|
|
response to alkaloid
|
GO:0043279 |
2 |
0.824
|
|
|
|
heart development
|
GO:0007507 |
313 |
0.794
|
|
|
|
positive regulation of transport
|
GO:0051050 |
2 |
0.785
|
|
|
|
regulation of cellular metabolic process
|
GO:0031323 |
320 |
0.728
|
Human Zebrafish Mouse Rat Worm Fly |
|
|
neuron neuron synaptic transmission
|
GO:0007270 |
1 |
0.643
|
|
|
|
cellular nitrogen compound biosynthetic process
|
GO:0044271 |
218 |
0.621
|
Human Zebrafish Mouse Rat Worm Fly |
|
|
regulation of blood vessel size
|
GO:0050880 |
2 |
0.596
|
|
|
|
cellular nitrogen compound metabolic process
|
GO:0034641 |
290 |
0.578
|
Human Zebrafish Mouse Rat Worm Fly |
|
|
response to organic cyclic compound
|
GO:0014070 |
51 |
0.575
|
|
|
|
extrinsic apoptotic signaling pathway
|
GO:0097191 |
3 |
0.572
|
|
|
|
central nervous system development
|
GO:0007417 |
387 |
0.570
|
Zebrafish |
|
|
smooth muscle contraction
|
GO:0006939 |
2 |
0.536
|
|
|
|
regulation of transcription dna templated
|
GO:0006355 |
213 |
0.534
|
Human Zebrafish Mouse Rat Worm Fly |
|
|
positive regulation of cytokine production
|
GO:0001819 |
2 |
0.528
|
|
|
|
response to stress
|
GO:0006950 |
263 |
0.525
|
|
|
|
heterocycle metabolic process
|
GO:0046483 |
290 |
0.511
|
Human Zebrafish Mouse Rat Worm Fly |
|
|
regulation of neural precursor cell proliferation
|
GO:2000177 |
3 |
0.497
|
|
|
|
embryo development ending in birth or egg hatching
|
GO:0009792 |
271 |
0.484
|
Mouse |
|
|
heterocycle biosynthetic process
|
GO:0018130 |
215 |
0.471
|
Human Zebrafish Mouse Rat Worm Fly |
|
|
transport
|
GO:0006810 |
220 |
0.462
|
|
|
|
response to radiation
|
GO:0009314 |
51 |
0.458
|
|
|
|
nucleic acid metabolic process
|
GO:0090304 |
244 |
0.454
|
Human Zebrafish Mouse Rat Worm Fly |
|
|
regulation of transcription from rna polymerase ii promoter in response to oxidative stress
|
GO:0043619 |
0 |
0.444
|
Mouse |
|
|
response to abiotic stimulus
|
GO:0009628 |
122 |
0.434
|
|
|
|
sodium ion transport
|
GO:0006814 |
24 |
0.431
|
|
|
|
cellular response to hormone stimulus
|
GO:0032870 |
39 |
0.411
|
Fly |
|
|
single organism metabolic process
|
GO:0044710 |
217 |
0.409
|
|
|
|
regulation of cellular carbohydrate metabolic process
|
GO:0010675 |
4 |
0.402
|
|
|
|
small molecule metabolic process
|
GO:0044281 |
77 |
0.402
|
|
|
|
metal ion homeostasis
|
GO:0055065 |
26 |
0.397
|
Mouse |
|
|
ion homeostasis
|
GO:0050801 |
41 |
0.394
|
Mouse |
|
|
regulation of nucleic acid templated transcription
|
GO:1903506 |
213 |
0.393
|
Human Zebrafish Mouse Rat Worm Fly |
|
|
monovalent inorganic cation transport
|
GO:0015672 |
42 |
0.379
|
|
|
|
regulation of epithelial cell proliferation
|
GO:0050678 |
3 |
0.371
|
|
|
|
brain development
|
GO:0007420 |
293 |
0.371
|
Zebrafish |
|
|
organic cyclic compound metabolic process
|
GO:1901360 |
301 |
0.367
|
Human Zebrafish Mouse Rat Worm Fly |
|
|
positive regulation of programmed cell death
|
GO:0043068 |
29 |
0.358
|
|
|
|
response to organic substance
|
GO:0010033 |
153 |
0.357
|
Zebrafish Fly |
|
|
system process
|
GO:0003008 |
185 |
0.343
|
Mouse |
|
|
regulation of metabolic process
|
GO:0019222 |
359 |
0.340
|
Human Zebrafish Mouse Rat Worm Fly |
|
|
positive regulation of biological process
|
GO:0048518 |
253 |
0.339
|
Human Mouse Rat Fly |
|
|
regulation of nitrogen compound metabolic process
|
GO:0051171 |
251 |
0.333
|
Human Zebrafish Mouse Rat Worm Fly |
|
|
homeostatic process
|
GO:0042592 |
142 |
0.333
|
Mouse |
|
|
response to external stimulus
|
GO:0009605 |
264 |
0.332
|
Zebrafish Worm |
|
|
vasculature development
|
GO:0001944 |
278 |
0.332
|
Mouse |
|
|
regulation of dna templated transcription in response to stress
|
GO:0043620 |
0 |
0.331
|
Mouse |
|
|
inorganic cation transmembrane transport
|
GO:0098662 |
50 |
0.331
|
|
|
|
negative regulation of biological process
|
GO:0048519 |
304 |
0.323
|
Worm Fly |
|
|
eye development
|
GO:0001654 |
277 |
0.322
|
|
|
|
response to steroid hormone
|
GO:0048545 |
35 |
0.320
|
|
|
|
regulation of biosynthetic process
|
GO:0009889 |
250 |
0.318
|
Human Zebrafish Mouse Rat Worm Fly |
|
|
nitrogen compound metabolic process
|
GO:0006807 |
319 |
0.314
|
Human Zebrafish Mouse Rat Worm Fly |
|
|
cation homeostasis
|
GO:0055080 |
33 |
0.310
|
Mouse |
|
|
cation transport
|
GO:0006812 |
81 |
0.308
|
|
|
|
response to glucocorticoid
|
GO:0051384 |
1 |
0.305
|
|
|
|
rna biosynthetic process
|
GO:0032774 |
181 |
0.299
|
Human Zebrafish Mouse Rat Worm Fly |
