Danio rerio

0 known processes

fgfr3

fibroblast growth factor receptor 3

(Aliases: wu:fc27h01,fc27h01)

fgfr3 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
nucleic acid templated transcription GO:0097659 181 0.959
Mouse
regulation of multicellular organismal process GO:0051239 277 0.930
Zebrafish Mouse Fly
regulation of metabolic process GO:0019222 359 0.929
Human Mouse Fly
negative regulation of biological process GO:0048519 304 0.925
Zebrafish Mouse Fly
central nervous system development GO:0007417 387 0.918
Zebrafish Mouse Fly
heterocycle metabolic process GO:0046483 290 0.907
Mouse
positive regulation of biological process GO:0048518 253 0.905
Human Mouse Fly
regionalization GO:0003002 274 0.895
Zebrafish
positive regulation of cellular process GO:0048522 201 0.895
Human Mouse Fly
nitrogen compound metabolic process GO:0006807 319 0.888
Mouse
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.878
Mouse
cellular macromolecule biosynthetic process GO:0034645 224 0.874
Mouse
cellular biosynthetic process GO:0044249 286 0.861
Mouse
regulation of cellular biosynthetic process GO:0031326 245 0.859
Mouse
regulation of macromolecule biosynthetic process GO:0010556 225 0.847
Mouse
cellular nitrogen compound biosynthetic process GO:0044271 218 0.842
Mouse
negative regulation of axon guidance GO:1902668 1 0.814
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.808
negative regulation of cellular process GO:0048523 283 0.797
Zebrafish Mouse Fly
forebrain neuron development GO:0021884 7 0.788
negative regulation of axon extension involved in axon guidance GO:0048843 1 0.777
eye development GO:0001654 277 0.765
Mouse
defense response GO:0006952 47 0.763
Fly
organic substance biosynthetic process GO:1901576 289 0.763
Mouse
forebrain development GO:0030900 96 0.759
Mouse
nucleobase containing compound biosynthetic process GO:0034654 205 0.751
Mouse
larval development GO:0002164 2 0.749
Worm Fly
regulation of transcription dna templated GO:0006355 213 0.748
Mouse
single organism reproductive process GO:0044702 40 0.739
Worm Fly
morphogenesis of an epithelium GO:0002009 333 0.739
Zebrafish Mouse Fly
regulation of rna metabolic process GO:0051252 224 0.738
Mouse
organic cyclic compound metabolic process GO:1901360 301 0.716
Mouse
nucleic acid metabolic process GO:0090304 244 0.711
Mouse
developmental growth GO:0048589 166 0.698
Zebrafish Mouse Fly
tissue migration GO:0090130 37 0.673
Fly
brain development GO:0007420 293 0.665
Zebrafish Mouse
regulation of macromolecule metabolic process GO:0060255 317 0.662
Human Mouse Fly
regulation of gene expression GO:0010468 265 0.658
Mouse
rna biosynthetic process GO:0032774 181 0.654
Mouse
rna metabolic process GO:0016070 219 0.648
Mouse
neural tube development GO:0021915 62 0.637
head development GO:0060322 303 0.631
Zebrafish Mouse
macromolecule biosynthetic process GO:0009059 227 0.623
Mouse
positive regulation of macromolecule metabolic process GO:0010604 93 0.623
Human Mouse Fly
gene expression GO:0010467 252 0.621
Mouse
locomotion GO:0040011 313 0.620
Worm Fly
regulation of biosynthetic process GO:0009889 250 0.620
Mouse
regulation of primary metabolic process GO:0080090 311 0.618
Human Mouse Fly
regulation of cellular metabolic process GO:0031323 320 0.604
Human Mouse Fly
positive regulation of transport GO:0051050 2 0.595
system process GO:0003008 185 0.575
Mouse
anterior posterior axon guidance GO:0033564 5 0.575
mesenchyme development GO:0060485 127 0.556
Zebrafish Fly
positive regulation of rna metabolic process GO:0051254 59 0.548
negative regulation of multicellular organismal process GO:0051241 69 0.542
Zebrafish Mouse Fly
transcription dna templated GO:0006351 181 0.529
Mouse
localization of cell GO:0051674 244 0.528
Worm Fly
defense response to other organism GO:0098542 33 0.527
Fly
cellular protein metabolic process GO:0044267 129 0.525
Human Zebrafish Mouse Worm Fly
neuron differentiation GO:0030182 353 0.524
