Danio rerio

59 known processes

fgfr2

fibroblast growth factor receptor 2

(Aliases: wu:fc56c05,fc56c05,fgfr-2)

fgfr2 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
brain development GO:0007420 293 0.983
negative regulation of biological process GO:0048519 304 0.980
Zebrafish Mouse Rat Fly
heart development GO:0007507 313 0.926
cell motility GO:0048870 244 0.876
Worm Fly
response to external stimulus GO:0009605 264 0.874
Worm Fly
forebrain development GO:0030900 96 0.847
Mouse
locomotion GO:0040011 313 0.842
Worm Fly
blood vessel development GO:0001568 246 0.837
Mouse
olfactory placode development GO:0071698 12 0.836
Zebrafish
pancreas development GO:0031016 84 0.836
cell migration GO:0016477 237 0.825
Worm Fly
response to chemical GO:0042221 320 0.822
Human Zebrafish Mouse Rat Worm
chordate embryonic development GO:0043009 271 0.811
Human Mouse
morphogenesis of an epithelium GO:0002009 333 0.784
Zebrafish Mouse Fly
olfactory bulb development GO:0021772 4 0.767
regulation of transcription dna templated GO:0006355 213 0.760
Mouse
olfactory lobe development GO:0021988 4 0.753
endodermal cell differentiation GO:0035987 19 0.734
Zebrafish Fly
somitogenesis GO:0001756 87 0.725
cellular component movement GO:0006928 335 0.718
Worm Fly
localization of cell GO:0051674 244 0.717
Worm Fly
growth GO:0040007 174 0.684
Zebrafish Mouse Fly
vasculature development GO:0001944 278 0.675
Mouse
blood vessel morphogenesis GO:0048514 216 0.663
Mouse
skeletal system development GO:0001501 181 0.646
Human Mouse
head development GO:0060322 303 0.631
ameboidal type cell migration GO:0001667 143 0.616
Fly
muscle structure development GO:0061061 196 0.609
Mouse Worm Fly
cell proliferation in forebrain GO:0021846 3 0.609
Mouse
hindbrain development GO:0030902 91 0.591
chemotaxis GO:0006935 104 0.584
Worm
regulation of nervous system development GO:0051960 90 0.572
Fly
skin development GO:0043588 54 0.495
Zebrafish Mouse
negative regulation of cellular process GO:0048523 283 0.494
Zebrafish Mouse Rat Fly
cellular response to prostaglandin stimulus GO:0071379 3 0.480
regulation of developmental process GO:0050793 247 0.477
Zebrafish Mouse Fly
connective tissue development GO:0061448 99 0.460
regulation of phospholipase activity GO:0010517 2 0.446
Human
negative regulation of cell development GO:0010721 26 0.444
Fly
regionalization GO:0003002 274 0.438
Zebrafish Mouse
cartilage development GO:0051216 96 0.422
regulation of macromolecule metabolic process GO:0060255 317 0.417
Mouse Fly
heart morphogenesis GO:0003007 156 0.414
Mouse
positive regulation of cellular process GO:0048522 201 0.395
Human Mouse Rat Fly
lymphatic endothelial cell differentiation GO:0060836 1 0.382
camera type eye development GO:0043010 222 0.381
Mouse
posterior lateral line system development GO:0048915 46 0.372
Zebrafish
positive regulation of gene expression GO:0010628 71 0.365
Mouse
skeletal system morphogenesis GO:0048705 102 0.364
Human Mouse
forebrain neuron development GO:0021884 7 0.362
Mouse
epithelial cell differentiation GO:0030855 116 0.354
Mouse Fly
enzyme linked receptor protein signaling pathway GO:0007167 106 0.351
Human Zebrafish Mouse Rat Worm
striated muscle cell differentiation GO:0051146 129 0.350
Fly
dendrite guidance GO:0070983 0 0.344
embryonic skeletal system morphogenesis GO:0048704 93 0.340
Human
endodermal cell fate determination GO:0007493 2 0.340
Fly
ectodermal placode morphogenesis GO:0071697 32 0.322
Zebrafish
negative regulation of axon extension involved in axon guidance GO:0048843 1 0.312
stem cell maintenance GO:0019827 4 0.312
angiogenesis GO:0001525 158 0.311
Mouse
