Danio rerio

32 known processes

ephb4a

eph receptor B4a

(Aliases: cb646,rtk5,ephB4,MGC171234,MGC136748)

ephb4a biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cell motility GO:0048870 244 0.954
localization of cell GO:0051674 244 0.857
neuron projection development GO:0031175 180 0.759
Zebrafish Worm
blood vessel morphogenesis GO:0048514 216 0.746
regulation of collateral sprouting of intact axon in response to injury GO:0048683 2 0.664
Zebrafish
angioblast cell migration involved in selective angioblast sprouting GO:0035475 4 0.650
cellular aromatic compound metabolic process GO:0006725 295 0.643
Fly
blood vessel development GO:0001568 246 0.620
immune system development GO:0002520 191 0.589
cellular component movement GO:0006928 335 0.566
regulation of biological quality GO:0065008 263 0.544
Zebrafish
neuron differentiation GO:0030182 353 0.496
Zebrafish Worm
cell surface receptor signaling pathway GO:0007166 325 0.491
Human Mouse
rhombomere formation GO:0021594 12 0.490
Zebrafish
angioblast cell migration GO:0035476 9 0.416
cell migration GO:0016477 237 0.407
cell morphogenesis GO:0000902 289 0.406
Zebrafish Worm
vasculature development GO:0001944 278 0.402
eye development GO:0001654 277 0.366
response to chemical GO:0042221 320 0.345
Worm
embryonic organ development GO:0048568 381 0.338
cell projection organization GO:0030030 284 0.334
Zebrafish Worm
cellular component morphogenesis GO:0032989 336 0.313
Zebrafish Worm
regulation of neuron projection development GO:0010975 40 0.287
Zebrafish
regulation of macromolecule biosynthetic process GO:0010556 225 0.286
sensory organ development GO:0007423 393 0.279
sympathetic ganglion development GO:0061549 2 0.276
positive regulation of cellular process GO:0048522 201 0.275
establishment of localization GO:0051234 244 0.259
gene expression GO:0010467 252 0.255
rhombomere boundary formation GO:0021654 10 0.251
Zebrafish
regulation of signal transduction GO:0009966 225 0.250
locomotion GO:0040011 313 0.248
cell part morphogenesis GO:0032990 246 0.244
Zebrafish Worm
signal transduction GO:0007165 455 0.241
Human Mouse
angiogenesis GO:0001525 158 0.238
Human Mouse
regulation of metabolic process GO:0019222 359 0.224
cell morphogenesis involved in differentiation GO:0000904 195 0.208
Zebrafish Worm
heterocycle metabolic process GO:0046483 290 0.204
protein import into nucleus GO:0006606 3 0.201
vasculogenesis GO:0001570 41 0.194
enzyme linked receptor protein signaling pathway GO:0007167 106 0.193
Human Mouse
macromolecule biosynthetic process GO:0009059 227 0.190
rhombomere morphogenesis GO:0021593 17 0.190
Zebrafish
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.186
epithelial cell differentiation GO:0030855 116 0.185
cellular response to growth factor stimulus GO:0071363 39 0.184
anterior posterior pattern specification GO:0009952 152 0.184
Zebrafish
camera type eye development GO:0043010 222 0.181
regulation of erk1 and erk2 cascade GO:0070372 4 0.175
eye field cell fate commitment involved in camera type eye formation GO:0060898 3 0.173
cellular nitrogen compound metabolic process GO:0034641 290 0.171
embryo development ending in birth or egg hatching GO:0009792 271 0.169
Worm
single organism transport GO:0044765 206 0.169
mesodermal cell differentiation GO:0048333 21 0.168
positive regulation of biological process GO:0048518 253 0.165
cellular protein modification process GO:0006464 100 0.164
Human Worm
neurological system process GO:0050877 62 0.164
nucleic acid templated transcription GO:0097659 181 0.161
positive regulation of metabolic process GO:0009893 108 0.161
stem cell proliferation GO:0072089 4 0.160
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 42 0.159
Human Mouse
radial glial cell differentiation GO:0060019 2 0.158
regulation of locomotion GO:0040012 55 0.157
negative regulation of collateral sprouting of intact axon in response to injury GO:0048685 2 0.148
Zebrafish
