Danio rerio

130 known processes

epha4a

eph receptor A4a

(Aliases: apha3,zek2,EphA4,epha3,MGC109882,rtk1,sb:cb246,zgc:109882,ek2)

epha4a biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
brain development GO:0007420 293 0.995
central nervous system development GO:0007417 387 0.989
rhombomere development GO:0021546 19 0.967
tube morphogenesis GO:0035239 349 0.965
neuron projection morphogenesis GO:0048812 161 0.954
negative regulation of axon extension GO:0030517 7 0.944
cellular component morphogenesis GO:0032989 336 0.941
regulation of collateral sprouting of intact axon in response to injury GO:0048683 2 0.928
neuron differentiation GO:0030182 353 0.928
anatomical structure arrangement GO:0048532 2 0.905
axonogenesis GO:0007409 152 0.901
regulation of rna metabolic process GO:0051252 224 0.900
rhombomere morphogenesis GO:0021593 17 0.861
rhombomere boundary formation GO:0021654 10 0.844
forebrain development GO:0030900 96 0.826
head development GO:0060322 303 0.825
regulation of response to stimulus GO:0048583 269 0.819
negative regulation of neuron projection regeneration GO:0070571 4 0.815
regulation of cell differentiation GO:0045595 142 0.805
nucleic acid templated transcription GO:0097659 181 0.759
regionalization GO:0003002 274 0.740
diencephalon development GO:0021536 58 0.737
rhombomere formation GO:0021594 12 0.736
regulation of macromolecule metabolic process GO:0060255 317 0.695
formation of anatomical boundary GO:0048859 14 0.675
wound healing GO:0042060 90 0.670
positive regulation of transcription from rna polymerase ii promoter GO:0045944 22 0.664
regulation of transcription from rna polymerase ii promoter GO:0006357 114 0.658
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.651
axon development GO:0061564 166 0.649
segmentation GO:0035282 97 0.647
regulation of protein catabolic process GO:0042176 1 0.643
negative regulation of axon guidance GO:1902668 1 0.643
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 50 0.639
cell projection morphogenesis GO:0048858 244 0.634
negative regulation of collateral sprouting of intact axon in response to injury GO:0048685 2 0.626
pronephros development GO:0048793 69 0.598
eye development GO:0001654 277 0.587
Mouse
neuron development GO:0048666 262 0.586
regulation of protein localization to nucleus GO:1900180 2 0.579
regulation of cell communication GO:0010646 232 0.557
Human
phosphate containing compound metabolic process GO:0006796 108 0.555
Human Rat Worm
regulation of mechanoreceptor differentiation GO:0045631 1 0.548
positive regulation of gene expression GO:0010628 71 0.543
transcription from rna polymerase ii promoter GO:0006366 80 0.528
blood vessel development GO:0001568 246 0.522
Human Zebrafish
renal system development GO:0072001 94 0.509
striated muscle cell differentiation GO:0051146 129 0.499
regulation of signal transduction GO:0009966 225 0.478
Human
muscle structure development GO:0061061 196 0.475
embryonic organ development GO:0048568 381 0.474
vasculature development GO:0001944 278 0.464
Human Zebrafish
generation of neurons GO:0048699 385 0.464
cell morphogenesis involved in differentiation GO:0000904 195 0.448
cell surface receptor signaling pathway GO:0007166 325 0.445
Human
kidney development GO:0001822 92 0.443
nephron development GO:0072006 31 0.438
retinal ganglion cell axon guidance GO:0031290 35 0.429
Mouse
regulation of wnt signaling pathway involved in digestive tract morphogenesis GO:2000056 2 0.425
regulation of wnt signaling pathway planar cell polarity pathway GO:2000095 2 0.424
gastrulation GO:0007369 208 0.420
protein localization to nucleus GO:0034504 3 0.418
extrinsic apoptotic signaling pathway GO:0097191 3 0.405
chordate embryonic development GO:0043009 271 0.403
axon regeneration GO:0031103 14 0.402
collateral sprouting of intact axon in response to injury GO:0048673 2 0.397
regulation of protein targeting GO:1903533 2 0.396
cell motility GO:0048870 244 0.393
Human Zebrafish Mouse
