Danio rerio

0 known processes

ercc2

excision repair cross-complementing rodent repair deficiency, complementation group 2

(Aliases: zgc:56365,MGC56365)

ercc2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
nucleobase containing compound metabolic process GO:0006139 274 0.461
nitrogen compound metabolic process GO:0006807 319 0.412
cellular macromolecule biosynthetic process GO:0034645 224 0.406
cellular nitrogen compound metabolic process GO:0034641 290 0.385
nucleic acid metabolic process GO:0090304 244 0.354
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.347
larval development GO:0002164 2 0.274
regulation of gene expression GO:0010468 265 0.257
heterocycle metabolic process GO:0046483 290 0.249
regulation of macromolecule metabolic process GO:0060255 317 0.246
regulation of rna metabolic process GO:0051252 224 0.242
regulation of epithelial cell proliferation GO:0050678 3 0.233
female gonad development GO:0008585 4 0.204
regulation of nucleic acid templated transcription GO:1903506 213 0.199
cellular aromatic compound metabolic process GO:0006725 295 0.188
protein metabolic process GO:0019538 183 0.178
regulation of biosynthetic process GO:0009889 250 0.172
sister chromatid cohesion GO:0007062 2 0.168
single organism organelle organization GO:1902589 199 0.145
multi organism process GO:0051704 134 0.144
regulation of metabolic process GO:0019222 359 0.139
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.138
cellular macromolecule metabolic process GO:0044260 391 0.134
regulation of primary metabolic process GO:0080090 311 0.133
ribonucleoside monophosphate catabolic process GO:0009158 4 0.131
biosynthetic process GO:0009058 294 0.131
macromolecule modification GO:0043412 111 0.131
meiotic nuclear division GO:0007126 4 0.125
regulation of nitrogen compound metabolic process GO:0051171 251 0.123
rna biosynthetic process GO:0032774 181 0.123
cellular nitrogen compound biosynthetic process GO:0044271 218 0.112
organelle fission GO:0048285 23 0.110
gene expression GO:0010467 252 0.109
organic cyclic compound metabolic process GO:1901360 301 0.109
macromolecule biosynthetic process GO:0009059 227 0.106
female sex differentiation GO:0046660 4 0.104
organelle organization GO:0006996 227 0.103
single organism metabolic process GO:0044710 217 0.099
negative regulation of mitosis GO:0045839 3 0.098
regulation of meiotic cell cycle GO:0051445 1 0.096
regulation of establishment of protein localization GO:0070201 4 0.095
regulation of protein catabolic process GO:0042176 1 0.094
positive regulation of biological process GO:0048518 253 0.091
regulation of cellular biosynthetic process GO:0031326 245 0.091
chromosome organization GO:0051276 31 0.086
positive regulation of cellular component biogenesis GO:0044089 3 0.086
heterocycle biosynthetic process GO:0018130 215 0.085
meiotic cell cycle process GO:1903046 3 0.083
peptidyl serine phosphorylation GO:0018105 1 0.083
regulation of cellular protein catabolic process GO:1903362 1 0.082
male meiosis GO:0007140 2 0.082
immunoglobulin mediated immune response GO:0016064 3 0.082
cellular protein metabolic process GO:0044267 129 0.079
stem cell proliferation GO:0072089 4 0.079
mrna metabolic process GO:0016071 20 0.079
regulation of protein import into nucleus GO:0042306 2 0.078
purine nucleoside monophosphate catabolic process GO:0009128 4 0.076
phosphorus metabolic process GO:0006793 109 0.076
organic cyclic compound biosynthetic process GO:1901362 223 0.076
nucleic acid templated transcription GO:0097659 181 0.074
positive regulation of cellular metabolic process GO:0031325 94 0.073
organic substance biosynthetic process GO:1901576 289 0.073
regulation of transcription dna templated GO:0006355 213 0.070
