Danio rerio

68 known processes

ehmt2

euchromatic histone-lysine N-methyltransferase 2

(Aliases: wu:fb63b12,wu:fu47h08,ehmt2a,g9a,bat8)

ehmt2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
histone methylation GO:0016571 13 0.613
protein methylation GO:0006479 13 0.607
histone lysine methylation GO:0034968 12 0.597
peptidyl lysine methylation GO:0018022 3 0.579
protein alkylation GO:0008213 13 0.499
macromolecule methylation GO:0043414 19 0.463
organelle organization GO:0006996 227 0.390
meiotic nuclear division GO:0007126 4 0.375
methylation GO:0032259 22 0.349
cellular macromolecule metabolic process GO:0044260 391 0.338
nitrogen compound metabolic process GO:0006807 319 0.330
heterocycle metabolic process GO:0046483 290 0.302
histone h3 k36 methylation GO:0010452 2 0.300
histone h3 k9 modification GO:0061647 5 0.289
chromatin modification GO:0016568 21 0.283
cellular nitrogen compound metabolic process GO:0034641 290 0.273
nucleic acid metabolic process GO:0090304 244 0.263
regulation of gene expression GO:0010468 265 0.259
regulation of transcription dna templated GO:0006355 213 0.231
embryo development ending in birth or egg hatching GO:0009792 271 0.208
regulation of primary metabolic process GO:0080090 311 0.205
nucleobase containing compound metabolic process GO:0006139 274 0.201
larval development GO:0002164 2 0.198
nucleobase containing compound biosynthetic process GO:0034654 205 0.198
regulation of nitrogen compound metabolic process GO:0051171 251 0.197
histone h3 k4 methylation GO:0051568 2 0.192
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.184
heterocycle biosynthetic process GO:0018130 215 0.184
single organism organelle organization GO:1902589 199 0.182
histone h3 k9 methylation GO:0051567 5 0.181
single organism metabolic process GO:0044710 217 0.175
regulation of cellular metabolic process GO:0031323 320 0.173
cellular aromatic compound metabolic process GO:0006725 295 0.169
regulation of metabolic process GO:0019222 359 0.168
histone h4 k20 methylation GO:0034770 2 0.154
organic cyclic compound metabolic process GO:1901360 301 0.150
cell projection organization GO:0030030 284 0.145
chromosome organization GO:0051276 31 0.145
peptidyl lysine trimethylation GO:0018023 1 0.140
regulation of macromolecule metabolic process GO:0060255 317 0.140
negative regulation of biological process GO:0048519 304 0.139
regulation of cellular biosynthetic process GO:0031326 245 0.138
neuron differentiation GO:0030182 353 0.130
regulation of meiotic cell cycle GO:0051445 1 0.130
protein modification process GO:0036211 100 0.128
negative regulation of cellular process GO:0048523 283 0.128
cell projection morphogenesis GO:0048858 244 0.120
establishment of localization GO:0051234 244 0.117
chordate embryonic development GO:0043009 271 0.115
protein metabolic process GO:0019538 183 0.114
cellular component morphogenesis GO:0032989 336 0.111
cellular protein modification process GO:0006464 100 0.111
gastrulation GO:0007369 208 0.111
histone modification GO:0016570 20 0.109
regulation of macromolecule biosynthetic process GO:0010556 225 0.108
rna metabolic process GO:0016070 219 0.107
gene expression GO:0010467 252 0.105
aromatic compound biosynthetic process GO:0019438 217 0.103
macromolecule modification GO:0043412 111 0.102
macromolecule biosynthetic process GO:0009059 227 0.100
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.097
meiosis ii GO:0007135 1 0.095
generation of neurons GO:0048699 385 0.094
regulation of rna metabolic process GO:0051252 224 0.094
cell morphogenesis GO:0000902 289 0.092
macromolecular complex subunit organization GO:0043933 74 0.092
cellular protein metabolic process GO:0044267 129 0.092
development of primary female sexual characteristics GO:0046545 4 0.090