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.387
biosynthetic process GO:0009058 294 0.386
positive regulation of transcription dna templated GO:0045893 57 0.376
positive regulation of striated muscle cell differentiation GO:0051155 1 0.368
negative regulation of response to stimulus GO:0048585 104 0.366
response to stress GO:0006950 263 0.359
intracellular signal transduction GO:0035556 85 0.335
Human
central nervous system neuron axonogenesis GO:0021955 18 0.331
Mouse
regulation of nucleic acid templated transcription GO:1903506 213 0.322
negative regulation of axonogenesis GO:0050771 7 0.319
cellular biosynthetic process GO:0044249 286 0.319
regeneration GO:0031099 91 0.308
macromolecule biosynthetic process GO:0009059 227 0.308
negative regulation of collateral sprouting GO:0048671 2 0.305
digestive tract morphogenesis GO:0048546 231 0.304
regulation of inner ear receptor cell differentiation GO:2000980 1 0.301
regulation of intracellular protein transport GO:0033157 3 0.291
regulation of protein import into nucleus GO:0042306 2 0.290
neuron projection guidance GO:0097485 86 0.284
Mouse Worm
embryonic limb morphogenesis GO:0030326 2 0.276
positive regulation of biosynthetic process GO:0009891 68 0.268
somite development GO:0061053 96 0.266
regulation of gene expression GO:0010468 265 0.264
transcription dna templated GO:0006351 181 0.263
regulation of glial cell differentiation GO:0045685 4 0.261
regulation of anatomical structure morphogenesis GO:0022603 130 0.259
regulation of protein transport GO:0051223 3 0.259
protein import into nucleus GO:0006606 3 0.258
regulation of response to stress GO:0080134 36 0.242
negative regulation of chemotaxis GO:0050922 4 0.241
nucleic acid metabolic process GO:0090304 244 0.240
regulation of collateral sprouting GO:0048670 7 0.240
cell proliferation in hindbrain GO:0021534 4 0.238
positive regulation of muscle cell differentiation GO:0051149 1 0.238
inner ear development GO:0048839 126 0.235
dorsal ventral pattern formation GO:0009953 125 0.235
cellular component movement GO:0006928 335 0.235
Human Zebrafish Mouse Worm
female sex differentiation GO:0046660 4 0.229
response to nutrient GO:0007584 3 0.226
facial nerve morphogenesis GO:0021610 1 0.222
angioblast cell migration involved in selective angioblast sprouting GO:0035475 4 0.220
Zebrafish
positive regulation of striated muscle tissue development GO:0045844 1 0.212
camera type eye development GO:0043010 222 0.212
Mouse
glycoprotein biosynthetic process GO:0009101 21 0.209
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.209
urogenital system development GO:0001655 97 0.206
axis elongation involved in somitogenesis GO:0090245 2 0.205
nephric duct development GO:0072176 13 0.205
rna metabolic process GO:0016070 219 0.202
negative regulation of axon extension involved in axon guidance GO:0048843 1 0.201
type b pancreatic cell proliferation GO:0044342 1 0.201
regulation of collateral sprouting in absence of injury GO:0048696 4 0.201
ameboidal type cell migration GO:0001667 143 0.200
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 42 0.200
Human
regulation of multicellular organismal development GO:2000026 223 0.199
positive regulation of muscle tissue development GO:1901863 1 0.198
cell part morphogenesis GO:0032990 246 0.198
cell projection organization GO:0030030 284 0.193
regulation of axonogenesis GO:0050770 32 0.193
regulation of establishment of protein localization GO:0070201 4 0.190
regulation of catenin import into nucleus GO:0035412 2 0.188
positive regulation of signal transduction GO:0009967 56 0.183
regulation of transcription dna templated GO:0006355 213 0.181
positive regulation of cellular process GO:0048522 201 0.175
Mouse
anterior posterior axon guidance GO:0033564 5 0.174
notochord development GO:0030903 54 0.169
cellular response to prostaglandin stimulus GO:0071379 3 0.167
cellular response to retinoic acid GO:0071300 1 0.167
neuron fate commitment GO:0048663 26 0.165
