Danio rerio

22 known processes

enc1

ectodermal-neural cortex (with BTB-like domain)

(Aliases: id:ibd3303,wu:fi15g12)

enc1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
regulation of signaling GO:0023051 235 0.451
determination of bilateral symmetry GO:0009855 204 0.331
protein modification process GO:0036211 100 0.292
locomotion GO:0040011 313 0.252
larval development GO:0002164 2 0.201
skeletal system development GO:0001501 181 0.199
dorsal ventral pattern formation GO:0009953 125 0.184
developmental growth GO:0048589 166 0.183
embryonic organ morphogenesis GO:0048562 274 0.180
digestive system development GO:0055123 289 0.169
protein phosphorylation GO:0006468 47 0.156
hepaticobiliary system development GO:0061008 98 0.152
negative regulation of cellular process GO:0048523 283 0.147
regulation of multicellular organism growth GO:0040014 4 0.139
hormone biosynthetic process GO:0042446 3 0.139
regulation of metabolic process GO:0019222 359 0.129
organic acid metabolic process GO:0006082 31 0.117
embryonic heart tube morphogenesis GO:0003143 108 0.110
protein metabolic process GO:0019538 183 0.110
cilium morphogenesis GO:0060271 85 0.103
signal transduction GO:0007165 455 0.101
embryonic organ development GO:0048568 381 0.099
negative regulation of biological process GO:0048519 304 0.094
specification of symmetry GO:0009799 204 0.090
erk1 and erk2 cascade GO:0070371 4 0.090
convergent extension GO:0060026 118 0.089
cellular macromolecule metabolic process GO:0044260 391 0.088
cell surface receptor signaling pathway GO:0007166 325 0.088
gamete generation GO:0007276 33 0.087
epiboly GO:0090504 41 0.087
cell death GO:0008219 121 0.087
regulation of response to stimulus GO:0048583 269 0.085
morphogenesis of an epithelium GO:0002009 333 0.084
macromolecule modification GO:0043412 111 0.080
negative regulation of cellular metabolic process GO:0031324 77 0.078
positive regulation of jun kinase activity GO:0043507 2 0.078
negative regulation of cell differentiation GO:0045596 46 0.078
positive regulation of apoptotic process GO:0043065 29 0.077
negative regulation of protein phosphorylation GO:0001933 4 0.075
cellular biosynthetic process GO:0044249 286 0.075
cell migration GO:0016477 237 0.074
embryonic cranial skeleton morphogenesis GO:0048701 90 0.073
maintenance of location GO:0051235 4 0.069
regulation of protein metabolic process GO:0051246 56 0.069
regionalization GO:0003002 274 0.068
meiotic nuclear division GO:0007126 4 0.066
formation of primary germ layer GO:0001704 62 0.065
regulation of protein phosphorylation GO:0001932 18 0.065
cellular ketone metabolic process GO:0042180 11 0.064
regulation of embryonic development GO:0045995 47 0.063
eye field cell fate commitment involved in camera type eye formation GO:0060898 3 0.062
regulation of cell communication GO:0010646 232 0.062
hematopoietic or lymphoid organ development GO:0048534 191 0.062
aging GO:0007568 2 0.061
regulation of cellular metabolic process GO:0031323 320 0.060
skeletal system morphogenesis GO:0048705 102 0.058
regulation of developmental process GO:0050793 247 0.057
digestive tract morphogenesis GO:0048546 231 0.057
regulation of cell activation GO:0050865 1 0.056
positive regulation of programmed cell death GO:0043068 29 0.056
regulation of cell death GO:0010941 103 0.056
optic placode formation GO:0001743 4 0.055
heterocycle biosynthetic process GO:0018130 215 0.055
sensory perception GO:0007600 39 0.054
immune system development GO:0002520 191 0.053
negative chemotaxis GO:0050919 1 0.052
determination of dorsal ventral asymmetry GO:0048262 34 0.051
oxoacid metabolic process GO:0043436 31 0.050
positive regulation of multicellular organismal process GO:0051240 52 0.050
tube closure GO:0060606 1 0.050
