Danio rerio

0 known processes

ephb4b

eph receptor B4b

(Aliases: EphB-rtk8,cb417,rtk8)

ephb4b biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
cell surface receptor signaling pathway GO:0007166 325 0.978
Human Mouse
regulation of gene expression GO:0010468 265 0.968
axon development GO:0061564 166 0.956
Zebrafish Worm
larval development GO:0002164 2 0.943
hematopoietic or lymphoid organ development GO:0048534 191 0.911
blood vessel development GO:0001568 246 0.908
Human Zebrafish Mouse
neuron projection development GO:0031175 180 0.893
Zebrafish Worm
heart development GO:0007507 313 0.883
Mouse
ameboidal type cell migration GO:0001667 143 0.836
Human
positive regulation of jun kinase activity GO:0043507 2 0.831
eye field cell fate commitment involved in camera type eye formation GO:0060898 3 0.826
signal transduction GO:0007165 455 0.825
Human Mouse
dorsal ventral pattern formation GO:0009953 125 0.823
regulation of anatomical structure morphogenesis GO:0022603 130 0.804
Zebrafish
nucleic acid metabolic process GO:0090304 244 0.796
mesoderm formation GO:0001707 43 0.790
cell fate commitment GO:0045165 99 0.774
tube morphogenesis GO:0035239 349 0.770
nitrogen compound metabolic process GO:0006807 319 0.760
optic placode formation involved in camera type eye formation GO:0046619 3 0.757
sensory organ morphogenesis GO:0090596 200 0.756
determination of left right symmetry GO:0007368 179 0.739
regulation of metabolic process GO:0019222 359 0.739
cell morphogenesis involved in differentiation GO:0000904 195 0.735
Zebrafish Worm
neuron differentiation GO:0030182 353 0.733
Zebrafish Worm
heart morphogenesis GO:0003007 156 0.731
Mouse
cellular macromolecule biosynthetic process GO:0034645 224 0.720
blood vessel morphogenesis GO:0048514 216 0.719
Human Zebrafish Mouse
regionalization GO:0003002 274 0.714
Zebrafish
embryonic heart tube development GO:0035050 133 0.713
developmental process involved in reproduction GO:0003006 27 0.708
Worm
axon guidance GO:0007411 86 0.706
Worm
macromolecule biosynthetic process GO:0009059 227 0.705
cellular component morphogenesis GO:0032989 336 0.700
Zebrafish Worm
eye development GO:0001654 277 0.683
determination of bilateral symmetry GO:0009855 204 0.681
sensory organ development GO:0007423 393 0.679
regulation of epithelial cell proliferation GO:0050678 3 0.667
digestive tract development GO:0048565 265 0.666
gastrulation GO:0007369 208 0.659
neuron projection guidance GO:0097485 86 0.658
Worm
regulation of wnt signaling pathway GO:0030111 53 0.658
negative regulation of neuron projection regeneration GO:0070571 4 0.658
Zebrafish
cellular aromatic compound metabolic process GO:0006725 295 0.654
Fly
wnt signaling pathway GO:0016055 80 0.652
negative regulation of cellular process GO:0048523 283 0.649
Zebrafish
regulation of macromolecule biosynthetic process GO:0010556 225 0.641
digestive system development GO:0055123 289 0.636
neuron projection extension GO:1990138 45 0.631
Zebrafish
ectodermal placode formation GO:0060788 26 0.625
cell morphogenesis GO:0000902 289 0.618
Zebrafish Worm
cell projection morphogenesis GO:0048858 244 0.612
Zebrafish Worm
formation of primary germ layer GO:0001704 62 0.610
digestive tract morphogenesis GO:0048546 231 0.604
gene expression GO:0010467 252 0.604
cell migration GO:0016477 237 0.589
Human Zebrafish
regulation of macromolecule metabolic process GO:0060255 317 0.578
cell projection organization GO:0030030 284 0.578
Zebrafish Worm
immune system development GO:0002520 191 0.569
enzyme linked receptor protein signaling pathway GO:0007167 106 0.564
