Danio rerio

45 known processes

eng2a

engrailed 2a

(Aliases: Zf-en,MGC193943,ZF-EN-2,ENG-2,eng2,MGC193941)

eng2a biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
midbrain hindbrain boundary development GO:0030917 23 0.994
generation of neurons GO:0048699 385 0.989
Zebrafish Mouse Fly
anterior commissure morphogenesis GO:0021960 3 0.985
Fly
midbrain hindbrain boundary morphogenesis GO:0021555 5 0.984
neuroblast fate determination GO:0007400 1 0.982
Fly
cellular component movement GO:0006928 335 0.979
Fly
rostrocaudal neural tube patterning GO:0021903 29 0.976
cell differentiation in spinal cord GO:0021515 40 0.972
nucleic acid metabolic process GO:0090304 244 0.972
Mouse Worm Fly
neuron development GO:0048666 262 0.967
Mouse Fly
stem cell fate determination GO:0048867 1 0.967
Fly
neuron fate commitment GO:0048663 26 0.965
Zebrafish
regionalization GO:0003002 274 0.964
regulation of developmental process GO:0050793 247 0.961
neuron fate specification GO:0048665 20 0.960
neural tube patterning GO:0021532 33 0.956
locomotion GO:0040011 313 0.949
Worm Fly
nucleobase containing compound biosynthetic process GO:0034654 205 0.947
Mouse Worm Fly
epidermal cell fate specification GO:0009957 4 0.943
Worm
neuroblast differentiation GO:0014016 1 0.930
Fly
neural tube development GO:0021915 62 0.926
somatic muscle development GO:0007525 4 0.881
cellular component morphogenesis GO:0032989 336 0.876
Fly
neuron differentiation GO:0030182 353 0.869
Zebrafish Mouse Fly
regulation of macromolecule metabolic process GO:0060255 317 0.866
Mouse Worm Fly
regulation of biosynthetic process GO:0009889 250 0.859
Mouse Worm Fly
neuron projection guidance GO:0097485 86 0.843
Fly
hindbrain formation GO:0021576 3 0.837
chordate embryonic development GO:0043009 271 0.833
developmental programmed cell death GO:0010623 4 0.828
cell morphogenesis GO:0000902 289 0.824
Fly
nucleic acid templated transcription GO:0097659 181 0.823
Mouse Worm Fly
regulation of cellular biosynthetic process GO:0031326 245 0.822
Mouse Worm Fly
rna biosynthetic process GO:0032774 181 0.818
Mouse Worm Fly
cellular nitrogen compound biosynthetic process GO:0044271 218 0.818
Mouse Worm Fly
cellular nitrogen compound metabolic process GO:0034641 290 0.817
Mouse Worm Fly
regulation of rna metabolic process GO:0051252 224 0.780
Mouse Worm Fly
skin development GO:0043588 54 0.780
Worm
cell projection morphogenesis GO:0048858 244 0.780
Fly
organic cyclic compound metabolic process GO:1901360 301 0.757
Mouse Worm Fly
oligodendrocyte cell fate specification GO:0021778 4 0.744
cardiocyte differentiation GO:0035051 44 0.742
angiogenesis GO:0001525 158 0.741
neuron fate determination GO:0048664 2 0.729
embryonic camera type eye development GO:0031076 29 0.716
lipid storage GO:0019915 1 0.709
nucleobase containing compound metabolic process GO:0006139 274 0.703
Mouse Worm Fly
cerebellum formation GO:0021588 2 0.701
cell fate commitment GO:0045165 99 0.697
cellular aromatic compound metabolic process GO:0006725 295 0.688
Mouse Worm Fly
ventral midline development GO:0007418 13 0.682
Fly
cell projection organization GO:0030030 284 0.681
Fly
brain development GO:0007420 293 0.681
neuron projection morphogenesis GO:0048812 161 0.677
Fly
anterior posterior pattern specification GO:0009952 152 0.661
embryonic organ morphogenesis GO:0048562 274 0.651
heterocycle metabolic process GO:0046483 290 0.647
Mouse Worm Fly
epidermis development GO:0008544 48 0.643
Worm
cell proliferation in forebrain GO:0021846 3 0.640
