Danio rerio

67 known processes

fev

FEV (ETS oncogene family)

(Aliases: pet1,zgc:158720)

fev biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
regulation of gene expression GO:0010468 265 0.474
monoamine transport GO:0015844 1 0.310
regulation of cell differentiation GO:0045595 142 0.291
hemopoiesis GO:0030097 183 0.289
blood vessel development GO:0001568 246 0.216
single organism biosynthetic process GO:0044711 71 0.170
sleep GO:0030431 1 0.170
blood vessel morphogenesis GO:0048514 216 0.160
circadian sleep wake cycle GO:0042745 2 0.159
vasculature development GO:0001944 278 0.158
myeloid cell differentiation GO:0030099 86 0.138
intestinal absorption GO:0050892 2 0.127
cellular amine metabolic process GO:0044106 2 0.127
cellular macromolecule biosynthetic process GO:0034645 224 0.123
circadian sleep wake cycle process GO:0022410 2 0.115
sprouting angiogenesis GO:0002040 53 0.111
amine metabolic process GO:0009308 2 0.108
single organism localization GO:1902578 225 0.107
erythrocyte homeostasis GO:0034101 55 0.101
cell substrate adhesion GO:0031589 4 0.095
ion transport GO:0006811 114 0.095
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.093
hypothalamus cell differentiation GO:0021979 4 0.084
organic cyclic compound metabolic process GO:1901360 301 0.082
heterocycle biosynthetic process GO:0018130 215 0.081
stem cell differentiation GO:0048863 117 0.080
catecholamine metabolic process GO:0006584 2 0.080
immune system process GO:0002376 241 0.076
membrane hyperpolarization GO:0060081 1 0.075
catechol containing compound metabolic process GO:0009712 2 0.075
aromatic compound biosynthetic process GO:0019438 217 0.070
lipid catabolic process GO:0016042 4 0.069
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 2 0.067
regulation of cellular biosynthetic process GO:0031326 245 0.066
smooth muscle contraction GO:0006939 2 0.064
organic acid metabolic process GO:0006082 31 0.064
negative regulation of signaling GO:0023057 96 0.060
mononuclear cell proliferation GO:0032943 1 0.060
leukocyte proliferation GO:0070661 1 0.059
columnar cuboidal epithelial cell differentiation GO:0002065 38 0.058
cellular biogenic amine metabolic process GO:0006576 2 0.058
regulation of multicellular organismal development GO:2000026 223 0.056
phagocytosis GO:0006909 3 0.056
regulation of cellular ketone metabolic process GO:0010565 7 0.053
regulation of postsynaptic membrane potential GO:0060078 1 0.053
small molecule metabolic process GO:0044281 77 0.053
iron ion homeostasis GO:0055072 4 0.051
nitrogen compound metabolic process GO:0006807 319 0.051
regulation of primary metabolic process GO:0080090 311 0.051
autophagy GO:0006914 4 0.051
immune system development GO:0002520 191 0.050
xanthophore differentiation GO:0050936 3 0.050
mesenchyme development GO:0060485 127 0.049
heart process GO:0003015 71 0.047
organonitrogen compound biosynthetic process GO:1901566 47 0.047
single organism metabolic process GO:0044710 217 0.047
regulation of metal ion transport GO:0010959 4 0.047
regulation of extrinsic apoptotic signaling pathway in absence of ligand GO:2001239 1 0.046
venous endothelial cell migration involved in lymph vessel development GO:0060855 4 0.046
cellular amino acid metabolic process GO:0006520 7 0.046
cellular nitrogen compound biosynthetic process GO:0044271 218 0.044
cellular response to oxygen levels GO:0071453 1 0.044
macromolecule biosynthetic process GO:0009059 227 0.044
enzyme linked receptor protein signaling pathway GO:0007167 106 0.043
negative regulation of leukocyte differentiation GO:1902106 1 0.043
definitive hemopoiesis GO:0060216 18 0.043
regulation of cell communication GO:0010646 232 0.041
osteoclast differentiation GO:0030316 1 0.041
indole containing compound biosynthetic process GO:0042435 1 0.041
cell differentiation in spinal cord GO:0021515 40 0.041
regulation of protein binding GO:0043393 3 0.040
response to carbohydrate GO:0009743 3 0.040
oxoacid metabolic process GO:0043436 31 0.040
cellular nitrogen compound metabolic process GO:0034641 290 0.040
signal transduction in absence of ligand GO:0038034 1 0.040
response to biotic stimulus GO:0009607 97 0.040