Human Mouse
neuroblast proliferation GO:0007405 2 0.559
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.558
Zebrafish Worm
regulation of canonical wnt signaling pathway GO:0060828 34 0.548
convergent extension involved in gastrulation GO:0060027 71 0.547
cell fate commitment involved in formation of primary germ layer GO:0060795 26 0.547
organic substance biosynthetic process GO:1901576 289 0.544
stem cell proliferation GO:0072089 4 0.534
cell motility GO:0048870 244 0.533
Human Zebrafish
regulation of developmental process GO:0050793 247 0.531
Zebrafish
determination of heart left right asymmetry GO:0061371 117 0.531
camera type eye development GO:0043010 222 0.530
hindbrain development GO:0030902 91 0.526
Zebrafish
cell migration involved in gastrulation GO:0042074 79 0.522
cellular component biogenesis GO:0044085 178 0.521
organic cyclic compound biosynthetic process GO:1901362 223 0.521
angiogenesis GO:0001525 158 0.520
Human Mouse
regulation of multicellular organismal process GO:0051239 277 0.519
Zebrafish Worm
regulation of cellular response to growth factor stimulus GO:0090287 35 0.515
rna metabolic process GO:0016070 219 0.512
cell part morphogenesis GO:0032990 246 0.497
Zebrafish Worm
pronuclear migration GO:0035046 1 0.495
hemopoiesis GO:0030097 183 0.492
regulation of response to stimulus GO:0048583 269 0.491
Zebrafish
gland development GO:0048732 143 0.484
retina development in camera type eye GO:0060041 146 0.482
biosynthetic process GO:0009058 294 0.475
cellular component assembly GO:0022607 170 0.471
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.461
rna biosynthetic process GO:0032774 181 0.458
regulation of primary metabolic process GO:0080090 311 0.453
regulation of cell differentiation GO:0045595 142 0.450
Zebrafish
optic placode formation GO:0001743 4 0.447
ectodermal placode development GO:0071696 37 0.442
cellular biosynthetic process GO:0044249 286 0.440
generation of neurons GO:0048699 385 0.438
Zebrafish Worm
head development GO:0060322 303 0.438
Zebrafish Fly
fin morphogenesis GO:0033334 53 0.435
meiotic nuclear division GO:0007126 4 0.428
negative regulation of biological process GO:0048519 304 0.421
Zebrafish Worm
neuron development GO:0048666 262 0.420
Zebrafish Worm
regulation of cellular metabolic process GO:0031323 320 0.414
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 42 0.410
Human Mouse
nucleic acid templated transcription GO:0097659 181 0.401
nuclear migration GO:0007097 3 0.400
cell cycle process GO:0022402 53 0.398
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 50 0.395
canonical wnt signaling pathway GO:0060070 48 0.388
regulation of fibroblast growth factor receptor signaling pathway GO:0040036 20 0.385
mesodermal cell differentiation GO:0048333 21 0.385
positive regulation of stress activated protein kinase signaling cascade GO:0070304 3 0.380
developmental growth GO:0048589 166 0.378
Zebrafish
specification of symmetry GO:0009799 204 0.374
heterocycle metabolic process GO:0046483 290 0.373
response to growth factor GO:0070848 39 0.359
dorsal convergence GO:0060030 14 0.351
negative regulation of smoothened signaling pathway GO:0045879 6 0.350
regulation of cell morphogenesis GO:0022604 42 0.350
Zebrafish
central nervous system development GO:0007417 387 0.342
Zebrafish Fly
regulation of collateral sprouting of intact axon in response to injury GO:0048683 2 0.340
Zebrafish
otic vesicle formation GO:0030916 27 0.334
negative regulation of collateral sprouting of intact axon in response to injury GO:0048685 2 0.334
