Danio rerio

67 known processes

etfa

electron-transfer-flavoprotein, alpha polypeptide

(Aliases: cb1020,wu:fd06h11,fd06h11)

etfa biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
electron transport chain GO:0022900 2 0.834
respiratory electron transport chain GO:0022904 2 0.665
larval development GO:0002164 2 0.626
Worm
cellular respiration GO:0045333 3 0.617
aging GO:0007568 2 0.590
organic acid catabolic process GO:0016054 3 0.402
macromolecule biosynthetic process GO:0009059 227 0.395
mitochondrial atp synthesis coupled electron transport GO:0042775 1 0.377
atp synthesis coupled electron transport GO:0042773 1 0.366
establishment of localization GO:0051234 244 0.334
response to chemical GO:0042221 320 0.327
cellular aromatic compound metabolic process GO:0006725 295 0.250
nitrogen compound metabolic process GO:0006807 319 0.249
myeloid cell differentiation GO:0030099 86 0.248
cellular nitrogen compound metabolic process GO:0034641 290 0.239
oxidative phosphorylation GO:0006119 1 0.192
regulation of cellular biosynthetic process GO:0031326 245 0.176
generation of precursor metabolites and energy GO:0006091 5 0.169
response to organic substance GO:0010033 153 0.164
cellular macromolecule biosynthetic process GO:0034645 224 0.162
hydrogen peroxide metabolic process GO:0042743 2 0.158
purine nucleotide metabolic process GO:0006163 27 0.155
central nervous system development GO:0007417 387 0.153
oxoacid metabolic process GO:0043436 31 0.151
cellular biosynthetic process GO:0044249 286 0.150
organic acid metabolic process GO:0006082 31 0.148
carboxylic acid catabolic process GO:0046395 3 0.138
cellular lipid metabolic process GO:0044255 36 0.128
response to drug GO:0042493 3 0.119
single organism localization GO:1902578 225 0.118
organic substance biosynthetic process GO:1901576 289 0.113
regulation of cellular metabolic process GO:0031323 320 0.099
heterocycle metabolic process GO:0046483 290 0.098
nucleobase containing compound metabolic process GO:0006139 274 0.097
organic cyclic compound metabolic process GO:1901360 301 0.090
transport GO:0006810 220 0.087
small molecule metabolic process GO:0044281 77 0.084
negative regulation of kinase activity GO:0033673 4 0.082
negative regulation of biological process GO:0048519 304 0.080
signal transduction GO:0007165 455 0.080
multicellular organism growth GO:0035264 4 0.079
nucleic acid metabolic process GO:0090304 244 0.079
single organism metabolic process GO:0044710 217 0.078
immune system development GO:0002520 191 0.076
regulation of stem cell proliferation GO:0072091 2 0.075
cell surface receptor signaling pathway GO:0007166 325 0.074
locomotion GO:0040011 313 0.072
ion transmembrane transport GO:0034220 91 0.071
growth GO:0040007 174 0.071
mitochondrion organization GO:0007005 4 0.070
nucleoside monophosphate metabolic process GO:0009123 6 0.069
cellular macromolecule metabolic process GO:0044260 391 0.067
pyruvate metabolic process GO:0006090 1 0.065
cellular response to chemical stimulus GO:0070887 157 0.065
carboxylic acid metabolic process GO:0019752 22 0.065
lipid storage GO:0019915 1 0.065
regulation of neural precursor cell proliferation GO:2000177 3 0.064
alpha amino acid metabolic process GO:1901605 3 0.062
regulation of multicellular organism growth GO:0040014 4 0.058
regulation of oligodendrocyte differentiation GO:0048713 1 0.058
cellular nitrogen compound biosynthetic process GO:0044271 218 0.057
regulation of gene expression GO:0010468 265 0.054
single organism organelle organization GO:1902589 199 0.054
acetyl coa metabolic process GO:0006084 1 0.054
negative regulation of neural precursor cell proliferation GO:2000178 1 0.053
nucleobase containing small molecule metabolic process GO:0055086 32 0.052
cellular localization GO:0051641 97 0.052
cell part morphogenesis GO:0032990 246 0.050
embryo development ending in birth or egg hatching GO:0009792 271 0.049
Worm Fly
organelle organization GO:0006996 227 0.049
biosynthetic process GO:0009058 294 0.047
response to oxygen levels GO:0070482 25 0.047
oxidation reduction process GO:0055114 41 0.045
phosphorus metabolic process GO:0006793 109 0.045
regulation of biosynthetic process GO:0009889 250 0.044
