Danio rerio

18 known processes

fbxw11a

F-box and WD-40 domain protein 11a

(Aliases: wu:fd14d12,fbxw11,wu:fi43f07,fbxw11b,fbxw1b,btrc2)

fbxw11a biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
signal transduction GO:0007165 455 0.374
Mouse Fly
larval development GO:0002164 2 0.209
Worm
ubiquitin dependent protein catabolic process GO:0006511 3 0.208
Human Mouse
cellular protein catabolic process GO:0044257 4 0.191
Human Mouse
cellular macromolecule metabolic process GO:0044260 391 0.112
Human Mouse Fly
regulation of metabolic process GO:0019222 359 0.103
Human Mouse Fly
cell projection assembly GO:0030031 64 0.093
regulation of signaling GO:0023051 235 0.092
Mouse Fly
organic substance biosynthetic process GO:1901576 289 0.091
Human Mouse
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.089
Human Mouse
modification dependent protein catabolic process GO:0019941 3 0.087
Human Mouse
negative regulation of cellular process GO:0048523 283 0.087
Human Mouse Worm Fly
meiotic cell cycle process GO:1903046 3 0.086
locomotion GO:0040011 313 0.086
Worm Fly
nitrogen compound metabolic process GO:0006807 319 0.084
Human Mouse Fly
convergent extension GO:0060026 118 0.082
cellular macromolecule biosynthetic process GO:0034645 224 0.081
Human Mouse
aging GO:0007568 2 0.077
Worm
organic cyclic compound biosynthetic process GO:1901362 223 0.077
Human Mouse
digestive tract development GO:0048565 265 0.074
regulation of macromolecule metabolic process GO:0060255 317 0.073
Human Mouse Fly
heterocycle biosynthetic process GO:0018130 215 0.068
Human Mouse
cellular component morphogenesis GO:0032989 336 0.067
Worm Fly
biosynthetic process GO:0009058 294 0.067
Human Mouse
regulation of protein catabolic process GO:0042176 1 0.066
digestive system development GO:0055123 289 0.065
regionalization GO:0003002 274 0.064
tube morphogenesis GO:0035239 349 0.064
regulation of multicellular organism growth GO:0040014 4 0.061
cellular component assembly GO:0022607 170 0.060
Fly
protein import GO:0017038 3 0.060
Mouse Fly
regulation of nitrogen compound metabolic process GO:0051171 251 0.059
Human Mouse Fly
heterocycle metabolic process GO:0046483 290 0.058
Human Mouse Fly
protein localization to nucleus GO:0034504 3 0.057
Mouse Fly
response to stress GO:0006950 263 0.057
meiosis i GO:0007127 1 0.056
intracellular signal transduction GO:0035556 85 0.055
Mouse Fly
aromatic compound biosynthetic process GO:0019438 217 0.054
Human Mouse
cellular aromatic compound metabolic process GO:0006725 295 0.054
Human Mouse Fly
negative regulation of biological process GO:0048519 304 0.054
Human Mouse Worm Fly
establishment of localization GO:0051234 244 0.054
Mouse Worm Fly
single organism metabolic process GO:0044710 217 0.053
Fly
cell part morphogenesis GO:0032990 246 0.051
Worm
nuclear transport GO:0051169 4 0.051
Mouse Fly
specification of symmetry GO:0009799 204 0.050
rna metabolic process GO:0016070 219 0.050
Human Mouse
regulation of macromolecule biosynthetic process GO:0010556 225 0.049
Human Mouse
positive regulation of transport GO:0051050 2 0.049
Fly
nucleic acid templated transcription GO:0097659 181 0.049
Human Mouse
nucleobase containing compound metabolic process GO:0006139 274 0.048
Human Mouse Fly
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.048
Human Mouse
phagocytosis GO:0006909 3 0.048
gastrulation GO:0007369 208 0.047
wnt signaling pathway GO:0016055 80 0.045
Fly
multicellular organism growth GO:0035264 4 0.045
apoptotic process GO:0006915 116 0.044
Fly
protein metabolic process GO:0019538 183 0.044
Human Mouse Fly
regulation of developmental process GO:0050793 247 0.043
Fly
