Danio rerio

234 known processes

fgf8a

fibroblast growth factor 8 a

(Aliases: ace,id:ibd5031,wu:fb73a06,fgf-8,cb110,fgf8,etID309886.13,MGC101652)

fgf8a biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
sensory organ morphogenesis GO:0090596 200 1.000
specification of symmetry GO:0009799 204 1.000
embryonic organ development GO:0048568 381 1.000
heart morphogenesis GO:0003007 156 0.999
positive regulation of epithelial cell differentiation GO:0030858 2 0.999
positive regulation of skeletal muscle tissue development GO:0048643 1 0.999
appendage development GO:0048736 80 0.999
Zebrafish Mouse
embryonic pectoral fin morphogenesis GO:0035118 24 0.999
Zebrafish
pectoral fin morphogenesis GO:0035138 29 0.999
Zebrafish
cerebellum formation GO:0021588 2 0.999
pituitary gland development GO:0021983 16 0.998
Mouse
determination of heart left right asymmetry GO:0061371 117 0.997
Mouse
determination of left right symmetry GO:0007368 179 0.997
rhombomere development GO:0021546 19 0.994
diencephalon development GO:0021536 58 0.994
Mouse
pancreas development GO:0031016 84 0.994
Zebrafish
regulation of epithelial cell proliferation GO:0050678 3 0.994
inner ear development GO:0048839 126 0.993
enzyme linked receptor protein signaling pathway GO:0007167 106 0.993
Mouse
brain development GO:0007420 293 0.993
forebrain dorsal ventral pattern formation GO:0021798 1 0.992
Mouse
hindbrain morphogenesis GO:0021575 22 0.991
odontogenesis of dentin containing tooth GO:0042475 1 0.989
Mouse
digestive tract development GO:0048565 265 0.989
appendage morphogenesis GO:0035107 56 0.989
Zebrafish Mouse
positive regulation of oligodendrocyte differentiation GO:0048714 1 0.988
regulation of signaling GO:0023051 235 0.987
endocardial cushion morphogenesis GO:0003203 3 0.987
Mouse
forebrain regionalization GO:0021871 4 0.984
Mouse
regulation of signal transduction GO:0009966 225 0.984
camera type eye development GO:0043010 222 0.981
cardioblast differentiation GO:0010002 9 0.981
regulation of multicellular organismal development GO:2000026 223 0.979
heart development GO:0007507 313 0.976
regeneration GO:0031099 91 0.975
forebrain development GO:0030900 96 0.973
Mouse
ectodermal placode morphogenesis GO:0071697 32 0.973
cell migration GO:0016477 237 0.971
ear morphogenesis GO:0042471 64 0.970
negative regulation of biological process GO:0048519 304 0.967
cardiac muscle tissue development GO:0048738 48 0.966
otic vesicle development GO:0071599 42 0.965
endocrine system development GO:0035270 65 0.965
digestive tract morphogenesis GO:0048546 231 0.963
gliogenesis GO:0042063 45 0.960
dorsal ventral neural tube patterning GO:0021904 1 0.959
embryonic skeletal system development GO:0048706 97 0.959
cerebellum morphogenesis GO:0021587 10 0.959
fin morphogenesis GO:0033334 53 0.956
Zebrafish
regulation of eye photoreceptor cell development GO:0042478 2 0.955
sensory organ development GO:0007423 393 0.955
cell migration involved in mesendoderm migration GO:0090134 2 0.951
Mouse
segment polarity determination GO:0007367 1 0.949
ectodermal placode development GO:0071696 37 0.949
larval development GO:0002164 2 0.949
regulation of cell differentiation GO:0045595 142 0.949
pectoral fin development GO:0033339 50 0.948
Zebrafish
mesoderm development GO:0007498 88 0.946
cellular response to organic substance GO:0071310 105 0.943
Mouse
embryonic heart tube development GO:0035050 133 0.943
camera type eye morphogenesis GO:0048593 108 0.942
proepicardium development GO:0003342 4 0.942
cellular biosynthetic process GO:0044249 286 0.941
Mouse
hair cell differentiation GO:0035315 32 0.940
determination of bilateral symmetry GO:0009855 204 0.939
cell surface receptor signaling pathway GO:0007166 325 0.938
astrocyte differentiation GO:0048708 1 0.934
skeletal system development GO:0001501 181 0.931
chordate embryonic development GO:0043009 271 0.928
embryonic digestive tract morphogenesis GO:0048557 3 0.927
