Danio rerio

27 known processes

egr1

early growth response 1

(Aliases: wu:fj64b05,krox-24,krox24,wu:fq25f01)

egr1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
positive regulation of biological process GO:0048518 253 0.994
Human Mouse Rat
chordate embryonic development GO:0043009 271 0.977
regulation of gene expression GO:0010468 265 0.972
Human Mouse Rat
embryo development ending in birth or egg hatching GO:0009792 271 0.955
nucleobase containing compound biosynthetic process GO:0034654 205 0.949
Human Mouse Rat
gene expression GO:0010467 252 0.937
Human Mouse Rat
response to external stimulus GO:0009605 264 0.935
Rat
heterocycle biosynthetic process GO:0018130 215 0.934
Human Mouse Rat
regulation of nucleic acid templated transcription GO:1903506 213 0.929
Human Mouse Rat
cellular biosynthetic process GO:0044249 286 0.924
Human Mouse Rat
rna biosynthetic process GO:0032774 181 0.913
Human Mouse Rat
response to chemical GO:0042221 320 0.907
Human Mouse Rat
regulation of cellular biosynthetic process GO:0031326 245 0.907
Human Mouse Rat
skeletal system development GO:0001501 181 0.902
rhombomere boundary formation GO:0021654 10 0.885
Zebrafish
organic cyclic compound metabolic process GO:1901360 301 0.881
Human Mouse Rat
regulation of metabolic process GO:0019222 359 0.865
Human Mouse Rat Worm
negative regulation of map kinase activity GO:0043407 2 0.864
Worm
regionalization GO:0003002 274 0.856
embryonic skeletal system development GO:0048706 97 0.844
biosynthetic process GO:0009058 294 0.825
Human Mouse Rat
cellular macromolecule biosynthetic process GO:0034645 224 0.812
Human Mouse Rat
regulation of biological quality GO:0065008 263 0.809
Zebrafish Rat
regulation of macromolecule metabolic process GO:0060255 317 0.799
Human Mouse Rat Worm
posterior lateral line nerve glial cell development GO:0048941 5 0.799
Zebrafish
negative regulation of cellular process GO:0048523 283 0.798
Mouse Worm
regulation of rna metabolic process GO:0051252 224 0.795
Human Mouse Rat
organic cyclic compound biosynthetic process GO:1901362 223 0.784
Human Mouse Rat
head development GO:0060322 303 0.783
Zebrafish
brain development GO:0007420 293 0.768
Zebrafish
nuclear transport GO:0051169 4 0.763
heterocycle metabolic process GO:0046483 290 0.759
Human Mouse Rat
negative regulation of response to stimulus GO:0048585 104 0.758
Mouse Worm
cell surface receptor signaling pathway GO:0007166 325 0.758
Human Mouse
central nervous system development GO:0007417 387 0.751
Zebrafish Rat Fly
hematopoietic or lymphoid organ development GO:0048534 191 0.750
Mouse
digestive system development GO:0055123 289 0.745
inner ear development GO:0048839 126 0.745
cellular nitrogen compound metabolic process GO:0034641 290 0.739
Human Mouse Rat
cell motility GO:0048870 244 0.738
Fly
positive regulation of cellular process GO:0048522 201 0.737
Human Mouse Rat
signal transduction GO:0007165 455 0.720
Human Mouse Worm
negative regulation of protein kinase activity GO:0006469 4 0.714
Worm
gastrulation GO:0007369 208 0.695
ameboidal type cell migration GO:0001667 143 0.693
Fly
eye development GO:0001654 277 0.691
regulation of cellular metabolic process GO:0031323 320 0.690
Human Mouse Rat Worm
positive regulation of biosynthetic process GO:0009891 68 0.689
Human Mouse Rat
positive regulation of gene expression GO:0010628 71 0.679
Human Mouse Rat
hindbrain development GO:0030902 91 0.679
Zebrafish
macromolecule biosynthetic process GO:0009059 227 0.667
Human Mouse Rat
negative regulation of biosynthetic process GO:0009890 55 0.667
