Danio rerio

0 known processes

esd

esterase D/formylglutathione hydrolase

(Aliases: zgc:111984,wu:fb58f05)

esd biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
hydrogen peroxide metabolic process GO:0042743 2 0.626
cellular hormone metabolic process GO:0034754 19 0.190
regulation of nucleic acid templated transcription GO:1903506 213 0.179
determination of left right symmetry GO:0007368 179 0.162
small molecule catabolic process GO:0044282 3 0.133
cellular response to lipopolysaccharide GO:0071222 3 0.128
cellular modified amino acid metabolic process GO:0006575 3 0.120
nucleic acid metabolic process GO:0090304 244 0.115
regulation of cytokine production GO:0001817 3 0.108
macromolecule biosynthetic process GO:0009059 227 0.107
rna biosynthetic process GO:0032774 181 0.106
adult behavior GO:0030534 2 0.105
cellular response to molecule of bacterial origin GO:0071219 3 0.097
cellular response to oxygen radical GO:0071450 2 0.090
response to hydrogen peroxide GO:0042542 3 0.089
rna metabolic process GO:0016070 219 0.087
nucleic acid templated transcription GO:0097659 181 0.083
signal transduction GO:0007165 455 0.081
gene expression GO:0010467 252 0.078
reactive oxygen species metabolic process GO:0072593 6 0.078
regulation of nitrogen compound metabolic process GO:0051171 251 0.078
transcription dna templated GO:0006351 181 0.077
cellular response to biotic stimulus GO:0071216 3 0.071
regulation of macromolecule biosynthetic process GO:0010556 225 0.068
transcription from rna polymerase ii promoter GO:0006366 80 0.067
organic acid metabolic process GO:0006082 31 0.065
oxoacid metabolic process GO:0043436 31 0.063
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.062
positive regulation of transport GO:0051050 2 0.062
regulation of developmental process GO:0050793 247 0.060
specification of symmetry GO:0009799 204 0.059
cellular biosynthetic process GO:0044249 286 0.057
regulation of rna biosynthetic process GO:2001141 213 0.056
determination of bilateral symmetry GO:0009855 204 0.056
regulation of metabolic process GO:0019222 359 0.056
regulation of multicellular organism growth GO:0040014 4 0.056
response to chemical GO:0042221 320 0.054
regulation of transcription dna templated GO:0006355 213 0.054
small molecule metabolic process GO:0044281 77 0.054
cell proliferation GO:0008283 80 0.054
alcohol biosynthetic process GO:0046165 2 0.053
regulation of primary metabolic process GO:0080090 311 0.053
cellular macromolecule biosynthetic process GO:0034645 224 0.053
regulation of biological quality GO:0065008 263 0.053
nucleobase containing compound biosynthetic process GO:0034654 205 0.053
nitrogen compound metabolic process GO:0006807 319 0.053
response to oxygen containing compound GO:1901700 55 0.052
cellular macromolecule metabolic process GO:0044260 391 0.052
long chain fatty acid transport GO:0015909 1 0.051
regulation of cellular biosynthetic process GO:0031326 245 0.051
organic cyclic compound biosynthetic process GO:1901362 223 0.049
cellular response to reactive oxygen species GO:0034614 2 0.049
cellular aldehyde metabolic process GO:0006081 4 0.048
regulation of signal transduction GO:0009966 225 0.048
response to lipid GO:0033993 60 0.048
superoxide metabolic process GO:0006801 2 0.048
multicellular organism growth GO:0035264 4 0.047
hemopoiesis GO:0030097 183 0.046
larval development GO:0002164 2 0.046
cellular component morphogenesis GO:0032989 336 0.044
regulation of blood pressure GO:0008217 1 0.043
regulation of transcription from rna polymerase ii promoter GO:0006357 114 0.042
response to oxygen radical GO:0000305 2 0.042
aromatic compound biosynthetic process GO:0019438 217 0.041
cellular nitrogen compound biosynthetic process GO:0044271 218 0.041
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.040
regulation of gene expression GO:0010468 265 0.039
cell surface receptor signaling pathway GO:0007166 325 0.039
regulation of biosynthetic process GO:0009889 250 0.039
gland development GO:0048732 143 0.039
negative regulation of extrinsic apoptotic signaling pathway GO:2001237 2 0.038
cellular response to superoxide GO:0071451 2 0.038
cell morphogenesis GO:0000902 289 0.038
oxidation reduction process GO:0055114 41 0.038
phagocytosis GO:0006909 3 0.037
organonitrogen compound metabolic process GO:1901564 74 0.036
regulation of cell differentiation GO:0045595 142 0.036
carboxylic acid metabolic process GO:0019752 22 0.036
