Danio rerio

0 known processes

eif4e3

eukaryotic translation initiation factor 4E family member 3

(Aliases: wu:fd15f11,wu:fc31f11,zgc:92189)

eif4e3 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
single organism metabolic process GO:0044710 217 0.127
positive regulation of transport GO:0051050 2 0.122
cellular macromolecule metabolic process GO:0044260 391 0.119
nitrogen compound metabolic process GO:0006807 319 0.105
organic cyclic compound metabolic process GO:1901360 301 0.101
aging GO:0007568 2 0.095
cellular aromatic compound metabolic process GO:0006725 295 0.088
larval development GO:0002164 2 0.087
cellular nitrogen compound metabolic process GO:0034641 290 0.083
regulation of biosynthetic process GO:0009889 250 0.076
positive regulation of biological process GO:0048518 253 0.073
organic cyclic compound biosynthetic process GO:1901362 223 0.069
response to uv GO:0009411 3 0.065
organic substance biosynthetic process GO:1901576 289 0.062
regulation of nucleic acid templated transcription GO:1903506 213 0.061
cellular nitrogen compound biosynthetic process GO:0044271 218 0.058
secondary metabolic process GO:0019748 3 0.057
heterocycle metabolic process GO:0046483 290 0.057
regulation of nitrogen compound metabolic process GO:0051171 251 0.057
organelle organization GO:0006996 227 0.057
rna metabolic process GO:0016070 219 0.056
cellular biosynthetic process GO:0044249 286 0.056
negative regulation of cellular process GO:0048523 283 0.056
regulation of gene expression GO:0010468 265 0.055
regulation of primary metabolic process GO:0080090 311 0.054
regulation of biological quality GO:0065008 263 0.054
establishment of protein localization to organelle GO:0072594 4 0.053
nucleic acid metabolic process GO:0090304 244 0.052
heterocycle biosynthetic process GO:0018130 215 0.050
single organism biosynthetic process GO:0044711 71 0.048
positive regulation of cellular process GO:0048522 201 0.046
aromatic compound biosynthetic process GO:0019438 217 0.046
ribonucleoside monophosphate catabolic process GO:0009158 4 0.046
biosynthetic process GO:0009058 294 0.046
cellular ketone metabolic process GO:0042180 11 0.044
leukocyte proliferation GO:0070661 1 0.043
nucleobase containing compound metabolic process GO:0006139 274 0.043
macromolecule biosynthetic process GO:0009059 227 0.043
rna biosynthetic process GO:0032774 181 0.041
regulation of cell communication GO:0010646 232 0.039
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.039
erk1 and erk2 cascade GO:0070371 4 0.038
cell projection organization GO:0030030 284 0.038
phosphate containing compound metabolic process GO:0006796 108 0.038
cytoskeleton dependent cytokinesis GO:0061640 3 0.038
mitochondrion organization GO:0007005 4 0.038
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.037
nucleobase containing compound biosynthetic process GO:0034654 205 0.037
negative regulation of biological process GO:0048519 304 0.037
lipid catabolic process GO:0016042 4 0.036
protein localization to nucleus GO:0034504 3 0.036
protein metabolic process GO:0019538 183 0.036
cell migration GO:0016477 237 0.035
transcription dna templated GO:0006351 181 0.034
transport GO:0006810 220 0.034
morphogenesis of an epithelium GO:0002009 333 0.034
gene expression GO:0010467 252 0.034
glial cell migration GO:0008347 3 0.033
regulation of macromolecule metabolic process GO:0060255 317 0.033
immune system process GO:0002376 241 0.033
positive regulation of cellular component biogenesis GO:0044089 3 0.033
regulation of rna metabolic process GO:0051252 224 0.032
modification dependent protein catabolic process GO:0019941 3 0.032
proteasomal protein catabolic process GO:0010498 2 0.032
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.032
protein polyubiquitination GO:0000209 4 0.032
