Danio rerio

0 known processes

fanca

Fanconi anemia, complementation group A

fanca biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
segmentation GO:0035282 97 0.279
anterior posterior pattern specification GO:0009952 152 0.265
cellular macromolecule metabolic process GO:0044260 391 0.181
nitrogen compound metabolic process GO:0006807 319 0.119
maintenance of location GO:0051235 4 0.119
multicellular organism growth GO:0035264 4 0.103
somitogenesis GO:0001756 87 0.089
regulation of nucleic acid templated transcription GO:1903506 213 0.087
carboxylic acid metabolic process GO:0019752 22 0.084
somite development GO:0061053 96 0.078
stem cell maintenance GO:0019827 4 0.078
regulation of transcription dna templated GO:0006355 213 0.078
membrane hyperpolarization GO:0060081 1 0.075
regulation of reproductive process GO:2000241 4 0.074
regulation of biosynthetic process GO:0009889 250 0.074
nucleic acid metabolic process GO:0090304 244 0.071
hindbrain morphogenesis GO:0021575 22 0.071
response to abiotic stimulus GO:0009628 122 0.069
negative regulation of apoptotic process GO:0043066 55 0.067
embryo development ending in birth or egg hatching GO:0009792 271 0.067
single organism transport GO:0044765 206 0.064
multi organism process GO:0051704 134 0.060
cellular biosynthetic process GO:0044249 286 0.057
localization of cell GO:0051674 244 0.056
regulation of postsynaptic membrane potential GO:0060078 1 0.055
transcription dna templated GO:0006351 181 0.054
chordate embryonic development GO:0043009 271 0.052
regulation of mrna processing GO:0050684 3 0.052
programmed cell death GO:0012501 119 0.051
eye morphogenesis GO:0048592 144 0.049
cell death GO:0008219 121 0.049
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.049
regulation of fatty acid metabolic process GO:0019217 1 0.047
response to stress GO:0006950 263 0.047
regulation of apoptotic process GO:0042981 98 0.044
histone modification GO:0016570 20 0.044
regulation of programmed cell death GO:0043067 101 0.044
cellular macromolecule biosynthetic process GO:0034645 224 0.043
positive regulation of biological process GO:0048518 253 0.043
female sex differentiation GO:0046660 4 0.042
cellular response to oxygen levels GO:0071453 1 0.041
long chain fatty acid transport GO:0015909 1 0.041
rna biosynthetic process GO:0032774 181 0.038
aging GO:0007568 2 0.038
rna metabolic process GO:0016070 219 0.038
chromosome organization GO:0051276 31 0.038
positive regulation of translation GO:0045727 1 0.038
regionalization GO:0003002 274 0.037
blood vessel morphogenesis GO:0048514 216 0.036
histone lysine methylation GO:0034968 12 0.036
cell substrate adhesion GO:0031589 4 0.035
cellular response to stress GO:0033554 62 0.035
reactive oxygen species metabolic process GO:0072593 6 0.035
embryonic digestive tract development GO:0048566 4 0.035
nucleobase containing compound biosynthetic process GO:0034654 205 0.035
regulation of mrna catabolic process GO:0061013 3 0.035
smooth muscle contraction GO:0006939 2 0.035
organonitrogen compound metabolic process GO:1901564 74 0.034
regulation of oligodendrocyte differentiation GO:0048713 1 0.034
proximal distal pattern formation GO:0009954 1 0.033
camera type eye morphogenesis GO:0048593 108 0.033
post embryonic morphogenesis GO:0009886 4 0.033
protein metabolic process GO:0019538 183 0.032
central nervous system development GO:0007417 387 0.032
cellular aromatic compound metabolic process GO:0006725 295 0.032
reproductive process GO:0022414 40 0.032
regulation of ion transmembrane transporter activity GO:0032412 2 0.032
nucleobase containing compound metabolic process GO:0006139 274 0.031
positive regulation of macromolecule biosynthetic process GO:0010557 59 0.030
specification of axis polarity GO:0065001 4 0.030
muscle cell differentiation GO:0042692 139 0.030
macromolecule biosynthetic process GO:0009059 227 0.029
acylglycerol homeostasis GO:0055090 2 0.029