Mouse Worm Fly
axon guidance GO:0007411 86 0.521
Worm
cellular component morphogenesis GO:0032989 336 0.518
Zebrafish Mouse Worm Fly
taxis GO:0042330 109 0.517
Worm
response to external stimulus GO:0009605 264 0.514
Worm Fly
response to biotic stimulus GO:0009607 97 0.510
Fly
chordate embryonic development GO:0043009 271 0.510
cell motility GO:0048870 244 0.505
Worm Fly
positive regulation of cellular metabolic process GO:0031325 94 0.493
Human Mouse Fly
regulation of apoptotic process GO:0042981 98 0.488
Mouse
female sex differentiation GO:0046660 4 0.486
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 42 0.478
Human Zebrafish Mouse Worm
cell migration GO:0016477 237 0.478
Worm Fly
response to other organism GO:0051707 97 0.475
Fly
organic cyclic compound biosynthetic process GO:1901362 223 0.469
Mouse
central nervous system neuron development GO:0021954 29 0.458
negative regulation of axon extension GO:0030517 7 0.455
Fly
aromatic compound biosynthetic process GO:0019438 217 0.432
Mouse
negative regulation of neuron differentiation GO:0045665 10 0.427
Fly
heterocycle biosynthetic process GO:0018130 215 0.425
Mouse
cellular aromatic compound metabolic process GO:0006725 295 0.422
Mouse
negative regulation of cell projection organization GO:0031345 9 0.417
Fly
positive regulation of biosynthetic process GO:0009891 68 0.414
negative regulation of cell morphogenesis involved in differentiation GO:0010771 8 0.409
Fly
positive regulation of nucleic acid templated transcription GO:1903508 57 0.408
dendrite guidance GO:0070983 0 0.407
circulatory system process GO:0003013 87 0.406
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.393
Mouse
cell part morphogenesis GO:0032990 246 0.390
Zebrafish Mouse Worm Fly
regulation of nucleic acid templated transcription GO:1903506 213 0.389
Mouse
chemotaxis GO:0006935 104 0.386
Worm
positive regulation of cell cycle GO:0045787 3 0.382
telencephalon development GO:0021537 14 0.382
regulation of programmed cell death GO:0043067 101 0.380
Mouse
small molecule metabolic process GO:0044281 77 0.373
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.371
cartilage development GO:0051216 96 0.368
Mouse
nucleobase containing compound metabolic process GO:0006139 274 0.367
Mouse
generation of neurons GO:0048699 385 0.359
Mouse Worm Fly
sensory organ morphogenesis GO:0090596 200 0.358
Mouse
growth GO:0040007 174 0.353
Zebrafish Mouse Fly
female gonad development GO:0008585 4 0.352
hematopoietic or lymphoid organ development GO:0048534 191 0.348
Fly
response to stress GO:0006950 263 0.348
Zebrafish Mouse Fly
sensory organ development GO:0007423 393 0.346
Mouse
regulation of axonogenesis GO:0050770 32 0.342
Fly
positive regulation of cellular biosynthetic process GO:0031328 68 0.340
regulation of cell development GO:0060284 100 0.339
Mouse Fly
epithelial cell migration GO:0010631 25 0.337
Fly
glial cell migration GO:0008347 3 0.335
Fly
embryonic organ morphogenesis GO:0048562 274 0.329
biosynthetic process GO:0009058 294 0.327
Mouse
apoptotic process GO:0006915 116 0.323
Human Mouse
positive regulation of epithelial cell proliferation GO:0050679 1 0.322
Mouse
heart development GO:0007507 313 0.319
Zebrafish Fly
olfactory lobe development GO:0021988 4 0.305
extrinsic apoptotic signaling pathway GO:0097191 3 0.301
Human
regulation of anatomical structure morphogenesis GO:0022603 130 0.291
Zebrafish Fly
positive regulation of metabolic process GO:0009893 108 0.284
Human Mouse Fly
negative regulation of gene expression GO:0010629 65 0.281
Mouse
olfactory bulb axon guidance GO:0071678 3 0.281
cellular nitrogen compound metabolic process GO:0034641 290 0.277
Mouse
somitogenesis GO:0001756 87 0.277
regulation of transcription from rna polymerase ii promoter GO:0006357 114 0.276
Mouse
regulation of signaling GO:0023051 235 0.274
Human Mouse Fly
cognition GO:0050890 1 0.272
cellular component assembly involved in morphogenesis GO:0010927 107 0.271