regulation of metabolic process GO:0019222 359 0.031
nucleoside monophosphate catabolic process GO:0009125 4 0.031
regulation of cell shape GO:0008360 1 0.031
positive regulation of catabolic process GO:0009896 4 0.031
mononuclear cell proliferation GO:0032943 1 0.031
guanosine containing compound metabolic process GO:1901068 4 0.031
nucleic acid templated transcription GO:0097659 181 0.031
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 2 0.030
cellular response to external stimulus GO:0071496 2 0.029
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.029
regulation of establishment of protein localization GO:0070201 4 0.029
regulation of cellular metabolic process GO:0031323 320 0.029
organelle fusion GO:0048284 3 0.028
autophagy GO:0006914 4 0.028
small molecule metabolic process GO:0044281 77 0.028
regulation of protein catabolic process GO:0042176 1 0.028
intracellular signal transduction GO:0035556 85 0.028
regulation of blood pressure GO:0008217 1 0.028
modification dependent macromolecule catabolic process GO:0043632 3 0.028
regulation of tube size GO:0035150 2 0.027
atp catabolic process GO:0006200 4 0.027
determination of bilateral symmetry GO:0009855 204 0.027
protein dephosphorylation GO:0006470 3 0.027
response to external stimulus GO:0009605 264 0.027
cell morphogenesis involved in differentiation GO:0000904 195 0.027
cellular protein catabolic process GO:0044257 4 0.026
odontogenesis of dentin containing tooth GO:0042475 1 0.026
single organism nuclear import GO:1902593 3 0.026
single organism localization GO:1902578 225 0.026
cell motility GO:0048870 244 0.026
cellular response to extracellular stimulus GO:0031668 2 0.026
positive regulation of secretion GO:0051047 1 0.025
regulation of cellular biosynthetic process GO:0031326 245 0.025
cell morphogenesis GO:0000902 289 0.025
localization of cell GO:0051674 244 0.025
cellular protein metabolic process GO:0044267 129 0.025
regulation of cell differentiation GO:0045595 142 0.025
regulation of synapse organization GO:0050807 3 0.025
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.025
heart development GO:0007507 313 0.025
regulation of erk1 and erk2 cascade GO:0070372 4 0.025
regulation of rna biosynthetic process GO:2001141 213 0.025
response to chemical GO:0042221 320 0.025
lipid homeostasis GO:0055088 3 0.024
gland development GO:0048732 143 0.024
determination of left right symmetry GO:0007368 179 0.024
protein localization to plasma membrane GO:0072659 1 0.023
brain development GO:0007420 293 0.023
extrinsic apoptotic signaling pathway GO:0097191 3 0.023
phosphorus metabolic process GO:0006793 109 0.023
phagocytosis GO:0006909 3 0.023
regulation of i kappab kinase nf kappab signaling GO:0043122 4 0.023
axonogenesis GO:0007409 152 0.022
cellular component movement GO:0006928 335 0.022
cell part morphogenesis GO:0032990 246 0.022
specification of symmetry GO:0009799 204 0.022
establishment of protein localization to plasma membrane GO:0090002 1 0.022
internal protein amino acid acetylation GO:0006475 2 0.022
single organism organelle organization GO:1902589 199 0.022
negative regulation of protein kinase activity GO:0006469 4 0.022
multicellular organism growth GO:0035264 4 0.022
phosphorylation GO:0016310 69 0.022
positive regulation of protein complex assembly GO:0031334 2 0.022
protein import into nucleus GO:0006606 3 0.022
stem cell proliferation GO:0072089 4 0.022
cellular macromolecule biosynthetic process GO:0034645 224 0.022
signal transduction GO:0007165 455 0.022
apoptotic process involved in development GO:1902742 2 0.022
positive regulation of stress activated protein kinase signaling cascade GO:0070304 3 0.021
regulation of cellular ketone metabolic process GO:0010565 7 0.021
regulation of axonogenesis GO:0050770 32 0.021
cell substrate adhesion GO:0031589 4 0.021
