Danio rerio

32 known processes

eif3b

eukaryotic translation initiation factor 3, subunit B

(Aliases: eif3s9,wu:fc17c01)

eif3b biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
single fertilization GO:0007338 3 0.762
regulation of gene expression GO:0010468 265 0.655
Human
macromolecule biosynthetic process GO:0009059 227 0.538
Human Yeast Mouse
locomotion GO:0040011 313 0.525
Worm
translational initiation GO:0006413 3 0.515
Human Yeast Mouse
larval development GO:0002164 2 0.512
Worm
embryo development ending in birth or egg hatching GO:0009792 271 0.489
Worm
cellular biosynthetic process GO:0044249 286 0.474
Human Yeast Mouse
cellular macromolecule biosynthetic process GO:0034645 224 0.454
Human Yeast Mouse
establishment of localization GO:0051234 244 0.402
Worm
embryonic organ development GO:0048568 381 0.373
regulation of macromolecule metabolic process GO:0060255 317 0.339
Human
organic cyclic compound metabolic process GO:1901360 301 0.332
negative regulation of cellular process GO:0048523 283 0.285
biosynthetic process GO:0009058 294 0.276
Human Yeast Mouse
organic substance biosynthetic process GO:1901576 289 0.229
Human Yeast Mouse
gene expression GO:0010467 252 0.228
Human Yeast Mouse
transport GO:0006810 220 0.225
Worm
fertilization GO:0009566 3 0.178
small molecule metabolic process GO:0044281 77 0.168
cellular aromatic compound metabolic process GO:0006725 295 0.158
carbohydrate derivative metabolic process GO:1901135 61 0.152
embryonic organ morphogenesis GO:0048562 274 0.151
single organism transport GO:0044765 206 0.149
nucleic acid metabolic process GO:0090304 244 0.149
heterocycle biosynthetic process GO:0018130 215 0.145
rna modification GO:0009451 2 0.144
regulation of primary metabolic process GO:0080090 311 0.141
Human
cellular nitrogen compound metabolic process GO:0034641 290 0.141
regulation of biosynthetic process GO:0009889 250 0.137
Human
spindle assembly involved in mitosis GO:0090307 1 0.136
organonitrogen compound metabolic process GO:1901564 74 0.126
toxin transport GO:1901998 2 0.123
death GO:0016265 121 0.121
Worm
translation GO:0006412 5 0.120
Human Yeast Mouse
cell death GO:0008219 121 0.114
Worm
tube morphogenesis GO:0035239 349 0.114
nucleic acid templated transcription GO:0097659 181 0.110
protein metabolic process GO:0019538 183 0.110
Human Yeast Mouse
positive regulation of biological process GO:0048518 253 0.109
sexual reproduction GO:0019953 36 0.107
gamete generation GO:0007276 33 0.106
cellular macromolecule metabolic process GO:0044260 391 0.104
Human Yeast Mouse
negative regulation of macromolecule metabolic process GO:0010605 76 0.096
oocyte anterior posterior axis specification GO:0007314 4 0.092
regulation of response to stimulus GO:0048583 269 0.088
microtubule cytoskeleton organization involved in mitosis GO:1902850 1 0.087
negative regulation of biological process GO:0048519 304 0.086
multicellular organism growth GO:0035264 4 0.086
hematopoietic or lymphoid organ development GO:0048534 191 0.082
regulation of anatomical structure morphogenesis GO:0022603 130 0.077
microtubule organizing center organization GO:0031023 1 0.076
regulation of metabolic process GO:0019222 359 0.076
Human
cell projection morphogenesis GO:0048858 244 0.075
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.075
Human
neuron projection development GO:0031175 180 0.074
cell surface receptor signaling pathway GO:0007166 325 0.072
germ cell development GO:0007281 22 0.072
maturation of ssu rrna from tricistronic rrna transcript ssu rrna 5 8s rrna lsu rrna GO:0000462 1 0.072
positive regulation of translation GO:0045727 1 0.072
cell morphogenesis GO:0000902 289 0.070
neuron development GO:0048666 262 0.069
regulation of signal transduction GO:0009966 225 0.068
multicellular organismal reproductive process GO:0048609 35 0.066