liver development GO:0001889 96 0.049
cellular component movement GO:0006928 335 0.048
cell motility GO:0048870 244 0.047
cellular protein modification process GO:0006464 100 0.047
regulation of primary metabolic process GO:0080090 311 0.046
heart development GO:0007507 313 0.045
urogenital system development GO:0001655 97 0.045
cellular process involved in reproduction in multicellular organism GO:0022412 28 0.045
single organism metabolic process GO:0044710 217 0.044
microtubule based process GO:0007017 60 0.042
negative regulation of protein kinase activity GO:0006469 4 0.041
neuron differentiation GO:0030182 353 0.041
multicellular organism growth GO:0035264 4 0.041
carboxylic acid metabolic process GO:0019752 22 0.040
cilium organization GO:0044782 71 0.040
transport GO:0006810 220 0.040
developmental growth involved in morphogenesis GO:0060560 86 0.040
embryo development ending in birth or egg hatching GO:0009792 271 0.040
lipid storage GO:0019915 1 0.040
camera type eye development GO:0043010 222 0.039
lateral line development GO:0048882 66 0.039
cellular component biogenesis GO:0044085 178 0.038
wnt signaling pathway GO:0016055 80 0.038
wnt signaling pathway involved in digestive tract morphogenesis GO:0044333 4 0.038
extrinsic apoptotic signaling pathway GO:0097191 3 0.038
negative regulation of kinase activity GO:0033673 4 0.037
organic cyclic compound biosynthetic process GO:1901362 223 0.036
kidney development GO:0001822 92 0.036
cytoskeleton organization GO:0007010 96 0.036
tube morphogenesis GO:0035239 349 0.036
single organism localization GO:1902578 225 0.035
retinal ganglion cell axon guidance GO:0031290 35 0.035
glucose homeostasis GO:0042593 1 0.034
heart looping GO:0001947 94 0.034
multi organism process GO:0051704 134 0.034
extrinsic apoptotic signaling pathway in absence of ligand GO:0097192 1 0.034
enzyme linked receptor protein signaling pathway GO:0007167 106 0.033
cellular protein metabolic process GO:0044267 129 0.033
cell migration involved in gastrulation GO:0042074 79 0.033
eye development GO:0001654 277 0.033
striated muscle tissue development GO:0014706 110 0.033
multi organism reproductive process GO:0044703 36 0.032
positive regulation of map kinase activity GO:0043406 3 0.032
regulation of apoptotic process GO:0042981 98 0.032
regulation of phosphorus metabolic process GO:0051174 43 0.032
microtubule cytoskeleton organization GO:0000226 33 0.031
embryonic skeletal system morphogenesis GO:0048704 93 0.031
phosphate containing compound metabolic process GO:0006796 108 0.031
chordate embryonic development GO:0043009 271 0.031
positive regulation of canonical wnt signaling pathway GO:0090263 4 0.031
regulation of biosynthetic process GO:0009889 250 0.031
reproductive process GO:0022414 40 0.030
sensory system development GO:0048880 76 0.030
regulation of multicellular organismal development GO:2000026 223 0.030
establishment of protein localization to organelle GO:0072594 4 0.030
neural tube development GO:0021915 62 0.030
mesoderm development GO:0007498 88 0.030
intracellular signal transduction GO:0035556 85 0.030
mononuclear cell proliferation GO:0032943 1 0.029
regulation of cellular amine metabolic process GO:0033238 0 0.029
protein targeting to nucleus GO:0044744 3 0.029
response to radiation GO:0009314 51 0.029
negative regulation of wnt signaling pathway GO:0030178 30 0.029
regulation of cell differentiation GO:0045595 142 0.029
positive regulation of biological process GO:0048518 253 0.029
cellular nitrogen compound biosynthetic process GO:0044271 218 0.029
alcohol biosynthetic process GO:0046165 2 0.028
programmed cell death GO:0012501 119 0.028
pancreas development GO:0031016 84 0.028
central nervous system development GO:0007417 387 0.028
receptor internalization GO:0031623 2 0.028
