Danio rerio

33 known processes

ewsr1a

Ewing sarcoma breakpoint region 1a

(Aliases: fc04c01,EWSR1,wu:fc04c01)

ewsr1a biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
single organism organelle organization GO:1902589 199 0.473
negative regulation of ras protein signal transduction GO:0046580 1 0.461
spliceosomal complex assembly GO:0000245 1 0.364
regulation of gene expression GO:0010468 265 0.328
regulation of macromolecule metabolic process GO:0060255 317 0.327
organelle assembly GO:0070925 110 0.294
cellular component assembly GO:0022607 170 0.280
Fly
nucleic acid metabolic process GO:0090304 244 0.245
nitrogen compound metabolic process GO:0006807 319 0.226
regionalization GO:0003002 274 0.218
cellular component biogenesis GO:0044085 178 0.211
Fly
gene expression GO:0010467 252 0.205
cellular nitrogen compound metabolic process GO:0034641 290 0.197
dorsal ventral pattern formation GO:0009953 125 0.154
positive regulation of biological process GO:0048518 253 0.153
Fly
regulation of synapse organization GO:0050807 3 0.139
Fly
larval development GO:0002164 2 0.132
adult behavior GO:0030534 2 0.131
Fly
negative regulation of cellular process GO:0048523 283 0.125
mrna processing GO:0006397 14 0.124
embryo development ending in birth or egg hatching GO:0009792 271 0.124
regulation of calcium ion dependent exocytosis GO:0017158 1 0.120
regulation of synapse assembly GO:0051963 3 0.118
Fly
cellular macromolecule metabolic process GO:0044260 391 0.117
negative regulation of small gtpase mediated signal transduction GO:0051058 1 0.108
regulation of rna metabolic process GO:0051252 224 0.108
negative regulation of signaling GO:0023057 96 0.107
organic substance biosynthetic process GO:1901576 289 0.101
heterocycle metabolic process GO:0046483 290 0.098
regulation of multicellular organismal development GO:2000026 223 0.095
Fly
cellular aromatic compound metabolic process GO:0006725 295 0.093
regulation of primary metabolic process GO:0080090 311 0.093
positive regulation of transport GO:0051050 2 0.092
regulation of nitrogen compound metabolic process GO:0051171 251 0.086
viral process GO:0016032 1 0.084
multi organism cellular process GO:0044764 2 0.080
regulation of mrna stability GO:0043488 4 0.078
nucleic acid templated transcription GO:0097659 181 0.076
regulation of metabolic process GO:0019222 359 0.076
meiotic nuclear division GO:0007126 4 0.075
rna splicing GO:0008380 16 0.072
mrna splicing via spliceosome GO:0000398 10 0.071
rna stabilization GO:0043489 4 0.071
transcription dna templated GO:0006351 181 0.070
organic cyclic compound metabolic process GO:1901360 301 0.070
ribonucleoprotein complex biogenesis GO:0022613 13 0.068
locomotion GO:0040011 313 0.067
organelle organization GO:0006996 227 0.066
regulation of cellular metabolic process GO:0031323 320 0.065
cell projection organization GO:0030030 284 0.063
negative regulation of rna splicing GO:0033119 1 0.062
aromatic compound biosynthetic process GO:0019438 217 0.061
positive regulation of extrinsic apoptotic signaling pathway GO:2001238 1 0.060
protein metabolic process GO:0019538 183 0.059
regulation of signal transduction GO:0009966 225 0.059
cilium morphogenesis GO:0060271 85 0.058
negative regulation of synapse assembly GO:0051964 2 0.058
larval behavior GO:0030537 5 0.057
Fly
chordate embryonic development GO:0043009 271 0.055
compound eye development GO:0048749 2 0.054
Fly
negative regulation of signal transduction GO:0009968 94 0.054
rna splicing via transesterification reactions with bulged adenosine as nucleophile GO:0000377 10 0.054
negative regulation of gene expression GO:0010629 65 0.054
convergent extension GO:0060026 118 0.052
somite development GO:0061053 96 0.052
cellular component movement GO:0006928 335 0.050
regulation of mrna processing GO:0050684 3 0.049
regulation of multicellular organismal process GO:0051239 277 0.049
Fly
multi organism process GO:0051704 134 0.049
positive regulation of nucleic acid templated transcription GO:1903508 57 0.049
pole plasm assembly GO:0007315 4 0.048