Mouse
cognition GO:0050890 1 0.664
Rat
mechanosensory lateral line system development GO:0048881 49 0.661
Zebrafish
chemosensory behavior GO:0007635 1 0.655
regulation of macromolecule biosynthetic process GO:0010556 225 0.653
Human Mouse Rat
generation of neurons GO:0048699 385 0.646
regulation of rna biosynthetic process GO:2001141 213 0.638
Human Mouse Rat
digestive tract morphogenesis GO:0048546 231 0.638
posterior lateral line system development GO:0048915 46 0.637
Zebrafish
sensory organ morphogenesis GO:0090596 200 0.634
regulation of primary metabolic process GO:0080090 311 0.621
Human Mouse Rat Worm
transcription dna templated GO:0006351 181 0.618
Human Mouse Rat
nucleic acid templated transcription GO:0097659 181 0.598
Human Mouse Rat
rhombomere development GO:0021546 19 0.586
Zebrafish
positive regulation of macromolecule biosynthetic process GO:0010557 59 0.583
Human Mouse Rat
cell morphogenesis involved in differentiation GO:0000904 195 0.574
Zebrafish
system process GO:0003008 185 0.571
Zebrafish Rat
neuron differentiation GO:0030182 353 0.567
cellular nitrogen compound biosynthetic process GO:0044271 218 0.565
Human Mouse Rat
cellular aromatic compound metabolic process GO:0006725 295 0.559
Human Mouse Rat
positive regulation of cell adhesion GO:0045785 1 0.558
single organism transport GO:0044765 206 0.554
Fly
aromatic compound biosynthetic process GO:0019438 217 0.551
Human Mouse Rat
sensory perception of chemical stimulus GO:0007606 3 0.548
immune system process GO:0002376 241 0.540
Mouse
negative regulation of signaling GO:0023057 96 0.540
Mouse Worm
neuron development GO:0048666 262 0.537
embryonic organ morphogenesis GO:0048562 274 0.531
locomotion GO:0040011 313 0.526
Fly
positive regulation of nucleic acid templated transcription GO:1903508 57 0.524
Human Mouse Rat
sensory organ development GO:0007423 393 0.518
ear development GO:0043583 127 0.517
glomerular epithelial cell fate commitment GO:0072314 4 0.514
Zebrafish
embryonic skeletal system morphogenesis GO:0048704 93 0.514
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 68 0.507
Mouse
positive regulation of macromolecule metabolic process GO:0010604 93 0.497
Human Mouse Rat
regulation of developmental process GO:0050793 247 0.487
Rat
apoptotic process GO:0006915 116 0.485
Mouse Rat
larval heart development GO:0007508 2 0.472
mesoderm development GO:0007498 88 0.469
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.465
Human Mouse Rat
cellular component biogenesis GO:0044085 178 0.463
response to wounding GO:0009611 116 0.460
cell projection organization GO:0030030 284 0.456
embryonic cranial skeleton morphogenesis GO:0048701 90 0.455
negative regulation of macromolecule metabolic process GO:0010605 76 0.455
Mouse Worm
protein localization to nucleus GO:0034504 3 0.453
posterior lateral line nerve glial cell morphogenesis involved in differentiation GO:0048942 5 0.448
Zebrafish
negative regulation of signal transduction GO:0009968 94 0.441
Mouse Worm
regulation of neuronal synaptic plasticity GO:0048168 1 0.439
Rat
anterior posterior pattern specification GO:0009952 152 0.439
neural crest cell development GO:0014032 62 0.423
lateral line system development GO:0048925 76 0.417
Zebrafish
blood vessel morphogenesis GO:0048514 216 0.416
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.414
Human Mouse Rat
cellular component morphogenesis GO:0032989 336 0.411
Zebrafish
epithelial cell fate commitment GO:0072148 11 0.408
Zebrafish
regulation of signaling GO:0023051 235 0.395
Mouse Rat Worm