|
|
response to chemical
|
GO:0042221 |
320 |
0.298
|
Human Zebrafish Mouse Fly |
|
|
determination of left right symmetry
|
GO:0007368 |
179 |
0.295
|
|
|
|
response to oxygen levels
|
GO:0070482 |
25 |
0.295
|
|
|
|
regulation of multicellular organismal development
|
GO:2000026 |
223 |
0.290
|
|
|
|
cellular response to organic cyclic compound
|
GO:0071407 |
38 |
0.290
|
|
|
|
organic substance biosynthetic process
|
GO:1901576 |
289 |
0.287
|
Human Zebrafish Mouse Rat Worm Fly |
|
|
cellular aromatic compound metabolic process
|
GO:0006725 |
295 |
0.284
|
Human Zebrafish Mouse Rat Worm Fly |
|
|
regulation of transport
|
GO:0051049 |
45 |
0.282
|
|
|
|
regulation of response to stimulus
|
GO:0048583 |
269 |
0.276
|
|
|
|
regulation of anatomical structure size
|
GO:0090066 |
33 |
0.273
|
|
|
|
response to light stimulus
|
GO:0009416 |
46 |
0.273
|
|
|
|
nucleic acid templated transcription
|
GO:0097659 |
181 |
0.271
|
Human Zebrafish Mouse Rat Worm Fly |
|
|
tube morphogenesis
|
GO:0035239 |
349 |
0.269
|
|
|
|
nucleobase containing compound metabolic process
|
GO:0006139 |
274 |
0.266
|
Human Zebrafish Mouse Rat Worm Fly |
|
|
neuron development
|
GO:0048666 |
262 |
0.264
|
Zebrafish |
|
|
blood circulation
|
GO:0008015 |
87 |
0.263
|
Mouse |
|
|
response to transition metal nanoparticle
|
GO:1990267 |
28 |
0.262
|
|
|
|
neurological system process
|
GO:0050877 |
62 |
0.262
|
Mouse |
|
|
response to temperature stimulus
|
GO:0009266 |
15 |
0.261
|
Worm |
|
|
rna metabolic process
|
GO:0016070 |
219 |
0.260
|
Human Zebrafish Mouse Rat Worm Fly |
|
|
cellular carbohydrate metabolic process
|
GO:0044262 |
4 |
0.259
|
|
|
|
regulation of cellular biosynthetic process
|
GO:0031326 |
245 |
0.255
|
Human Zebrafish Mouse Rat Worm Fly |
|
|
chemical homeostasis
|
GO:0048878 |
49 |
0.252
|
Mouse |
|
|
morphogenesis of an epithelium
|
GO:0002009 |
333 |
0.248
|
|
|
|
gene expression
|
GO:0010467 |
252 |
0.244
|
Human Zebrafish Mouse Rat Worm Fly |
|
|
response to corticosteroid
|
GO:0031960 |
1 |
0.243
|
|
|
|
positive regulation of map kinase activity
|
GO:0043406 |
3 |
0.242
|
|
|
|
heart morphogenesis
|
GO:0003007 |
156 |
0.237
|
|
|
|
blood vessel development
|
GO:0001568 |
246 |
0.236
|
Mouse |
|
|
single organism transport
|
GO:0044765 |
206 |
0.232
|
|
|
|
regulation of synaptic plasticity
|
GO:0048167 |
1 |
0.231
|
|
|
|
locomotion
|
GO:0040011 |
313 |
0.231
|
Zebrafish Fly |
|
|
regulation of nucleobase containing compound metabolic process
|
GO:0019219 |
250 |
0.231
|
Human Zebrafish Mouse Rat Worm Fly |
|
|
ion transport
|
GO:0006811 |
114 |
0.230
|
|
|
|
regulation of cell differentiation
|
GO:0045595 |
142 |
0.227
|
|
|
|
positive regulation of apoptotic process
|
GO:0043065 |
29 |
0.224
|
|
|
|
regulation of rna biosynthetic process
|
GO:2001141 |
213 |
0.223
|
Human Zebrafish Mouse Rat Worm Fly |
|
|
cellular ion homeostasis
|
GO:0006873 |
17 |
0.216
|
|
|
|
regulation of reactive oxygen species metabolic process
|
GO:2000377 |
2 |
0.215
|
|
|
|
regulation of protein transport
|
GO:0051223 |
3 |
0.215
|
|
|
|
vascular process in circulatory system
|
GO:0003018 |
6 |
0.213
|
|
|
|
regulation of biological quality
|
GO:0065008 |
263 |
0.210
|
Mouse |
|
|
determination of bilateral symmetry
|
GO:0009855 |
204 |
0.209
|
|
|
|
positive regulation of nitrogen compound metabolic process
|
GO:0051173 |
69 |
0.207
|
Human Mouse Rat Fly |
|
|
positive regulation of immune system process
|
GO:0002684 |
17 |
0.204
|
|
|
|
regulation of establishment of protein localization
|
GO:0070201 |
4 |
0.203
|
|
|
|
regulation of primary metabolic process
|
GO:0080090 |
311 |
0.202
|
Human Zebrafish Mouse Rat Worm Fly |
|
|
cation transmembrane transport
|
GO:0098655 |
65 |
0.202
|
|
|
|
regulation of tube size
|
GO:0035150 |
2 |
0.201
|
|
|
|
nucleobase containing compound biosynthetic process
|
GO:0034654 |
205 |
0.198
|
Human Zebrafish Mouse Rat Worm Fly |
|
|
cellular biosynthetic process
|
GO:0044249 |
286 |
0.198
|
Human Zebrafish Mouse Rat Worm Fly |
|
|
regulation of membrane potential
|
GO:0042391 |
23 |
0.197
|
|
|
|
cellular response to organic substance
|
GO:0071310 |
105 |
0.188
|
Fly |
|
|
nitric oxide metabolic process
|
GO:0046209 |
2 |
0.187
|
|
|
|
cell proliferation
|
GO:0008283 |
80 |
0.185
|
|
|
|
metal ion transport
|
GO:0030001 |
58 |
0.183
|
|
|
|
response to hormone
|
GO:0009725 |
48 |
0.182
|
Fly |
|
|
regulation of carbohydrate metabolic process
|
GO:0006109 |