peptidyl serine modification GO:0018209 2 0.070
macromolecular complex subunit organization GO:0043933 74 0.070
regulation of cellular metabolic process GO:0031323 320 0.069
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 1 0.069
transcription dna templated GO:0006351 181 0.067
immune system development GO:0002520 191 0.067
rna metabolic process GO:0016070 219 0.067
nucleoside monophosphate catabolic process GO:0009125 4 0.065
regulation of rna biosynthetic process GO:2001141 213 0.065
negative regulation of biological process GO:0048519 304 0.065
protein import GO:0017038 3 0.064
meiosis ii GO:0007135 1 0.064
response to oxygen radical GO:0000305 2 0.063
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.063
symbiosis encompassing mutualism through parasitism GO:0044403 4 0.063
positive regulation of map kinase activity GO:0043406 3 0.062
immune system process GO:0002376 241 0.062
regulation of macromolecule biosynthetic process GO:0010556 225 0.060
programmed cell death GO:0012501 119 0.059
hematopoietic or lymphoid organ development GO:0048534 191 0.059
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.058
chromatin modification GO:0016568 21 0.057
negative regulation of cellular metabolic process GO:0031324 77 0.055
regulation of protein complex assembly GO:0043254 3 0.055
atp catabolic process GO:0006200 4 0.053
nuclear transport GO:0051169 4 0.053
spliceosomal complex assembly GO:0000245 1 0.053
cellular component assembly GO:0022607 170 0.052
reproductive process GO:0022414 40 0.050
cellular protein modification process GO:0006464 100 0.050
protein localization to nucleus GO:0034504 3 0.050
positive regulation of catabolic process GO:0009896 4 0.050
zymogen activation GO:0031638 3 0.049
single organism nuclear import GO:1902593 3 0.049
response to cadmium ion GO:0046686 14 0.048
protein modification process GO:0036211 100 0.047
development of primary female sexual characteristics GO:0046545 4 0.046
cytokinetic process GO:0032506 2 0.045
cellular biosynthetic process GO:0044249 286 0.045
regulation of protein localization to nucleus GO:1900180 2 0.045
positive regulation of cellular process GO:0048522 201 0.045
positive regulation of cellular amine metabolic process GO:0033240 0 0.044
regulation of cytoplasmic transport GO:1903649 4 0.044
multi organism cellular process GO:0044764 2 0.044
negative regulation of macromolecule metabolic process GO:0010605 76 0.044
positive regulation of epithelial cell proliferation GO:0050679 1 0.044
cellular component biogenesis GO:0044085 178 0.044
negative regulation of dna recombination GO:0045910 2 0.043
regulation of biological quality GO:0065008 263 0.043
regulation of cellular amino acid metabolic process GO:0006521 0 0.042
positive regulation of stress activated protein kinase signaling cascade GO:0070304 3 0.040
pancreas development GO:0031016 84 0.040
negative regulation of nuclear division GO:0051784 3 0.040
cellular protein catabolic process GO:0044257 4 0.039
positive regulation of chromosome organization GO:2001252 1 0.039
liver morphogenesis GO:0072576 8 0.038
positive regulation of muscle tissue development GO:1901863 1 0.038
maintenance of location GO:0051235 4 0.038
cellular response to starvation GO:0009267 1 0.038
cell part morphogenesis GO:0032990 246 0.037
protein acetylation GO:0006473 2 0.037
nuclear import GO:0051170 3 0.037
wnt signaling pathway GO:0016055 80 0.037
cellular macromolecular complex assembly GO:0034622 24 0.037
response to monosaccharide GO:0034284 3 0.036
viral process GO:0016032 1 0.036
activation of mapk activity GO:0000187 3 0.035
peptidyl lysine acetylation GO:0018394 2 0.034
positive regulation of jun kinase activity GO:0043507 2 0.034
activation of jun kinase activity GO:0007257 2 0.034