primary neural tube formation GO:0014020 1 0.147
cellular macromolecule metabolic process GO:0044260 391 0.145
Human Worm
regulation of cell communication GO:0010646 232 0.145
brain development GO:0007420 293 0.140
Zebrafish Fly
cell proliferation GO:0008283 80 0.140
generation of neurons GO:0048699 385 0.139
Zebrafish Worm
response to growth factor GO:0070848 39 0.139
regulation of gene expression GO:0010468 265 0.136
regulation of anatomical structure morphogenesis GO:0022603 130 0.134
Zebrafish
single organism localization GO:1902578 225 0.130
digestive tract morphogenesis GO:0048546 231 0.126
regulation of response to stimulus GO:0048583 269 0.125
Zebrafish
establishment of localization in cell GO:0051649 77 0.125
hematopoietic or lymphoid organ development GO:0048534 191 0.125
rna metabolic process GO:0016070 219 0.124
establishment of protein localization to organelle GO:0072594 4 0.123
tube morphogenesis GO:0035239 349 0.123
endocrine system development GO:0035270 65 0.122
regulation of angiogenesis GO:0045765 26 0.121
patterning of blood vessels GO:0001569 15 0.121
phosphorus metabolic process GO:0006793 109 0.120
Human Worm
regulation of cellular metabolic process GO:0031323 320 0.118
artery morphogenesis GO:0048844 14 0.118
immune system process GO:0002376 241 0.117
Fly
system process GO:0003008 185 0.116
neuron development GO:0048666 262 0.114
Zebrafish Worm
single organism nuclear import GO:1902593 3 0.114
regulation of cell proliferation GO:0042127 37 0.114
regulation of intracellular protein transport GO:0033157 3 0.110
rhombomere 4 development GO:0021570 5 0.108
regulation of stem cell proliferation GO:0072091 2 0.101
nucleobase containing compound biosynthetic process GO:0034654 205 0.101
regulation of cellular biosynthetic process GO:0031326 245 0.100
epithelial cell morphogenesis GO:0003382 2 0.099
rna biosynthetic process GO:0032774 181 0.096
intracellular signal transduction GO:0035556 85 0.095
regulation of protein modification by small protein conjugation or removal GO:1903320 3 0.094
protein metabolic process GO:0019538 183 0.092
Human Worm
regulation of primary metabolic process GO:0080090 311 0.091
regulation of rna biosynthetic process GO:2001141 213 0.090
death GO:0016265 121 0.089
regulation of cell death GO:0010941 103 0.089
neuroblast proliferation GO:0007405 2 0.087
regulation of protein localization to nucleus GO:1900180 2 0.087
negative regulation of neuron projection regeneration GO:0070571 4 0.087
Zebrafish
cellular response to chemical stimulus GO:0070887 157 0.087
regulation of cellular response to growth factor stimulus GO:0090287 35 0.086
cell substrate adhesion GO:0031589 4 0.085
regulation of protein transport GO:0051223 3 0.085
cellular component biogenesis GO:0044085 178 0.085
negative regulation of macromolecule metabolic process GO:0010605 76 0.084
larval development GO:0002164 2 0.083
spinal cord radial glial cell differentiation GO:0021531 2 0.083
single organism metabolic process GO:0044710 217 0.083
Fly
negative regulation of collateral sprouting GO:0048671 2 0.080
Zebrafish
organic cyclic compound metabolic process GO:1901360 301 0.079
Fly
positive regulation of transport GO:0051050 2 0.079
protein modification process GO:0036211 100 0.078
Human Worm
head development GO:0060322 303 0.078
Zebrafish Fly
optic placode formation involved in camera type eye formation GO:0046619 3 0.078
protein secretion GO:0009306 1 0.077
heart development GO:0007507 313 0.077
Mouse
embryonic skeletal system morphogenesis GO:0048704 93 0.077
regulation of protein targeting GO:1903533 2 0.075
regulation of cell projection organization GO:0031344 44 0.074
Zebrafish
positive regulation of macromolecule metabolic process GO:0010604 93 0.074
negative regulation of cellular macromolecule biosynthetic process GO:2000113 48 0.074
sensory neuron axon guidance GO:0097374 3 0.074
notch signaling pathway GO:0007219 35 0.073
response to stress GO:0006950 263 0.073
Zebrafish Fly