4 |
0.182
|
|
|
|
ion transmembrane transport
|
GO:0034220 |
91 |
0.181
|
|
|
|
transcription dna templated
|
GO:0006351 |
181 |
0.181
|
Human Zebrafish Mouse Rat Worm Fly |
|
|
regulation of defense response
|
GO:0031347 |
14 |
0.181
|
|
|
|
embryonic heart tube morphogenesis
|
GO:0003143 |
108 |
0.179
|
|
|
|
regulation of endothelial cell proliferation
|
GO:0001936 |
1 |
0.179
|
|
|
|
response to oxygen containing compound
|
GO:1901700 |
55 |
0.176
|
Zebrafish Fly |
|
|
cell migration
|
GO:0016477 |
237 |
0.176
|
Fly |
|
|
positive regulation of cell death
|
GO:0010942 |
29 |
0.175
|
|
|
|
muscle structure development
|
GO:0061061 |
196 |
0.174
|
Mouse |
|
|
embryonic organ development
|
GO:0048568 |
381 |
0.174
|
Mouse |
|
|
regulation of molecular function
|
GO:0065009 |
70 |
0.173
|
|
|
|
regulation of localization
|
GO:0032879 |
104 |
0.173
|
Fly |
|
|
cellular component morphogenesis
|
GO:0032989 |
336 |
0.173
|
Zebrafish |
|
|
cellular response to endogenous stimulus
|
GO:0071495 |
68 |
0.172
|
Fly |
|
|
regulation of signaling
|
GO:0023051 |
235 |
0.172
|
|
|
|
reactive oxygen species biosynthetic process
|
GO:1903409 |
1 |
0.170
|
|
|
|
localization of cell
|
GO:0051674 |
244 |
0.167
|
Fly |
|
|
aging
|
GO:0007568 |
2 |
0.166
|
Worm |
|
|
sodium ion transmembrane transport
|
GO:0035725 |
21 |
0.165
|
|
|
|
establishment of localization
|
GO:0051234 |
244 |
0.161
|
|
|
|
regulation of cell communication
|
GO:0010646 |
232 |
0.156
|
|
|
|
sensory perception
|
GO:0007600 |
39 |
0.156
|
Mouse |
|
|
positive regulation of cell motility
|
GO:2000147 |
11 |
0.153
|
|
|
|
embryonic organ morphogenesis
|
GO:0048562 |
274 |
0.153
|
|
|
|
g protein coupled receptor signaling pathway
|
GO:0007186 |
74 |
0.153
|
|
|
|
regulation of inflammatory response
|
GO:0050727 |
2 |
0.153
|
|
|
|
organelle organization
|
GO:0006996 |
227 |
0.149
|
Mouse |
|
|
response to drug
|
GO:0042493 |
3 |
0.147
|
|
|
|
oxidation reduction process
|
GO:0055114 |
41 |
0.146
|
|
|
|
erythrocyte homeostasis
|
GO:0034101 |
55 |
0.146
|
Mouse |
|
|
oxoacid metabolic process
|
GO:0043436 |
31 |
0.145
|
|
|
|
regulation of autophagy
|
GO:0010506 |
3 |
0.144
|
Fly |
|
|
hematopoietic or lymphoid organ development
|
GO:0048534 |
191 |
0.143
|
Mouse |
|
|
biosynthetic process
|
GO:0009058 |
294 |
0.143
|
Human Zebrafish Mouse Rat Worm Fly |
|
|
response to salt stress
|
GO:0009651 |
10 |
0.143
|
|
|
|
larval development
|
GO:0002164 |
2 |
0.141
|
|
|
|
positive regulation of response to external stimulus
|
GO:0032103 |
9 |
0.141
|
|
|
|
cell motility
|
GO:0048870 |
244 |
0.141
|
Fly |
|
|
regulation of system process
|
GO:0044057 |
40 |
0.141
|
Mouse |
|
|
regulation of gene expression
|
GO:0010468 |
265 |
0.139
|
Human Zebrafish Mouse Rat Worm Fly |
|
|
digestive system development
|
GO:0055123 |
289 |
0.139
|
|
|
|
single organism localization
|
GO:1902578 |
225 |
0.138
|
|
|
|
transmembrane transport
|
GO:0055085 |
120 |
0.136
|
|
|
|
regulation of developmental process
|
GO:0050793 |
247 |
0.135
|
|
|
|
regulation of blood circulation
|
GO:1903522 |
32 |
0.134
|
Mouse |
|
|
cellular response to oxygen levels
|
GO:0071453 |
1 |
0.132
|
Human Fly |
|
|
response to metal ion
|
GO:0010038 |
34 |
0.132
|
|
|
|
regulation of apoptotic process
|
GO:0042981 |
98 |
0.132
|
|
|
|
positive regulation of cellular process
|
GO:0048522 |
201 |
0.131
|
Human Mouse Rat Fly |
|
|
protein secretion
|
GO:0009306 |
1 |
0.131
|
|
|
|
positive regulation of protein kinase b signaling
|
GO:0051897 |
1 |
0.131
|
|
|
|
carboxylic acid metabolic process
|
GO:0019752 |
22 |
0.130
|
|
|
|
cellular response to external stimulus
|
GO:0071496 |
2 |
0.129
|
Worm |
|
|
regulation of blood pressure
|
GO:0008217 |
1 |
0.128
|
|
|
|
taxis
|
GO:0042330 |
109 |
0.125
|
Zebrafish |
|
|
action potential
|
GO:0001508 |
19 |
0.125
|
|
|
|
lipid storage
|
GO:0019915 |
1 |
0.124
|
|
|
|
positive regulation of immune effector process
|
GO:0002699 |
3 |
0.123
|
|
|
|
organic acid metabolic process
|
GO:0006082 |
31 |
0.123
|
|
|
|
organic cyclic compound biosynthetic process
|
GO:1901362 |
223 |
0.123
|
Human Zebrafish Mouse Rat Worm Fly |
|
|
cellular macromolecule metabolic process
|
GO:0044260 |
391 |
0.121
|
Human Zebrafish Mouse Rat Worm Fly |
|
|
cellular response to peptide hormone stimulus
|
GO:0071375 |
5 |
0.120
|
Fly |
|
|
positive regulation of epithelial cell proliferation
|
GO:0050679 |
1 |
0.119
|
|
|
|
heart looping
|
GO:0001947 |