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.048
Fly
regulation of signaling GO:0023051 235 0.048
muscle cell differentiation GO:0042692 139 0.047
regulation of reproductive process GO:2000241 4 0.047
cellular nitrogen compound biosynthetic process GO:0044271 218 0.046
ribonucleoprotein complex assembly GO:0022618 5 0.045
cellular biosynthetic process GO:0044249 286 0.045
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.044
regulation of macromolecule biosynthetic process GO:0010556 225 0.044
aging GO:0007568 2 0.044
microtubule based process GO:0007017 60 0.044
positive regulation of rna metabolic process GO:0051254 59 0.043
protein acylation GO:0043543 3 0.043
regulation of dna templated transcription elongation GO:0032784 3 0.043
positive regulation of exocytosis GO:0045921 1 0.042
immune system process GO:0002376 241 0.042
larval locomotory behavior GO:0008345 5 0.041
Fly
positive regulation of nucleobase containing compound metabolic process GO:0045935 69 0.041
regulation of developmental process GO:0050793 247 0.041
Fly
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.040
3 utr mediated mrna stabilization GO:0070935 3 0.040
heterocycle biosynthetic process GO:0018130 215 0.039
regulation of neural precursor cell proliferation GO:2000177 3 0.039
rna biosynthetic process GO:0032774 181 0.039
regulation of cell activation GO:0050865 1 0.038
regulation of cellular component organization GO:0051128 86 0.038
Fly
fertilization GO:0009566 3 0.037
regulation of biological quality GO:0065008 263 0.037
Fly
transcription from rna polymerase ii promoter GO:0006366 80 0.037
mrna metabolic process GO:0016071 20 0.036
stem cell differentiation GO:0048863 117 0.036
cellular macromolecular complex assembly GO:0034622 24 0.036
skeletal system development GO:0001501 181 0.036
stem cell maintenance GO:0019827 4 0.036
single organism localization GO:1902578 225 0.036
positive regulation of cellular biosynthetic process GO:0031328 68 0.035
positive regulation of cellular process GO:0048522 201 0.035
Fly
regulation of response to stimulus GO:0048583 269 0.034
negative regulation of cell communication GO:0010648 96 0.034
regulation of transcription from rna polymerase ii promoter GO:0006357 114 0.034
regulation of biosynthetic process GO:0009889 250 0.034
protein localization to nucleus GO:0034504 3 0.033
cytokinesis GO:0000910 3 0.033
regulation of symbiosis encompassing mutualism through parasitism GO:0043903 1 0.033
neuron differentiation GO:0030182 353 0.033
rna metabolic process GO:0016070 219 0.033
immune system development GO:0002520 191 0.033
cellular component morphogenesis GO:0032989 336 0.032
muscle structure development GO:0061061 196 0.032
regulation of establishment of protein localization GO:0070201 4 0.032
modification of morphology or physiology of other organism involved in symbiotic interaction GO:0051817 4 0.032
negative regulation of response to stimulus GO:0048585 104 0.032
macromolecular complex subunit organization GO:0043933 74 0.031
interspecies interaction between organisms GO:0044419 4 0.031
signal transduction GO:0007165 455 0.031
regulation of cytoplasmic transport GO:1903649 4 0.031
cell substrate adhesion GO:0031589 4 0.031
death GO:0016265 121 0.030
positive regulation of cellular catabolic process GO:0031331 3 0.030
cell cycle process GO:0022402 53 0.030
determination of left right symmetry GO:0007368 179 0.030
microtubule organizing center organization GO:0031023 1 0.029
biosynthetic process GO:0009058 294 0.029
multicellular organism growth GO:0035264 4 0.029
maternal determination of anterior posterior axis embryo GO:0008358 4 0.029
regulation of transcription dna templated GO:0006355 213 0.029
calcium ion dependent exocytosis GO:0017156 1 0.029
organic cyclic compound biosynthetic process GO:1901362 223 0.029
endothelial cell fate commitment GO:0060839 3 0.029
guanosine containing compound catabolic process GO:1901069 2 0.028
regulation of cell communication GO:0010646 232 0.028
determination of bilateral symmetry GO:0009855 204 0.028
positive regulation of metabolic process GO:0009893 108 0.028