positive regulation of biological process GO:0048518 253 0.163
Mouse
regulation of macromolecule biosynthetic process GO:0010556 225 0.162
stem cell development GO:0048864 82 0.162
negative regulation of anterior neural cell fate commitment of the neural plate GO:0022001 1 0.159
negative regulation of signaling GO:0023057 96 0.158
negative regulation of gliogenesis GO:0014014 1 0.157
mechanoreceptor differentiation GO:0042490 37 0.156
renal tubule morphogenesis GO:0061333 1 0.154
bmp signaling pathway GO:0030509 52 0.153
facial nerve development GO:0021561 3 0.153
epithelial cell morphogenesis GO:0003382 2 0.150
appendage development GO:0048736 80 0.149
angiogenesis GO:0001525 158 0.148
Human
embryonic pattern specification GO:0009880 44 0.144
morphogenesis of embryonic epithelium GO:0016331 30 0.143
Worm
mammillary body development GO:0021767 4 0.143
forebrain anterior posterior pattern specification GO:0021797 3 0.139
axon extension GO:0048675 45 0.139
blood vessel morphogenesis GO:0048514 216 0.139
Human Zebrafish
negative regulation of locomotion GO:0040013 18 0.138
hindbrain development GO:0030902 91 0.137
positive regulation of nucleic acid templated transcription GO:1903508 57 0.136
regulation of extrinsic apoptotic signaling pathway GO:2001236 3 0.133
positive regulation of rna biosynthetic process GO:1902680 57 0.132
negative regulation of stem cell differentiation GO:2000737 2 0.129
signal transduction by phosphorylation GO:0023014 18 0.127
Human
response to wounding GO:0009611 116 0.126
response to external stimulus GO:0009605 264 0.126
nephron morphogenesis GO:0072028 2 0.126
negative regulation of protein serine threonine kinase activity GO:0071901 2 0.125
protein metabolic process GO:0019538 183 0.125
Human Rat Worm
positive regulation of cell activation GO:0050867 1 0.124
blood vessel endothelial cell migration GO:0043534 18 0.122
cell proliferation in forebrain GO:0021846 3 0.122
kidney epithelium development GO:0072073 23 0.121
single organism nuclear import GO:1902593 3 0.119
sensory organ development GO:0007423 393 0.118
Mouse
regulation of biosynthetic process GO:0009889 250 0.118
axon guidance GO:0007411 86 0.117
Mouse Worm
negative regulation of cell migration GO:0030336 17 0.116
astrocyte differentiation GO:0048708 1 0.114
regulation of multicellular organismal process GO:0051239 277 0.114
tissue regeneration GO:0042246 74 0.114
taxis GO:0042330 109 0.113
Human Mouse Worm
hematopoietic stem cell migration GO:0035701 4 0.110
cartilage development GO:0051216 96 0.109
canonical wnt signaling pathway involved in heart development GO:0061316 1 0.109
negative regulation of neutrophil migration GO:1902623 3 0.108
larval development GO:0002164 2 0.106
skeletal system morphogenesis GO:0048705 102 0.106
wnt signaling pathway involved in somitogenesis GO:0090244 2 0.106
cellular protein metabolic process GO:0044267 129 0.103
Human Rat Worm
regulation of cell cycle process GO:0010564 20 0.102
positive regulation of transport GO:0051050 2 0.100
ossification GO:0001503 23 0.100
nephron tubule morphogenesis GO:0072078 1 0.100
regulation of metabolic process GO:0019222 359 0.098
Human
ear development GO:0043583 127 0.098
regulation of oligodendrocyte differentiation GO:0048713 1 0.098
regulation of bmp signaling pathway GO:0030510 39 0.097
negative regulation of cellular process GO:0048523 283 0.097
central nervous system segmentation GO:0035283 6 0.097
regulation of canonical wnt signaling pathway GO:0060828 34 0.096
mesodermal cell migration GO:0008078 12 0.096
mesenchyme development GO:0060485 127 0.095
dendrite guidance GO:0070983 0 0.095
nuclear transport GO:0051169 4 0.095
nucleobase containing compound biosynthetic process GO:0034654 205 0.095
forebrain neuron development GO:0021884 7 0.094
female gonad development GO:0008585 4 0.093
brain segmentation GO:0035284 6 0.093
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 68 0.092
regulation of nucleocytoplasmic transport GO:0046822 2 0.090
