Danio rerio

0 known processes

evpl

envoplakin

(Aliases: wu:fb17b09)

evpl biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
death GO:0016265 121 0.492
keratinocyte differentiation GO:0030216 0 0.354
regulation of biological quality GO:0065008 263 0.332
central nervous system development GO:0007417 387 0.328
developmental growth GO:0048589 166 0.325
digestive tract development GO:0048565 265 0.317
regulation of multicellular organismal process GO:0051239 277 0.285
response to stress GO:0006950 263 0.226
skin development GO:0043588 54 0.218
regulation of primary metabolic process GO:0080090 311 0.209
signal transduction GO:0007165 455 0.203
regulation of apoptotic process GO:0042981 98 0.194
nitrogen compound metabolic process GO:0006807 319 0.175
regionalization GO:0003002 274 0.169
cellular response to lipid GO:0071396 39 0.168
response to abiotic stimulus GO:0009628 122 0.167
hematopoietic or lymphoid organ development GO:0048534 191 0.167
system process GO:0003008 185 0.166
protein secretion GO:0009306 1 0.160
homeostatic process GO:0042592 142 0.143
positive regulation of cellular component biogenesis GO:0044089 3 0.139
response to steroid hormone GO:0048545 35 0.137
water homeostasis GO:0030104 4 0.136
behavior GO:0007610 74 0.136
positive regulation of cell death GO:0010942 29 0.134
regulation of establishment of protein localization GO:0070201 4 0.128
nucleobase containing compound metabolic process GO:0006139 274 0.126
regulation of nitrogen compound metabolic process GO:0051171 251 0.123
epidermal cell differentiation GO:0009913 36 0.118
positive regulation of apoptotic process GO:0043065 29 0.117
chordate embryonic development GO:0043009 271 0.114
stem cell development GO:0048864 82 0.110
hemopoiesis GO:0030097 183 0.109
carboxylic acid metabolic process GO:0019752 22 0.105
regeneration GO:0031099 91 0.097
brain development GO:0007420 293 0.096
response to wounding GO:0009611 116 0.096
positive regulation of apoptotic signaling pathway GO:2001235 1 0.095
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.094
positive regulation of transport GO:0051050 2 0.094
oxoacid metabolic process GO:0043436 31 0.094
hormone secretion GO:0046879 2 0.092
cell death GO:0008219 121 0.090
digestive system development GO:0055123 289 0.090
small molecule metabolic process GO:0044281 77 0.088
programmed cell death GO:0012501 119 0.088
heterocycle metabolic process GO:0046483 290 0.086
apoptotic process GO:0006915 116 0.085
embryonic organ development GO:0048568 381 0.084
negative regulation of protein transport GO:0051224 3 0.083
extrinsic apoptotic signaling pathway GO:0097191 3 0.081
neural crest cell development GO:0014032 62 0.079
positive regulation of biological process GO:0048518 253 0.079
digestive tract morphogenesis GO:0048546 231 0.077
head development GO:0060322 303 0.076
growth GO:0040007 174 0.075
cellular response to external stimulus GO:0071496 2 0.074
central nervous system myelin formation GO:0032289 1 0.071
tissue remodeling GO:0048771 4 0.070
response to organic substance GO:0010033 153 0.070
tube morphogenesis GO:0035239 349 0.069
morphogenesis of an epithelium GO:0002009 333 0.069
aging GO:0007568 2 0.069
immune system development GO:0002520 191 0.069
eye development GO:0001654 277 0.068
positive regulation of cell cycle GO:0045787 3 0.067
mesenchyme development GO:0060485 127 0.066
response to lipid GO:0033993 60 0.066
negative regulation of secretion GO:0051048 2 0.065
peptide transport GO:0015833 1 0.064
regulation of programmed cell death GO:0043067 101 0.063
cellular macromolecule metabolic process GO:0044260 391 0.062
embryonic organ morphogenesis GO:0048562 274 0.060
positive regulation of cellular process GO:0048522 201 0.060
cellular aromatic compound metabolic process GO:0006725 295 0.060