regulation of dna replication GO:0006275 3 0.034
nucleocytoplasmic transport GO:0006913 4 0.033
multicellular organism reproduction GO:0032504 35 0.033
oocyte anterior posterior axis specification GO:0007314 4 0.033
hemopoiesis GO:0030097 183 0.032
protein acylation GO:0043543 3 0.032
determination of bilateral symmetry GO:0009855 204 0.032
covalent chromatin modification GO:0016569 20 0.032
aging GO:0007568 2 0.031
production of molecular mediator of immune response GO:0002440 2 0.031
rna localization GO:0006403 4 0.031
nucleobase containing compound biosynthetic process GO:0034654 205 0.031
b cell activation GO:0042113 2 0.031
positive regulation of canonical wnt signaling pathway GO:0090263 4 0.031
interspecies interaction between organisms GO:0044419 4 0.031
regulation of protein ubiquitination GO:0031396 3 0.030
positive regulation of chromatin modification GO:1903310 1 0.030
cell cycle GO:0007049 93 0.030
protein targeting to nucleus GO:0044744 3 0.030
response to drug GO:0042493 3 0.030
positive regulation of molecular function GO:0044093 33 0.029
protein complex biogenesis GO:0070271 30 0.029
positive regulation of dna metabolic process GO:0051054 1 0.028
modification dependent protein catabolic process GO:0019941 3 0.028
nephron epithelium morphogenesis GO:0072088 1 0.028
cellular response to organic substance GO:0071310 105 0.027
aromatic compound biosynthetic process GO:0019438 217 0.027
meiotic chromosome segregation GO:0045132 3 0.027
carboxylic acid metabolic process GO:0019752 22 0.027
small molecule metabolic process GO:0044281 77 0.026
regulation of cellular ketone metabolic process GO:0010565 7 0.026
cytoplasm organization GO:0007028 4 0.026
chordate embryonic development GO:0043009 271 0.026
regulation of cellular amine metabolic process GO:0033238 0 0.026
positive regulation of histone modification GO:0031058 1 0.026
mitotic nuclear division GO:0007067 18 0.026
chromosome organization involved in meiosis GO:0070192 1 0.026
protein phosphorylation GO:0006468 47 0.026
meiotic spindle organization GO:0000212 1 0.026
developmental process involved in reproduction GO:0003006 27 0.025
regulation of cytokine production GO:0001817 3 0.025
generation of neurons GO:0048699 385 0.025
regulation of cell maturation GO:1903429 1 0.025
amine metabolic process GO:0009308 2 0.025
internal peptidyl lysine acetylation GO:0018393 2 0.025
autophagy GO:0006914 4 0.025
methylation GO:0032259 22 0.025
adherens junction organization GO:0034332 4 0.025
regulation of response to stimulus GO:0048583 269 0.024
peptidyl threonine phosphorylation GO:0018107 1 0.024
regulation of molecular function GO:0065009 70 0.024
cell substrate adhesion GO:0031589 4 0.024
response to glucocorticoid GO:0051384 1 0.024
cell substrate junction assembly GO:0007044 2 0.024
regulation of stem cell proliferation GO:0072091 2 0.024
histone modification GO:0016570 20 0.023
cell cycle process GO:0022402 53 0.023
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.023
liver development GO:0001889 96 0.023
positive regulation of cell cycle GO:0045787 3 0.023
cytokinesis GO:0000910 3 0.023
gamete generation GO:0007276 33 0.023
response to corticosteroid GO:0031960 1 0.023
determination of dorsal identity GO:0048263 13 0.023
protein complex disassembly GO:0043241 1 0.023
positive regulation of stress activated mapk cascade GO:0032874 3 0.023
microtubule polymerization or depolymerization GO:0031109 3 0.022
carbohydrate homeostasis GO:0033500 1 0.022
stem cell maintenance GO:0019827 4 0.022
mitotic sister chromatid segregation GO:0000070 6 0.022
digestive system development GO:0055123 289 0.022
chromatin organization GO:0006325 22 0.022
neuroblast proliferation GO:0007405 2 0.022
regulation of nucleocytoplasmic transport GO:0046822 2 0.022