regulation of biosynthetic process GO:0009889 250 0.043
Human Mouse
regulation of protein localization to nucleus GO:1900180 2 0.043
Mouse Fly
regulation of multicellular organismal process GO:0051239 277 0.042
Fly
embryo development ending in birth or egg hatching GO:0009792 271 0.042
Worm
cellular nitrogen compound biosynthetic process GO:0044271 218 0.042
Human Mouse
nuclear import GO:0051170 3 0.042
Mouse Fly
morphogenesis of an epithelium GO:0002009 333 0.042
Fly
nucleic acid metabolic process GO:0090304 244 0.041
Human Mouse Fly
cellular biosynthetic process GO:0044249 286 0.040
Human Mouse
regulation of protein transport GO:0051223 3 0.039
Mouse Fly
regulation of reproductive process GO:2000241 4 0.039
Fly
response to chemical GO:0042221 320 0.039
Fly
cell morphogenesis GO:0000902 289 0.039
Worm Fly
positive regulation of biological process GO:0048518 253 0.038
Human Mouse Fly
mitotic dna integrity checkpoint GO:0044774 4 0.038
lateral inhibition GO:0046331 1 0.037
brain development GO:0007420 293 0.037
digestive tract morphogenesis GO:0048546 231 0.036
mitochondrion organization GO:0007005 4 0.036
regulation of establishment of protein localization GO:0070201 4 0.036
Mouse Fly
dorsal ventral pattern formation GO:0009953 125 0.036
single organism nuclear import GO:1902593 3 0.036
Mouse Fly
proteasomal protein catabolic process GO:0010498 2 0.036
Human Mouse
organic substance catabolic process GO:1901575 28 0.036
Human Mouse
cellular nitrogen compound metabolic process GO:0034641 290 0.036
Human Mouse Fly
adult behavior GO:0030534 2 0.036
protein polyubiquitination GO:0000209 4 0.035
Human Mouse
phosphate containing compound metabolic process GO:0006796 108 0.034
Mouse
regulation of meiotic cell cycle GO:0051445 1 0.034
developmental programmed cell death GO:0010623 4 0.033
Fly
negative regulation of metabolic process GO:0009892 86 0.033
Human
organelle organization GO:0006996 227 0.032
Fly
positive regulation of cellular biosynthetic process GO:0031328 68 0.032
Mouse
cellular response to external stimulus GO:0071496 2 0.032
neuron differentiation GO:0030182 353 0.032
Worm Fly
establishment of protein localization to organelle GO:0072594 4 0.032
Mouse Fly
determination of bilateral symmetry GO:0009855 204 0.032
chordate embryonic development GO:0043009 271 0.031
maintenance of location GO:0051235 4 0.031
Fly
positive regulation of macromolecule metabolic process GO:0010604 93 0.031
Human Mouse
macromolecule biosynthetic process GO:0009059 227 0.031
Human Mouse
cell surface receptor signaling pathway GO:0007166 325 0.031
Fly
sleep GO:0030431 1 0.030
heart development GO:0007507 313 0.030
regulation of biological quality GO:0065008 263 0.030
Human Fly
cell cycle g1 s phase transition GO:0044843 1 0.030
regulation of cell shape GO:0008360 1 0.029
embryonic organ development GO:0048568 381 0.029
vasculature development GO:0001944 278 0.029
cellular component biogenesis GO:0044085 178 0.029
Fly
regulation of cell differentiation GO:0045595 142 0.029
Fly
epithelial tube morphogenesis GO:0060562 148 0.029
meiotic nuclear division GO:0007126 4 0.029
cellular protein modification process GO:0006464 100 0.028
Human Mouse Fly
positive regulation of cell cycle GO:0045787 3 0.028
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 4 0.028
embryonic organ morphogenesis GO:0048562 274 0.028
regulation of cellular metabolic process GO:0031323 320 0.027
Human Mouse Fly
protein k48 linked ubiquitination GO:0070936 1 0.027
heart morphogenesis GO:0003007 156 0.027
regulation of nucleocytoplasmic transport GO:0046822 2 0.027
Mouse Fly
positive regulation of cellular process GO:0048522 201 0.027
Human Mouse Fly
