Danio rerio

0 known processes

evla

Enah/Vasp-like a

(Aliases: id:ibd2260,Evl,zgc:65883,zgc:77388)

evla biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
generation of neurons GO:0048699 385 0.318
Worm Fly
neuron differentiation GO:0030182 353 0.180
Worm Fly
cell part morphogenesis GO:0032990 246 0.123
Worm Fly
meiosis i GO:0007127 1 0.116
immune system process GO:0002376 241 0.111
organelle organization GO:0006996 227 0.102
Human Mouse Fly
cellular component morphogenesis GO:0032989 336 0.092
Worm Fly
meiotic cell cycle process GO:1903046 3 0.091
meiotic nuclear division GO:0007126 4 0.091
cytoskeleton organization GO:0007010 96 0.087
Human Mouse Fly
larval development GO:0002164 2 0.087
glycoprotein biosynthetic process GO:0009101 21 0.084
regulation of reproductive process GO:2000241 4 0.083
aging GO:0007568 2 0.072
regulation of cell communication GO:0010646 232 0.068
Zebrafish
neuron development GO:0048666 262 0.066
Worm Fly
cell projection morphogenesis GO:0048858 244 0.064
Worm Fly
digestive system development GO:0055123 289 0.063
single organism nuclear import GO:1902593 3 0.063
proteasomal protein catabolic process GO:0010498 2 0.062
cellular macromolecule biosynthetic process GO:0034645 224 0.057
single organism organelle organization GO:1902589 199 0.057
Human Mouse Fly
leukocyte proliferation GO:0070661 1 0.056
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.052
cellular nitrogen compound metabolic process GO:0034641 290 0.052
protein localization to plasma membrane GO:0072659 1 0.051
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.050
Worm Fly
cell projection organization GO:0030030 284 0.048
Human Worm Fly
phagocytosis engulfment GO:0006911 1 0.048
multicellular organismal metabolic process GO:0044236 2 0.048
maintenance of location GO:0051235 4 0.047
protein import into nucleus GO:0006606 3 0.047
response to drug GO:0042493 3 0.046
regulation of membrane potential GO:0042391 23 0.045
cellular protein catabolic process GO:0044257 4 0.044
protein targeting to nucleus GO:0044744 3 0.043
morphogenesis of an epithelium GO:0002009 333 0.042
Fly
multicellular organism growth GO:0035264 4 0.042
mitochondrion organization GO:0007005 4 0.042
lipid storage GO:0019915 1 0.041
death GO:0016265 121 0.040
cellular macromolecule metabolic process GO:0044260 391 0.040
regulation of biological quality GO:0065008 263 0.039
Mouse Fly
nuclear import GO:0051170 3 0.039
hepaticobiliary system development GO:0061008 98 0.039
multicellular organismal signaling GO:0035637 22 0.038
macromolecular complex subunit organization GO:0043933 74 0.038
Human Mouse Fly
cellular protein metabolic process GO:0044267 129 0.038
mononuclear cell proliferation GO:0032943 1 0.038
neuron projection development GO:0031175 180 0.037
Worm Fly
regulation of response to stimulus GO:0048583 269 0.037
Zebrafish
nucleobase containing compound metabolic process GO:0006139 274 0.036
inner ear development GO:0048839 126 0.036
ear development GO:0043583 127 0.036
positive regulation of macromolecule metabolic process GO:0010604 93 0.035
gtp metabolic process GO:0046039 4 0.035
regulation of multicellular organismal development GO:2000026 223 0.035
Fly
adult behavior GO:0030534 2 0.035
protein metabolic process GO:0019538 183 0.034
muscle structure development GO:0061061 196 0.034
signal transduction GO:0007165 455 0.034
Zebrafish
gtp catabolic process GO:0006184 2 0.034
single fertilization GO:0007338 3 0.033
regulation of signaling GO:0023051 235 0.033
Zebrafish
tube morphogenesis GO:0035239 349 0.033
dna templated transcription elongation GO:0006354 3 0.033
cellular component assembly involved in morphogenesis GO:0010927 107 0.033
guanosine containing compound metabolic process GO:1901068 4 0.033
phagocytosis GO:0006909 3 0.033
locomotion GO:0040011 313 0.033
Human Worm Fly
nucleocytoplasmic transport GO:0006913 4 0.032
modification dependent macromolecule catabolic process GO:0043632 3 0.032
cell motility GO:0048870 244 0.032
Human Worm Fly
ubiquitin dependent protein catabolic process GO:0006511 3 0.032
regulation of striated muscle contraction GO:0006942 2 0.031
oocyte anterior posterior axis specification GO:0007314 4 0.031
cell death GO:0008219 121 0.031