Zebrafish
forebrain generation of neurons GO:0021872 14 0.329
mesoderm morphogenesis GO:0048332 51 0.329
cellular component movement GO:0006928 335 0.327
Human Zebrafish Worm
cellular macromolecule metabolic process GO:0044260 391 0.327
Human Worm
regulation of neurogenesis GO:0050767 87 0.324
Zebrafish
aromatic compound biosynthetic process GO:0019438 217 0.324
mesodermal cell migration GO:0008078 12 0.323
convergent extension GO:0060026 118 0.323
Zebrafish
positive regulation of stress activated mapk cascade GO:0032874 3 0.320
organic cyclic compound metabolic process GO:1901360 301 0.316
Fly
regulation of cellular biosynthetic process GO:0031326 245 0.315
cell surface receptor signaling pathway involved in heart development GO:0061311 20 0.311
positive regulation of cell cycle GO:0045787 3 0.303
heterocycle biosynthetic process GO:0018130 215 0.301
positive regulation of oocyte development GO:0060282 1 0.299
chemotaxis GO:0006935 104 0.297
Worm
lateral inhibition GO:0046331 1 0.295
response to stress GO:0006950 263 0.294
Zebrafish Fly
regulation of transcription from rna polymerase ii promoter involved in determination of left right symmetry GO:1900094 17 0.294
regulation of endodermal cell fate specification GO:0042663 15 0.292
regulation of signal transduction GO:0009966 225 0.292
regulation of nucleic acid templated transcription GO:1903506 213 0.291
regulation of gastrulation GO:0010470 24 0.287
regulation of biosynthetic process GO:0009889 250 0.284
neural tube development GO:0021915 62 0.284
epithelial tube morphogenesis GO:0060562 148 0.283
dorsal ventral axis specification GO:0009950 14 0.282
positive regulation of map kinase activity GO:0043406 3 0.280
cellular nitrogen compound metabolic process GO:0034641 290 0.279
regulation of cell morphogenesis involved in differentiation GO:0010769 38 0.268
Zebrafish
eye morphogenesis GO:0048592 144 0.265
regulation of nitrogen compound metabolic process GO:0051171 251 0.265
regulation of transcription from rna polymerase ii promoter GO:0006357 114 0.265
endocrine pancreas development GO:0031018 27 0.265
positive regulation of jnk cascade GO:0046330 3 0.265
forebrain neuron differentiation GO:0021879 14 0.264
negative regulation of axon guidance GO:1902668 1 0.264
synaptic target recognition GO:0008039 1 0.264
regulation of synapse organization GO:0050807 3 0.263
angioblast cell migration involved in selective angioblast sprouting GO:0035475 4 0.261
Zebrafish
regulation of signaling GO:0023051 235 0.255
heart looping GO:0001947 94 0.254
negative regulation of canonical wnt signaling pathway GO:0090090 21 0.252
organelle organization GO:0006996 227 0.245
positive regulation of metabolic process GO:0009893 108 0.242
response to wounding GO:0009611 116 0.238
Zebrafish
mesoderm development GO:0007498 88 0.237
transcription dna templated GO:0006351 181 0.235
determination of ventral identity GO:0048264 21 0.234
chordate embryonic development GO:0043009 271 0.232
muscle cell migration GO:0014812 4 0.232
ectodermal placode morphogenesis GO:0071697 32 0.232
regulation of multicellular organismal development GO:2000026 223 0.228
Zebrafish
axon extension GO:0048675 45 0.227
Zebrafish
negative regulation of collateral sprouting GO:0048671 2 0.226
Zebrafish
response to external stimulus GO:0009605 264 0.223
Zebrafish Worm
axonogenesis GO:0007409 152 0.220
Zebrafish Worm
maintenance of location GO:0051235 4 0.219
otic vesicle morphogenesis GO:0071600 34 0.218
olfactory lobe development GO:0021988 4 0.217
bmp signaling pathway GO:0030509 52 0.217