regulation of protein transport GO:0051223 3 0.022
positive regulation of nucleobase containing compound metabolic process GO:0045935 69 0.022
positive regulation of multi organism process GO:0043902 3 0.021
intrinsic apoptotic signaling pathway in response to oxidative stress GO:0008631 2 0.021
negative regulation of cytoplasmic transport GO:1903650 2 0.021
response to organic substance GO:0010033 153 0.021
positive regulation of muscle organ development GO:0048636 1 0.021
regulation of signaling GO:0023051 235 0.021
regulation of multicellular organismal process GO:0051239 277 0.021
regulation of cell matrix adhesion GO:0001952 1 0.021
mrna 3 end processing GO:0031124 2 0.021
pole plasm assembly GO:0007315 4 0.021
regulation of cellular protein metabolic process GO:0032268 52 0.021
negative regulation of histone modification GO:0031057 1 0.021
convergent extension involved in gastrulation GO:0060027 71 0.021
cell aging GO:0007569 2 0.020
myeloid cell differentiation GO:0030099 86 0.020
cellular response to nutrient levels GO:0031669 2 0.020
stem cell division GO:0017145 1 0.020
phosphate containing compound metabolic process GO:0006796 108 0.020
regulation of apoptotic process GO:0042981 98 0.020
death GO:0016265 121 0.020
positive regulation of biosynthetic process GO:0009891 68 0.020
dna metabolic process GO:0006259 27 0.020
positive regulation of macromolecule metabolic process GO:0010604 93 0.020
histone h3 k4 methylation GO:0051568 2 0.020
central nervous system development GO:0007417 387 0.020
proteasomal protein catabolic process GO:0010498 2 0.019
regulation of protein targeting GO:1903533 2 0.019
signal transduction GO:0007165 455 0.019
response to hexose GO:0009746 3 0.019
cellular process involved in reproduction in multicellular organism GO:0022412 28 0.019
cellular amine metabolic process GO:0044106 2 0.019
positive regulation of transport GO:0051050 2 0.019
negative regulation of dna metabolic process GO:0051053 4 0.019
skeletal system development GO:0001501 181 0.019
chromosome localization GO:0050000 2 0.019
multicellular organismal reproductive process GO:0048609 35 0.019
adult behavior GO:0030534 2 0.018
negative regulation of cell division GO:0051782 4 0.018
cell death GO:0008219 121 0.018
response to copper ion GO:0046688 13 0.018
pathway restricted smad protein phosphorylation GO:0060389 1 0.018
regulation of reproductive process GO:2000241 4 0.018
purine ribonucleoside monophosphate catabolic process GO:0009169 4 0.018
cell projection organization GO:0030030 284 0.018
organonitrogen compound metabolic process GO:1901564 74 0.018
response to stress GO:0006950 263 0.018
response to chemical GO:0042221 320 0.018
cellular component morphogenesis GO:0032989 336 0.018
negative regulation of epithelial cell proliferation GO:0050680 1 0.018
sister chromatid segregation GO:0000819 6 0.017
single organism transport GO:0044765 206 0.017
protein complex assembly GO:0006461 30 0.017
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.017
internal protein amino acid acetylation GO:0006475 2 0.017
regulation of protein binding GO:0043393 3 0.017
cellular amino acid metabolic process GO:0006520 7 0.017
cellular ketone metabolic process GO:0042180 11 0.017
recombinational repair GO:0000725 1 0.017
b cell mediated immunity GO:0019724 3 0.017
regulation of chromosome segregation GO:0051983 1 0.017
b cell differentiation GO:0030183 1 0.017
regulation of signal transduction GO:0009966 225 0.017
regulation of cardiac muscle tissue development GO:0055024 1 0.017
innate immune response GO:0045087 13 0.017
regulation of cell activation GO:0050865 1 0.017
positive regulation of cellular protein metabolic process GO:0032270 22 0.017