nuclear import GO:0051170 3 0.021
gtp catabolic process GO:0006184 2 0.021
macromolecule modification GO:0043412 111 0.021
neurotransmitter transport GO:0006836 2 0.021
negative regulation of protein phosphorylation GO:0001933 4 0.021
purine nucleoside monophosphate catabolic process GO:0009128 4 0.021
internal peptidyl lysine acetylation GO:0018393 2 0.021
regulation of epithelial cell proliferation GO:0050678 3 0.021
regulation of cell activation GO:0050865 1 0.021
ubiquitin dependent protein catabolic process GO:0006511 3 0.020
regulation of blood vessel size GO:0050880 2 0.020
regulation of transcription dna templated GO:0006355 213 0.020
positive regulation of map kinase activity GO:0043406 3 0.020
positive regulation of erk1 and erk2 cascade GO:0070374 2 0.020
locomotion GO:0040011 313 0.020
regulation of binding GO:0051098 3 0.020
regulation of developmental process GO:0050793 247 0.020
hepaticobiliary system development GO:0061008 98 0.019
purine ribonucleoside monophosphate catabolic process GO:0009169 4 0.019
negative regulation of kinase activity GO:0033673 4 0.019
developmental growth involved in morphogenesis GO:0060560 86 0.019
fatty acid catabolic process GO:0009062 1 0.019
signal transduction in absence of ligand GO:0038034 1 0.019
b cell activation GO:0042113 2 0.019
extrinsic apoptotic signaling pathway via death domain receptors GO:0008625 1 0.019
cellular carbohydrate metabolic process GO:0044262 4 0.019
axon development GO:0061564 166 0.019
meiotic nuclear division GO:0007126 4 0.019
establishment of localization GO:0051234 244 0.019
microtubule organizing center organization GO:0031023 1 0.019
oxoacid metabolic process GO:0043436 31 0.019
maintenance of location GO:0051235 4 0.019
regulation of nucleotide catabolic process GO:0030811 2 0.019
immune system development GO:0002520 191 0.019
regulation of multicellular organismal process GO:0051239 277 0.019
regulation of cyclin dependent protein serine threonine kinase activity GO:0000079 1 0.019
positive regulation of cell cycle GO:0045787 3 0.019
regulation of synapse assembly GO:0051963 3 0.019
regulation of neurogenesis GO:0050767 87 0.019
cellular response to nutrient levels GO:0031669 2 0.019
nucleocytoplasmic transport GO:0006913 4 0.019
cell aging GO:0007569 2 0.019
cellular catabolic process GO:0044248 27 0.018
cell surface receptor signaling pathway GO:0007166 325 0.018
regulation of systemic arterial blood pressure GO:0003073 1 0.018
positive regulation of metabolic process GO:0009893 108 0.018
peptidyl serine phosphorylation GO:0018105 1 0.018
g1 s transition of mitotic cell cycle GO:0000082 1 0.018
generation of neurons GO:0048699 385 0.018
transcription from rna polymerase ii promoter GO:0006366 80 0.018
urogenital system development GO:0001655 97 0.018
regulation of multicellular organism growth GO:0040014 4 0.017
i kappab kinase nf kappab signaling GO:0007249 4 0.017
central nervous system development GO:0007417 387 0.017
synaptic vesicle localization GO:0097479 1 0.017
mitochondrial transport GO:0006839 2 0.017
neuron differentiation GO:0030182 353 0.017
vasculature development GO:0001944 278 0.017
erythrocyte homeostasis GO:0034101 55 0.017
activation of mapk activity GO:0000187 3 0.017
apoptotic process GO:0006915 116 0.017
nuclear transport GO:0051169 4 0.017
lymphocyte proliferation GO:0046651 1 0.017
protein homooligomerization GO:0051260 3 0.017
homeostasis of number of cells GO:0048872 62 0.017
regulation of biomineral tissue development GO:0070167 2 0.017
regulation of cytoplasmic transport GO:1903649 4 0.017
organic substance catabolic process GO:1901575 28 0.017
synaptic growth at neuromuscular junction GO:0051124 2 0.017
protein targeting to nucleus GO:0044744 3 0.017
gtp metabolic process GO:0046039 4 0.017
