Danio rerio

0 known processes

eif2s1

eukaryotic translation initiation factor 2, subunit 1 alpha

(Aliases: eif2,wu:fb19d01,fb19d01,MGC56347)

eif2s1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
larval development GO:0002164 2 0.889
Worm
embryo development ending in birth or egg hatching GO:0009792 271 0.571
Worm
regulation of multicellular organismal process GO:0051239 277 0.399
nitrogen compound metabolic process GO:0006807 319 0.275
regulation of biological quality GO:0065008 263 0.269
aging GO:0007568 2 0.248
cellular component assembly GO:0022607 170 0.207
macromolecule biosynthetic process GO:0009059 227 0.202
Human Mouse
central nervous system development GO:0007417 387 0.163
positive regulation of biological process GO:0048518 253 0.158
organelle organization GO:0006996 227 0.158
cellular component biogenesis GO:0044085 178 0.155
gamete generation GO:0007276 33 0.142
multi organism reproductive process GO:0044703 36 0.141
cellular macromolecule biosynthetic process GO:0034645 224 0.135
Human Mouse
head development GO:0060322 303 0.131
cellular biosynthetic process GO:0044249 286 0.127
Human Mouse
cellular process involved in reproduction in multicellular organism GO:0022412 28 0.123
nucleic acid metabolic process GO:0090304 244 0.120
multi organism process GO:0051704 134 0.113
organic cyclic compound metabolic process GO:1901360 301 0.108
locomotion GO:0040011 313 0.106
cellular nitrogen compound metabolic process GO:0034641 290 0.103
ribosomal small subunit biogenesis GO:0042274 2 0.103
positive regulation of developmental process GO:0051094 50 0.102
biosynthetic process GO:0009058 294 0.102
Human Mouse
organelle assembly GO:0070925 110 0.097
meiotic nuclear division GO:0007126 4 0.097
developmental process involved in reproduction GO:0003006 27 0.094
ribosome assembly GO:0042255 1 0.089
single fertilization GO:0007338 3 0.087
muscle structure development GO:0061061 196 0.086
signal transduction GO:0007165 455 0.086
organic substance biosynthetic process GO:1901576 289 0.080
Human Mouse
single organism organelle organization GO:1902589 199 0.078
regulation of cellular biosynthetic process GO:0031326 245 0.078
Mouse
regulation of signaling GO:0023051 235 0.076
heterocycle metabolic process GO:0046483 290 0.075
gene expression GO:0010467 252 0.073
Human Mouse
phagocytosis GO:0006909 3 0.073
oxoacid metabolic process GO:0043436 31 0.073
cellular amino acid metabolic process GO:0006520 7 0.072
muscle cell differentiation GO:0042692 139 0.068
regulation of multicellular organism growth GO:0040014 4 0.067
tube morphogenesis GO:0035239 349 0.067
lipid storage GO:0019915 1 0.067
reproduction GO:0000003 40 0.063
hydrogen peroxide metabolic process GO:0042743 2 0.061
positive regulation of cellular process GO:0048522 201 0.060
multicellular organism growth GO:0035264 4 0.058
single organism localization GO:1902578 225 0.057
cellular macromolecule metabolic process GO:0044260 391 0.055
Human Mouse
nucleobase containing compound metabolic process GO:0006139 274 0.053
cellular component morphogenesis GO:0032989 336 0.048
sexual reproduction GO:0019953 36 0.048
germ cell development GO:0007281 22 0.048
regulation of metabolic process GO:0019222 359 0.046
Mouse
muscle organ development GO:0007517 101 0.045
regulation of macromolecule metabolic process GO:0060255 317 0.045
Mouse
positive regulation of macromolecule metabolic process GO:0010604 93 0.045
carboxylic acid metabolic process GO:0019752 22 0.044
multicellular organismal reproductive process GO:0048609 35 0.043
multicellular organism reproduction GO:0032504 35 0.042
ribosome biogenesis GO:0042254 9 0.040
positive regulation of neural precursor cell proliferation GO:2000179 1 0.039
developmental growth GO:0048589 166 0.039
organic acid metabolic process GO:0006082 31 0.037
protein metabolic process GO:0019538 183 0.037
Human Mouse
regulation of gene expression GO:0010468 265 0.036
Mouse
reproductive process GO:0022414 40 0.035
guanosine containing compound metabolic process GO:1901068 4 0.035
organonitrogen compound metabolic process GO:1901564 74 0.034
spermatid development GO:0007286 2 0.034
establishment of protein localization to organelle GO:0072594 4 0.034
gtp metabolic process GO:0046039 4 0.033
organic cyclic compound biosynthetic process GO:1901362 223 0.033
maturation of ssu rrna from tricistronic rrna transcript ssu rrna 5 8s rrna lsu rrna GO:0000462 1 0.033