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.639
Fly
apoptotic process involved in development GO:1902742 2 0.637
positive regulation of epithelial cell differentiation GO:0030858 2 0.626
response to external stimulus GO:0009605 264 0.625
Fly
apoptotic process involved in morphogenesis GO:0060561 2 0.613
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.610
Mouse Worm Fly
neuron projection development GO:0031175 180 0.606
Fly
regulation of multicellular organismal development GO:2000026 223 0.600
regulation of nervous system development GO:0051960 90 0.599
abducens nucleus development GO:0021742 2 0.595
maintenance of location GO:0051235 4 0.594
somitogenesis GO:0001756 87 0.591
embryo development ending in birth or egg hatching GO:0009792 271 0.589
regulation of gene expression GO:0010468 265 0.587
Mouse Worm Fly
macromolecule biosynthetic process GO:0009059 227 0.586
Mouse Worm Fly
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.576
Mouse Worm Fly
axonogenesis GO:0007409 152 0.575
Fly
fourth ventricle development GO:0021592 8 0.563
organic cyclic compound biosynthetic process GO:1901362 223 0.551
Mouse Worm Fly
extraocular skeletal muscle development GO:0002074 3 0.551
cellular biosynthetic process GO:0044249 286 0.547
Mouse Worm Fly
heterocycle biosynthetic process GO:0018130 215 0.543
Mouse Worm Fly
axon guidance GO:0007411 86 0.543
Fly
positive regulation of metabolic process GO:0009893 108 0.541
Mouse Worm Fly
cell fate specification GO:0001708 68 0.535
regulation of macromolecule biosynthetic process GO:0010556 225 0.532
Mouse Worm Fly
rna metabolic process GO:0016070 219 0.531
Mouse Worm Fly
gene expression GO:0010467 252 0.529
Mouse Worm Fly
cardiac muscle tissue development GO:0048738 48 0.522
regulation of neuron differentiation GO:0045664 56 0.508
ventral spinal cord interneuron fate commitment GO:0060579 3 0.506
spinal cord oligodendrocyte cell fate specification GO:0021530 2 0.506
embryonic skeletal system development GO:0048706 97 0.496
cell morphogenesis involved in differentiation GO:0000904 195 0.495
Fly
positive regulation of nucleobase containing compound metabolic process GO:0045935 69 0.493
Mouse Worm Fly
somite specification GO:0001757 12 0.491
negative regulation of cellular process GO:0048523 283 0.488
Worm Fly
negative regulation of nucleobase containing compound metabolic process GO:0045934 59 0.483
Worm Fly
regulation of cellular metabolic process GO:0031323 320 0.474
Mouse Worm Fly
organic substance biosynthetic process GO:1901576 289 0.468
Mouse Worm Fly
positive regulation of biological process GO:0048518 253 0.443
Mouse Worm Fly
pancreas development GO:0031016 84 0.439
sensory organ morphogenesis GO:0090596 200 0.436
sensory system development GO:0048880 76 0.433
cell motility GO:0048870 244 0.429
hair cell differentiation GO:0035315 32 0.426
regulation of rna biosynthetic process GO:2001141 213 0.417
Mouse Worm Fly
muscle organ development GO:0007517 101 0.417
blood vessel morphogenesis GO:0048514 216 0.411
regulation of neurogenesis GO:0050767 87 0.408
heart development GO:0007507 313 0.405
regulation of primary metabolic process GO:0080090 311 0.393
Mouse Worm Fly
nitrogen compound metabolic process GO:0006807 319 0.388
Mouse Worm Fly
somite development GO:0061053 96 0.385
chemotaxis GO:0006935 104 0.382
Fly
photoreceptor cell fate commitment GO:0046552 1 0.377
embryonic cranial skeleton morphogenesis GO:0048701 90 0.371
positive regulation of cellular process GO:0048522 201 0.369
