Danio rerio

0 known processes

ezh2

enhancer of zeste homolog 2 (Drosophila)

(Aliases: MGC136376,zgc:152758,zgc:136376,im:7149338,eya2)

ezh2 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
negative regulation of biological process GO:0048519 304 0.958
Human Mouse Worm Fly
histone h3 k36 methylation GO:0010452 2 0.729
macromolecule biosynthetic process GO:0009059 227 0.722
Human Mouse Fly
neuron development GO:0048666 262 0.593
Fly
organic substance biosynthetic process GO:1901576 289 0.574
Human Mouse Fly
cellular macromolecule metabolic process GO:0044260 391 0.568
Human Mouse Worm Fly
regulation of nitrogen compound metabolic process GO:0051171 251 0.517
Human Mouse Fly
chromatin modification GO:0016568 21 0.508
Human Mouse Worm Fly
gene expression GO:0010467 252 0.481
Human Mouse Worm Fly
methylation GO:0032259 22 0.471
Human Mouse Worm Fly
histone h4 k20 methylation GO:0034770 2 0.464
nucleobase containing compound biosynthetic process GO:0034654 205 0.444
Human Mouse Fly
regulation of gene expression GO:0010468 265 0.427
Human Mouse Worm Fly
regulation of transcription dna templated GO:0006355 213 0.408
Human Mouse Fly
cellular macromolecule biosynthetic process GO:0034645 224 0.395
Human Mouse Fly
histone lysine methylation GO:0034968 12 0.368
Human Mouse Worm Fly
regulation of rna biosynthetic process GO:2001141 213 0.361
Human Mouse Fly
negative regulation of cellular process GO:0048523 283 0.354
Human Mouse Fly
chromosome organization GO:0051276 31 0.342
Human Mouse Worm Fly
cell projection organization GO:0030030 284 0.329
Fly
regulation of circadian rhythm GO:0042752 4 0.311
Human Mouse
nitrogen compound metabolic process GO:0006807 319 0.309
Human Mouse Fly
cellular component morphogenesis GO:0032989 336 0.291
Human Fly
organic cyclic compound metabolic process GO:1901360 301 0.276
Human Mouse Fly
neuron differentiation GO:0030182 353 0.264
Fly
peptidyl lysine methylation GO:0018022 3 0.264
Fly
heterocycle metabolic process GO:0046483 290 0.259
Human Mouse Fly
regulation of cellular biosynthetic process GO:0031326 245 0.258
Human Mouse Fly
regulation of macromolecule metabolic process GO:0060255 317 0.254
Human Mouse Worm Fly
cellular nitrogen compound biosynthetic process GO:0044271 218 0.236
Human Mouse Fly
protein metabolic process GO:0019538 183 0.232
Human Mouse Worm Fly
negative regulation of metabolic process GO:0009892 86 0.230
Human Mouse Fly
regulation of cellular metabolic process GO:0031323 320 0.228
Human Mouse Fly
cellular nitrogen compound metabolic process GO:0034641 290 0.221
Human Mouse Fly
histone h3 k4 methylation GO:0051568 2 0.220
rna biosynthetic process GO:0032774 181 0.217
Human Mouse Fly
regulation of gene expression epigenetic GO:0040029 11 0.215
Human Mouse Worm
sensory organ development GO:0007423 393 0.203
protein modification process GO:0036211 100 0.202
Human Mouse Worm Fly
histone methylation GO:0016571 13 0.202
Human Mouse Worm Fly
organic cyclic compound biosynthetic process GO:1901362 223 0.201
Human Mouse Fly
biosynthetic process GO:0009058 294 0.190
Human Mouse Fly
negative regulation of nucleobase containing compound metabolic process GO:0045934 59 0.189
Human Mouse Fly
stem cell maintenance GO:0019827 4 0.186
single organism metabolic process GO:0044710 217 0.182
Human Mouse Worm Fly
histone h3 k9 methylation GO:0051567 5 0.178
Fly
negative regulation of macromolecule metabolic process GO:0010605 76 0.177
Human Mouse Fly
nucleic acid metabolic process GO:0090304 244 0.171
Human Mouse Fly
regulation of biosynthetic process GO:0009889 250 0.165
Human Mouse Fly
cellular aromatic compound metabolic process GO:0006725 295 0.164
Human Mouse Fly
negative regulation of biosynthetic process GO:0009890 55 0.164
Human Mouse Fly
response to stress GO:0006950 263 0.164
Mouse
protein methylation GO:0006479 13 0.163
Human Mouse Worm Fly
cell morphogenesis involved in differentiation GO:0000904 195 0.161