homeostatic process GO:0042592 142 0.073
organic substance biosynthetic process GO:1901576 289 0.072
cell cycle GO:0007049 93 0.071
negative regulation of axon guidance GO:1902668 1 0.071
regulation of developmental process GO:0050793 247 0.068
Zebrafish
cellular localization GO:0051641 97 0.068
anatomical structure arrangement GO:0048532 2 0.067
transport GO:0006810 220 0.067
mesoderm development GO:0007498 88 0.067
regulation of multicellular organismal process GO:0051239 277 0.066
Zebrafish Worm
oligodendrocyte differentiation GO:0048709 23 0.065
negative regulation of developmental process GO:0051093 65 0.064
Zebrafish
synaptic target recognition GO:0008039 1 0.064
chemotaxis GO:0006935 104 0.063
Worm
regulation of ion transmembrane transporter activity GO:0032412 2 0.062
negative regulation of striated muscle cell differentiation GO:0051154 1 0.061
regulation of meiotic cell cycle GO:0051445 1 0.061
regulation of nucleic acid templated transcription GO:1903506 213 0.061
neuron projection guidance GO:0097485 86 0.061
Worm
selective angioblast sprouting GO:0035474 5 0.060
segmentation GO:0035282 97 0.060
regulation of biosynthetic process GO:0009889 250 0.060
sprouting angiogenesis GO:0002040 53 0.060
Human
protein targeting to nucleus GO:0044744 3 0.059
modification dependent protein catabolic process GO:0019941 3 0.058
cellular response to stress GO:0033554 62 0.058
Zebrafish
positive regulation of striated muscle tissue development GO:0045844 1 0.058
positive regulation of stem cell proliferation GO:2000648 1 0.057
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.057
Zebrafish Worm
negative regulation of cellular process GO:0048523 283 0.055
Zebrafish
eye morphogenesis GO:0048592 144 0.055
stem cell differentiation GO:0048863 117 0.055
regulation of neuron projection regeneration GO:0070570 7 0.055
Zebrafish
response to external stimulus GO:0009605 264 0.054
Zebrafish Worm
regulation of vasculature development GO:1901342 33 0.054
calcium ion transport GO:0006816 18 0.053
protein localization GO:0008104 40 0.053
positive regulation of developmental process GO:0051094 50 0.053
mesoderm formation GO:0001707 43 0.053
regulation of nitrogen compound metabolic process GO:0051171 251 0.053
negative regulation of metabolic process GO:0009892 86 0.053
negative regulation of reproductive process GO:2000242 3 0.053
Worm
anterior posterior axon guidance GO:0033564 5 0.053
protein localization to nucleus GO:0034504 3 0.053
regulation of intracellular signal transduction GO:1902531 57 0.052
dorsal ventral pattern formation GO:0009953 125 0.052
gastrulation GO:0007369 208 0.052
peptidyl serine phosphorylation GO:0018105 1 0.051
regulation of programmed cell death GO:0043067 101 0.051
regulation of vesicle mediated transport GO:0060627 9 0.051
regulation of transcription dna templated GO:0006355 213 0.050
sensory organ morphogenesis GO:0090596 200 0.050
positive regulation of cell cycle GO:0045787 3 0.049
biological adhesion GO:0022610 40 0.049
Human
organic cyclic compound biosynthetic process GO:1901362 223 0.048
chordate embryonic development GO:0043009 271 0.048
facial nerve development GO:0021561 3 0.047
axonogenesis GO:0007409 152 0.047
Zebrafish Worm
response to organic cyclic compound GO:0014070 51 0.047
regulation of signaling GO:0023051 235 0.046
response to endogenous stimulus GO:0009719 83 0.046
negative regulation of macromolecule biosynthetic process GO:0010558 48 0.046
mesoderm morphogenesis GO:0048332 51 0.045
axon development GO:0061564 166 0.045
Zebrafish Worm
aging GO:0007568 2 0.044
positive regulation of mesenchymal cell proliferation GO:0002053 1 0.044
negative regulation of protein transport GO:0051224 3 0.044
pons development GO:0021548 11 0.043
regulation of cellular component movement GO:0051270 55 0.043
positive regulation of neural precursor cell proliferation GO:2000179 1 0.043
optic placode formation GO:0001743 4 0.042