lymphocyte proliferation GO:0046651 1 0.039
regulation of cellular amine metabolic process GO:0033238 0 0.039
response to oxygen levels GO:0070482 25 0.038
serotonin metabolic process GO:0042428 1 0.038
negative regulation of biological process GO:0048519 304 0.038
organic substance biosynthetic process GO:1901576 289 0.038
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 42 0.037
negative regulation of apoptotic process GO:0043066 55 0.037
response to other organism GO:0051707 97 0.037
epithelial cell differentiation GO:0030855 116 0.036
regulation of macromolecule metabolic process GO:0060255 317 0.036
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.036
positive regulation of cell adhesion GO:0045785 1 0.036
cellular response to starvation GO:0009267 1 0.035
negative regulation of extrinsic apoptotic signaling pathway GO:2001237 2 0.035
negative regulation of mapk cascade GO:0043409 4 0.035
regulation of apoptotic process GO:0042981 98 0.034
regulation of response to stimulus GO:0048583 269 0.034
digestive system process GO:0022600 9 0.034
cellular response to extracellular stimulus GO:0031668 2 0.034
macrophage chemotaxis GO:0048246 3 0.033
myeloid cell homeostasis GO:0002262 56 0.033
positive regulation of epithelial cell migration GO:0010634 2 0.033
dopamine metabolic process GO:0042417 2 0.033
endocrine system development GO:0035270 65 0.033
cation transport GO:0006812 81 0.033
pancreatic a cell development GO:0003322 2 0.032
regulation of signaling GO:0023051 235 0.032
tube morphogenesis GO:0035239 349 0.032
dopamine biosynthetic process GO:0042416 2 0.032
rna metabolic process GO:0016070 219 0.032
sensory system development GO:0048880 76 0.031
cellular biosynthetic process GO:0044249 286 0.031
organonitrogen compound metabolic process GO:1901564 74 0.031
angiogenesis GO:0001525 158 0.031
nucleic acid templated transcription GO:0097659 181 0.031
hematopoietic or lymphoid organ development GO:0048534 191 0.031
indole containing compound metabolic process GO:0042430 2 0.030
endocrine process GO:0050886 2 0.030
regulation of cell activation GO:0050865 1 0.030
cellular ketone metabolic process GO:0042180 11 0.030
establishment of localization GO:0051234 244 0.029
signal transduction GO:0007165 455 0.029
positive regulation of cytoskeleton organization GO:0051495 3 0.029
cellular iron ion homeostasis GO:0006879 3 0.029
regulation of multicellular organismal process GO:0051239 277 0.029
homeostasis of number of cells GO:0048872 62 0.028
regulation of circadian sleep wake cycle GO:0042749 1 0.028
alpha amino acid metabolic process GO:1901605 3 0.028
carboxylic acid metabolic process GO:0019752 22 0.027
response to abiotic stimulus GO:0009628 122 0.027
leukocyte differentiation GO:0002521 25 0.027
cellular response to molecule of bacterial origin GO:0071219 3 0.027
aromatic amino acid family metabolic process GO:0009072 1 0.026
optomotor response GO:0071632 1 0.026
embryonic axis specification GO:0000578 12 0.026
positive regulation of cytokine production GO:0001819 2 0.026
multicellular organismal response to stress GO:0033555 2 0.026
regulation of sodium ion transport GO:0002028 2 0.026
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.026
regulation of sequence specific dna binding transcription factor activity GO:0051090 9 0.026
hormone secretion GO:0046879 2 0.026
regulation of rna biosynthetic process GO:2001141 213 0.026
regulation of binding GO:0051098 3 0.025
negative regulation of myeloid cell differentiation GO:0045638 1 0.025
embryonic digestive tract morphogenesis GO:0048557 3 0.025
cell surface receptor signaling pathway GO:0007166 325 0.025
regulation of cell death GO:0010941 103 0.025
transcription from rna polymerase ii promoter GO:0006366 80 0.025
regulation of circadian sleep wake cycle sleep GO:0045187 1 0.025
regulation of cell shape GO:0008360 1 0.025
neuroblast proliferation GO:0007405 2 0.024
neuron neuron synaptic transmission GO:0007270 1 0.024
positive regulation of histone modification GO:0031058 1 0.024
regulation of protein complex assembly GO:0043254 3 0.024
stem cell proliferation GO:0072089 4 0.024