negative regulation of nucleobase containing compound metabolic process GO:0045934 59 0.395
Mouse
enzyme linked receptor protein signaling pathway GO:0007167 106 0.391
Mouse
formation of primary germ layer GO:0001704 62 0.389
striated muscle tissue development GO:0014706 110 0.381
Mouse
single organism metabolic process GO:0044710 217 0.379
Worm
blood vessel development GO:0001568 246 0.376
Rat
response to ketone GO:1901654 1 0.374
positive regulation of cell death GO:0010942 29 0.370
Rat
nucleocytoplasmic transport GO:0006913 4 0.360
nucleic acid metabolic process GO:0090304 244 0.358
Human Mouse Rat
facial nerve morphogenesis GO:0021610 1 0.353
embryonic organ development GO:0048568 381 0.352
gland development GO:0048732 143 0.351
Zebrafish
nitrogen compound metabolic process GO:0006807 319 0.347
Human Mouse Rat
posterior lateral line nerve development GO:0048918 8 0.347
Zebrafish
protein localization GO:0008104 40 0.346
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.344
regulation of peptidase activity GO:0052547 23 0.342
negative regulation of cell communication GO:0010648 96 0.340
Mouse Worm
cell migration involved in gastrulation GO:0042074 79 0.335
tube morphogenesis GO:0035239 349 0.334
cell recognition GO:0008037 19 0.333
camera type eye development GO:0043010 222 0.333
negative regulation of macromolecule biosynthetic process GO:0010558 48 0.330
Mouse
retina morphogenesis in camera type eye GO:0060042 79 0.329
organic substance biosynthetic process GO:1901576 289 0.328
Human Mouse Rat
response to abiotic stimulus GO:0009628 122 0.328
Mouse Rat
negative regulation of biological process GO:0048519 304 0.326
Mouse Worm
establishment of localization in cell GO:0051649 77 0.323
axon ensheathment GO:0008366 18 0.322
Zebrafish
ensheathment of neurons GO:0007272 18 0.321
Zebrafish
reproduction GO:0000003 40 0.319
Worm
multi organism reproductive process GO:0044703 36 0.318
Worm
cellular macromolecule metabolic process GO:0044260 391 0.316
Human Mouse Rat Worm
response to drug GO:0042493 3 0.315
Rat
cell migration GO:0016477 237 0.301
Fly
regulation of synaptic plasticity GO:0048167 1 0.301
Rat
entrainment of circadian clock by photoperiod GO:0043153 1 0.297
cartilage development GO:0051216 96 0.291
single organismal cell cell adhesion GO:0016337 29 0.290
negative regulation of kinase activity GO:0033673 4 0.288
Worm
heart morphogenesis GO:0003007 156 0.287
nucleobase containing compound metabolic process GO:0006139 274 0.287
Human Mouse Rat
myelination GO:0042552 18 0.285
Zebrafish
convergent extension GO:0060026 118 0.283
positive regulation of rna biosynthetic process GO:1902680 57 0.282
Human Mouse Rat
digestive tract development GO:0048565 265 0.281
rhombomere 5 development GO:0021571 4 0.281
positive regulation of transcription dna templated GO:0045893 57 0.280
Human Mouse Rat
negative regulation of epithelial cell migration GO:0010633 1 0.277
hemopoiesis GO:0030097 183 0.274
Mouse
regulation of biosynthetic process GO:0009889 250 0.274
Human Mouse Rat
negative regulation of cellular macromolecule biosynthetic process GO:2000113 48 0.266
Mouse
multicellular organism growth GO:0035264 4 0.266
multi organism process GO:0051704 134 0.263
Worm
regulation of cellular protein metabolic process GO:0032268 52 0.263
Human Worm
establishment of localization GO:0051234 244 0.262
Fly
rna metabolic process GO:0016070 219 0.261
Human Mouse Rat
cellular carbohydrate metabolic process GO:0044262 4 0.261
oocyte maturation GO:0001556 4 0.260
Worm
neuron projection morphogenesis GO:0048812 161 0.259