macromolecule localization GO:0033036 54 0.042
negative regulation of nitrogen compound metabolic process GO:0051172 59 0.042
regulation of glial cell differentiation GO:0045685 4 0.042
innervation GO:0060384 3 0.042
positive regulation of cellular amine metabolic process GO:0033240 0 0.042
cellular amine metabolic process GO:0044106 2 0.042
regulation of cell development GO:0060284 100 0.041
Zebrafish
artery development GO:0060840 22 0.041
negative regulation of cellular metabolic process GO:0031324 77 0.041
negative regulation of biological process GO:0048519 304 0.041
Zebrafish Worm
cell cycle process GO:0022402 53 0.041
amine metabolic process GO:0009308 2 0.040
epidermis development GO:0008544 48 0.040
regulation of gastrulation GO:0010470 24 0.040
facial nucleus development GO:0021754 7 0.040
mesodermal cell fate specification GO:0007501 12 0.040
trigeminal motor nucleus development GO:0021731 2 0.040
regulation of cell migration GO:0030334 40 0.039
mitotic cell cycle GO:0000278 64 0.038
behavior GO:0007610 74 0.038
endocardial cushion formation GO:0003272 2 0.038
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.038
negative chemotaxis GO:0050919 1 0.037
macromolecule modification GO:0043412 111 0.037
Human Worm
nephron tubule epithelial cell differentiation GO:0072160 1 0.037
oxoacid metabolic process GO:0043436 31 0.037
negative regulation of stem cell differentiation GO:2000737 2 0.036
negative regulation of nucleic acid templated transcription GO:1903507 45 0.036
regulation of cell differentiation GO:0045595 142 0.036
Zebrafish
positive regulation of endothelial cell differentiation GO:0045603 2 0.036
embryonic viscerocranium morphogenesis GO:0048703 52 0.035
mesodermal cell migration GO:0008078 12 0.035
heterocycle biosynthetic process GO:0018130 215 0.035
forebrain cell migration GO:0021885 1 0.035
nitrogen compound metabolic process GO:0006807 319 0.035
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.034
regulation of macromolecule metabolic process GO:0060255 317 0.034
hemopoiesis GO:0030097 183 0.034
regulation of establishment of protein localization GO:0070201 4 0.034
positive regulation of response to stimulus GO:0048584 80 0.034
positive regulation of locomotion GO:0040017 14 0.033
response to organic substance GO:0010033 153 0.033
cell fate commitment GO:0045165 99 0.033
neuroblast differentiation GO:0014016 1 0.033
regulation of oligodendrocyte differentiation GO:0048713 1 0.032
negative regulation of cellular biosynthetic process GO:0031327 55 0.032
regulation of cellular amino acid metabolic process GO:0006521 0 0.032
multicellular organism growth GO:0035264 4 0.031
cellular nitrogen compound biosynthetic process GO:0044271 218 0.031
response to wounding GO:0009611 116 0.031
Zebrafish
tube closure GO:0060606 1 0.031
regulation of cell motility GO:2000145 46 0.031
regulation of multicellular organismal development GO:2000026 223 0.031
Zebrafish
multi organism process GO:0051704 134 0.031
Worm
positive regulation of mesoderm development GO:2000382 1 0.031
cellular biosynthetic process GO:0044249 286 0.030
nucleocytoplasmic transport GO:0006913 4 0.030
cellular protein localization GO:0034613 20 0.030
negative regulation of apoptotic process GO:0043066 55 0.030
nuclear transport GO:0051169 4 0.030
skeletal system morphogenesis GO:0048705 102 0.030
developmental cell growth GO:0048588 52 0.030
Zebrafish
negative regulation of axon extension involved in axon guidance GO:0048843 1 0.030
wnt signaling pathway planar cell polarity pathway GO:0060071 4 0.030
formation of primary germ layer GO:0001704 62 0.030
positive regulation of gtp catabolic process GO:0033126 1 0.029
neural tube development GO:0021915 62 0.029
trabecula formation GO:0060343 2 0.029
regionalization GO:0003002 274 0.029
Zebrafish
determination of bilateral symmetry GO:0009855 204 0.028
negative regulation of cell migration GO:0030336 17 0.028
cardiac atrium morphogenesis GO:0003209 2 0.028