regulation of cell development GO:0060284 100 0.029
embryonic heart tube development GO:0035050 133 0.029
regulation of cytokine production GO:0001817 3 0.028
regulation of rna biosynthetic process GO:2001141 213 0.028
response to nutrient GO:0007584 3 0.028
alternative mrna splicing via spliceosome GO:0000380 1 0.028
hemopoiesis GO:0030097 183 0.027
regulation of inflammatory response GO:0050727 2 0.027
organic cyclic compound metabolic process GO:1901360 301 0.026
polarized epithelial cell differentiation GO:0030859 4 0.026
histone methylation GO:0016571 13 0.026
lipid oxidation GO:0034440 1 0.025
single organism organelle organization GO:1902589 199 0.025
response to vitamin GO:0033273 3 0.025
meiosis i GO:0007127 1 0.025
negative regulation of cytokine production GO:0001818 1 0.025
positive regulation of cell division GO:0051781 2 0.025
cell motility GO:0048870 244 0.024
negative regulation of biological process GO:0048519 304 0.024
regulation of transmembrane transporter activity GO:0022898 2 0.024
olfactory bulb development GO:0021772 4 0.024
aromatic compound biosynthetic process GO:0019438 217 0.024
brain development GO:0007420 293 0.023
dna biosynthetic process GO:0071897 3 0.023
angiogenesis GO:0001525 158 0.023
nucleic acid templated transcription GO:0097659 181 0.023
heart morphogenesis GO:0003007 156 0.023
regulation of response to stimulus GO:0048583 269 0.023
development of primary female sexual characteristics GO:0046545 4 0.023
regulation of inhibitory postsynaptic membrane potential GO:0060080 1 0.022
regulation of cell death GO:0010941 103 0.022
apoptotic process GO:0006915 116 0.022
regulation of cellular carbohydrate metabolic process GO:0010675 4 0.022
negative regulation of cell death GO:0060548 60 0.022
death GO:0016265 121 0.022
regulation of cell maturation GO:1903429 1 0.022
hormone transport GO:0009914 2 0.022
organic acid metabolic process GO:0006082 31 0.022
spermatid differentiation GO:0048515 2 0.022
cation transmembrane transport GO:0098655 65 0.022
cell migration GO:0016477 237 0.021
eye development GO:0001654 277 0.021
cellular response to dna damage stimulus GO:0006974 24 0.021
establishment of protein localization to organelle GO:0072594 4 0.020
regulation of stem cell differentiation GO:2000736 4 0.020
regulation of transcription from rna polymerase ii promoter GO:0006357 114 0.020
spermatid development GO:0007286 2 0.020
generation of neurons GO:0048699 385 0.020
regulation of macromolecule biosynthetic process GO:0010556 225 0.020
morphogenesis of an epithelium GO:0002009 333 0.020
single organism metabolic process GO:0044710 217 0.020
canonical wnt signaling pathway GO:0060070 48 0.019
multi organism reproductive process GO:0044703 36 0.019
negative regulation of metabolic process GO:0009892 86 0.019
cellular amino acid metabolic process GO:0006520 7 0.019
regulation of nitrogen compound metabolic process GO:0051171 251 0.019
negative regulation of programmed cell death GO:0043069 58 0.019
leukocyte differentiation GO:0002521 25 0.019
regulation of cellular metabolic process GO:0031323 320 0.019
regulation of stem cell proliferation GO:0072091 2 0.019
response to external biotic stimulus GO:0043207 97 0.019
regulation of rna metabolic process GO:0051252 224 0.019
ribosomal small subunit biogenesis GO:0042274 2 0.018
regulation of oocyte development GO:0060281 3 0.018
positive regulation of cell cycle GO:0045787 3 0.018
biosynthetic process GO:0009058 294 0.018
wnt signaling pathway GO:0016055 80 0.018
hypothalamus cell differentiation GO:0021979 4 0.018
l amino acid transport GO:0015807 1 0.018
sister chromatid cohesion GO:0007062 2 0.018
cellular nitrogen compound biosynthetic process GO:0044271 218 0.018
response to wounding GO:0009611 116 0.018
regulation of wnt signaling pathway GO:0030111 53 0.018
embryonic organ morphogenesis GO:0048562 274 0.018
neutral amino acid transport GO:0015804 2 0.018