Zebrafish
skeletal system development GO:0001501 181 0.269
Mouse
cellular macromolecule metabolic process GO:0044260 391 0.269
Human Zebrafish Mouse Worm Fly
regulation of multicellular organismal development GO:2000026 223 0.267
Zebrafish Mouse Fly
regulation of axon extension GO:0030516 24 0.264
Fly
segmentation GO:0035282 97 0.262
regulation of neurogenesis GO:0050767 87 0.261
Mouse Fly
hemopoiesis GO:0030097 183 0.260
positive regulation of rna biosynthetic process GO:1902680 57 0.259
pigmentation GO:0043473 85 0.257
blood circulation GO:0008015 87 0.255
connective tissue development GO:0061448 99 0.254
Mouse
positive regulation of protein metabolic process GO:0051247 23 0.247
Human Mouse Fly
gland development GO:0048732 143 0.247
Zebrafish Fly
regulation of response to stress GO:0080134 36 0.246
Fly
regulation of extrinsic apoptotic signaling pathway GO:2001236 3 0.245
diencephalon development GO:0021536 58 0.245
immune response GO:0006955 28 0.242
Fly
regulation of epithelial cell proliferation GO:0050678 3 0.239
Mouse
embryonic viscerocranium morphogenesis GO:0048703 52 0.237
regulation of biological quality GO:0065008 263 0.236
Zebrafish Mouse Fly
stem cell differentiation GO:0048863 117 0.232
Mouse Fly
cellular amine metabolic process GO:0044106 2 0.229
regulation of rna biosynthetic process GO:2001141 213 0.227
Mouse
epithelial tube morphogenesis GO:0060562 148 0.225
Fly
maintenance of location GO:0051235 4 0.223
cellular response to endogenous stimulus GO:0071495 68 0.223
Human Zebrafish Mouse Worm
positive regulation of gene expression GO:0010628 71 0.221
exocrine system development GO:0035272 28 0.220
cell surface receptor signaling pathway GO:0007166 325 0.218
Human Zebrafish Mouse Worm
protein modification process GO:0036211 100 0.218
Human Zebrafish Mouse Worm Fly
regulation of protein metabolic process GO:0051246 56 0.216
Human Mouse Fly
programmed cell death GO:0012501 119 0.214
Human Mouse
death GO:0016265 121 0.214
Human Mouse
neurological system process GO:0050877 62 0.214
Mouse
lipid storage GO:0019915 1 0.214
negative regulation of signaling GO:0023057 96 0.212
Mouse
negative regulation of cell differentiation GO:0045596 46 0.212
Zebrafish Mouse Fly
positive regulation of transcription from rna polymerase ii promoter GO:0045944 22 0.211
camera type eye development GO:0043010 222 0.209
Mouse
forebrain generation of neurons GO:0021872 14 0.209
regulation of blood circulation GO:1903522 32 0.206
muscle structure development GO:0061061 196 0.206
Worm Fly
positive regulation of macromolecule biosynthetic process GO:0010557 59 0.205
phagocytosis engulfment GO:0006911 1 0.205
Worm
neuron projection development GO:0031175 180 0.202
Mouse Worm Fly
response to chemical GO:0042221 320 0.202
Human Zebrafish Mouse Worm
heart morphogenesis GO:0003007 156 0.200
regulation of cell proliferation GO:0042127 37 0.199
Human Mouse
forebrain neuron differentiation GO:0021879 14 0.198
blood vessel morphogenesis GO:0048514 216 0.197
urogenital system development GO:0001655 97 0.195
Fly
neuron projection morphogenesis GO:0048812 161 0.195
Mouse Worm Fly
response to drug GO:0042493 3 0.194
protein import into nucleus GO:0006606 3 0.193
cardiocyte differentiation GO:0035051 44 0.192
Fly
limbic system development GO:0021761 16 0.192
negative regulation of response to stimulus GO:0048585 104 0.190
Mouse
regulation of cell death GO:0010941 103 0.189
Mouse
blood vessel development GO:0001568 246 0.188
cell morphogenesis involved in differentiation GO:0000904 195 0.187
Mouse Worm Fly
regulation of reproductive process GO:2000241 4 0.187
negative regulation of chemotaxis GO:0050922 4 0.186
central nervous system neuron differentiation GO:0021953 74 0.186
embryonic organ development GO:0048568 381 0.185
immune system process GO:0002376 241 0.185
Fly
regulation of nitrogen compound metabolic process GO:0051171 251 0.181
Mouse