ectodermal placode formation GO:0060788 26 0.926
endocardium development GO:0003157 9 0.925
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.922
retina morphogenesis in camera type eye GO:0060042 79 0.920
cell morphogenesis involved in differentiation GO:0000904 195 0.920
Mouse
hematopoietic or lymphoid organ development GO:0048534 191 0.919
central nervous system development GO:0007417 387 0.919
oligodendrocyte differentiation GO:0048709 23 0.918
positive regulation of muscle organ development GO:0048636 1 0.917
neuron fate specification GO:0048665 20 0.907
regulation of anatomical structure morphogenesis GO:0022603 130 0.907
negative regulation of programmed cell death GO:0043069 58 0.907
Mouse
regulation of neuron differentiation GO:0045664 56 0.906
axis elongation involved in somitogenesis GO:0090245 2 0.905
otic vesicle morphogenesis GO:0071600 34 0.902
nucleobase containing compound biosynthetic process GO:0034654 205 0.899
Mouse
embryonic organ morphogenesis GO:0048562 274 0.894
regulation of response to stimulus GO:0048583 269 0.892
auditory receptor cell fate commitment GO:0009912 4 0.891
heart field specification GO:0003128 1 0.890
photoreceptor cell fate specification GO:0043704 1 0.888
gland development GO:0048732 143 0.886
auditory receptor cell differentiation GO:0042491 15 0.886
diencephalon morphogenesis GO:0048852 5 0.882
adenohypophysis development GO:0021984 15 0.881
Mouse
regulation of apoptotic process GO:0042981 98 0.879
Mouse
cellular component morphogenesis GO:0032989 336 0.878
morphogenesis of an epithelium GO:0002009 333 0.877
heart looping GO:0001947 94 0.873
Mouse
eye development GO:0001654 277 0.873
oligodendrocyte cell fate specification GO:0021778 4 0.871
otic vesicle formation GO:0030916 27 0.869
mononuclear cell proliferation GO:0032943 1 0.869
otic placode formation GO:0043049 23 0.866
positive regulation of gene expression GO:0010628 71 0.865
Mouse
axial mesoderm formation GO:0048320 4 0.865
ear development GO:0043583 127 0.865
cell projection organization GO:0030030 284 0.864
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 68 0.861
Mouse
anatomical structure arrangement GO:0048532 2 0.861
cell cell adhesion involved in mesendodermal cell migration GO:0003370 1 0.858
heart valve formation GO:0003188 4 0.856
cerebellum development GO:0021549 17 0.856
somitogenesis GO:0001756 87 0.855
transcription from rna polymerase ii promoter GO:0006366 80 0.852
Mouse
embryonic viscerocranium morphogenesis GO:0048703 52 0.851
photoreceptor cell fate commitment GO:0046552 1 0.851
limb bud formation GO:0060174 2 0.847
Zebrafish
neural tube development GO:0021915 62 0.839
regulation of cell communication GO:0010646 232 0.835
eye morphogenesis GO:0048592 144 0.828
floor plate formation GO:0021508 12 0.824
neural tube patterning GO:0021532 33 0.821
mesodermal cell differentiation GO:0048333 21 0.819
cell morphogenesis GO:0000902 289 0.815
regulation of oligodendrocyte differentiation GO:0048713 1 0.811
nucleic acid templated transcription GO:0097659 181 0.810
Mouse
endocardial cushion formation GO:0003272 2 0.810
Mouse
cellular protein modification process GO:0006464 100 0.808
regulation of gene expression GO:0010468 265 0.808
Mouse
positive regulation of muscle tissue development GO:1901863 1 0.807
neuron projection morphogenesis GO:0048812 161 0.804
regulation of cardiac muscle tissue development GO:0055024 1 0.799
cellular macromolecule biosynthetic process GO:0034645 224 0.793
Mouse
cellular response to endogenous stimulus GO:0071495 68 0.793
Mouse
vestibular reflex GO:0060005 2 0.781
eye photoreceptor cell development GO:0042462 30 0.778
regulation of multicellular organismal process GO:0051239 277 0.777
apoptotic process GO:0006915 116 0.777
Mouse
kupffer s vesicle development GO:0070121 50 0.776
endodermal digestive tract morphogenesis GO:0061031 2 0.772
cellular response to growth factor stimulus GO:0071363 39 0.770
Mouse