stem cell proliferation GO:0072089 4 0.310
Mouse
regulation of multicellular organismal process GO:0051239 277 0.306
Zebrafish Mouse Fly
negative regulation of gastrulation GO:2000542 11 0.303
Zebrafish
regulation of biological quality GO:0065008 263 0.302
Zebrafish Fly
regulation of transcription from rna polymerase ii promoter GO:0006357 114 0.301
Mouse
regulation of endodermal cell differentiation GO:1903224 15 0.292
Zebrafish
negative regulation of multicellular organismal process GO:0051241 69 0.279
Zebrafish Fly
negative regulation of cell migration GO:0030336 17 0.278
regulation of gastrulation GO:0010470 24 0.276
Zebrafish
developmental growth GO:0048589 166 0.272
Zebrafish Mouse Fly
specification of symmetry GO:0009799 204 0.268
negative regulation of axonogenesis GO:0050771 7 0.267
Fly
regulation of multicellular organismal development GO:2000026 223 0.264
Zebrafish Mouse Fly
transcription from rna polymerase ii promoter GO:0006366 80 0.263
Mouse
endoderm development GO:0007492 49 0.259
Zebrafish Fly
eye development GO:0001654 277 0.258
Mouse
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.258
Mouse
olfactory placode morphogenesis GO:0071699 7 0.257
Zebrafish
sensory organ development GO:0007423 393 0.255
Mouse
signal transduction GO:0007165 455 0.255
Human Zebrafish Mouse Rat Worm Fly
mesodermal cell migration GO:0008078 12 0.254
Fly
behavior GO:0007610 74 0.253
Worm
cellular biosynthetic process GO:0044249 286 0.249
Mouse
negative regulation of endodermal cell differentiation GO:1903225 8 0.249
Zebrafish
synaptic target recognition GO:0008039 1 0.247
taxis GO:0042330 109 0.243
Worm
regulation of cell migration GO:0030334 40 0.241
cellular component morphogenesis GO:0032989 336 0.235
negative regulation of protein phosphorylation GO:0001933 4 0.231
embryonic organ development GO:0048568 381 0.230
Human Mouse
neuron projection guidance GO:0097485 86 0.229
Worm
cell migration involved in heart development GO:0060973 22 0.226
cellular response to chemical stimulus GO:0070887 157 0.224
Human Zebrafish Mouse Rat Worm
epidermis development GO:0008544 48 0.220
Mouse
regulation of response to stimulus GO:0048583 269 0.214
Human Mouse Fly
rna biosynthetic process GO:0032774 181 0.214
Mouse
regulation of rna biosynthetic process GO:2001141 213 0.214
Mouse
positive regulation of nucleic acid templated transcription GO:1903508 57 0.210
Mouse
convergent extension GO:0060026 118 0.210
central nervous system neuron development GO:0021954 29 0.210
Mouse
muscle cell differentiation GO:0042692 139 0.209
Mouse Fly
regulation of cell motility GO:2000145 46 0.209
sexual reproduction GO:0019953 36 0.209
Fly
macromolecule biosynthetic process GO:0009059 227 0.208
Mouse
rna metabolic process GO:0016070 219 0.206
Mouse
negative regulation of epithelial cell migration GO:0010633 1 0.205
cellular macromolecule biosynthetic process GO:0034645 224 0.200
Mouse
stem cell differentiation GO:0048863 117 0.197
Mouse Rat Fly
regulation of gene expression GO:0010468 265 0.194
Mouse
lens development in camera type eye GO:0002088 22 0.191
Mouse
regulation of cellular metabolic process GO:0031323 320 0.190
Human Mouse Fly
tube morphogenesis GO:0035239 349 0.189
Zebrafish Mouse Rat Worm Fly
negative regulation of endodermal cell fate specification GO:0042664 8 0.186
Zebrafish
neural tube development GO:0021915 62 0.184
cell proliferation GO:0008283 80 0.182
regulation of signal transduction GO:0009966 225 0.182
Human Mouse Fly
morphogenesis of a branching epithelium GO:0061138 16 0.181
Mouse Fly
extracellular structure organization GO:0043062 27 0.179
cell projection organization GO:0030030 284 0.178