regulation of protein metabolic process GO:0051246 56 0.064
Human
cell motility GO:0048870 244 0.064
regulation of apoptotic process GO:0042981 98 0.064
spermatid development GO:0007286 2 0.064
aging GO:0007568 2 0.063
Worm
skeletal system morphogenesis GO:0048705 102 0.063
cellular amino acid metabolic process GO:0006520 7 0.062
organic cyclic compound biosynthetic process GO:1901362 223 0.062
generation of neurons GO:0048699 385 0.062
single organism organelle organization GO:1902589 199 0.061
head development GO:0060322 303 0.061
nucleoside monophosphate catabolic process GO:0009125 4 0.061
negative regulation of metabolic process GO:0009892 86 0.059
er nucleus signaling pathway GO:0006984 2 0.059
heterocycle metabolic process GO:0046483 290 0.058
regulation of multicellular organism growth GO:0040014 4 0.058
cellular component movement GO:0006928 335 0.058
spindle assembly GO:0051225 2 0.057
regionalization GO:0003002 274 0.056
programmed cell death GO:0012501 119 0.056
Worm
mitotic dna integrity checkpoint GO:0044774 4 0.055
negative regulation of cellular metabolic process GO:0031324 77 0.055
rna metabolic process GO:0016070 219 0.054
microtubule based process GO:0007017 60 0.053
cell migration GO:0016477 237 0.053
neuron differentiation GO:0030182 353 0.052
phosphate containing compound metabolic process GO:0006796 108 0.052
regulation of signaling GO:0023051 235 0.052
apoptotic process GO:0006915 116 0.051
Worm
meiotic nuclear division GO:0007126 4 0.050
embryonic cranial skeleton morphogenesis GO:0048701 90 0.050
aromatic compound biosynthetic process GO:0019438 217 0.049
cellular protein metabolic process GO:0044267 129 0.048
Human Yeast Mouse
multicellular organism reproduction GO:0032504 35 0.048
cellular process involved in reproduction in multicellular organism GO:0022412 28 0.047
pigmentation GO:0043473 85 0.046
nucleobase containing compound metabolic process GO:0006139 274 0.045
organelle assembly GO:0070925 110 0.045
regulation of cellular metabolic process GO:0031323 320 0.045
Human
embryonic skeletal system development GO:0048706 97 0.044
meiotic cell cycle process GO:1903046 3 0.044
skeletal system development GO:0001501 181 0.043
gtp metabolic process GO:0046039 4 0.043
regulation of cell death GO:0010941 103 0.043
signal transduction GO:0007165 455 0.042
response to amino acid GO:0043200 2 0.042
central nervous system development GO:0007417 387 0.042
posttranscriptional regulation of gene expression GO:0010608 14 0.041
Human
spermatid differentiation GO:0048515 2 0.040
response to chemical GO:0042221 320 0.040
ribonucleoside monophosphate catabolic process GO:0009158 4 0.040
reproductive process GO:0022414 40 0.039
regulation of translation GO:0006417 3 0.039
Human
regulation of protein transport GO:0051223 3 0.038
fin regeneration GO:0031101 51 0.037
cell cycle GO:0007049 93 0.037
organic acid metabolic process GO:0006082 31 0.037
phagocytosis GO:0006909 3 0.036
regulation of translational initiation GO:0006446 1 0.036
Human
single organism localization GO:1902578 225 0.035
oogenesis GO:0048477 14 0.035
guanosine containing compound catabolic process GO:1901069 2 0.035
positive regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043280 10 0.035
regulation of cell communication GO:0010646 232 0.034
nucleobase containing small molecule metabolic process GO:0055086 32 0.034
multi organism process GO:0051704 134 0.034
organelle organization GO:0006996 227 0.034
gtp catabolic process GO:0006184 2 0.034
negative regulation of protein phosphorylation GO:0001933 4 0.034
response to stress GO:0006950 263 0.034
negative regulation of biosynthetic process GO:0009890 55 0.033
intracellular signal transduction GO:0035556 85 0.033
microtubule cytoskeleton organization GO:0000226 33 0.033
guanosine containing compound metabolic process GO:1901068 4 0.033
positive regulation of apoptotic signaling pathway GO:2001235 1 0.033