taxis GO:0042330 109 0.028
Worm
cardiac cell fate commitment GO:0060911 1 0.028
phosphorylation GO:0016310 69 0.028
Human Worm
positive regulation of signal transduction GO:0009967 56 0.028
lateral line development GO:0048882 66 0.028
protein import GO:0017038 3 0.027
transcription from rna polymerase ii promoter GO:0006366 80 0.027
metal ion transport GO:0030001 58 0.027
regulation of mesodermal cell fate specification GO:0042661 9 0.027
epithelium migration GO:0090132 25 0.026
Human
endodermal cell fate determination GO:0007493 2 0.026
regulation of cellular ketone metabolic process GO:0010565 7 0.026
embryonic skeletal joint development GO:0072498 3 0.026
extrinsic apoptotic signaling pathway via death domain receptors GO:0008625 1 0.026
regulation of transmembrane transport GO:0034762 18 0.026
positive regulation of multicellular organismal process GO:0051240 52 0.026
erk1 and erk2 cascade GO:0070371 4 0.025
epithelial tube morphogenesis GO:0060562 148 0.025
negative regulation of gene expression GO:0010629 65 0.025
glial cell differentiation GO:0010001 42 0.025
heart morphogenesis GO:0003007 156 0.025
Mouse
morphogenesis of an epithelium GO:0002009 333 0.025
gliogenesis GO:0042063 45 0.025
nuclear import GO:0051170 3 0.024
cellular response to organic substance GO:0071310 105 0.024
organelle organization GO:0006996 227 0.024
cell substrate junction assembly GO:0007044 2 0.024
muscle cell fate determination GO:0007521 1 0.024
cation transport GO:0006812 81 0.024
positive regulation of cell death GO:0010942 29 0.024
negative regulation of transcription dna templated GO:0045892 45 0.024
camera type eye morphogenesis GO:0048593 108 0.023
regulation of mesenchymal cell proliferation GO:0010464 1 0.023
locomotory behavior GO:0007626 34 0.023
regulation of organ growth GO:0046620 3 0.023
motor neuron axon guidance GO:0008045 23 0.023
negative regulation of signal transduction GO:0009968 94 0.023
regulation of embryonic development GO:0045995 47 0.023
axon regeneration GO:0031103 14 0.023
Zebrafish
synaptic transmission GO:0007268 35 0.023
negative regulation of cell death GO:0060548 60 0.023
cellular ketone metabolic process GO:0042180 11 0.023
regulation of inner ear receptor cell differentiation GO:2000980 1 0.023
cellular protein metabolic process GO:0044267 129 0.023
Human Worm
regulation of epithelial cell proliferation GO:0050678 3 0.023
regulation of wnt signaling pathway GO:0030111 53 0.023
regulation of multicellular organism growth GO:0040014 4 0.022
regulation of response to external stimulus GO:0032101 31 0.022
Zebrafish
negative regulation of response to stimulus GO:0048585 104 0.022
Zebrafish
muscle organ development GO:0007517 101 0.022
regulation of cellular response to stress GO:0080135 20 0.022
Zebrafish
nucleic acid metabolic process GO:0090304 244 0.022
regulation of protein import into nucleus GO:0042306 2 0.021
glomerulus vasculature development GO:0072012 2 0.021
organ regeneration GO:0031100 1 0.021
regulation of cellular amine metabolic process GO:0033238 0 0.021
apoptotic process GO:0006915 116 0.021
gland development GO:0048732 143 0.021
single organism cellular localization GO:1902580 46 0.021
regulation of response to drug GO:2001023 1 0.021
mapk cascade GO:0000165 18 0.021
nucleobase containing compound metabolic process GO:0006139 274 0.021
regeneration GO:0031099 91 0.021
Zebrafish
rhombomere development GO:0021546 19 0.021
Zebrafish
homeostasis of number of cells GO:0048872 62 0.020
regulation of localization GO:0032879 104 0.020
lateral inhibition GO:0046331 1 0.020
regulation of endodermal cell differentiation GO:1903224 15 0.020
negative regulation of angiogenesis GO:0016525 7 0.020
neuron projection regeneration GO:0031102 16 0.020
Zebrafish
regulation of cell shape GO:0008360 1 0.019
cartilage development GO:0051216 96 0.019
single organism intracellular transport GO:1902582 25 0.019
negative regulation of biosynthetic process GO:0009890 55 0.019