cell proliferation GO:0008283 80 0.178
Human Zebrafish Mouse
hair cell differentiation GO:0035315 32 0.172
organelle organization GO:0006996 227 0.172
Zebrafish Mouse
tube morphogenesis GO:0035239 349 0.171
Zebrafish Mouse Worm Fly
regulation of nervous system development GO:0051960 90 0.171
Mouse Fly
morphogenesis of embryonic epithelium GO:0016331 30 0.169
anterior posterior pattern specification GO:0009952 152 0.168
enzyme linked receptor protein signaling pathway GO:0007167 106 0.167
Human Zebrafish Mouse Worm
negative regulation of epithelial cell migration GO:0010633 1 0.167
development of primary female sexual characteristics GO:0046545 4 0.165
camera type eye morphogenesis GO:0048593 108 0.164
Mouse
synaptic transmission GO:0007268 35 0.163
regulation of system process GO:0044057 40 0.161
epithelium migration GO:0090132 25 0.160
Fly
nuclear transport GO:0051169 4 0.159
cellular component movement GO:0006928 335 0.158
Worm Fly
organonitrogen compound metabolic process GO:1901564 74 0.158
regulation of developmental process GO:0050793 247 0.158
Zebrafish Mouse Fly
cytokine mediated signaling pathway GO:0019221 7 0.157
regulation of response to stimulus GO:0048583 269 0.154
Human Mouse Fly
mesodermal cell migration GO:0008078 12 0.152
Fly
phosphorus metabolic process GO:0006793 109 0.151
Human Zebrafish Mouse Worm Fly
cell death GO:0008219 121 0.150
Human Mouse
regulation of tube size GO:0035150 2 0.150
positive regulation of immune system process GO:0002684 17 0.149
Fly
positive regulation of nucleobase containing compound metabolic process GO:0045935 69 0.148
regulation of phosphate metabolic process GO:0019220 43 0.148
Human Mouse Fly
neuron projection guidance GO:0097485 86 0.147
Worm
cellular process involved in reproduction in multicellular organism GO:0022412 28 0.147
Fly
regulation of cell communication GO:0010646 232 0.142
Human Mouse Fly
regulation of developmental growth GO:0048638 38 0.138
Mouse Fly
neuromuscular process controlling balance GO:0050885 3 0.138
regulation of cellular component organization GO:0051128 86 0.136
Mouse Worm Fly
organelle assembly GO:0070925 110 0.136
Zebrafish
olfactory bulb development GO:0021772 4 0.136
heart process GO:0003015 71 0.135
single organism metabolic process GO:0044710 217 0.134
Human Mouse Fly
negative regulation of cellular metabolic process GO:0031324 77 0.134
Mouse
cranial nerve development GO:0021545 42 0.134
Zebrafish
negative regulation of cell growth GO:0030308 7 0.134
Fly
stem cell proliferation GO:0072089 4 0.131
regulation of signal transduction GO:0009966 225 0.130
Human Mouse Fly
neuroblast proliferation GO:0007405 2 0.130
erk1 and erk2 cascade GO:0070371 4 0.130
Human
forebrain regionalization GO:0021871 4 0.129
regulation of cell differentiation GO:0045595 142 0.128
Zebrafish Mouse Fly
regulation of cell growth GO:0001558 29 0.127
Fly
segment polarity determination GO:0007367 1 0.127
regulation of heart contraction GO:0008016 32 0.123
wound healing GO:0042060 90 0.123
Zebrafish
response to endogenous stimulus GO:0009719 83 0.121
Human Zebrafish Mouse Worm
regulation of localization GO:0032879 104 0.119
epithelial cell differentiation GO:0030855 116 0.118
Mouse Fly
cell fate commitment GO:0045165 99 0.118
Zebrafish Mouse Fly
endoderm development GO:0007492 49 0.117
Zebrafish Fly
cellular protein modification process GO:0006464 100 0.116
Human Zebrafish Mouse Worm Fly
endothelial cell migration GO:0043542 19 0.115
ameboidal type cell migration GO:0001667 143 0.114
Fly
regulation of cellular amino acid metabolic process GO:0006521 0 0.113
dorsal ventral pattern formation GO:0009953 125 0.113
Zebrafish
negative regulation of developmental growth GO:0048640 9 0.112
Mouse Fly
cell projection morphogenesis GO:0048858 244 0.111
Zebrafish Mouse Worm Fly
negative regulation of cell death GO:0060548 60 0.111
positive regulation of developmental process GO:0051094 50 0.110
Mouse
single organism organelle organization GO:1902589 199 0.110