neuron projection morphogenesis GO:0048812 161 0.028
regulation of dna replication GO:0006275 3 0.027
multicellular organismal reproductive process GO:0048609 35 0.027
response to stress GO:0006950 263 0.027
small molecule metabolic process GO:0044281 77 0.027
negative regulation of signaling GO:0023057 96 0.027
regulation of cellular protein metabolic process GO:0032268 52 0.027
response to external stimulus GO:0009605 264 0.027
heart jogging GO:0003146 40 0.026
cell projection organization GO:0030030 284 0.026
developmental maturation GO:0021700 34 0.026
response to organic substance GO:0010033 153 0.026
Zebrafish
positive regulation of cell death GO:0010942 29 0.026
regulation of bmp signaling pathway GO:0030510 39 0.026
spinal cord development GO:0021510 46 0.025
organic substance biosynthetic process GO:1901576 289 0.025
skeletal muscle tissue development GO:0007519 67 0.025
lymphocyte proliferation GO:0046651 1 0.025
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.025
regulation of macromolecule metabolic process GO:0060255 317 0.025
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 50 0.025
regulation of canonical wnt signaling pathway GO:0060828 34 0.024
multicellular organism reproduction GO:0032504 35 0.024
single organism transport GO:0044765 206 0.024
cell part morphogenesis GO:0032990 246 0.024
phagocytosis GO:0006909 3 0.024
positive regulation of catabolic process GO:0009896 4 0.024
apoptotic process GO:0006915 116 0.024
immune system process GO:0002376 241 0.024
cell activation GO:0001775 16 0.024
b cell differentiation GO:0030183 1 0.024
muscle cell differentiation GO:0042692 139 0.024
rna biosynthetic process GO:0032774 181 0.024
response to lipid GO:0033993 60 0.024
Zebrafish
generation of neurons GO:0048699 385 0.023
regulation of purine nucleotide catabolic process GO:0033121 2 0.023
positive regulation of cell substrate adhesion GO:0010811 1 0.023
morphogenesis of an epithelial sheet GO:0002011 49 0.023
rho protein signal transduction GO:0007266 5 0.023
nucleobase containing compound metabolic process GO:0006139 274 0.023
cellular amino acid biosynthetic process GO:0008652 2 0.023
macromolecular complex subunit organization GO:0043933 74 0.023
regulation of macromolecule biosynthetic process GO:0010556 225 0.023
sulfur compound metabolic process GO:0006790 13 0.023
cell morphogenesis GO:0000902 289 0.022
regulation of programmed cell death GO:0043067 101 0.022
cilium assembly GO:0042384 58 0.022
regulation of circadian rhythm GO:0042752 4 0.022
regulation of chondrocyte differentiation GO:0032330 1 0.022
endoderm development GO:0007492 49 0.022
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.022
autophagy GO:0006914 4 0.022
regulation of establishment of protein localization GO:0070201 4 0.021
regulation of protein transport GO:0051223 3 0.021
epiboly involved in gastrulation with mouth forming second GO:0055113 35 0.021
cellular response to endogenous stimulus GO:0071495 68 0.021
Zebrafish
oocyte differentiation GO:0009994 14 0.021
stem cell differentiation GO:0048863 117 0.021
cell projection morphogenesis GO:0048858 244 0.021
regulation of cellular ketone metabolic process GO:0010565 7 0.021
regulation of hormone metabolic process GO:0032350 6 0.021
phosphorylation GO:0016310 69 0.021
cellular amino acid metabolic process GO:0006520 7 0.020
lateral line system development GO:0048925 76 0.020
spemann organizer formation GO:0060061 10 0.020
reproduction GO:0000003 40 0.020
regulation of wnt signaling pathway involved in digestive tract morphogenesis GO:2000056 2 0.020
nucleic acid metabolic process GO:0090304 244 0.020
myeloid cell differentiation GO:0030099 86 0.019
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.019
phosphorus metabolic process GO:0006793 109 0.019