organic substance biosynthetic process GO:1901576 289 0.089
brain development GO:0007420 293 0.088
regulation of biosynthetic process GO:0009889 250 0.087
rna biosynthetic process GO:0032774 181 0.087
multi organism process GO:0051704 134 0.084
regulation of organelle assembly GO:1902115 4 0.083
central nervous system development GO:0007417 387 0.082
covalent chromatin modification GO:0016569 20 0.076
biosynthetic process GO:0009058 294 0.075
cell part morphogenesis GO:0032990 246 0.073
meiotic cell cycle process GO:1903046 3 0.069
heart development GO:0007507 313 0.069
neuron projection morphogenesis GO:0048812 161 0.069
regulation of establishment of protein localization GO:0070201 4 0.068
transcription dna templated GO:0006351 181 0.067
multicellular organismal reproductive process GO:0048609 35 0.065
mitotic cell cycle process GO:1903047 48 0.065
cellular process involved in reproduction in multicellular organism GO:0022412 28 0.065
female sex differentiation GO:0046660 4 0.061
regulation of protein import into nucleus GO:0042306 2 0.060
female gonad development GO:0008585 4 0.060
nuclear transport GO:0051169 4 0.060
multicellular organism reproduction GO:0032504 35 0.058
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.058
digestive system development GO:0055123 289 0.057
establishment of protein localization to organelle GO:0072594 4 0.057
immune system process GO:0002376 241 0.057
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.055
cellular nitrogen compound biosynthetic process GO:0044271 218 0.055
chromosome organization involved in meiosis GO:0070192 1 0.055
cellular macromolecule biosynthetic process GO:0034645 224 0.055
cell cycle GO:0007049 93 0.055
neuron projection development GO:0031175 180 0.055
nucleocytoplasmic transport GO:0006913 4 0.051
axonogenesis GO:0007409 152 0.050
regulation of rna biosynthetic process GO:2001141 213 0.050
transport GO:0006810 220 0.050
determination of bilateral symmetry GO:0009855 204 0.048
regionalization GO:0003002 274 0.047
reproduction GO:0000003 40 0.046
regulation of nucleocytoplasmic transport GO:0046822 2 0.046
regulation of protein localization to nucleus GO:1900180 2 0.045
regulation of protein transport GO:0051223 3 0.045
single organism nuclear import GO:1902593 3 0.045
cell morphogenesis involved in differentiation GO:0000904 195 0.045
meiotic chromosome segregation GO:0045132 3 0.045
regulation of intracellular protein transport GO:0033157 3 0.044
organelle assembly GO:0070925 110 0.043
stem cell maintenance GO:0019827 4 0.043
regulation of cytoplasmic transport GO:1903649 4 0.042
head development GO:0060322 303 0.041
nucleic acid templated transcription GO:0097659 181 0.041
specification of symmetry GO:0009799 204 0.041
axon development GO:0061564 166 0.041
protein import into nucleus GO:0006606 3 0.040
cellular biosynthetic process GO:0044249 286 0.040
response to stress GO:0006950 263 0.040
cellular component biogenesis GO:0044085 178 0.040
nuclear import GO:0051170 3 0.039
protein targeting to nucleus GO:0044744 3 0.039
cytoskeleton organization GO:0007010 96 0.038
protein localization to nucleus GO:0034504 3 0.038
positive regulation of jun kinase activity GO:0043507 2 0.037
rna localization GO:0006403 4 0.037
organelle fission GO:0048285 23 0.037
gamete generation GO:0007276 33 0.037
sexual reproduction GO:0019953 36 0.036
embryonic organ development GO:0048568 381 0.036
regulation of gene expression epigenetic GO:0040029 11 0.035
intracellular signal transduction GO:0035556 85 0.035
nuclear division GO:0000280 23 0.034
microtubule based process GO:0007017 60 0.034
germ cell development GO:0007281 22 0.034
proteasomal protein catabolic process GO:0010498 2 0.034