negative regulation of axon guidance GO:1902668 1 0.177
lipid storage GO:0019915 1 0.177
neuron development GO:0048666 262 0.177
Mouse Worm Fly
negative regulation of neurogenesis GO:0050768 20 0.176
Fly
regulation of cell differentiation GO:0045595 142 0.175
Zebrafish Mouse Fly
endodermal cell fate commitment GO:0001711 18 0.174
Zebrafish Fly
mesodermal cell differentiation GO:0048333 21 0.172
Rat Fly
regulation of cellular component movement GO:0051270 55 0.170
cellular response to fatty acid GO:0071398 3 0.170
inner ear receptor cell differentiation GO:0060113 29 0.168
primary neural tube formation GO:0014020 1 0.168
determination of left right symmetry GO:0007368 179 0.167
morphogenesis of an epithelial sheet GO:0002011 49 0.166
positive regulation of nervous system development GO:0051962 25 0.166
embryonic organ morphogenesis GO:0048562 274 0.166
Human Mouse
nerve development GO:0021675 45 0.164
Zebrafish
axon guidance GO:0007411 86 0.164
Worm
cellular component biogenesis GO:0044085 178 0.162
regulation of endodermal cell fate specification GO:0042663 15 0.161
Zebrafish
fin regeneration GO:0031101 51 0.161
Zebrafish
generation of neurons GO:0048699 385 0.161
Mouse Worm Fly
regulation of macromolecule biosynthetic process GO:0010556 225 0.159
Mouse
regulation of cellular amine metabolic process GO:0033238 0 0.156
positive regulation of transcription from rna polymerase ii promoter GO:0045944 22 0.156
Mouse
multi organism reproductive process GO:0044703 36 0.155
Worm Fly
liver development GO:0001889 96 0.155
positive regulation of macromolecule biosynthetic process GO:0010557 59 0.150
Mouse
embryonic viscerocranium morphogenesis GO:0048703 52 0.149
striated muscle cell development GO:0055002 108 0.149
Fly
gene expression GO:0010467 252 0.148
Mouse
amine metabolic process GO:0009308 2 0.145
regulation of erk1 and erk2 cascade GO:0070372 4 0.144
Mouse
developmental growth involved in morphogenesis GO:0060560 86 0.143
Mouse Fly
regulation of programmed cell death GO:0043067 101 0.143
Mouse
innervation GO:0060384 3 0.143
neuron differentiation GO:0030182 353 0.141
Mouse Worm Fly
central nervous system development GO:0007417 387 0.140
muscle tissue development GO:0060537 110 0.139
Zebrafish Mouse
positive regulation of rna metabolic process GO:0051254 59 0.139
Mouse
response to nutrient GO:0007584 3 0.132
heterocycle biosynthetic process GO:0018130 215 0.130
Mouse
gland development GO:0048732 143 0.130
regulation of protein phosphorylation GO:0001932 18 0.129
Fly
response to fibroblast growth factor GO:0071774 22 0.129
Human Zebrafish Mouse Rat Worm
endothelial cell differentiation GO:0045446 20 0.128
anterior posterior pattern specification GO:0009952 152 0.128
cellular response to organic substance GO:0071310 105 0.128
Human Zebrafish Mouse Rat Worm
cilium assembly GO:0042384 58 0.127
retinoic acid receptor signaling pathway GO:0048384 16 0.127
regulation of endothelial cell proliferation GO:0001936 1 0.127
erk1 and erk2 cascade GO:0070371 4 0.127
Mouse
wnt signaling pathway involved in somitogenesis GO:0090244 2 0.126
embryonic skeletal system development GO:0048706 97 0.123
Human
mechanosensory lateral line system development GO:0048881 49 0.121
Zebrafish
endocrine pancreas development GO:0031018 27 0.121
respiratory system development GO:0060541 5 0.121
Mouse Fly
mechanoreceptor differentiation GO:0042490 37 0.120
embryo development ending in birth or egg hatching GO:0009792 271 0.120
Human Mouse Worm
post embryonic organ development GO:0048569 4 0.120
Fly
locomotory behavior GO:0007626 34 0.119
brain morphogenesis GO:0048854 18 0.118
larval development GO:0002164 2 0.118