regulation of establishment of protein localization GO:0070201 4 0.032
digestive tract morphogenesis GO:0048546 231 0.032
carboxylic acid metabolic process GO:0019752 22 0.032
vasculature development GO:0001944 278 0.032
regulation of programmed cell death GO:0043067 101 0.031
neuron projection morphogenesis GO:0048812 161 0.031
cellular nitrogen compound biosynthetic process GO:0044271 218 0.031
regulation of macromolecule biosynthetic process GO:0010556 225 0.031
Human
mitotic cell cycle GO:0000278 64 0.031
establishment of protein localization to plasma membrane GO:0090002 1 0.031
purine ribonucleoside monophosphate catabolic process GO:0009169 4 0.031
negative regulation of cellular biosynthetic process GO:0031327 55 0.031
multi organism reproductive process GO:0044703 36 0.031
negative regulation of apoptotic process GO:0043066 55 0.031
maintenance of location GO:0051235 4 0.030
Worm
pole plasm assembly GO:0007315 4 0.030
embryonic skeletal system morphogenesis GO:0048704 93 0.029
regulation of cellular biosynthetic process GO:0031326 245 0.029
Human
cell projection organization GO:0030030 284 0.029
sensory organ development GO:0007423 393 0.028
cellular localization GO:0051641 97 0.028
regulation of developmental process GO:0050793 247 0.028
nuclear transport GO:0051169 4 0.028
positive regulation of macromolecule metabolic process GO:0010604 93 0.028
rna biosynthetic process GO:0032774 181 0.027
vesicle mediated transport GO:0016192 22 0.027
Worm
regulation of protein catabolic process GO:0042176 1 0.027
regulation of nucleotide catabolic process GO:0030811 2 0.027
establishment of localization in cell GO:0051649 77 0.027
regulation of cellular protein catabolic process GO:1903362 1 0.026
cellular component morphogenesis GO:0032989 336 0.026
positive regulation of catabolic process GO:0009896 4 0.026
transcription dna templated GO:0006351 181 0.026
cell cell recognition GO:0009988 1 0.025
brain development GO:0007420 293 0.025
immune system development GO:0002520 191 0.025
developmental growth GO:0048589 166 0.025
positive regulation of metabolic process GO:0009893 108 0.024
cellular component disassembly GO:0022411 1 0.024
reproduction GO:0000003 40 0.024
Worm
regulation of biological quality GO:0065008 263 0.024
Worm
digestive system development GO:0055123 289 0.024
nucleocytoplasmic transport GO:0006913 4 0.023
cell cycle g1 s phase transition GO:0044843 1 0.023
chordate embryonic development GO:0043009 271 0.023
oxoacid metabolic process GO:0043436 31 0.023
negative regulation of signal transduction GO:0009968 94 0.023
female gamete generation GO:0007292 14 0.023
organic cyclic compound catabolic process GO:1901361 15 0.023
carbohydrate homeostasis GO:0033500 1 0.023
nitrogen compound metabolic process GO:0006807 319 0.023
regulation of molecular function GO:0065009 70 0.022
cellular amine metabolic process GO:0044106 2 0.022
purine nucleoside monophosphate catabolic process GO:0009128 4 0.022
cytokinesis GO:0000910 3 0.022
modification dependent protein catabolic process GO:0019941 3 0.022
lipid storage GO:0019915 1 0.021
Worm
negative regulation of response to stimulus GO:0048585 104 0.021
embryonic viscerocranium morphogenesis GO:0048703 52 0.021
single organism metabolic process GO:0044710 217 0.021
positive regulation of cellular catabolic process GO:0031331 3 0.021
regulation of cellular amine metabolic process GO:0033238 0 0.021
nuclear import GO:0051170 3 0.021
regulation of neuron apoptotic process GO:0043523 17 0.020
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 1 0.020
single organism reproductive process GO:0044702 40 0.020
cellular response to chemical stimulus GO:0070887 157 0.020
regulation of transcription from rna polymerase ii promoter GO:0006357 114 0.020
blood vessel morphogenesis GO:0048514 216 0.020