developmental growth GO:0048589 166 0.027
regulation of nucleoside metabolic process GO:0009118 2 0.027
cell projection morphogenesis GO:0048858 244 0.027
Worm
g1 s transition of mitotic cell cycle GO:0000082 1 0.027
ameboidal type cell migration GO:0001667 143 0.026
Fly
nucleocytoplasmic transport GO:0006913 4 0.026
Mouse Fly
protein modification process GO:0036211 100 0.026
Human Mouse Fly
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.026
Mouse
regulation of protein targeting GO:1903533 2 0.026
Mouse Fly
regulation of multicellular organismal development GO:2000026 223 0.026
Fly
regulation of synapse assembly GO:0051963 3 0.026
transcription dna templated GO:0006351 181 0.026
Human Mouse
cellular component movement GO:0006928 335 0.025
Fly
sensory organ development GO:0007423 393 0.025
negative regulation of nucleocytoplasmic transport GO:0046823 2 0.025
Mouse Fly
regulation of synapse organization GO:0050807 3 0.025
macromolecule modification GO:0043412 111 0.025
Human Mouse Fly
positive regulation of catabolic process GO:0009896 4 0.025
phosphorylation GO:0016310 69 0.024
organonitrogen compound metabolic process GO:1901564 74 0.024
anterior posterior pattern specification GO:0009952 152 0.024
head development GO:0060322 303 0.024
central nervous system development GO:0007417 387 0.024
negative regulation of response to stimulus GO:0048585 104 0.024
Mouse Fly
gene expression GO:0010467 252 0.024
Human Mouse
transport GO:0006810 220 0.024
Mouse Worm Fly
positive regulation of biosynthetic process GO:0009891 68 0.024
Mouse
macromolecule catabolic process GO:0009057 15 0.024
Human Mouse
response to abiotic stimulus GO:0009628 122 0.024
regulation of intracellular protein transport GO:0033157 3 0.024
Mouse Fly
negative regulation of protein localization to nucleus GO:1900181 2 0.023
Mouse Fly
behavior GO:0007610 74 0.023
Fly
positive regulation of cellular catabolic process GO:0031331 3 0.023
macroautophagy GO:0016236 1 0.023
regulation of protein import into nucleus GO:0042306 2 0.023
Mouse Fly
rna localization GO:0006403 4 0.023
cellular protein metabolic process GO:0044267 129 0.022
Human Mouse Fly
single organism localization GO:1902578 225 0.022
Mouse Fly
negative regulation of cell communication GO:0010648 96 0.022
Mouse Fly
regulation of rna biosynthetic process GO:2001141 213 0.022
Human Mouse
cellular response to stress GO:0033554 62 0.022
regulation of nucleic acid templated transcription GO:1903506 213 0.022
Human Mouse
negative regulation of macromolecule metabolic process GO:0010605 76 0.022
Human
peptidyl serine phosphorylation GO:0018105 1 0.022
protein targeting to nucleus GO:0044744 3 0.022
Mouse Fly
negative regulation of intracellular transport GO:0032387 3 0.022
Mouse Fly
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.021
Human Mouse
protein import into nucleus GO:0006606 3 0.021
Mouse Fly
regulation of response to stimulus GO:0048583 269 0.021
Mouse Fly
peptidyl serine modification GO:0018209 2 0.021
regulation of cell communication GO:0010646 232 0.021
Mouse Fly
regulation of primary metabolic process GO:0080090 311 0.021
Human Mouse Fly
single organism transport GO:0044765 206 0.021
Mouse Fly
response to external stimulus GO:0009605 264 0.021
negative regulation of macromolecule biosynthetic process GO:0010558 48 0.020
Human
growth GO:0040007 174 0.020
regulation of anatomical structure morphogenesis GO:0022603 130 0.020
negative regulation of cellular biosynthetic process GO:0031327 55 0.020
Human
positive regulation of cell adhesion GO:0045785 1 0.020
regulation of cytoplasmic transport GO:1903649 4 0.020
Mouse Fly
positive regulation of metabolic process GO:0009893 108 0.020