organelle fusion GO:0048284 3 0.060
neural crest cell differentiation GO:0014033 72 0.059
regulation of cell proliferation GO:0042127 37 0.058
embryo development ending in birth or egg hatching GO:0009792 271 0.058
protein complex subunit organization GO:0071822 46 0.058
organic cyclic compound metabolic process GO:1901360 301 0.056
cellular response to organic cyclic compound GO:0071407 38 0.056
myofibril assembly GO:0030239 48 0.055
cellular biosynthetic process GO:0044249 286 0.055
wound healing GO:0042060 90 0.053
regulation of localization GO:0032879 104 0.050
negative regulation of epithelial cell proliferation GO:0050680 1 0.049
regulation of epithelial cell proliferation GO:0050678 3 0.049
gastrulation GO:0007369 208 0.048
regulation of heart contraction GO:0008016 32 0.048
hormone transport GO:0009914 2 0.048
cellular response to chemical stimulus GO:0070887 157 0.048
response to corticosteroid GO:0031960 1 0.047
cellular nitrogen compound metabolic process GO:0034641 290 0.047
meiotic nuclear division GO:0007126 4 0.047
nucleic acid metabolic process GO:0090304 244 0.047
regulation of cardiac muscle contraction GO:0055117 2 0.047
sensory organ development GO:0007423 393 0.047
fin regeneration GO:0031101 51 0.047
organic acid catabolic process GO:0016054 3 0.046
immune system process GO:0002376 241 0.046
lipid digestion GO:0044241 3 0.046
response to oxygen containing compound GO:1901700 55 0.045
epidermis development GO:0008544 48 0.045
positive regulation of extrinsic apoptotic signaling pathway GO:2001238 1 0.044
plasma membrane repair GO:0001778 2 0.043
connective tissue development GO:0061448 99 0.043
tissue regeneration GO:0042246 74 0.043
liver development GO:0001889 96 0.043
neuron differentiation GO:0030182 353 0.043
organic acid metabolic process GO:0006082 31 0.042
regulation of cell death GO:0010941 103 0.041
camera type eye morphogenesis GO:0048593 108 0.041
cellular response to starvation GO:0009267 1 0.041
phagocytosis GO:0006909 3 0.040
cell surface receptor signaling pathway GO:0007166 325 0.040
long chain fatty acid transport GO:0015909 1 0.040
single organism transport GO:0044765 206 0.040
neuron projection development GO:0031175 180 0.040
hair cell differentiation GO:0035315 32 0.040
membrane fusion GO:0061025 2 0.040
regulation of biosynthetic process GO:0009889 250 0.039
biosynthetic process GO:0009058 294 0.038
negative regulation of blood vessel endothelial cell migration GO:0043537 1 0.038
action potential GO:0001508 19 0.038
circulatory system process GO:0003013 87 0.038
myelin assembly GO:0032288 1 0.038
epithelial tube morphogenesis GO:0060562 148 0.037
epithelial cell differentiation GO:0030855 116 0.037
positive regulation of programmed cell death GO:0043068 29 0.037
regulation of protein transport GO:0051223 3 0.036
regulation of gene expression GO:0010468 265 0.036
embryonic skeletal system development GO:0048706 97 0.036
single organism membrane fusion GO:0044801 2 0.036
regulation of cellular biosynthetic process GO:0031326 245 0.036
cartilage development GO:0051216 96 0.035
protein modification process GO:0036211 100 0.035
sympathetic nervous system development GO:0048485 3 0.035
regulation of cardiac muscle cell contraction GO:0086004 1 0.035
digestive system process GO:0022600 9 0.034
negative regulation of multicellular organismal process GO:0051241 69 0.034
response to organic cyclic compound GO:0014070 51 0.034
regulation of rna metabolic process GO:0051252 224 0.033
homeostasis of number of cells GO:0048872 62 0.033
cellular response to steroid hormone stimulus GO:0071383 31 0.032
fin morphogenesis GO:0033334 53 0.032
phagocytosis engulfment GO:0006911 1 0.031
reactive oxygen species biosynthetic process GO:1903409 1 0.031
leukocyte homeostasis GO:0001776 2 0.031