oocyte anterior posterior axis specification GO:0007314 4 0.033
response to stress GO:0006950 263 0.033
Mouse
transport GO:0006810 220 0.032
spermatid differentiation GO:0048515 2 0.032
regulation of skeletal muscle tissue development GO:0048641 4 0.032
negative regulation of macromolecule biosynthetic process GO:0010558 48 0.032
regulation of purine nucleotide catabolic process GO:0033121 2 0.031
embryonic organ development GO:0048568 381 0.031
brain development GO:0007420 293 0.030
positive regulation of multicellular organismal process GO:0051240 52 0.030
oogenesis GO:0048477 14 0.030
striated muscle cell differentiation GO:0051146 129 0.029
regulation of nucleoside metabolic process GO:0009118 2 0.029
alpha amino acid metabolic process GO:1901605 3 0.028
positive regulation of stem cell proliferation GO:2000648 1 0.028
determination of bilateral symmetry GO:0009855 204 0.028
regulation of transcription dna templated GO:0006355 213 0.028
striated muscle tissue development GO:0014706 110 0.027
rna metabolic process GO:0016070 219 0.027
maintenance of location GO:0051235 4 0.026
regulation of cellular metabolic process GO:0031323 320 0.026
Mouse
cellular aromatic compound metabolic process GO:0006725 295 0.026
cell surface receptor signaling pathway GO:0007166 325 0.026
positive regulation of metabolic process GO:0009893 108 0.025
glucose homeostasis GO:0042593 1 0.025
cellular protein metabolic process GO:0044267 129 0.025
Human Mouse
female gamete generation GO:0007292 14 0.025
single organism reproductive process GO:0044702 40 0.025
establishment of localization GO:0051234 244 0.025
organelle fission GO:0048285 23 0.024
negative regulation of biological process GO:0048519 304 0.024
response to wounding GO:0009611 116 0.024
small molecule metabolic process GO:0044281 77 0.024
heart development GO:0007507 313 0.023
fertilization GO:0009566 3 0.023
positive regulation of muscle tissue development GO:1901863 1 0.023
skeletal muscle tissue development GO:0007519 67 0.023
cellular component assembly involved in morphogenesis GO:0010927 107 0.023
negative regulation of cellular process GO:0048523 283 0.022
skeletal muscle organ development GO:0060538 78 0.022
macromolecular complex subunit organization GO:0043933 74 0.021
leukocyte proliferation GO:0070661 1 0.021
regulation of anatomical structure morphogenesis GO:0022603 130 0.020
skeletal system development GO:0001501 181 0.020
regulation of myotube differentiation GO:0010830 2 0.020
regulation of biosynthetic process GO:0009889 250 0.019
Mouse
regulation of gtp catabolic process GO:0033124 2 0.019
regulation of cell differentiation GO:0045595 142 0.019
regulation of apoptotic process GO:0042981 98 0.019
embryonic viscerocranium morphogenesis GO:0048703 52 0.019
carbohydrate homeostasis GO:0033500 1 0.019
protein secretion GO:0009306 1 0.018
cellular component movement GO:0006928 335 0.018
regulation of rna metabolic process GO:0051252 224 0.018
determination of left right symmetry GO:0007368 179 0.018
single organism metabolic process GO:0044710 217 0.018
cellular nitrogen compound biosynthetic process GO:0044271 218 0.018
muscle cell migration GO:0014812 4 0.018
maturation of ssu rrna GO:0030490 1 0.018
cell cell recognition GO:0009988 1 0.017
post embryonic development GO:0009791 7 0.017
Worm
digestive tract development GO:0048565 265 0.017
positive regulation of striated muscle tissue development GO:0045844 1 0.017
single organism biosynthetic process GO:0044711 71 0.017
regulation of i kappab kinase nf kappab signaling GO:0043122 4 0.017
protein modification process GO:0036211 100 0.017
Mouse
skeletal muscle fiber development GO:0048741 35 0.017
digestive tract morphogenesis GO:0048546 231 0.017
regulation of signal transduction GO:0009966 225 0.017
regulation of nucleotide catabolic process GO:0030811 2 0.016
regulation of gtpase activity GO:0043087 2 0.016
growth GO:0040007 174 0.016
Worm
adult behavior GO:0030534 2 0.016
regulation of macromolecule biosynthetic process GO:0010556 225 0.015
Mouse
rna processing GO:0006396 25 0.015
translation GO:0006412 5 0.015
Human Mouse
positive regulation of i kappab kinase nf kappab signaling GO:0043123 3 0.015
nucleic acid templated transcription GO:0097659 181 0.015
cell migration GO:0016477 237 0.015
lymphocyte proliferation GO:0046651 1 0.015
sensory organ development GO:0007423 393 0.015
cell death GO:0008219 121 0.014
specification of symmetry GO:0009799 204 0.014
