Danio rerio

34 known processes

eng2b

engrailed 2b

(Aliases: ZF-EN-1,en3,ENG-3,eng3)

eng2b biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
hindbrain formation GO:0021576 3 0.869
forebrain development GO:0030900 96 0.859
Fly
epidermis development GO:0008544 48 0.848
Worm
inner ear receptor cell differentiation GO:0060113 29 0.837
mechanoreceptor differentiation GO:0042490 37 0.833
brain development GO:0007420 293 0.832
midbrain hindbrain boundary morphogenesis GO:0021555 5 0.825
Zebrafish
sensory organ development GO:0007423 393 0.816
central nervous system development GO:0007417 387 0.813
hindbrain development GO:0030902 91 0.810
nucleic acid metabolic process GO:0090304 244 0.779
Worm Fly
regulation of transcription dna templated GO:0006355 213 0.745
Worm Fly
midbrain hindbrain boundary development GO:0030917 23 0.714
skin development GO:0043588 54 0.708
Worm
regionalization GO:0003002 274 0.703
regulation of metabolic process GO:0019222 359 0.691
Worm Fly
stem cell fate determination GO:0048867 1 0.682
Fly
transcription dna templated GO:0006351 181 0.681
Worm Fly
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.678
Worm Fly
neuroblast fate determination GO:0007400 1 0.673
Fly
hair cell differentiation GO:0035315 32 0.672
cellular biosynthetic process GO:0044249 286 0.660
Worm Fly
cellular nitrogen compound biosynthetic process GO:0044271 218 0.656
Worm Fly
rna biosynthetic process GO:0032774 181 0.638
Worm Fly
nucleic acid templated transcription GO:0097659 181 0.629
Worm Fly
hindbrain morphogenesis GO:0021575 22 0.614
chordate embryonic development GO:0043009 271 0.610
sensory organ morphogenesis GO:0090596 200 0.605
head development GO:0060322 303 0.604
pronephric glomerulus development GO:0039021 13 0.601
neuron fate determination GO:0048664 2 0.597
nucleobase containing compound biosynthetic process GO:0034654 205 0.589
Worm Fly
retina morphogenesis in camera type eye GO:0060042 79 0.573
posterior lateral line neuromast hair cell differentiation GO:0048923 8 0.562
regulation of biosynthetic process GO:0009889 250 0.555
Worm Fly
regulation of macromolecule metabolic process GO:0060255 317 0.554
Worm Fly
regulation of gene expression GO:0010468 265 0.552
Worm Fly
cerebellum formation GO:0021588 2 0.544
segment specification GO:0007379 12 0.535
embryo development ending in birth or egg hatching GO:0009792 271 0.533
central nervous system neuron differentiation GO:0021953 74 0.519
Fly
cellular aromatic compound metabolic process GO:0006725 295 0.497
Worm Fly
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.486
Worm Fly
regulation of transcription from rna polymerase ii promoter GO:0006357 114 0.481
Worm Fly
organic substance biosynthetic process GO:1901576 289 0.481
Worm Fly
pronephric nephron development GO:0039019 14 0.478
cell proliferation in forebrain GO:0021846 3 0.473
rostrocaudal neural tube patterning GO:0021903 29 0.461
regulation of macromolecule biosynthetic process GO:0010556 225 0.461
Worm Fly
aorta development GO:0035904 4 0.450
aromatic compound biosynthetic process GO:0019438 217 0.447
Worm Fly
specification of organ identity GO:0010092 2 0.438
photoreceptor cell fate commitment GO:0046552 1 0.431
nucleobase containing compound metabolic process GO:0006139 274 0.417
Worm Fly
inner ear receptor cell development GO:0060119 20 0.414
larval development GO:0002164 2 0.394
ear development GO:0043583 127 0.390
neuron differentiation GO:0030182 353 0.385
Zebrafish Fly
cellular macromolecule biosynthetic process GO:0034645 224 0.378
Worm Fly
tube morphogenesis GO:0035239 349 0.374
somitogenesis GO:0001756 87 0.372
neural tube patterning GO:0021532 33 0.371
heterocycle biosynthetic process GO:0018130 215 0.365
Worm Fly
posterior lateral line system development GO:0048915 46 0.361
neuromast mantle cell differentiation GO:0048888 1 0.361