regulation of establishment of protein localization GO:0070201 4 0.031
modification dependent protein catabolic process GO:0019941 3 0.030
regulation of protein transport GO:0051223 3 0.030
response to biotic stimulus GO:0009607 97 0.030
organonitrogen compound metabolic process GO:1901564 74 0.030
guanosine containing compound catabolic process GO:1901069 2 0.030
regulation of protein catabolic process GO:0042176 1 0.030
regulation of intracellular protein transport GO:0033157 3 0.029
nitrogen compound metabolic process GO:0006807 319 0.029
phosphorus metabolic process GO:0006793 109 0.029
single organism localization GO:1902578 225 0.029
Fly
regulation of cell activation GO:0050865 1 0.029
sensory organ development GO:0007423 393 0.029
Fly
regulation of signal transduction GO:0009966 225 0.029
Zebrafish
cellular localization GO:0051641 97 0.029
Fly
muscle cell differentiation GO:0042692 139 0.029
cell migration GO:0016477 237 0.028
Human Worm Fly
circulatory system process GO:0003013 87 0.028
negative regulation of biological process GO:0048519 304 0.028
Human Fly
positive regulation of catabolic process GO:0009896 4 0.028
regulation of ion transmembrane transporter activity GO:0032412 2 0.028
positive regulation of transport GO:0051050 2 0.028
cellular component movement GO:0006928 335 0.028
Human Worm Fly
hatching gland development GO:0048785 3 0.028
embryo development ending in birth or egg hatching GO:0009792 271 0.028
Fly
regulation of multicellular organism growth GO:0040014 4 0.027
neuron projection morphogenesis GO:0048812 161 0.027
Worm Fly
phosphate containing compound metabolic process GO:0006796 108 0.027
regulation of muscle contraction GO:0006937 3 0.027
regulation of reactive oxygen species metabolic process GO:2000377 2 0.027
cell morphogenesis GO:0000902 289 0.027
Worm Fly
axis specification GO:0009798 43 0.026
axonogenesis GO:0007409 152 0.026
Worm Fly
cellular response to starvation GO:0009267 1 0.026
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.026
cell morphogenesis involved in differentiation GO:0000904 195 0.025
Worm Fly
regulation of cell shape GO:0008360 1 0.025
Fly
maternal determination of anterior posterior axis embryo GO:0008358 4 0.025
peptide metabolic process GO:0006518 1 0.025
multi organism process GO:0051704 134 0.025
Fly
semicircular canal development GO:0060872 24 0.025
organic substance biosynthetic process GO:1901576 289 0.025
protein localization to nucleus GO:0034504 3 0.024
regulation of anatomical structure morphogenesis GO:0022603 130 0.024
Fly
positive regulation of metabolic process GO:0009893 108 0.024
positive regulation of gene expression GO:0010628 71 0.024
blood circulation GO:0008015 87 0.024
cellular monovalent inorganic cation homeostasis GO:0030004 2 0.024
cellular biosynthetic process GO:0044249 286 0.024
localization of cell GO:0051674 244 0.023
Human Worm Fly
hematopoietic or lymphoid organ development GO:0048534 191 0.023
fertilization GO:0009566 3 0.023
wound healing GO:0042060 90 0.023
cellular component assembly GO:0022607 170 0.023
Human Mouse Fly
ventricular cardiac muscle tissue development GO:0003229 3 0.023
digestive tract development GO:0048565 265 0.023
response to external biotic stimulus GO:0043207 97 0.023
carbohydrate derivative metabolic process GO:1901135 61 0.023
growth GO:0040007 174 0.023
Fly
regulation of cytoplasmic transport GO:1903649 4 0.023
regulation of transcription elongation from rna polymerase ii promoter GO:0034243 3 0.022
myeloid cell differentiation GO:0030099 86 0.022
cytokinesis GO:0000910 3 0.022
eye development GO:0001654 277 0.022
Fly
regulation of nucleocytoplasmic transport GO:0046822 2 0.022
regulation of apoptotic process GO:0042981 98 0.021
spermatid differentiation GO:0048515 2 0.021
apoptotic process GO:0006915 116 0.021
transcription dna templated GO:0006351 181 0.021
regulation of cell death GO:0010941 103 0.021
protein modification process GO:0036211 100 0.021
single organism metabolic process GO:0044710 217 0.021
cellular response to extracellular stimulus GO:0031668 2 0.021
cardiac conduction GO:0061337 3 0.021
regulation of purine nucleotide catabolic process GO:0033121 2 0.021
heterocycle metabolic process GO:0046483 290 0.021