regulation of developmental process GO:0050793 247 0.031
actin mediated cell contraction GO:0070252 1 0.031
ribonucleoside monophosphate catabolic process GO:0009158 4 0.031
response to external stimulus GO:0009605 264 0.030
lateral line system development GO:0048925 76 0.030
ventricular cardiac muscle tissue morphogenesis GO:0055010 2 0.030
locomotion GO:0040011 313 0.030
alpha amino acid metabolic process GO:1901605 3 0.030
ameboidal type cell migration GO:0001667 143 0.030
cell motility GO:0048870 244 0.030
multi organism process GO:0051704 134 0.029
response to inorganic substance GO:0010035 38 0.029
desmosome assembly GO:0002159 2 0.029
urogenital system development GO:0001655 97 0.029
response to endogenous stimulus GO:0009719 83 0.029
hepaticobiliary system development GO:0061008 98 0.028
cell morphogenesis GO:0000902 289 0.028
response to hormone GO:0009725 48 0.028
regulation of heart rate GO:0002027 5 0.028
cell cell signaling GO:0007267 52 0.027
regulation of striated muscle contraction GO:0006942 2 0.027
negative regulation of biological process GO:0048519 304 0.027
retina development in camera type eye GO:0060041 146 0.027
inner ear morphogenesis GO:0042472 63 0.026
morphogenesis of an epithelial sheet GO:0002011 49 0.026
hindbrain development GO:0030902 91 0.026
response to glucocorticoid GO:0051384 1 0.026
heart process GO:0003015 71 0.026
embryonic appendage morphogenesis GO:0035113 30 0.026
mesenchymal cell differentiation GO:0048762 87 0.025
cellular localization GO:0051641 97 0.025
transport GO:0006810 220 0.025
cranial nerve development GO:0021545 42 0.025
cellular response to extracellular stimulus GO:0031668 2 0.025
response to estrogen GO:0043627 27 0.025
regulation of multicellular organismal development GO:2000026 223 0.025
response to radiation GO:0009314 51 0.025
localization of cell GO:0051674 244 0.025
regulation of macromolecule metabolic process GO:0060255 317 0.024
cellular component movement GO:0006928 335 0.024
regulation of membrane potential GO:0042391 23 0.024
regulation of water loss via skin GO:0033561 1 0.024
developmental growth involved in morphogenesis GO:0060560 86 0.024
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.024
organonitrogen compound metabolic process GO:1901564 74 0.023
autophagy GO:0006914 4 0.023
multicellular organism growth GO:0035264 4 0.023
nerve development GO:0021675 45 0.023
mesenchymal cell development GO:0014031 78 0.023
heart contraction GO:0060047 71 0.023
regulation of cellular ketone metabolic process GO:0010565 7 0.022
heart morphogenesis GO:0003007 156 0.022
cell projection organization GO:0030030 284 0.022
pancreas development GO:0031016 84 0.022
lipid storage GO:0019915 1 0.022
negative regulation of secretion by cell GO:1903531 2 0.021
pigment cell differentiation GO:0050931 38 0.021
sensory organ morphogenesis GO:0090596 200 0.021
muscle cell differentiation GO:0042692 139 0.021
regulation of epidermis development GO:0045682 2 0.021
positive regulation of macromolecule metabolic process GO:0010604 93 0.021
regulation of metabolic process GO:0019222 359 0.021
regulation of organ growth GO:0046620 3 0.021
medial fin development GO:0033338 16 0.021
carboxylic acid catabolic process GO:0046395 3 0.020
regulation of growth rate GO:0040009 1 0.020
regulation of multicellular organism growth GO:0040014 4 0.020
regulation of actin filament based movement GO:1903115 1 0.020
regulation of cytokine production GO:0001817 3 0.020
heterocycle biosynthetic process GO:0018130 215 0.020
gland development GO:0048732 143 0.020
adherens junction organization GO:0034332 4 0.020
protein polymerization GO:0051258 4 0.020
response to drug GO:0042493 3 0.020
regulation of purine nucleotide catabolic process GO:0033121 2 0.020
pigmentation GO:0043473 85 0.020