Mouse Worm Fly
negative regulation of cellular macromolecule biosynthetic process GO:2000113 48 0.369
Worm Fly
posterior lateral line neuromast hair cell differentiation GO:0048923 8 0.367
positive regulation of nucleic acid templated transcription GO:1903508 57 0.365
Mouse Worm Fly
negative regulation of biological process GO:0048519 304 0.363
Worm Fly
heart morphogenesis GO:0003007 156 0.363
central nervous system neuron differentiation GO:0021953 74 0.362
Fly
photoreceptor cell fate specification GO:0043704 1 0.359
negative regulation of cellular biosynthetic process GO:0031327 55 0.356
Worm Fly
embryonic skeletal system morphogenesis GO:0048704 93 0.355
aromatic compound biosynthetic process GO:0019438 217 0.353
Mouse Worm Fly
regulation of multicellular organismal process GO:0051239 277 0.352
central nervous system neuron development GO:0021954 29 0.351
Fly
cerebellum development GO:0021549 17 0.349
glial cell fate specification GO:0021780 4 0.346
larval development GO:0002164 2 0.338
anterior head development GO:0097065 2 0.332
blood vessel development GO:0001568 246 0.332
epithelial cell differentiation GO:0030855 116 0.315
Worm
regulation of nucleic acid templated transcription GO:1903506 213 0.309
Mouse Worm Fly
regulation of metabolic process GO:0019222 359 0.307
Mouse Worm Fly
multicellular organism reproduction GO:0032504 35 0.306
axon development GO:0061564 166 0.306
Fly
dorsal ventral pattern formation GO:0009953 125 0.306
positive regulation of macromolecule metabolic process GO:0010604 93 0.303
Mouse Worm Fly
cellular macromolecule biosynthetic process GO:0034645 224 0.302
Mouse Worm Fly
embryonic camera type eye formation GO:0060900 10 0.302
ear development GO:0043583 127 0.302
regulation of cell development GO:0060284 100 0.302
pronephric glomerulus development GO:0039021 13 0.300
endocrine system development GO:0035270 65 0.299
mediolateral intercalation GO:0060031 3 0.297
response to chemical GO:0042221 320 0.295
Fly
regulation of cell communication GO:0010646 232 0.292
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.286
Mouse Worm Fly
cell migration GO:0016477 237 0.286
neural plate development GO:0001840 10 0.285
negative regulation of anterior neural cell fate commitment of the neural plate GO:0022001 1 0.278
central nervous system development GO:0007417 387 0.275
regulation of transcription dna templated GO:0006355 213 0.275
Mouse Worm Fly
cerebellum morphogenesis GO:0021587 10 0.264
retina layer formation GO:0010842 24 0.262
eye morphogenesis GO:0048592 144 0.254
regulation of transcription from rna polymerase ii promoter GO:0006357 114 0.249
Mouse Worm Fly
camera type eye morphogenesis GO:0048593 108 0.248
muscle cell differentiation GO:0042692 139 0.247
ventral spinal cord interneuron differentiation GO:0021514 12 0.245
aorta morphogenesis GO:0035909 3 0.243
regulation of nitrogen compound metabolic process GO:0051171 251 0.241
Mouse Worm Fly
metencephalon development GO:0022037 27 0.239
endocrine pancreas development GO:0031018 27 0.236
pigmentation GO:0043473 85 0.229
biosynthetic process GO:0009058 294 0.219
Mouse Worm Fly
posterior lateral line system development GO:0048915 46 0.216
defense response to other organism GO:0098542 33 0.209
Fly
auditory receptor cell fate commitment GO:0009912 4 0.207
transcription from rna polymerase ii promoter GO:0006366 80 0.204
Mouse Worm Fly
stem cell fate commitment GO:0048865 1 0.203
Fly
ameboidal type cell migration GO:0001667 143 0.202