Worm Fly
cellular component assembly GO:0022607 170 0.117
regulation of cell cycle GO:0051726 52 0.117
Mouse
somite development GO:0061053 96 0.117
cilium morphogenesis GO:0060271 85 0.114
positive regulation of epithelial cell differentiation GO:0030858 2 0.113
lipid metabolic process GO:0006629 52 0.111
paraxial mesoderm development GO:0048339 8 0.111
glial cell migration GO:0008347 3 0.111
Fly
neuroblast differentiation GO:0014016 1 0.110
determination of bilateral symmetry GO:0009855 204 0.110
positive regulation of rna biosynthetic process GO:1902680 57 0.110
Mouse
determination of liver left right asymmetry GO:0071910 11 0.109
regulation of primary metabolic process GO:0080090 311 0.109
Mouse Fly
lateral line development GO:0048882 66 0.107
Zebrafish
regulation of cellular amino acid metabolic process GO:0006521 0 0.106
segmentation GO:0035282 97 0.104
mesoderm development GO:0007498 88 0.103
negative regulation of cell differentiation GO:0045596 46 0.103
Zebrafish Fly
positive regulation of cell fate commitment GO:0010455 1 0.102
cellular macromolecule metabolic process GO:0044260 391 0.102
Human Zebrafish Mouse Rat Worm Fly
eye morphogenesis GO:0048592 144 0.101
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.101
Mouse
regulation of protein localization to nucleus GO:1900180 2 0.100
epithelial cell development GO:0002064 42 0.100
Mouse Fly
pectoral fin development GO:0033339 50 0.100
response to organic substance GO:0010033 153 0.099
Human Zebrafish Mouse Rat Worm
digestive tract development GO:0048565 265 0.099
Zebrafish Mouse Rat Worm Fly
bone morphogenesis GO:0060349 11 0.098
Mouse
embryonic camera type eye development GO:0031076 29 0.098
cell projection morphogenesis GO:0048858 244 0.098
neural tube formation GO:0001841 16 0.096
gamete generation GO:0007276 33 0.096
Fly
gastrulation GO:0007369 208 0.096
Zebrafish Rat Fly
single organism behavior GO:0044708 24 0.095
cellular amine metabolic process GO:0044106 2 0.095
specification of organ identity GO:0010092 2 0.095
Mouse
cellular ketone metabolic process GO:0042180 11 0.095
posterior lateral line development GO:0048916 38 0.093
Zebrafish
cell cell signaling GO:0007267 52 0.093
Mouse
neuron projection morphogenesis GO:0048812 161 0.093
Mouse Worm Fly
cerebellar granular layer development GO:0021681 3 0.092
tube closure GO:0060606 1 0.090
response to abiotic stimulus GO:0009628 122 0.090
neurological system process GO:0050877 62 0.086
retinal ganglion cell axon guidance GO:0031290 35 0.086
reproduction GO:0000003 40 0.085
Worm Fly
multi organism process GO:0051704 134 0.085
Worm Fly
single organism nuclear import GO:1902593 3 0.083
regulation of cell proliferation GO:0042127 37 0.083
Human Mouse Rat
exocrine system development GO:0035272 28 0.083
Mouse
cell proliferation in midbrain GO:0033278 4 0.083
inner ear receptor cell development GO:0060119 20 0.083
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.082
Mouse Worm Fly
camera type eye morphogenesis GO:0048593 108 0.082
positive regulation of cell differentiation GO:0045597 30 0.080
hair cell differentiation GO:0035315 32 0.080
stem cell division GO:0017145 1 0.079
Mouse
negative regulation of non canonical wnt signaling pathway GO:2000051 1 0.077
bone development GO:0060348 14 0.077
Mouse
response to stress GO:0006950 263 0.077
Zebrafish Fly
retina development in camera type eye GO:0060041 146 0.074
forebrain regionalization GO:0021871 4 0.073
skin morphogenesis GO:0043589 7 0.073
Zebrafish Mouse
regulation of biosynthetic process GO:0009889 250 0.073
Mouse
positive regulation of lipase activity GO:0060193 1 0.073
Human