negative regulation of metabolic process GO:0009892 86 0.020
neuronal action potential GO:0019228 18 0.019
intestinal absorption GO:0050892 2 0.019
cell proliferation GO:0008283 80 0.019
muscle structure development GO:0061061 196 0.019
positive regulation of secretion GO:0051047 1 0.019
intestinal cholesterol absorption GO:0030299 2 0.019
regulation of muscle contraction GO:0006937 3 0.019
gene expression GO:0010467 252 0.018
cellular nitrogen compound biosynthetic process GO:0044271 218 0.018
establishment of localization GO:0051234 244 0.018
striated muscle cell differentiation GO:0051146 129 0.018
t cell activation GO:0042110 6 0.018
positive regulation of cellular metabolic process GO:0031325 94 0.018
blood circulation GO:0008015 87 0.018
myeloid cell homeostasis GO:0002262 56 0.018
regulation of cell migration involved in sprouting angiogenesis GO:0090049 3 0.018
organism emergence from protective structure GO:0071684 4 0.018
purine ribonucleoside monophosphate catabolic process GO:0009169 4 0.018
organic substance transport GO:0071702 58 0.018
organic substance biosynthetic process GO:1901576 289 0.017
response to topologically incorrect protein GO:0035966 2 0.017
ear morphogenesis GO:0042471 64 0.017
response to other organism GO:0051707 97 0.017
skeletal system development GO:0001501 181 0.017
regulation of eye photoreceptor cell development GO:0042478 2 0.017
macromolecule modification GO:0043412 111 0.017
regulation of protein complex assembly GO:0043254 3 0.017
cellular response to endogenous stimulus GO:0071495 68 0.016
cellular response to nutrient levels GO:0031669 2 0.016
cellular component morphogenesis GO:0032989 336 0.016
cell cycle g1 s phase transition GO:0044843 1 0.016
response to nutrient GO:0007584 3 0.016
convergent extension involved in gastrulation GO:0060027 71 0.016
negative regulation of macromolecule metabolic process GO:0010605 76 0.016
adult behavior GO:0030534 2 0.016
cartilage condensation GO:0001502 3 0.016
protein metabolic process GO:0019538 183 0.016
positive regulation of metabolic process GO:0009893 108 0.016
synaptic transmission GO:0007268 35 0.015
actin filament based process GO:0030029 64 0.015
erythrocyte homeostasis GO:0034101 55 0.015
membrane invagination GO:0010324 1 0.015
female sex differentiation GO:0046660 4 0.015
ventricular cardiac muscle tissue development GO:0003229 3 0.015
cardiac muscle cell contraction GO:0086003 1 0.015
neural crest cell migration GO:0001755 42 0.015
inner ear receptor cell development GO:0060119 20 0.015
catabolic process GO:0009056 32 0.015
neural tube development GO:0021915 62 0.015
negative regulation of catabolic process GO:0009895 3 0.015
specification of symmetry GO:0009799 204 0.015
multicellular organismal homeostasis GO:0048871 29 0.015
positive regulation of nucleoside metabolic process GO:0045979 1 0.015
wnt signaling pathway GO:0016055 80 0.014
skeletal system morphogenesis GO:0048705 102 0.014
cellular response to organic substance GO:0071310 105 0.014
negative regulation of cytokine production GO:0001818 1 0.014
regulation of rna biosynthetic process GO:2001141 213 0.014
positive regulation of purine nucleotide catabolic process GO:0033123 1 0.014
anterior posterior pattern specification GO:0009952 152 0.014
nucleoside monophosphate catabolic process GO:0009125 4 0.014
actin filament based movement GO:0030048 1 0.014
regulation of cell activation GO:0050865 1 0.014
cellular ketone metabolic process GO:0042180 11 0.014
negative regulation of kinase activity GO:0033673 4 0.014
regulation of hormone levels GO:0010817 21 0.014
regulation of metal ion transport GO:0010959 4 0.013
atp catabolic process GO:0006200 4 0.013
chemical homeostasis GO:0048878 49 0.013
regulation of binding GO:0051098 3 0.013