regulation of cellular biosynthetic process GO:0031326 245 0.017
larval development GO:0002164 2 0.017
chromatin organization GO:0006325 22 0.017
oxoacid metabolic process GO:0043436 31 0.017
retina layer formation GO:0010842 24 0.017
establishment of localization GO:0051234 244 0.017
embryonic heart tube morphogenesis GO:0003143 108 0.017
reproduction GO:0000003 40 0.016
positive regulation of cellular catabolic process GO:0031331 3 0.016
positive regulation of cellular biosynthetic process GO:0031328 68 0.016
fatty acid catabolic process GO:0009062 1 0.016
regulation of multicellular organism growth GO:0040014 4 0.016
cellular response to chemical stimulus GO:0070887 157 0.016
regulation of localization GO:0032879 104 0.016
skeletal muscle organ development GO:0060538 78 0.016
cell cycle GO:0007049 93 0.016
superoxide metabolic process GO:0006801 2 0.016
regulation of membrane potential GO:0042391 23 0.015
alpha amino acid metabolic process GO:1901605 3 0.015
muscle cell development GO:0055001 115 0.015
digestive system development GO:0055123 289 0.015
regulation of multicellular organismal process GO:0051239 277 0.015
sexual reproduction GO:0019953 36 0.015
cellular response to hypoxia GO:0071456 1 0.015
organic substance biosynthetic process GO:1901576 289 0.015
regulation of cell activation GO:0050865 1 0.015
response to inorganic substance GO:0010035 38 0.015
positive regulation of epithelial cell differentiation GO:0030858 2 0.015
positive regulation of stem cell proliferation GO:2000648 1 0.014
posttranscriptional gene silencing GO:0016441 3 0.014
heterocycle metabolic process GO:0046483 290 0.014
transcription from rna polymerase ii promoter GO:0006366 80 0.014
positive regulation of catabolic process GO:0009896 4 0.014
negative regulation of hormone secretion GO:0046888 2 0.014
regulation of cell shape GO:0008360 1 0.014
positive regulation of nucleobase containing compound metabolic process GO:0045935 69 0.014
regulation of mrna splicing via spliceosome GO:0048024 3 0.014
embryonic digestive tract morphogenesis GO:0048557 3 0.014
regulation of response to external stimulus GO:0032101 31 0.014
striated muscle cell differentiation GO:0051146 129 0.014
cellular response to extracellular stimulus GO:0031668 2 0.014
transport GO:0006810 220 0.014
response to alkaloid GO:0043279 2 0.014
regulation of alternative mrna splicing via spliceosome GO:0000381 1 0.014
metencephalon development GO:0022037 27 0.014
regulation of multicellular organismal development GO:2000026 223 0.014
peptide transport GO:0015833 1 0.014
neuron neuron synaptic transmission GO:0007270 1 0.014
embryonic organ development GO:0048568 381 0.013
cellular response to organic cyclic compound GO:0071407 38 0.013
regulation of homeostatic process GO:0032844 9 0.013
cytoplasm organization GO:0007028 4 0.013
cellular protein metabolic process GO:0044267 129 0.013
zinc ion transport GO:0006829 2 0.013
positive regulation of gene expression GO:0010628 71 0.013
negative regulation of cellular process GO:0048523 283 0.013
positive regulation of metabolic process GO:0009893 108 0.013
heterocycle biosynthetic process GO:0018130 215 0.013
determination of heart left right asymmetry GO:0061371 117 0.013
protein alkylation GO:0008213 13 0.013
negative regulation of mrna metabolic process GO:1903312 3 0.013
regulation of gene expression GO:0010468 265 0.013
regulation of endothelial cell differentiation GO:0045601 3 0.013
cellular component assembly GO:0022607 170 0.013
sensory organ morphogenesis GO:0090596 200 0.013
cellular response to nutrient levels GO:0031669 2 0.013
cellular response to starvation GO:0009267 1 0.013
glucose homeostasis GO:0042593 1 0.013
developmental growth GO:0048589 166 0.012
multicellular organismal reproductive process GO:0048609 35 0.012
immune system development GO:0002520 191 0.012
endosome to lysosome transport GO:0008333 1 0.012