negative regulation of macromolecule metabolic process GO:0010605 76 0.034
spindle assembly GO:0051225 2 0.033
pancreas development GO:0031016 84 0.033
vasculature development GO:0001944 278 0.033
neuron development GO:0048666 262 0.033
multicellular organism growth GO:0035264 4 0.033
negative regulation of metabolic process GO:0009892 86 0.033
regulation of cellular amine metabolic process GO:0033238 0 0.031
regulation of response to stimulus GO:0048583 269 0.031
positive regulation of map kinase activity GO:0043406 3 0.031
protein import GO:0017038 3 0.031
b cell mediated immunity GO:0019724 3 0.031
sensory organ development GO:0007423 393 0.030
locomotion GO:0040011 313 0.030
phosphate containing compound metabolic process GO:0006796 108 0.030
cell cycle process GO:0022402 53 0.030
digestive tract development GO:0048565 265 0.029
multi organism reproductive process GO:0044703 36 0.029
response to chemical GO:0042221 320 0.029
regulation of protein targeting GO:1903533 2 0.029
regulation of histone methylation GO:0031060 3 0.029
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.029
regulation of nucleic acid templated transcription GO:1903506 213 0.029
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.029
organic cyclic compound biosynthetic process GO:1901362 223 0.028
negative regulation of transcription dna templated GO:0045892 45 0.028
developmental process involved in reproduction GO:0003006 27 0.028
positive regulation of stress activated protein kinase signaling cascade GO:0070304 3 0.028
death GO:0016265 121 0.028
microtubule organizing center organization GO:0031023 1 0.028
programmed cell death GO:0012501 119 0.027
ribonucleoside monophosphate catabolic process GO:0009158 4 0.027
cellular response to external stimulus GO:0071496 2 0.027
somatic cell dna recombination GO:0016444 1 0.027
dna alkylation GO:0006305 8 0.026
cellular response to nutrient levels GO:0031669 2 0.026
apoptotic process GO:0006915 116 0.025
positive regulation of transport GO:0051050 2 0.025
positive regulation of dna metabolic process GO:0051054 1 0.025
carboxylic acid metabolic process GO:0019752 22 0.025
positive regulation of cellular process GO:0048522 201 0.025
positive regulation of cellular amine metabolic process GO:0033240 0 0.025
regulation of cellular amino acid metabolic process GO:0006521 0 0.025
muscle structure development GO:0061061 196 0.025
aging GO:0007568 2 0.024
immunoglobulin mediated immune response GO:0016064 3 0.024
fertilization GO:0009566 3 0.024
nucleoside monophosphate catabolic process GO:0009125 4 0.024
cellular component assembly involved in morphogenesis GO:0010927 107 0.024
immune system development GO:0002520 191 0.024
maintenance of location GO:0051235 4 0.024
male meiosis GO:0007140 2 0.024
single organism reproductive process GO:0044702 40 0.024
regulation of cellular ketone metabolic process GO:0010565 7 0.024
cellular component assembly GO:0022607 170 0.023
digestive tract morphogenesis GO:0048546 231 0.023
negative regulation of protein phosphorylation GO:0001933 4 0.023
meiotic cell cycle GO:0051321 5 0.023
amine metabolic process GO:0009308 2 0.023
regulation of dna recombination GO:0000018 2 0.023
regulation of multicellular organism growth GO:0040014 4 0.023
gene silencing GO:0016458 4 0.023
blood vessel morphogenesis GO:0048514 216 0.023
regulation of cellular protein catabolic process GO:1903362 1 0.022
eye morphogenesis GO:0048592 144 0.022
cilium organization GO:0044782 71 0.022
negative regulation of nucleocytoplasmic transport GO:0046823 2 0.022
negative regulation of nucleobase containing compound metabolic process GO:0045934 59 0.022
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 1 0.022
response to external stimulus GO:0009605 264 0.022
dna modification GO:0006304 8 0.021