negative regulation of signaling GO:0023057 96 0.044
negative regulation of gene expression GO:0010629 65 0.043
negative regulation of tor signaling GO:0032007 2 0.043
transmembrane transport GO:0055085 120 0.042
determination of left right symmetry GO:0007368 179 0.042
immune system process GO:0002376 241 0.041
small molecule catabolic process GO:0044282 3 0.041
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.040
branched chain amino acid metabolic process GO:0009081 1 0.040
regulation of rna biosynthetic process GO:2001141 213 0.039
neuroblast proliferation GO:0007405 2 0.038
hematopoietic or lymphoid organ development GO:0048534 191 0.038
developmental growth GO:0048589 166 0.038
cellular component biogenesis GO:0044085 178 0.037
regulation of biological quality GO:0065008 263 0.037
energy derivation by oxidation of organic compounds GO:0015980 5 0.037
organophosphate metabolic process GO:0019637 37 0.037
regulation of primary metabolic process GO:0080090 311 0.036
cellular response to hypoxia GO:0071456 1 0.035
cellular component movement GO:0006928 335 0.035
stem cell proliferation GO:0072089 4 0.035
cellular response to oxygen levels GO:0071453 1 0.034
cellular response to decreased oxygen levels GO:0036294 1 0.034
negative regulation of signal transduction GO:0009968 94 0.034
carbohydrate derivative metabolic process GO:1901135 61 0.034
heterocycle biosynthetic process GO:0018130 215 0.033
tissue regeneration GO:0042246 74 0.033
head development GO:0060322 303 0.033
dicarboxylic acid metabolic process GO:0043648 1 0.033
regulation of nucleoside metabolic process GO:0009118 2 0.032
response to external stimulus GO:0009605 264 0.032
regulation of signaling GO:0023051 235 0.032
response to hypoxia GO:0001666 25 0.032
hemoglobin metabolic process GO:0020027 12 0.032
mitochondrial transport GO:0006839 2 0.031
gene expression GO:0010467 252 0.031
transcription dna templated GO:0006351 181 0.031
regulation of blood pressure GO:0008217 1 0.031
cell motility GO:0048870 244 0.031
organonitrogen compound metabolic process GO:1901564 74 0.031
nucleic acid templated transcription GO:0097659 181 0.030
regulation of metabolic process GO:0019222 359 0.030
regulation of blood vessel size GO:0050880 2 0.030
ribonucleotide metabolic process GO:0009259 27 0.030
phosphate containing compound metabolic process GO:0006796 108 0.029
digestive tract development GO:0048565 265 0.029
Fly
histone deacetylation GO:0016575 2 0.028
homeostasis of number of cells GO:0048872 62 0.028
cellular amino acid biosynthetic process GO:0008652 2 0.027
tor signaling GO:0031929 7 0.026
regulation of multicellular organismal process GO:0051239 277 0.025
aromatic compound biosynthetic process GO:0019438 217 0.025
negative regulation of cell communication GO:0010648 96 0.025
liver development GO:0001889 96 0.025
hemopoiesis GO:0030097 183 0.025
negative regulation of cellular process GO:0048523 283 0.025
embryonic heart tube development GO:0035050 133 0.025
wound healing GO:0042060 90 0.025
purine ribonucleotide metabolic process GO:0009150 27 0.024
protein complex biogenesis GO:0070271 30 0.024
system process GO:0003008 185 0.024
response to glucocorticoid GO:0051384 1 0.024
organic anion transport GO:0015711 15 0.024
regulation of membrane potential GO:0042391 23 0.024
regeneration GO:0031099 91 0.024
regulation of macromolecule metabolic process GO:0060255 317 0.024
cellular component assembly GO:0022607 170 0.023
cation transmembrane transport GO:0098655 65 0.023
anion transport GO:0006820 38 0.023
mitochondrion morphogenesis GO:0070584 2 0.023
regulation of nitrogen compound metabolic process GO:0051171 251 0.023
regulation of signal transduction GO:0009966 225 0.023
cellular response to topologically incorrect protein GO:0035967 2 0.023
meiotic cell cycle process GO:1903046 3 0.022
organelle assembly GO:0070925 110 0.022
determination of bilateral symmetry GO:0009855 204 0.022
response to oxidative stress GO:0006979 11 0.022
regulation of cellular amine metabolic process GO:0033238 0 0.022
response to unfolded protein GO:0006986 2 0.022
specification of symmetry GO:0009799 204 0.022
nucleotide metabolic process GO:0009117 28 0.022
