Danio rerio

22 known processes

fga

fibrinogen alpha chain

(Aliases: zgc:92117,wu:fb20e08,wu:fb59b03,sb:cb892,wu:fa55c12,wu:fi39d04)

fga biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
hemostasis GO:0007599 13 0.475
blood coagulation fibrin clot formation GO:0072378 3 0.433
cellular macromolecule metabolic process GO:0044260 391 0.370
regulation of cellular metabolic process GO:0031323 320 0.344
Human
response to stress GO:0006950 263 0.208
blood coagulation GO:0007596 12 0.201
protein metabolic process GO:0019538 183 0.161
negative regulation of cellular process GO:0048523 283 0.160
Human
cellular response to chemical stimulus GO:0070887 157 0.155
regulation of biological quality GO:0065008 263 0.153
coagulation GO:0050817 13 0.149
regulation of metabolic process GO:0019222 359 0.137
Human
cellular response to estrogen stimulus GO:0071391 24 0.133
regulation of wound healing GO:0061041 2 0.115
macromolecule biosynthetic process GO:0009059 227 0.115
regulation of macromolecule metabolic process GO:0060255 317 0.111
transcription dna templated GO:0006351 181 0.102
positive regulation of biological process GO:0048518 253 0.095
Human
blood vessel development GO:0001568 246 0.093
cell matrix adhesion GO:0007160 4 0.087
Human
wound healing GO:0042060 90 0.087
regulation of response to stimulus GO:0048583 269 0.085
Human
regulation of cell substrate adhesion GO:0010810 1 0.080
negative regulation of endopeptidase activity GO:0010951 10 0.080
aging GO:0007568 2 0.079
single organism metabolic process GO:0044710 217 0.077
organic cyclic compound biosynthetic process GO:1901362 223 0.076
gene expression GO:0010467 252 0.072
cell substrate adhesion GO:0031589 4 0.071
Human
regulation of biosynthetic process GO:0009889 250 0.070
biosynthetic process GO:0009058 294 0.070
growth GO:0040007 174 0.068
Rat
regulation of gene expression GO:0010468 265 0.066
cell motility GO:0048870 244 0.065
cellular macromolecule biosynthetic process GO:0034645 224 0.063
cellular component movement GO:0006928 335 0.061
positive regulation of cellular process GO:0048522 201 0.059
Human
cell migration GO:0016477 237 0.059
cellular biosynthetic process GO:0044249 286 0.056
negative regulation of biological process GO:0048519 304 0.055
Human
tube morphogenesis GO:0035239 349 0.055
negative regulation of cell adhesion GO:0007162 6 0.054
organic substance biosynthetic process GO:1901576 289 0.054
signal transduction GO:0007165 455 0.053
Human
central nervous system development GO:0007417 387 0.052
localization of cell GO:0051674 244 0.050
response to chemical GO:0042221 320 0.049
Human
blood vessel morphogenesis GO:0048514 216 0.048
response to wounding GO:0009611 116 0.048
morphogenesis of an epithelium GO:0002009 333 0.048
regulation of primary metabolic process GO:0080090 311 0.044
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.044
cellular protein catabolic process GO:0044257 4 0.043
multicellular organism growth GO:0035264 4 0.043
nucleic acid metabolic process GO:0090304 244 0.042
gastrulation GO:0007369 208 0.042
cellular response to lipid GO:0071396 39 0.042
regulation of nitrogen compound metabolic process GO:0051171 251 0.042
muscle structure development GO:0061061 196 0.041
regulation of cytokine production GO:0001817 3 0.041
regulation of hemostasis GO:1900046 1 0.039
cellular protein metabolic process GO:0044267 129 0.039
immune system process GO:0002376 241 0.038
rna metabolic process GO:0016070 219 0.038
organic cyclic compound metabolic process GO:1901360 301 0.036
neuron differentiation GO:0030182 353 0.035
positive regulation of wound healing GO:0090303 1 0.034
heterocycle metabolic process GO:0046483 290 0.034
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.034
brain development GO:0007420 293 0.033
cellular amino acid metabolic process GO:0006520 7 0.033
vasculature development GO:0001944 278 0.033
positive regulation of cell substrate adhesion GO:0010811 1 0.032
nucleic acid templated transcription GO:0097659 181 0.032
peptidyl serine phosphorylation GO:0018105 1 0.032
carboxylic acid metabolic process GO:0019752 22 0.032
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.032
cellular response to external stimulus GO:0071496 2 0.031
extracellular matrix organization GO:0030198 27 0.031
astrocyte differentiation GO:0048708 1 0.031
regulation of multicellular organismal process GO:0051239 277 0.031
Human
negative regulation of protein processing GO:0010955 10 0.029
positive regulation of cellular amine metabolic process GO:0033240 0 0.029
negative regulation of macromolecule metabolic process GO:0010605 76 0.029