regulation of transcription from rna polymerase ii promoter GO:0006357 114 0.256
Human Mouse Rat
antimicrobial humoral response GO:0019730 2 0.256
regulation of anatomical structure morphogenesis GO:0022603 130 0.255
hormone transport GO:0009914 2 0.254
muscle structure development GO:0061061 196 0.253
Mouse Fly
rhombomere 5 morphogenesis GO:0021664 1 0.251
female gamete generation GO:0007292 14 0.250
Worm
rhombomere morphogenesis GO:0021593 17 0.244
Zebrafish
meiotic nuclear division GO:0007126 4 0.244
negative regulation of phosphate metabolic process GO:0045936 13 0.241
Worm
positive regulation of programmed cell death GO:0043068 29 0.241
Rat
response to stress GO:0006950 263 0.240
Mouse Rat
cell death GO:0008219 121 0.234
Mouse Rat
positive regulation of cellular biosynthetic process GO:0031328 68 0.229
Human Mouse Rat
positive regulation of apoptotic process GO:0043065 29 0.229
Rat
regulation of cell shape GO:0008360 1 0.226
cell proliferation GO:0008283 80 0.226
Rat
dendrite guidance GO:0070983 0 0.224
forebrain development GO:0030900 96 0.222
programmed cell death GO:0012501 119 0.221
Mouse Rat
cellular response to chemical stimulus GO:0070887 157 0.220
Human Mouse Rat
cellular response to growth factor stimulus GO:0071363 39 0.218
Rat
cell adhesion GO:0007155 40 0.215
angiogenesis GO:0001525 158 0.215
regulation of photoreceptor cell differentiation GO:0046532 2 0.214
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.212
Human Mouse Rat
transport GO:0006810 220 0.211
Fly
developmental growth GO:0048589 166 0.209
myelination of posterior lateral line nerve axons GO:0048932 5 0.208
Zebrafish
transcription from rna polymerase ii promoter GO:0006366 80 0.207
Human Mouse Rat
cell cell signaling GO:0007267 52 0.206
Rat
protein targeting to nucleus GO:0044744 3 0.204
myelination of lateral line nerve axons GO:0048897 5 0.204
Zebrafish
regulation of molecular function GO:0065009 70 0.203
Worm
response to organic substance GO:0010033 153 0.203
Human Mouse Rat
innervation GO:0060384 3 0.197
response to growth factor GO:0070848 39 0.197
Rat
multicellular organism reproduction GO:0032504 35 0.196
Worm
developmental process involved in reproduction GO:0003006 27 0.194
Worm
formation of anatomical boundary GO:0048859 14 0.194
Zebrafish
positive regulation of cellular component biogenesis GO:0044089 3 0.193
epithelial cell differentiation GO:0030855 116 0.192
Zebrafish
multicellular organismal reproductive process GO:0048609 35 0.192
Worm
cell part morphogenesis GO:0032990 246 0.190
positive regulation of transport GO:0051050 2 0.188
cell fate commitment GO:0045165 99 0.187
Zebrafish
neuron fate determination GO:0048664 2 0.185
cellular component movement GO:0006928 335 0.185
Fly
photoreceptor cell development GO:0042461 40 0.183
pronephric nephron development GO:0039019 14 0.182
Zebrafish
germ cell development GO:0007281 22 0.180
Worm
neuron projection development GO:0031175 180 0.179
localization of cell GO:0051674 244 0.178
Fly
somite development GO:0061053 96 0.178
single organism cell adhesion GO:0098602 29 0.177
rhythmic behavior GO:0007622 5 0.174
regulation of response to stimulus GO:0048583 269 0.171
Mouse Worm
cardiocyte differentiation GO:0035051 44 0.169
cellular response to external stimulus GO:0071496 2 0.167
Rat
otic vesicle morphogenesis GO:0071600 34 0.167
negative regulation of protein serine threonine kinase activity GO:0071901 2 0.166
Worm
transmission of nerve impulse GO:0019226 19 0.166
Zebrafish
phagocytosis GO:0006909 3 0.165
Fly
cell migration involved in vasculogenesis GO:0035441 1 0.165
