Danio rerio

28 known processes

ezr

ezrin

(Aliases: wu:fc05c03,vil2,wu:fj31d06)

ezr biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cellular macromolecule metabolic process GO:0044260 391 0.753
Mouse Fly
protein metabolic process GO:0019538 183 0.381
Fly
cellular biosynthetic process GO:0044249 286 0.370
organelle organization GO:0006996 227 0.367
Human Worm Fly
nucleic acid metabolic process GO:0090304 244 0.315
signal transduction GO:0007165 455 0.285
regionalization GO:0003002 274 0.246
Fly
regulation of macromolecule biosynthetic process GO:0010556 225 0.243
cellular aromatic compound metabolic process GO:0006725 295 0.233
cytokinesis GO:0000910 3 0.229
Fly
organic substance biosynthetic process GO:1901576 289 0.209
biosynthetic process GO:0009058 294 0.205
regulation of primary metabolic process GO:0080090 311 0.201
negative regulation of cellular process GO:0048523 283 0.198
organic cyclic compound metabolic process GO:1901360 301 0.197
regulation of cellular metabolic process GO:0031323 320 0.191
cellular macromolecule biosynthetic process GO:0034645 224 0.186
cell motility GO:0048870 244 0.168
macromolecule biosynthetic process GO:0009059 227 0.151
cellular nitrogen compound metabolic process GO:0034641 290 0.147
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.142
organic cyclic compound biosynthetic process GO:1901362 223 0.134
heterocycle metabolic process GO:0046483 290 0.132
skin development GO:0043588 54 0.129
phosphorylation GO:0016310 69 0.128
single organism metabolic process GO:0044710 217 0.128
Mouse Fly
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.127
Fly
positive regulation of biological process GO:0048518 253 0.124
Human Fly
small molecule metabolic process GO:0044281 77 0.122
single organism cellular localization GO:1902580 46 0.122
Worm Fly
eye development GO:0001654 277 0.119
Fly
regulation of cell communication GO:0010646 232 0.109
larval development GO:0002164 2 0.096
Worm Fly
death GO:0016265 121 0.096
Worm
regulation of nitrogen compound metabolic process GO:0051171 251 0.095
nitrogen compound metabolic process GO:0006807 319 0.093
phosphate containing compound metabolic process GO:0006796 108 0.093
cell cycle GO:0007049 93 0.092
Fly
cell surface receptor signaling pathway GO:0007166 325 0.089
cellular protein metabolic process GO:0044267 129 0.082
Fly
regulation of metabolic process GO:0019222 359 0.080
Human
negative regulation of biological process GO:0048519 304 0.080
regulation of signal transduction GO:0009966 225 0.079
cell death GO:0008219 121 0.071
Worm
regulation of cellular component organization GO:0051128 86 0.069
Fly
nucleobase containing compound metabolic process GO:0006139 274 0.068
regulation of multicellular organismal development GO:2000026 223 0.067
meiotic nuclear division GO:0007126 4 0.065
single organism organelle organization GO:1902589 199 0.065
Human Worm Fly
cellular protein catabolic process GO:0044257 4 0.064
Fly
actin polymerization or depolymerization GO:0008154 2 0.063
leukocyte proliferation GO:0070661 1 0.062
generation of neurons GO:0048699 385 0.061
Fly
regulation of response to stimulus GO:0048583 269 0.060
epidermis development GO:0008544 48 0.059
regulation of gene expression GO:0010468 265 0.058
Human
cell growth GO:0016049 57 0.056
synaptic growth at neuromuscular junction GO:0051124 2 0.056
regulation of nucleic acid templated transcription GO:1903506 213 0.055
activation of immune response GO:0002253 9 0.054
protein polymerization GO:0051258 4 0.053
response to stress GO:0006950 263 0.053
regulation of protein metabolic process GO:0051246 56 0.052
epithelial cell differentiation GO:0030855 116 0.052
Human
transport GO:0006810 220 0.052
Mouse Worm Fly
regulation of macromolecule metabolic process GO:0060255 317 0.052
Human
organic acid metabolic process GO:0006082 31 0.050
single organism localization GO:1902578 225 0.050
Mouse Worm Fly
response to nutrient GO:0007584 3 0.049
phagocytosis GO:0006909 3 0.049
mononuclear cell proliferation GO:0032943 1 0.049
muscle cell development GO:0055001 115 0.049
Worm
cell division GO:0051301 20 0.048
Fly
maintenance of location GO:0051235 4 0.047
organonitrogen compound metabolic process GO:1901564 74 0.045
gene expression GO:0010467 252 0.045
Human