atp catabolic process GO:0006200 4 0.020
maturation of ssu rrna GO:0030490 1 0.020
establishment of protein localization to organelle GO:0072594 4 0.020
neuromuscular process controlling balance GO:0050885 3 0.020
system process GO:0003008 185 0.020
nucleoside metabolic process GO:0009116 11 0.020
cellular response to external stimulus GO:0071496 2 0.019
embryonic digestive tract morphogenesis GO:0048557 3 0.019
amine metabolic process GO:0009308 2 0.019
regulation of binding GO:0051098 3 0.019
regulation of erk1 and erk2 cascade GO:0070372 4 0.019
regulation of cytoplasmic transport GO:1903649 4 0.019
maternal determination of anterior posterior axis embryo GO:0008358 4 0.018
nucleotide metabolic process GO:0009117 28 0.018
negative regulation of nucleobase containing compound metabolic process GO:0045934 59 0.018
regulation of carbohydrate metabolic process GO:0006109 4 0.018
pore complex assembly GO:0046931 2 0.018
cell part morphogenesis GO:0032990 246 0.018
phosphorus metabolic process GO:0006793 109 0.018
ribosome assembly GO:0042255 1 0.018
response to glucose GO:0009749 3 0.018
endoplasmic reticulum unfolded protein response GO:0030968 2 0.018
regulation of nitrogen compound metabolic process GO:0051171 251 0.018
mitotic spindle organization GO:0007052 5 0.018
negative regulation of translation GO:0017148 1 0.017
regulation of cellular response to oxidative stress GO:1900407 2 0.017
i kappab kinase nf kappab signaling GO:0007249 4 0.017
nucleic acid transport GO:0050657 2 0.017
regulation of purine nucleotide catabolic process GO:0033121 2 0.017
aromatic compound catabolic process GO:0019439 15 0.017
negative regulation of cell death GO:0060548 60 0.017
centrosome organization GO:0051297 1 0.017
response to carbohydrate GO:0009743 3 0.017
developmental process involved in reproduction GO:0003006 27 0.017
cell cycle process GO:0022402 53 0.017
cytoskeleton organization GO:0007010 96 0.017
camera type eye development GO:0043010 222 0.017
regulation of i kappab kinase nf kappab signaling GO:0043122 4 0.016
neuron apoptotic process GO:0051402 20 0.016
cellular macromolecule localization GO:0070727 21 0.016
negative regulation of cell differentiation GO:0045596 46 0.016
negative regulation of cell communication GO:0010648 96 0.016
negative regulation of dna metabolic process GO:0051053 4 0.016
cellular component biogenesis GO:0044085 178 0.016
g1 s transition of mitotic cell cycle GO:0000082 1 0.016
rna localization GO:0006403 4 0.015
negative regulation of programmed cell death GO:0043069 58 0.015
regulation of nucleic acid templated transcription GO:1903506 213 0.015
organophosphate metabolic process GO:0019637 37 0.015
protein complex subunit organization GO:0071822 46 0.015
protein secretion GO:0009306 1 0.015
regulation of transcription dna templated GO:0006355 213 0.015
regulation of protein targeting GO:1903533 2 0.015
immune system process GO:0002376 241 0.015
pronuclear migration GO:0035046 1 0.015
cell death in response to oxidative stress GO:0036473 2 0.015
regulation of response to oxidative stress GO:1902882 2 0.015
circadian sleep wake cycle sleep GO:0050802 1 0.015
negative regulation of protein kinase activity GO:0006469 4 0.015
regeneration GO:0031099 91 0.014
regulation of wnt signaling pathway GO:0030111 53 0.014
regulation of cellular protein metabolic process GO:0032268 52 0.014
Human
nucleoside phosphate metabolic process GO:0006753 28 0.014
negative regulation of wnt signaling pathway GO:0030178 30 0.014
purine nucleotide metabolic process GO:0006163 27 0.014
meiotic chromosome segregation GO:0045132 3 0.014
hemopoiesis GO:0030097 183 0.014
digestive tract development GO:0048565 265 0.014
cell type specific apoptotic process GO:0097285 22 0.014
negative regulation of kinase activity GO:0033673 4 0.014
cellular nitrogen compound catabolic process GO:0044270 15 0.014