Human Mouse
regulation of cell development GO:0060284 100 0.020
Fly
calcium ion transport into cytosol GO:0060402 3 0.020
cellular response to extracellular stimulus GO:0031668 2 0.020
gland development GO:0048732 143 0.020
locomotor rhythm GO:0045475 3 0.020
Fly
regulation of intracellular signal transduction GO:1902531 57 0.019
Mouse Fly
autophagy GO:0006914 4 0.019
modification dependent macromolecule catabolic process GO:0043632 3 0.019
Human Mouse
negative regulation of protein phosphorylation GO:0001933 4 0.019
cell migration GO:0016477 237 0.019
Fly
immune system development GO:0002520 191 0.019
taxis GO:0042330 109 0.019
internal protein amino acid acetylation GO:0006475 2 0.019
response to topologically incorrect protein GO:0035966 2 0.019
nucleobase containing compound biosynthetic process GO:0034654 205 0.019
Human Mouse
cellular response to starvation GO:0009267 1 0.019
negative regulation of cellular metabolic process GO:0031324 77 0.019
Human
cell motility GO:0048870 244 0.019
Fly
negative regulation of protein import into nucleus GO:0042308 2 0.019
Mouse Fly
regulation of microtubule cytoskeleton organization GO:0070507 3 0.019
Fly
sensory perception of chemical stimulus GO:0007606 3 0.019
negative regulation of intracellular protein transport GO:0090317 3 0.019
Mouse Fly
regulation of protein modification by small protein conjugation or removal GO:1903320 3 0.019
regulation of signal transduction GO:0009966 225 0.018
Mouse Fly
cell migration involved in gastrulation GO:0042074 79 0.018
catabolic process GO:0009056 32 0.018
Human Mouse
regulation of cell morphogenesis GO:0022604 42 0.018
organic cyclic compound metabolic process GO:1901360 301 0.018
Human Mouse Fly
guanosine containing compound catabolic process GO:1901069 2 0.018
phosphorus metabolic process GO:0006793 109 0.018
Mouse
regulation of rna metabolic process GO:0051252 224 0.018
Human Mouse
stem cell maintenance GO:0019827 4 0.018
meiotic chromosome segregation GO:0045132 3 0.018
regulation of wnt signaling pathway GO:0030111 53 0.018
Fly
regulation of nucleotide catabolic process GO:0030811 2 0.017
single organism organelle organization GO:1902589 199 0.017
Fly
localization of cell GO:0051674 244 0.017
Fly
rna biosynthetic process GO:0032774 181 0.017
Human Mouse
regulation of protein complex assembly GO:0043254 3 0.017
regulation of circadian rhythm GO:0042752 4 0.017
Mouse
cellular response to organic substance GO:0071310 105 0.017
Fly
positive regulation of macromolecule biosynthetic process GO:0010557 59 0.017
Mouse
immune system process GO:0002376 241 0.017
smoothened signaling pathway GO:0007224 30 0.017
Fly
negative regulation of nitrogen compound metabolic process GO:0051172 59 0.017
Human
cell cycle process GO:0022402 53 0.016
Fly
cell projection organization GO:0030030 284 0.016
Worm
negative regulation of protein transport GO:0051224 3 0.016
Mouse Fly
cellular response to nutrient levels GO:0031669 2 0.016
regulation of cell activation GO:0050865 1 0.016
cellular macromolecule catabolic process GO:0044265 12 0.016
Human Mouse
cellular component assembly involved in morphogenesis GO:0010927 107 0.016
Fly
negative regulation of catabolic process GO:0009895 3 0.016
regulation of transcription dna templated GO:0006355 213 0.016
Human Mouse
determination of left right symmetry GO:0007368 179 0.016
ribonucleoside monophosphate catabolic process GO:0009158 4 0.016
hepaticobiliary system development GO:0061008 98 0.016
protein polymerization GO:0051258 4 0.015
dna templated transcription elongation GO:0006354 3 0.015
single organism membrane fusion GO:0044801 2 0.015