94 |
0.117
|
|
|
|
regulation of sodium ion transport
|
GO:0002028 |
2 |
0.116
|
|
|
|
negative regulation of developmental process
|
GO:0051093 |
65 |
0.116
|
|
|
|
defense response
|
GO:0006952 |
47 |
0.116
|
|
|
|
cellular macromolecule biosynthetic process
|
GO:0034645 |
224 |
0.113
|
Human Zebrafish Mouse Rat Worm Fly |
|
|
generation of neurons
|
GO:0048699 |
385 |
0.112
|
|
|
|
cellular response to lipopolysaccharide
|
GO:0071222 |
3 |
0.111
|
|
|
|
actin filament based process
|
GO:0030029 |
64 |
0.111
|
|
|
|
cellular protein modification process
|
GO:0006464 |
100 |
0.110
|
|
|
|
camera type eye development
|
GO:0043010 |
222 |
0.110
|
|
|
|
cellular amine metabolic process
|
GO:0044106 |
2 |
0.110
|
|
|
|
neural crest cell differentiation
|
GO:0014033 |
72 |
0.109
|
|
|
|
positive regulation of epithelial cell migration
|
GO:0010634 |
2 |
0.109
|
|
|
|
cognition
|
GO:0050890 |
1 |
0.108
|
|
|
|
neuron projection development
|
GO:0031175 |
180 |
0.108
|
Zebrafish |
|
|
regulation of stem cell proliferation
|
GO:0072091 |
2 |
0.108
|
|
|
|
reactive oxygen species metabolic process
|
GO:0072593 |
6 |
0.108
|
|
|
|
response to nitrogen compound
|
GO:1901698 |
19 |
0.107
|
Fly |
|
|
stem cell proliferation
|
GO:0072089 |
4 |
0.107
|
|
|
|
regulation of immune response
|
GO:0050776 |
14 |
0.105
|
|
|
|
regulation of cell death
|
GO:0010941 |
103 |
0.105
|
|
|
|
muscle cell differentiation
|
GO:0042692 |
139 |
0.105
|
Mouse |
|
|
synaptic transmission
|
GO:0007268 |
35 |
0.104
|
|
|
|
multicellular organismal macromolecule metabolic process
|
GO:0044259 |
2 |
0.103
|
|
|
|
cell projection morphogenesis
|
GO:0048858 |
244 |
0.102
|
Zebrafish |
|
|
negative regulation of cytoplasmic transport
|
GO:1903650 |
2 |
0.102
|
|
|
|
immune response regulating signaling pathway
|
GO:0002764 |
5 |
0.102
|
|
|
|
regulation of immune system process
|
GO:0002682 |
34 |
0.102
|
|
|
|
lipid metabolic process
|
GO:0006629 |
52 |
0.102
|
|
|
|
mesenchymal cell differentiation
|
GO:0048762 |
87 |
0.102
|
|
|
|
chordate embryonic development
|
GO:0043009 |
271 |
0.101
|
Mouse |
|
|
behavior
|
GO:0007610 |
74 |
0.100
|
|
|
|
cellular chemical homeostasis
|
GO:0055082 |
17 |
0.099
|
|
|
|
positive regulation of cellular biosynthetic process
|
GO:0031328 |
68 |
0.099
|
Human Mouse Rat Fly |
|
|
positive regulation of defense response
|
GO:0031349 |
9 |
0.099
|
|
|
|
tissue migration
|
GO:0090130 |
37 |
0.099
|
|
|
|
embryonic heart tube development
|
GO:0035050 |
133 |
0.099
|
|
|
|
negative regulation of response to stimulus
|
GO:0048585 |
104 |
0.099
|
|
|
|
ameboidal type cell migration
|
GO:0001667 |
143 |
0.098
|
|
|
|
estrogen metabolic process
|
GO:0008210 |
2 |
0.098
|
|
|
|
regulation of cytokine production
|
GO:0001817 |
3 |
0.097
|
|
|
|
energy reserve metabolic process
|
GO:0006112 |
2 |
0.096
|
|
|
|
negative regulation of protein transport
|
GO:0051224 |
3 |
0.095
|
|
|
|
aromatic compound biosynthetic process
|
GO:0019438 |
217 |
0.094
|
Human Zebrafish Mouse Rat Worm Fly |
|
|
cellular amino acid metabolic process
|
GO:0006520 |
7 |
0.093
|
|
|
|
response to inorganic substance
|
GO:0010035 |
38 |
0.093
|
|
|
|
transmembrane receptor protein tyrosine kinase signaling pathway
|
GO:0007169 |
42 |
0.093
|
|
|
|
embryonic hemopoiesis
|
GO:0035162 |
53 |
0.092
|
|
|
|
cell death
|
GO:0008219 |
121 |
0.092
|
|
|
|
iron ion homeostasis
|
GO:0055072 |
4 |
0.091
|
Mouse |
|
|
negative regulation of metabolic process
|
GO:0009892 |
86 |
0.091
|
|
|
|
hemopoiesis
|
GO:0030097 |
183 |
0.091
|
Mouse |
|
|
regionalization
|
GO:0003002 |
274 |
0.091
|
|
|
|
head development
|
GO:0060322 |
303 |
0.091
|
Zebrafish |
|
|
regulation of muscle contraction
|
GO:0006937 |
3 |
0.090
|
|
|
|
regulation of macromolecule biosynthetic process
|
GO:0010556 |
225 |
0.089
|
Human Zebrafish Mouse Rat Worm Fly |
|
|
single organism biosynthetic process
|
GO:0044711 |
71 |
0.089
|
|
|
|
regulation of transcription from rna polymerase ii promoter in response to stress
|
GO:0043618 |
0 |
0.089
|
Mouse |
|
|
regulation of response to oxidative stress
|
GO:1902882 |
2 |
0.089
|
|
|
|
determination of heart left right asymmetry
|
GO:0061371 |
117 |
0.088
|
|
|
|
regulation of intracellular protein transport
|
GO:0033157 |
3 |
0.088
|
|
|
|
response to uv
|
GO:0009411 |
3 |
0.088
|
|
|
|
transcription from rna polymerase ii promoter
|
GO:0006366 |
80 |
0.088
|
Human Mouse Rat Worm Fly |
|
|
positive regulation of secretion by cell