nitrogen compound metabolic process GO:0006807 319 0.019
radial glial cell differentiation GO:0060019 2 0.019
mesenchyme development GO:0060485 127 0.019
protein localization to nucleus GO:0034504 3 0.019
response to oxygen containing compound GO:1901700 55 0.019
Zebrafish
determination of heart left right asymmetry GO:0061371 117 0.018
bmp signaling pathway GO:0030509 52 0.018
hemopoiesis GO:0030097 183 0.018
camera type eye morphogenesis GO:0048593 108 0.018
sexual reproduction GO:0019953 36 0.018
regulation of signal transduction GO:0009966 225 0.018
neuron development GO:0048666 262 0.018
optic placode formation involved in camera type eye formation GO:0046619 3 0.018
single organism nuclear import GO:1902593 3 0.018
digestive tract development GO:0048565 265 0.018
morphogenesis of embryonic epithelium GO:0016331 30 0.017
b cell activation GO:0042113 2 0.017
regulation of protein kinase activity GO:0045859 15 0.017
regulation of alcohol biosynthetic process GO:1902930 1 0.017
kupffer s vesicle development GO:0070121 50 0.017
osteoclast differentiation GO:0030316 1 0.017
embryonic skeletal system development GO:0048706 97 0.017
cellular response to external stimulus GO:0071496 2 0.017
cell maturation GO:0048469 23 0.017
regulation of phosphorylation GO:0042325 26 0.017
oocyte development GO:0048599 14 0.017
establishment of localization GO:0051234 244 0.016
positive regulation of cell adhesion GO:0045785 1 0.016
positive regulation of response to stimulus GO:0048584 80 0.016
regulation of myeloid cell differentiation GO:0045637 8 0.016
regulation of cell cycle GO:0051726 52 0.016
transcription dna templated GO:0006351 181 0.016
gland development GO:0048732 143 0.016
nuclear transport GO:0051169 4 0.016
ear morphogenesis GO:0042471 64 0.016
regulation of jun kinase activity GO:0043506 3 0.015
regulation of wnt signaling pathway GO:0030111 53 0.015
limbic system development GO:0021761 16 0.015
organonitrogen compound metabolic process GO:1901564 74 0.015
regulation of cellular amino acid metabolic process GO:0006521 0 0.015
cell cycle process GO:0022402 53 0.015
single organism organelle organization GO:1902589 199 0.015
oocyte maturation GO:0001556 4 0.015
epithelial tube morphogenesis GO:0060562 148 0.015
epithelial cell differentiation GO:0030855 116 0.015
death GO:0016265 121 0.015
regulation of phosphate metabolic process GO:0019220 43 0.015
regulation of rna metabolic process GO:0051252 224 0.015
response to endogenous stimulus GO:0009719 83 0.015
Zebrafish
epithelial cell proliferation involved in liver morphogenesis GO:0072575 2 0.015
regulation of neural precursor cell proliferation GO:2000177 3 0.014
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 68 0.014
homeostatic process GO:0042592 142 0.014
ear development GO:0043583 127 0.014
gastrulation GO:0007369 208 0.014
response to hexose GO:0009746 3 0.014
regulation of biological quality GO:0065008 263 0.014
protein polyubiquitination GO:0000209 4 0.014
centrosome organization GO:0051297 1 0.014
ras protein signal transduction GO:0007265 7 0.014
negative regulation of cell communication GO:0010648 96 0.014
positive regulation of cell cycle GO:0045787 3 0.014
cellular amine metabolic process GO:0044106 2 0.013
localization of cell GO:0051674 244 0.013
negative regulation of fibroblast growth factor receptor signaling pathway GO:0040037 6 0.013
cellular component assembly GO:0022607 170 0.013
protein import into nucleus GO:0006606 3 0.013
regulation of stem cell differentiation GO:2000736 4 0.013
negative regulation of mitosis GO:0045839 3 0.013
cognition GO:0050890 1 0.013
regulation of protein modification process GO:0031399 29 0.013
stem cell division GO:0017145 1 0.013
bmp signaling pathway involved in heart development GO:0061312 15 0.013