internal peptidyl lysine acetylation GO:0018393 2 0.015
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.015
Human Mouse Fly
mitotic dna damage checkpoint GO:0044773 4 0.015
liver development GO:0001889 96 0.015
cognition GO:0050890 1 0.015
Fly
positive regulation of stress activated protein kinase signaling cascade GO:0070304 3 0.015
regulation of organelle assembly GO:1902115 4 0.015
Fly
response to drug GO:0042493 3 0.015
response to organic substance GO:0010033 153 0.015
Fly
cellular localization GO:0051641 97 0.015
Mouse Fly
purine nucleoside monophosphate catabolic process GO:0009128 4 0.015
regulation of protein ubiquitination GO:0031396 3 0.015
sex determination GO:0007530 1 0.014
positive regulation of map kinase activity GO:0043406 3 0.014
microtubule organizing center organization GO:0031023 1 0.014
Fly
atp catabolic process GO:0006200 4 0.014
cilium assembly GO:0042384 58 0.014
macromolecular complex disassembly GO:0032984 1 0.014
guanosine containing compound metabolic process GO:1901068 4 0.014
activation of mapk activity GO:0000187 3 0.014
positive regulation of chromatin modification GO:1903310 1 0.014
negative regulation of signaling GO:0023057 96 0.014
Mouse Fly
mesenchyme development GO:0060485 127 0.014
cell morphogenesis involved in differentiation GO:0000904 195 0.014
Fly
programmed cell death GO:0012501 119 0.014
Fly
purine ribonucleoside monophosphate catabolic process GO:0009169 4 0.014
peptidyl threonine phosphorylation GO:0018107 1 0.014
g2 dna damage checkpoint GO:0031572 3 0.014
negative regulation of cytoplasmic transport GO:1903650 2 0.014
Mouse Fly
gtp catabolic process GO:0006184 2 0.014
protein acetylation GO:0006473 2 0.014
carboxylic acid metabolic process GO:0019752 22 0.014
protein complex disassembly GO:0043241 1 0.014
apoptotic process involved in development GO:1902742 2 0.014
Fly
stem cell proliferation GO:0072089 4 0.013
primary neural tube formation GO:0014020 1 0.013
protein homooligomerization GO:0051260 3 0.013
organelle assembly GO:0070925 110 0.013
Fly
protein heterooligomerization GO:0051291 1 0.013
regulation of purine nucleotide catabolic process GO:0033121 2 0.013
negative regulation of cell cycle phase transition GO:1901988 5 0.013
cell aging GO:0007569 2 0.013
establishment of localization in cell GO:0051649 77 0.013
Mouse Fly
sequestering of metal ion GO:0051238 3 0.013
actin filament polymerization GO:0030041 2 0.013
cellular protein localization GO:0034613 20 0.013
Mouse Fly
amine metabolic process GO:0009308 2 0.013
regulation of mitotic cell cycle GO:0007346 25 0.013
Fly
vacuolar transport GO:0007034 2 0.013
regulation of cytokine production GO:0001817 3 0.013
positive regulation of signal transduction GO:0009967 56 0.013
Fly
positive regulation of jnk cascade GO:0046330 3 0.013
positive regulation of protein complex assembly GO:0031334 2 0.013
chemotaxis GO:0006935 104 0.013
regulation of embryonic development GO:0045995 47 0.013
regulation of cellular component organization GO:0051128 86 0.013
Fly
blood vessel morphogenesis GO:0048514 216 0.013
gtp metabolic process GO:0046039 4 0.013
membrane fusion GO:0061025 2 0.013
cellular response to dna damage stimulus GO:0006974 24 0.013
regulation of transcription elongation from rna polymerase ii promoter GO:0034243 3 0.013
regulation of dna templated transcription elongation GO:0032784 3 0.013
centrosome organization GO:0051297 1 0.013
Fly
positive regulation of signaling GO:0023056 56 0.013
Fly
mitotic g2 dna damage checkpoint GO:0007095 3 0.012
eye development GO:0001654 277 0.012
positive regulation of cellular metabolic process GO:0031325 94 0.012
Human Mouse
regulation of binding GO:0051098 3 0.012