cellular response to reactive oxygen species GO:0034614 2 0.021
embryonic organ development GO:0048568 381 0.021
leukocyte proliferation GO:0070661 1 0.021
cellular amino acid metabolic process GO:0006520 7 0.021
coenzyme metabolic process GO:0006732 5 0.021
er nucleus signaling pathway GO:0006984 2 0.021
negative regulation of developmental process GO:0051093 65 0.021
regulation of carbohydrate metabolic process GO:0006109 4 0.021
embryonic organ morphogenesis GO:0048562 274 0.021
amine metabolic process GO:0009308 2 0.021
meiotic nuclear division GO:0007126 4 0.020
cognition GO:0050890 1 0.020
cellular protein modification process GO:0006464 100 0.020
organic acid transport GO:0015849 9 0.020
dicarboxylic acid transport GO:0006835 1 0.020
regulation of developmental process GO:0050793 247 0.020
adult behavior GO:0030534 2 0.020
response to wounding GO:0009611 116 0.020
generation of neurons GO:0048699 385 0.020
behavior GO:0007610 74 0.020
inorganic cation transmembrane transport GO:0098662 50 0.019
regulation of developmental growth GO:0048638 38 0.019
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.019
regulation of cardiac muscle tissue development GO:0055024 1 0.019
intracellular receptor signaling pathway GO:0030522 30 0.019
cellular amine metabolic process GO:0044106 2 0.019
single organism transport GO:0044765 206 0.018
brain development GO:0007420 293 0.018
regulation of behavior GO:0050795 24 0.018
signal transduction in absence of ligand GO:0038034 1 0.018
anion transmembrane transport GO:0098656 12 0.018
negative regulation of oxidative stress induced intrinsic apoptotic signaling pathway GO:1902176 2 0.018
myofibril assembly GO:0030239 48 0.018
morphogenesis of an epithelium GO:0002009 333 0.018
Fly
catabolic process GO:0009056 32 0.018
organic cyclic compound biosynthetic process GO:1901362 223 0.018
cellular carbohydrate metabolic process GO:0044262 4 0.017
cellular component morphogenesis GO:0032989 336 0.017
establishment of protein localization to organelle GO:0072594 4 0.017
cellular response to organic substance GO:0071310 105 0.017
spindle assembly involved in mitosis GO:0090307 1 0.017
regulation of response to stimulus GO:0048583 269 0.017
heme metabolic process GO:0042168 9 0.017
chordate embryonic development GO:0043009 271 0.017
carboxylic acid transport GO:0046942 8 0.017
neurotransmitter transport GO:0006836 2 0.016
regulation of rac protein signal transduction GO:0035020 1 0.016
maintenance of location GO:0051235 4 0.016
regulation of multicellular organismal development GO:2000026 223 0.016
mesenchymal cell development GO:0014031 78 0.016
rna biosynthetic process GO:0032774 181 0.016
single organism biosynthetic process GO:0044711 71 0.016
purine nucleoside monophosphate metabolic process GO:0009126 5 0.016
endoplasmic reticulum unfolded protein response GO:0030968 2 0.016
negative regulation of neurogenesis GO:0050768 20 0.015
negative regulation of multicellular organismal process GO:0051241 69 0.015
gene silencing by rna GO:0031047 4 0.015
regulation of epithelial cell proliferation GO:0050678 3 0.015
response to hydrogen peroxide GO:0042542 3 0.015
erythrocyte differentiation GO:0030218 54 0.015
organonitrogen compound biosynthetic process GO:1901566 47 0.015
negative regulation of protein kinase activity GO:0006469 4 0.015
response to stress GO:0006950 263 0.014
protein import GO:0017038 3 0.014
striated muscle tissue development GO:0014706 110 0.014
cellular lipid catabolic process GO:0044242 3 0.014
protein metabolic process GO:0019538 183 0.014
negative regulation of protein transport GO:0051224 3 0.014
osteoclast differentiation GO:0030316 1 0.014
negative regulation of response to stimulus GO:0048585 104 0.014
protein acylation GO:0043543 3 0.014
peptide transport GO:0015833 1 0.014
digestive system development GO:0055123 289 0.014
Fly
regulation of dna replication GO:0006275 3 0.014
intestinal epithelial cell differentiation GO:0060575 3 0.014
response to hormone GO:0009725 48 0.013
response to decreased oxygen levels GO:0036293 25 0.013
mitochondrial electron transport nadh to ubiquinone GO:0006120 1 0.013
regulation of protein localization to nucleus GO:1900180 2 0.013