transcription dna templated GO:0006351 181 0.195
Mouse Worm Fly
cellular macromolecule metabolic process GO:0044260 391 0.195
Mouse Worm Fly
skeletal muscle organ development GO:0060538 78 0.195
cell proliferation in hindbrain GO:0021534 4 0.194
gamete generation GO:0007276 33 0.193
regulation of cardiac chamber formation GO:1901210 2 0.192
central nervous system neuron axonogenesis GO:0021955 18 0.192
Fly
peripheral nervous system development GO:0007422 55 0.192
lateral line ganglion development GO:0048890 2 0.191
multicellular organismal reproductive process GO:0048609 35 0.189
striated muscle cell differentiation GO:0051146 129 0.183
mesoderm development GO:0007498 88 0.183
embryonic viscerocranium morphogenesis GO:0048703 52 0.182
head development GO:0060322 303 0.182
midbrain development GO:0030901 28 0.180
positive regulation of gene expression GO:0010628 71 0.179
Mouse Worm Fly
positive regulation of rna metabolic process GO:0051254 59 0.177
Mouse Worm Fly
neuromast development GO:0048884 46 0.176
reproductive structure development GO:0048608 5 0.173
Fly
lateral line system development GO:0048925 76 0.169
forebrain regionalization GO:0021871 4 0.164
regulation of heart growth GO:0060420 2 0.164
embryonic organ development GO:0048568 381 0.163
negative regulation of macromolecule metabolic process GO:0010605 76 0.159
Worm Fly
single organism reproductive process GO:0044702 40 0.158
Fly
skeletal muscle tissue development GO:0007519 67 0.157
localization of cell GO:0051674 244 0.155
axonal fasciculation GO:0007413 11 0.152
organelle organization GO:0006996 227 0.152
multi organism reproductive process GO:0044703 36 0.152
cell fate specification involved in pattern specification GO:0060573 3 0.151
stem cell differentiation GO:0048863 117 0.150
Fly
cell differentiation in hindbrain GO:0021533 5 0.150
cardiac muscle cell differentiation GO:0055007 30 0.150
regulation of wnt signaling pathway calcium modulating pathway GO:0008591 3 0.147
forebrain neuron fate commitment GO:0021877 1 0.145
regulation of anterior head development GO:2000742 2 0.143
sensory organ development GO:0007423 393 0.141
peripheral nervous system neuron differentiation GO:0048934 28 0.140
neuromast mantle cell differentiation GO:0048888 1 0.138
positive regulation of rna biosynthetic process GO:1902680 57 0.138
Mouse Worm Fly
motor neuron axon guidance GO:0008045 23 0.137
lateral line development GO:0048882 66 0.137
spinal cord patterning GO:0021511 6 0.135
aorta development GO:0035904 4 0.134
positive regulation of biosynthetic process GO:0009891 68 0.131
Mouse Worm Fly
positive regulation of neural precursor cell proliferation GO:2000179 1 0.131
regeneration GO:0031099 91 0.130
ear morphogenesis GO:0042471 64 0.130
positive regulation of cellular metabolic process GO:0031325 94 0.129
Mouse Worm Fly
developmental induction GO:0031128 10 0.127
gland development GO:0048732 143 0.124
proepicardium development GO:0003342 4 0.124
negative regulation of biosynthetic process GO:0009890 55 0.124
Worm Fly
negative regulation of transcription dna templated GO:0045892 45 0.123
Worm Fly
specification of symmetry GO:0009799 204 0.123
definitive hemopoiesis GO:0060216 18 0.122
muscle structure development GO:0061061 196 0.121
hindbrain development GO:0030902 91 0.121
Mouse
taxis GO:0042330 109 0.121
Fly
multicellular organism growth GO:0035264 4 0.121
signal transduction GO:0007165 455 0.119
cerebellar granule cell differentiation GO:0021707 3 0.118