modification of morphology or physiology of other organism GO:0035821 4 0.028
positive regulation of cellular component biogenesis GO:0044089 3 0.028
Fly
positive regulation of calcium ion dependent exocytosis GO:0045956 1 0.028
neuroblast proliferation GO:0007405 2 0.027
regulation of intracellular protein transport GO:0033157 3 0.027
positive regulation of reproductive process GO:2000243 2 0.027
rna processing GO:0006396 25 0.027
anterior posterior pattern specification GO:0009952 152 0.027
synaptic growth at neuromuscular junction GO:0051124 2 0.027
Fly
muscle tissue development GO:0060537 110 0.026
cartilage development GO:0051216 96 0.026
positive regulation of cellular metabolic process GO:0031325 94 0.026
hemopoiesis GO:0030097 183 0.026
digestive system development GO:0055123 289 0.026
regulation of dendrite morphogenesis GO:0048814 3 0.026
growth GO:0040007 174 0.025
Fly
b cell activation GO:0042113 2 0.025
regulation of rna biosynthetic process GO:2001141 213 0.025
regulation of growth GO:0040008 42 0.024
Fly
stem cell proliferation GO:0072089 4 0.024
macromolecule biosynthetic process GO:0009059 227 0.024
nucleobase containing compound metabolic process GO:0006139 274 0.024
cell morphogenesis GO:0000902 289 0.024
nuclear transport GO:0051169 4 0.024
positive regulation of rna biosynthetic process GO:1902680 57 0.024
negative regulation of nucleocytoplasmic transport GO:0046823 2 0.024
regulation of rac protein signal transduction GO:0035020 1 0.024
negative regulation of nitrogen compound metabolic process GO:0051172 59 0.024
developmental growth involved in morphogenesis GO:0060560 86 0.024
neuron development GO:0048666 262 0.024
positive regulation of neuron apoptotic process GO:0043525 1 0.023
cell cycle GO:0007049 93 0.023
positive regulation of cytosolic calcium ion concentration GO:0007204 4 0.023
regulation of meiotic cell cycle GO:0051445 1 0.023
cellular response to external stimulus GO:0071496 2 0.023
regulation of nucleic acid templated transcription GO:1903506 213 0.023
morphogenesis of an epithelium GO:0002009 333 0.023
lymphangiogenesis GO:0001946 25 0.023
positive regulation of biosynthetic process GO:0009891 68 0.023
hematopoietic or lymphoid organ development GO:0048534 191 0.023
cellular localization GO:0051641 97 0.023
negative regulation of wnt signaling pathway GO:0030178 30 0.022
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.022
regulation of cellular biosynthetic process GO:0031326 245 0.022
developmental growth GO:0048589 166 0.022
Fly
multi organism reproductive process GO:0044703 36 0.022
localization of cell GO:0051674 244 0.022
angiogenesis GO:0001525 158 0.021
regulation of protein targeting GO:1903533 2 0.021
mesenchymal cell proliferation GO:0010463 1 0.021
positive regulation of myeloid cell differentiation GO:0045639 2 0.021
nuclear import GO:0051170 3 0.021
cellular macromolecule biosynthetic process GO:0034645 224 0.021
regulation of nucleocytoplasmic transport GO:0046822 2 0.021
positive regulation of cellular carbohydrate metabolic process GO:0010676 1 0.021
histone h3 k4 methylation GO:0051568 2 0.020
mesenchymal cell differentiation GO:0048762 87 0.020
central nervous system development GO:0007417 387 0.020
nuclear division GO:0000280 23 0.020
negative regulation of biosynthetic process GO:0009890 55 0.020
dorsal ventral axis specification GO:0009950 14 0.019
mrna stabilization GO:0048255 4 0.019
tube morphogenesis GO:0035239 349 0.019
exocytosis GO:0006887 1 0.019
protein import into nucleus GO:0006606 3 0.019
establishment of protein localization to organelle GO:0072594 4 0.019
positive regulation of catabolic process GO:0009896 4 0.019
regulation of dendrite development GO:0050773 3 0.019
negative regulation of macromolecule metabolic process GO:0010605 76 0.018
regulation of organelle assembly GO:1902115 4 0.018
neural crest cell differentiation GO:0014033 72 0.018
gene silencing by mirna GO:0035195 3 0.018
myeloid cell differentiation GO:0030099 86 0.018
negative regulation of histone modification GO:0031057 1 0.018