endocardium formation GO:0060214 1 0.763
lateral mesoderm development GO:0048368 23 0.763
cardioblast migration to the midline involved in heart field formation GO:0060975 7 0.763
neuron development GO:0048666 262 0.762
positive regulation of response to stimulus GO:0048584 80 0.761
response to organic substance GO:0010033 153 0.760
Mouse
epithelial tube morphogenesis GO:0060562 148 0.756
Mouse
axonogenesis GO:0007409 152 0.756
regulation of programmed cell death GO:0043067 101 0.755
Mouse
positive regulation of macromolecule biosynthetic process GO:0010557 59 0.754
formation of primary germ layer GO:0001704 62 0.752
hindbrain development GO:0030902 91 0.746
forebrain neuron development GO:0021884 7 0.740
positive regulation of nervous system development GO:0051962 25 0.733
insulin like growth factor receptor signaling pathway GO:0048009 4 0.733
retina layer formation GO:0010842 24 0.729
regulation of cell development GO:0060284 100 0.729
positive regulation of stem cell proliferation GO:2000648 1 0.725
retinal ganglion cell axon guidance GO:0031290 35 0.721
semicircular canal development GO:0060872 24 0.721
organ formation GO:0048645 17 0.717
Mouse
rostrocaudal neural tube patterning GO:0021903 29 0.710
endocardial cushion development GO:0003197 6 0.710
Mouse
columnar cuboidal epithelial cell differentiation GO:0002065 38 0.709
Mouse
response to chemical GO:0042221 320 0.708
Mouse
inner ear receptor cell differentiation GO:0060113 29 0.708
mechanoreceptor differentiation GO:0042490 37 0.706
neuron fate commitment GO:0048663 26 0.703
negative regulation of apoptotic process GO:0043066 55 0.703
Mouse
endocardium morphogenesis GO:0003160 4 0.699
negative regulation of signal transduction GO:0009968 94 0.695
mesodermal to mesenchymal transition involved in gastrulation GO:0060809 1 0.693
positive regulation of striated muscle cell differentiation GO:0051155 1 0.692
endodermal cell fate determination GO:0007493 2 0.689
regulation of insulin like growth factor receptor signaling pathway GO:0043567 1 0.686
bmp signaling pathway involved in heart development GO:0061312 15 0.673
negative regulation of transcription elongation from rna polymerase ii promoter GO:0034244 1 0.663
regulation of photoreceptor cell differentiation GO:0046532 2 0.662
ventral spinal cord interneuron fate commitment GO:0060579 3 0.661
regulation of glial cell differentiation GO:0045685 4 0.655
renal tubule morphogenesis GO:0061333 1 0.654
Mouse
atrial ventricular junction remodeling GO:0003294 2 0.654
negative regulation of metabolic process GO:0009892 86 0.651
atrioventricular valve formation GO:0003190 3 0.651
endocrine pancreas development GO:0031018 27 0.651
neural crest cell differentiation GO:0014033 72 0.647
regulation of retina development in camera type eye GO:1902866 2 0.644
telencephalon development GO:0021537 14 0.639
Mouse
retina development in camera type eye GO:0060041 146 0.639
macromolecule biosynthetic process GO:0009059 227 0.637
Mouse
cellular macromolecule metabolic process GO:0044260 391 0.633
Mouse
embryonic digestive tract development GO:0048566 4 0.631
head development GO:0060322 303 0.629
midbrain hindbrain boundary development GO:0030917 23 0.627
endodermal cell fate specification GO:0001714 17 0.625
homeostatic process GO:0042592 142 0.625
ventral spinal cord interneuron specification GO:0021521 3 0.619
optic nerve morphogenesis GO:0021631 6 0.619
inner ear receptor cell fate commitment GO:0060120 4 0.617
cell part morphogenesis GO:0032990 246 0.613
somite specification GO:0001757 12 0.611
immune system process GO:0002376 241 0.611
regulation of cell death GO:0010941 103 0.610
Mouse
floor plate morphogenesis GO:0033505 12 0.608
photoreceptor cell development GO:0042461 40 0.606
positive regulation of neurogenesis GO:0050769 24 0.606
epidermal cell differentiation GO:0009913 36 0.602
rhombomere 6 development GO:0021572 4 0.599
fin development GO:0033333 77 0.596
Zebrafish