Human Fly
neuron projection development GO:0031175 180 0.160
Fly
histone modification GO:0016570 20 0.157
Human Mouse Worm Fly
protein alkylation GO:0008213 13 0.155
Human Mouse Worm Fly
regulation of metabolic process GO:0019222 359 0.152
Human Mouse Worm Fly
macromolecule modification GO:0043412 111 0.150
Human Mouse Worm Fly
muscle structure development GO:0061061 196 0.148
Mouse Fly
cellular biosynthetic process GO:0044249 286 0.147
Human Mouse Fly
generation of neurons GO:0048699 385 0.146
Mouse Fly
regulation of macromolecule biosynthetic process GO:0010556 225 0.143
Human Mouse Fly
negative regulation of gene expression GO:0010629 65 0.140
Human Mouse Fly
eye development GO:0001654 277 0.136
cellular protein modification process GO:0006464 100 0.132
Human Mouse Worm Fly
cell morphogenesis GO:0000902 289 0.130
Human Fly
nucleic acid templated transcription GO:0097659 181 0.128
Human Mouse Fly
negative regulation of cellular metabolic process GO:0031324 77 0.126
Human Mouse Fly
cellular protein metabolic process GO:0044267 129 0.126
Human Mouse Worm Fly
organelle organization GO:0006996 227 0.125
Human Mouse Worm Fly
macromolecule methylation GO:0043414 19 0.124
Human Mouse Worm Fly
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.122
Fly
negative regulation of cellular biosynthetic process GO:0031327 55 0.121
Human Mouse Fly
regulation of primary metabolic process GO:0080090 311 0.118
Human Mouse Fly
g2 m transition of mitotic cell cycle GO:0000086 4 0.113
transcription dna templated GO:0006351 181 0.109
Human Mouse Fly
heterocycle biosynthetic process GO:0018130 215 0.108
Human Mouse Fly
single organism organelle organization GO:1902589 199 0.107
Human Mouse Worm Fly
negative regulation of macromolecule biosynthetic process GO:0010558 48 0.105
Human Mouse Fly
positive regulation of cell cycle GO:0045787 3 0.104
rna metabolic process GO:0016070 219 0.103
Human Mouse Fly
mitotic dna integrity checkpoint GO:0044774 4 0.100
axon development GO:0061564 166 0.098
Fly
immune system process GO:0002376 241 0.095
neuron projection morphogenesis GO:0048812 161 0.093
Fly
digestive tract development GO:0048565 265 0.091
regulation of developmental process GO:0050793 247 0.089
Human Mouse Worm
cell part morphogenesis GO:0032990 246 0.088
Fly
negative regulation of cellular macromolecule biosynthetic process GO:2000113 48 0.088
Human Mouse Fly
axonogenesis GO:0007409 152 0.088
Fly
regulation of histone methylation GO:0031060 3 0.087
digestive system development GO:0055123 289 0.085
peptidyl lysine dimethylation GO:0018027 1 0.084
locomotion GO:0040011 313 0.084
Fly
growth GO:0040007 174 0.082
Mouse
retina development in camera type eye GO:0060041 146 0.082
covalent chromatin modification GO:0016569 20 0.077
Human Mouse Worm Fly
nucleobase containing compound metabolic process GO:0006139 274 0.077
Human Mouse Fly
histone h3 k9 modification GO:0061647 5 0.076
Fly
aromatic compound biosynthetic process GO:0019438 217 0.076
Human Mouse Fly
cell migration GO:0016477 237 0.074
production of molecular mediator of immune response GO:0002440 2 0.074
response to chemical GO:0042221 320 0.072
Mouse Fly
axon guidance GO:0007411 86 0.072
Fly
dna modification GO:0006304 8 0.070
Mouse
chromatin organization GO:0006325 22 0.070
Human Mouse Worm Fly
small molecule metabolic process GO:0044281 77 0.069
Human
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.068
Human Mouse Fly
positive regulation of lymphocyte mediated immunity GO:0002708 1 0.066
cell cycle g1 s phase transition GO:0044843 1 0.065
Mouse
gastrulation GO:0007369 208 0.064
regulation of protein catabolic process GO:0042176 1 0.063
negative regulation of nitrogen compound metabolic process GO:0051172 59 0.063
Human Mouse Fly
negative regulation of rna metabolic process GO:0051253 48 0.063
Human Mouse Fly
dna metabolic process GO:0006259 27 0.062
Mouse
larval development GO:0002164 2 0.062