Zebrafish Mouse
negative regulation of programmed cell death GO:0043069 58 0.110
cellular amide metabolic process GO:0043603 4 0.108
striated muscle tissue development GO:0014706 110 0.108
Zebrafish
negative regulation of nervous system development GO:0051961 22 0.108
Mouse Fly
signal transduction by phosphorylation GO:0023014 18 0.107
Human Mouse Fly
positive regulation of molecular function GO:0044093 33 0.107
Human Fly
cellular ketone metabolic process GO:0042180 11 0.107
specification of symmetry GO:0009799 204 0.106
Zebrafish
central nervous system myelination GO:0022010 2 0.106
Mouse
regulation of multicellular organism growth GO:0040014 4 0.105
embryonic heart tube development GO:0035050 133 0.105
regulation of cellular ketone metabolic process GO:0010565 7 0.104
organic acid metabolic process GO:0006082 31 0.104
signal transduction GO:0007165 455 0.103
Human Zebrafish Mouse Worm Fly
positive regulation of defense response GO:0031349 9 0.103
Fly
inner ear morphogenesis GO:0042472 63 0.102
cell proliferation in forebrain GO:0021846 3 0.102
mesenchymal cell development GO:0014031 78 0.101
positive regulation of transcription dna templated GO:0045893 57 0.101
muscle cell differentiation GO:0042692 139 0.100
Fly
ossification GO:0001503 23 0.100
Mouse
negative regulation of apoptotic process GO:0043066 55 0.099
mesoderm development GO:0007498 88 0.099
Zebrafish Fly
regulation of establishment of protein localization GO:0070201 4 0.098
regulation of cellular response to growth factor stimulus GO:0090287 35 0.098
regulation of cellular amine metabolic process GO:0033238 0 0.097
heart contraction GO:0060047 71 0.097
inner ear development GO:0048839 126 0.097
Mouse
regulation of neuron projection development GO:0010975 40 0.096
Fly
fertilization GO:0009566 3 0.096
cellular component assembly GO:0022607 170 0.095
Zebrafish Fly
digestive system development GO:0055123 289 0.094
Zebrafish Mouse Worm Fly
regulation of locomotion GO:0040012 55 0.094
positive regulation of apoptotic process GO:0043065 29 0.093
Mouse
aging GO:0007568 2 0.093
regulation of extent of cell growth GO:0061387 29 0.092
Fly
kidney development GO:0001822 92 0.090
positive regulation of axon guidance GO:1902669 1 0.089
regulation of gastrulation GO:0010470 24 0.089
Zebrafish
positive regulation of innate immune response GO:0045089 8 0.089
Fly
angiogenesis GO:0001525 158 0.089
cell projection organization GO:0030030 284 0.089
Zebrafish Mouse Worm Fly
developmental growth involved in morphogenesis GO:0060560 86 0.089
Fly
phagocytosis GO:0006909 3 0.088
Worm
embryonic skeletal system development GO:0048706 97 0.087
female gamete generation GO:0007292 14 0.086
Fly
neuron migration GO:0001764 22 0.085
positive regulation of map kinase activity GO:0043406 3 0.084
Fly
single organism localization GO:1902578 225 0.084
Worm
positive regulation of cell division GO:0051781 2 0.084
embryo development ending in birth or egg hatching GO:0009792 271 0.084
Worm
skeletal muscle organ development GO:0060538 78 0.082
response to organic substance GO:0010033 153 0.082
Human Zebrafish Mouse Worm
macromolecule modification GO:0043412 111 0.081
Human Zebrafish Mouse Worm Fly
cellular response to external stimulus GO:0071496 2 0.081
negative regulation of developmental process GO:0051093 65 0.080
Zebrafish Mouse Fly
negative regulation of macromolecule biosynthetic process GO:0010558 48 0.079
Mouse
nerve development GO:0021675 45 0.079
Zebrafish Mouse
regulation of defense response GO:0031347 14 0.078
Fly
negative regulation of cell communication GO:0010648 96 0.077
Mouse
gastrulation GO:0007369 208 0.076
Zebrafish Fly
sympathetic ganglion development GO:0061549 2 0.076
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.076
Human Mouse
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.075
Mouse Worm Fly
axon development GO:0061564 166 0.075
Mouse Worm Fly
regulation of protein transport GO:0051223 3 0.075