negative regulation of cellular biosynthetic process GO:0031327 55 0.017
positive regulation of cellular catabolic process GO:0031331 3 0.017
regulation of wnt signaling pathway GO:0030111 53 0.017
protein import into nucleus GO:0006606 3 0.017
connective tissue development GO:0061448 99 0.017
single organism localization GO:1902578 225 0.016
nephron tubule morphogenesis GO:0072078 1 0.016
nik nf kappab signaling GO:0038061 1 0.016
notochord development GO:0030903 54 0.016
cell proliferation in forebrain GO:0021846 3 0.016
macromolecular complex assembly GO:0065003 35 0.016
immunoglobulin production GO:0002377 1 0.016
positive regulation of signaling GO:0023056 56 0.016
mitotic cell cycle GO:0000278 64 0.016
establishment of localization GO:0051234 244 0.016
proepicardium development GO:0003342 4 0.016
neuron projection morphogenesis GO:0048812 161 0.016
regulation of dna recombination GO:0000018 2 0.016
negative regulation of mitotic cell cycle GO:0045930 11 0.016
regulation of binding GO:0051098 3 0.016
regulation of endothelial cell proliferation GO:0001936 1 0.016
positive regulation of macromolecule biosynthetic process GO:0010557 59 0.016
positive regulation of peptidyl tyrosine phosphorylation GO:0050731 1 0.016
cell migration involved in gastrulation GO:0042074 79 0.015
somatic stem cell maintenance GO:0035019 1 0.015
immune response GO:0006955 28 0.015
mitotic dna damage checkpoint GO:0044773 4 0.015
dna biosynthetic process GO:0071897 3 0.015
positive regulation of cell division GO:0051781 2 0.015
response to transition metal nanoparticle GO:1990267 28 0.015
positive regulation of metabolic process GO:0009893 108 0.015
phosphorylation GO:0016310 69 0.015
neuron projection development GO:0031175 180 0.015
optic placode formation GO:0001743 4 0.015
cytoskeleton dependent cytokinesis GO:0061640 3 0.015
spinal cord anterior posterior patterning GO:0021512 1 0.014
cell morphogenesis involved in differentiation GO:0000904 195 0.014
peptidyl threonine modification GO:0018210 1 0.014
cellular component disassembly GO:0022411 1 0.014
female meiotic division GO:0007143 2 0.014
organelle localization GO:0051640 49 0.014
response to abiotic stimulus GO:0009628 122 0.014
negative regulation of intracellular transport GO:0032387 3 0.014
head development GO:0060322 303 0.014
negative regulation of dna replication GO:0008156 2 0.014
negative regulation of cellular catabolic process GO:0031330 3 0.014
establishment of endothelial blood brain barrier GO:0014045 2 0.014
response to external biotic stimulus GO:0043207 97 0.014
hepatocyte proliferation GO:0072574 2 0.014
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 68 0.014
regulation of cell communication GO:0010646 232 0.014
negative regulation of macromolecule biosynthetic process GO:0010558 48 0.014
epithelial cell proliferation involved in liver morphogenesis GO:0072575 2 0.014
positive regulation of erk1 and erk2 cascade GO:0070374 2 0.014
mitotic dna integrity checkpoint GO:0044774 4 0.014
homologous chromosome segregation GO:0045143 1 0.014
macromolecular complex disassembly GO:0032984 1 0.013
cellular response to growth factor stimulus GO:0071363 39 0.013
superoxide metabolic process GO:0006801 2 0.013
meiosis i GO:0007127 1 0.013
renal tubule morphogenesis GO:0061333 1 0.013
cellular response to stress GO:0033554 62 0.013
catabolic process GO:0009056 32 0.013
regulation of jun kinase activity GO:0043506 3 0.013
positive regulation of cytoskeleton organization GO:0051495 3 0.013
negative regulation of hormone secretion GO:0046888 2 0.013
adherens junction assembly GO:0034333 1 0.013
protein homooligomerization GO:0051260 3 0.013
specification of symmetry GO:0009799 204 0.013
pigment granule organization GO:0048753 4 0.013