Worm
energy reserve metabolic process GO:0006112 2 0.061
tube morphogenesis GO:0035239 349 0.061
regulation of chromatin organization GO:1902275 5 0.060
negative regulation of rna biosynthetic process GO:1902679 45 0.060
Human Mouse Fly
regulation of multicellular organism growth GO:0040014 4 0.060
striated muscle tissue development GO:0014706 110 0.058
positive regulation of leukocyte mediated immunity GO:0002705 1 0.057
immunoglobulin mediated immune response GO:0016064 3 0.057
peptidyl lysine trimethylation GO:0018023 1 0.056
heart development GO:0007507 313 0.056
aging GO:0007568 2 0.056
Worm
signal transduction GO:0007165 455 0.056
Human
response to radiation GO:0009314 51 0.055
regulation of nucleic acid templated transcription GO:1903506 213 0.053
Human Mouse Fly
positive regulation of macromolecule biosynthetic process GO:0010557 59 0.053
positive regulation of cellular process GO:0048522 201 0.052
Human
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.051
Human Mouse Fly
negative regulation of cell cycle GO:0045786 14 0.049
Mouse
hepaticobiliary system development GO:0061008 98 0.049
positive regulation of purine nucleotide catabolic process GO:0033123 1 0.048
Human
regulation of response to stimulus GO:0048583 269 0.047
Human
cellular component biogenesis GO:0044085 178 0.047
regulation of microtubule cytoskeleton organization GO:0070507 3 0.046
camera type eye development GO:0043010 222 0.046
cellular amine metabolic process GO:0044106 2 0.046
regulation of protein metabolic process GO:0051246 56 0.046
Human Mouse
negative regulation of nucleic acid templated transcription GO:1903507 45 0.046
Human Mouse Fly
regulation of cellular amine metabolic process GO:0033238 0 0.045
death GO:0016265 121 0.044
Worm
apoptotic process GO:0006915 116 0.044
Worm
protein acetylation GO:0006473 2 0.044
positive regulation of nucleobase containing compound metabolic process GO:0045935 69 0.044
Human
regulation of cell communication GO:0010646 232 0.043
Human
regulation of mitotic cell cycle GO:0007346 25 0.042
Mouse
cytokinesis GO:0000910 3 0.042
response to light stimulus GO:0009416 46 0.042
cell projection morphogenesis GO:0048858 244 0.041
Fly
regulation of signal transduction GO:0009966 225 0.041
Human
maintenance of location GO:0051235 4 0.041
transcription from rna polymerase ii promoter GO:0006366 80 0.040
Human Mouse
positive regulation of nucleoside metabolic process GO:0045979 1 0.040
Human
programmed cell death GO:0012501 119 0.039
Worm
regulation of multicellular organismal process GO:0051239 277 0.039
Human Mouse Worm
regulation of transcription elongation from rna polymerase ii promoter GO:0034243 3 0.038
Mouse
response to external stimulus GO:0009605 264 0.038
Fly
regulation of organelle assembly GO:1902115 4 0.038
camera type eye morphogenesis GO:0048593 108 0.038
negative regulation of transcription dna templated GO:0045892 45 0.038
Human Mouse Fly
cell death GO:0008219 121 0.038
Worm
internal protein amino acid acetylation GO:0006475 2 0.038
anterior posterior pattern specification GO:0009952 152 0.037
organonitrogen compound metabolic process GO:1901564 74 0.037
Human
negative regulation of chromosome organization GO:2001251 1 0.037
organic acid metabolic process GO:0006082 31 0.037
hemopoiesis GO:0030097 183 0.036
rna transport GO:0050658 2 0.036
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.036
Human
skeletal system development GO:0001501 181 0.036
carbohydrate biosynthetic process GO:0016051 1 0.035
neuron projection guidance GO:0097485 86 0.035
Fly
embryo development ending in birth or egg hatching GO:0009792 271 0.035
tissue regeneration GO:0042246 74 0.035
Mouse
negative regulation of dna metabolic process GO:0051053 4 0.035
central nervous system development GO:0007417 387 0.035
Mouse
dna alkylation GO:0006305 8 0.035
Mouse
immune system development GO:0002520 191 0.035
epithelial cell differentiation GO:0030855 116 0.034