positive regulation of map kinase activity GO:0043406 3 0.035
aging GO:0007568 2 0.035
protein stabilization GO:0050821 2 0.035
response to superoxide GO:0000303 2 0.035
regulation of reproductive process GO:2000241 4 0.035
regulation of cellular metabolic process GO:0031323 320 0.035
maintenance of location GO:0051235 4 0.035
regulation of reactive oxygen species metabolic process GO:2000377 2 0.034
negative regulation of leukocyte differentiation GO:1902106 1 0.034
regulation of multicellular organismal process GO:0051239 277 0.034
energy reserve metabolic process GO:0006112 2 0.033
negative regulation of signal transduction in absence of ligand GO:1901099 1 0.033
gtp metabolic process GO:0046039 4 0.033
negative regulation of catabolic process GO:0009895 3 0.033
regulation of macromolecule metabolic process GO:0060255 317 0.033
regulation of cellular ketone metabolic process GO:0010565 7 0.032
cellular nitrogen compound metabolic process GO:0034641 290 0.031
organic cyclic compound metabolic process GO:1901360 301 0.031
camera type eye development GO:0043010 222 0.030
regulation of rna metabolic process GO:0051252 224 0.030
single organism metabolic process GO:0044710 217 0.030
fatty acid oxidation GO:0019395 1 0.029
negative regulation of intracellular transport GO:0032387 3 0.029
regulation of extrinsic apoptotic signaling pathway GO:2001236 3 0.029
response to organic substance GO:0010033 153 0.028
heterocycle biosynthetic process GO:0018130 215 0.028
mononuclear cell proliferation GO:0032943 1 0.028
cellular aromatic compound metabolic process GO:0006725 295 0.027
leukocyte proliferation GO:0070661 1 0.027
carboxylic acid catabolic process GO:0046395 3 0.027
retinoic acid receptor signaling pathway GO:0048384 16 0.027
response to external biotic stimulus GO:0043207 97 0.027
positive regulation of muscle cell differentiation GO:0051149 1 0.026
nuclear transport GO:0051169 4 0.026
amine metabolic process GO:0009308 2 0.026
negative regulation of reproductive process GO:2000242 3 0.026
protein localization to nucleus GO:0034504 3 0.026
negative regulation of signaling GO:0023057 96 0.025
extrinsic apoptotic signaling pathway GO:0097191 3 0.025
negative regulation of cellular process GO:0048523 283 0.025
cellular amino acid metabolic process GO:0006520 7 0.025
organic substance biosynthetic process GO:1901576 289 0.025
regulation of transmembrane transporter activity GO:0022898 2 0.025
hematopoietic or lymphoid organ development GO:0048534 191 0.024
monoamine transport GO:0015844 1 0.024
negative regulation of nucleocytoplasmic transport GO:0046823 2 0.024
phosphate containing compound metabolic process GO:0006796 108 0.024
programmed cell death GO:0012501 119 0.024
negative regulation of cell communication GO:0010648 96 0.024
hepaticobiliary system development GO:0061008 98 0.024
negative regulation of nitrogen compound metabolic process GO:0051172 59 0.024
response to inorganic substance GO:0010035 38 0.023
negative regulation of signal transduction GO:0009968 94 0.023
regulation of blood vessel size GO:0050880 2 0.023
cellular amide metabolic process GO:0043603 4 0.023
cell part morphogenesis GO:0032990 246 0.023
ribosome assembly GO:0042255 1 0.023
negative regulation of cytoplasmic transport GO:1903650 2 0.023
cellular response to chemical stimulus GO:0070887 157 0.023
sensory organ development GO:0007423 393 0.023
protein acetylation GO:0006473 2 0.022
hormone metabolic process GO:0042445 19 0.022
death GO:0016265 121 0.022
negative regulation of nucleobase containing compound metabolic process GO:0045934 59 0.022
regulation of response to biotic stimulus GO:0002831 2 0.022
liver development GO:0001889 96 0.022
cellular response to lipid GO:0071396 39 0.022
biosynthetic process GO:0009058 294 0.022
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 2 0.021
cell projection morphogenesis GO:0048858 244 0.021
lateral inhibition GO:0046331 1 0.021
regulation of nucleotide metabolic process GO:0006140 17 0.021
intracellular signal transduction GO:0035556 85 0.021
fatty acid transport GO:0015908 1 0.021
embryonic organ development GO:0048568 381 0.021
negative regulation of cellular macromolecule biosynthetic process GO:2000113 48 0.021
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.021
regulation of cellular amine metabolic process GO:0033238 0 0.021
guanosine containing compound catabolic process GO:1901069 2 0.021
homeostatic process GO:0042592 142 0.021