positive regulation of biological process GO:0048518 253 0.021
oxoacid metabolic process GO:0043436 31 0.021
response to corticosteroid GO:0031960 1 0.021
reproductive process GO:0022414 40 0.021
translational initiation GO:0006413 3 0.021
cellular response to chemical stimulus GO:0070887 157 0.021
organic acid metabolic process GO:0006082 31 0.021
signal transduction GO:0007165 455 0.021
cellular amino acid metabolic process GO:0006520 7 0.021
positive regulation of chromatin modification GO:1903310 1 0.021
negative regulation of chromosome organization GO:2001251 1 0.021
negative regulation of cytoplasmic transport GO:1903650 2 0.021
modification dependent protein catabolic process GO:0019941 3 0.020
negative regulation of myeloid leukocyte differentiation GO:0002762 1 0.020
positive regulation of cellular component biogenesis GO:0044089 3 0.020
phosphorus metabolic process GO:0006793 109 0.020
connective tissue development GO:0061448 99 0.020
regulation of protein complex assembly GO:0043254 3 0.020
positive regulation of jnk cascade GO:0046330 3 0.020
regulation of establishment of planar polarity GO:0090175 4 0.020
central nervous system neuron differentiation GO:0021953 74 0.019
anterior posterior pattern specification GO:0009952 152 0.019
cilium assembly GO:0042384 58 0.019
regulation of transcription from rna polymerase ii promoter GO:0006357 114 0.019
localization of cell GO:0051674 244 0.019
regulation of dendrite morphogenesis GO:0048814 3 0.019
homeostatic process GO:0042592 142 0.019
regulation of localization GO:0032879 104 0.019
negative regulation of catabolic process GO:0009895 3 0.019
negative regulation of dna metabolic process GO:0051053 4 0.019
regulation of response to extracellular stimulus GO:0032104 1 0.019
response to nutrient GO:0007584 3 0.019
response to monosaccharide GO:0034284 3 0.018
single organism localization GO:1902578 225 0.018
regulation of cellular component organization GO:0051128 86 0.018
small molecule metabolic process GO:0044281 77 0.018
regulation of organelle organization GO:0033043 29 0.018
regulation of nucleoside metabolic process GO:0009118 2 0.018
heart morphogenesis GO:0003007 156 0.018
positive regulation of cell cycle GO:0045787 3 0.018
cellular response to stress GO:0033554 62 0.018
negative regulation of cellular metabolic process GO:0031324 77 0.018
cellular response to starvation GO:0009267 1 0.018
stem cell division GO:0017145 1 0.018
skeletal system development GO:0001501 181 0.018
regulation of mrna splicing via spliceosome GO:0048024 3 0.018
muscle organ development GO:0007517 101 0.017
peptidyl serine phosphorylation GO:0018105 1 0.017
protein polyubiquitination GO:0000209 4 0.017
taxis GO:0042330 109 0.017
nuclear envelope organization GO:0006998 2 0.017
regulation of multicellular organismal process GO:0051239 277 0.017
exocrine pancreas development GO:0031017 28 0.017
forebrain regionalization GO:0021871 4 0.017
dna methylation or demethylation GO:0044728 8 0.017
hematopoietic or lymphoid organ development GO:0048534 191 0.017
b cell activation GO:0042113 2 0.017
blood vessel development GO:0001568 246 0.017
regulation of oocyte development GO:0060281 3 0.016
regulation of chromosome segregation GO:0051983 1 0.016
cellular ketone metabolic process GO:0042180 11 0.016
negative regulation of gene expression GO:0010629 65 0.016
embryonic organ morphogenesis GO:0048562 274 0.016
negative regulation of intracellular transport GO:0032387 3 0.016
telomere organization GO:0032200 1 0.016
immunoglobulin production GO:0002377 1 0.016
phosphorylation GO:0016310 69 0.016
chromatin organization GO:0006325 22 0.016
positive regulation of stress activated mapk cascade GO:0032874 3 0.016
alternative mrna splicing via spliceosome GO:0000380 1 0.016