Mouse
regulation of histone h3 k9 methylation GO:0051570 2 0.034
cytoskeleton organization GO:0007010 96 0.034
striated muscle cell differentiation GO:0051146 129 0.034
Mouse
negative regulation of transcription from rna polymerase ii promoter GO:0000122 16 0.033
Human Mouse
cellular component assembly involved in morphogenesis GO:0010927 107 0.033
negative regulation of kinase activity GO:0033673 4 0.033
cell cycle g2 m phase transition GO:0044839 4 0.032
regulation of extrinsic apoptotic signaling pathway GO:2001236 3 0.032
macromolecular complex subunit organization GO:0043933 74 0.032
Human Mouse Worm Fly
single fertilization GO:0007338 3 0.032
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.032
regulation of rna metabolic process GO:0051252 224 0.032
Human Mouse Fly
positive regulation of cell activation GO:0050867 1 0.031
regulation of cell death GO:0010941 103 0.031
cellular component movement GO:0006928 335 0.031
Fly
gene silencing GO:0016458 4 0.031
carboxylic acid metabolic process GO:0019752 22 0.030
ameboidal type cell migration GO:0001667 143 0.030
response to uv GO:0009411 3 0.030
rna localization GO:0006403 4 0.030
maternal determination of anterior posterior axis embryo GO:0008358 4 0.029
muscle tissue development GO:0060537 110 0.029
positive regulation of transport GO:0051050 2 0.029
peptidyl serine modification GO:0018209 2 0.028
negative regulation of cell cycle process GO:0010948 9 0.028
Mouse
protein acylation GO:0043543 3 0.028
actomyosin structure organization GO:0031032 53 0.028
head development GO:0060322 303 0.028
Mouse
positive regulation of nucleotide catabolic process GO:0030813 1 0.028
Human
amine metabolic process GO:0009308 2 0.027
internal peptidyl lysine acetylation GO:0018393 2 0.027
cellular ketone metabolic process GO:0042180 11 0.027
extrinsic apoptotic signaling pathway GO:0097191 3 0.027
regulation of protein transport GO:0051223 3 0.027
negative regulation of response to stimulus GO:0048585 104 0.027
Human
regulation of production of molecular mediator of immune response GO:0002700 1 0.026
regulation of transcription from rna polymerase ii promoter GO:0006357 114 0.026
Human Mouse
myosin filament assembly GO:0031034 6 0.026
regulation of nucleotide catabolic process GO:0030811 2 0.026
Human
cellular macromolecular complex assembly GO:0034622 24 0.026
regulation of cellular ketone metabolic process GO:0010565 7 0.026
regulation of signaling GO:0023051 235 0.026
Human
muscle cell development GO:0055001 115 0.026
regulation of apoptotic process GO:0042981 98 0.026
germ line stem cell maintenance GO:0030718 2 0.026
response to amine GO:0014075 1 0.025
small gtpase mediated signal transduction GO:0007264 8 0.025
negative regulation of nuclear division GO:0051784 3 0.025
regulation of cellular amino acid metabolic process GO:0006521 0 0.025
regulation of reproductive process GO:2000241 4 0.025
positive regulation of gtp catabolic process GO:0033126 1 0.025
Human
regulation of biological quality GO:0065008 263 0.025
regulation of dna recombination GO:0000018 2 0.025
cell fate specification GO:0001708 68 0.025
response to wounding GO:0009611 116 0.025
Mouse
neural retina development GO:0003407 49 0.024
positive regulation of immune effector process GO:0002699 3 0.024
regulation of protein complex assembly GO:0043254 3 0.024
multicellular organism growth GO:0035264 4 0.024
regulation of intracellular signal transduction GO:1902531 57 0.024
Human
cell motility GO:0048870 244 0.024
positive regulation of biological process GO:0048518 253 0.024
Human
cellular response to dna damage stimulus GO:0006974 24 0.024
nucleobase containing compound transport GO:0015931 2 0.024
regulation of cell cycle g2 m phase transition GO:1902749 4 0.024
single organism reproductive process GO:0044702 40 0.024
Worm
purine ribonucleoside monophosphate catabolic process GO:0009169 4 0.024
system process GO:0003008 185 0.023