anterior commissure morphogenesis GO:0021960 3 0.359
Fly
positive regulation of stem cell proliferation GO:2000648 1 0.354
neuron fate commitment GO:0048663 26 0.353
Zebrafish
camera type eye morphogenesis GO:0048593 108 0.351
forebrain neuron development GO:0021884 7 0.351
biosynthetic process GO:0009058 294 0.340
Worm Fly
lateral line development GO:0048882 66 0.333
eye development GO:0001654 277 0.325
cellular component morphogenesis GO:0032989 336 0.324
Fly
heart morphogenesis GO:0003007 156 0.318
regulation of rna metabolic process GO:0051252 224 0.315
Worm Fly
pancreas development GO:0031016 84 0.307
posterior lateral line development GO:0048916 38 0.301
sensory system development GO:0048880 76 0.295
regulation of cellular metabolic process GO:0031323 320 0.291
Worm Fly
regulation of rna biosynthetic process GO:2001141 213 0.284
Worm Fly
regulation of multicellular organismal development GO:2000026 223 0.277
photoreceptor cell fate specification GO:0043704 1 0.275
abducens nucleus development GO:0021742 2 0.272
cell proliferation in hindbrain GO:0021534 4 0.267
eye morphogenesis GO:0048592 144 0.264
mesodermal cell fate specification GO:0007501 12 0.260
midbrain development GO:0030901 28 0.259
neuron fate specification GO:0048665 20 0.258
neural tube formation GO:0001841 16 0.257
endocrine system development GO:0035270 65 0.249
cell fate specification GO:0001708 68 0.245
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 68 0.245
rna metabolic process GO:0016070 219 0.244
Worm Fly
regulation of primary metabolic process GO:0080090 311 0.239
Worm Fly
regulation of nitrogen compound metabolic process GO:0051171 251 0.236
Worm Fly
cell differentiation in spinal cord GO:0021515 40 0.228
transcription from rna polymerase ii promoter GO:0006366 80 0.225
Worm Fly
endocardium morphogenesis GO:0003160 4 0.220
digestive system development GO:0055123 289 0.216
ventral spinal cord development GO:0021517 35 0.214
heart development GO:0007507 313 0.212
organic cyclic compound biosynthetic process GO:1901362 223 0.209
Worm Fly
camera type eye development GO:0043010 222 0.208
nitrogen compound metabolic process GO:0006807 319 0.205
Worm Fly
embryonic organ morphogenesis GO:0048562 274 0.204
gene expression GO:0010467 252 0.200
Worm Fly
glomerulus development GO:0032835 27 0.198
regulation of multicellular organismal process GO:0051239 277 0.193
cerebellum development GO:0021549 17 0.188
mesodermal cell differentiation GO:0048333 21 0.188
macromolecule biosynthetic process GO:0009059 227 0.188
Worm Fly
olfactory lobe development GO:0021988 4 0.179
forebrain dorsal ventral pattern formation GO:0021798 1 0.177
anterior posterior pattern specification GO:0009952 152 0.176
regulation of photoreceptor cell differentiation GO:0046532 2 0.175
generation of neurons GO:0048699 385 0.175
Zebrafish Fly
anterior lateral line nerve development GO:0048909 4 0.163
aorta morphogenesis GO:0035909 3 0.162
peripheral nervous system development GO:0007422 55 0.161
neuroblast differentiation GO:0014016 1 0.161
Fly
cerebellum morphogenesis GO:0021587 10 0.160
mechanosensory lateral line system development GO:0048881 49 0.160
regulation of cellular biosynthetic process GO:0031326 245 0.155
Worm Fly
inner ear development GO:0048839 126 0.155
specification of symmetry GO:0009799 204 0.154
blood vessel morphogenesis GO:0048514 216 0.154
central nervous system neuron development GO:0021954 29 0.153
Fly
angiogenesis GO:0001525 158 0.152
thyroid gland development GO:0030878 12 0.150
otolith development GO:0048840 32 0.149
determination of heart left right asymmetry GO:0061371 117 0.149
somatic muscle development GO:0007525 4 0.148
tube formation GO:0035148 25 0.147
ear morphogenesis GO:0042471 64 0.146
organic cyclic compound metabolic process GO:1901360 301 0.145
Worm Fly
somite development GO:0061053 96 0.143
