Danio rerio

29 known processes

elovl4a

elongation of very long chain fatty acids (FEN1/Elo2, SUR4/Elo3, yeast)-like 4a

(Aliases: MGC73341,zgc:73341)

elovl4a biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cellular response to lipopolysaccharide GO:0071222 3 0.240
signal transduction GO:0007165 455 0.223
hematopoietic or lymphoid organ development GO:0048534 191 0.220
small molecule metabolic process GO:0044281 77 0.199
regulation of response to stimulus GO:0048583 269 0.191
single organism biosynthetic process GO:0044711 71 0.167
phosphorus metabolic process GO:0006793 109 0.159
immune system process GO:0002376 241 0.142
larval development GO:0002164 2 0.138
cellular nitrogen compound metabolic process GO:0034641 290 0.137
activation of immune response GO:0002253 9 0.127
regulation of signal transduction GO:0009966 225 0.122
cellular aromatic compound metabolic process GO:0006725 295 0.121
regulation of cellular metabolic process GO:0031323 320 0.110
cellular ketone metabolic process GO:0042180 11 0.108
maintenance of location GO:0051235 4 0.105
i kappab kinase nf kappab signaling GO:0007249 4 0.102
regulation of i kappab kinase nf kappab signaling GO:0043122 4 0.099
negative regulation of biological process GO:0048519 304 0.097
organonitrogen compound metabolic process GO:1901564 74 0.097
cell surface receptor signaling pathway GO:0007166 325 0.091
hemopoiesis GO:0030097 183 0.088
organic substance biosynthetic process GO:1901576 289 0.086
regulation of protein transport GO:0051223 3 0.084
organic cyclic compound biosynthetic process GO:1901362 223 0.083
regulation of cell communication GO:0010646 232 0.081
regulation of cellular ketone metabolic process GO:0010565 7 0.078
immune response regulating signaling pathway GO:0002764 5 0.075
nitrogen compound metabolic process GO:0006807 319 0.071
positive regulation of camp biosynthetic process GO:0030819 2 0.070
regulation of primary metabolic process GO:0080090 311 0.069
regulation of establishment of protein localization GO:0070201 4 0.067
intracellular signal transduction GO:0035556 85 0.066
generation of neurons GO:0048699 385 0.065
leukocyte proliferation GO:0070661 1 0.064
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.063
aromatic compound biosynthetic process GO:0019438 217 0.060
positive regulation of i kappab kinase nf kappab signaling GO:0043123 3 0.058
locomotion GO:0040011 313 0.058
tube morphogenesis GO:0035239 349 0.057
immune system development GO:0002520 191 0.057
positive regulation of biological process GO:0048518 253 0.057
regulation of developmental process GO:0050793 247 0.057
heterocycle metabolic process GO:0046483 290 0.057
cellular amine metabolic process GO:0044106 2 0.056
single organism metabolic process GO:0044710 217 0.056
regulation of multicellular organismal process GO:0051239 277 0.056
immune response activating signal transduction GO:0002757 5 0.056
regulation of nitrogen compound metabolic process GO:0051171 251 0.051
positive regulation of cellular process GO:0048522 201 0.048
positive regulation of cellular metabolic process GO:0031325 94 0.047
aging GO:0007568 2 0.047
developmental growth GO:0048589 166 0.047
ribose phosphate biosynthetic process GO:0046390 20 0.047
neuron differentiation GO:0030182 353 0.046
reactive oxygen species metabolic process GO:0072593 6 0.046
multicellular organism growth GO:0035264 4 0.046
regulation of metabolic process GO:0019222 359 0.045
regulation of cytokine production GO:0001817 3 0.045
regulation of biosynthetic process GO:0009889 250 0.044
amine metabolic process GO:0009308 2 0.044
biosynthetic process GO:0009058 294 0.044
regulation of binding GO:0051098 3 0.043
regulation of cellular amine metabolic process GO:0033238 0 0.042
cellular macromolecule metabolic process GO:0044260 391 0.042
cellular response to molecule of bacterial origin GO:0071219 3 0.042
organic cyclic compound metabolic process GO:1901360 301 0.042
response to biotic stimulus GO:0009607 97 0.041
regulation of intracellular protein transport GO:0033157 3 0.041
positive regulation of signal transduction GO:0009967 56 0.041
regulation of tyrosine phosphorylation of stat protein GO:0042509 1 0.041
embryonic organ development GO:0048568 381 0.040
regulation of multicellular organism growth GO:0040014 4 0.040