regulation of extrinsic apoptotic signaling pathway GO:2001236 3 0.072
positive regulation of nucleobase containing compound metabolic process GO:0045935 69 0.071
Mouse
negative regulation of endothelial cell migration GO:0010596 1 0.071
transcription dna templated GO:0006351 181 0.071
Mouse
adult behavior GO:0030534 2 0.070
negative regulation of neuron differentiation GO:0045665 10 0.069
Fly
regulation of embryonic development GO:0045995 47 0.069
Zebrafish
exocrine pancreas development GO:0031017 28 0.068
regulation of cytoplasmic transport GO:1903649 4 0.067
cellular response to endogenous stimulus GO:0071495 68 0.067
Human Zebrafish Mouse Rat Worm
regulation of cellular ketone metabolic process GO:0010565 7 0.066
regulation of cellular protein metabolic process GO:0032268 52 0.066
Fly
cellular protein metabolic process GO:0044267 129 0.066
Human Zebrafish Rat Worm Fly
organic cyclic compound biosynthetic process GO:1901362 223 0.065
Mouse
maintenance of location GO:0051235 4 0.065
negative regulation of cell motility GO:2000146 17 0.064
organic acid metabolic process GO:0006082 31 0.064
lateral line system development GO:0048925 76 0.064
Zebrafish
forebrain neuron differentiation GO:0021879 14 0.064
Mouse
cell fate specification involved in pattern specification GO:0060573 3 0.064
cellular response to nutrient levels GO:0031669 2 0.063
multicellular organismal reproductive process GO:0048609 35 0.063
Worm Fly
cell migration involved in heart formation GO:0060974 10 0.062
stem cell development GO:0048864 82 0.062
Rat
cellular nitrogen compound biosynthetic process GO:0044271 218 0.061
Mouse
cell part morphogenesis GO:0032990 246 0.061
cilium organization GO:0044782 71 0.061
regulation of phosphorylation GO:0042325 26 0.061
Human Mouse Fly
hepaticobiliary system development GO:0061008 98 0.061
cell migration to the midline involved in heart development GO:0003318 12 0.061
neuron projection development GO:0031175 180 0.060
Mouse Worm Fly
somatic stem cell maintenance GO:0035019 1 0.060
cardioblast differentiation GO:0010002 9 0.059
Fly
negative regulation of nucleic acid templated transcription GO:1903507 45 0.059
Mouse
positive regulation of biological process GO:0048518 253 0.059
Human Mouse Rat Fly
muscle fiber development GO:0048747 52 0.059
Fly
dorsal ventral pattern formation GO:0009953 125 0.059
Zebrafish
negative regulation of locomotion GO:0040013 18 0.059
response to radiation GO:0009314 51 0.058
regulation of cell development GO:0060284 100 0.057
Fly
aging GO:0007568 2 0.057
cellular amino acid metabolic process GO:0006520 7 0.056
nucleic acid templated transcription GO:0097659 181 0.056
Mouse
muscle cell development GO:0055001 115 0.055
Fly
regulation of epithelial cell proliferation GO:0050678 3 0.055
Mouse Rat
myotube differentiation GO:0014902 45 0.055
response to drug GO:0042493 3 0.054
oocyte maturation GO:0001556 4 0.054
lipid biosynthetic process GO:0008610 22 0.054
chondrocyte development GO:0002063 4 0.053
negative regulation of developmental process GO:0051093 65 0.053
Zebrafish Fly
cell projection assembly GO:0030031 64 0.053
regulation of nucleic acid templated transcription GO:1903506 213 0.053
Mouse
cellular aromatic compound metabolic process GO:0006725 295 0.052
Mouse
phagocytosis GO:0006909 3 0.052
Worm
protein import into nucleus GO:0006606 3 0.052
negative regulation of metabolic process GO:0009892 86 0.052
Mouse
epiboly GO:0090504 41 0.050
response to biotic stimulus GO:0009607 97 0.050
Fly
cardiac cell fate commitment GO:0060911 1 0.050
negative regulation of signal transduction GO:0009968 94 0.050
forebrain anterior posterior pattern specification GO:0021797 3 0.049