neuromast development GO:0048884 46 0.142
digestive tract development GO:0048565 265 0.141
cellular nitrogen compound metabolic process GO:0034641 290 0.140
Worm Fly
regulation of mechanoreceptor differentiation GO:0045631 1 0.138
membrane fusion GO:0061025 2 0.138
Worm
epithelial cell differentiation GO:0030855 116 0.137
Worm
regulation of nucleic acid templated transcription GO:1903506 213 0.135
Worm Fly
positive regulation of cellular process GO:0048522 201 0.135
Worm Fly
regulation of response to stimulus GO:0048583 269 0.131
metencephalon development GO:0022037 27 0.131
regulation of circadian rhythm GO:0042752 4 0.131
system process GO:0003008 185 0.131
ventral spinal cord interneuron fate commitment GO:0060579 3 0.131
auditory receptor cell fate commitment GO:0009912 4 0.130
stem cell fate commitment GO:0048865 1 0.129
Fly
negative regulation of cellular process GO:0048523 283 0.129
Worm Fly
embryonic organ development GO:0048568 381 0.125
neural retina development GO:0003407 49 0.123
glucose homeostasis GO:0042593 1 0.123
cell fate commitment GO:0045165 99 0.120
positive regulation of rna biosynthetic process GO:1902680 57 0.118
Worm Fly
bmp signaling pathway GO:0030509 52 0.117
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.117
Worm Fly
spinal cord motor neuron differentiation GO:0021522 26 0.115
cellular macromolecule metabolic process GO:0044260 391 0.114
Worm Fly
positive regulation of cell differentiation GO:0045597 30 0.112
maintenance of location GO:0051235 4 0.109
spinal cord association neuron differentiation GO:0021527 1 0.108
cell surface receptor signaling pathway GO:0007166 325 0.106
positive regulation of nucleic acid templated transcription GO:1903508 57 0.106
Worm Fly
apoptotic process involved in development GO:1902742 2 0.103
Zebrafish
cell projection organization GO:0030030 284 0.103
Fly
digestive tract morphogenesis GO:0048546 231 0.101
retina layer formation GO:0010842 24 0.101
primary neural tube formation GO:0014020 1 0.101
regulation of cell communication GO:0010646 232 0.099
positive regulation of nucleobase containing compound metabolic process GO:0045935 69 0.098
Worm Fly
appendage morphogenesis GO:0035107 56 0.098
Fly
lateral line system development GO:0048925 76 0.097
response to glucose GO:0009749 3 0.097
somite specification GO:0001757 12 0.096
oligodendrocyte cell fate specification GO:0021778 4 0.095
pancreatic a cell development GO:0003322 2 0.095
negative regulation of biological process GO:0048519 304 0.094
Worm Fly
negative regulation of transcription dna templated GO:0045892 45 0.092
Worm Fly
neural tube development GO:0021915 62 0.090
fourth ventricle development GO:0021592 8 0.090
cell morphogenesis involved in differentiation GO:0000904 195 0.090
Fly
post embryonic morphogenesis GO:0009886 4 0.089
Fly
spinal cord oligodendrocyte cell fate specification GO:0021530 2 0.089
regulation of retina development in camera type eye GO:1902866 2 0.088
inner ear morphogenesis GO:0042472 63 0.088
positive regulation of transcription dna templated GO:0045893 57 0.088
Worm Fly
anatomical structure arrangement GO:0048532 2 0.087
forebrain anterior posterior pattern specification GO:0021797 3 0.087
segmentation GO:0035282 97 0.086
kidney development GO:0001822 92 0.086
blood vessel development GO:0001568 246 0.084
positive regulation of cell cycle GO:0045787 3 0.084
mesoderm morphogenesis GO:0048332 51 0.083
central nervous system projection neuron axonogenesis GO:0021952 15 0.082
Fly
nephron development GO:0072006 31 0.082
cell proliferation GO:0008283 80 0.082
appendage development GO:0048736 80 0.082
Fly
apoptotic process GO:0006915 116 0.081
Zebrafish
forebrain regionalization GO:0021871 4 0.081
striated muscle tissue development GO:0014706 110 0.081
epidermal cell differentiation GO:0009913 36 0.078
Worm
compound eye development GO:0048749 2 0.076