inner ear receptor cell development GO:0060119 20 0.118
photoreceptor cell differentiation GO:0046530 55 0.118
muscle tissue development GO:0060537 110 0.116
response to stress GO:0006950 263 0.116
Fly
cell cell signaling GO:0007267 52 0.114
hepatic duct development GO:0061011 2 0.113
negative regulation of sequestering of calcium ion GO:0051283 4 0.111
neural plate anterior posterior regionalization GO:0021999 8 0.111
positive regulation of cellular biosynthetic process GO:0031328 68 0.111
Mouse Worm Fly
negative regulation of gene expression GO:0010629 65 0.110
Worm Fly
regulation of mechanoreceptor differentiation GO:0045631 1 0.110
single organism organelle organization GO:1902589 199 0.109
behavior GO:0007610 74 0.108
embryonic camera type eye morphogenesis GO:0048596 19 0.107
release of sequestered calcium ion into cytosol GO:0051209 3 0.105
pronephros morphogenesis GO:0072114 14 0.104
cell differentiation involved in kidney development GO:0061005 13 0.104
inner ear receptor cell differentiation GO:0060113 29 0.102
auditory receptor cell fate determination GO:0042668 2 0.101
embryonic pectoral fin morphogenesis GO:0035118 24 0.100
negative regulation of macromolecule biosynthetic process GO:0010558 48 0.100
Worm Fly
developmental process involved in reproduction GO:0003006 27 0.100
Fly
regulation of response to stimulus GO:0048583 269 0.100
spinal cord association neuron differentiation GO:0021527 1 0.099
auditory receptor cell differentiation GO:0042491 15 0.099
inner ear development GO:0048839 126 0.099
regulation of wnt signaling pathway involved in digestive tract morphogenesis GO:2000056 2 0.096
forebrain neuron development GO:0021884 7 0.096
apoptotic process GO:0006915 116 0.096
post embryonic organ development GO:0048569 4 0.096
Fly
regulation of biological quality GO:0065008 263 0.096
ectodermal placode development GO:0071696 37 0.094
membrane fusion GO:0061025 2 0.094
Worm
ventricular cardiac muscle tissue morphogenesis GO:0055010 2 0.093
cerebellar cortex formation GO:0021697 5 0.091
regulation of cell differentiation GO:0045595 142 0.090
regulation of stem cell proliferation GO:0072091 2 0.090
camera type eye photoreceptor cell differentiation GO:0060219 19 0.087
regulation of endopeptidase activity GO:0052548 23 0.086
blood circulation GO:0008015 87 0.085
ventral spinal cord interneuron specification GO:0021521 3 0.085
wnt signaling pathway GO:0016055 80 0.085
immune system process GO:0002376 241 0.084
pancreatic a cell development GO:0003322 2 0.084
neural plate morphogenesis GO:0001839 7 0.084
spinal cord motor neuron cell fate specification GO:0021520 8 0.083
central nervous system projection neuron axonogenesis GO:0021952 15 0.083
Fly
embryonic heart tube formation GO:0003144 1 0.082
organelle assembly GO:0070925 110 0.082
inner ear receptor cell fate commitment GO:0060120 4 0.081
negative regulation of nuclear division GO:0051784 3 0.079
hindbrain morphogenesis GO:0021575 22 0.078
nephron development GO:0072006 31 0.078
pons development GO:0021548 11 0.077
regulation of inner ear receptor cell differentiation GO:2000980 1 0.077
forebrain anterior posterior pattern specification GO:0021797 3 0.077
negative regulation of anterior neural cell fate commitment of the neural plate by wnt signaling pathway GO:0022002 1 0.076
brain morphogenesis GO:0048854 18 0.076
forebrain development GO:0030900 96 0.076
Fly
glial cell migration GO:0008347 3 0.076
regulation of multicellular organism growth GO:0040014 4 0.075