response to wounding GO:0009611 116 0.049
Zebrafish
regulation of reproductive process GO:2000241 4 0.049
Mouse
cellular process involved in reproduction in multicellular organism GO:0022412 28 0.049
Fly
negative chemotaxis GO:0050919 1 0.049
telencephalon development GO:0021537 14 0.048
homeostatic process GO:0042592 142 0.048
Zebrafish
regulation of dna replication GO:0006275 3 0.048
axonogenesis involved in innervation GO:0060385 1 0.048
chemical homeostasis GO:0048878 49 0.048
wound healing GO:0042060 90 0.048
Zebrafish
regulation of cellular biosynthetic process GO:0031326 245 0.047
Mouse
nucleic acid metabolic process GO:0090304 244 0.047
Mouse
negative regulation of phosphorylation GO:0042326 6 0.047
neuronal stem cell maintenance GO:0097150 2 0.046
positive regulation of protein kinase b signaling GO:0051897 1 0.046
positive regulation of signaling GO:0023056 56 0.046
Human Mouse Fly
axon development GO:0061564 166 0.046
Mouse Worm Fly
retina morphogenesis in camera type eye GO:0060042 79 0.045
photoreceptor cell differentiation GO:0046530 55 0.045
negative regulation of nucleobase containing compound metabolic process GO:0045934 59 0.045
Mouse
axonogenesis GO:0007409 152 0.045
Mouse Worm Fly
epidermal cell differentiation GO:0009913 36 0.045
regulation of locomotion GO:0040012 55 0.045
cell recognition GO:0008037 19 0.045
digestive tract morphogenesis GO:0048546 231 0.045
Zebrafish Mouse Rat Worm Fly
system process GO:0003008 185 0.044
outflow tract morphogenesis GO:0003151 1 0.044
Mouse
response to vitamin GO:0033273 3 0.044
axon extension GO:0048675 45 0.044
Fly
multicellular organism growth GO:0035264 4 0.044
Mouse
diencephalon development GO:0021536 58 0.044
positive regulation of epithelial cell proliferation GO:0050679 1 0.043
Mouse
neuron migration GO:0001764 22 0.043
skeletal muscle organ development GO:0060538 78 0.043
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 50 0.043
endochondral bone morphogenesis GO:0060350 8 0.043
urogenital system development GO:0001655 97 0.043
Mouse Fly
sensory organ morphogenesis GO:0090596 200 0.043
Mouse
ectodermal placode development GO:0071696 37 0.043
Zebrafish
establishment of localization GO:0051234 244 0.043
Mouse Worm
regulation of cell communication GO:0010646 232 0.043
Human Mouse Fly
carbohydrate homeostasis GO:0033500 1 0.042
negative regulation of cell projection organization GO:0031345 9 0.042
Fly
positive regulation of cell substrate adhesion GO:0010811 1 0.042
endothelial cell proliferation GO:0001935 11 0.042
dopaminergic neuron differentiation GO:0071542 14 0.041
single organism metabolic process GO:0044710 217 0.041
Human Mouse Fly
embryonic appendage morphogenesis GO:0035113 30 0.041
epithelial tube morphogenesis GO:0060562 148 0.041
Mouse Fly
regulation of neurogenesis GO:0050767 87 0.041
Fly
positive regulation of biosynthetic process GO:0009891 68 0.040
Mouse
mesoderm morphogenesis GO:0048332 51 0.040
Rat Fly
positive regulation of map kinase activity GO:0043406 3 0.040
Fly
positive regulation of immune response GO:0050778 11 0.040
Fly
nitrogen compound metabolic process GO:0006807 319 0.040
Mouse
regulation of lipase activity GO:0060191 2 0.040
Human
activation of mapk activity GO:0000187 3 0.040
Fly
lateral inhibition GO:0046331 1 0.039
response to growth factor GO:0070848 39 0.039
Human Zebrafish Mouse Rat Worm
cellular response to acid chemical GO:0071229 8 0.039
negative regulation of response to stimulus GO:0048585 104 0.039
negative regulation of cellular component movement GO:0051271 18 0.039
cellular response to growth factor stimulus GO:0071363 39 0.039
Human Zebrafish Mouse Rat Worm