regulation of gene expression epigenetic GO:0040029 11 0.018
protein complex localization GO:0031503 1 0.018
segmentation GO:0035282 97 0.018
nucleocytoplasmic transport GO:0006913 4 0.018
specification of symmetry GO:0009799 204 0.018
cell surface receptor signaling pathway GO:0007166 325 0.017
stem cell development GO:0048864 82 0.017
regulation of protein import into nucleus GO:0042306 2 0.017
embryonic organ morphogenesis GO:0048562 274 0.017
establishment of localization GO:0051234 244 0.017
positive regulation of synapse assembly GO:0051965 1 0.017
Fly
somitogenesis GO:0001756 87 0.017
cytoplasm organization GO:0007028 4 0.017
phagocytosis GO:0006909 3 0.017
positive regulation of cell activation GO:0050867 1 0.017
protein complex subunit organization GO:0071822 46 0.017
amine metabolic process GO:0009308 2 0.017
gtp metabolic process GO:0046039 4 0.017
cell part morphogenesis GO:0032990 246 0.016
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.016
single fertilization GO:0007338 3 0.016
peptidyl lysine acetylation GO:0018394 2 0.016
cell matrix adhesion GO:0007160 4 0.016
liver development GO:0001889 96 0.016
nerve development GO:0021675 45 0.016
carboxylic acid metabolic process GO:0019752 22 0.016
positive regulation of mrna metabolic process GO:1903313 2 0.016
protein targeting to nucleus GO:0044744 3 0.016
behavior GO:0007610 74 0.016
Fly
regulation of dna templated transcription in response to stress GO:0043620 0 0.015
cellular response to extracellular stimulus GO:0031668 2 0.015
centrosome cycle GO:0007098 1 0.015
positive regulation of mesenchymal cell proliferation GO:0002053 1 0.015
single organism transport GO:0044765 206 0.015
somatic cell dna recombination GO:0016444 1 0.015
nucleobase containing compound biosynthetic process GO:0034654 205 0.015
oocyte anterior posterior axis specification GO:0007314 4 0.015
negative regulation of metabolic process GO:0009892 86 0.015
protein acetylation GO:0006473 2 0.015
spindle assembly GO:0051225 2 0.015
programmed cell death GO:0012501 119 0.015
symbiosis encompassing mutualism through parasitism GO:0044403 4 0.015
actin polymerization or depolymerization GO:0008154 2 0.014
regulation of developmental growth GO:0048638 38 0.014
Fly
cell morphogenesis involved in differentiation GO:0000904 195 0.014
somatic muscle development GO:0007525 4 0.014
negative regulation of multicellular organismal process GO:0051241 69 0.014
positive regulation of neuron death GO:1901216 1 0.014
developmental pigmentation GO:0048066 48 0.014
taxis GO:0042330 109 0.014
cell migration GO:0016477 237 0.014
regulation of multicellular organism growth GO:0040014 4 0.014
axis specification GO:0009798 43 0.014
regulation of cell maturation GO:1903429 1 0.014
negative regulation of intracellular transport GO:0032387 3 0.014
positive regulation of macromolecule biosynthetic process GO:0010557 59 0.014
striated muscle cell development GO:0055002 108 0.014
internal peptidyl lysine acetylation GO:0018393 2 0.014
negative regulation of multi organism process GO:0043901 3 0.014
mitotic nuclear division GO:0007067 18 0.014
regulation of protein transport GO:0051223 3 0.014
cell death GO:0008219 121 0.014
transport GO:0006810 220 0.013
regulation of gtpase activity GO:0043087 2 0.013
pigment cell differentiation GO:0050931 38 0.013
rna localization GO:0006403 4 0.013
protein secretion GO:0009306 1 0.013
regulation of cell death GO:0010941 103 0.013
gtp catabolic process GO:0006184 2 0.013
regulation of protein binding GO:0043393 3 0.013
positive regulation of transcription dna templated GO:0045893 57 0.013
protein polymerization GO:0051258 4 0.013
keratinocyte differentiation GO:0030216 0 0.013
mesenchyme development GO:0060485 127 0.013
muscle cell development GO:0055001 115 0.013
response to uv GO:0009411 3 0.012
spermatid differentiation GO:0048515 2 0.012
development of primary sexual characteristics GO:0045137 5 0.012
hepaticobiliary system development GO:0061008 98 0.012
apoptotic process GO:0006915 116 0.012
meiotic cell cycle process GO:1903046 3 0.012
ras protein signal transduction GO:0007265 7 0.012