negative regulation of protein phosphorylation GO:0001933 4 0.040
cellular component movement GO:0006928 335 0.040
morphogenesis of an epithelium GO:0002009 333 0.039
regulation of cell activation GO:0050865 1 0.039
cellular protein metabolic process GO:0044267 129 0.038
synaptic growth at neuromuscular junction GO:0051124 2 0.038
cellular response to biotic stimulus GO:0071216 3 0.038
positive regulation of rna metabolic process GO:0051254 59 0.037
positive regulation of jnk cascade GO:0046330 3 0.037
regulation of tyrosine phosphorylation of stat3 protein GO:0042516 1 0.036
fatty acid biosynthetic process GO:0006633 4 0.036
heterocycle biosynthetic process GO:0018130 215 0.036
blood vessel development GO:0001568 246 0.036
nucleobase containing compound metabolic process GO:0006139 274 0.036
regulation of signaling GO:0023051 235 0.036
gtp metabolic process GO:0046039 4 0.035
tyrosine phosphorylation of stat protein GO:0007260 1 0.035
regulation of cellular biosynthetic process GO:0031326 245 0.034
gland development GO:0048732 143 0.034
positive regulation of stress activated mapk cascade GO:0032874 3 0.034
regulation of protein localization to nucleus GO:1900180 2 0.033
negative regulation of cellular process GO:0048523 283 0.033
regulation of gene expression GO:0010468 265 0.033
rna biosynthetic process GO:0032774 181 0.033
regulation of synapse assembly GO:0051963 3 0.033
stem cell maintenance GO:0019827 4 0.032
energy reserve metabolic process GO:0006112 2 0.032
positive regulation of cytokine production GO:0001819 2 0.032
protein localization to plasma membrane GO:0072659 1 0.032
positive regulation of multicellular organismal process GO:0051240 52 0.032
regulation of response to stress GO:0080134 36 0.032
positive regulation of cell activation GO:0050867 1 0.032
regulation of cell differentiation GO:0045595 142 0.031
lipid storage GO:0019915 1 0.031
regulation of biological quality GO:0065008 263 0.031
phosphate containing compound metabolic process GO:0006796 108 0.031
oxoacid metabolic process GO:0043436 31 0.030
nucleotide biosynthetic process GO:0009165 21 0.030
phagocytosis GO:0006909 3 0.029
cellular localization GO:0051641 97 0.029
toll like receptor signaling pathway GO:0002224 4 0.028
response to other organism GO:0051707 97 0.028
transcription dna templated GO:0006351 181 0.028
regulation of cellular amino acid metabolic process GO:0006521 0 0.028
mononuclear cell proliferation GO:0032943 1 0.028
vasculature development GO:0001944 278 0.028
cellular amide metabolic process GO:0043603 4 0.028
regulation of intracellular signal transduction GO:1902531 57 0.028
defense response GO:0006952 47 0.028
skeletal system development GO:0001501 181 0.027
heart development GO:0007507 313 0.027
cellular nitrogen compound biosynthetic process GO:0044271 218 0.027
cognition GO:0050890 1 0.027
b cell activation GO:0042113 2 0.027
programmed cell death GO:0012501 119 0.027
positive regulation of camp metabolic process GO:0030816 2 0.027
single organism intracellular transport GO:1902582 25 0.027
cellular component assembly GO:0022607 170 0.027
regulation of synapse organization GO:0050807 3 0.026
regulation of inflammatory response GO:0050727 2 0.026
cartilage development GO:0051216 96 0.026
regulation of programmed cell death GO:0043067 101 0.026
organic acid metabolic process GO:0006082 31 0.026
negative regulation of multicellular organismal process GO:0051241 69 0.026
lymphocyte proliferation GO:0046651 1 0.026
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.025
action potential GO:0001508 19 0.025
gene expression GO:0010467 252 0.025
positive regulation of cytosolic calcium ion concentration GO:0007204 4 0.025
regulation of multicellular organismal development GO:2000026 223 0.025
regulation of receptor activity GO:0010469 2 0.025
regulation of cytoplasmic transport GO:1903649 4 0.025
establishment of endothelial barrier GO:0061028 3 0.024
regulation of protein binding GO:0043393 3 0.024
organophosphate biosynthetic process GO:0090407 23 0.024
intracellular transport GO:0046907 32 0.024
regulation of transcription dna templated GO:0006355 213 0.024
negative regulation of protein kinase activity GO:0006469 4 0.023
neurotransmitter secretion GO:0007269 2 0.023
stem cell proliferation GO:0072089 4 0.023
embryonic organ morphogenesis GO:0048562 274 0.023