branching morphogenesis of a nerve GO:0048755 4 0.039
Mouse
glucose homeostasis GO:0042593 1 0.039
immune system process GO:0002376 241 0.039
Mouse Fly
regulation of signaling GO:0023051 235 0.039
Human Mouse Fly
intracellular receptor signaling pathway GO:0030522 30 0.038
endodermal digestive tract morphogenesis GO:0061031 2 0.038
Mouse
cell adhesion mediated by integrin GO:0033627 1 0.038
organic substance biosynthetic process GO:1901576 289 0.038
Mouse
regulation of chondrocyte differentiation GO:0032330 1 0.038
oligodendrocyte development GO:0014003 7 0.038
neural precursor cell proliferation GO:0061351 20 0.038
regulation of multicellular organism growth GO:0040014 4 0.038
Mouse
cell fate commitment involved in formation of primary germ layer GO:0060795 26 0.037
Zebrafish Fly
muscle organ development GO:0007517 101 0.037
Mouse Worm Fly
negative regulation of cell fate specification GO:0009996 11 0.036
Zebrafish
negative regulation of epithelial cell proliferation GO:0050680 1 0.036
Rat
erythrocyte differentiation GO:0030218 54 0.036
organelle assembly GO:0070925 110 0.036
embryonic limb morphogenesis GO:0030326 2 0.036
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 42 0.036
Human Zebrafish Mouse Rat Worm
regulation of epithelial to mesenchymal transition GO:0010717 3 0.036
patterning of blood vessels GO:0001569 15 0.036
embryonic camera type eye formation GO:0060900 10 0.035
ear morphogenesis GO:0042471 64 0.035
Mouse
cerebellar granular layer formation GO:0021684 3 0.035
multicellular organismal response to stress GO:0033555 2 0.035
immune response GO:0006955 28 0.035
Fly
regulation of organ growth GO:0046620 3 0.035
Mouse
negative regulation of nervous system development GO:0051961 22 0.034
Fly
formation of primary germ layer GO:0001704 62 0.034
Zebrafish Rat Fly
vasculogenesis GO:0001570 41 0.034
embryonic heart tube development GO:0035050 133 0.034
phosphorus metabolic process GO:0006793 109 0.034
Human Zebrafish Mouse Rat Worm Fly
bmp signaling pathway GO:0030509 52 0.034
organic substance catabolic process GO:1901575 28 0.034
Worm
positive regulation of translation GO:0045727 1 0.034
protein localization GO:0008104 40 0.034
positive regulation of cellular amine metabolic process GO:0033240 0 0.033
positive regulation of cell fate specification GO:0042660 1 0.033
lateral mesoderm development GO:0048368 23 0.033
macromolecule localization GO:0033036 54 0.033
biosynthetic process GO:0009058 294 0.033
Mouse
negative regulation of cell communication GO:0010648 96 0.033
response to bacterium GO:0009617 58 0.033
Fly
cardioblast migration GO:0003260 7 0.033
cell surface receptor signaling pathway GO:0007166 325 0.033
Human Zebrafish Mouse Rat Worm
epithelial cell migration GO:0010631 25 0.033
Fly
negative regulation of cellular component organization GO:0051129 16 0.032
Mouse Fly
hemopoiesis GO:0030097 183 0.032
Mouse
cardioblast migration to the midline involved in heart field formation GO:0060975 7 0.032
embryonic cranial skeleton morphogenesis GO:0048701 90 0.032
Human
developmental maturation GO:0021700 34 0.032
positive regulation of cellular biosynthetic process GO:0031328 68 0.032
Mouse
response to glucose GO:0009749 3 0.032
positive regulation of cell motility GO:2000147 11 0.031
positive regulation of neurogenesis GO:0050769 24 0.031
digestive system development GO:0055123 289 0.031
Zebrafish Mouse Rat Worm Fly
negative regulation of phosphorus metabolic process GO:0010563 13 0.031
negative regulation of cell growth GO:0030308 7 0.031
Fly
central nervous system myelination GO:0022010 2 0.030
negative regulation of blood vessel endothelial cell migration GO:0043537 1 0.030