purine containing compound metabolic process GO:0072521 29 0.013
cell projection organization GO:0030030 284 0.013
locomotory behavior GO:0007626 34 0.013
positive regulation of leukocyte differentiation GO:1902107 1 0.013
establishment of localization in cell GO:0051649 77 0.013
protein complex assembly GO:0006461 30 0.013
multicellular organismal metabolic process GO:0044236 2 0.013
positive regulation of cell activation GO:0050867 1 0.013
positive regulation of cellular amine metabolic process GO:0033240 0 0.013
negative regulation of protein localization to nucleus GO:1900181 2 0.013
regulation of gene expression epigenetic GO:0040029 11 0.013
positive regulation of stem cell proliferation GO:2000648 1 0.013
positive regulation of gene expression GO:0010628 71 0.012
purine nucleoside monophosphate catabolic process GO:0009128 4 0.012
leukocyte differentiation GO:0002521 25 0.012
columnar cuboidal epithelial cell differentiation GO:0002065 38 0.012
regulation of endothelial cell proliferation GO:0001936 1 0.012
erythrocyte homeostasis GO:0034101 55 0.012
regulation of macromolecule biosynthetic process GO:0010556 225 0.012
negative regulation of metabolic process GO:0009892 86 0.012
macromolecular complex subunit organization GO:0043933 74 0.012
positive regulation of cellular carbohydrate metabolic process GO:0010676 1 0.012
stem cell development GO:0048864 82 0.012
fin regeneration GO:0031101 51 0.012
response to abiotic stimulus GO:0009628 122 0.012
alcohol biosynthetic process GO:0046165 2 0.011
regulation of cellular ketone metabolic process GO:0010565 7 0.011
hemoglobin biosynthetic process GO:0042541 8 0.011
camera type eye development GO:0043010 222 0.011
cell substrate adhesion GO:0031589 4 0.011
protein secretion GO:0009306 1 0.011
regulation of glial cell differentiation GO:0045685 4 0.011
protein homooligomerization GO:0051260 3 0.011
mesenchyme development GO:0060485 127 0.011
negative regulation of dna metabolic process GO:0051053 4 0.011
phagocytosis engulfment GO:0006911 1 0.011
response to corticosteroid GO:0031960 1 0.011
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.011
regulation of autophagy GO:0010506 3 0.011
regulation of rna metabolic process GO:0051252 224 0.011
regulation of cellular amino acid metabolic process GO:0006521 0 0.011
posttranscriptional gene silencing by rna GO:0035194 3 0.011
iron ion homeostasis GO:0055072 4 0.011
muscle tissue development GO:0060537 110 0.011
determination of heart left right asymmetry GO:0061371 117 0.011
response to external biotic stimulus GO:0043207 97 0.011
mesenchymal cell differentiation GO:0048762 87 0.011
regulation of growth GO:0040008 42 0.011
single organism behavior GO:0044708 24 0.011
macromolecule modification GO:0043412 111 0.011
nuclear transport GO:0051169 4 0.010
positive regulation of nucleoside metabolic process GO:0045979 1 0.010
fatty acid catabolic process GO:0009062 1 0.010
brain morphogenesis GO:0048854 18 0.010
internal protein amino acid acetylation GO:0006475 2 0.010
posttranscriptional gene silencing GO:0016441 3 0.010
cell morphogenesis GO:0000902 289 0.010
cofactor metabolic process GO:0051186 15 0.010
tissue remodeling GO:0048771 4 0.010
regulation of cardiac muscle cell contraction GO:0086004 1 0.010
lipid catabolic process GO:0016042 4 0.010
cellular ketone metabolic process GO:0042180 11 0.010

etfa disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 0 0.188
mitochondrial metabolism disease DOID:700 0 0.188
inherited metabolic disorder DOID:655 0 0.188
cancer DOID:162 0 0.032
disease of cellular proliferation DOID:14566 0 0.032
myopathy DOID:423 0 0.025
muscular disease DOID:0080000 0 0.025
heart disease DOID:114 0 0.025
cardiomyopathy DOID:0050700 0 0.025
disease of anatomical entity DOID:7 0 0.025
cardiovascular system disease DOID:1287 0 0.025
musculoskeletal system disease DOID:17 0 0.025
muscle tissue disease DOID:66 0 0.025
thoracic cancer DOID:5093 0 0.022
organ system cancer DOID:0050686 0 0.022
intrinsic cardiomyopathy DOID:0060036 0 0.019
endocrine gland cancer DOID:170 0 0.019
nervous system disease DOID:863 0 0.016
leigh disease DOID:3652 0 0.016
amino acid metabolic disorder DOID:9252 0 0.012