cardiac muscle tissue morphogenesis GO:0055008 7 0.591
response to growth factor GO:0070848 39 0.587
Mouse
cell fate specification GO:0001708 68 0.587
regionalization GO:0003002 274 0.581
regulation of cell proliferation involved in heart morphogenesis GO:2000136 2 0.572
rhombomere 5 development GO:0021571 4 0.572
tube morphogenesis GO:0035239 349 0.569
positive regulation of cell differentiation GO:0045597 30 0.568
epithelial cell differentiation GO:0030855 116 0.568
Mouse
embryonic appendage morphogenesis GO:0035113 30 0.564
Zebrafish Mouse
determination of dorsal ventral asymmetry GO:0048262 34 0.562
regulation of transcription from rna polymerase ii promoter GO:0006357 114 0.560
Mouse
mesoderm morphogenesis GO:0048332 51 0.560
Mouse
hemopoiesis GO:0030097 183 0.560
cardiac atrium morphogenesis GO:0003209 2 0.558
aorta development GO:0035904 4 0.557
Mouse
vasculogenesis GO:0001570 41 0.556
regulation of cell proliferation GO:0042127 37 0.553
Mouse
mesenchyme morphogenesis GO:0072132 5 0.551
Mouse
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.548
Mouse
positive regulation of glial cell differentiation GO:0045687 1 0.545
regulation of epithelial cell differentiation GO:0030856 7 0.545
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 42 0.544
Mouse
negative regulation of muscle organ development GO:0048635 5 0.539
mesenchymal cell development GO:0014031 78 0.536
Mouse
neuron differentiation GO:0030182 353 0.535
endodermal cell differentiation GO:0035987 19 0.535
tissue remodeling GO:0048771 4 0.534
endodermal cell fate commitment GO:0001711 18 0.528
carboxylic acid catabolic process GO:0046395 3 0.524
negative regulation of epithelial cell proliferation GO:0050680 1 0.520
regulation of organ morphogenesis GO:2000027 35 0.520
Mouse
negative regulation of cell communication GO:0010648 96 0.518
cell proliferation GO:0008283 80 0.517
Mouse
rna biosynthetic process GO:0032774 181 0.516
Mouse
embryo development ending in birth or egg hatching GO:0009792 271 0.515
inner ear receptor cell development GO:0060119 20 0.509
regulation of cardiac muscle cell differentiation GO:2000725 1 0.509
positive regulation of cellular process GO:0048522 201 0.506
odontogenesis GO:0042476 9 0.501
Mouse
embryonic camera type eye development GO:0031076 29 0.495
retinal pigment epithelium development GO:0003406 8 0.495
bmp signaling pathway GO:0030509 52 0.494
Mouse
regulation of biomineral tissue development GO:0070167 2 0.493
signal transduction downstream of smoothened GO:0007227 1 0.492
response to endogenous stimulus GO:0009719 83 0.488
Mouse
fin regeneration GO:0031101 51 0.486
single organism localization GO:1902578 225 0.481
negative regulation of cellular biosynthetic process GO:0031327 55 0.473
positive regulation of cell death GO:0010942 29 0.470
determination of pancreatic left right asymmetry GO:0035469 11 0.466
hindbrain formation GO:0021576 3 0.464
nephron tubule morphogenesis GO:0072078 1 0.460
Mouse
glial cell fate specification GO:0021780 4 0.460
neuroblast proliferation GO:0007405 2 0.457
inner ear morphogenesis GO:0042472 63 0.453
periodic partitioning GO:0007365 1 0.443
cellular response to chemical stimulus GO:0070887 157 0.442
Mouse
cardiogenic plate morphogenesis GO:0003142 1 0.438
positive regulation of signaling GO:0023056 56 0.429
negative regulation of cell differentiation GO:0045596 46 0.427
regulation of macromolecule biosynthetic process GO:0010556 225 0.426
Mouse
response to external biotic stimulus GO:0043207 97 0.425
somatic motor neuron differentiation GO:0021523 5 0.418
immune system development GO:0002520 191 0.418
positive regulation of neuron differentiation GO:0045666 12 0.418
keratinocyte differentiation GO:0030216 0 0.414
negative regulation of cellular process GO:0048523 283 0.413
glial cell differentiation GO:0010001 42 0.412
artery morphogenesis GO:0048844 14 0.407
Mouse
regulation of rna biosynthetic process GO:2001141 213 0.403