neuroblast proliferation GO:0007405 2 0.017
oxidation reduction process GO:0055114 41 0.017
female sex differentiation GO:0046660 4 0.017
fatty acid oxidation GO:0019395 1 0.017
positive regulation of secretion by cell GO:1903532 1 0.017
regulation of macromolecule biosynthetic process GO:0010556 225 0.017
positive regulation of apoptotic signaling pathway GO:2001235 1 0.017
neuron projection morphogenesis GO:0048812 161 0.017
death GO:0016265 121 0.017
peptidyl lysine acetylation GO:0018394 2 0.017
regulation of synaptic plasticity GO:0048167 1 0.017
regulation of mitochondrion organization GO:0010821 1 0.017
membrane fusion GO:0061025 2 0.017
regulation of reactive oxygen species metabolic process GO:2000377 2 0.017
germ line stem cell maintenance GO:0030718 2 0.017
protein import GO:0017038 3 0.017
cellular respiration GO:0045333 3 0.016
catabolic process GO:0009056 32 0.016
positive regulation of neuron apoptotic process GO:0043525 1 0.016
regulation of protein transport GO:0051223 3 0.016
lipid storage GO:0019915 1 0.016
positive regulation of cellular metabolic process GO:0031325 94 0.016
lateral inhibition GO:0046331 1 0.016
liver development GO:0001889 96 0.016
regulation of carbohydrate metabolic process GO:0006109 4 0.016
response to abiotic stimulus GO:0009628 122 0.016
growth GO:0040007 174 0.016
regulation of signaling GO:0023051 235 0.016
cell projection morphogenesis GO:0048858 244 0.016
neuron development GO:0048666 262 0.016
cellular response to xenobiotic stimulus GO:0071466 35 0.016
regulation of cell development GO:0060284 100 0.016
regulation of protein localization to nucleus GO:1900180 2 0.016
embryonic organ development GO:0048568 381 0.016
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.016
protein acylation GO:0043543 3 0.015
positive regulation of stress activated mapk cascade GO:0032874 3 0.015
compound eye development GO:0048749 2 0.015
regulation of programmed cell death GO:0043067 101 0.015
regulation of extrinsic apoptotic signaling pathway GO:2001236 3 0.015
regulation of stem cell differentiation GO:2000736 4 0.015
cellular response to stress GO:0033554 62 0.015
cellular response to starvation GO:0009267 1 0.015
peptide transport GO:0015833 1 0.015
regulation of metal ion transport GO:0010959 4 0.015
amine metabolic process GO:0009308 2 0.015
neurotransmitter secretion GO:0007269 2 0.015
positive regulation of i kappab kinase nf kappab signaling GO:0043123 3 0.015
regulation of cellular amine metabolic process GO:0033238 0 0.015
response to corticosteroid GO:0031960 1 0.015
lipid metabolic process GO:0006629 52 0.015
organonitrogen compound metabolic process GO:1901564 74 0.015
protein acetylation GO:0006473 2 0.015
cellular protein modification process GO:0006464 100 0.015
cellular component morphogenesis GO:0032989 336 0.015
peptidyl serine modification GO:0018209 2 0.015
leukocyte homeostasis GO:0001776 2 0.015
hematopoietic or lymphoid organ development GO:0048534 191 0.015
negative regulation of protein serine threonine kinase activity GO:0071901 2 0.015
stem cell maintenance GO:0019827 4 0.015
response to nutrient GO:0007584 3 0.015
meiotic cell cycle process GO:1903046 3 0.015
positive regulation of neuron death GO:1901216 1 0.014
centrosome organization GO:0051297 1 0.014
establishment of synaptic vesicle localization GO:0097480 1 0.014
regulation of intracellular protein transport GO:0033157 3 0.014
dna catabolic process GO:0006308 1 0.014
centrosome cycle GO:0007098 1 0.014
system process GO:0003008 185 0.014
hemopoiesis GO:0030097 183 0.014
regulation of nervous system development GO:0051960 90 0.014
guanosine containing compound catabolic process GO:1901069 2 0.014
positive regulation of response to stimulus GO:0048584 80 0.014
protein modification process GO:0036211 100 0.014
blood vessel development GO:0001568 246 0.014