glial cell development GO:0021782 20 0.164
Zebrafish
stem cell differentiation GO:0048863 117 0.163
protein import into nucleus GO:0006606 3 0.163
negative regulation of transcription dna templated GO:0045892 45 0.162
Mouse
artery development GO:0060840 22 0.162
actin filament based process GO:0030029 64 0.162
larval development GO:0002164 2 0.161
embryonic viscerocranium morphogenesis GO:0048703 52 0.161
regulation of signal transduction GO:0009966 225 0.159
Mouse Worm
regulation of multicellular organismal process GO:0051239 277 0.159
Rat Worm
myeloid cell differentiation GO:0030099 86 0.158
somatic muscle development GO:0007525 4 0.157
Fly
cellular response to hormone stimulus GO:0032870 39 0.156
Rat
positive regulation of developmental process GO:0051094 50 0.155
Rat
regulation of transcription dna templated GO:0006355 213 0.155
Human Mouse Rat
regulation of multicellular organismal development GO:2000026 223 0.154
Rat
phosphorylation GO:0016310 69 0.151
Worm
eye morphogenesis GO:0048592 144 0.151
kidney development GO:0001822 92 0.150
Zebrafish Rat
positive regulation of nucleobase containing compound metabolic process GO:0045935 69 0.150
Human Mouse Rat
biological adhesion GO:0022610 40 0.149
neuron projection guidance GO:0097485 86 0.148
negative regulation of metabolic process GO:0009892 86 0.148
Mouse Worm
neuronal action potential GO:0019228 18 0.146
Zebrafish
wound healing GO:0042060 90 0.145
pronephros development GO:0048793 69 0.144
Zebrafish
somitogenesis GO:0001756 87 0.144
intracellular steroid hormone receptor signaling pathway GO:0030518 5 0.144
endoderm development GO:0007492 49 0.143
heart development GO:0007507 313 0.142
intracellular signal transduction GO:0035556 85 0.142
Worm
positive regulation of rna metabolic process GO:0051254 59 0.141
Human Mouse Rat
segmentation GO:0035282 97 0.138
macromolecule localization GO:0033036 54 0.138
rhombomere formation GO:0021594 12 0.135
Zebrafish
nitrogen compound transport GO:0071705 23 0.135
cardiogenic plate morphogenesis GO:0003142 1 0.135
response to light stimulus GO:0009416 46 0.135
regulation of localization GO:0032879 104 0.134
branchiomotor neuron axon guidance GO:0021785 1 0.134
cell fate commitment involved in formation of primary germ layer GO:0060795 26 0.133
regulation of cell communication GO:0010646 232 0.132
Mouse Rat Worm
regulation of membrane potential GO:0042391 23 0.130
Zebrafish
phosphorus metabolic process GO:0006793 109 0.129
Worm
hormone secretion GO:0046879 2 0.129
facial nerve development GO:0021561 3 0.128
tissue migration GO:0090130 37 0.127
Fly
positive regulation of cell differentiation GO:0045597 30 0.126
regulation of cell death GO:0010941 103 0.125
Mouse Rat
reproductive process GO:0022414 40 0.125
Worm
mesenchyme development GO:0060485 127 0.125
cell substrate junction assembly GO:0007044 2 0.125
apoptotic signaling pathway GO:0097190 23 0.125
venous blood vessel development GO:0060841 9 0.123
response to temperature stimulus GO:0009266 15 0.123
morphogenesis of an epithelium GO:0002009 333 0.122
anatomical structure arrangement GO:0048532 2 0.121
stem cell division GO:0017145 1 0.121
muscle organ development GO:0007517 101 0.120
Mouse Fly
epiboly GO:0090504 41 0.119
dorsal ventral pattern formation GO:0009953 125 0.118
macromolecule modification GO:0043412 111 0.118
Human Worm
amino acid transport GO:0006865 2 0.118
retina development in camera type eye GO:0060041 146 0.117
aging GO:0007568 2 0.117
single organism localization GO:1902578 225 0.117
Fly