mitotic g2 m transition checkpoint GO:0044818 3 0.012
neuron projection morphogenesis GO:0048812 161 0.012
Worm
spermatid development GO:0007286 2 0.012
regulation of cellular biosynthetic process GO:0031326 245 0.012
Human Mouse
transcription elongation from rna polymerase ii promoter GO:0006368 3 0.012
release of sequestered calcium ion into cytosol GO:0051209 3 0.012
cellular amine metabolic process GO:0044106 2 0.012
positive regulation of dna metabolic process GO:0051054 1 0.012
response to glucocorticoid GO:0051384 1 0.012
protein localization GO:0008104 40 0.012
Mouse Fly
small gtpase mediated signal transduction GO:0007264 8 0.012
tube closure GO:0060606 1 0.012
blood vessel development GO:0001568 246 0.012
response to monosaccharide GO:0034284 3 0.012
convergent extension involved in organogenesis GO:0060029 10 0.012
response to oxygen levels GO:0070482 25 0.012
negative regulation of cellular macromolecule biosynthetic process GO:2000113 48 0.012
Human
canonical wnt signaling pathway GO:0060070 48 0.012
axon guidance GO:0007411 86 0.012
response to glucose GO:0009749 3 0.012
positive regulation of muscle tissue development GO:1901863 1 0.012
axonogenesis GO:0007409 152 0.012
regulation of mrna splicing via spliceosome GO:0048024 3 0.012
sensory organ morphogenesis GO:0090596 200 0.012
small molecule metabolic process GO:0044281 77 0.012
transcription from rna polymerase ii promoter GO:0006366 80 0.011
cell cycle arrest GO:0007050 1 0.011
regulation of cellular protein catabolic process GO:1903362 1 0.011
negative regulation of biosynthetic process GO:0009890 55 0.011
Human
actin polymerization or depolymerization GO:0008154 2 0.011
peptide transport GO:0015833 1 0.011
Mouse Fly
embryonic heart tube morphogenesis GO:0003143 108 0.011
oocyte anterior posterior axis specification GO:0007314 4 0.011
cellular response to chemical stimulus GO:0070887 157 0.011
Fly
nucleoside monophosphate catabolic process GO:0009125 4 0.011
protein acylation GO:0043543 3 0.011
negative regulation of cell differentiation GO:0045596 46 0.011
Fly
system process GO:0003008 185 0.011
Fly
regulation of smoothened signaling pathway GO:0008589 18 0.011
Fly
peptidyl lysine acetylation GO:0018394 2 0.011
cardiac cell fate commitment GO:0060911 1 0.011
regulation of gtpase activity GO:0043087 2 0.011
positive regulation of cellular component biogenesis GO:0044089 3 0.011
protein modification by small protein conjugation or removal GO:0070647 14 0.011
Human Mouse Fly
nuclear export GO:0051168 1 0.011
positive regulation of developmental process GO:0051094 50 0.011
convergent extension involved in gastrulation GO:0060027 71 0.011
axon development GO:0061564 166 0.010
regulation of cellular amino acid metabolic process GO:0006521 0 0.010
spermatid differentiation GO:0048515 2 0.010
chemosensory behavior GO:0007635 1 0.010
Fly
negative regulation of reproductive process GO:2000242 3 0.010
Fly
septum transversum development GO:0003343 4 0.010
centrosome cycle GO:0007098 1 0.010
Fly
ras protein signal transduction GO:0007265 7 0.010
generation of neurons GO:0048699 385 0.010
Worm Fly
regulation of ras gtpase activity GO:0032318 2 0.010
positive regulation of translation GO:0045727 1 0.010
regulation of gtp catabolic process GO:0033124 2 0.010
actin cytoskeleton organization GO:0030036 63 0.010

fbxw11a disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
cancer DOID:162 0 0.042
disease of cellular proliferation DOID:14566 0 0.042
organ system cancer DOID:0050686 0 0.042
disease of anatomical entity DOID:7 0 0.030
musculoskeletal system disease DOID:17 0 0.016
nervous system disease DOID:863 0 0.013