regulation of neural precursor cell proliferation GO:2000177 3 0.023
regulation of cell shape GO:0008360 1 0.023
defense response to bacterium GO:0042742 22 0.023
cellular response to external stimulus GO:0071496 2 0.022
response to vitamin b3 GO:0033552 2 0.022
regionalization GO:0003002 274 0.022
rna metabolic process GO:0016070 219 0.022
positive regulation of catabolic process GO:0009896 4 0.022
wnt signaling pathway GO:0016055 80 0.022
central nervous system development GO:0007417 387 0.022
regulation of nucleocytoplasmic transport GO:0046822 2 0.022
antimicrobial humoral response GO:0019730 2 0.022
neurotransmitter transport GO:0006836 2 0.022
purine nucleotide biosynthetic process GO:0006164 20 0.022
golgi vesicle transport GO:0048193 3 0.022
transcription from rna polymerase ii promoter GO:0006366 80 0.022
multicellular organismal signaling GO:0035637 22 0.022
cell death GO:0008219 121 0.022
response to organic substance GO:0010033 153 0.022
regulation of apoptotic process GO:0042981 98 0.022
positive regulation of developmental process GO:0051094 50 0.021
response to chemical GO:0042221 320 0.021
production of molecular mediator of immune response GO:0002440 2 0.021
exocytosis GO:0006887 1 0.021
carboxylic acid metabolic process GO:0019752 22 0.021
growth GO:0040007 174 0.021
head development GO:0060322 303 0.021
connective tissue development GO:0061448 99 0.021
neuroblast proliferation GO:0007405 2 0.021
carbohydrate derivative metabolic process GO:1901135 61 0.020
erythrocyte homeostasis GO:0034101 55 0.020
organophosphate metabolic process GO:0019637 37 0.020
regulation of cell death GO:0010941 103 0.020
type i interferon biosynthetic process GO:0045351 1 0.020
cell proliferation GO:0008283 80 0.020
regulation of immune response GO:0050776 14 0.020
regulation of reproductive process GO:2000241 4 0.020
response to stress GO:0006950 263 0.020
regulation of rna biosynthetic process GO:2001141 213 0.020
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.019
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.019
regulation of localization GO:0032879 104 0.019
regulation of reactive oxygen species metabolic process GO:2000377 2 0.019
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 4 0.019
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.019
positive regulation of signaling GO:0023056 56 0.019
death GO:0016265 121 0.019
immune response GO:0006955 28 0.019
response to endogenous stimulus GO:0009719 83 0.019
modification dependent protein catabolic process GO:0019941 3 0.019
regulation of protein import into nucleus GO:0042306 2 0.018
lipid biosynthetic process GO:0008610 22 0.018
cellular response to chemical stimulus GO:0070887 157 0.018
protein targeting to nucleus GO:0044744 3 0.018
positive regulation of cell cycle GO:0045787 3 0.018
homeostatic process GO:0042592 142 0.018
localization of cell GO:0051674 244 0.018
guanosine containing compound metabolic process GO:1901068 4 0.018
cell motility GO:0048870 244 0.018
type i interferon production GO:0032606 2 0.018
cellular biosynthetic process GO:0044249 286 0.018
regulation of macromolecule biosynthetic process GO:0010556 225 0.018
nucleocytoplasmic transport GO:0006913 4 0.018
nuclear import GO:0051170 3 0.018
cellular component morphogenesis GO:0032989 336 0.018
negative regulation of kinase activity GO:0033673 4 0.018
protein localization GO:0008104 40 0.017
transmission of nerve impulse GO:0019226 19 0.017
positive regulation of cellular biosynthetic process GO:0031328 68 0.017
protein secretion GO:0009306 1 0.017
nucleobase containing compound biosynthetic process GO:0034654 205 0.017
regulation of protein targeting GO:1903533 2 0.017
protein localization to nucleus GO:0034504 3 0.017
epithelial tube morphogenesis GO:0060562 148 0.017
regulation of metal ion transport GO:0010959 4 0.017
ion transmembrane transport GO:0034220 91 0.017
protein import into nucleus GO:0006606 3 0.017
ion transport GO:0006811 114 0.017
response to external biotic stimulus GO:0043207 97 0.016
phosphorylation GO:0016310 69 0.016
erythrocyte differentiation GO:0030218 54 0.016
retina morphogenesis in camera type eye GO:0060042 79 0.016
nucleic acid templated transcription GO:0097659 181 0.016
extrinsic apoptotic signaling pathway GO:0097191 3 0.016