regulation of synapse organization GO:0050807 3 0.113
eye photoreceptor cell development GO:0042462 30 0.112
intracellular transport GO:0046907 32 0.112
mesoderm morphogenesis GO:0048332 51 0.111
response to organic cyclic compound GO:0014070 51 0.110
Rat
skeletal system morphogenesis GO:0048705 102 0.110
photoreceptor cell differentiation GO:0046530 55 0.110
negative regulation of protein phosphorylation GO:0001933 4 0.109
Worm
intrahepatic bile duct development GO:0035622 11 0.108
regulation of response to stress GO:0080134 36 0.108
regulation of protein import into nucleus GO:0042306 2 0.108
negative regulation of rna metabolic process GO:0051253 48 0.108
Mouse
regulation of cell differentiation GO:0045595 142 0.107
regulation of reproductive process GO:2000241 4 0.107
Worm
regulation of nitrogen compound metabolic process GO:0051171 251 0.107
Human Mouse Rat
mesoderm formation GO:0001707 43 0.107
regulation of catalytic activity GO:0050790 55 0.106
Worm
cellular response to organic substance GO:0071310 105 0.106
Human Mouse Rat
neural retina development GO:0003407 49 0.104
cardiac cell fate commitment GO:0060911 1 0.104
cellular component assembly GO:0022607 170 0.103
renal system development GO:0072001 94 0.103
Zebrafish Rat
response to endogenous stimulus GO:0009719 83 0.103
Mouse Rat
cell cycle GO:0007049 93 0.102
embryonic heart tube development GO:0035050 133 0.101
negative regulation of nucleic acid templated transcription GO:1903507 45 0.099
Mouse
regulation of programmed cell death GO:0043067 101 0.098
Mouse Rat
organic substance transport GO:0071702 58 0.097
monoamine transport GO:0015844 1 0.097
single organism reproductive process GO:0044702 40 0.097
Worm
fin development GO:0033333 77 0.097
post embryonic organ morphogenesis GO:0048563 1 0.096
regulation of protein transport GO:0051223 3 0.096
cell substrate adhesion GO:0031589 4 0.095
chemotaxis GO:0006935 104 0.094
positive regulation of metabolic process GO:0009893 108 0.094
Human Mouse Rat
cell morphogenesis GO:0000902 289 0.093
Zebrafish
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 50 0.093
astrocyte differentiation GO:0048708 1 0.092
macromolecular complex subunit organization GO:0043933 74 0.091
erythrocyte homeostasis GO:0034101 55 0.089
cardiac cell development GO:0055006 21 0.089
regulation of cysteine type endopeptidase activity GO:2000116 21 0.087
sexual reproduction GO:0019953 36 0.087
Worm
morphogenesis of an epithelial sheet GO:0002011 49 0.086
positive regulation of secretion GO:0051047 1 0.085
carboxylic acid metabolic process GO:0019752 22 0.085
forebrain cell migration GO:0021885 1 0.084
regulation of intracellular protein transport GO:0033157 3 0.084
cellular response to endogenous stimulus GO:0071495 68 0.084
Rat
gtp metabolic process GO:0046039 4 0.083
embryonic heart tube morphogenesis GO:0003143 108 0.083
olfactory lobe development GO:0021988 4 0.083
negative regulation of gliogenesis GO:0014014 1 0.082
peripheral nervous system development GO:0007422 55 0.082
regulation of establishment of protein localization GO:0070201 4 0.082
endodermal cell differentiation GO:0035987 19 0.082
regulation of multicellular organism growth GO:0040014 4 0.082
negative regulation of phosphorus metabolic process GO:0010563 13 0.082
Worm
oocyte development GO:0048599 14 0.081
Worm
positive regulation of multicellular organismal process GO:0051240 52 0.081
Rat
cardiac muscle cell development GO:0055013 20 0.080
positive regulation of secretion by cell GO:1903532 1 0.080
cranial suture morphogenesis GO:0060363 1 0.080