cell projection organization GO:0030030 284 0.044
Fly
protein localization GO:0008104 40 0.044
Worm
cellular nitrogen compound biosynthetic process GO:0044271 218 0.044
dorsal ventral pattern formation GO:0009953 125 0.043
carboxylic acid metabolic process GO:0019752 22 0.043
digestive tract development GO:0048565 265 0.043
positive regulation of cellular metabolic process GO:0031325 94 0.043
organonitrogen compound biosynthetic process GO:1901566 47 0.042
actin filament polymerization GO:0030041 2 0.042
protein localization to membrane GO:0072657 9 0.042
Worm
intracellular signal transduction GO:0035556 85 0.042
protein import GO:0017038 3 0.041
cellular component morphogenesis GO:0032989 336 0.041
Worm Fly
striated muscle tissue development GO:0014706 110 0.041
regulation of protein import into nucleus GO:0042306 2 0.040
regulation of intracellular protein transport GO:0033157 3 0.040
heterocycle biosynthetic process GO:0018130 215 0.040
actin filament based process GO:0030029 64 0.039
Human Worm Fly
multicellular organism reproduction GO:0032504 35 0.038
Fly
response to organic substance GO:0010033 153 0.037
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.037
regulation of rna biosynthetic process GO:2001141 213 0.037
alpha amino acid metabolic process GO:1901605 3 0.037
enzyme linked receptor protein signaling pathway GO:0007167 106 0.036
inner ear development GO:0048839 126 0.036
response to virus GO:0009615 21 0.036
cell morphogenesis involved in differentiation GO:0000904 195 0.036
Fly
adult behavior GO:0030534 2 0.035
sensory organ development GO:0007423 393 0.035
Fly
carbohydrate derivative metabolic process GO:1901135 61 0.035
antimicrobial humoral response GO:0019730 2 0.035
multi organism reproductive process GO:0044703 36 0.035
Fly
positive regulation of immune effector process GO:0002699 3 0.035
aromatic compound biosynthetic process GO:0019438 217 0.034
protein localization to plasma membrane GO:0072659 1 0.033
Worm
regulation of immune response GO:0050776 14 0.033
post golgi vesicle mediated transport GO:0006892 1 0.032
locomotor rhythm GO:0045475 3 0.032
phosphorus metabolic process GO:0006793 109 0.032
negative regulation of signal transduction GO:0009968 94 0.032
vasculature development GO:0001944 278 0.032
Zebrafish
regulation of cellular biosynthetic process GO:0031326 245 0.031
organism emergence from protective structure GO:0071684 4 0.031
positive regulation of macromolecule biosynthetic process GO:0010557 59 0.031
regulation of transcription dna templated GO:0006355 213 0.031
regulation of production of molecular mediator of immune response GO:0002700 1 0.031
regulation of metal ion transport GO:0010959 4 0.030
cell proliferation GO:0008283 80 0.030
Fly
regulation of biosynthetic process GO:0009889 250 0.030
regulation of transcription elongation from rna polymerase ii promoter GO:0034243 3 0.029
rna metabolic process GO:0016070 219 0.029
locomotion GO:0040011 313 0.029
apoptotic process GO:0006915 116 0.029
Worm
single organism nuclear import GO:1902593 3 0.029
establishment of localization in cell GO:0051649 77 0.028
Fly
transcription dna templated GO:0006351 181 0.028
carbohydrate derivative biosynthetic process GO:1901137 43 0.028
regulation of cell motility GO:2000145 46 0.028
zinc ion transport GO:0006829 2 0.027
transcription from rna polymerase ii promoter GO:0006366 80 0.027
regulation of locomotion GO:0040012 55 0.026
positive regulation of rna metabolic process GO:0051254 59 0.026
developmental process involved in reproduction GO:0003006 27 0.026
Fly
toxin transport GO:1901998 2 0.026
positive regulation of cellular biosynthetic process GO:0031328 68 0.025
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.025
cellular component assembly GO:0022607 170 0.025
Human Worm Fly
positive regulation of cell cycle GO:0045787 3 0.024
positive regulation of stress activated protein kinase signaling cascade GO:0070304 3 0.024
regulation of cytoplasmic transport GO:1903649 4 0.024
cellular amino acid biosynthetic process GO:0008652 2 0.024
rna biosynthetic process GO:0032774 181 0.024
regulation of protein transport GO:0051223 3 0.023
positive regulation of nucleic acid templated transcription GO:1903508 57 0.023
fertilization GO:0009566 3 0.023
organelle assembly GO:0070925 110 0.023