retinoic acid biosynthetic process GO:0002138 6 0.217
brain development GO:0007420 293 0.217
Zebrafish Fly
axis specification GO:0009798 43 0.213
embryonic pattern specification GO:0009880 44 0.213
neural plate regionalization GO:0060897 10 0.210
growth GO:0040007 174 0.209
Zebrafish
neural plate pattern specification GO:0060896 12 0.206
embryonic eye morphogenesis GO:0048048 30 0.206
protein metabolic process GO:0019538 183 0.205
Human Worm
regulation of meiotic cell cycle GO:0051445 1 0.203
cell cell signaling involved in cell fate commitment GO:0045168 12 0.201
vasculature development GO:0001944 278 0.200
Human Zebrafish Mouse
artery morphogenesis GO:0048844 14 0.198
taxis GO:0042330 109 0.197
Worm
neuron projection morphogenesis GO:0048812 161 0.196
Zebrafish Worm
synaptic growth at neuromuscular junction GO:0051124 2 0.196
regulation of bmp signaling pathway involved in heart jogging GO:2000223 12 0.192
wound healing GO:0042060 90 0.192
localization of cell GO:0051674 244 0.192
Human Zebrafish
myeloid cell differentiation GO:0030099 86 0.191
negative chemotaxis GO:0050919 1 0.190
regulation of cellular component organization GO:0051128 86 0.189
Zebrafish
embryonic organ development GO:0048568 381 0.188
negative regulation of axon extension GO:0030517 7 0.186
Zebrafish
protein complex subunit organization GO:0071822 46 0.184
negative regulation of signal transduction GO:0009968 94 0.184
cell fate specification GO:0001708 68 0.184
positive regulation of macromolecule metabolic process GO:0010604 93 0.183
biological adhesion GO:0022610 40 0.183
Human
negative regulation of cell communication GO:0010648 96 0.180
nucleobase containing compound metabolic process GO:0006139 274 0.180
motor neuron axon guidance GO:0008045 23 0.177
forebrain regionalization GO:0021871 4 0.176
regulation of smoothened signaling pathway GO:0008589 18 0.175
embryo development ending in birth or egg hatching GO:0009792 271 0.173
Worm
positive regulation of cellular process GO:0048522 201 0.173
positive regulation of canonical wnt signaling pathway GO:0090263 4 0.172
appendage morphogenesis GO:0035107 56 0.172
multicellular organism growth GO:0035264 4 0.169
embryonic camera type eye development GO:0031076 29 0.166
negative regulation of developmental process GO:0051093 65 0.165
Zebrafish
pancreas development GO:0031016 84 0.162
mapk cascade GO:0000165 18 0.161
endoderm formation GO:0001706 29 0.158
sprouting angiogenesis GO:0002040 53 0.157
Human
regulation of bmp signaling pathway GO:0030510 39 0.157
negative regulation of gene expression GO:0010629 65 0.156
mesodermal cell fate commitment GO:0001710 14 0.156
regulation of cell growth GO:0001558 29 0.156
Zebrafish
actin cytoskeleton organization GO:0030036 63 0.151
non canonical wnt signaling pathway GO:0035567 13 0.151
regulation of nervous system development GO:0051960 90 0.148
Zebrafish
bmp signaling pathway involved in heart development GO:0061312 15 0.148
positive regulation of biological process GO:0048518 253 0.146
regulation of rna metabolic process GO:0051252 224 0.145
transcription from rna polymerase ii promoter GO:0006366 80 0.143
pectoral fin morphogenesis GO:0035138 29 0.143
muscle cell differentiation GO:0042692 139 0.143
hindbrain morphogenesis GO:0021575 22 0.142
embryonic heart tube morphogenesis GO:0003143 108 0.142
central nervous system neuron differentiation GO:0021953 74 0.140
regeneration GO:0031099 91 0.140
Zebrafish
body morphogenesis GO:0010171 16 0.139
Worm
lipid storage GO:0019915 1 0.138
mitotic cell cycle GO:0000278 64 0.137