negative regulation of i kappab kinase nf kappab signaling GO:0043124 1 0.012
regulation of lipid transport GO:0032368 4 0.012
positive regulation of cellular amine metabolic process GO:0033240 0 0.012
cellular homeostasis GO:0019725 26 0.012
positive regulation of apoptotic signaling pathway GO:2001235 1 0.012
oocyte development GO:0048599 14 0.012
cell maturation GO:0048469 23 0.012
protein import GO:0017038 3 0.012
regulation of nervous system development GO:0051960 90 0.012
Fly
reproductive process GO:0022414 40 0.012
convergent extension involved in gastrulation GO:0060027 71 0.012
regulation of mrna splicing via spliceosome GO:0048024 3 0.012
regulation of oligodendrocyte differentiation GO:0048713 1 0.012
regulation of organelle organization GO:0033043 29 0.012
negative regulation of cytoplasmic transport GO:1903650 2 0.012
negative regulation of nucleobase containing compound metabolic process GO:0045934 59 0.011
melanocyte differentiation GO:0030318 26 0.011
neuron projection guidance GO:0097485 86 0.011
posttranscriptional gene silencing by rna GO:0035194 3 0.011
epithelial cell differentiation GO:0030855 116 0.011
histone deacetylation GO:0016575 2 0.011
regulation of rna stability GO:0043487 5 0.011
negative regulation of leukocyte differentiation GO:1902106 1 0.011
regulation of growth rate GO:0040009 1 0.011
determination of heart left right asymmetry GO:0061371 117 0.011
small gtpase mediated signal transduction GO:0007264 8 0.011
cellular protein catabolic process GO:0044257 4 0.011
regulation of binding GO:0051098 3 0.011
homeostatic process GO:0042592 142 0.011
developmental maturation GO:0021700 34 0.011
nuclear export GO:0051168 1 0.011
response to external stimulus GO:0009605 264 0.011
meiotic spindle organization GO:0000212 1 0.011
regulation of purine nucleotide catabolic process GO:0033121 2 0.011
regulation of gtp catabolic process GO:0033124 2 0.011
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.011
organism emergence from protective structure GO:0071684 4 0.011
protein depolymerization GO:0051261 1 0.011
response to amino acid GO:0043200 2 0.011
regulation of nucleoside metabolic process GO:0009118 2 0.011
cilium assembly GO:0042384 58 0.011
blood vessel development GO:0001568 246 0.011
negative regulation of reproductive process GO:2000242 3 0.011
columnar cuboidal epithelial cell differentiation GO:0002065 38 0.011
regulation of cell proliferation involved in heart morphogenesis GO:2000136 2 0.011
regulation of cellular response to oxidative stress GO:1900407 2 0.011
cellular component assembly involved in morphogenesis GO:0010927 107 0.011
maintenance of location GO:0051235 4 0.011
leukocyte proliferation GO:0070661 1 0.011
intracellular mrna localization GO:0008298 1 0.010
neuromuscular synaptic transmission GO:0007274 2 0.010
negative regulation of chromosome organization GO:2001251 1 0.010
positive regulation of notch signaling pathway GO:0045747 3 0.010
central nervous system neuron development GO:0021954 29 0.010
erythrocyte maturation GO:0043249 8 0.010
multicellular organismal metabolic process GO:0044236 2 0.010
cell death in response to oxidative stress GO:0036473 2 0.010
cell proliferation GO:0008283 80 0.010
exocrine pancreas development GO:0031017 28 0.010
positive regulation of chromosome segregation GO:0051984 1 0.010
embryonic organ development GO:0048568 381 0.010
small molecule metabolic process GO:0044281 77 0.010
cellular protein metabolic process GO:0044267 129 0.010
cortical granule exocytosis GO:0060471 1 0.010

ewsr1a disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.101
motor neuron disease DOID:231 0 0.086
nervous system disease DOID:863 0 0.086
central nervous system disease DOID:331 0 0.086
neurodegenerative disease DOID:1289 0 0.086
amyotrophic lateral sclerosis DOID:332 0 0.086
disease of cellular proliferation DOID:14566 0 0.013
Human
cancer DOID:162 0 0.013
Human
musculoskeletal system disease DOID:17 0 0.011
muscular disease DOID:0080000 0 0.011
myopathy DOID:423 0 0.011
muscle tissue disease DOID:66 0 0.011