723 1 0.058
spermatid differentiation GO:0048515 2 0.058
retina development in camera type eye GO:0060041 146 0.057
regulation of cellular ketone metabolic process GO:0010565 7 0.057
cellular response to decreased oxygen levels GO:0036294 1 0.057
positive regulation of cellular catabolic process GO:0031331 3 0.056
negative regulation of translation GO:0017148 1 0.056
single organism localization GO:1902578 225 0.056
spermatogenesis GO:0007283 7 0.056
response to carbohydrate GO:0009743 3 0.055
positive regulation of immune effector process GO:0002699 3 0.055
determination of bilateral symmetry GO:0009855 204 0.055
regulation of transcription from rna polymerase ii promoter in response to oxidative stress GO:0043619 0 0.055
rrna catabolic process GO:0016075 1 0.055
ion transport GO:0006811 114 0.055
heart morphogenesis GO:0003007 156 0.054
endoplasmic reticulum unfolded protein response GO:0030968 2 0.054
nucleoside catabolic process GO:0009164 7 0.054
Worm
oxidation reduction process GO:0055114 41 0.054
transport GO:0006810 220 0.054
negative regulation of metabolic process GO:0009892 86 0.054
neurotransmitter secretion GO:0007269 2 0.054
regulation of protein import into nucleus GO:0042306 2 0.053
cytokinetic process GO:0032506 2 0.053
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 1 0.053
macromolecule modification GO:0043412 111 0.052
hemostasis GO:0007599 13 0.052
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.052
regulation of nuclease activity GO:0032069 1 0.052
regulation of endopeptidase activity GO:0052548 23 0.051
cellular macromolecule localization GO:0070727 21 0.051
neural crest cell development GO:0014032 62 0.051
brain development GO:0007420 293 0.051
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.050
regulation of gene expression epigenetic GO:0040029 11 0.050
positive regulation of innate immune response GO:0045089 8 0.049
cellular component maintenance GO:0043954 3 0.049
regulation of protein catabolic process GO:0042176 1 0.049
positive regulation of cell cycle GO:0045787 3 0.049
vasculature development GO:0001944 278 0.048
positive regulation of signal transduction GO:0009967 56 0.048
negative regulation of developmental process GO:0051093 65 0.048
glomerulus vasculature development GO:0072012 2 0.047
skeletal system morphogenesis GO:0048705 102 0.047
fertilization GO:0009566 3 0.047
single organism organelle organization GO:1902589 199 0.047
negative regulation of cellular biosynthetic process GO:0031327 55 0.046
protein targeting to nucleus GO:0044744 3 0.046
establishment or maintenance of cell polarity GO:0007163 29 0.046
interaction with host GO:0051701 4 0.046
regulation of protein complex assembly GO:0043254 3 0.045
internal peptidyl lysine acetylation GO:0018393 2 0.044
locomotion GO:0040011 313 0.044
Worm
very long chain fatty acid biosynthetic process GO:0042761 4 0.044
cellular response to stress GO:0033554 62 0.044
regulation of inflammatory response GO:0050727 2 0.044
transcription dna templated GO:0006351 181 0.044
cellular protein localization GO:0034613 20 0.043
ncrna catabolic process GO:0034661 1 0.043
modification dependent protein catabolic process GO:0019941 3 0.043
regulation of cytokine production GO:0001817 3 0.043
response to monosaccharide GO:0034284 3 0.042
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.042
rna splicing via transesterification reactions with bulged adenosine as nucleophile GO:0000377 10 0.042
positive regulation of peptidase activity GO:0010952 10 0.042
regulation of actin filament based process GO:0032970 9 0.041
somitogenesis GO:0001756 87 0.041
response to amino acid GO:0043200 2 0.041
response to corticosteroid GO:0031960 1 0.041
fatty acid transport GO:0015908 1 0.041
negative regulation of proteolysis GO:0045861 10 0.041
developmental maturation GO:0021700 34 0.041
regulation of transcription dna templated GO:0006355 213 0.040
purine containing compound biosynthetic process GO:0072522 20 0.040
female gonad development GO:0008585 4 0.040
cellular component movement GO:0006928 335 0.040
tissue regeneration GO:0042246 74 0.040
modification by symbiont of host morphology or physiology GO:0044003 4 0.040
nucleotide biosynthetic process GO:0009165 21 0.039
regulation of protein maturation GO:1903317 10 0.039
regulation of nervous system development GO:0051960 90 0.039
single organism membrane organization GO:0044802 20 0.039
proteasomal protein catabolic process GO:0010498 2 0.039
neural crest cell differentiation GO:0014033 72 0.038
homophilic cell adhesion via plasma membrane adhesion molecules GO:0007156 4 0.038
regulation of establishment of protein localization GO:0070201 4 0.038
regulation of cellular response to oxidative stress GO:1900407 2 0.038
positive regulation of gene expression GO:0010628 71 0.038
negative regulation of biosynthetic process GO:0009890 55 0.038
circadian sleep wake cycle sleep GO:0050802 1 0.038
axis specification GO:0009798 43 0.038
regulation of chronic inflammatory response GO:0002676 1 0.038
response to heat GO:0009408 6 0.038
gastrulation GO:0007369 208 0.038
positive regulation of cytoskeleton organization GO:0051495 3 0.038