endocrine pancreas development GO:0031018 27 0.076
heterocycle metabolic process GO:0046483 290 0.075
Worm Fly
vestibular receptor cell differentiation GO:0060114 3 0.074
pronephric glomerulus morphogenesis GO:0035775 6 0.074
embryonic epithelial tube formation GO:0001838 17 0.074
gabaergic neuron differentiation GO:0097154 2 0.073
regulation of stem cell proliferation GO:0072091 2 0.073
peripheral nervous system neuron differentiation GO:0048934 28 0.072
regulation of inner ear receptor cell differentiation GO:2000980 1 0.072
positive regulation of gene expression GO:0010628 71 0.071
Worm Fly
muscle structure development GO:0061061 196 0.071
epithelial tube morphogenesis GO:0060562 148 0.071
neuron neuron synaptic transmission GO:0007270 1 0.071
eye photoreceptor cell differentiation GO:0001754 45 0.069
positive regulation of biosynthetic process GO:0009891 68 0.068
Worm Fly
artery development GO:0060840 22 0.068
photoreceptor cell differentiation GO:0046530 55 0.067
cranial nerve development GO:0021545 42 0.066
cardiocyte differentiation GO:0035051 44 0.064
regulation of neuron differentiation GO:0045664 56 0.064
glial cell differentiation GO:0010001 42 0.062
gastrulation GO:0007369 208 0.062
vestibular receptor cell development GO:0060118 3 0.061
mesoderm development GO:0007498 88 0.061
lipid storage GO:0019915 1 0.059
ventral spinal cord interneuron differentiation GO:0021514 12 0.059
cell proliferation in midbrain GO:0033278 4 0.058
forebrain morphogenesis GO:0048853 6 0.058
forebrain neuron differentiation GO:0021879 14 0.057
regulation of epidermis development GO:0045682 2 0.057
dendrite guidance GO:0070983 0 0.057
glomerulus morphogenesis GO:0072102 7 0.056
motor neuron axon guidance GO:0008045 23 0.055
spinal cord development GO:0021510 46 0.054
nephron morphogenesis GO:0072028 2 0.054
intracellular signal transduction GO:0035556 85 0.054
optic nerve development GO:0021554 15 0.054
regulation of developmental process GO:0050793 247 0.053
epidermal cell fate specification GO:0009957 4 0.053
Worm
auditory receptor cell fate determination GO:0042668 2 0.053
brain morphogenesis GO:0048854 18 0.053
muscle organ development GO:0007517 101 0.053
locus ceruleus development GO:0021703 3 0.053
positive regulation of neuron apoptotic process GO:0043525 1 0.053
blood circulation GO:0008015 87 0.052
behavior GO:0007610 74 0.052
morphogenesis of embryonic epithelium GO:0016331 30 0.052
embryonic camera type eye formation GO:0060900 10 0.051
pronephros development GO:0048793 69 0.051
mesoderm formation GO:0001707 43 0.051
enzyme linked receptor protein signaling pathway GO:0007167 106 0.051
response to hexose GO:0009746 3 0.051
positive regulation of epithelial cell differentiation GO:0030858 2 0.051
cell part morphogenesis GO:0032990 246 0.050
Fly
muscle cell differentiation GO:0042692 139 0.050
epithelial tube formation GO:0072175 19 0.050
muscle fiber development GO:0048747 52 0.050
negative regulation of gene expression GO:0010629 65 0.048
Worm Fly
negative regulation of stem cell differentiation GO:2000737 2 0.048
neural plate development GO:0001840 10 0.048
inner ear receptor cell fate commitment GO:0060120 4 0.047
regulation of neural precursor cell proliferation GO:2000177 3 0.047
olfactory placode development GO:0071698 12 0.046
forebrain cell migration GO:0021885 1 0.046
olfactory bulb development GO:0021772 4 0.046
embryonic limb morphogenesis GO:0030326 2 0.046
striated muscle cell differentiation GO:0051146 129 0.045
tube closure GO:0060606 1 0.045
endocardial cushion development GO:0003197 6 0.044
positive regulation of biological process GO:0048518 253 0.044
Worm Fly
sensory neuron axon guidance GO:0097374 3 0.044
determination of intestine left right asymmetry GO:0071908 2 0.043
type b pancreatic cell development GO:0003323 4 0.043
regulation of endodermal cell fate specification GO:0042663 15 0.042