cellular protein metabolic process GO:0044267 129 0.021
eye development GO:0001654 277 0.021
cellular amine metabolic process GO:0044106 2 0.020
extracellular structure organization GO:0043062 27 0.020
regulation of nucleoside metabolic process GO:0009118 2 0.020
protein acylation GO:0043543 3 0.020
positive regulation of response to wounding GO:1903036 5 0.020
response to molecule of bacterial origin GO:0002237 14 0.020
regulation of binding GO:0051098 3 0.020
phosphorus metabolic process GO:0006793 109 0.020
lymphocyte proliferation GO:0046651 1 0.020
negative regulation of biological process GO:0048519 304 0.020
regulation of cellular amino acid metabolic process GO:0006521 0 0.019
heart looping GO:0001947 94 0.019
neurotransmitter transport GO:0006836 2 0.019
neuron neuron synaptic transmission GO:0007270 1 0.019
regulation of wound healing GO:0061041 2 0.019
regulation of response to stimulus GO:0048583 269 0.019
cell morphogenesis involved in differentiation GO:0000904 195 0.018
cellular response to organic substance GO:0071310 105 0.018
response to stress GO:0006950 263 0.018
negative regulation of rna metabolic process GO:0051253 48 0.018
response to ketone GO:1901654 1 0.018
embryonic heart tube development GO:0035050 133 0.018
positive regulation of cytokine production GO:0001819 2 0.018
regulation of apoptotic process GO:0042981 98 0.018
regulation of cell activation GO:0050865 1 0.018
diterpenoid metabolic process GO:0016101 15 0.017
negative regulation of metabolic process GO:0009892 86 0.017
response to reactive oxygen species GO:0000302 5 0.017
positive regulation of cellular amine metabolic process GO:0033240 0 0.017
organic hydroxy compound biosynthetic process GO:1901617 6 0.017
purine containing compound metabolic process GO:0072521 29 0.017
peptide metabolic process GO:0006518 1 0.017
response to hormone GO:0009725 48 0.017
positive regulation of secretion GO:0051047 1 0.016
negative regulation of cellular biosynthetic process GO:0031327 55 0.016
apoptotic process GO:0006915 116 0.016
negative regulation of cellular catabolic process GO:0031330 3 0.016
regulation of nucleocytoplasmic transport GO:0046822 2 0.016
sensory organ morphogenesis GO:0090596 200 0.016
positive regulation of biological process GO:0048518 253 0.016
cellular response to stress GO:0033554 62 0.016
regulation of transporter activity GO:0032409 2 0.016
negative regulation of macromolecule metabolic process GO:0010605 76 0.016
heterocycle metabolic process GO:0046483 290 0.016
morphogenesis of an epithelium GO:0002009 333 0.016
response to endogenous stimulus GO:0009719 83 0.016
peptidyl lysine acetylation GO:0018394 2 0.016
production of molecular mediator of immune response GO:0002440 2 0.016
regulation of metal ion transport GO:0010959 4 0.016
response to lipopolysaccharide GO:0032496 13 0.016
urogenital system development GO:0001655 97 0.015
regulation of signaling GO:0023051 235 0.015
generation of neurons GO:0048699 385 0.015
negative regulation of nucleic acid templated transcription GO:1903507 45 0.015
response to bacterium GO:0009617 58 0.015
cell aging GO:0007569 2 0.015
regulation of cellular response to oxidative stress GO:1900407 2 0.015
tube morphogenesis GO:0035239 349 0.015
respiratory burst GO:0045730 2 0.015
negative regulation of gene expression GO:0010629 65 0.015
regulation of protein import into nucleus GO:0042306 2 0.015
reactive oxygen species biosynthetic process GO:1903409 1 0.015
protein modification process GO:0036211 100 0.015
lipid storage GO:0019915 1 0.015
internal peptidyl lysine acetylation GO:0018393 2 0.015
nucleocytoplasmic transport GO:0006913 4 0.014
renal system development GO:0072001 94 0.014
centrosome duplication GO:0051298 1 0.014
negative regulation of cellular metabolic process GO:0031324 77 0.014
negative regulation of macromolecule biosynthetic process GO:0010558 48 0.014
lipid homeostasis GO:0055088 3 0.014
regulation of cellular carbohydrate metabolic process GO:0010675 4 0.014
response to organic cyclic compound GO:0014070 51 0.014
response to acid chemical GO:0001101 17 0.014
regulation of tube size GO:0035150 2 0.014
developmental growth GO:0048589 166 0.014
stem cell proliferation GO:0072089 4 0.014
regulation of cytoplasmic transport GO:1903649 4 0.014
macromolecule modification GO:0043412 111 0.013
regulation of protein modification by small protein conjugation or removal GO:1903320 3 0.013