|
GO:1903532 |
1 |
0.088
|
|
|
|
response to nutrient
|
GO:0007584 |
3 |
0.088
|
|
|
|
cellular cation homeostasis
|
GO:0030003 |
17 |
0.087
|
|
|
|
cell surface receptor signaling pathway
|
GO:0007166 |
325 |
0.087
|
|
|
|
peptidyl serine phosphorylation
|
GO:0018105 |
1 |
0.087
|
|
|
|
positive regulation of protein metabolic process
|
GO:0051247 |
23 |
0.087
|
|
|
|
activation of immune response
|
GO:0002253 |
9 |
0.086
|
|
|
|
response to endogenous stimulus
|
GO:0009719 |
83 |
0.086
|
Fly |
|
|
response to lipid
|
GO:0033993 |
60 |
0.084
|
|
|
|
positive regulation of cellular metabolic process
|
GO:0031325 |
94 |
0.082
|
Human Mouse Rat Fly |
|
|
regulation of macromolecule metabolic process
|
GO:0060255 |
317 |
0.082
|
Human Zebrafish Mouse Rat Worm Fly |
|
|
regulation of cell proliferation
|
GO:0042127 |
37 |
0.082
|
|
|
|
actin cytoskeleton organization
|
GO:0030036 |
63 |
0.082
|
|
|
|
regulation of cell activation
|
GO:0050865 |
1 |
0.082
|
|
|
|
connective tissue development
|
GO:0061448 |
99 |
0.081
|
|
|
|
regulation of cell migration involved in sprouting angiogenesis
|
GO:0090049 |
3 |
0.081
|
|
|
|
myeloid cell differentiation
|
GO:0030099 |
86 |
0.081
|
Mouse |
|
|
response to bacterium
|
GO:0009617 |
58 |
0.079
|
|
|
|
response to osmotic stress
|
GO:0006970 |
11 |
0.078
|
|
|
|
specification of symmetry
|
GO:0009799 |
204 |
0.077
|
|
|
|
positive regulation of cellular component movement
|
GO:0051272 |
11 |
0.077
|
|
|
|
response to molecule of bacterial origin
|
GO:0002237 |
14 |
0.077
|
|
|
|
cellular response to oxygen containing compound
|
GO:1901701 |
20 |
0.076
|
Fly |
|
|
cellular response to chemical stimulus
|
GO:0070887 |
157 |
0.076
|
Human Mouse Fly |
|
|
cellular response to nitrogen compound
|
GO:1901699 |
6 |
0.076
|
Fly |
|
|
hydrogen peroxide metabolic process
|
GO:0042743 |
2 |
0.075
|
|
|
|
regulation of locomotion
|
GO:0040012 |
55 |
0.074
|
Fly |
|
|
innate immune response activating signal transduction
|
GO:0002758 |
5 |
0.071
|
|
|
|
inorganic ion transmembrane transport
|
GO:0098660 |
57 |
0.071
|
|
|
|
inositol lipid mediated signaling
|
GO:0048017 |
2 |
0.071
|
|
|
|
cellular response to decreased oxygen levels
|
GO:0036294 |
1 |
0.071
|
Human Fly |
|
|
regulation of protein import into nucleus
|
GO:0042306 |
2 |
0.071
|
|
|
|
organophosphate biosynthetic process
|
GO:0090407 |
23 |
0.070
|
|
|
|
response to mechanical stimulus
|
GO:0009612 |
24 |
0.070
|
|
|
|
positive regulation of blood circulation
|
GO:1903524 |
2 |
0.070
|
|
|
|
positive regulation of neuron death
|
GO:1901216 |
1 |
0.069
|
|
|
|
endocrine process
|
GO:0050886 |
2 |
0.069
|
|
|
|
cell projection organization
|
GO:0030030 |
284 |
0.067
|
Zebrafish |
|
|
positive regulation of cellular protein metabolic process
|
GO:0032270 |
22 |
0.067
|
|
|
|
epithelial cell differentiation
|
GO:0030855 |
116 |
0.066
|
|
|
|
negative regulation of cell death
|
GO:0060548 |
60 |
0.066
|
Worm |
|
|
cellular component assembly
|
GO:0022607 |
170 |
0.066
|
|
|
|
protein import
|
GO:0017038 |
3 |
0.065
|
|
|
|
blood vessel morphogenesis
|
GO:0048514 |
216 |
0.065
|
Mouse |
|
|
regulation of transferase activity
|
GO:0051338 |
16 |
0.065
|
|
|
|
neuron differentiation
|
GO:0030182 |
353 |
0.065
|
|
|
|
lipid biosynthetic process
|
GO:0008610 |
22 |
0.063
|
|
|
|
positive regulation of stress activated protein kinase signaling cascade
|
GO:0070304 |
3 |
0.063
|
|
|
|
negative regulation of signaling
|
GO:0023057 |
96 |
0.062
|
|
|
|
muscle tissue development
|
GO:0060537 |
110 |
0.062
|
|
|
|
positive regulation of signaling
|
GO:0023056 |
56 |
0.061
|
|
|
|
regulation of glucose import
|
GO:0046324 |
1 |
0.061
|
|
|
|
growth
|
GO:0040007 |
174 |
0.061
|
Fly |
|
|
organonitrogen compound metabolic process
|
GO:1901564 |
74 |
0.061
|
Mouse |
|
|
death
|
GO:0016265 |
121 |
0.060
|
|
|
|
retina development in camera type eye
|
GO:0060041 |
146 |
0.060
|
|
|
|
positive regulation of signal transduction
|
GO:0009967 |
56 |
0.060
|
|
|
|
modulation by virus of host morphology or physiology
|
GO:0019048 |
1 |
0.060
|
|
|
|
sensory organ morphogenesis
|
GO:0090596 |
200 |
0.060
|
|
|
|
germ line stem cell maintenance
|
GO:0030718 |
2 |
0.060
|
|
|
|
mechanosensory lateral line system development
|
GO:0048881 |
49 |
0.059
|
|
|
|
positive regulation of immune response
|
GO:0050778 |
11 |
0.059
|
|
|
|
sensory organ development
|
GO:0007423 |
393 |
0.059
|
|
|
|