camera type eye morphogenesis GO:0048593 108 0.137
cell substrate adhesion GO:0031589 4 0.137
somite development GO:0061053 96 0.137
epithelial cell development GO:0002064 42 0.135
phosphorylation GO:0016310 69 0.133
Human Worm
stem cell maintenance GO:0019827 4 0.132
establishment of spindle orientation GO:0051294 10 0.131
axon regeneration GO:0031103 14 0.131
Zebrafish
cytoskeleton organization GO:0007010 96 0.130
immune system process GO:0002376 241 0.128
Fly
cell adhesion GO:0007155 40 0.128
Human
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 68 0.127
negative regulation of macromolecule metabolic process GO:0010605 76 0.127
olfactory bulb development GO:0021772 4 0.127
regulation of axon extension GO:0030516 24 0.127
Zebrafish
regulation of rna biosynthetic process GO:2001141 213 0.126
negative regulation of nervous system development GO:0051961 22 0.125
Zebrafish
hard palate development GO:0060022 4 0.124
neural nucleus development GO:0048857 15 0.123
negative regulation of response to stimulus GO:0048585 104 0.123
Zebrafish
ear morphogenesis GO:0042471 64 0.121
negative regulation of metabolic process GO:0009892 86 0.121
notch signaling pathway GO:0007219 35 0.121
positive regulation of signal transduction GO:0009967 56 0.120
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.120
protein stabilization GO:0050821 2 0.120
regulation of axonogenesis GO:0050770 32 0.118
Zebrafish
regulation of mrna processing GO:0050684 3 0.118
endoderm development GO:0007492 49 0.118
regulation of cell communication GO:0010646 232 0.116
cellular nitrogen compound biosynthetic process GO:0044271 218 0.116
endodermal cell fate specification GO:0001714 17 0.116
regulation of synapse assembly GO:0051963 3 0.116
negative regulation of axon extension involved in axon guidance GO:0048843 1 0.115
cell recognition GO:0008037 19 0.115
Zebrafish
regulation of transcription dna templated GO:0006355 213 0.114
otic placode formation GO:0043049 23 0.113
embryonic skeletal system morphogenesis GO:0048704 93 0.111
somitogenesis GO:0001756 87 0.110
smoothened signaling pathway GO:0007224 30 0.110
locomotion GO:0040011 313 0.107
Human Zebrafish Worm
nucleobase containing compound biosynthetic process GO:0034654 205 0.107
mesodermal cell fate specification GO:0007501 12 0.106
liver development GO:0001889 96 0.106
regulation of neuron projection development GO:0010975 40 0.105
Zebrafish
neuron recognition GO:0008038 18 0.105
diencephalon development GO:0021536 58 0.105
radial glial cell differentiation GO:0060019 2 0.104
positive regulation of rna metabolic process GO:0051254 59 0.104
somatic stem cell maintenance GO:0035019 1 0.104
negative regulation of anterior neural cell fate commitment of the neural plate GO:0022001 1 0.102
anterior posterior axon guidance GO:0033564 5 0.101
neuron projection regeneration GO:0031102 16 0.099
Zebrafish
wnt signaling pathway involved in digestive tract morphogenesis GO:0044333 4 0.099
gastrulation with mouth forming second GO:0001702 44 0.098
epithelium regeneration GO:1990399 14 0.096
single organism organelle organization GO:1902589 199 0.096
cell fate commitment involved in pattern specification GO:0060581 6 0.095
morphogenesis of an epithelium GO:0002009 333 0.095
Zebrafish Worm
cell growth GO:0016049 57 0.094
Zebrafish
forebrain anterior posterior pattern specification GO:0021797 3 0.094
regulation of stem cell differentiation GO:2000736 4 0.094
single organism cell adhesion GO:0098602 29 0.094
positive regulation of nucleoside metabolic process GO:0045979 1 0.093