cell morphogenesis GO:0000902 289 0.038
regulation of anatomical structure size GO:0090066 33 0.037
mitochondrion organization GO:0007005 4 0.037
response to hexose GO:0009746 3 0.037
establishment of protein localization to membrane GO:0090150 3 0.037
peptidyl serine phosphorylation GO:0018105 1 0.037
biological adhesion GO:0022610 40 0.036
neuron recognition GO:0008038 18 0.036
positive regulation of protein metabolic process GO:0051247 23 0.036
protein maturation GO:0051604 12 0.036
regulation of synapse organization GO:0050807 3 0.036
nucleobase containing small molecule metabolic process GO:0055086 32 0.036
Worm
epithelial tube morphogenesis GO:0060562 148 0.036
anatomical structure homeostasis GO:0060249 36 0.036
ameboidal type cell migration GO:0001667 143 0.036
muscle organ development GO:0007517 101 0.035
behavior GO:0007610 74 0.035
regulation of protein ubiquitination GO:0031396 3 0.035
regulation of cell differentiation GO:0045595 142 0.035
regulation of response to biotic stimulus GO:0002831 2 0.034
regulation of mrna stability GO:0043488 4 0.034
positive regulation of nucleobase containing compound metabolic process GO:0045935 69 0.034
lipid storage GO:0019915 1 0.034
modification dependent macromolecule catabolic process GO:0043632 3 0.034
tube morphogenesis GO:0035239 349 0.034
renal system vasculature development GO:0061437 2 0.034
negative regulation of cellular macromolecule biosynthetic process GO:2000113 48 0.034
beta amyloid metabolic process GO:0050435 1 0.034
t cell differentiation in thymus GO:0033077 6 0.034
apoptotic process involved in development GO:1902742 2 0.034
nucleotide metabolic process GO:0009117 28 0.033
Worm
regulation of immune system process GO:0002682 34 0.033
regulation of protein binding GO:0043393 3 0.033
ribonucleotide biosynthetic process GO:0009260 20 0.033
regulation of defense response to virus GO:0050688 2 0.033
cellular response to fatty acid GO:0071398 3 0.033
spermatid development GO:0007286 2 0.033
rna catabolic process GO:0006401 7 0.033
meiotic nuclear division GO:0007126 4 0.032
multi organism process GO:0051704 134 0.032
Worm
skeletal muscle tissue development GO:0007519 67 0.032
chemical homeostasis GO:0048878 49 0.032
hemopoiesis GO:0030097 183 0.032
multicellular organism reproduction GO:0032504 35 0.032
Worm
negative regulation of rna metabolic process GO:0051253 48 0.032
membrane organization GO:0061024 21 0.032
odontogenesis of dentin containing tooth GO:0042475 1 0.032
multicellular organism growth GO:0035264 4 0.031
cell projection organization GO:0030030 284 0.031
i kappab kinase nf kappab signaling GO:0007249 4 0.031
response to acid chemical GO:0001101 17 0.031
regulation of intracellular signal transduction GO:1902531 57 0.031
regulation of localization GO:0032879 104 0.031
detection of mechanical stimulus GO:0050982 11 0.031
muscle system process GO:0003012 20 0.031
cellular nitrogen compound catabolic process GO:0044270 15 0.031
Worm
single organism nuclear import GO:1902593 3 0.030
skeletal muscle organ development GO:0060538 78 0.030
positive regulation of multi organism process GO:0043902 3 0.030
chromosome organization involved in meiosis GO:0070192 1 0.030
antibacterial humoral response GO:0019731 2 0.030
axon development GO:0061564 166 0.030
cellular response to oxygen levels GO:0071453 1 0.030
cellular response to toxic substance GO:0097237 1 0.029
positive regulation of macromolecule biosynthetic process GO:0010557 59 0.029
establishment of rna localization GO:0051236 3 0.029
vesicle mediated transport GO:0016192 22 0.029
cellular response to unfolded protein GO:0034620 2 0.029
axon guidance GO:0007411 86 0.029
protein import into nucleus GO:0006606 3 0.029
response to lipopolysaccharide GO:0032496 13 0.029
somatic stem cell maintenance GO:0035019 1 0.029
epithelial cell differentiation GO:0030855 116 0.028
inorganic cation transmembrane transport GO:0098662 50 0.028
response to osmotic stress GO:0006970 11 0.028
positive regulation of exocytosis GO:0045921 1 0.028
positive regulation of secretion by cell GO:1903532 1 0.027

ef1a disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.353
nervous system disease DOID:863 0 0.301
disease of metabolism DOID:0014667 0 0.156
inherited metabolic disorder DOID:655 0 0.156
myopathy DOID:423 0 0.095
muscular disease DOID:0080000 0 0.095
heart disease DOID:114 0 0.095
cardiomyopathy DOID:0050700 0 0.095
intrinsic cardiomyopathy DOID:0060036 0 0.095
cardiovascular system disease DOID:1287 0 0.095
musculoskeletal system disease DOID:17 0 0.095
muscle tissue disease DOID:66 0 0.095
central nervous system disease DOID:331 0 0.064
tauopathy DOID:680 0 0.064
neurodegenerative disease DOID:1289 0 0.064
colon carcinoma DOID:1520 0 0.038
large intestine cancer DOID:5672 0 0.038
colon cancer DOID:219 0 0.038
gastrointestinal system cancer DOID:3119 0 0.038
intestinal cancer DOID:10155 0 0.038
cancer DOID:162 0 0.038
disease of cellular proliferation DOID:14566 0 0.038
organ system cancer DOID:0050686 0 0.038
colorectal cancer DOID:9256 0 0.038
lipid storage disease DOID:9455 0 0.028
lysosomal storage disease DOID:3211 0 0.028