transport GO:0006810 220 0.023
generation of neurons GO:0048699 385 0.023
regulation of developmental process GO:0050793 247 0.023
regulation of programmed cell death GO:0043067 101 0.022
behavior GO:0007610 74 0.022
branching morphogenesis of an epithelial tube GO:0048754 15 0.022
vasculogenesis GO:0001570 41 0.022
carbohydrate homeostasis GO:0033500 1 0.022
type b pancreatic cell development GO:0003323 4 0.022
cardiac chamber formation GO:0003207 4 0.022
negative regulation of cellular process GO:0048523 283 0.022
positive regulation of cellular amine metabolic process GO:0033240 0 0.022
appendage morphogenesis GO:0035107 56 0.022
regulation of cytokine production GO:0001817 3 0.022
eye morphogenesis GO:0048592 144 0.022
meiotic nuclear division GO:0007126 4 0.022
osteoclast development GO:0036035 1 0.022
catecholamine biosynthetic process GO:0042423 2 0.021
circadian sleep wake cycle sleep GO:0050802 1 0.021
lipid storage GO:0019915 1 0.021
lateral line development GO:0048882 66 0.021
granulocyte chemotaxis GO:0071621 11 0.021
regulation of biological quality GO:0065008 263 0.021
cellular transition metal ion homeostasis GO:0046916 3 0.021
negative regulation of nitrogen compound metabolic process GO:0051172 59 0.020
pigmentation GO:0043473 85 0.020
granulocyte migration GO:0097530 11 0.020
cellular response to nutrient levels GO:0031669 2 0.020
regulation of fatty acid metabolic process GO:0019217 1 0.020
nucleic acid metabolic process GO:0090304 244 0.020
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 4 0.020
cellular response to reactive oxygen species GO:0034614 2 0.019
cell matrix adhesion GO:0007160 4 0.019
spinal cord development GO:0021510 46 0.019
hormone transport GO:0009914 2 0.019
negative regulation of multicellular organismal process GO:0051241 69 0.019
organic cyclic compound biosynthetic process GO:1901362 223 0.019
primary amino compound metabolic process GO:1901160 1 0.019
regulation of biosynthetic process GO:0009889 250 0.019
regulation of nitrogen compound metabolic process GO:0051171 251 0.019
leukocyte migration GO:0050900 15 0.019
gas transport GO:0015669 3 0.019
negative regulation of cell death GO:0060548 60 0.019
cellular response to external stimulus GO:0071496 2 0.018
cell proliferation GO:0008283 80 0.018
positive regulation of gliogenesis GO:0014015 2 0.018
aorta development GO:0035904 4 0.018
positive regulation of positive chemotaxis GO:0050927 4 0.018
regulation of circadian rhythm GO:0042752 4 0.018
protein heterooligomerization GO:0051291 1 0.018
apoptotic signaling pathway GO:0097190 23 0.018
negative regulation of heart contraction GO:0045822 2 0.018
myeloid leukocyte differentiation GO:0002573 15 0.018
positive regulation of chromatin modification GO:1903310 1 0.018
cellular macromolecule metabolic process GO:0044260 391 0.018
maintenance of location GO:0051235 4 0.018
regulation of reproductive process GO:2000241 4 0.018
hypothalamus development GO:0021854 14 0.018
regulation of cellular amino acid metabolic process GO:0006521 0 0.017
epithelial cell morphogenesis GO:0003382 2 0.017
ion transmembrane transport GO:0034220 91 0.017
positive regulation of cellular component biogenesis GO:0044089 3 0.017
regulation of cellular component organization GO:0051128 86 0.017
regulation of extrinsic apoptotic signaling pathway GO:2001236 3 0.017
macroautophagy GO:0016236 1 0.017
sequestering of metal ion GO:0051238 3 0.017
respiratory burst GO:0045730 2 0.017
negative regulation of signal transduction in absence of ligand GO:1901099 1 0.017
positive regulation of cell activation GO:0050867 1 0.017
nitric oxide metabolic process GO:0046209 2 0.017
nephron epithelium morphogenesis GO:0072088 1 0.017
positive regulation of lipid metabolic process GO:0045834 1 0.017
positive regulation of cell matrix adhesion GO:0001954 1 0.017
positive regulation of immune system process GO:0002684 17 0.017
negative regulation of protein serine threonine kinase activity GO:0071901 2 0.017
appendage development GO:0048736 80 0.017
negative regulation of programmed cell death GO:0043069 58 0.017
organic acid catabolic process GO:0016054 3 0.016