protein modification process
|
GO:0036211 |
100 |
0.059
|
|
|
|
peptidyl serine modification
|
GO:0018209 |
2 |
0.059
|
|
|
|
cell morphogenesis involved in neuron differentiation
|
GO:0048667 |
163 |
0.058
|
Zebrafish |
|
|
neuron death
|
GO:0070997 |
21 |
0.058
|
|
|
|
positive regulation of cell communication
|
GO:0010647 |
56 |
0.058
|
|
|
|
circulatory system process
|
GO:0003013 |
87 |
0.058
|
Mouse |
|
|
negative regulation of cellular process
|
GO:0048523 |
283 |
0.058
|
Worm Fly |
|
|
peripheral nervous system development
|
GO:0007422 |
55 |
0.058
|
|
|
|
mesenchymal cell development
|
GO:0014031 |
78 |
0.057
|
|
|
|
signal transduction in absence of ligand
|
GO:0038034 |
1 |
0.057
|
|
|
|
response to peptide
|
GO:1901652 |
6 |
0.057
|
Fly |
|
|
lateral line system development
|
GO:0048925 |
76 |
0.056
|
|
|
|
cellular response to hypoxia
|
GO:0071456 |
1 |
0.056
|
Human Fly |
|
|
divalent inorganic cation homeostasis
|
GO:0072507 |
22 |
0.056
|
|
|
|
neuroblast proliferation
|
GO:0007405 |
2 |
0.056
|
|
|
|
digestive tract development
|
GO:0048565 |
265 |
0.056
|
|
|
|
establishment of endothelial barrier
|
GO:0061028 |
3 |
0.055
|
|
|
|
cellular lipid metabolic process
|
GO:0044255 |
36 |
0.055
|
|
|
|
regulation of programmed cell death
|
GO:0043067 |
101 |
0.055
|
|
|
|
multi organism process
|
GO:0051704 |
134 |
0.054
|
Fly |
|
|
maintenance of location
|
GO:0051235 |
4 |
0.054
|
|
|
|
modification of morphology or physiology of other organism involved in symbiotic interaction
|
GO:0051817 |
4 |
0.054
|
|
|
|
negative regulation of cell adhesion
|
GO:0007162 |
6 |
0.053
|
|
|
|
myeloid cell homeostasis
|
GO:0002262 |
56 |
0.053
|
Mouse |
|
|
neural crest cell development
|
GO:0014032 |
62 |
0.053
|
|
|
|
actomyosin structure organization
|
GO:0031032 |
53 |
0.053
|
|
|
|
epithelial cell migration
|
GO:0010631 |
25 |
0.053
|
|
|
|
positive regulation of apoptotic signaling pathway
|
GO:2001235 |
1 |
0.053
|
|
|
|
regulation of rna metabolic process
|
GO:0051252 |
224 |
0.053
|
Human Zebrafish Mouse Rat Worm Fly |
|
|
regulation of angiogenesis
|
GO:0045765 |
26 |
0.053
|
|
|
|
regulation of cellular protein metabolic process
|
GO:0032268 |
52 |
0.052
|
|
|
|
cytoskeleton organization
|
GO:0007010 |
96 |
0.052
|
|
|
|
cell morphogenesis involved in differentiation
|
GO:0000904 |
195 |
0.052
|
Zebrafish |
|
|
regulation of transcription elongation from rna polymerase ii promoter
|
GO:0034243 |
3 |
0.052
|
|
|
|
angiogenesis
|
GO:0001525 |
158 |
0.052
|
Mouse |
|
|
androgen metabolic process
|
GO:0008209 |
2 |
0.052
|
|
|
|
regulation of protein targeting
|
GO:1903533 |
2 |
0.052
|
|
|
|
phosphorus metabolic process
|
GO:0006793 |
109 |
0.051
|
|
|
|
muscle cell development
|
GO:0055001 |
115 |
0.051
|
|
|
|
regulation of kinase activity
|
GO:0043549 |
15 |
0.051
|
|
|
|
regulation of organ growth
|
GO:0046620 |
3 |
0.050
|
|
|
|
regulation of protein localization to nucleus
|
GO:1900180 |
2 |
0.050
|
|
|
|
positive regulation of nucleobase containing compound metabolic process
|
GO:0045935 |
69 |
0.050
|
Human Mouse Rat Fly |
|
|
long chain fatty acid metabolic process
|
GO:0001676 |
1 |
0.049
|
|
|
|
regulation of cell substrate adhesion
|
GO:0010810 |
1 |
0.049
|
|
|
|
stem cell differentiation
|
GO:0048863 |
117 |
0.049
|
|
|
|
positive regulation of leukocyte mediated immunity
|
GO:0002705 |
1 |
0.048
|
|
|
|
regulation of multicellular organismal process
|
GO:0051239 |
277 |
0.048
|
Mouse |
|
|
regulation of phosphorus metabolic process
|
GO:0051174 |
43 |
0.048
|
|
|
|
regulation of protein complex assembly
|
GO:0043254 |
3 |
0.048
|
|
|
|
hepaticobiliary system development
|
GO:0061008 |
98 |
0.048
|
|
|
|
regulation of metal ion transport
|
GO:0010959 |
4 |
0.047
|
|
|
|
regulation of intracellular signal transduction
|
GO:1902531 |
57 |
0.047
|
|
|
|
developmental pigmentation
|
GO:0048066 |
48 |
0.047
|
|
|
|
cell chemotaxis
|
GO:0060326 |
17 |
0.047
|
|
|
|
developmental growth
|
GO:0048589 |
166 |
0.047
|
|
|
|
modification of morphology or physiology of other organism
|
GO:0035821 |
4 |
0.047
|
|
|
|
regulation of response to stress
|
GO:0080134 |
36 |
0.047
|
|
|
|
regulation of cell migration
|
GO:0030334 |
40 |
0.047
|
Fly |
|
|
positive regulation of secretion
|
GO:0051047 |
1 |
0.047
|
|
|
|
positive regulation of cell adhesion
|
GO:0045785 |
1 |
0.046
|
|
|
|
regulation of production of molecular mediator of immune response
|
GO:0002700 |
1 |
0.046
|
|
|
|