positive regulation of macromolecule metabolic process GO:0010604 93 0.042
Worm Fly
glial cell fate specification GO:0021780 4 0.042
pons development GO:0021548 11 0.042
apoptotic process involved in morphogenesis GO:0060561 2 0.042
Zebrafish
gliogenesis GO:0042063 45 0.041
dna templated transcription initiation GO:0006352 1 0.041
camera type eye photoreceptor cell differentiation GO:0060219 19 0.041
vasculature development GO:0001944 278 0.041
lateral mesoderm development GO:0048368 23 0.041
cell morphogenesis GO:0000902 289 0.041
Fly
posterior lateral line neuromast development GO:0048919 20 0.040
negative regulation of metabolic process GO:0009892 86 0.040
Worm Fly
morphogenesis of an epithelium GO:0002009 333 0.040
vestibular reflex GO:0060005 2 0.040
glial cell migration GO:0008347 3 0.040
stem cell differentiation GO:0048863 117 0.040
Fly
formation of anatomical boundary GO:0048859 14 0.040
Worm
optic nerve morphogenesis GO:0021631 6 0.039
forebrain neuron fate commitment GO:0021877 1 0.039
response to monosaccharide GO:0034284 3 0.039
atp catabolic process GO:0006200 4 0.038
septum transversum development GO:0003343 4 0.038
heart process GO:0003015 71 0.038
urogenital system development GO:0001655 97 0.038
positive regulation of rna metabolic process GO:0051254 59 0.038
Worm Fly
cellular component movement GO:0006928 335 0.037
Fly
distal tubule development GO:0072017 1 0.037
regulation of cell fate commitment GO:0010453 22 0.037
canonical wnt signaling pathway involved in neural plate anterior posterior pattern formation GO:0060823 4 0.036
axonogenesis GO:0007409 152 0.036
Fly
dendrite morphogenesis GO:0048813 5 0.036
response to chemical GO:0042221 320 0.036
Fly
body morphogenesis GO:0010171 16 0.036
Worm
gastrulation with mouth forming second GO:0001702 44 0.036
nerve development GO:0021675 45 0.036
multicellular organism growth GO:0035264 4 0.035
exocrine pancreas development GO:0031017 28 0.034
response to carbohydrate GO:0009743 3 0.034
central nervous system myelin formation GO:0032289 1 0.034
regulation of neurogenesis GO:0050767 87 0.034
hormone transport GO:0009914 2 0.033
embryonic viscerocranium morphogenesis GO:0048703 52 0.033
auditory receptor cell differentiation GO:0042491 15 0.033
regulation of apoptotic process GO:0042981 98 0.033
diencephalon development GO:0021536 58 0.033
rhombomere 4 development GO:0021570 5 0.033
mammillary body development GO:0021767 4 0.033
polarized epithelial cell differentiation GO:0030859 4 0.033
regulation of organ morphogenesis GO:2000027 35 0.033
reflex GO:0060004 2 0.033
axonal fasciculation GO:0007413 11 0.032
neuron projection development GO:0031175 180 0.032
Fly
cell projection morphogenesis GO:0048858 244 0.032
Fly
signal transduction GO:0007165 455 0.032
nephron epithelium morphogenesis GO:0072088 1 0.032
endocardial cushion formation GO:0003272 2 0.031
dorsal spinal cord development GO:0021516 1 0.031
positive regulation of cellular biosynthetic process GO:0031328 68 0.031
Worm Fly
rhombomere 5 morphogenesis GO:0021664 1 0.031
regulation of neural retina development GO:0061074 2 0.031
central nervous system neuron axonogenesis GO:0021955 18 0.031
Fly
circadian sleep wake cycle GO:0042745 2 0.031
embryonic camera type eye development GO:0031076 29 0.031
regulation of collateral sprouting of intact axon in response to injury GO:0048683 2 0.031
peripheral nervous system neuron development GO:0048935 22 0.031
positive regulation of developmental process GO:0051094 50 0.031
negative regulation of cellular macromolecule biosynthetic process GO:2000113 48 0.031
Worm Fly
negative regulation of nucleobase containing compound metabolic process GO:0045934 59 0.031
Worm Fly
embryonic heart tube formation GO:0003144 1 0.030
rhombomere development GO:0021546 19 0.030
adult behavior GO:0030534 2 0.030