single organism localization GO:1902578 225 0.029
Human
negative regulation of metabolic process GO:0009892 86 0.029
embryonic organ morphogenesis GO:0048562 274 0.028
inner ear development GO:0048839 126 0.027
cellular protein modification process GO:0006464 100 0.027
regulation of rna metabolic process GO:0051252 224 0.027
locomotion GO:0040011 313 0.027
extracellular structure organization GO:0043062 27 0.026
cellular amine metabolic process GO:0044106 2 0.026
generation of neurons GO:0048699 385 0.026
regulation of cellular amine metabolic process GO:0033238 0 0.026
lipid storage GO:0019915 1 0.026
rna biosynthetic process GO:0032774 181 0.026
heart development GO:0007507 313 0.026
response to organic cyclic compound GO:0014070 51 0.026
cell surface receptor signaling pathway GO:0007166 325 0.026
Human
central nervous system neuron differentiation GO:0021953 74 0.025
peptide metabolic process GO:0006518 1 0.025
muscle cell differentiation GO:0042692 139 0.025
regulation of anatomical structure morphogenesis GO:0022603 130 0.024
regulation of rna biosynthetic process GO:2001141 213 0.024
angiogenesis GO:0001525 158 0.024
response to steroid hormone GO:0048545 35 0.023
positive regulation of cell adhesion GO:0045785 1 0.023
Human
homeostatic process GO:0042592 142 0.023
transport GO:0006810 220 0.023
Human
neuron death GO:0070997 21 0.023
regulation of protein processing GO:0070613 10 0.023
determination of heart left right asymmetry GO:0061371 117 0.023
female sex differentiation GO:0046660 4 0.023
regulation of extrinsic apoptotic signaling pathway GO:2001236 3 0.022
Human
regulation of cellular biosynthetic process GO:0031326 245 0.022
meiotic nuclear division GO:0007126 4 0.022
regulation of developmental process GO:0050793 247 0.022
response to organic substance GO:0010033 153 0.022
cellular nitrogen compound metabolic process GO:0034641 290 0.021
embryonic heart tube morphogenesis GO:0003143 108 0.021
small molecule metabolic process GO:0044281 77 0.021
regulation of multicellular organism growth GO:0040014 4 0.020
epithelial tube morphogenesis GO:0060562 148 0.020
macromolecule modification GO:0043412 111 0.020
maintenance of location GO:0051235 4 0.020
cell adhesion GO:0007155 40 0.020
Human
single organism transport GO:0044765 206 0.020
Human
phosphorus metabolic process GO:0006793 109 0.020
Human
positive regulation of transport GO:0051050 2 0.020
Human
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.020
developmental growth GO:0048589 166 0.020
Rat
fatty acid transport GO:0015908 1 0.019
regulation of macromolecule biosynthetic process GO:0010556 225 0.019
lipoprotein catabolic process GO:0042159 1 0.019
regulation of blood vessel size GO:0050880 2 0.019
Human
cellular response to organic substance GO:0071310 105 0.019
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.019
protein activation cascade GO:0072376 6 0.019
regulation of cellular protein metabolic process GO:0032268 52 0.019
muscle tissue development GO:0060537 110 0.019
protein modification process GO:0036211 100 0.019
protein import into nucleus GO:0006606 3 0.018
intracellular signal transduction GO:0035556 85 0.018
Human
negative regulation of multicellular organismal process GO:0051241 69 0.018
response to external stimulus GO:0009605 264 0.018
regulation of establishment of protein localization GO:0070201 4 0.018
Human
cellular nitrogen compound biosynthetic process GO:0044271 218 0.018
digestive system development GO:0055123 289 0.018
regulation of organ growth GO:0046620 3 0.018
response to estrogen GO:0043627 27 0.018
cellular component disassembly GO:0022411 1 0.017
regulation of blood coagulation GO:0030193 1 0.017
regulation of cellular amino acid metabolic process GO:0006521 0 0.017
oxoacid metabolic process GO:0043436 31 0.017
phosphatidylinositol 3 kinase signaling GO:0014065 2 0.017
system process GO:0003008 185 0.017
Human
determination of left right symmetry GO:0007368 179 0.017
negative regulation of gene expression GO:0010629 65 0.017
regulation of protein metabolic process GO:0051246 56 0.016
response to lipid GO:0033993 60 0.016
regulation of autophagy GO:0010506 3 0.016
response to hormone GO:0009725 48 0.016
proteolysis GO:0006508 38 0.016
transcription from rna polymerase ii promoter GO:0006366 80 0.016
intestinal cholesterol absorption GO:0030299 2 0.016
heterocycle biosynthetic process GO:0018130 215 0.016
regulation of signal transduction GO:0009966 225 0.016
Human
positive regulation of cellular component biogenesis GO:0044089 3 0.016
biological adhesion GO:0022610 40 0.016
Human