protein localization to plasma membrane GO:0072659 1 0.019
positive regulation of muscle tissue development GO:1901863 1 0.019
negative regulation of cell development GO:0010721 26 0.019
Zebrafish
brain morphogenesis GO:0048854 18 0.019
positive regulation of erk1 and erk2 cascade GO:0070374 2 0.019
synaptic growth at neuromuscular junction GO:0051124 2 0.019
positive regulation of catabolic process GO:0009896 4 0.019
intracellular transport GO:0046907 32 0.019
ion transmembrane transport GO:0034220 91 0.019
branchiomotor neuron axon guidance GO:0021785 1 0.019
single organism membrane organization GO:0044802 20 0.019
negative regulation of signaling GO:0023057 96 0.019
organonitrogen compound metabolic process GO:1901564 74 0.019
positive regulation of response to external stimulus GO:0032103 9 0.018
cell cell signaling GO:0007267 52 0.018
cellular component assembly GO:0022607 170 0.018
positive regulation of muscle organ development GO:0048636 1 0.018
ameboidal type cell migration GO:0001667 143 0.018
Human
regulation of rna metabolic process GO:0051252 224 0.018
regulation of axon regeneration GO:0048679 7 0.018
Zebrafish
posterior lateral line system development GO:0048915 46 0.018
myeloid cell differentiation GO:0030099 86 0.018
ubiquitin dependent protein catabolic process GO:0006511 3 0.018
embryonic digestive tract morphogenesis GO:0048557 3 0.018
regulation of sodium ion transport GO:0002028 2 0.018
cellular macromolecule biosynthetic process GO:0034645 224 0.018
cell death GO:0008219 121 0.017
regulation of gtpase activity GO:0043087 2 0.017
regulation of growth GO:0040008 42 0.017
Zebrafish
carbohydrate biosynthetic process GO:0016051 1 0.017
regulation of receptor mediated endocytosis GO:0048259 4 0.017
biosynthetic process GO:0009058 294 0.017
development of primary female sexual characteristics GO:0046545 4 0.017
positive regulation of cell communication GO:0010647 56 0.017
neural retina development GO:0003407 49 0.017
blood vessel endothelial cell migration GO:0043534 18 0.017
Human
cell projection morphogenesis GO:0048858 244 0.017
Zebrafish Worm
appendage morphogenesis GO:0035107 56 0.017
ion transport GO:0006811 114 0.016
negative regulation of rna metabolic process GO:0051253 48 0.016
regulation of metal ion transport GO:0010959 4 0.016
female sex differentiation GO:0046660 4 0.016
programmed cell death GO:0012501 119 0.016
skeletal system development GO:0001501 181 0.016
peripheral nervous system neuron differentiation GO:0048934 28 0.016
guanosine containing compound metabolic process GO:1901068 4 0.016
multicellular organismal reproductive process GO:0048609 35 0.016
Worm
primitive hemopoiesis GO:0060215 27 0.016
embryonic limb morphogenesis GO:0030326 2 0.016
endoderm development GO:0007492 49 0.016
collateral sprouting of intact axon in response to injury GO:0048673 2 0.016
Zebrafish
regulation of cell morphogenesis GO:0022604 42 0.015
Zebrafish
regulation of apoptotic process GO:0042981 98 0.015
divalent metal ion transport GO:0070838 20 0.015
trigeminal nerve development GO:0021559 3 0.015
single organism organelle organization GO:1902589 199 0.015
regulation of carbohydrate metabolic process GO:0006109 4 0.015
negative regulation of neurogenesis GO:0050768 20 0.015
Zebrafish
regulation of endodermal cell fate specification GO:0042663 15 0.015
negative regulation of gliogenesis GO:0014014 1 0.015
cell migration involved in sprouting angiogenesis GO:0002042 8 0.015
Human
digestive system development GO:0055123 289 0.015
positive regulation of signaling GO:0023056 56 0.015
tissue migration GO:0090130 37 0.015
Human
modification dependent macromolecule catabolic process GO:0043632 3 0.015
cellular macromolecule localization GO:0070727 21 0.015
regulation of protein ubiquitination GO:0031396 3 0.015
posterior lateral line development GO:0048916 38 0.014
microtubule based process GO:0007017 60 0.014
positive regulation of embryonic development GO:0040019 3 0.014