developmental pigmentation GO:0048066 48 0.013
morphogenesis of an epithelial fold GO:0060571 1 0.013
vasculature development GO:0001944 278 0.013
small molecule catabolic process GO:0044282 3 0.013
neuroblast differentiation GO:0014016 1 0.013
organelle assembly GO:0070925 110 0.013
negative regulation of cellular process GO:0048523 283 0.013
regulation of catalytic activity GO:0050790 55 0.013
polarized epithelial cell differentiation GO:0030859 4 0.013
post anal tail morphogenesis GO:0036342 19 0.013
regulation of molecular function GO:0065009 70 0.013
response to alcohol GO:0097305 14 0.013
axial mesoderm development GO:0048318 10 0.013
ensheathment of neurons GO:0007272 18 0.013
regulation of response to stimulus GO:0048583 269 0.013
ectodermal cell fate specification GO:0001715 2 0.012
neuron development GO:0048666 262 0.012
regulation of transport GO:0051049 45 0.012
appendage development GO:0048736 80 0.012
regulation of epithelial to mesenchymal transition GO:0010717 3 0.012
gtp metabolic process GO:0046039 4 0.012
regulation of protein ubiquitination GO:0031396 3 0.012
response to chemical GO:0042221 320 0.012
hatching GO:0035188 4 0.012
establishment of skin barrier GO:0061436 1 0.012
single organism localization GO:1902578 225 0.012
establishment of localization in cell GO:0051649 77 0.012
segmentation GO:0035282 97 0.012
regulation of cellular metabolic process GO:0031323 320 0.012
stem cell maintenance GO:0019827 4 0.012
epiboly GO:0090504 41 0.012
regulation of locomotion GO:0040012 55 0.012
cell part morphogenesis GO:0032990 246 0.012
positive regulation of lipid metabolic process GO:0045834 1 0.012
positive regulation of protein complex assembly GO:0031334 2 0.012
positive regulation of cellular biosynthetic process GO:0031328 68 0.012
positive regulation of cytoskeleton organization GO:0051495 3 0.011
nitric oxide metabolic process GO:0046209 2 0.011
auditory receptor cell differentiation GO:0042491 15 0.011
single organism metabolic process GO:0044710 217 0.011
response to hydrogen peroxide GO:0042542 3 0.011
regulation of transcription from rna polymerase ii promoter GO:0006357 114 0.011
organic acid biosynthetic process GO:0016053 12 0.011
regulation of cytoplasmic transport GO:1903649 4 0.011
regulation of protein modification by small protein conjugation or removal GO:1903320 3 0.011
epiboly involved in gastrulation with mouth forming second GO:0055113 35 0.011
organelle organization GO:0006996 227 0.011
cellular protein metabolic process GO:0044267 129 0.011
multicellular organismal signaling GO:0035637 22 0.011
positive regulation of catabolic process GO:0009896 4 0.011
phosphate containing compound metabolic process GO:0006796 108 0.011
ear development GO:0043583 127 0.011
regulation of macromolecule biosynthetic process GO:0010556 225 0.010
regulation of growth GO:0040008 42 0.010
endoderm formation GO:0001706 29 0.010
regulation of embryonic development GO:0045995 47 0.010
angiogenesis GO:0001525 158 0.010
cellular response to oxygen levels GO:0071453 1 0.010
blood vessel development GO:0001568 246 0.010
endoplasmic reticulum unfolded protein response GO:0030968 2 0.010
cognition GO:0050890 1 0.010
cell aggregation GO:0098743 3 0.010
apoptotic signaling pathway GO:0097190 23 0.010
nucleotide metabolic process GO:0009117 28 0.010

evpl disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
myopathy DOID:423 0 0.077
muscular disease DOID:0080000 0 0.077
heart disease DOID:114 0 0.077
cardiomyopathy DOID:0050700 0 0.077
disease of anatomical entity DOID:7 0 0.077
cardiovascular system disease DOID:1287 0 0.077
musculoskeletal system disease DOID:17 0 0.077
muscle tissue disease DOID:66 0 0.077
keratosis DOID:161 0 0.015
skin disease DOID:37 0 0.015
integumentary system disease DOID:16 0 0.015