response to chemical GO:0042221 320 0.093
Worm
embryonic hemopoiesis GO:0035162 53 0.092
monocarboxylic acid catabolic process GO:0072329 3 0.092
positive regulation of developmental process GO:0051094 50 0.091
synapse organization GO:0050808 21 0.091
regulation of gtp catabolic process GO:0033124 2 0.090
cellular process involved in reproduction in multicellular organism GO:0022412 28 0.090
Worm
cell cycle GO:0007049 93 0.090
anterior posterior pattern specification GO:0009952 152 0.089
Zebrafish
inner ear morphogenesis GO:0042472 63 0.089
response to other organism GO:0051707 97 0.089
regulation of transcription from rna polymerase ii promoter involved in heart development GO:1901213 15 0.089
aging GO:0007568 2 0.089
single organism reproductive process GO:0044702 40 0.088
Worm
negative regulation of anterior neural cell fate commitment of the neural plate by wnt signaling pathway GO:0022002 1 0.087
cell migration involved in heart development GO:0060973 22 0.086
fin development GO:0033333 77 0.085
female meiotic division GO:0007143 2 0.084
striated muscle cell differentiation GO:0051146 129 0.084
spindle localization GO:0051653 12 0.084
positive regulation of cellular component biogenesis GO:0044089 3 0.084
regulation of embryonic development GO:0045995 47 0.084
embryonic camera type eye formation GO:0060900 10 0.083
macromolecular complex subunit organization GO:0043933 74 0.083
embryonic pectoral fin morphogenesis GO:0035118 24 0.082
tissue regeneration GO:0042246 74 0.082
metencephalon development GO:0022037 27 0.081
cartilage development GO:0051216 96 0.081
pectoral fin development GO:0033339 50 0.080
endodermal cell fate commitment GO:0001711 18 0.080
embryonic camera type eye morphogenesis GO:0048596 19 0.080
retina morphogenesis in camera type eye GO:0060042 79 0.080
photoreceptor cell fate commitment GO:0046552 1 0.078
cellular response to growth factor stimulus GO:0071363 39 0.078
negative regulation of rna metabolic process GO:0051253 48 0.078
epiboly GO:0090504 41 0.076
negative regulation of signaling GO:0023057 96 0.076
striated muscle cell development GO:0055002 108 0.076
organic acid metabolic process GO:0006082 31 0.076
organelle assembly GO:0070925 110 0.076
muscle fiber development GO:0048747 52 0.075
inner ear receptor cell fate commitment GO:0060120 4 0.074
spinal cord radial glial cell differentiation GO:0021531 2 0.073
regulation of hormone metabolic process GO:0032350 6 0.073
regulation of jun kinase activity GO:0043506 3 0.072
myeloid cell homeostasis GO:0002262 56 0.072
cell proliferation in forebrain GO:0021846 3 0.072
spinal cord anterior posterior patterning GO:0021512 1 0.070
nuclear division GO:0000280 23 0.070
somatic muscle development GO:0007525 4 0.070
regulation of endodermal cell differentiation GO:1903224 15 0.069
bmp signaling pathway involved in heart jogging GO:0003303 14 0.069
determination of left right asymmetry in lateral mesoderm GO:0003140 20 0.069
facial nucleus development GO:0021754 7 0.068
neuroblast differentiation GO:0014016 1 0.068
synapse assembly GO:0007416 9 0.068
segmentation GO:0035282 97 0.067
cell proliferation GO:0008283 80 0.067
macromolecular complex assembly GO:0065003 35 0.066
positive regulation of nucleobase containing compound metabolic process GO:0045935 69 0.066
negative regulation of wnt signaling pathway GO:0030178 30 0.066
homeostatic process GO:0042592 142 0.066
single organismal cell cell adhesion GO:0016337 29 0.065
regulation of organ growth GO:0046620 3 0.065
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.065