post golgi vesicle mediated transport GO:0006892 1 0.016
positive regulation of dna metabolic process GO:0051054 1 0.016
regulation of cyclin dependent protein serine threonine kinase activity GO:0000079 1 0.016
determination of bilateral symmetry GO:0009855 204 0.016
regulation of rna metabolic process GO:0051252 224 0.016
mitochondrial transport GO:0006839 2 0.016
regulation of organ growth GO:0046620 3 0.015
neuronal action potential GO:0019228 18 0.015
adherens junction organization GO:0034332 4 0.015
guanosine containing compound catabolic process GO:1901069 2 0.015
cellular protein modification process GO:0006464 100 0.015
activation of mapk activity GO:0000187 3 0.015
epithelial cell differentiation GO:0030855 116 0.015
specification of symmetry GO:0009799 204 0.015
positive regulation of cellular catabolic process GO:0031331 3 0.015
establishment of protein localization to organelle GO:0072594 4 0.015
negative regulation of response to stimulus GO:0048585 104 0.015
regulation of protein metabolic process GO:0051246 56 0.015
membrane fusion GO:0061025 2 0.015
regulation of nucleic acid templated transcription GO:1903506 213 0.015
energy homeostasis GO:0097009 3 0.015
long chain fatty acid biosynthetic process GO:0042759 1 0.015
Zebrafish
protein import GO:0017038 3 0.014
cellular response to organic substance GO:0071310 105 0.014
gastrulation GO:0007369 208 0.014
modification dependent macromolecule catabolic process GO:0043632 3 0.014
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.014
establishment of localization GO:0051234 244 0.014
purine containing compound metabolic process GO:0072521 29 0.014
negative regulation of developmental process GO:0051093 65 0.014
regulation of nervous system development GO:0051960 90 0.014
cell migration GO:0016477 237 0.014
ribonucleotide biosynthetic process GO:0009260 20 0.014
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.014
ubiquitin dependent protein catabolic process GO:0006511 3 0.014
regulation of cell development GO:0060284 100 0.014
fin development GO:0033333 77 0.014
triglyceride homeostasis GO:0070328 2 0.014
single organism localization GO:1902578 225 0.013
positive regulation of tyrosine phosphorylation of stat protein GO:0042531 1 0.013
positive regulation of metabolic process GO:0009893 108 0.013
peripheral nervous system neuron development GO:0048935 22 0.013
macromolecule modification GO:0043412 111 0.013
tyrosine phosphorylation of stat3 protein GO:0042503 1 0.013
liver development GO:0001889 96 0.013
myeloid cell differentiation GO:0030099 86 0.013
macromolecular complex disassembly GO:0032984 1 0.013
regulation of stem cell differentiation GO:2000736 4 0.013
multi organism process GO:0051704 134 0.013
nuclear export GO:0051168 1 0.013
regulation of protein modification by small protein conjugation or removal GO:1903320 3 0.013
cardiac atrium morphogenesis GO:0003209 2 0.013
negative regulation of synapse assembly GO:0051964 2 0.013
response to external stimulus GO:0009605 264 0.013
b cell mediated immunity GO:0019724 3 0.013
nucleobase containing small molecule metabolic process GO:0055086 32 0.013
regulation of macromolecule metabolic process GO:0060255 317 0.013
hepaticobiliary system development GO:0061008 98 0.013
regulation of cell proliferation GO:0042127 37 0.013
nucleic acid metabolic process GO:0090304 244 0.013
cellular macromolecule biosynthetic process GO:0034645 224 0.013
cellular response to nutrient levels GO:0031669 2 0.013
gtp catabolic process GO:0006184 2 0.013
positive regulation of tyrosine phosphorylation of stat3 protein GO:0042517 1 0.012
compound eye development GO:0048749 2 0.012
lipid metabolic process GO:0006629 52 0.012
negative regulation of macromolecule metabolic process GO:0010605 76 0.012
convergent extension GO:0060026 118 0.012
regulation of protein catabolic process GO:0042176 1 0.012
rna transport GO:0050658 2 0.012
regulation of calcium ion transport GO:0051924 2 0.012
regulation of gtp catabolic process GO:0033124 2 0.012
proteasomal protein catabolic process GO:0010498 2 0.012
b cell differentiation GO:0030183 1 0.012
spermatid differentiation GO:0048515 2 0.012
endothelium development GO:0003158 25 0.012
pattern recognition receptor signaling pathway GO:0002221 5 0.012
cellular lipid metabolic process GO:0044255 36 0.012