negative regulation of mapk cascade GO:0043409 4 0.089
regulation of signaling GO:0023051 235 0.088
Human
neuron projection development GO:0031175 180 0.088
regulation of protein binding GO:0043393 3 0.087
protein modification process GO:0036211 100 0.087
Human Rat Worm
negative regulation of anterior neural cell fate commitment of the neural plate by wnt signaling pathway GO:0022002 1 0.087
developmental process involved in reproduction GO:0003006 27 0.086
Worm
embryonic cranial skeleton morphogenesis GO:0048701 90 0.084
regulation of cell projection organization GO:0031344 44 0.084
regulation of protein ubiquitination GO:0031396 3 0.084
muscle cell differentiation GO:0042692 139 0.084
cellular response to chemical stimulus GO:0070887 157 0.084
Human Mouse
epithelial tube formation GO:0072175 19 0.083
response to vitamin GO:0033273 3 0.083
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.080
positive regulation of muscle organ development GO:0048636 1 0.080
rna biosynthetic process GO:0032774 181 0.079
positive regulation of axon guidance GO:1902669 1 0.078
positive regulation of peptidyl tyrosine phosphorylation GO:0050731 1 0.077
lymphoid lineage cell migration into thymus GO:0097535 4 0.077
regulation of rna biosynthetic process GO:2001141 213 0.077
negative regulation of apoptotic process GO:0043066 55 0.077
pronephric glomerulus development GO:0039021 13 0.076
sensory neuron axon guidance GO:0097374 3 0.076
response to chemical GO:0042221 320 0.075
Human Mouse Worm
cellular macromolecule biosynthetic process GO:0034645 224 0.074
heart field specification GO:0003128 1 0.073
regulation of ossification GO:0030278 5 0.073
epithelial cell differentiation involved in kidney development GO:0035850 13 0.073
adult behavior GO:0030534 2 0.072
establishment of protein localization to organelle GO:0072594 4 0.071
negative regulation of extrinsic apoptotic signaling pathway GO:2001237 2 0.071
lymphoid lineage cell migration GO:0097534 4 0.071
regulation of developmental process GO:0050793 247 0.070
positive regulation of cyclin dependent protein serine threonine kinase activity GO:0045737 1 0.069
negative regulation of cellular component movement GO:0051271 18 0.069
mononuclear cell proliferation GO:0032943 1 0.069
positive regulation of rna metabolic process GO:0051254 59 0.068
somitogenesis GO:0001756 87 0.068
forebrain neuron differentiation GO:0021879 14 0.067
connective tissue development GO:0061448 99 0.067
regulation of endodermal cell fate specification GO:0042663 15 0.067
hypothalamus development GO:0021854 14 0.066
leukocyte proliferation GO:0070661 1 0.065
stem cell maintenance GO:0019827 4 0.065
negative regulation of kinase activity GO:0033673 4 0.064
positive regulation of oligodendrocyte differentiation GO:0048714 1 0.063
developmental growth GO:0048589 166 0.063
positive regulation of axon extension involved in axon guidance GO:0048842 1 0.062
response to drug GO:0042493 3 0.062
negative regulation of neuron differentiation GO:0045665 10 0.062
regulation of cell morphogenesis involved in differentiation GO:0010769 38 0.061
protein import GO:0017038 3 0.061
anterior commissure morphogenesis GO:0021960 3 0.061
lateral mesoderm development GO:0048368 23 0.060
neuroblast proliferation GO:0007405 2 0.060
cell morphogenesis GO:0000902 289 0.059
hematopoietic or lymphoid organ development GO:0048534 191 0.059
regulation of extent of cell growth GO:0061387 29 0.059
kidney morphogenesis GO:0060993 15 0.059
response to prostaglandin GO:0034694 5 0.058
nucleocytoplasmic transport GO:0006913 4 0.058
tissue migration GO:0090130 37 0.058
regulation of cell size GO:0008361 29 0.058
embryonic skeletal system morphogenesis GO:0048704 93 0.058
gene expression GO:0010467 252 0.058
amine metabolic process GO:0009308 2 0.058
ear morphogenesis GO:0042471 64 0.057
regulation of protein modification by small protein conjugation or removal GO:1903320 3 0.057
development of primary female sexual characteristics GO:0046545 4 0.056