glycosylation GO:0070085 11 0.020
positive regulation of nucleoside metabolic process GO:0045979 1 0.020
negative regulation of reproductive process GO:2000242 3 0.020
reproduction GO:0000003 40 0.020
Fly
cellular response to oxygen levels GO:0071453 1 0.020
reactive nitrogen species metabolic process GO:2001057 0 0.020
regeneration GO:0031099 91 0.020
Worm
gastrulation GO:0007369 208 0.020
cellular response to nutrient levels GO:0031669 2 0.020
nuclear transport GO:0051169 4 0.020
protein import GO:0017038 3 0.020
reactive oxygen species biosynthetic process GO:1903409 1 0.020
membrane invagination GO:0010324 1 0.020
regulation of nervous system development GO:0051960 90 0.019
Fly
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.019
actin polymerization or depolymerization GO:0008154 2 0.019
Mouse
transport GO:0006810 220 0.019
Fly
establishment of localization in cell GO:0051649 77 0.019
Fly
positive regulation of cellular catabolic process GO:0031331 3 0.019
regulation of dna templated transcription elongation GO:0032784 3 0.019
regulation of cell development GO:0060284 100 0.019
cell cell recognition GO:0009988 1 0.019
cell proliferation GO:0008283 80 0.019
transcription elongation from rna polymerase ii promoter GO:0006368 3 0.019
rna localization GO:0006403 4 0.019
ventricular cardiac muscle tissue morphogenesis GO:0055010 2 0.019
regulation of tube size GO:0035150 2 0.019
membrane organization GO:0061024 21 0.018
hemopoiesis GO:0030097 183 0.018
cellular amino acid metabolic process GO:0006520 7 0.018
single organism transport GO:0044765 206 0.018
Fly
erythrocyte homeostasis GO:0034101 55 0.018
startle response GO:0001964 4 0.018
nitric oxide metabolic process GO:0046209 2 0.018
nuclear export GO:0051168 1 0.018
action potential GO:0001508 19 0.018
lymphocyte proliferation GO:0046651 1 0.018
positive regulation of apoptotic signaling pathway GO:2001235 1 0.018
autophagy GO:0006914 4 0.018
positive regulation of cell cycle GO:0045787 3 0.018
organelle assembly GO:0070925 110 0.018
regulation of system process GO:0044057 40 0.018
response to stress GO:0006950 263 0.018
Worm
convergent extension GO:0060026 118 0.018
macromolecule biosynthetic process GO:0009059 227 0.017
axon development GO:0061564 166 0.017
Worm Fly
macromolecule modification GO:0043412 111 0.017
biosynthetic process GO:0009058 294 0.017
endoderm development GO:0007492 49 0.017
regulation of transmembrane transporter activity GO:0022898 2 0.017
cellular aromatic compound metabolic process GO:0006725 295 0.017
protein polymerization GO:0051258 4 0.017
Mouse
positive regulation of nucleotide catabolic process GO:0030813 1 0.017
cellular response to external stimulus GO:0071496 2 0.017
regulation of protein localization to nucleus GO:1900180 2 0.017
cytoplasm organization GO:0007028 4 0.017
organic cyclic compound metabolic process GO:1901360 301 0.017
cranial nerve development GO:0021545 42 0.017
regulation of nucleotide catabolic process GO:0030811 2 0.017
cellular component disassembly GO:0022411 1 0.017
cellular component biogenesis GO:0044085 178 0.017
Human Mouse Fly
epithelial cell differentiation GO:0030855 116 0.016
Fly
regulation of cardiac muscle contraction GO:0055117 2 0.016
pole plasm assembly GO:0007315 4 0.016
single organism reproductive process GO:0044702 40 0.016
Fly
developmental growth GO:0048589 166 0.016
Fly
regulation of rho protein signal transduction GO:0035023 2 0.016
neuronal action potential GO:0019228 18 0.016
regulation of multicellular organismal process GO:0051239 277 0.016
Human Fly
oxoacid metabolic process GO:0043436 31 0.016
positive regulation of biological process GO:0048518 253 0.016
Human Mouse Fly
actin filament based process GO:0030029 64 0.016
Human Mouse Fly
regulation of developmental process GO:0050793 247 0.016
Fly
alternative mrna splicing via spliceosome GO:0000380 1 0.016
programmed cell death GO:0012501 119 0.016
positive regulation of purine nucleotide catabolic process GO:0033123 1 0.015
positive regulation of immune effector process GO:0002699 3 0.015
regulation of nucleoside metabolic process GO:0009118 2 0.015
response to ketone GO:1901654 1 0.015
anatomical structure arrangement GO:0048532 2 0.015