positive regulation of transcription dna templated GO:0045893 57 0.012
digestive tract development GO:0048565 265 0.012
meiosis i GO:0007127 1 0.012
single organism transport GO:0044765 206 0.012
homeostasis of number of cells GO:0048872 62 0.012
secondary metabolic process GO:0019748 3 0.012
sequestering of calcium ion GO:0051208 3 0.012
regulation of nucleoside metabolic process GO:0009118 2 0.012
ribonucleotide metabolic process GO:0009259 27 0.012
meiotic cell cycle process GO:1903046 3 0.012
cellular response to endogenous stimulus GO:0071495 68 0.012
chordate embryonic development GO:0043009 271 0.012
camp biosynthetic process GO:0006171 11 0.012
positive regulation of cellular amine metabolic process GO:0033240 0 0.012
positive regulation of stress activated protein kinase signaling cascade GO:0070304 3 0.012
ribose phosphate metabolic process GO:0019693 27 0.012
nuclear transport GO:0051169 4 0.011
ensheathment of neurons GO:0007272 18 0.011
single organism membrane fusion GO:0044801 2 0.011
cellular protein catabolic process GO:0044257 4 0.011
leukocyte homeostasis GO:0001776 2 0.011
regulation of growth GO:0040008 42 0.011
response to ketone GO:1901654 1 0.011
positive regulation of neural precursor cell proliferation GO:2000179 1 0.011
cell morphogenesis GO:0000902 289 0.011
nucleoside phosphate metabolic process GO:0006753 28 0.011
negative regulation of defense response GO:0031348 2 0.011
lateral line system development GO:0048925 76 0.011
regulation of jak stat cascade GO:0046425 3 0.011
positive regulation of cellular protein metabolic process GO:0032270 22 0.011
positive regulation of immune effector process GO:0002699 3 0.011
negative regulation of reproductive process GO:2000242 3 0.011
embryo development ending in birth or egg hatching GO:0009792 271 0.011
regulation of synaptic plasticity GO:0048167 1 0.011
cellular amino acid metabolic process GO:0006520 7 0.011
negative regulation of nitrogen compound metabolic process GO:0051172 59 0.011
inner ear development GO:0048839 126 0.011
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.011
regulation of response to biotic stimulus GO:0002831 2 0.011
regulation of wnt signaling pathway GO:0030111 53 0.011
positive regulation of response to stimulus GO:0048584 80 0.011
regulation of catalytic activity GO:0050790 55 0.011
single organism nuclear import GO:1902593 3 0.011
cyclic purine nucleotide metabolic process GO:0052652 18 0.011
negative regulation of translation GO:0017148 1 0.011
apoptotic process GO:0006915 116 0.011
positive regulation of gtp catabolic process GO:0033126 1 0.011
lipid homeostasis GO:0055088 3 0.011
immunoglobulin mediated immune response GO:0016064 3 0.011
response to oxygen containing compound GO:1901700 55 0.011
regulation of phosphate metabolic process GO:0019220 43 0.011
regulation of transcription from rna polymerase ii promoter GO:0006357 114 0.011
innate immune response GO:0045087 13 0.010
purine nucleotide metabolic process GO:0006163 27 0.010
determination of left right symmetry GO:0007368 179 0.010
protein complex disassembly GO:0043241 1 0.010
ovulation cycle GO:0042698 2 0.010
protein metabolic process GO:0019538 183 0.010
negative regulation of multi organism process GO:0043901 3 0.010
cellular component biogenesis GO:0044085 178 0.010
synaptic vesicle localization GO:0097479 1 0.010
positive regulation of macromolecule biosynthetic process GO:0010557 59 0.010
digestive tract morphogenesis GO:0048546 231 0.010
blood vessel morphogenesis GO:0048514 216 0.010
regulation of neural retina development GO:0061074 2 0.010
oxidation reduction process GO:0055114 41 0.010
long chain fatty acid metabolic process GO:0001676 1 0.010
Zebrafish
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 68 0.010
positive regulation of rna biosynthetic process GO:1902680 57 0.010
neuron development GO:0048666 262 0.010
alcohol biosynthetic process GO:0046165 2 0.010

elovl4a disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.031
Human
nervous system disease DOID:863 0 0.031
Human
sensory system disease DOID:0050155 0 0.023
Human
retinal disease DOID:5679 0 0.019
Human
eye and adnexa disease DOID:1492 0 0.019
Human
eye disease DOID:5614 0 0.019
Human
cancer DOID:162 0 0.012
disease of cellular proliferation DOID:14566 0 0.012
organ system cancer DOID:0050686 0 0.011