morphogenesis of an epithelium GO:0002009 333 0.023
positive regulation of cytosolic calcium ion concentration GO:0007204 4 0.023
phagocytosis GO:0006909 3 0.023
negative regulation of histone modification GO:0031057 1 0.023
regulation of cellular component organization GO:0051128 86 0.023
Human
muscle organ development GO:0007517 101 0.023
Fly
oxoacid metabolic process GO:0043436 31 0.023
developmental growth GO:0048589 166 0.023
Mouse
positive regulation of cellular amine metabolic process GO:0033240 0 0.023
heart morphogenesis GO:0003007 156 0.023
phosphate containing compound metabolic process GO:0006796 108 0.023
Human Mouse
digestive tract morphogenesis GO:0048546 231 0.023
regulation of nucleoside metabolic process GO:0009118 2 0.023
Human
mitotic g2 m transition checkpoint GO:0044818 3 0.022
meiotic nuclear division GO:0007126 4 0.022
positive regulation of cellular metabolic process GO:0031325 94 0.022
Human
g2 dna damage checkpoint GO:0031572 3 0.022
macromolecular complex assembly GO:0065003 35 0.022
chordate embryonic development GO:0043009 271 0.022
negative regulation of cell communication GO:0010648 96 0.022
Human
negative regulation of ras protein signal transduction GO:0046580 1 0.022
regulation of chromosome segregation GO:0051983 1 0.021
development of primary female sexual characteristics GO:0046545 4 0.021
g1 s transition of mitotic cell cycle GO:0000082 1 0.021
Mouse
negative regulation of chromatin modification GO:1903309 1 0.021
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 4 0.021
hematopoietic or lymphoid organ development GO:0048534 191 0.021
cellular response to chemical stimulus GO:0070887 157 0.021
Mouse
fertilization GO:0009566 3 0.021
regulation of dna replication GO:0006275 3 0.021
cell maturation GO:0048469 23 0.020
intracellular signal transduction GO:0035556 85 0.020
Human
epithelial cell morphogenesis GO:0003382 2 0.020
sensory organ morphogenesis GO:0090596 200 0.020
cell migration involved in gastrulation GO:0042074 79 0.020
positive regulation of gene expression GO:0010628 71 0.020
peptidyl amino acid modification GO:0018193 16 0.020
Fly
regulation of dendrite development GO:0050773 3 0.020
protein dephosphorylation GO:0006470 3 0.020
negative regulation of small gtpase mediated signal transduction GO:0051058 1 0.020
blood circulation GO:0008015 87 0.020
mitochondrion organization GO:0007005 4 0.020
pancreas development GO:0031016 84 0.020
cellular component assembly GO:0022607 170 0.020
meiosis i GO:0007127 1 0.020
positive regulation of dna metabolic process GO:0051054 1 0.020
compound eye development GO:0048749 2 0.020
regulation of gtp catabolic process GO:0033124 2 0.020
Human
response to nutrient GO:0007584 3 0.019
regulation of carbohydrate metabolic process GO:0006109 4 0.019
cellular response to oxygen levels GO:0071453 1 0.019
positive regulation of transcription from rna polymerase ii promoter GO:0045944 22 0.019
response to drug GO:0042493 3 0.019
retina morphogenesis in camera type eye GO:0060042 79 0.019
positive regulation of nucleic acid templated transcription GO:1903508 57 0.019
regionalization GO:0003002 274 0.019
cardiac muscle cell differentiation GO:0055007 30 0.019
regulation of carbohydrate biosynthetic process GO:0043255 1 0.019
regulation of organelle organization GO:0033043 29 0.019
regulation of leukocyte mediated immunity GO:0002703 1 0.018
developmental maturation GO:0021700 34 0.018
response to abiotic stimulus GO:0009628 122 0.018
negative regulation of histone methylation GO:0031061 1 0.018
b cell mediated immunity GO:0019724 3 0.018
eye morphogenesis GO:0048592 144 0.018
negative regulation of developmental process GO:0051093 65 0.018
Mouse Worm
negative regulation of protein kinase activity GO:0006469 4 0.018
localization of cell GO:0051674 244 0.018
mrna transport GO:0051028 2 0.018
non recombinational repair GO:0000726 2 0.018
establishment of rna localization GO:0051236 3 0.018