Mouse
invagination involved in gastrulation with mouth forming second GO:0055109 1 0.398
nephron development GO:0072006 31 0.396
Mouse
cellular response to retinoic acid GO:0071300 1 0.393
cell fate commitment involved in formation of primary germ layer GO:0060795 26 0.392
cell migration involved in heart development GO:0060973 22 0.386
pericardium development GO:0060039 1 0.383
response to hexose GO:0009746 3 0.382
negative regulation of response to stimulus GO:0048585 104 0.381
axon development GO:0061564 166 0.381
heterocycle biosynthetic process GO:0018130 215 0.376
Mouse
cardiac chamber development GO:0003205 19 0.376
regulation of endodermal cell fate specification GO:0042663 15 0.374
ameboidal type cell migration GO:0001667 143 0.373
Mouse
peripheral nervous system development GO:0007422 55 0.373
embryonic skeletal system morphogenesis GO:0048704 93 0.371
heart jogging GO:0003146 40 0.371
negative regulation of cell death GO:0060548 60 0.371
Mouse
gastrulation GO:0007369 208 0.363
axis specification GO:0009798 43 0.362
hematopoietic progenitor cell differentiation GO:0002244 23 0.359
regulation of developmental process GO:0050793 247 0.358
cell projection morphogenesis GO:0048858 244 0.357
negative regulation of anterior neural cell fate commitment of the neural plate GO:0022001 1 0.353
pericardium morphogenesis GO:0003344 1 0.348
negative regulation of neurogenesis GO:0050768 20 0.342
negative regulation of macromolecule biosynthetic process GO:0010558 48 0.340
response to wounding GO:0009611 116 0.339
response to bacterium GO:0009617 58 0.339
cerebellar cortex development GO:0021695 5 0.338
cell death GO:0008219 121 0.337
Mouse
cellular response to lipid GO:0071396 39 0.333
mesoderm formation GO:0001707 43 0.331
Mouse
skeletal system morphogenesis GO:0048705 102 0.330
muscle structure development GO:0061061 196 0.328
endothelium development GO:0003158 25 0.326
protein metabolic process GO:0019538 183 0.324
positive regulation of cell cycle GO:0045787 3 0.317
Mouse
specification of organ identity GO:0010092 2 0.314
Mouse
positive regulation of gliogenesis GO:0014015 2 0.311
nerve development GO:0021675 45 0.307
regulation of transcription dna templated GO:0006355 213 0.302
Mouse
cardiac muscle cell differentiation GO:0055007 30 0.301
regulation of nervous system development GO:0051960 90 0.299
biosynthetic process GO:0009058 294 0.299
Mouse
rhombomere morphogenesis GO:0021593 17 0.293
nephron epithelium development GO:0072009 16 0.290
Mouse
axial mesoderm structural organization GO:0048331 2 0.289
metencephalon development GO:0022037 27 0.288
photoreceptor cell differentiation GO:0046530 55 0.287
ossification GO:0001503 23 0.285
epithelial tube formation GO:0072175 19 0.285
intermediate mesoderm development GO:0048389 2 0.277
regulation of inner ear receptor cell differentiation GO:2000980 1 0.275
hepatocyte differentiation GO:0070365 1 0.273
posterior lateral line neuromast hair cell differentiation GO:0048923 8 0.269
morphogenesis of an epithelial fold GO:0060571 1 0.268
cellular nitrogen compound biosynthetic process GO:0044271 218 0.267
Mouse
regulation of cytokine production GO:0001817 3 0.265
lymphocyte activation GO:0046649 10 0.253
thyroid gland development GO:0030878 12 0.251
forebrain anterior posterior pattern specification GO:0021797 3 0.251
regulation of endothelial cell differentiation GO:0045601 3 0.250
outflow tract morphogenesis GO:0003151 1 0.250
Mouse
renal system development GO:0072001 94 0.248
Mouse
inner ear receptor stereocilium organization GO:0060122 8 0.247
stem cell differentiation GO:0048863 117 0.243
leukocyte proliferation GO:0070661 1 0.239
dorsal ventral pattern formation GO:0009953 125 0.238
embryonic heart tube morphogenesis GO:0003143 108 0.237
Mouse
vasculature development GO:0001944 278 0.237
Mouse
response to fibroblast growth factor GO:0071774 22 0.237
Mouse
ventral midline development GO:0007418 13 0.236