Worm
b cell activation GO:0042113 2 0.023
s adenosylmethionine metabolic process GO:0046500 1 0.023
phagocytosis engulfment GO:0006911 1 0.023
regulation of cell activation GO:0050865 1 0.022
oxoacid metabolic process GO:0043436 31 0.022
cellular amino acid metabolic process GO:0006520 7 0.022
lymphocyte proliferation GO:0046651 1 0.022
sensory perception GO:0007600 39 0.022
regulation of signaling GO:0023051 235 0.022
purine containing compound metabolic process GO:0072521 29 0.022
peptide metabolic process GO:0006518 1 0.022
hematopoietic or lymphoid organ development GO:0048534 191 0.021
neuron differentiation GO:0030182 353 0.021
Fly
aging GO:0007568 2 0.021
Worm
nucleocytoplasmic transport GO:0006913 4 0.021
positive regulation of multi organism process GO:0043902 3 0.021
regulation of cytoskeleton organization GO:0051493 11 0.021
Fly
cellular localization GO:0051641 97 0.021
Worm Fly
nuclear migration GO:0007097 3 0.021
regulation of protein complex assembly GO:0043254 3 0.020
developmental growth GO:0048589 166 0.020
positive regulation of transport GO:0051050 2 0.020
Fly
cellular response to extracellular stimulus GO:0031668 2 0.020
response to external stimulus GO:0009605 264 0.020
Fly
gtp catabolic process GO:0006184 2 0.020
cellular component movement GO:0006928 335 0.020
modification dependent macromolecule catabolic process GO:0043632 3 0.020
Fly
positive regulation of transcription dna templated GO:0045893 57 0.020
macromolecule modification GO:0043412 111 0.020
cell part morphogenesis GO:0032990 246 0.020
Fly
response to drug GO:0042493 3 0.020
gtp metabolic process GO:0046039 4 0.019
regulation of erk1 and erk2 cascade GO:0070372 4 0.019
cell migration GO:0016477 237 0.019
positive regulation of cellular component biogenesis GO:0044089 3 0.019
protein import into nucleus GO:0006606 3 0.019
response to chemical GO:0042221 320 0.019
Fly
regulation of establishment of protein localization GO:0070201 4 0.019
ventricular cardiac muscle tissue development GO:0003229 3 0.019
system process GO:0003008 185 0.018
triglyceride homeostasis GO:0070328 2 0.018
cellular modified amino acid metabolic process GO:0006575 3 0.018
neuron projection extension GO:1990138 45 0.018
cellular response to chemical stimulus GO:0070887 157 0.018
cellular response to stress GO:0033554 62 0.018
regulation of phosphorylation GO:0042325 26 0.018
regulation of nucleocytoplasmic transport GO:0046822 2 0.018
lamellipodium assembly GO:0030032 1 0.018
axon extension GO:0048675 45 0.018
germ cell development GO:0007281 22 0.018
Fly
positive regulation of protein metabolic process GO:0051247 23 0.017
specification of symmetry GO:0009799 204 0.017
Fly
negative regulation of response to stimulus GO:0048585 104 0.017
actin cytoskeleton organization GO:0030036 63 0.017
Human Worm Fly
negative regulation of protein phosphorylation GO:0001933 4 0.017
cortical actin cytoskeleton organization GO:0030866 1 0.017
Fly
negative regulation of protein kinase activity GO:0006469 4 0.017
multi organism process GO:0051704 134 0.017
Fly
regulation of cell growth GO:0001558 29 0.017
regulation of biological quality GO:0065008 263 0.017
Fly
amine metabolic process GO:0009308 2 0.016
regulation of transcription from rna polymerase ii promoter GO:0006357 114 0.016
positive regulation of response to stimulus GO:0048584 80 0.016
myotube differentiation GO:0014902 45 0.016
nuclear import GO:0051170 3 0.016
nucleoside monophosphate catabolic process GO:0009125 4 0.016
positive regulation of metabolic process GO:0009893 108 0.016
Human
positive regulation of cellular process GO:0048522 201 0.016
Fly
reproduction GO:0000003 40 0.016
Worm Fly
positive regulation of macromolecule metabolic process GO:0010604 93 0.016
Human
hemopoiesis GO:0030097 183 0.016
positive regulation of nucleobase containing compound metabolic process GO:0045935 69 0.016
long chain fatty acid metabolic process GO:0001676 1 0.015
cellular process involved in reproduction in multicellular organism GO:0022412 28 0.015
Fly
protein localization to nucleus GO:0034504 3 0.015
circulatory system process GO:0003013 87 0.015
establishment of protein localization to organelle GO:0072594 4 0.015
cytoskeleton organization GO:0007010 96 0.015
Human Worm Fly