homeostasis of number of cells GO:0048872 62 0.013
negative regulation of rna biosynthetic process GO:1902679 45 0.013
regulation of intracellular protein transport GO:0033157 3 0.013
leukocyte homeostasis GO:0001776 2 0.013
negative regulation of endopeptidase activity GO:0010951 10 0.013
regulation of protein binding GO:0043393 3 0.013
neuron development GO:0048666 262 0.013
cellular protein modification process GO:0006464 100 0.013
kidney development GO:0001822 92 0.013
cellular amino acid biosynthetic process GO:0008652 2 0.013
peptidyl serine modification GO:0018209 2 0.013
positive regulation of response to stimulus GO:0048584 80 0.013
ion transport GO:0006811 114 0.013
monocarboxylic acid metabolic process GO:0032787 17 0.013
regulation of extrinsic apoptotic signaling pathway in absence of ligand GO:2001239 1 0.013
negative regulation of multi organism process GO:0043901 3 0.013
regulation of inflammatory response GO:0050727 2 0.013
regulation of phosphate metabolic process GO:0019220 43 0.013
cellular carbohydrate metabolic process GO:0044262 4 0.013
cilium morphogenesis GO:0060271 85 0.012
negative regulation of multicellular organismal process GO:0051241 69 0.012
positive regulation of immune effector process GO:0002699 3 0.012
response to wounding GO:0009611 116 0.012
regulation of i kappab kinase nf kappab signaling GO:0043122 4 0.012
regulation of protein targeting GO:1903533 2 0.012
intracellular receptor signaling pathway GO:0030522 30 0.012
negative regulation of biosynthetic process GO:0009890 55 0.012
positive regulation of wound healing GO:0090303 1 0.012
regulation of ion transmembrane transporter activity GO:0032412 2 0.012
skeletal system development GO:0001501 181 0.012
protein modification by small protein removal GO:0070646 1 0.012
nucleobase containing compound metabolic process GO:0006139 274 0.012
intrinsic apoptotic signaling pathway in response to oxidative stress GO:0008631 2 0.012
protein import into nucleus GO:0006606 3 0.012
regulation of response to external stimulus GO:0032101 31 0.012
cell projection organization GO:0030030 284 0.012
medulla oblongata development GO:0021550 4 0.012
protein metabolic process GO:0019538 183 0.012
negative regulation of transcription dna templated GO:0045892 45 0.012
mitochondrion organization GO:0007005 4 0.012
hormone secretion GO:0046879 2 0.012
peptidyl serine phosphorylation GO:0018105 1 0.011
regulation of lipid transport GO:0032368 4 0.011
lipid oxidation GO:0034440 1 0.011
protein heterooligomerization GO:0051291 1 0.011
response to external stimulus GO:0009605 264 0.011
response to vitamin GO:0033273 3 0.011
response to vitamin b3 GO:0033552 2 0.011
guanosine containing compound metabolic process GO:1901068 4 0.011
acylglycerol homeostasis GO:0055090 2 0.011
kidney morphogenesis GO:0060993 15 0.011
regulation of carbohydrate metabolic process GO:0006109 4 0.011
negative chemotaxis GO:0050919 1 0.011
regulation of fatty acid metabolic process GO:0019217 1 0.011
negative regulation of intracellular protein transport GO:0090317 3 0.011
multicellular organismal metabolic process GO:0044236 2 0.011
collagen biosynthetic process GO:0032964 2 0.011
regulation of phosphorus metabolic process GO:0051174 43 0.011
establishment of protein localization to organelle GO:0072594 4 0.011
regulation of rho protein signal transduction GO:0035023 2 0.011
phagocytosis engulfment GO:0006911 1 0.011
regulation of receptor activity GO:0010469 2 0.010
histone h3 k4 methylation GO:0051568 2 0.010
i kappab kinase nf kappab signaling GO:0007249 4 0.010
regulation of protein ubiquitination GO:0031396 3 0.010
membrane invagination GO:0010324 1 0.010
cellular response to oxygen containing compound GO:1901701 20 0.010
smooth muscle contraction GO:0006939 2 0.010
negative regulation of developmental process GO:0051093 65 0.010
stem cell maintenance GO:0019827 4 0.010
immune system process GO:0002376 241 0.010
extrinsic apoptotic signaling pathway via death domain receptors GO:0008625 1 0.010
gtp catabolic process GO:0006184 2 0.010
regulation of translational initiation GO:0006446 1 0.010
positive regulation of multi organism process GO:0043902 3 0.010

esd disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
immune system disease DOID:2914 0 0.024
disease of anatomical entity DOID:7 0 0.024
bone marrow disease DOID:4961 0 0.024
hematopoietic system disease DOID:74 0 0.024
nervous system disease DOID:863 0 0.018