regulation of heart morphogenesis GO:2000826 17 0.234
blood vessel endothelial cell differentiation GO:0060837 2 0.234
polarized epithelial cell differentiation GO:0030859 4 0.230
embryonic hemopoiesis GO:0035162 53 0.230
negative regulation of nucleobase containing compound metabolic process GO:0045934 59 0.229
blood vessel morphogenesis GO:0048514 216 0.229
Mouse
programmed cell death GO:0012501 119 0.228
Mouse
endoderm formation GO:0001706 29 0.224
exocrine system development GO:0035272 28 0.224
Zebrafish Mouse
hematopoietic stem cell differentiation GO:0060218 20 0.222
chemotaxis GO:0006935 104 0.217
blood vessel development GO:0001568 246 0.217
Mouse
regulation of neurogenesis GO:0050767 87 0.216
cardioblast migration GO:0003260 7 0.211
defense response GO:0006952 47 0.205
glucose homeostasis GO:0042593 1 0.203
neural retina development GO:0003407 49 0.203
determination of dorsal identity GO:0048263 13 0.201
androgen metabolic process GO:0008209 2 0.201
regulation of neural retina development GO:0061074 2 0.200
positive regulation of sequence specific dna binding transcription factor activity GO:0051091 7 0.200
establishment of cell polarity involved in mesendodermal cell migration GO:0003369 1 0.200
vestibular receptor cell development GO:0060118 3 0.200
cellular response to fibroblast growth factor stimulus GO:0044344 22 0.200
Mouse
olfactory lobe development GO:0021988 4 0.197
iris morphogenesis GO:0061072 1 0.196
cell fate specification involved in pattern specification GO:0060573 3 0.192
cardiocyte differentiation GO:0035051 44 0.191
regulation of axonogenesis GO:0050770 32 0.190
single organism transport GO:0044765 206 0.190
limbic system development GO:0021761 16 0.184
ventricular cardiac muscle cell differentiation GO:0055012 6 0.182
tube formation GO:0035148 25 0.181
neuromuscular process GO:0050905 7 0.179
negative regulation of nitrogen compound metabolic process GO:0051172 59 0.177
regulation of biosynthetic process GO:0009889 250 0.176
Mouse
germ line stem cell division GO:0042078 1 0.173
cell fate determination GO:0001709 7 0.173
erythrocyte homeostasis GO:0034101 55 0.172
positive regulation of fibroblast growth factor receptor signaling pathway GO:0045743 9 0.170
dorsal aorta morphogenesis GO:0035912 3 0.170
regulation of bmp signaling pathway involved in heart jogging GO:2000223 12 0.168
cell proliferation in hindbrain GO:0021534 4 0.168
endoderm development GO:0007492 49 0.167
smoothened signaling pathway GO:0007224 30 0.165
cardiac chamber morphogenesis GO:0003206 12 0.165
regulation of neuron projection development GO:0010975 40 0.164
muscle organ development GO:0007517 101 0.162
wnt signaling pathway GO:0016055 80 0.162
ventricular cardiac muscle tissue morphogenesis GO:0055010 2 0.161
negative regulation of rna biosynthetic process GO:1902679 45 0.160
nephron epithelium morphogenesis GO:0072088 1 0.159
Mouse
stem cell development GO:0048864 82 0.158
Mouse
cellular response to oxygen containing compound GO:1901701 20 0.158
muscle tissue development GO:0060537 110 0.158
regulation of stem cell proliferation GO:0072091 2 0.158
auditory receptor cell morphogenesis GO:0002093 4 0.157
tube closure GO:0060606 1 0.156
regulation of macromolecule metabolic process GO:0060255 317 0.154
Mouse
leukocyte activation GO:0045321 12 0.154
semicircular canal morphogenesis GO:0048752 18 0.154
kidney rudiment formation GO:0072003 3 0.154
patterning of blood vessels GO:0001569 15 0.152
Mouse
embryonic cranial skeleton morphogenesis GO:0048701 90 0.149
tongue morphogenesis GO:0043587 3 0.148
spinal cord dorsal ventral patterning GO:0021513 5 0.148
kidney development GO:0001822 92 0.147
Mouse
positive regulation of cell development GO:0010720 25 0.146
mesendoderm development GO:0048382 10 0.146
Mouse
regulation of sequence specific dna binding transcription factor activity GO:0051090 9 0.143
eye photoreceptor cell differentiation GO:0001754 45 0.143