regulation of establishment or maintenance of cell polarity GO:0032878 2 0.013
cortical cytoskeleton organization GO:0030865 1 0.013
transcription from rna polymerase iii promoter GO:0006383 1 0.013
negative regulation of protein transport GO:0051224 3 0.013
biosynthetic process GO:0009058 294 0.013
positive regulation of signaling GO:0023056 56 0.013
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 20 0.013
response to light stimulus GO:0009416 46 0.012
regulation of protein catabolic process GO:0042176 1 0.012
cellular macromolecule biosynthetic process GO:0034645 224 0.012
cellular hormone metabolic process GO:0034754 19 0.012
synaptic target recognition GO:0008039 1 0.012
nuclear import GO:0051170 3 0.012
primary neural tube formation GO:0014020 1 0.012
centrosome cycle GO:0007098 1 0.012
microtubule organizing center organization GO:0031023 1 0.012
cell proliferation in forebrain GO:0021846 3 0.012
protein import GO:0017038 3 0.012
posterior lateral line system development GO:0048915 46 0.012
organelle organization GO:0006996 227 0.012
leukocyte proliferation GO:0070661 1 0.012
growth GO:0040007 174 0.012
regulation of response to nutrient levels GO:0032107 1 0.012
ectodermal placode development GO:0071696 37 0.012
positive regulation of myeloid cell differentiation GO:0045639 2 0.012
negative regulation of response to stimulus GO:0048585 104 0.012
convergent extension involved in gastrulation GO:0060027 71 0.012
sensory organ morphogenesis GO:0090596 200 0.012
regulation of nucleoside metabolic process GO:0009118 2 0.012
nucleocytoplasmic transport GO:0006913 4 0.011
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.011
cell cycle GO:0007049 93 0.011
positive regulation of multi organism process GO:0043902 3 0.011
oogenesis GO:0048477 14 0.011
regulation of multicellular organismal process GO:0051239 277 0.011
regulation of gene expression GO:0010468 265 0.011
regulation of gtp catabolic process GO:0033124 2 0.011
cell growth GO:0016049 57 0.011
mitotic cell cycle GO:0000278 64 0.011
ovarian follicle development GO:0001541 2 0.011
tissue regeneration GO:0042246 74 0.011
membrane invagination GO:0010324 1 0.011
positive regulation of cellular component biogenesis GO:0044089 3 0.011
response to osmotic stress GO:0006970 11 0.011
proteasomal protein catabolic process GO:0010498 2 0.011
negative regulation of protein serine threonine kinase activity GO:0071901 2 0.011
positive regulation of biosynthetic process GO:0009891 68 0.011
mucopolysaccharide metabolic process GO:1903510 2 0.011
response to corticosteroid GO:0031960 1 0.011
taxis GO:0042330 109 0.011
positive regulation of ras protein signal transduction GO:0046579 1 0.011
regulation of cellular component organization GO:0051128 86 0.011
inner ear morphogenesis GO:0042472 63 0.011
stem cell maintenance GO:0019827 4 0.011
negative regulation of signal transduction GO:0009968 94 0.011
small gtpase mediated signal transduction GO:0007264 8 0.011
axon extension GO:0048675 45 0.011
regulation of developmental growth GO:0048638 38 0.010
axon development GO:0061564 166 0.010
regulation of protein import into nucleus GO:0042306 2 0.010
regulation of erk1 and erk2 cascade GO:0070372 4 0.010
central nervous system neuron differentiation GO:0021953 74 0.010
negative regulation of nucleobase containing compound metabolic process GO:0045934 59 0.010
positive regulation of transport GO:0051050 2 0.010
post anal tail morphogenesis GO:0036342 19 0.010
cytokinesis GO:0000910 3 0.010
cellular response to starvation GO:0009267 1 0.010
angioblast cell migration GO:0035476 9 0.010
retina development in camera type eye GO:0060041 146 0.010

enc1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
physical disorder DOID:0080015 0 0.015