myeloid leukocyte migration GO:0097529 12 0.016
sequestering of calcium ion GO:0051208 3 0.016
embryonic skeletal system development GO:0048706 97 0.016
enteric nervous system development GO:0048484 12 0.016
adherens junction organization GO:0034332 4 0.016
renal tubule morphogenesis GO:0061333 1 0.016
cellular response to lipopolysaccharide GO:0071222 3 0.016
neutral amino acid transport GO:0015804 2 0.016
regulation of autophagy GO:0010506 3 0.015
protein metabolic process GO:0019538 183 0.015
gland development GO:0048732 143 0.015
peptide metabolic process GO:0006518 1 0.015
leukocyte chemotaxis GO:0030595 12 0.015
erk1 and erk2 cascade GO:0070371 4 0.015
peptidyl lysine acetylation GO:0018394 2 0.015
response to estrogen GO:0043627 27 0.015
stem cell fate commitment GO:0048865 1 0.015
negative regulation of protein kinase activity GO:0006469 4 0.015
epithelial cell development GO:0002064 42 0.015
olfactory bulb development GO:0021772 4 0.015
cytoskeleton organization GO:0007010 96 0.014
neutrophil migration GO:1990266 10 0.014
regulation of tissue remodeling GO:0034103 2 0.014
regulation of molecular function GO:0065009 70 0.014
gastrulation GO:0007369 208 0.014
negative regulation of blood circulation GO:1903523 2 0.014
extrinsic apoptotic signaling pathway GO:0097191 3 0.014
membrane raft organization GO:0031579 1 0.014
regulation of organ growth GO:0046620 3 0.014
immunoglobulin mediated immune response GO:0016064 3 0.014
fin development GO:0033333 77 0.014
positive regulation of cell substrate adhesion GO:0010811 1 0.014
respiratory system development GO:0060541 5 0.014
positive regulation of protein complex assembly GO:0031334 2 0.014
negative regulation of macromolecule metabolic process GO:0010605 76 0.014
regulation of glucose import GO:0046324 1 0.014
regulation of hematopoietic progenitor cell differentiation GO:1901532 1 0.014
stem cell maintenance GO:0019827 4 0.014
neuroepithelial cell differentiation GO:0060563 26 0.014
single organism transport GO:0044765 206 0.014
regulation of phosphorus metabolic process GO:0051174 43 0.014
nephron morphogenesis GO:0072028 2 0.014
programmed cell death GO:0012501 119 0.013
positive regulation of transport GO:0051050 2 0.013
epithelial tube morphogenesis GO:0060562 148 0.013
neurotransmitter transport GO:0006836 2 0.013
response to hypoxia GO:0001666 25 0.013
nephron tubule morphogenesis GO:0072078 1 0.013
central nervous system myelin formation GO:0032289 1 0.013
canonical wnt signaling pathway involved in neural plate anterior posterior pattern formation GO:0060823 4 0.013
primitive hemopoiesis GO:0060215 27 0.013
catechol containing compound biosynthetic process GO:0009713 2 0.013
determination of heart left right asymmetry GO:0061371 117 0.013
positive regulation of cellular catabolic process GO:0031331 3 0.013
embryonic digestive tract development GO:0048566 4 0.013
positive regulation of stress activated mapk cascade GO:0032874 3 0.013
negative regulation of kinase activity GO:0033673 4 0.013
regulation of metabolic process GO:0019222 359 0.013
positive regulation of catabolic process GO:0009896 4 0.013
positive regulation of translation GO:0045727 1 0.013
organ formation GO:0048645 17 0.013
glucose import GO:0046323 2 0.013
negative regulation of metabolic process GO:0009892 86 0.013
regulation of transcription from rna polymerase ii promoter GO:0006357 114 0.013
positive regulation of gene expression GO:0010628 71 0.013
cardiac atrium morphogenesis GO:0003209 2 0.013
negative regulation of extrinsic apoptotic signaling pathway in absence of ligand GO:2001240 1 0.013
aorta morphogenesis GO:0035909 3 0.013
synaptic transmission glycinergic GO:0060012 1 0.013
single organism behavior GO:0044708 24 0.013
sex determination GO:0007530 1 0.013
organic hydroxy compound transport GO:0015850 14 0.013
negative regulation of cell communication GO:0010648 96 0.013
lymphoid lineage cell migration into thymus GO:0097535 4 0.013
eye development GO:0001654 277 0.013
positive regulation of macrophage chemotaxis GO:0010759 1 0.013
posterior lateral line development GO:0048916 38 0.013
muscle fiber development GO:0048747 52 0.013