skin development GO:0043588 54 0.014
neurological system process GO:0050877 62 0.014
cell proliferation involved in heart morphogenesis GO:0061323 2 0.014
cellular catabolic process GO:0044248 27 0.013
catabolic process GO:0009056 32 0.013
regulation of gtpase activity GO:0043087 2 0.013
regulation of cellular amino acid metabolic process GO:0006521 0 0.013
heterocycle catabolic process GO:0046700 15 0.013
rna 3 end processing GO:0031123 2 0.013
purine ribonucleotide metabolic process GO:0009150 27 0.013
negative regulation of cell cycle GO:0045786 14 0.013
kupffer s vesicle development GO:0070121 50 0.013
positive regulation of apoptotic process GO:0043065 29 0.013
glucose homeostasis GO:0042593 1 0.013
pigment granule localization GO:0051875 25 0.012
response to organic substance GO:0010033 153 0.012
g2 dna damage checkpoint GO:0031572 3 0.012
regulation of oxidative stress induced cell death GO:1903201 2 0.012
lymphocyte proliferation GO:0046651 1 0.012
protein stabilization GO:0050821 2 0.012
nucleobase containing compound biosynthetic process GO:0034654 205 0.012
gastrulation GO:0007369 208 0.012
positive regulation of cellular process GO:0048522 201 0.012
regulation of gtp catabolic process GO:0033124 2 0.012
cellular response to extracellular stimulus GO:0031668 2 0.012
growth GO:0040007 174 0.012
cellular carbohydrate metabolic process GO:0044262 4 0.012
negative regulation of gene expression GO:0010629 65 0.012
receptor mediated endocytosis GO:0006898 6 0.011
Worm
negative regulation of signaling GO:0023057 96 0.011
regulation of multicellular organismal process GO:0051239 277 0.011
developmental programmed cell death GO:0010623 4 0.011
negative regulation of cellular macromolecule biosynthetic process GO:2000113 48 0.011
positive regulation of gene expression GO:0010628 71 0.011
response to unfolded protein GO:0006986 2 0.011
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 4 0.011
tissue regeneration GO:0042246 74 0.011
regulation of rna metabolic process GO:0051252 224 0.011
nuclear migration GO:0007097 3 0.011
positive regulation of cellular biosynthetic process GO:0031328 68 0.011
response to wounding GO:0009611 116 0.011
mononuclear cell proliferation GO:0032943 1 0.011
cellular protein complex disassembly GO:0043624 1 0.011
positive regulation of i kappab kinase nf kappab signaling GO:0043123 3 0.011
response to oxygen containing compound GO:1901700 55 0.011
regulation of transcription elongation from rna polymerase ii promoter GO:0034243 3 0.011
negative regulation of developmental process GO:0051093 65 0.011
regulation of protein localization to plasma membrane GO:1903076 1 0.010
positive regulation of camp metabolic process GO:0030816 2 0.010
protein localization to plasma membrane GO:0072659 1 0.010
cellular response to stress GO:0033554 62 0.010
organelle localization GO:0051640 49 0.010
hindbrain development GO:0030902 91 0.010
ribonucleotide metabolic process GO:0009259 27 0.010
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 20 0.010
regulation of mitotic cell cycle GO:0007346 25 0.010
ribose phosphate metabolic process GO:0019693 27 0.010
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.010
cellular response to xenobiotic stimulus GO:0071466 35 0.010
positive regulation of cellular metabolic process GO:0031325 94 0.010
regulation of multicellular organismal development GO:2000026 223 0.010
morphogenesis of an epithelium GO:0002009 333 0.010
negative regulation of nuclear division GO:0051784 3 0.010
neuron death GO:0070997 21 0.010
response to hydrogen peroxide GO:0042542 3 0.010

eif3b disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.114
neuromuscular disease DOID:440 0 0.031
charcot marie tooth disease type 2 DOID:0050539 0 0.031
charcot marie tooth disease DOID:10595 0 0.031
nervous system disease DOID:863 0 0.031
neuropathy DOID:870 0 0.031