immunoglobulin production GO:0002377 1 0.018
circadian rhythm GO:0007623 19 0.018
Human Mouse
dna methylation GO:0006306 8 0.018
Mouse
epidermis development GO:0008544 48 0.017
Mouse
vasculature development GO:0001944 278 0.017
mitotic dna damage checkpoint GO:0044773 4 0.017
regulation of catalytic activity GO:0050790 55 0.017
Human
centrosome organization GO:0051297 1 0.017
regulation of cell cycle GO:0051726 52 0.017
Mouse
oocyte anterior posterior axis specification GO:0007314 4 0.017
chemotaxis GO:0006935 104 0.017
Fly
phosphorus metabolic process GO:0006793 109 0.017
Human Mouse
cellular response to stress GO:0033554 62 0.017
Mouse
fin regeneration GO:0031101 51 0.017
oocyte differentiation GO:0009994 14 0.017
cardiac muscle tissue development GO:0048738 48 0.017
ribonucleoside monophosphate catabolic process GO:0009158 4 0.017
negative regulation of reproductive process GO:2000242 3 0.017
cellular response to external stimulus GO:0071496 2 0.017
regulation of cytoskeleton organization GO:0051493 11 0.016
stem cell proliferation GO:0072089 4 0.016
response to amphetamine GO:0001975 1 0.016
regulation of cell activation GO:0050865 1 0.016
myosin filament organization GO:0031033 6 0.016
cardiac muscle cell development GO:0055013 20 0.016
cellular amino acid biosynthetic process GO:0008652 2 0.016
regulation of cell differentiation GO:0045595 142 0.016
Human Mouse
determination of left right symmetry GO:0007368 179 0.016
positive regulation of cellular catabolic process GO:0031331 3 0.016
Human
peptidyl lysine modification GO:0018205 5 0.016
Fly
liver development GO:0001889 96 0.016
heart contraction GO:0060047 71 0.016
double strand break repair GO:0006302 3 0.016
skeletal muscle tissue development GO:0007519 67 0.016
inner ear development GO:0048839 126 0.015
alpha amino acid metabolic process GO:1901605 3 0.015
response to ketone GO:1901654 1 0.015
organelle assembly GO:0070925 110 0.015
cardiac atrium morphogenesis GO:0003209 2 0.015
myofibril assembly GO:0030239 48 0.015
guanosine containing compound catabolic process GO:1901069 2 0.015
Human
multicellular organismal reproductive process GO:0048609 35 0.015
Worm
posttranscriptional gene silencing by rna GO:0035194 3 0.015
cellular response to extracellular stimulus GO:0031668 2 0.015
muscle cell differentiation GO:0042692 139 0.015
Mouse
nucleic acid transport GO:0050657 2 0.015
cytoplasm organization GO:0007028 4 0.015
regeneration GO:0031099 91 0.015
Mouse
embryonic pattern specification GO:0009880 44 0.015
translational initiation GO:0006413 3 0.015
regulation of cell shape GO:0008360 1 0.014
ras protein signal transduction GO:0007265 7 0.014
spermatid differentiation GO:0048515 2 0.014
peptidyl serine phosphorylation GO:0018105 1 0.014
double strand break repair via nonhomologous end joining GO:0006303 1 0.014
regulation of purine nucleotide catabolic process GO:0033121 2 0.014
Human
cellular carbohydrate metabolic process GO:0044262 4 0.014
cellular amino acid metabolic process GO:0006520 7 0.014
lymphocyte proliferation GO:0046651 1 0.014
striated muscle cell development GO:0055002 108 0.014
positive regulation of transcription dna templated GO:0045893 57 0.014
b cell activation GO:0042113 2 0.014
response to external biotic stimulus GO:0043207 97 0.014
extrinsic apoptotic signaling pathway in absence of ligand GO:0097192 1 0.014
single organism biosynthetic process GO:0044711 71 0.014
brain development GO:0007420 293 0.014
Mouse
posttranscriptional regulation of gene expression GO:0010608 14 0.014
negative regulation of protein phosphorylation GO:0001933 4 0.014
cartilage development GO:0051216 96 0.014
cellular catabolic process GO:0044248 27 0.014
Human
female gamete generation GO:0007292 14 0.013
oocyte development GO:0048599 14 0.013
regulation of binding GO:0051098 3 0.013
regulation of dna templated transcription elongation GO:0032784 3 0.013
Mouse