regulation of cellular amino acid metabolic process GO:0006521 0 0.015
regulation of protein metabolic process GO:0051246 56 0.015
establishment of endothelial barrier GO:0061028 3 0.015
neuron projection guidance GO:0097485 86 0.015
Worm Fly
production of molecular mediator of immune response GO:0002440 2 0.015
regulation of production of molecular mediator of immune response GO:0002700 1 0.015
regulation of intracellular ph GO:0051453 1 0.015
multicellular organismal reproductive process GO:0048609 35 0.015
Fly
cell cycle g1 s phase transition GO:0044843 1 0.015
cellular ketone metabolic process GO:0042180 11 0.015
stem cell fate commitment GO:0048865 1 0.015
response to corticosteroid GO:0031960 1 0.015
regulation of protein targeting GO:1903533 2 0.015
sensory organ morphogenesis GO:0090596 200 0.015
post embryonic organ development GO:0048569 4 0.015
establishment of protein localization to organelle GO:0072594 4 0.014
embryonic organ development GO:0048568 381 0.014
cellular amide metabolic process GO:0043603 4 0.014
negative regulation of ras protein signal transduction GO:0046580 1 0.014
nitric oxide biosynthetic process GO:0006809 2 0.014
sexual reproduction GO:0019953 36 0.014
Fly
organic acid metabolic process GO:0006082 31 0.014
positive regulation of cell activation GO:0050867 1 0.014
regulation of cellular metabolic process GO:0031323 320 0.014
regulation of response to biotic stimulus GO:0002831 2 0.014
head development GO:0060322 303 0.014
lipid homeostasis GO:0055088 3 0.014
spermatid development GO:0007286 2 0.014
regionalization GO:0003002 274 0.014
Fly
tissue regeneration GO:0042246 74 0.014
protein targeting to membrane GO:0006612 1 0.014
epithelial tube morphogenesis GO:0060562 148 0.014
ribonucleoside monophosphate catabolic process GO:0009158 4 0.013
regulation of cell differentiation GO:0045595 142 0.013
carboxylic acid metabolic process GO:0019752 22 0.013
positive regulation of cellular metabolic process GO:0031325 94 0.013
homeostatic process GO:0042592 142 0.013
heart contraction GO:0060047 71 0.013
regulation of cellular ph GO:0030641 1 0.013
phosphorylation GO:0016310 69 0.013
regulation of gtp catabolic process GO:0033124 2 0.013
positive regulation of transcription elongation from rna polymerase ii promoter GO:0032968 1 0.013
regulation of nucleic acid templated transcription GO:1903506 213 0.013
blood vessel morphogenesis GO:0048514 216 0.013
Zebrafish
regulation of erk1 and erk2 cascade GO:0070372 4 0.013
defense response to fungus GO:0050832 2 0.013
glycoprotein metabolic process GO:0009100 23 0.013
proximal distal pattern formation GO:0009954 1 0.013
extrinsic apoptotic signaling pathway GO:0097191 3 0.013
reproductive process GO:0022414 40 0.013
Fly
b cell activation GO:0042113 2 0.013
cell surface receptor signaling pathway GO:0007166 325 0.013
Zebrafish
endoderm formation GO:0001706 29 0.013
collagen metabolic process GO:0032963 2 0.013
defense response GO:0006952 47 0.013
cortical actin cytoskeleton organization GO:0030866 1 0.013
transcription from rna polymerase ii promoter GO:0006366 80 0.013
regulation of gene expression GO:0010468 265 0.013
regulation of blood vessel size GO:0050880 2 0.013
negative regulation of signal transduction GO:0009968 94 0.013
regulation of cellular amine metabolic process GO:0033238 0 0.013
negative regulation of cytokine production GO:0001818 1 0.013
multicellular organismal macromolecule metabolic process GO:0044259 2 0.012
nucleic acid templated transcription GO:0097659 181 0.012
enzyme linked receptor protein signaling pathway GO:0007167 106 0.012
Zebrafish
regulation of cellular ketone metabolic process GO:0010565 7 0.012
regulation of protein modification by small protein conjugation or removal GO:1903320 3 0.012
female gonad development GO:0008585 4 0.012
meiotic chromosome segregation GO:0045132 3 0.012
anterior posterior pattern specification GO:0009952 152 0.012
Fly
response to other organism GO:0051707 97 0.012
positive regulation of gtpase activity GO:0043547 1 0.012
regulation of ph GO:0006885 3 0.012
amine metabolic process GO:0009308 2 0.012
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 2 0.012
negative regulation of cellular catabolic process GO:0031330 3 0.012