positive regulation of cellular catabolic process GO:0031331 3 0.014
type b pancreatic cell development GO:0003323 4 0.014
mitotic dna integrity checkpoint GO:0044774 4 0.014
retina development in camera type eye GO:0060041 146 0.014
cellular response to oxygen levels GO:0071453 1 0.014
regulation of canonical wnt signaling pathway GO:0060828 34 0.014
regulation of cellular amino acid metabolic process GO:0006521 0 0.014
cell death GO:0008219 121 0.014
taxis GO:0042330 109 0.014
carboxylic acid catabolic process GO:0046395 3 0.014
developmental growth GO:0048589 166 0.014
extrinsic apoptotic signaling pathway in absence of ligand GO:0097192 1 0.014
regulation of production of molecular mediator of immune response GO:0002700 1 0.014
melanin metabolic process GO:0006582 2 0.014
regulation of stem cell proliferation GO:0072091 2 0.014
antimicrobial humoral response GO:0019730 2 0.014
fatty acid beta oxidation GO:0006635 1 0.013
renal system development GO:0072001 94 0.013
regulation of anatomical structure size GO:0090066 33 0.013
positive regulation of translation GO:0045727 1 0.013
cellular component assembly GO:0022607 170 0.013
hormone biosynthetic process GO:0042446 3 0.013
regulation of protein modification by small protein conjugation or removal GO:1903320 3 0.013
developmental programmed cell death GO:0010623 4 0.013
regulation of cell morphogenesis involved in differentiation GO:0010769 38 0.013
regulation of receptor activity GO:0010469 2 0.013
response to xenobiotic stimulus GO:0009410 45 0.013
regulation of collateral sprouting in absence of injury GO:0048696 4 0.013
regulation of purine nucleotide catabolic process GO:0033121 2 0.013
regulation of nucleocytoplasmic transport GO:0046822 2 0.013
regulation of cellular component organization GO:0051128 86 0.013
positive regulation of immune effector process GO:0002699 3 0.013
regulation of jun kinase activity GO:0043506 3 0.013
chemotaxis GO:0006935 104 0.013
cellular response to chemical stimulus GO:0070887 157 0.013
small molecule catabolic process GO:0044282 3 0.013
double strand break repair via homologous recombination GO:0000724 1 0.013
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.013
cellular response to decreased oxygen levels GO:0036294 1 0.013
development of primary female sexual characteristics GO:0046545 4 0.012
regulation of nucleoside metabolic process GO:0009118 2 0.012
programmed cell death GO:0012501 119 0.012
positive regulation of signaling GO:0023056 56 0.012
regulation of neurotransmitter transport GO:0051588 1 0.012
organic acid metabolic process GO:0006082 31 0.012
stem cell division GO:0017145 1 0.012
regulation of meiotic cell cycle GO:0051445 1 0.012
regulation of skeletal muscle tissue development GO:0048641 4 0.012
inositol lipid mediated signaling GO:0048017 2 0.012
recombinational repair GO:0000725 1 0.012
response to stress GO:0006950 263 0.012
multi organism process GO:0051704 134 0.012
regulation of wound healing GO:0061041 2 0.012
response to radiation GO:0009314 51 0.012
regulation of protein targeting GO:1903533 2 0.012
positive regulation of cell activation GO:0050867 1 0.012
actin filament based movement GO:0030048 1 0.012
cellular lipid catabolic process GO:0044242 3 0.012
positive regulation of muscle organ development GO:0048636 1 0.012
adherens junction organization GO:0034332 4 0.012
tissue remodeling GO:0048771 4 0.012
regulation of cytokine production GO:0001817 3 0.012
sensory organ development GO:0007423 393 0.012
regulation of molecular function GO:0065009 70 0.012
regulation of bone mineralization GO:0030500 2 0.012
hormone transport GO:0009914 2 0.012
negative regulation of reproductive process GO:2000242 3 0.012
membrane invagination GO:0010324 1 0.012
canonical wnt signaling pathway GO:0060070 48 0.012