oocyte maturation GO:0001556 4 0.013
regulation of skeletal muscle tissue development GO:0048641 4 0.013
regulation of intracellular protein transport GO:0033157 3 0.013
mesenchyme development GO:0060485 127 0.013
Human
pronuclear migration GO:0035046 1 0.013
homeostatic process GO:0042592 142 0.013
blood vessel development GO:0001568 246 0.013
positive regulation of apoptotic signaling pathway GO:2001235 1 0.013
regulation of neurogenesis GO:0050767 87 0.013
Mouse
establishment of localization GO:0051234 244 0.013
regulation of extrinsic apoptotic signaling pathway in absence of ligand GO:2001239 1 0.013
gene silencing by rna GO:0031047 4 0.013
response to corticosteroid GO:0031960 1 0.013
negative regulation of dna replication GO:0008156 2 0.013
female gonad development GO:0008585 4 0.013
positive regulation of cellular component biogenesis GO:0044089 3 0.013
posttranscriptional gene silencing GO:0016441 3 0.012
positive regulation of catabolic process GO:0009896 4 0.012
Human
regulation of stem cell proliferation GO:0072091 2 0.012
lateral inhibition GO:0046331 1 0.012
cardiac cell development GO:0055006 21 0.012
cardiac atrium development GO:0003230 4 0.012
oxidation reduction process GO:0055114 41 0.012
positive regulation of cytoskeleton organization GO:0051495 3 0.012
negative regulation of meiotic cell cycle GO:0051447 1 0.012
chemosensory behavior GO:0007635 1 0.012
somatic cell dna recombination GO:0016444 1 0.012
oogenesis GO:0048477 14 0.012
cell surface receptor signaling pathway GO:0007166 325 0.012
cellular protein complex assembly GO:0043623 19 0.012
regulation of cellular protein metabolic process GO:0032268 52 0.012
Human Mouse
embryonic skeletal system development GO:0048706 97 0.012
antimicrobial humoral response GO:0019730 2 0.012
negative regulation of signal transduction GO:0009968 94 0.012
Human
morphogenesis of a branching structure GO:0001763 21 0.012
guanosine containing compound metabolic process GO:1901068 4 0.012
Human
negative regulation of multi organism process GO:0043901 3 0.012
ion homeostasis GO:0050801 41 0.011
cell cycle phase transition GO:0044770 9 0.011
Mouse
axis specification GO:0009798 43 0.011
blood vessel morphogenesis GO:0048514 216 0.011
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.011
modification dependent protein catabolic process GO:0019941 3 0.011
leukocyte proliferation GO:0070661 1 0.011
positive regulation of production of molecular mediator of immune response GO:0002702 1 0.011
negative regulation of cell differentiation GO:0045596 46 0.011
Mouse
spermatid development GO:0007286 2 0.011
peptidyl lysine acetylation GO:0018394 2 0.011
neurological system process GO:0050877 62 0.011
centrosome duplication GO:0051298 1 0.011
male meiosis GO:0007140 2 0.011
cell cycle arrest GO:0007050 1 0.011
response to nitrogen compound GO:1901698 19 0.011
positive regulation of metabolic process GO:0009893 108 0.011
Human
cellular response to organic substance GO:0071310 105 0.011
negative regulation of cellular catabolic process GO:0031330 3 0.011
germ cell development GO:0007281 22 0.011
Worm
cellular modified amino acid metabolic process GO:0006575 3 0.010
negative regulation of catabolic process GO:0009895 3 0.010
positive regulation of transcription elongation from rna polymerase ii promoter GO:0032968 1 0.010
regulation of calcium ion transport GO:0051924 2 0.010
regulation of molecular function GO:0065009 70 0.010
Human
mrna 3 end processing GO:0031124 2 0.010
actin filament based process GO:0030029 64 0.010
exocytosis GO:0006887 1 0.010
embryonic skeletal joint development GO:0072498 3 0.010
regulation of cellular protein catabolic process GO:1903362 1 0.010
response to glucocorticoid GO:0051384 1 0.010
signal transduction in absence of ligand GO:0038034 1 0.010
regulation of establishment of protein localization GO:0070201 4 0.010

ezh2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.015