positive regulation of rna biosynthetic process GO:1902680 57 0.141
axon guidance GO:0007411 86 0.141
response to drug GO:0042493 3 0.140
specification of organ position GO:0010159 3 0.140
muscle cell development GO:0055001 115 0.140
positive regulation of programmed cell death GO:0043068 29 0.139
response to other organism GO:0051707 97 0.139
pronephros morphogenesis GO:0072114 14 0.137
regulation of wnt signaling pathway calcium modulating pathway GO:0008591 3 0.136
pigmentation GO:0043473 85 0.136
abducens nerve development GO:0021560 1 0.136
positive regulation of transcription dna templated GO:0045893 57 0.135
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.134
Mouse
neuron projection guidance GO:0097485 86 0.133
positive regulation of biosynthetic process GO:0009891 68 0.132
positive regulation of neural precursor cell proliferation GO:2000179 1 0.132
nephron morphogenesis GO:0072028 2 0.132
Mouse
embryonic pattern specification GO:0009880 44 0.131
maintenance of location GO:0051235 4 0.129
anterior commissure morphogenesis GO:0021960 3 0.128
nephric duct development GO:0072176 13 0.128
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 50 0.127
neuron projection development GO:0031175 180 0.127
response to stress GO:0006950 263 0.127
cellular response to hormone stimulus GO:0032870 39 0.125
gene expression GO:0010467 252 0.124
Mouse
negative regulation of cytokine production GO:0001818 1 0.124
embryonic neurocranium morphogenesis GO:0048702 15 0.123
death GO:0016265 121 0.123
Mouse
abducens nucleus development GO:0021742 2 0.120
olfactory bulb development GO:0021772 4 0.120
primitive hemopoiesis GO:0060215 27 0.119
establishment of monopolar cell polarity GO:0061162 2 0.118
notochord cell differentiation GO:0060034 18 0.114
positive regulation of cell proliferation GO:0008284 15 0.113
Mouse
striated muscle tissue development GO:0014706 110 0.113
dorsal ventral axis specification GO:0009950 14 0.112
anterior posterior pattern specification GO:0009952 152 0.112
positive regulation of developmental process GO:0051094 50 0.111
proximal distal pattern formation GO:0009954 1 0.111
negative regulation of anterior neural cell fate commitment of the neural plate by wnt signaling pathway GO:0022002 1 0.111
neurological system process GO:0050877 62 0.111
cell cell adhesion involved in gastrulation GO:0070586 4 0.111
negative regulation of catabolic process GO:0009895 3 0.111
positive regulation of cellular metabolic process GO:0031325 94 0.110
embryonic limb morphogenesis GO:0030326 2 0.110
Mouse
convergent extension GO:0060026 118 0.110
rhombomere 5 morphogenesis GO:0021664 1 0.109
heart valve development GO:0003170 14 0.109
nephric duct morphogenesis GO:0072178 7 0.108
paraxial mesoderm development GO:0048339 8 0.106
response to retinoic acid GO:0032526 6 0.105
regulation of fibroblast growth factor receptor signaling pathway GO:0040036 20 0.105
spinal cord oligodendrocyte cell fate specification GO:0021530 2 0.105
heart formation GO:0060914 13 0.105
neuromast hair cell development GO:0035675 6 0.102
bmp signaling pathway involved in heart jogging GO:0003303 14 0.099
epithelial cell fate commitment GO:0072148 11 0.099
epithelial cell morphogenesis GO:0003382 2 0.098
neural plate morphogenesis GO:0001839 7 0.098
Mouse
auditory receptor cell fate determination GO:0042668 2 0.097
axon extension GO:0048675 45 0.097
mesodermal cell fate specification GO:0007501 12 0.097

fgf8a disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
physical disorder DOID:0080015 0 0.480
osteochondrodysplasia DOID:2256 0 0.142
bone development disease DOID:0080006 0 0.142
bone disease DOID:0080001 0 0.142
cleidocranial dysplasia DOID:13994 0 0.142
disease of anatomical entity DOID:7 0 0.142
musculoskeletal system disease DOID:17 0 0.142
connective tissue disease DOID:65 0 0.142
acrocephalosyndactylia DOID:12960 0 0.131
dysostosis DOID:1934 0 0.131
synostosis DOID:11971 0 0.131