digestive tract development GO:0048565 265 0.012
release of sequestered calcium ion into cytosol GO:0051209 3 0.012
regulation of reproductive process GO:2000241 4 0.012
tube morphogenesis GO:0035239 349 0.012
myeloid cell homeostasis GO:0002262 56 0.012
regulation of inflammatory response GO:0050727 2 0.012
response to glucocorticoid GO:0051384 1 0.011
regulation of calcium dependent cell cell adhesion GO:0046586 1 0.011
negative regulation of defense response GO:0031348 2 0.011
phosphatidylinositol mediated signaling GO:0048015 2 0.011
embryonic organ morphogenesis GO:0048562 274 0.011
cardiac atrium development GO:0003230 4 0.011
positive regulation of cellular amine metabolic process GO:0033240 0 0.011
determination of left right asymmetry in diencephalon GO:0035462 4 0.011
regulation of anatomical structure morphogenesis GO:0022603 130 0.011
regulation of response to stimulus GO:0048583 269 0.011
notochord development GO:0030903 54 0.011
homeostatic process GO:0042592 142 0.011
synaptic vesicle transport GO:0048489 1 0.011
positive regulation of lymphocyte mediated immunity GO:0002708 1 0.011
regulation of phosphorus metabolic process GO:0051174 43 0.011
regulation of extrinsic apoptotic signaling pathway in absence of ligand GO:2001239 1 0.011
regulation of protein binding GO:0043393 3 0.011
osteoclast differentiation GO:0030316 1 0.011
regulation of cellular carbohydrate metabolic process GO:0010675 4 0.011
defense response GO:0006952 47 0.011
regulation of neurotransmitter secretion GO:0046928 1 0.011
cellular amine metabolic process GO:0044106 2 0.011
single organism membrane fusion GO:0044801 2 0.011
sensory perception of chemical stimulus GO:0007606 3 0.011
neuron projection development GO:0031175 180 0.011
head development GO:0060322 303 0.011
cellular component biogenesis GO:0044085 178 0.011
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 4 0.011
production of molecular mediator of immune response GO:0002440 2 0.011
cytokinetic process GO:0032506 2 0.011
forebrain cell migration GO:0021885 1 0.011
small gtpase mediated signal transduction GO:0007264 8 0.011
regulation of neuron projection development GO:0010975 40 0.011
positive regulation of dna metabolic process GO:0051054 1 0.011
positive regulation of lipid metabolic process GO:0045834 1 0.011
adult behavior GO:0030534 2 0.011
positive regulation of cell communication GO:0010647 56 0.011
regulation of jak stat cascade GO:0046425 3 0.011
regulation of dendrite development GO:0050773 3 0.011
regulation of apoptotic process GO:0042981 98 0.011
axon guidance GO:0007411 86 0.011
regulation of protein ubiquitination GO:0031396 3 0.011
myeloid cell differentiation GO:0030099 86 0.010
ribosomal small subunit biogenesis GO:0042274 2 0.010
gastrulation GO:0007369 208 0.010
cellular amino acid metabolic process GO:0006520 7 0.010
kidney development GO:0001822 92 0.010
regulation of hormone secretion GO:0046883 2 0.010
regulation of cell growth GO:0001558 29 0.010
dna biosynthetic process GO:0071897 3 0.010
positive regulation of stem cell proliferation GO:2000648 1 0.010
cellular response to light stimulus GO:0071482 4 0.010
response to ketone GO:1901654 1 0.010
b cell differentiation GO:0030183 1 0.010
enzyme linked receptor protein signaling pathway GO:0007167 106 0.010
keratinocyte differentiation GO:0030216 0 0.010
mesenchymal cell proliferation GO:0010463 1 0.010
negative regulation of metabolic process GO:0009892 86 0.010
regulation of phosphate metabolic process GO:0019220 43 0.010

eif4e3 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 0 0.037
inherited metabolic disorder DOID:655 0 0.037
disease of anatomical entity DOID:7 0 0.025
musculoskeletal system disease DOID:17 0 0.013
cancer DOID:162 0 0.013
disease of cellular proliferation DOID:14566 0 0.013