ventricular cardiac muscle tissue morphogenesis GO:0055010 2 0.030
neuron recognition GO:0008038 18 0.030
ventral spinal cord interneuron specification GO:0021521 3 0.030
positive regulation of macromolecule biosynthetic process GO:0010557 59 0.030
Worm Fly
multicellular organism reproduction GO:0032504 35 0.030
ectodermal placode development GO:0071696 37 0.030
circulatory system process GO:0003013 87 0.029
regulation of blood pressure GO:0008217 1 0.029
spinal cord motor neuron cell fate specification GO:0021520 8 0.029
chemotaxis GO:0006935 104 0.029
Fly
regulation of multicellular organism growth GO:0040014 4 0.029
optic cup morphogenesis involved in camera type eye development GO:0002072 7 0.029
carbohydrate homeostasis GO:0033500 1 0.028
negative regulation of nitrogen compound metabolic process GO:0051172 59 0.028
Worm Fly
response to hydrogen peroxide GO:0042542 3 0.028
proepicardium development GO:0003342 4 0.028
organ formation GO:0048645 17 0.028
retinal cone cell differentiation GO:0042670 12 0.028
positive regulation of notch signaling pathway GO:0045747 3 0.028
defense response to other organism GO:0098542 33 0.028
Fly
defense response GO:0006952 47 0.028
Fly
organic substance catabolic process GO:1901575 28 0.027
nephron tubule morphogenesis GO:0072078 1 0.027
neuron development GO:0048666 262 0.027
Fly
endocardium formation GO:0060214 1 0.026
cellular response to retinoic acid GO:0071300 1 0.026
cilium or flagellum dependent cell motility GO:0001539 4 0.026
negative regulation of rna biosynthetic process GO:1902679 45 0.026
Worm Fly
regulation of organ growth GO:0046620 3 0.026
endodermal cell fate determination GO:0007493 2 0.026
growth GO:0040007 174 0.026
cardiogenic plate morphogenesis GO:0003142 1 0.026
positive regulation of nervous system development GO:0051962 25 0.026
heart looping GO:0001947 94 0.026
regulation of reproductive process GO:2000241 4 0.026
negative regulation of macromolecule metabolic process GO:0010605 76 0.025
Worm Fly
heart contraction GO:0060047 71 0.025
programmed cell death GO:0012501 119 0.025
Zebrafish
determination of bilateral symmetry GO:0009855 204 0.025
neuromast hair cell differentiation GO:0048886 12 0.025
negative regulation of multicellular organismal process GO:0051241 69 0.025
cell fate specification involved in pattern specification GO:0060573 3 0.025
locomotory behavior GO:0007626 34 0.025
telencephalon development GO:0021537 14 0.025
Fly
pancreatic d cell development GO:0003324 1 0.025
myeloid cell differentiation GO:0030099 86 0.024
embryonic appendage morphogenesis GO:0035113 30 0.024
response to abiotic stimulus GO:0009628 122 0.024
fin development GO:0033333 77 0.023
single organism organelle organization GO:1902589 199 0.023
aging GO:0007568 2 0.023
enteroendocrine cell differentiation GO:0035883 9 0.023
nucleocytoplasmic transport GO:0006913 4 0.023
hemopoiesis GO:0030097 183 0.023
ribonucleoside monophosphate catabolic process GO:0009158 4 0.023
posterior lateral line nerve development GO:0048918 8 0.023
negative regulation of cysteine type endopeptidase activity GO:2000117 8 0.022
positive regulation of cell division GO:0051781 2 0.022
cellular response to external stimulus GO:0071496 2 0.022
taste bud formation GO:0061195 3 0.022
ameboidal type cell migration GO:0001667 143 0.022
phagocytosis GO:0006909 3 0.022
regulation of biological quality GO:0065008 263 0.022
cell differentiation in hindbrain GO:0021533 5 0.022
artery morphogenesis GO:0048844 14 0.022
cellular amino acid biosynthetic process GO:0008652 2 0.021
retinal pigment epithelium development GO:0003406 8 0.021
cell cycle GO:0007049 93 0.021
negative regulation of cellular metabolic process GO:0031324 77 0.021
Worm Fly
protein import into nucleus GO:0006606 3 0.021
embryonic skeletal system development GO:0048706 97 0.021