regulation of hematopoietic progenitor cell differentiation
|
GO:1901532 |
1 |
0.046
|
|
|
|
multicellular organismal metabolic process
|
GO:0044236 |
2 |
0.046
|
|
|
|
single organism nuclear import
|
GO:1902593 |
3 |
0.046
|
|
|
|
response to virus
|
GO:0009615 |
21 |
0.045
|
|
|
|
striated muscle tissue development
|
GO:0014706 |
110 |
0.045
|
|
|
|
macromolecular complex subunit organization
|
GO:0043933 |
74 |
0.045
|
|
|
|
cell migration involved in heart development
|
GO:0060973 |
22 |
0.045
|
|
|
|
generation of precursor metabolites and energy
|
GO:0006091 |
5 |
0.045
|
|
|
|
regulation of cellular component movement
|
GO:0051270 |
55 |
0.044
|
Fly |
|
|
protein import into nucleus
|
GO:0006606 |
3 |
0.044
|
|
|
|
positive regulation of cell activation
|
GO:0050867 |
1 |
0.043
|
|
|
|
cellular response to extracellular stimulus
|
GO:0031668 |
2 |
0.043
|
Worm |
|
|
positive regulation of macromolecule metabolic process
|
GO:0010604 |
93 |
0.043
|
Human Mouse Rat Fly |
|
|
peptide transport
|
GO:0015833 |
1 |
0.043
|
|
|
|
protein localization to nucleus
|
GO:0034504 |
3 |
0.043
|
|
|
|
apoptotic process
|
GO:0006915 |
116 |
0.043
|
|
|
|
cellular protein metabolic process
|
GO:0044267 |
129 |
0.043
|
|
|
|
adherens junction organization
|
GO:0034332 |
4 |
0.042
|
|
|
|
positive regulation of endothelial cell proliferation
|
GO:0001938 |
1 |
0.042
|
|
|
|
cellular response to lipid
|
GO:0071396 |
39 |
0.042
|
|
|
|
signal transduction by phosphorylation
|
GO:0023014 |
18 |
0.042
|
|
|
|
response to estradiol
|
GO:0032355 |
6 |
0.042
|
|
|
|
cellular component biogenesis
|
GO:0044085 |
178 |
0.041
|
|
|
|
regulation of circadian rhythm
|
GO:0042752 |
4 |
0.041
|
|
|
|
epithelium migration
|
GO:0090132 |
25 |
0.041
|
|
|
|
regulation of catalytic activity
|
GO:0050790 |
55 |
0.041
|
|
|
|
regulation of anatomical structure morphogenesis
|
GO:0022603 |
130 |
0.041
|
|
|
|
response to glucose
|
GO:0009749 |
3 |
0.040
|
Zebrafish |
|
|
regulation of cardiac muscle tissue development
|
GO:0055024 |
1 |
0.040
|
|
|
|
protein targeting to nucleus
|
GO:0044744 |
3 |
0.040
|
|
|
|
cell cell signaling
|
GO:0007267 |
52 |
0.040
|
|
|
|
phosphate containing compound metabolic process
|
GO:0006796 |
108 |
0.040
|
|
|
|
regulation of signal transduction
|
GO:0009966 |
225 |
0.040
|
|
|
|
xenobiotic metabolic process
|
GO:0006805 |
4 |
0.040
|
|
|
|
macromolecule modification
|
GO:0043412 |
111 |
0.040
|
|
|
|
organic anion transport
|
GO:0015711 |
15 |
0.039
|
|
|
|
regulation of extrinsic apoptotic signaling pathway
|
GO:2001236 |
3 |
0.039
|
|
|
|
single organism organelle organization
|
GO:1902589 |
199 |
0.039
|
|
|
|
response to other organism
|
GO:0051707 |
97 |
0.039
|
|
|
|
nuclear transport
|
GO:0051169 |
4 |
0.039
|
|
|
|
stem cell development
|
GO:0048864 |
82 |
0.039
|
|
|
|
ovulation cycle process
|
GO:0022602 |
2 |
0.039
|
|
|
|
intrinsic apoptotic signaling pathway in response to oxidative stress
|
GO:0008631 |
2 |
0.039
|
|
|
|
regulation of cytoplasmic transport
|
GO:1903649 |
4 |
0.039
|
|
|
|
cell cycle g1 s phase transition
|
GO:0044843 |
1 |
0.039
|
|
|
|
reproduction
|
GO:0000003 |
40 |
0.039
|
Fly |
|
|
negative regulation of kinase activity
|
GO:0033673 |
4 |
0.038
|
|
|
|
cell morphogenesis
|
GO:0000902 |
289 |
0.038
|
Zebrafish |
|
|
establishment of protein localization to organelle
|
GO:0072594 |
4 |
0.038
|
|
|
|
skeletal system development
|
GO:0001501 |
181 |
0.038
|
|
|
|
macromolecule biosynthetic process
|
GO:0009059 |
227 |
0.038
|
Human Zebrafish Mouse Rat Worm Fly |
|
|
pyruvate metabolic process
|
GO:0006090 |
1 |
0.038
|
|
|
|
regulation of vasculature development
|
GO:1901342 |
33 |
0.038
|
|
|
|
response to lipopolysaccharide
|
GO:0032496 |
13 |
0.037
|
|
|
|
amine metabolic process
|
GO:0009308 |
2 |
0.037
|
|
|
|
positive regulation of leukocyte migration
|
GO:0002687 |
2 |
0.037
|
|
|
|
organic substance transport
|
GO:0071702 |
58 |
0.037
|
|
|
|
regulation of response to external stimulus
|
GO:0032101 |
31 |
0.037
|
|
|
|
response to decreased oxygen levels
|
GO:0036293 |
25 |
0.036
|
|
|
|
positive regulation of leukocyte chemotaxis
|
GO:0002690 |
1 |
0.036
|
|
|
|
regulation of phosphate metabolic process
|
GO:0019220 |
43 |
0.036
|
|
|
|
regulation of heart growth
|
GO:0060420 |
2 |
0.036
|
|
|
|
hormone mediated signaling pathway
|
GO:0009755 |
9 |
0.035
|
|
|
|
cartilage development
|
GO:0051216 |
96 |
0.035
|
|
|
|