hepatic duct development GO:0061011 2 0.056
negative regulation of cell motility GO:2000146 17 0.055
forebrain generation of neurons GO:0021872 14 0.055
cell cycle g1 s phase transition GO:0044843 1 0.055
negative regulation of neutrophil chemotaxis GO:0090024 3 0.054
epithelium migration GO:0090132 25 0.054
single organism cell adhesion GO:0098602 29 0.054
determination of bilateral symmetry GO:0009855 204 0.054
regulation of primary metabolic process GO:0080090 311 0.054
cellular response to organic substance GO:0071310 105 0.053
regulation of kinase activity GO:0043549 15 0.053
cellular response to growth factor stimulus GO:0071363 39 0.053
fourth ventricle development GO:0021592 8 0.053
single organism metabolic process GO:0044710 217 0.053
Human Fly
peripheral nervous system neuron differentiation GO:0048934 28 0.052
mesenchymal cell development GO:0014031 78 0.052
phagocytosis GO:0006909 3 0.052
regulation of embryonic development GO:0045995 47 0.052
protein n linked glycosylation GO:0006487 1 0.051
stem cell proliferation GO:0072089 4 0.051
nuclear import GO:0051170 3 0.051
negative regulation of biological process GO:0048519 304 0.050
single organism organelle organization GO:1902589 199 0.050
nitrogen compound metabolic process GO:0006807 319 0.049
embryo development ending in birth or egg hatching GO:0009792 271 0.049
Worm
negative regulation of intracellular signal transduction GO:1902532 22 0.049
morphogenesis of an epithelium GO:0002009 333 0.048
Zebrafish Worm
cell cycle GO:0007049 93 0.048
cell projection assembly GO:0030031 64 0.046
gland development GO:0048732 143 0.046
negative regulation of jnk cascade GO:0046329 1 0.046
organic cyclic compound metabolic process GO:1901360 301 0.046
Fly
post embryonic organ development GO:0048569 4 0.045
protein secretion GO:0009306 1 0.045
dendrite development GO:0016358 9 0.045
Mouse
stem cell differentiation GO:0048863 117 0.044
cell fate commitment GO:0045165 99 0.044
cellular aromatic compound metabolic process GO:0006725 295 0.044
Fly
chemotaxis GO:0006935 104 0.044
Human Mouse Worm
positive regulation of macromolecule biosynthetic process GO:0010557 59 0.044
skeletal system development GO:0001501 181 0.044
regulation of axon guidance GO:1902667 8 0.043
regulation of cytoplasmic transport GO:1903649 4 0.043
retinoic acid metabolic process GO:0042573 9 0.043
multicellular organismal reproductive process GO:0048609 35 0.043
Worm
organic substance biosynthetic process GO:1901576 289 0.043
cell division GO:0051301 20 0.043
regulation of apoptotic process GO:0042981 98 0.042
striated muscle cell development GO:0055002 108 0.042
positive regulation of multicellular organismal process GO:0051240 52 0.042
Mouse
positive regulation of embryonic development GO:0040019 3 0.042
lymphocyte activation GO:0046649 10 0.042
regulation of cytokine production GO:0001817 3 0.041
negative regulation of cell death GO:0060548 60 0.041
regulation of cellular response to growth factor stimulus GO:0090287 35 0.041
cell cell signaling GO:0007267 52 0.041
Mouse
positive regulation of gastrulation GO:2000543 2 0.041
enzyme linked receptor protein signaling pathway GO:0007167 106 0.040
Human
locomotion GO:0040011 313 0.040
Human Zebrafish Mouse Worm
macromolecule glycosylation GO:0043413 9 0.039
regulation of protein phosphorylation GO:0001932 18 0.039
positive chemotaxis GO:0050918 5 0.039
negative regulation of signal transduction GO:0009968 94 0.038
wnt signaling pathway planar cell polarity pathway GO:0060071 4 0.038
response to hexose GO:0009746 3 0.038
regulation of establishment of planar polarity GO:0090175 4 0.038
negative regulation of map kinase activity GO:0043407 2 0.038
nephron epithelium development GO:0072009 16 0.038
apoptotic process GO:0006915 116 0.038
peptidyl tyrosine modification GO:0018212 5 0.038
Human Rat Worm
cell differentiation involved in kidney development GO:0061005 13 0.037
cellular response to nutrient levels GO:0031669 2 0.037