extracellular matrix organization GO:0030198 27 0.030
single organism reproductive process GO:0044702 40 0.030
Mouse Worm Fly
negative regulation of cellular metabolic process GO:0031324 77 0.030
Mouse
aromatic compound biosynthetic process GO:0019438 217 0.030
Mouse
determination of left right asymmetry in lateral mesoderm GO:0003140 20 0.030
regulation of cellular component organization GO:0051128 86 0.030
Mouse Worm Fly
nucleobase containing compound biosynthetic process GO:0034654 205 0.030
Mouse
regulation of cell activation GO:0050865 1 0.030
endocrine system development GO:0035270 65 0.030
response to light stimulus GO:0009416 46 0.030
positive regulation of cell proliferation GO:0008284 15 0.030
Human Mouse Rat
multicellular organism reproduction GO:0032504 35 0.029
Worm Fly
morphogenesis of embryonic epithelium GO:0016331 30 0.029
Mouse
endothelium development GO:0003158 25 0.029
immune system development GO:0002520 191 0.029
Mouse Fly
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.029
swim bladder development GO:0048794 19 0.029
forebrain neuron fate commitment GO:0021877 1 0.028
neuroblast fate commitment GO:0014017 1 0.028
wnt signaling pathway planar cell polarity pathway GO:0060071 4 0.028
regulation of protein transport GO:0051223 3 0.028
negative regulation of macromolecule metabolic process GO:0010605 76 0.028
Mouse
sensory system development GO:0048880 76 0.028
Zebrafish
negative regulation of cellular protein metabolic process GO:0032269 16 0.028
tube formation GO:0035148 25 0.028
negative regulation of myeloid cell differentiation GO:0045638 1 0.028
transmission of nerve impulse GO:0019226 19 0.028
oligodendrocyte differentiation GO:0048709 23 0.028
response to hormone GO:0009725 48 0.027
regulation of rna metabolic process GO:0051252 224 0.027
Mouse
columnar cuboidal epithelial cell differentiation GO:0002065 38 0.027
Mouse Fly
response to prostaglandin GO:0034694 5 0.027
limb morphogenesis GO:0035108 7 0.027
Mouse
otic vesicle formation GO:0030916 27 0.027
Mouse
skeletal muscle tissue development GO:0007519 67 0.027
cellular protein modification process GO:0006464 100 0.027
Human Zebrafish Rat Worm Fly
positive regulation of cellular component movement GO:0051272 11 0.027
blood circulation GO:0008015 87 0.027
death GO:0016265 121 0.027
reproductive process GO:0022414 40 0.027
Mouse Worm Fly
nuclear transport GO:0051169 4 0.027
regulation of fatty acid metabolic process GO:0019217 1 0.027
regulation of cartilage development GO:0061035 7 0.027
lens morphogenesis in camera type eye GO:0002089 7 0.027
response to hexose GO:0009746 3 0.026
carboxylic acid metabolic process GO:0019752 22 0.026
cell fate determination GO:0001709 7 0.026
Fly
cell migration involved in gastrulation GO:0042074 79 0.026
Fly
cellular lipid metabolic process GO:0044255 36 0.026

fgfr2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
bone development disease DOID:0080006 0 0.698
Human
bone disease DOID:0080001 0 0.698
Human
disease of anatomical entity DOID:7 0 0.698
Human
musculoskeletal system disease DOID:17 0 0.698
Human
connective tissue disease DOID:65 0 0.698
Human
dysostosis DOID:1934 0 0.064
Human
colon carcinoma DOID:1520 0 0.056
large intestine cancer DOID:5672 0 0.056
colon cancer DOID:219 0 0.056
gastrointestinal system cancer DOID:3119 0 0.056
Human
intestinal cancer DOID:10155 0 0.056
cancer DOID:162 0 0.056
Human
disease of cellular proliferation DOID:14566 0 0.056
Human
organ system cancer DOID:0050686 0 0.056
Human
colorectal cancer DOID:9256 0 0.056
synostosis DOID:11971 0 0.039
Human
disease of metabolism DOID:0014667 0 0.032