positive regulation of biosynthetic process
|
GO:0009891 |
68 |
0.035
|
Human Mouse Rat Fly |
|
|
leukocyte chemotaxis
|
GO:0030595 |
12 |
0.035
|
|
|
|
cellular response to organonitrogen compound
|
GO:0071417 |
5 |
0.035
|
Fly |
|
|
positive regulation of neural precursor cell proliferation
|
GO:2000179 |
1 |
0.035
|
|
|
|
heart contraction
|
GO:0060047 |
71 |
0.035
|
Mouse |
|
|
cellular response to biotic stimulus
|
GO:0071216 |
3 |
0.035
|
|
|
|
nucleocytoplasmic transport
|
GO:0006913 |
4 |
0.035
|
|
|
|
regulation of nucleocytoplasmic transport
|
GO:0046822 |
2 |
0.034
|
|
|
|
meiotic nuclear division
|
GO:0007126 |
4 |
0.034
|
|
|
|
positive regulation of cell cycle
|
GO:0045787 |
3 |
0.034
|
|
|
|
cardiac muscle tissue development
|
GO:0048738 |
48 |
0.034
|
|
|
|
response to wounding
|
GO:0009611 |
116 |
0.034
|
|
|
|
oxidative demethylation
|
GO:0070989 |
1 |
0.034
|
|
|
|
response to organonitrogen compound
|
GO:0010243 |
12 |
0.034
|
Fly |
|
|
response to acid chemical
|
GO:0001101 |
17 |
0.034
|
|
|
|
lymphocyte homeostasis
|
GO:0002260 |
1 |
0.033
|
|
|
|
positive regulation of myeloid cell differentiation
|
GO:0045639 |
2 |
0.033
|
|
|
|
ovarian follicle development
|
GO:0001541 |
2 |
0.033
|
|
|
|
carbohydrate homeostasis
|
GO:0033500 |
1 |
0.033
|
|
|
|
response to biotic stimulus
|
GO:0009607 |
97 |
0.033
|
|
|
|
production of molecular mediator of immune response
|
GO:0002440 |
2 |
0.033
|
|
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
0 |
0.033
|
|
|
|
muscle system process
|
GO:0003012 |
20 |
0.033
|
|
|
|
immune response activating signal transduction
|
GO:0002757 |
5 |
0.033
|
|
|
|
cellular ketone metabolic process
|
GO:0042180 |
11 |
0.033
|
|
|
|
negative regulation of cell communication
|
GO:0010648 |
96 |
0.033
|
|
|
|
protein complex biogenesis
|
GO:0070271 |
30 |
0.033
|
|
|
|
regulation of protein metabolic process
|
GO:0051246 |
56 |
0.033
|
|
|
|
response to peptide hormone
|
GO:0043434 |
6 |
0.032
|
Fly |
|
|
protein complex assembly
|
GO:0006461 |
30 |
0.032
|
|
|
|
response to ketone
|
GO:1901654 |
1 |
0.032
|
|
|
|
regulation of protein modification by small protein conjugation or removal
|
GO:1903320 |
3 |
0.032
|
|
|
|
chemotaxis
|
GO:0006935 |
104 |
0.032
|
Zebrafish |
|
|
autophagy
|
GO:0006914 |
4 |
0.032
|
Fly |
|
|
regulation of reproductive process
|
GO:2000241 |
4 |
0.032
|
|
|
|
establishment of localization in cell
|
GO:0051649 |
77 |
0.032
|
|
|
|
immune system process
|
GO:0002376 |
241 |
0.032
|
Mouse |
|
|
regulation of cell development
|
GO:0060284 |
100 |
0.032
|
|
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
0 |
0.032
|
|
|
|
positive regulation of catabolic process
|
GO:0009896 |
4 |
0.032
|
Fly |
|
|
erythrocyte differentiation
|
GO:0030218 |
54 |
0.032
|
Mouse |
|
|
regulation of transmembrane transporter activity
|
GO:0022898 |
2 |
0.032
|
|
|
|
regulation of cell growth
|
GO:0001558 |
29 |
0.032
|
Fly |
|
|
g1 s transition of mitotic cell cycle
|
GO:0000082 |
1 |
0.032
|
|
|
|
transmission of nerve impulse
|
GO:0019226 |
19 |
0.031
|
|
|
|
meiosis i
|
GO:0007127 |
1 |
0.031
|
|
|
|
positive regulation of cell migration
|
GO:0030335 |
11 |
0.031
|
|
|
|
regulation of dna templated transcription elongation
|
GO:0032784 |
3 |
0.031
|
|
|
|
steroid hormone mediated signaling pathway
|
GO:0043401 |
9 |
0.031
|
|
|
|
gland development
|
GO:0048732 |
143 |
0.031
|
|
|
|
response to vitamin
|
GO:0033273 |
3 |
0.031
|
|
|
|
intracellular signal transduction
|
GO:0035556 |
85 |
0.030
|
|
|
|
positive regulation of phosphate metabolic process
|
GO:0045937 |
21 |
0.030
|
|
|
|
signal transduction
|
GO:0007165 |
455 |
0.030
|
|
|
|
reactive nitrogen species metabolic process
|
GO:2001057 |
0 |
0.030
|
|
|
|
mesenchyme development
|
GO:0060485 |
127 |
0.030
|
|
|
|
regulation of dna replication
|
GO:0006275 |
3 |
0.030
|
|
|
|
cellular metal ion homeostasis
|
GO:0006875 |
16 |
0.030
|
|
|
|
response to carbohydrate
|
GO:0009743 |
3 |
0.030
|
Zebrafish |
|
|
cell type specific apoptotic process
|
GO:0097285 |
22 |
0.030
|
|
|
|
striated muscle cell differentiation
|
GO:0051146 |
129 |
0.030
|
|
|
|
glucose homeostasis
|
GO:0042593 |
1 |
0.030
|
|
|
|
negative regulation of macromolecule metabolic process
|
GO:0010605 |
76 |
0.029
|
|
|
|
response to alcohol
|
GO:0097305 |
14 |
0.029
|
|
|
|
positive regulation of neuron apoptotic process
|
GO:0043525 |
1 |
0.029
|
|
|
|
regulation of ion transport
|
GO:0043269 |
22 |
0.029
|
|