regulation of biological quality GO:0065008 263 0.037
maintenance of location GO:0051235 4 0.037
negative chemotaxis GO:0050919 1 0.036
cellular macromolecule metabolic process GO:0044260 391 0.036
Human Rat Worm
regulation of cellular response to stress GO:0080135 20 0.036
regulation of gastrulation GO:0010470 24 0.035
response to monosaccharide GO:0034284 3 0.035
regulation of epithelial to mesenchymal transition GO:0010717 3 0.035
proximal distal pattern formation GO:0009954 1 0.035
regulation of cell adhesion GO:0030155 15 0.035
positive regulation of cell differentiation GO:0045597 30 0.035
embryonic viscerocranium morphogenesis GO:0048703 52 0.035
response to vitamin b3 GO:0033552 2 0.035
olfactory bulb axon guidance GO:0071678 3 0.035
adrenal gland development GO:0030325 10 0.034
striated muscle tissue development GO:0014706 110 0.034
heterocycle metabolic process GO:0046483 290 0.034
positive regulation of macromolecule metabolic process GO:0010604 93 0.034
positive regulation of nucleobase containing compound metabolic process GO:0045935 69 0.033
cardiac cell fate commitment GO:0060911 1 0.033
regulation of cell morphogenesis GO:0022604 42 0.033
epithelial tube morphogenesis GO:0060562 148 0.033
nucleobase containing compound metabolic process GO:0006139 274 0.033
central nervous system myelination GO:0022010 2 0.033
response to organic substance GO:0010033 153 0.033
regulation of cell activation GO:0050865 1 0.033
negative regulation of cell growth GO:0030308 7 0.033
sex determination GO:0007530 1 0.033
response to growth factor GO:0070848 39 0.033
bone remodeling GO:0046849 2 0.032
ubiquitin dependent protein catabolic process GO:0006511 3 0.032
regulation of phosphorylation GO:0042325 26 0.032
Human
cellular response to extracellular stimulus GO:0031668 2 0.032
cellular protein modification process GO:0006464 100 0.031
Human Rat Worm
compound eye development GO:0048749 2 0.031
immune system development GO:0002520 191 0.031
endocrine system development GO:0035270 65 0.031
single organism localization GO:1902578 225 0.031
protein targeting to nucleus GO:0044744 3 0.031
negative regulation of bmp signaling pathway GO:0030514 13 0.031
positive regulation of response to stimulus GO:0048584 80 0.031
b cell differentiation GO:0030183 1 0.031
endothelial cell migration GO:0043542 19 0.031
segment specification GO:0007379 12 0.030
coagulation GO:0050817 13 0.030
embryonic skeletal joint development GO:0072498 3 0.030
negative regulation of granulocyte chemotaxis GO:0071623 3 0.030
positive regulation of cellular metabolic process GO:0031325 94 0.030
macromolecule modification GO:0043412 111 0.029
Human Rat Worm
secondary metabolic process GO:0019748 3 0.029
Fly
body morphogenesis GO:0010171 16 0.029
Worm
nephron tubule epithelial cell differentiation GO:0072160 1 0.029
formation of primary germ layer GO:0001704 62 0.029
cellular response to fibroblast growth factor stimulus GO:0044344 22 0.029
embryonic epithelial tube formation GO:0001838 17 0.029
glycoprotein metabolic process GO:0009100 23 0.029
mesoderm development GO:0007498 88 0.029
cellular response to external stimulus GO:0071496 2 0.029
forebrain regionalization GO:0021871 4 0.028
pronephric nephron development GO:0039019 14 0.028
regulation of cyclin dependent protein serine threonine kinase activity GO:0000079 1 0.028
negative regulation of programmed cell death GO:0043069 58 0.028
negative regulation of protein phosphorylation GO:0001933 4 0.028
pronephric duct development GO:0039022 13 0.028
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.028
regulation of cardiac muscle tissue development GO:0055024 1 0.028
cell migration involved in sprouting angiogenesis GO:0002042 8 0.027
regulation of organ morphogenesis GO:2000027 35 0.027
negative regulation of leukocyte chemotaxis GO:0002689 3 0.027
neural crest cell differentiation GO:0014033 72 0.027
positive regulation of catalytic activity GO:0043085 25 0.027
positive regulation of cell fate commitment GO:0010455 1 0.027