regulation of hormone secretion GO:0046883 2 0.078
endocardium formation GO:0060214 1 0.078
action potential GO:0001508 19 0.078
Zebrafish
peptide transport GO:0015833 1 0.078
fin regeneration GO:0031101 51 0.078
inositol lipid mediated signaling GO:0048017 2 0.077
neurotransmitter transport GO:0006836 2 0.076
determination of intestine left right asymmetry GO:0071908 2 0.076
regulation of nervous system development GO:0051960 90 0.075
skeletal muscle organ development GO:0060538 78 0.075
Mouse
cellular ketone metabolic process GO:0042180 11 0.074
cellular response to nutrient levels GO:0031669 2 0.074
regulation of cell adhesion GO:0030155 15 0.074
locomotor rhythm GO:0045475 3 0.074
neuron neuron synaptic transmission GO:0007270 1 0.073
ectoderm development GO:0007398 9 0.073
Fly
regeneration GO:0031099 91 0.073
connective tissue development GO:0061448 99 0.073
Rat
motor neuron axon guidance GO:0008045 23 0.072
regulation of protein localization to nucleus GO:1900180 2 0.072
negative regulation of nitrogen compound metabolic process GO:0051172 59 0.072
Mouse
reflex GO:0060004 2 0.071
kupffer s vesicle development GO:0070121 50 0.071
synaptic growth at neuromuscular junction GO:0051124 2 0.070
taxis GO:0042330 109 0.070
organelle organization GO:0006996 227 0.070
negative regulation of axon guidance GO:1902668 1 0.070
neuromuscular synaptic transmission GO:0007274 2 0.069
negative regulation of protein metabolic process GO:0051248 16 0.068
Worm
regulation of cell cell adhesion GO:0022407 13 0.068
regulation of extrinsic apoptotic signaling pathway GO:2001236 3 0.068
regulation of glial cell differentiation GO:0045685 4 0.068
glucose homeostasis GO:0042593 1 0.067
post embryonic organ development GO:0048569 4 0.067
negative regulation of cellular metabolic process GO:0031324 77 0.066
Mouse Worm
negative regulation of catalytic activity GO:0043086 21 0.066
Worm
cell type specific apoptotic process GO:0097285 22 0.065
Rat
negative regulation of cell death GO:0060548 60 0.065
otic placode formation GO:0043049 23 0.065
medial fin development GO:0033338 16 0.065
female gonad development GO:0008585 4 0.065
embryonic skeletal joint development GO:0072498 3 0.064
intracellular estrogen receptor signaling pathway GO:0030520 3 0.064
odontogenesis of dentin containing tooth GO:0042475 1 0.064
female sex differentiation GO:0046660 4 0.064
adult behavior GO:0030534 2 0.064
catechol containing compound biosynthetic process GO:0009713 2 0.064
response to decreased oxygen levels GO:0036293 25 0.064
Mouse Rat
protein metabolic process GO:0019538 183 0.063
Human Worm
synaptic target recognition GO:0008039 1 0.063
regulation of cell development GO:0060284 100 0.063
lateral line nerve glial cell morphogenesis involved in differentiation GO:0048938 5 0.062
Zebrafish
organelle fusion GO:0048284 3 0.061
nuclear export GO:0051168 1 0.061
synaptic transmission GO:0007268 35 0.061
Rat
cell migration to the midline involved in heart development GO:0003318 12 0.060
phosphate containing compound metabolic process GO:0006796 108 0.059
Worm
regulation of proteolysis GO:0030162 24 0.059
axon guidance GO:0007411 86 0.059
entrainment of circadian clock GO:0009649 2 0.059
defense response GO:0006952 47 0.058
erythrocyte differentiation GO:0030218 54 0.058
hard palate development GO:0060022 4 0.058
gastrulation with mouth forming second GO:0001702 44 0.057
axonogenesis involved in innervation GO:0060385 1 0.057
negative regulation of chemotaxis GO:0050922 4 0.057
cellular amine metabolic process GO:0044106 2 0.057
stem cell development GO:0048864 82 0.056