primary neural tube formation GO:0014020 1 0.065
regulation of synapse structure and activity GO:0050803 5 0.065
actin filament based process GO:0030029 64 0.065
brain segmentation GO:0035284 6 0.064
regulation of cell shape GO:0008360 1 0.064
heart jogging GO:0003146 40 0.064
cell cell signaling GO:0007267 52 0.063
embryonic skeletal system development GO:0048706 97 0.062
cell cycle g1 s phase transition GO:0044843 1 0.062
mitotic cell cycle process GO:1903047 48 0.062
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.062
regulation of cell cycle GO:0051726 52 0.061
stem cell division GO:0017145 1 0.060
skeletal system morphogenesis GO:0048705 102 0.060
negative regulation of axonogenesis GO:0050771 7 0.058
Zebrafish
neuromast development GO:0048884 46 0.057
regulation of epithelial to mesenchymal transition GO:0010717 3 0.056
establishment of organelle localization GO:0051656 45 0.056
regulation of nucleotide catabolic process GO:0030811 2 0.056
mitotic nuclear division GO:0007067 18 0.056
positive regulation of muscle tissue development GO:1901863 1 0.056
regulation of cardiac muscle tissue development GO:0055024 1 0.055
post anal tail morphogenesis GO:0036342 19 0.055
regulation of cellular protein metabolic process GO:0032268 52 0.055
heparan sulfate proteoglycan biosynthetic process GO:0015012 5 0.054
peptidyl serine phosphorylation GO:0018105 1 0.054
oxoacid metabolic process GO:0043436 31 0.054
regulation of filopodium assembly GO:0051489 2 0.053
epithelial cell proliferation GO:0050673 17 0.053
meiotic cell cycle process GO:1903046 3 0.053
protein complex assembly GO:0006461 30 0.053
fibroblast growth factor receptor signaling pathway GO:0008543 22 0.052
angioblast cell migration GO:0035476 9 0.052
Zebrafish
regulation of cell fate specification GO:0042659 20 0.051
positive regulation of biosynthetic process GO:0009891 68 0.051
negative regulation of epithelial cell proliferation GO:0050680 1 0.051
myotube differentiation GO:0014902 45 0.049
regulation of mesenchymal cell proliferation GO:0010464 1 0.049
endocrine system development GO:0035270 65 0.049
regulation of oocyte development GO:0060281 3 0.049
appendage development GO:0048736 80 0.048
negative regulation of bmp signaling pathway GO:0030514 13 0.048
regulation of wnt signaling pathway involved in digestive tract morphogenesis GO:2000056 2 0.048
response to fibroblast growth factor GO:0071774 22 0.048
positive regulation of transcription dna templated GO:0045893 57 0.047
cilium assembly GO:0042384 58 0.047
negative regulation of cellular metabolic process GO:0031324 77 0.047
positive regulation of fibroblast growth factor receptor signaling pathway GO:0045743 9 0.047
multi organism reproductive process GO:0044703 36 0.047
Worm
adherens junction organization GO:0034332 4 0.047
negative regulation of macromolecule biosynthetic process GO:0010558 48 0.047
regulation of axon regeneration GO:0048679 7 0.047
Zebrafish
fin regeneration GO:0031101 51 0.047
nucleus localization GO:0051647 8 0.047
establishment of localization in cell GO:0051649 77 0.047
regulation of purine nucleotide catabolic process GO:0033121 2 0.046
negative regulation of axon regeneration GO:0048681 4 0.046
Zebrafish
regulation of response to stress GO:0080134 36 0.046
Zebrafish
cellular protein complex assembly GO:0043623 19 0.045
peptidyl threonine modification GO:0018210 1 0.045
sensory epithelium regeneration GO:0070654 14 0.045
regulation of biological quality GO:0065008 263 0.045
Zebrafish
sulfur compound biosynthetic process GO:0044272 9 0.045