regulation of dendrite development GO:0050773 3 0.012
regulation of protein complex assembly GO:0043254 3 0.012
Mouse
regulation of programmed cell death GO:0043067 101 0.012
stem cell maintenance GO:0019827 4 0.012
negative regulation of autophagy GO:0010507 1 0.012
hindbrain development GO:0030902 91 0.012
response to glucocorticoid GO:0051384 1 0.012
camera type eye morphogenesis GO:0048593 108 0.012
positive regulation of canonical wnt signaling pathway GO:0090263 4 0.012
rhombomere 5 development GO:0021571 4 0.012
regulation of protein polymerization GO:0032271 2 0.012
Mouse
purine ribonucleoside monophosphate catabolic process GO:0009169 4 0.012
symbiosis encompassing mutualism through parasitism GO:0044403 4 0.012
regulation of autophagy GO:0010506 3 0.012
positive regulation of dna templated transcription elongation GO:0032786 1 0.012
multicellular organism reproduction GO:0032504 35 0.011
Fly
negative regulation of multi organism process GO:0043901 3 0.011
skeletal system morphogenesis GO:0048705 102 0.011
regulation of gtpase activity GO:0043087 2 0.011
regulation of microtubule cytoskeleton organization GO:0070507 3 0.011
astrocyte differentiation GO:0048708 1 0.011
rna metabolic process GO:0016070 219 0.011
stem cell proliferation GO:0072089 4 0.011
determination of left right symmetry GO:0007368 179 0.011
regulation of molecular function GO:0065009 70 0.011
regulation of catalytic activity GO:0050790 55 0.011
regulation of myotube differentiation GO:0010830 2 0.011
small molecule metabolic process GO:0044281 77 0.011
antimicrobial humoral response GO:0019730 2 0.011
regulation of protein import into nucleus GO:0042306 2 0.011
protein complex disassembly GO:0043241 1 0.011
transmission of nerve impulse GO:0019226 19 0.011
nucleobase containing compound biosynthetic process GO:0034654 205 0.011
protein stabilization GO:0050821 2 0.011
positive regulation of multi organism process GO:0043902 3 0.011
cellular protein modification process GO:0006464 100 0.011
estrogen metabolic process GO:0008210 2 0.011
protein phosphorylation GO:0006468 47 0.011
regulation of cytokine production GO:0001817 3 0.011
heart development GO:0007507 313 0.011
regulation of ras gtpase activity GO:0032318 2 0.011
cognition GO:0050890 1 0.011
regulation of ectodermal cell fate specification GO:0042665 2 0.011
regulation of cellular biosynthetic process GO:0031326 245 0.011
microtubule organizing center organization GO:0031023 1 0.011
determination of heart left right asymmetry GO:0061371 117 0.011
negative regulation of developmental process GO:0051093 65 0.011
Fly
immunoglobulin mediated immune response GO:0016064 3 0.011
immune system development GO:0002520 191 0.011
system process GO:0003008 185 0.011
cellular amine metabolic process GO:0044106 2 0.011
cilium morphogenesis GO:0060271 85 0.011
regulation of macromolecule biosynthetic process GO:0010556 225 0.011
protein homooligomerization GO:0051260 3 0.011
positive regulation of cytokine production GO:0001819 2 0.011
axon ensheathment GO:0008366 18 0.010
regulation of synapse assembly GO:0051963 3 0.010
Fly
neuroblast differentiation GO:0014016 1 0.010
negative regulation of protein phosphorylation GO:0001933 4 0.010
positive regulation of gtp catabolic process GO:0033126 1 0.010
cytoskeleton dependent cytokinesis GO:0061640 3 0.010
centrosome cycle GO:0007098 1 0.010
muscle cell development GO:0055001 115 0.010
embryonic skeletal joint morphogenesis GO:0060272 3 0.010
rna biosynthetic process GO:0032774 181 0.010
neural crest cell migration GO:0001755 42 0.010
morphogenesis of an epithelial sheet GO:0002011 49 0.010
regulation of metabolic process GO:0019222 359 0.010
regulation of neurogenesis GO:0050767 87 0.010
positive regulation of cytoskeleton organization GO:0051495 3 0.010
Human Mouse
proteolysis GO:0006508 38 0.010
muscle tissue development GO:0060537 110 0.010

evla disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of cellular proliferation DOID:14566 0 0.022
cancer DOID:162 0 0.022
organ system cancer DOID:0050686 0 0.021
disease of anatomical entity DOID:7 0 0.012
musculoskeletal system disease DOID:17 0 0.012
disease of metabolism DOID:0014667 0 0.011