positive regulation of mrna metabolic process GO:1903313 2 0.012
regulation of cell differentiation GO:0045595 142 0.012
positive regulation of cytokine production GO:0001819 2 0.012
single organism localization GO:1902578 225 0.012
regulation of metal ion transport GO:0010959 4 0.012
pole plasm assembly GO:0007315 4 0.012
mitotic cytokinesis GO:0000281 3 0.012
vasculature development GO:0001944 278 0.012
retina morphogenesis in camera type eye GO:0060042 79 0.012
amino acid transport GO:0006865 2 0.012
antimicrobial humoral response GO:0019730 2 0.012
response to bacterium GO:0009617 58 0.012
regulation of cellular ketone metabolic process GO:0010565 7 0.012
specification of symmetry GO:0009799 204 0.012
anterior posterior axis specification GO:0009948 20 0.012
endosomal transport GO:0016197 2 0.012
cytoskeleton dependent cytokinesis GO:0061640 3 0.012
muscle cell migration GO:0014812 4 0.011
production of molecular mediator of immune response GO:0002440 2 0.011
response to biotic stimulus GO:0009607 97 0.011
gene silencing by rna GO:0031047 4 0.011
digestive system process GO:0022600 9 0.011
determination of bilateral symmetry GO:0009855 204 0.011
negative regulation of immune response GO:0050777 2 0.011
hematopoietic or lymphoid organ development GO:0048534 191 0.011
negative regulation of nitrogen compound metabolic process GO:0051172 59 0.011
positive regulation of biosynthetic process GO:0009891 68 0.011
cellular response to external stimulus GO:0071496 2 0.011
cellular amine metabolic process GO:0044106 2 0.011
cellular component morphogenesis GO:0032989 336 0.011
nitric oxide biosynthetic process GO:0006809 2 0.011
single organism reproductive process GO:0044702 40 0.011
response to chemical GO:0042221 320 0.011
lymphocyte activation GO:0046649 10 0.011
cell proliferation in hindbrain GO:0021534 4 0.011
cellular modified amino acid metabolic process GO:0006575 3 0.011
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.011
carbohydrate homeostasis GO:0033500 1 0.011
stem cell fate commitment GO:0048865 1 0.011
positive regulation of macromolecule metabolic process GO:0010604 93 0.010
neuron development GO:0048666 262 0.010
nucleocytoplasmic transport GO:0006913 4 0.010
nuclear import GO:0051170 3 0.010
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.010
small molecule metabolic process GO:0044281 77 0.010
protein modification process GO:0036211 100 0.010
signal transduction GO:0007165 455 0.010
b cell differentiation GO:0030183 1 0.010
autophagy GO:0006914 4 0.010
ovarian follicle development GO:0001541 2 0.010
locomotion GO:0040011 313 0.010
rna stabilization GO:0043489 4 0.010
heart looping GO:0001947 94 0.010
positive regulation of transcription from rna polymerase ii promoter GO:0045944 22 0.010
regulation of skeletal muscle tissue development GO:0048641 4 0.010
hormone mediated signaling pathway GO:0009755 9 0.010
regulation of cellular amino acid metabolic process GO:0006521 0 0.010
heart development GO:0007507 313 0.010
regulation of carbohydrate metabolic process GO:0006109 4 0.010
positive regulation of canonical wnt signaling pathway GO:0090263 4 0.010
positive regulation of transport GO:0051050 2 0.010
defense response to other organism GO:0098542 33 0.010
posttranscriptional gene silencing by rna GO:0035194 3 0.010

fanca disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
congenital hypoplastic anemia DOID:1342 0 0.749
immune system disease DOID:2914 0 0.749
aplastic anemia DOID:12449 0 0.749
disease of anatomical entity DOID:7 0 0.749
fanconi s anemia DOID:13636 0 0.749
bone marrow disease DOID:4961 0 0.749
anemia DOID:2355 0 0.749
hematopoietic system disease DOID:74 0 0.749
disease of metabolism DOID:0014667 0 0.026
disease of cellular proliferation DOID:14566 0 0.023
amino acid metabolic disorder DOID:9252 0 0.013
inherited metabolic disorder DOID:655 0 0.013
musculoskeletal system disease DOID:17 0 0.013