body morphogenesis GO:0010171 16 0.074
Worm
forebrain neuron differentiation GO:0021879 14 0.073
forebrain morphogenesis GO:0048853 6 0.073
embryonic appendage morphogenesis GO:0035113 30 0.072
neural plate pattern specification GO:0060896 12 0.072
digestive system development GO:0055123 289 0.071
reproductive process GO:0022414 40 0.071
Fly
growth GO:0040007 174 0.070
cardiac chamber formation GO:0003207 4 0.070
mesodermal cell fate specification GO:0007501 12 0.070
cerebellar granular layer formation GO:0021684 3 0.069
embryonic limb morphogenesis GO:0030326 2 0.069
positive regulation of macromolecule biosynthetic process GO:0010557 59 0.068
Mouse Worm Fly
forebrain dorsal ventral pattern formation GO:0021798 1 0.067
thalamus development GO:0021794 6 0.067
regulation of photoreceptor cell differentiation GO:0046532 2 0.067
neural retina development GO:0003407 49 0.066
developmental growth GO:0048589 166 0.065
positive regulation of transcription dna templated GO:0045893 57 0.064
Mouse Worm Fly
regulation of retina development in camera type eye GO:1902866 2 0.063
cerebellar cortex development GO:0021695 5 0.063
eye development GO:0001654 277 0.063
thrombocyte differentiation GO:0002574 4 0.063
pectoral fin development GO:0033339 50 0.061
endocardium morphogenesis GO:0003160 4 0.059
myofibril assembly GO:0030239 48 0.058
regulation of epithelial cell proliferation GO:0050678 3 0.058
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 20 0.058
chemical homeostasis GO:0048878 49 0.058
negative regulation of protein maturation GO:1903318 10 0.057
negative regulation of cysteine type endopeptidase activity GO:2000117 8 0.055
neural crest cell differentiation GO:0014033 72 0.055
appendage development GO:0048736 80 0.055
Fly
death GO:0016265 121 0.055
pronephric glomerulus morphogenesis GO:0035775 6 0.054
programmed cell death GO:0012501 119 0.054
sexual reproduction GO:0019953 36 0.053
glomerulus development GO:0032835 27 0.052
dorsal spinal cord development GO:0021516 1 0.052
regulation of epithelial cell differentiation GO:0030856 7 0.051
negative regulation of transcription from rna polymerase ii promoter GO:0000122 16 0.051
Worm Fly
embryonic eye morphogenesis GO:0048048 30 0.050
regulation of cell projection organization GO:0031344 44 0.050
neural precursor cell proliferation GO:0061351 20 0.050
mesenchymal cell differentiation GO:0048762 87 0.049
striated muscle tissue development GO:0014706 110 0.049
spinal cord anterior posterior patterning GO:0021512 1 0.049
stem cell development GO:0048864 82 0.049
glomerulus morphogenesis GO:0072102 7 0.049
type b pancreatic cell development GO:0003323 4 0.048
photoreceptor cell development GO:0042461 40 0.048
mechanoreceptor differentiation GO:0042490 37 0.048
response to other organism GO:0051707 97 0.048
Fly
olfactory lobe development GO:0021988 4 0.048
epidermal cell differentiation GO:0009913 36 0.048
Worm
vestibular receptor cell development GO:0060118 3 0.048
cell proliferation in midbrain GO:0033278 4 0.048
diencephalon development GO:0021536 58 0.047
pectoral fin morphogenesis GO:0035138 29 0.047
intracellular signal transduction GO:0035556 85 0.047
ventral spinal cord development GO:0021517 35 0.047
ectodermal placode morphogenesis GO:0071697 32 0.047
negative regulation of proteolysis GO:0045861 10 0.047
negative regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043154 7 0.046
neural tube formation GO:0001841 16 0.046
neuron neuron synaptic transmission GO:0007270 1 0.046