protein stabilization GO:0050821 2 0.016
response to organic substance GO:0010033 153 0.016
mitotic cell cycle GO:0000278 64 0.016
negative regulation of kinase activity GO:0033673 4 0.016
positive regulation of cellular catabolic process GO:0031331 3 0.015
microtubule cytoskeleton organization involved in mitosis GO:1902850 1 0.015
positive regulation of catabolic process GO:0009896 4 0.015
meiosis i GO:0007127 1 0.015
synaptic target recognition GO:0008039 1 0.015
regulation of stem cell differentiation GO:2000736 4 0.015
cardiac atrium morphogenesis GO:0003209 2 0.015
negative regulation of macromolecule biosynthetic process GO:0010558 48 0.015
negative regulation of cellular biosynthetic process GO:0031327 55 0.015
meiotic spindle organization GO:0000212 1 0.015
polarized epithelial cell differentiation GO:0030859 4 0.015
angiogenesis GO:0001525 158 0.015
microtubule cytoskeleton organization GO:0000226 33 0.015
sensory organ morphogenesis GO:0090596 200 0.015
response to drug GO:0042493 3 0.015
cellular response to organic substance GO:0071310 105 0.015
eye development GO:0001654 277 0.015
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 2 0.015
centrosome organization GO:0051297 1 0.015
production of molecular mediator of immune response GO:0002440 2 0.015
regulation of biological quality GO:0065008 263 0.015
regulation of cell differentiation GO:0045595 142 0.014
regulation of jun kinase activity GO:0043506 3 0.014
wnt signaling pathway planar cell polarity pathway GO:0060071 4 0.014
negative regulation of defense response GO:0031348 2 0.014
cartilage development GO:0051216 96 0.014
positive regulation of histone modification GO:0031058 1 0.014
regulation of cellular protein metabolic process GO:0032268 52 0.014
negative regulation of epithelial cell proliferation GO:0050680 1 0.014
negative regulation of histone modification GO:0031057 1 0.014
cell substrate adhesion GO:0031589 4 0.014
tube morphogenesis GO:0035239 349 0.014
regulation of circadian rhythm GO:0042752 4 0.014
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 4 0.014
single organism cellular localization GO:1902580 46 0.014
stem cell proliferation GO:0072089 4 0.014
morphogenesis of an epithelium GO:0002009 333 0.013
regulation of protein metabolic process GO:0051246 56 0.013
response to abiotic stimulus GO:0009628 122 0.013
growth GO:0040007 174 0.013
lipid storage GO:0019915 1 0.013
embryonic heart tube morphogenesis GO:0003143 108 0.013
organonitrogen compound metabolic process GO:1901564 74 0.013
regulation of signaling GO:0023051 235 0.013
regulation of reproductive process GO:2000241 4 0.013
positive regulation of cell substrate adhesion GO:0010811 1 0.013
negative regulation of protein localization to nucleus GO:1900181 2 0.013
cellular response to extracellular stimulus GO:0031668 2 0.013
regulation of developmental process GO:0050793 247 0.013
regulation of protein catabolic process GO:0042176 1 0.013
negative regulation of protein kinase activity GO:0006469 4 0.013
determination of left right symmetry GO:0007368 179 0.013
positive regulation of biosynthetic process GO:0009891 68 0.012
atp catabolic process GO:0006200 4 0.012
regulation of response to nutrient levels GO:0032107 1 0.012
response to ketone GO:1901654 1 0.012
cell projection assembly GO:0030031 64 0.012
negative regulation of cellular catabolic process GO:0031330 3 0.012
heart looping GO:0001947 94 0.012
cellular component movement GO:0006928 335 0.012
cellular response to radiation GO:0071478 4 0.012
response to endogenous stimulus GO:0009719 83 0.012
cell migration GO:0016477 237 0.012
negative chemotaxis GO:0050919 1 0.012
regulation of molecular function GO:0065009 70 0.012
regulation of purine nucleotide catabolic process GO:0033121 2 0.012