regulation of neuron migration GO:2001222 2 0.012
negative regulation of apoptotic signaling pathway GO:2001234 10 0.012
neuronal stem cell maintenance GO:0097150 2 0.012
glucose homeostasis GO:0042593 1 0.012
regulation of mrna processing GO:0050684 3 0.012
meiotic cell cycle process GO:1903046 3 0.012
serotonin transport GO:0006837 1 0.012
production of molecular mediator of immune response GO:0002440 2 0.012
anion transmembrane transport GO:0098656 12 0.012
dorsal motor nucleus of vagus nerve development GO:0021744 4 0.012
positive regulation of erk1 and erk2 cascade GO:0070374 2 0.012
neural crest cell development GO:0014032 62 0.012
axon ensheathment in central nervous system GO:0032291 2 0.012
adrenal gland development GO:0030325 10 0.012
positive regulation of neuron migration GO:2001224 2 0.012
regulation of localization GO:0032879 104 0.012
response to external biotic stimulus GO:0043207 97 0.012
single organism organelle organization GO:1902589 199 0.012
cytosolic calcium ion transport GO:0060401 3 0.012
myeloid cell development GO:0061515 32 0.012
macrophage differentiation GO:0030225 7 0.012
regulation of cellular carbohydrate metabolic process GO:0010675 4 0.012
venous blood vessel development GO:0060841 9 0.012
positive regulation of tyrosine phosphorylation of stat3 protein GO:0042517 1 0.012
regulation of tyrosine phosphorylation of stat protein GO:0042509 1 0.012
membrane fusion GO:0061025 2 0.012
response to organic substance GO:0010033 153 0.012
cellular cation homeostasis GO:0030003 17 0.012
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.012
extrinsic apoptotic signaling pathway in absence of ligand GO:0097192 1 0.011
peptide transport GO:0015833 1 0.011
heart contraction GO:0060047 71 0.011
spindle assembly GO:0051225 2 0.011
cell substrate junction assembly GO:0007044 2 0.011
regulation of cell migration involved in sprouting angiogenesis GO:0090049 3 0.011
positive regulation of leukocyte migration GO:0002687 2 0.011
regulation of macromolecule biosynthetic process GO:0010556 225 0.011
regulation of reactive oxygen species metabolic process GO:2000377 2 0.011
regulation of endothelial cell proliferation GO:0001936 1 0.011
positive regulation of peptidyl tyrosine phosphorylation GO:0050731 1 0.011
regulation of response to biotic stimulus GO:0002831 2 0.011
megakaryocyte differentiation GO:0030219 1 0.011
cation transmembrane transport GO:0098655 65 0.011
internal peptidyl lysine acetylation GO:0018393 2 0.011
homeostatic process GO:0042592 142 0.011
tissue remodeling GO:0048771 4 0.011
amino acid transport GO:0006865 2 0.011
positive chemotaxis GO:0050918 5 0.011
rna biosynthetic process GO:0032774 181 0.011
negative regulation of catalytic activity GO:0043086 21 0.011
regulation of muscle contraction GO:0006937 3 0.011
positive regulation of immune effector process GO:0002699 3 0.011
spinal cord motor neuron differentiation GO:0021522 26 0.011
regulation of glucose transport GO:0010827 1 0.011
digestive system development GO:0055123 289 0.011
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.011
lateral inhibition GO:0046331 1 0.011
positive regulation of protein polymerization GO:0032273 2 0.011
interspecies interaction between organisms GO:0044419 4 0.011
regulation of calcium ion transport GO:0051924 2 0.010
i kappab kinase nf kappab signaling GO:0007249 4 0.010
heterocycle metabolic process GO:0046483 290 0.010
pectoral fin development GO:0033339 50 0.010
cellular response to biotic stimulus GO:0071216 3 0.010
modification dependent macromolecule catabolic process GO:0043632 3 0.010
ventral spinal cord development GO:0021517 35 0.010
neutrophil chemotaxis GO:0030593 10 0.010
protein acetylation GO:0006473 2 0.010
response to hydrogen peroxide GO:0042542 3 0.010
segment polarity determination GO:0007367 1 0.010
response to glucose GO:0009749 3 0.010
negative regulation of secretion by cell GO:1903531 2 0.010

fev disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
organ system cancer DOID:0050686 0 0.033
disease of cellular proliferation DOID:14566 0 0.033
cancer DOID:162 0 0.033
disease of metabolism DOID:0014667 0 0.012