cerebellar granular layer morphogenesis GO:0021683 3 0.016
cardiac muscle tissue development GO:0048738 48 0.015
glucocorticoid metabolic process GO:0008211 2 0.015
amine metabolic process GO:0009308 2 0.015
nitrogen compound metabolic process GO:0006807 319 0.015
regulation of protein transport GO:0051223 3 0.015
Human
regulation of transcription dna templated GO:0006355 213 0.015
cellular response to steroid hormone stimulus GO:0071383 31 0.015
regulation of cell proliferation GO:0042127 37 0.015
regeneration GO:0031099 91 0.015
Rat
autophagy GO:0006914 4 0.015
positive regulation of metabolic process GO:0009893 108 0.014
Human
epidermal cell fate specification GO:0009957 4 0.014
regulation of dna replication GO:0006275 3 0.014
fatty acid biosynthetic process GO:0006633 4 0.014
regulation of nucleic acid templated transcription GO:1903506 213 0.014
muscle organ development GO:0007517 101 0.014
establishment of localization GO:0051234 244 0.014
Human
cellular aromatic compound metabolic process GO:0006725 295 0.014
negative regulation of protein maturation GO:1903318 10 0.014
embryo development ending in birth or egg hatching GO:0009792 271 0.014
catabolic process GO:0009056 32 0.014
regulation of protein complex assembly GO:0043254 3 0.014
aromatic compound biosynthetic process GO:0019438 217 0.013
ovulation cycle process GO:0022602 2 0.013
peristalsis GO:0030432 1 0.013
regulation of inflammatory response GO:0050727 2 0.013
larval development GO:0002164 2 0.013
cell morphogenesis GO:0000902 289 0.013
positive regulation of macromolecule metabolic process GO:0010604 93 0.013
hepaticobiliary system development GO:0061008 98 0.013
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.012
neuron development GO:0048666 262 0.012
response to alkaloid GO:0043279 2 0.012
epiboly GO:0090504 41 0.012
b cell activation GO:0042113 2 0.012
digestive tract morphogenesis GO:0048546 231 0.012
extrinsic apoptotic signaling pathway GO:0097191 3 0.012
Human
negative regulation of dna metabolic process GO:0051053 4 0.012
regulation of cell communication GO:0010646 232 0.012
Human
regulation of tyrosine phosphorylation of stat protein GO:0042509 1 0.012
immunoglobulin mediated immune response GO:0016064 3 0.012
cellular ketone metabolic process GO:0042180 11 0.012
hindbrain development GO:0030902 91 0.011
muscle cell development GO:0055001 115 0.011
interspecies interaction between organisms GO:0044419 4 0.011
determination of bilateral symmetry GO:0009855 204 0.011
organic acid metabolic process GO:0006082 31 0.011
regulation of jak stat cascade GO:0046425 3 0.011
cellular lipid catabolic process GO:0044242 3 0.011
positive regulation of transcription dna templated GO:0045893 57 0.011
defense response GO:0006952 47 0.011
nephron tubule morphogenesis GO:0072078 1 0.011
b cell differentiation GO:0030183 1 0.011
response to other organism GO:0051707 97 0.011
nucleobase containing compound biosynthetic process GO:0034654 205 0.011
regulation of endopeptidase activity GO:0052548 23 0.011
apoptotic process GO:0006915 116 0.011
Human
biomineral tissue development GO:0031214 13 0.011
negative regulation of dna replication GO:0008156 2 0.011
nucleobase containing compound metabolic process GO:0006139 274 0.011
female gonad development GO:0008585 4 0.011
heart morphogenesis GO:0003007 156 0.011
regulation of cell shape GO:0008360 1 0.011
spermatid differentiation GO:0048515 2 0.011
ubiquitin dependent protein catabolic process GO:0006511 3 0.011
regulation of localization GO:0032879 104 0.011
Human
positive regulation of cellular metabolic process GO:0031325 94 0.011
Human
cell part morphogenesis GO:0032990 246 0.010
positive regulation of catabolic process GO:0009896 4 0.010
positive regulation of cell death GO:0010942 29 0.010
epiboly involved in gastrulation with mouth forming second GO:0055113 35 0.010
phagocytosis GO:0006909 3 0.010
anatomical structure homeostasis GO:0060249 36 0.010
positive regulation of jak stat cascade GO:0046427 2 0.010
tissue regeneration GO:0042246 74 0.010
Rat
cellular response to nutrient levels GO:0031669 2 0.010
nuclear division GO:0000280 23 0.010
protein phosphorylation GO:0006468 47 0.010
cerebellar granular layer development GO:0021681 3 0.010
cytosolic calcium ion transport GO:0060401 3 0.010
striated muscle tissue development GO:0014706 110 0.010

fga disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.058
Human
cardiovascular system disease DOID:1287 0 0.027
immune system disease DOID:2914 0 0.017
Human
bone marrow disease DOID:4961 0 0.011
hematopoietic system disease DOID:74 0 0.011
Human