positive regulation of cell differentiation GO:0045597 30 0.045
sensory neuron axon guidance GO:0097374 3 0.044
developmental growth involved in morphogenesis GO:0060560 86 0.044
Zebrafish
positive regulation of nervous system development GO:0051962 25 0.044
cellular response to fibroblast growth factor stimulus GO:0044344 22 0.044
cellular response to organic substance GO:0071310 105 0.044
positive regulation of embryonic development GO:0040019 3 0.044
establishment or maintenance of apical basal cell polarity GO:0035088 12 0.043
negative regulation of biosynthetic process GO:0009890 55 0.043
multicellular organism reproduction GO:0032504 35 0.043
Worm
negative regulation of dna metabolic process GO:0051053 4 0.043
regulation of wound healing GO:0061041 2 0.042
anterior posterior axis specification GO:0009948 20 0.042
regulation of multicellular organism growth GO:0040014 4 0.042
positive regulation of multicellular organismal process GO:0051240 52 0.041
regulation of nucleoside metabolic process GO:0009118 2 0.041
negative regulation of nucleobase containing compound metabolic process GO:0045934 59 0.041
establishment of spindle localization GO:0051293 12 0.041
otic vesicle development GO:0071599 42 0.041
renal system development GO:0072001 94 0.040
establishment or maintenance of bipolar cell polarity GO:0061245 12 0.040
glycoprotein metabolic process GO:0009100 23 0.040
odontogenesis of dentin containing tooth GO:0042475 1 0.040
developmental cell growth GO:0048588 52 0.040
Zebrafish
embryonic cranial skeleton morphogenesis GO:0048701 90 0.040
establishment of protein localization to organelle GO:0072594 4 0.039
embryonic organ morphogenesis GO:0048562 274 0.039
regulation of vitamin metabolic process GO:0030656 6 0.039
single fertilization GO:0007338 3 0.039
diterpenoid biosynthetic process GO:0016102 7 0.039
modification dependent protein catabolic process GO:0019941 3 0.038
regulation of cell development GO:0060284 100 0.038
Zebrafish
endothelial cell differentiation GO:0045446 20 0.038
wnt signaling pathway involved in dorsal ventral axis specification GO:0044332 5 0.038
lamellipodium assembly GO:0030032 1 0.038
auditory receptor cell fate commitment GO:0009912 4 0.038
regulation of retinoic acid biosynthetic process GO:1900052 6 0.038
cellular response to chemical stimulus GO:0070887 157 0.038
g1 s transition of mitotic cell cycle GO:0000082 1 0.037
regulation of extent of cell growth GO:0061387 29 0.037
Zebrafish
homeostasis of number of cells GO:0048872 62 0.037
positive regulation of cellular catabolic process GO:0031331 3 0.037
establishment of mitotic spindle orientation GO:0000132 10 0.037
hepatic duct development GO:0061011 2 0.037
positive regulation of catabolic process GO:0009896 4 0.037
cellular localization GO:0051641 97 0.036
positive regulation of cellular biosynthetic process GO:0031328 68 0.036
glycoprotein biosynthetic process GO:0009101 21 0.036
positive regulation of mesenchymal cell proliferation GO:0002053 1 0.036
regulation of isoprenoid metabolic process GO:0019747 6 0.036
regulation of mesoderm development GO:2000380 11 0.036
bmp signaling pathway involved in determination of left right symmetry GO:0003154 14 0.036
primitive hemopoiesis GO:0060215 27 0.036
reproduction GO:0000003 40 0.035
Worm
pharyngeal system development GO:0060037 18 0.035
cellular hormone metabolic process GO:0034754 19 0.035

ephb4b disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.190
musculoskeletal system disease DOID:17 0 0.094
connective tissue disease DOID:65 0 0.077
nervous system disease DOID:863 0 0.040