cellular protein modification process GO:0006464 100 0.015
meiotic cell cycle process GO:1903046 3 0.015
negative regulation of multicellular organismal process GO:0051241 69 0.015
organophosphate metabolic process GO:0019637 37 0.015
cell morphogenesis GO:0000902 289 0.015
Fly
axis specification GO:0009798 43 0.015
Fly
carboxylic acid biosynthetic process GO:0046394 12 0.015
regulation of cell size GO:0008361 29 0.015
regulation of anatomical structure morphogenesis GO:0022603 130 0.014
cofactor metabolic process GO:0051186 15 0.014
positive regulation of signal transduction GO:0009967 56 0.014
response to wounding GO:0009611 116 0.014
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 2 0.014
nucleoside metabolic process GO:0009116 11 0.014
localization of cell GO:0051674 244 0.014
b cell proliferation GO:0042100 1 0.014
regulation of dendrite morphogenesis GO:0048814 3 0.014
biological adhesion GO:0022610 40 0.014
Human
epithelial cell morphogenesis GO:0003382 2 0.014
epiboly GO:0090504 41 0.014
neural nucleus development GO:0048857 15 0.014
dna templated transcription elongation GO:0006354 3 0.014
negative regulation of stem cell differentiation GO:2000737 2 0.013
regulation of multicellular organismal process GO:0051239 277 0.013
positive regulation of jnk cascade GO:0046330 3 0.013
regulation of cellular protein metabolic process GO:0032268 52 0.013
myeloid cell homeostasis GO:0002262 56 0.013
embryonic organ development GO:0048568 381 0.013
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.013
Fly
small molecule biosynthetic process GO:0044283 16 0.013
establishment of localization GO:0051234 244 0.013
Mouse Worm Fly
nucleoside phosphate metabolic process GO:0006753 28 0.013
protein modification process GO:0036211 100 0.013
immune system process GO:0002376 241 0.013
digestive system development GO:0055123 289 0.013
regulation of cellular amine metabolic process GO:0033238 0 0.013
morphogenesis of an epithelial sheet GO:0002011 49 0.013
stem cell development GO:0048864 82 0.013
regulation of dendrite development GO:0050773 3 0.012
hepaticobiliary system development GO:0061008 98 0.012
programmed cell death GO:0012501 119 0.012
Worm
cellular amide metabolic process GO:0043603 4 0.012
positive regulation of biosynthetic process GO:0009891 68 0.012
protein targeting to nucleus GO:0044744 3 0.012
oocyte differentiation GO:0009994 14 0.012
Fly
regulation of rna metabolic process GO:0051252 224 0.012
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.012
response to inorganic substance GO:0010035 38 0.012
negative regulation of signaling GO:0023057 96 0.012
cellular ketone metabolic process GO:0042180 11 0.012
production of molecular mediator of immune response GO:0002440 2 0.012
endosome organization GO:0007032 2 0.012
hatching GO:0035188 4 0.012
cellular component biogenesis GO:0044085 178 0.012
Human Worm Fly
homeostatic process GO:0042592 142 0.012
negative regulation of i kappab kinase nf kappab signaling GO:0043124 1 0.012
regulation of phosphate metabolic process GO:0019220 43 0.012
guanosine containing compound metabolic process GO:1901068 4 0.012
metal ion transport GO:0030001 58 0.012
regulation of cell migration GO:0030334 40 0.011
regulation of response to biotic stimulus GO:0002831 2 0.011
regulation of reproductive process GO:2000241 4 0.011
erk1 and erk2 cascade GO:0070371 4 0.011
single fertilization GO:0007338 3 0.011
positive regulation of stress activated mapk cascade GO:0032874 3 0.011
ion transport GO:0006811 114 0.011
intracellular transport GO:0046907 32 0.011
regulation of growth GO:0040008 42 0.011
regulation of apoptotic process GO:0042981 98 0.011
mitotic cell cycle GO:0000278 64 0.011
Fly
regulation of cellular amino acid metabolic process GO:0006521 0 0.010
heart development GO:0007507 313 0.010
proteasomal protein catabolic process GO:0010498 2 0.010
Fly
regulation of protein catabolic process GO:0042176 1 0.010
convergent extension GO:0060026 118 0.010
taxis GO:0042330 109 0.010
Fly
regulation of cell morphogenesis GO:0022604 42 0.010
catabolic process GO:0009056 32 0.010
Fly
nuclear transport GO:0051169 4 0.010

ezr disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.016
disease of metabolism DOID:0014667 0 0.011
inherited metabolic disorder DOID:655 0 0.011