response to inorganic substance GO:0010035 38 0.021
hypothalamus development GO:0021854 14 0.021
floor plate development GO:0033504 15 0.021
epithelial cell differentiation involved in kidney development GO:0035850 13 0.021
cell motility GO:0048870 244 0.021
cell division GO:0051301 20 0.021
negative regulation of biosynthetic process GO:0009890 55 0.021
Worm Fly
ventral midline development GO:0007418 13 0.020
Fly
cranial nerve morphogenesis GO:0021602 15 0.020
muscle cell development GO:0055001 115 0.020
positive regulation of neuron death GO:1901216 1 0.020
embryonic pattern specification GO:0009880 44 0.020
nephric duct development GO:0072176 13 0.020
positive regulation of neural precursor cell proliferation GO:2000179 1 0.020
negative regulation of reproductive process GO:2000242 3 0.020
negative regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043154 7 0.020
response to stress GO:0006950 263 0.020
Fly
cerebellar cortex development GO:0021695 5 0.020
reactive oxygen species metabolic process GO:0072593 6 0.020
embryonic heart tube morphogenesis GO:0003143 108 0.020
embryonic cranial skeleton morphogenesis GO:0048701 90 0.020
mediolateral intercalation GO:0060031 3 0.020
positive regulation of cellular metabolic process GO:0031325 94 0.020
Worm Fly
peptide transport GO:0015833 1 0.020
kidney rudiment formation GO:0072003 3 0.019
retina development in camera type eye GO:0060041 146 0.019
determination of left right symmetry GO:0007368 179 0.019
regulation of catalytic activity GO:0050790 55 0.019
auditory receptor cell development GO:0060117 8 0.019
embryonic eye morphogenesis GO:0048048 30 0.019
cardiac cell fate commitment GO:0060911 1 0.019
embryonic hemopoiesis GO:0035162 53 0.019
cellular component assembly involved in morphogenesis GO:0010927 107 0.019
striated muscle cell development GO:0055002 108 0.019
mesenchyme development GO:0060485 127 0.018
embryonic heart tube development GO:0035050 133 0.018
pigmentation GO:0043473 85 0.018
rhombomere 4 morphogenesis GO:0021661 5 0.018
mesodermal cell fate commitment GO:0001710 14 0.018
type b pancreatic cell differentiation GO:0003309 8 0.018
female sex differentiation GO:0046660 4 0.018
organelle assembly GO:0070925 110 0.018
homeostatic process GO:0042592 142 0.018
embryonic pectoral fin morphogenesis GO:0035118 24 0.018
establishment of localization GO:0051234 244 0.018
kidney epithelium development GO:0072073 23 0.017
neuroblast proliferation GO:0007405 2 0.017
negative regulation of cellular catabolic process GO:0031330 3 0.017
cell migration GO:0016477 237 0.017
regulation of cardiac muscle tissue development GO:0055024 1 0.017
response to oxygen containing compound GO:1901700 55 0.017
carboxylic acid catabolic process GO:0046395 3 0.017
inositol lipid mediated signaling GO:0048017 2 0.017
axon development GO:0061564 166 0.017
Fly
negative regulation of protein phosphorylation GO:0001933 4 0.017
response to organic substance GO:0010033 153 0.017
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 20 0.017
g1 s transition of mitotic cell cycle GO:0000082 1 0.017
multicellular organismal reproductive process GO:0048609 35 0.016
regulation of cell cycle GO:0051726 52 0.016
cell fate determination GO:0001709 7 0.016
Fly
intracellular receptor signaling pathway GO:0030522 30 0.016
formation of primary germ layer GO:0001704 62 0.016
regulation of hormone secretion GO:0046883 2 0.016
positive regulation of neuron differentiation GO:0045666 12 0.016

eng2b disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.305
nervous system disease DOID:863 0 0.034
cardiovascular system disease DOID:1287 0 0.022
urinary system disease DOID:18 0 0.021
musculoskeletal system disease DOID:17 0 0.020
sensory system disease DOID:0050155 0 0.019
eye and adnexa disease DOID:1492 0 0.019
eye disease DOID:5614 0 0.019
reproductive system disease DOID:15 0 0.019