translational initiation GO:0006413 3 0.013
cell death in response to oxidative stress GO:0036473 2 0.013
negative regulation of chromosome organization GO:2001251 1 0.013
regulation of protein modification by small protein conjugation or removal GO:1903320 3 0.013
positive regulation of epithelial cell differentiation GO:0030858 2 0.013
cellular response to external stimulus GO:0071496 2 0.013
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.013
dicarboxylic acid metabolic process GO:0043648 1 0.012
positive regulation of protein complex assembly GO:0031334 2 0.012
regulation of cellular component organization GO:0051128 86 0.012
cellular response to extracellular stimulus GO:0031668 2 0.012
extrinsic apoptotic signaling pathway via death domain receptors GO:0008625 1 0.012
regulation of dna metabolic process GO:0051052 11 0.012
canonical wnt signaling pathway GO:0060070 48 0.012
protein modification by small protein conjugation or removal GO:0070647 14 0.012
ion transport GO:0006811 114 0.012
mitotic metaphase plate congression GO:0007080 1 0.012
negative regulation of catabolic process GO:0009895 3 0.012
cell matrix adhesion GO:0007160 4 0.012
positive regulation of response to stimulus GO:0048584 80 0.012
cell division GO:0051301 20 0.012
protein destabilization GO:0031648 1 0.012
regulation of organ growth GO:0046620 3 0.012
positive regulation of protein metabolic process GO:0051247 23 0.012
cellular response to hypoxia GO:0071456 1 0.012
negative regulation of cell cycle GO:0045786 14 0.012
regulation of stem cell differentiation GO:2000736 4 0.012
exocrine pancreas development GO:0031017 28 0.011
ovulation cycle GO:0042698 2 0.011
regulation of protein metabolic process GO:0051246 56 0.011
response to ketone GO:1901654 1 0.011
bone remodeling GO:0046849 2 0.011
regulation of symbiosis encompassing mutualism through parasitism GO:0043903 1 0.011
regulation of nucleoside metabolic process GO:0009118 2 0.011
positive regulation of immune response GO:0050778 11 0.011
spermatid development GO:0007286 2 0.011
positive regulation of skeletal muscle tissue development GO:0048643 1 0.011
neuron development GO:0048666 262 0.011
negative regulation of translation GO:0017148 1 0.011
negative regulation of axon regeneration GO:0048681 4 0.011
protein localization GO:0008104 40 0.011
lateral line development GO:0048882 66 0.011
negative regulation of myeloid cell differentiation GO:0045638 1 0.011
extrinsic apoptotic signaling pathway GO:0097191 3 0.011
positive regulation of production of molecular mediator of immune response GO:0002702 1 0.011
positive regulation of apoptotic signaling pathway GO:2001235 1 0.011
dna methylation on cytosine GO:0032776 3 0.011
cellular response to endogenous stimulus GO:0071495 68 0.011
hematopoietic stem cell differentiation GO:0060218 20 0.011
maternal determination of anterior posterior axis embryo GO:0008358 4 0.011
thrombocyte differentiation GO:0002574 4 0.011
cytoskeleton organization GO:0007010 96 0.011
microtubule depolymerization GO:0007019 1 0.010
digestive tract morphogenesis GO:0048546 231 0.010
cellular response to biotic stimulus GO:0071216 3 0.010
hormone secretion GO:0046879 2 0.010
reciprocal meiotic recombination GO:0007131 1 0.010
ovulation cycle process GO:0022602 2 0.010
dna templated transcription initiation GO:0006352 1 0.010
leukocyte homeostasis GO:0001776 2 0.010
regulation of production of molecular mediator of immune response GO:0002700 1 0.010
positive regulation of neuron death GO:1901216 1 0.010
regulation of response to cytokine stimulus GO:0060759 3 0.010
negative regulation of gene expression GO:0010629 65 0.010
cellular catabolic process GO:0044248 27 0.010

ercc2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.013