formation of anatomical boundary GO:0048859 14 0.045
Worm
tube morphogenesis GO:0035239 349 0.045
cell death GO:0008219 121 0.045
pharyngeal system development GO:0060037 18 0.045
regulation of programmed cell death GO:0043067 101 0.045
positive regulation of cell cycle GO:0045787 3 0.044
retina development in camera type eye GO:0060041 146 0.044
olfactory placode development GO:0071698 12 0.044
gliogenesis GO:0042063 45 0.044
neural crest cell development GO:0014032 62 0.043
central nervous system myelination GO:0022010 2 0.043
regulation of response to biotic stimulus GO:0002831 2 0.042
regulation of cell cycle GO:0051726 52 0.042
epithelial cell development GO:0002064 42 0.042
specification of organ identity GO:0010092 2 0.041
posterior lateral line development GO:0048916 38 0.041
septum transversum development GO:0003343 4 0.040
eye photoreceptor cell differentiation GO:0001754 45 0.040
polarized epithelial cell differentiation GO:0030859 4 0.040
innervation GO:0060384 3 0.040
cranial nerve development GO:0021545 42 0.040
autonomic nervous system development GO:0048483 19 0.040
erythrocyte differentiation GO:0030218 54 0.040
cell cycle GO:0007049 93 0.040
regulation of signaling GO:0023051 235 0.040
exocrine pancreas development GO:0031017 28 0.039
glandular epithelial cell differentiation GO:0002067 9 0.039
mesoderm morphogenesis GO:0048332 51 0.038
dorsal ventral axis specification GO:0009950 14 0.038
cell part morphogenesis GO:0032990 246 0.038
Fly
hematopoietic stem cell differentiation GO:0060218 20 0.038
spinal cord development GO:0021510 46 0.038
ventricular cardiac muscle tissue development GO:0003229 3 0.037
vasculature development GO:0001944 278 0.036
cartilage development GO:0051216 96 0.036
ventricular system development GO:0021591 12 0.036
otic vesicle development GO:0071599 42 0.036
dendrite guidance GO:0070983 0 0.036
reproductive system development GO:0061458 5 0.036
Fly
response to biotic stimulus GO:0009607 97 0.036
Fly
inner ear morphogenesis GO:0042472 63 0.036
regulation of catalytic activity GO:0050790 55 0.035
macromolecular complex subunit organization GO:0043933 74 0.035
heart growth GO:0060419 7 0.035
cardiogenic plate morphogenesis GO:0003142 1 0.035
vasculogenesis GO:0001570 41 0.035
pharyngeal muscle development GO:0043282 4 0.035
regulation of hydrolase activity GO:0051336 28 0.035
nephron tubule morphogenesis GO:0072078 1 0.035
cellular response to external stimulus GO:0071496 2 0.034
spinal cord dorsal ventral patterning GO:0021513 5 0.034
cell fate commitment involved in pattern specification GO:0060581 6 0.034
peripheral nervous system neuron development GO:0048935 22 0.033
axon extension GO:0048675 45 0.033
stem cell proliferation GO:0072089 4 0.033
regulation of neural precursor cell proliferation GO:2000177 3 0.032
establishment or maintenance of cell polarity GO:0007163 29 0.032
mesenchymal cell proliferation GO:0010463 1 0.032
cranial ganglion development GO:0061550 3 0.032
protein complex biogenesis GO:0070271 30 0.032
system process GO:0003008 185 0.032
neuron projection regeneration GO:0031102 16 0.032
skeletal muscle fiber development GO:0048741 35 0.031
glial cell differentiation GO:0010001 42 0.031
tube formation GO:0035148 25 0.031
hepatocyte proliferation GO:0072574 2 0.031
nephric duct development GO:0072176 13 0.031
primary neural tube formation GO:0014020 1 0.031
skeletal system morphogenesis GO:0048705 102 0.030
kidney rudiment formation GO:0072003 3 0.030