regulation of anatomical structure morphogenesis GO:0022603 130 0.012
ubiquitin dependent protein catabolic process GO:0006511 3 0.012
negative regulation of cellular macromolecule biosynthetic process GO:2000113 48 0.012
sister chromatid cohesion GO:0007062 2 0.012
germ line stem cell division GO:0042078 1 0.012
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.012
regulation of response to cytokine stimulus GO:0060759 3 0.012
regulation of cell communication GO:0010646 232 0.012
regulation of transcription elongation from rna polymerase ii promoter GO:0034243 3 0.012
response to glucocorticoid GO:0051384 1 0.012
neural retina development GO:0003407 49 0.012
response to carbohydrate GO:0009743 3 0.012
photoreceptor cell differentiation GO:0046530 55 0.012
peptidyl lysine dimethylation GO:0018027 1 0.012
mesenchyme development GO:0060485 127 0.011
gtp catabolic process GO:0006184 2 0.011
mitotic dna damage checkpoint GO:0044773 4 0.011
peptidyl amino acid modification GO:0018193 16 0.011
dna methylation GO:0006306 8 0.011
dna metabolic process GO:0006259 27 0.011
regulation of muscle contraction GO:0006937 3 0.011
cilium morphogenesis GO:0060271 85 0.011
macromolecular complex assembly GO:0065003 35 0.011
neuroblast differentiation GO:0014016 1 0.011
camera type eye development GO:0043010 222 0.011
hemopoiesis GO:0030097 183 0.011
negative regulation of protein transport GO:0051224 3 0.011
negative regulation of rna biosynthetic process GO:1902679 45 0.011
macroautophagy GO:0016236 1 0.011
regulation of translational initiation GO:0006446 1 0.011
dna methylation on cytosine GO:0032776 3 0.011
regulation of dna methylation GO:0044030 5 0.011
oocyte maturation GO:0001556 4 0.011
photoreceptor cell development GO:0042461 40 0.011
cell death GO:0008219 121 0.011
axon guidance GO:0007411 86 0.011
regulation of epithelial cell proliferation GO:0050678 3 0.011
negative regulation of nitrogen compound metabolic process GO:0051172 59 0.011
regulation of cell development GO:0060284 100 0.011
response to amphetamine GO:0001975 1 0.011
negative regulation of intracellular protein transport GO:0090317 3 0.011
determination of heart left right asymmetry GO:0061371 117 0.011
negative regulation of nucleic acid templated transcription GO:1903507 45 0.011
peptidyl serine modification GO:0018209 2 0.011
regulation of multicellular organismal development GO:2000026 223 0.010
establishment of localization in cell GO:0051649 77 0.010
g1 s transition of mitotic cell cycle GO:0000082 1 0.010
intracellular mrna localization GO:0008298 1 0.010
somatic stem cell maintenance GO:0035019 1 0.010
spermatid development GO:0007286 2 0.010
guanosine containing compound catabolic process GO:1901069 2 0.010
nuclear export GO:0051168 1 0.010
regulation of protein ubiquitination GO:0031396 3 0.010
gtp metabolic process GO:0046039 4 0.010
negative regulation of nuclear division GO:0051784 3 0.010
activation of mapk activity GO:0000187 3 0.010
negative regulation of response to stimulus GO:0048585 104 0.010
stem cell differentiation GO:0048863 117 0.010
double strand break repair GO:0006302 3 0.010
adult behavior GO:0030534 2 0.010
cellular response to dna damage stimulus GO:0006974 24 0.010
regulation of dendrite development GO:0050773 3 0.010
purine ribonucleoside monophosphate catabolic process GO:0009169 4 0.010

ehmt2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
cancer DOID:162 0 0.035
disease of cellular proliferation DOID:14566 0 0.035
organ system cancer DOID:0050686 0 0.032
large intestine cancer DOID:5672 0 0.011
gastrointestinal system cancer DOID:3119 0 0.011
intestinal cancer DOID:10155 0 0.011
disease of anatomical entity DOID:7 0 0.011
nervous system disease DOID:863 0 0.011