immune effector process GO:0002252 23 0.014
cell motility GO:0048870 244 0.014
positive regulation of cellular metabolic process GO:0031325 94 0.014
neuron development GO:0048666 262 0.014
muscle cell development GO:0055001 115 0.014
negative regulation of rna biosynthetic process GO:1902679 45 0.014
positive regulation of purine nucleotide catabolic process GO:0033123 1 0.014
cellular amine metabolic process GO:0044106 2 0.014
g1 s transition of mitotic cell cycle GO:0000082 1 0.014
cognition GO:0050890 1 0.014
regulation of developmental process GO:0050793 247 0.014
negative regulation of gene expression GO:0010629 65 0.014
cellular protein modification process GO:0006464 100 0.014
Mouse
generation of neurons GO:0048699 385 0.013
regulation of rna biosynthetic process GO:2001141 213 0.013
hemopoiesis GO:0030097 183 0.013
negative regulation of cellular biosynthetic process GO:0031327 55 0.013
phagocytosis engulfment GO:0006911 1 0.013
positive regulation of nucleoside metabolic process GO:0045979 1 0.013
heterocycle biosynthetic process GO:0018130 215 0.013
response to chemical GO:0042221 320 0.013
actin filament based movement GO:0030048 1 0.013
i kappab kinase nf kappab signaling GO:0007249 4 0.013
protein complex subunit organization GO:0071822 46 0.013
eye development GO:0001654 277 0.013
regulation of fatty acid metabolic process GO:0019217 1 0.013
regulation of nitrogen compound metabolic process GO:0051171 251 0.013
regulation of skeletal muscle fiber development GO:0048742 2 0.013
cellular ketone metabolic process GO:0042180 11 0.013
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.013
Mouse
negative regulation of cell cycle process GO:0010948 9 0.012
pancreas development GO:0031016 84 0.012
morphogenesis of an epithelium GO:0002009 333 0.012
mitotic dna damage checkpoint GO:0044773 4 0.012
nuclear transport GO:0051169 4 0.012
embryonic heart tube development GO:0035050 133 0.012
negative regulation of nitrogen compound metabolic process GO:0051172 59 0.012
neurological system process GO:0050877 62 0.012
negative regulation of metabolic process GO:0009892 86 0.012
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.012
positive regulation of gtp catabolic process GO:0033126 1 0.012
cell projection organization GO:0030030 284 0.012
regulation of cellular amine metabolic process GO:0033238 0 0.012
cytoskeleton organization GO:0007010 96 0.012
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.012
striated muscle cell development GO:0055002 108 0.011
amine metabolic process GO:0009308 2 0.011
muscle tissue development GO:0060537 110 0.011
microtubule organizing center organization GO:0031023 1 0.011
guanosine containing compound catabolic process GO:1901069 2 0.011
embryonic cranial skeleton morphogenesis GO:0048701 90 0.011
gastrulation GO:0007369 208 0.011
membrane organization GO:0061024 21 0.011
myotube cell development GO:0014904 35 0.011
positive regulation of biosynthetic process GO:0009891 68 0.011
behavior GO:0007610 74 0.011
transcription from rna polymerase iii promoter GO:0006383 1 0.011
neuron differentiation GO:0030182 353 0.011
positive regulation of gtpase activity GO:0043547 1 0.011
mitotic dna integrity checkpoint GO:0044774 4 0.011
cell substrate junction assembly GO:0007044 2 0.011
wound healing GO:0042060 90 0.011
nucleobase containing compound biosynthetic process GO:0034654 205 0.011
sympathetic ganglion development GO:0061549 2 0.011
spindle assembly involved in mitosis GO:0090307 1 0.010
regulation of inner ear receptor cell differentiation GO:2000980 1 0.010
regulation of mechanoreceptor differentiation GO:0045631 1 0.010
regulation of response to stimulus GO:0048583 269 0.010
protein stabilization GO:0050821 2 0.010
cell cycle g1 s phase transition GO:0044843 1 0.010
positive regulation of dna templated transcription elongation GO:0032786 1 0.010

eif2s1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.303
hematopoietic system disease DOID:74 0 0.218
immune system disease DOID:2914 0 0.218
bone marrow disease DOID:4961 0 0.218
anemia DOID:2355 0 0.065
neuromuscular disease DOID:440 0 0.040
nervous system disease DOID:863 0 0.040
neuropathy DOID:870 0 0.040
charcot marie tooth disease DOID:10595 0 0.040
diamond blackfan anemia DOID:1339 0 0.037
aplastic anemia DOID:12449 0 0.037
congenital hypoplastic anemia DOID:1342 0 0.037
cardiovascular system disease DOID:1287 0 0.035