central nervous system development GO:0007417 387 0.014
Zebrafish Fly
negative regulation of wnt signaling pathway GO:0030178 30 0.014
positive regulation of gene expression GO:0010628 71 0.014
regulation of molecular function GO:0065009 70 0.014
cranial nerve morphogenesis GO:0021602 15 0.014
regulation of protein metabolic process GO:0051246 56 0.014
forebrain anterior posterior pattern specification GO:0021797 3 0.014
cell cycle g1 s phase transition GO:0044843 1 0.014
regulation of cytoplasmic transport GO:1903649 4 0.014
meiotic nuclear division GO:0007126 4 0.014
regulation of neural retina development GO:0061074 2 0.014
regulation of nucleotide catabolic process GO:0030811 2 0.014
regulation of reproductive process GO:2000241 4 0.014
Worm
digestive tract development GO:0048565 265 0.014
non canonical wnt signaling pathway GO:0035567 13 0.014
regulation of cell activation GO:0050865 1 0.013
sensory perception GO:0007600 39 0.013
abducens nerve development GO:0021560 1 0.013
positive regulation of cell activation GO:0050867 1 0.013
negative regulation of rna biosynthetic process GO:1902679 45 0.013
lipid catabolic process GO:0016042 4 0.013
regulation of neural precursor cell proliferation GO:2000177 3 0.013
cellular protein catabolic process GO:0044257 4 0.013
peptidyl threonine phosphorylation GO:0018107 1 0.013
regulation of cellular protein metabolic process GO:0032268 52 0.013
embryonic hemopoiesis GO:0035162 53 0.013
axonogenesis involved in innervation GO:0060385 1 0.013
determination of heart left right asymmetry GO:0061371 117 0.013
female gonad development GO:0008585 4 0.013
regulation of purine nucleotide catabolic process GO:0033121 2 0.013
cell chemotaxis GO:0060326 17 0.013
fin development GO:0033333 77 0.013
developmental growth GO:0048589 166 0.013
Zebrafish
neural keel formation GO:0014025 1 0.013
negative regulation of programmed cell death GO:0043069 58 0.013
connective tissue development GO:0061448 99 0.012
receptor internalization GO:0031623 2 0.012
regulation of mononuclear cell migration GO:0071675 1 0.012
neuron projection morphogenesis GO:0048812 161 0.012
Zebrafish Worm
forebrain development GO:0030900 96 0.012
Zebrafish
myeloid leukocyte differentiation GO:0002573 15 0.012
regulation of bmp signaling pathway GO:0030510 39 0.012
phosphate containing compound metabolic process GO:0006796 108 0.012
Human Worm
negative regulation of epithelial cell proliferation GO:0050680 1 0.012
negative regulation of protein phosphorylation GO:0001933 4 0.012
pancreas development GO:0031016 84 0.012
terpenoid catabolic process GO:0016115 2 0.012
positive regulation of cellular catabolic process GO:0031331 3 0.012
diencephalon morphogenesis GO:0048852 5 0.012
regulation of transporter activity GO:0032409 2 0.012
somite development GO:0061053 96 0.012
bmp signaling pathway GO:0030509 52 0.012
cell migration involved in gastrulation GO:0042074 79 0.012

ephb4a disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
osteochondrodysplasia DOID:2256 0 0.022
bone development disease DOID:0080006 0 0.022
bone disease DOID:0080001 0 0.022
cleidocranial dysplasia DOID:13994 0 0.022
disease of anatomical entity DOID:7 0 0.022
musculoskeletal system disease DOID:17 0 0.022
connective tissue disease DOID:65 0 0.022
orofacial cleft DOID:0050567 0 0.021
physical disorder DOID:0080015 0 0.021
pfeiffer syndrome DOID:14705 0 0.019
acrocephalosyndactylia DOID:12960 0 0.019
dysostosis DOID:1934 0 0.019
synostosis DOID:11971 0 0.019
congenital heart disease DOID:1682 0 0.014
heart septal defect DOID:1681 0 0.014
atrioventricular septal defect DOID:0050651 0 0.014
heart disease DOID:114 0 0.014
cardiovascular system disease DOID:1287 0 0.014
kidney cancer DOID:263 0 0.013
urinary system cancer DOID:3996 0 0.013
cancer DOID:162 0 0.013
disease of cellular proliferation DOID:14566 0 0.013
organ system cancer DOID:0050686 0 0.013
nephroblastoma DOID:2154 0 0.013