extracellular fibril organization GO:0043206 1 0.027
signal transduction GO:0007165 455 0.027
Human Mouse
blood coagulation GO:0007596 12 0.027
muscle tissue development GO:0060537 110 0.027
regulation of nitrogen compound metabolic process GO:0051171 251 0.026
heterocycle biosynthetic process GO:0018130 215 0.026
ectoderm development GO:0007398 9 0.026
somatic stem cell maintenance GO:0035019 1 0.026
embryonic organ morphogenesis GO:0048562 274 0.026
regulation of reproductive process GO:2000241 4 0.026
Worm
regulation of intracellular signal transduction GO:1902531 57 0.026
Human
regulation of smoothened signaling pathway GO:0008589 18 0.026
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.026
protein phosphorylation GO:0006468 47 0.025
Human Rat Worm
negative regulation of axon regeneration GO:0048681 4 0.025
exocrine system development GO:0035272 28 0.025
negative regulation of developmental process GO:0051093 65 0.025
endodermal cell fate determination GO:0007493 2 0.025
gliogenesis GO:0042063 45 0.025
negative regulation of molecular function GO:0044092 23 0.025
regulation of endodermal cell differentiation GO:1903224 15 0.025
response to glucocorticoid GO:0051384 1 0.025
negative regulation of cell morphogenesis involved in differentiation GO:0010771 8 0.025
inner ear morphogenesis GO:0042472 63 0.025
regulation of protein metabolic process GO:0051246 56 0.025
patterning of lymph vessels GO:0060854 1 0.024
thalamus development GO:0021794 6 0.024
regulation of wnt signaling pathway GO:0030111 53 0.024
positive regulation of apoptotic signaling pathway GO:2001235 1 0.024
cellular ketone metabolic process GO:0042180 11 0.024
regulation of behavior GO:0050795 24 0.024
localization of cell GO:0051674 244 0.024
Human Zebrafish Mouse
cell cell recognition GO:0009988 1 0.023
anterior head development GO:0097065 2 0.023
response to lipid GO:0033993 60 0.023
mesodermal cell fate specification GO:0007501 12 0.023
positive regulation of metabolic process GO:0009893 108 0.023
endodermal digestive tract morphogenesis GO:0061031 2 0.023
fin development GO:0033333 77 0.023
response to carbohydrate GO:0009743 3 0.023
canonical wnt signaling pathway involved in neural plate anterior posterior pattern formation GO:0060823 4 0.023
cardiac muscle cell differentiation GO:0055007 30 0.023
wnt signaling pathway involved in digestive tract morphogenesis GO:0044333 4 0.023
cellular amine metabolic process GO:0044106 2 0.023
axonal fasciculation GO:0007413 11 0.022
reproduction GO:0000003 40 0.022
Worm
osteoclast differentiation GO:0030316 1 0.022
developmental cell growth GO:0048588 52 0.022
regulation of cell death GO:0010941 103 0.022
Human
brain morphogenesis GO:0048854 18 0.022
motor neuron axon guidance GO:0008045 23 0.021
skin development GO:0043588 54 0.021
positive regulation of cellular amine metabolic process GO:0033240 0 0.021
mitotic cell cycle GO:0000278 64 0.021
dorsal ventral neural tube patterning GO:0021904 1 0.021
inner ear receptor cell differentiation GO:0060113 29 0.021
neuron fate specification GO:0048665 20 0.021
lamellipodium assembly GO:0030032 1 0.021
selective angioblast sprouting GO:0035474 5 0.020
Zebrafish
hair cell differentiation GO:0035315 32 0.020
peripheral nervous system neuron development GO:0048935 22 0.020
negative regulation of extrinsic apoptotic signaling pathway in absence of ligand GO:2001240 1 0.020
regulation of organ growth GO:0046620 3 0.020
b cell activation GO:0042113 2 0.020
distal tubule development GO:0072017 1 0.020
hindbrain morphogenesis GO:0021575 22 0.020
glomerulus development GO:0032835 27 0.020

epha4a disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.051
reproductive system disease DOID:15 0 0.051
reproductive organ cancer DOID:193 0 0.040
female reproductive organ cancer DOID:120 0 0.040
cancer DOID:162 0 0.040
disease of cellular proliferation DOID:14566 0 0.040
organ system cancer DOID:0050686 0 0.040
nervous system disease DOID:863 0 0.040