dendrite morphogenesis GO:0048813 5 0.030
nephric duct morphogenesis GO:0072178 7 0.030
multi organism process GO:0051704 134 0.030
Fly
positive regulation of cytosolic calcium ion concentration GO:0007204 4 0.030
positive regulation of neuron apoptotic process GO:0043525 1 0.030
heart process GO:0003015 71 0.030
embryonic epithelial tube formation GO:0001838 17 0.030
pancreatic d cell differentiation GO:0003311 2 0.029
striated muscle cell proliferation GO:0014855 7 0.029
mitotic cell cycle GO:0000278 64 0.029
otolith development GO:0048840 32 0.029
positive regulation of stem cell proliferation GO:2000648 1 0.029
otic placode formation GO:0043049 23 0.029
floor plate development GO:0033504 15 0.029
regulation of apoptotic process GO:0042981 98 0.028
cell surface receptor signaling pathway GO:0007166 325 0.028
regulation of axon guidance GO:1902667 8 0.028
positive regulation of neuron migration GO:2001224 2 0.028
neuron recognition GO:0008038 18 0.028
macromolecule localization GO:0033036 54 0.028
negative regulation of endopeptidase activity GO:0010951 10 0.028
negative regulation of nitrogen compound metabolic process GO:0051172 59 0.028
Worm Fly
epithelial cell proliferation involved in liver morphogenesis GO:0072575 2 0.028
negative regulation of rna biosynthetic process GO:1902679 45 0.027
Worm Fly
negative regulation of mitosis GO:0045839 3 0.027
morphogenesis of embryonic epithelium GO:0016331 30 0.027
response to fibroblast growth factor GO:0071774 22 0.027
negative regulation of protein processing GO:0010955 10 0.027
reproduction GO:0000003 40 0.027
locomotory behavior GO:0007626 34 0.027
negative regulation of wnt signaling pathway GO:0030178 30 0.027
positive regulation of programmed cell death GO:0043068 29 0.026
organonitrogen compound metabolic process GO:1901564 74 0.026
regulation of neuron projection development GO:0010975 40 0.026
canonical wnt signaling pathway GO:0060070 48 0.026
inositol lipid mediated signaling GO:0048017 2 0.026
negative regulation of metabolic process GO:0009892 86 0.026
Worm Fly
regulation of protein processing GO:0070613 10 0.026
synaptic transmission GO:0007268 35 0.026
endocardium formation GO:0060214 1 0.025
cell proliferation GO:0008283 80 0.025
regulation of cellular component organization GO:0051128 86 0.025
aging GO:0007568 2 0.025
organ growth GO:0035265 12 0.025
type b pancreatic cell differentiation GO:0003309 8 0.025
cardiac chamber development GO:0003205 19 0.025
protein kinase b signaling GO:0043491 9 0.024
negative regulation of developmental process GO:0051093 65 0.024
optic placode formation involved in camera type eye formation GO:0046619 3 0.024
antimicrobial humoral response GO:0019730 2 0.024
cellular component assembly involved in morphogenesis GO:0010927 107 0.024
kupffer s vesicle development GO:0070121 50 0.024
homeostatic process GO:0042592 142 0.024
posterior lateral line nerve development GO:0048918 8 0.023
mesenchyme development GO:0060485 127 0.023
response to hydrogen peroxide GO:0042542 3 0.023
response to external biotic stimulus GO:0043207 97 0.023
Fly
regulation of signal transduction GO:0009966 225 0.023
sequestering of metal ion GO:0051238 3 0.023
regulation of anatomical structure morphogenesis GO:0022603 130 0.022
forebrain midbrain boundary formation GO:0021905 1 0.022

eng2a disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
kidney disease DOID:557 0 0.224
disease of anatomical entity DOID:7 0 0.224
urinary system disease DOID:18 0 0.224