oogenesis GO:0048477 14 0.056
Worm
central nervous system neuron differentiation GO:0021953 74 0.056
regulation of circadian sleep wake cycle GO:0042749 1 0.056
small molecule metabolic process GO:0044281 77 0.056
growth GO:0040007 174 0.055
cranial nerve development GO:0021545 42 0.055
Zebrafish
regulation of circadian rhythm GO:0042752 4 0.055
regulation of protein metabolic process GO:0051246 56 0.055
Human Worm
regulation of vasculature development GO:1901342 33 0.054
Rat
oxoacid metabolic process GO:0043436 31 0.054
response to inorganic substance GO:0010035 38 0.053
homeostatic process GO:0042592 142 0.053
cellular protein localization GO:0034613 20 0.053
axon development GO:0061564 166 0.053
negative regulation of programmed cell death GO:0043069 58 0.053
regulation of stem cell proliferation GO:0072091 2 0.053
olfactory bulb development GO:0021772 4 0.053
regulation of protein phosphorylation GO:0001932 18 0.053
Worm
endocardium development GO:0003157 9 0.052
negative regulation of reproductive process GO:2000242 3 0.052
Worm
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 20 0.052
regulation of heart growth GO:0060420 2 0.052
establishment of protein localization to organelle GO:0072594 4 0.052
palate development GO:0060021 8 0.051
extrinsic apoptotic signaling pathway GO:0097191 3 0.051
cell fate specification GO:0001708 68 0.051
multicellular organismal signaling GO:0035637 22 0.051
Zebrafish
positive regulation of neuron apoptotic process GO:0043525 1 0.050
Rat
fin morphogenesis GO:0033334 53 0.050
smad protein complex assembly GO:0007183 1 0.050
camera type eye morphogenesis GO:0048593 108 0.050
cell projection morphogenesis GO:0048858 244 0.050
nerve development GO:0021675 45 0.049
Zebrafish
viral process GO:0016032 1 0.049
development of primary female sexual characteristics GO:0046545 4 0.049
single organism nuclear import GO:1902593 3 0.049
determination of digestive tract left right asymmetry GO:0071907 10 0.049
response to uv GO:0009411 3 0.049
spindle organization GO:0007051 5 0.049
negative regulation of intracellular signal transduction GO:1902532 22 0.049
Worm
negative regulation of intrinsic apoptotic signaling pathway GO:2001243 8 0.048
symbiosis encompassing mutualism through parasitism GO:0044403 4 0.048
regulation of hydrolase activity GO:0051336 28 0.048
serotonin biosynthetic process GO:0042427 1 0.048
leukocyte differentiation GO:0002521 25 0.048
Mouse
regulation of meiotic cell cycle GO:0051445 1 0.048
glial cell differentiation GO:0010001 42 0.048
Zebrafish Rat
protein import GO:0017038 3 0.047
post embryonic morphogenesis GO:0009886 4 0.047
nuclear import GO:0051170 3 0.047
organ regeneration GO:0031100 1 0.046
negative regulation of multicellular organismal process GO:0051241 69 0.046
Worm
forebrain neuron development GO:0021884 7 0.046
regulation of cell morphogenesis GO:0022604 42 0.045
response to food GO:0032094 1 0.045
morphogenesis of a branching structure GO:0001763 21 0.045
regulation of mononuclear cell migration GO:0071675 1 0.045
regulation of nucleocytoplasmic transport GO:0046822 2 0.045
chemical homeostasis GO:0048878 49 0.045
locomotory behavior GO:0007626 34 0.044

egr1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
charcot marie tooth disease type 4 DOID:0050541 0 0.344
neuromuscular disease DOID:440 0 0.344
disease of anatomical entity DOID:7 0 0.344
charcot marie tooth disease DOID:10595 0 0.344
nervous system disease DOID:863 0 0.344
neuropathy DOID:870 0 0.344
disease of metabolism DOID:0014667 0 0.059