endodermal cell fate determination GO:0007493 2 0.074
Fly
negative regulation of secretion GO:0051048 2 0.073
multi organism process GO:0051704 134 0.073
Worm Fly
transport GO:0006810 220 0.072
Worm
activation of mapk activity GO:0000187 3 0.071
Fly
patterning of blood vessels GO:0001569 15 0.071
muscle tissue development GO:0060537 110 0.070
Zebrafish
regulation of protein modification process GO:0031399 29 0.070
Human Mouse Fly
positive regulation of catalytic activity GO:0043085 25 0.069
Human Fly
motor neuron axon guidance GO:0008045 23 0.068
carbohydrate derivative metabolic process GO:1901135 61 0.068
renal system development GO:0072001 94 0.067
Fly
regulation of organelle organization GO:0033043 29 0.067
Mouse
positive regulation of cellular amine metabolic process GO:0033240 0 0.067
homeostatic process GO:0042592 142 0.067
Zebrafish
cell projection assembly GO:0030031 64 0.066
Zebrafish Fly
phosphatidylinositol 3 kinase signaling GO:0014065 2 0.066
regulation of map kinase activity GO:0043405 5 0.066
Fly
stem cell maintenance GO:0019827 4 0.065
Mouse
protein localization to nucleus GO:0034504 3 0.065
negative regulation of biosynthetic process GO:0009890 55 0.065
Mouse
odontogenesis of dentin containing tooth GO:0042475 1 0.064
regulation of extrinsic apoptotic signaling pathway in absence of ligand GO:2001239 1 0.064
vasculature development GO:0001944 278 0.064
regulation of organ growth GO:0046620 3 0.064
muscle organ development GO:0007517 101 0.064
Worm Fly
determination of left right symmetry GO:0007368 179 0.063
Zebrafish
regulation of cell projection organization GO:0031344 44 0.063
Worm Fly
myeloid cell differentiation GO:0030099 86 0.063
ear development GO:0043583 127 0.063
Mouse
establishment of localization in cell GO:0051649 77 0.063
Worm
regulation of cellular component movement GO:0051270 55 0.062
single organism nuclear import GO:1902593 3 0.062
regulation of endothelial cell proliferation GO:0001936 1 0.062
Mouse
stem cell development GO:0048864 82 0.061
Mouse
multicellular organism growth GO:0035264 4 0.061
negative regulation of growth GO:0045926 10 0.061
Mouse Fly
lens development in camera type eye GO:0002088 22 0.060
Mouse
regeneration GO:0031099 91 0.060
Zebrafish
positive regulation of multicellular organismal process GO:0051240 52 0.060
protein targeting to nucleus GO:0044744 3 0.059
immune system development GO:0002520 191 0.059
Fly
response to glucocorticoid GO:0051384 1 0.059
neuron development GO:0048666 262 0.058
Mouse Worm Fly
cellular response to chemical stimulus GO:0070887 157 0.057
Human Zebrafish Mouse Worm
tissue regeneration GO:0042246 74 0.057
Zebrafish
posterior lateral line system development GO:0048915 46 0.056
Zebrafish
regulation of molecular function GO:0065009 70 0.056
Human Fly
mitotic cell cycle process GO:1903047 48 0.055
Mouse
membrane invagination GO:0010324 1 0.055
Worm
response to bacterium GO:0009617 58 0.055
Fly
negative regulation of cell development GO:0010721 26 0.054
Mouse Fly
negative regulation of cellular macromolecule biosynthetic process GO:2000113 48 0.054
Mouse
negative regulation of epithelial cell proliferation GO:0050680 1 0.054
Mouse
regulation of endodermal cell differentiation GO:1903224 15 0.054
Zebrafish
developmental process involved in reproduction GO:0003006 27 0.054
Worm Fly
meiotic nuclear division GO:0007126 4 0.054
axonogenesis GO:0007409 152 0.053
Mouse Worm Fly
negative regulation of signal transduction in absence of ligand GO:1901099 1 0.052
regulation of blood vessel size GO:0050880 2 0.052
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 50 0.052
regulation of synapse assembly GO:0051963 3 0.052
mesoderm morphogenesis GO:0048332 51 0.051
Fly
single fertilization GO:0007338 3 0.051
positive regulation of cell adhesion GO:0045785 1 0.050
regulation of stem cell differentiation GO:2000736 4 0.050
positive regulation of nervous system development GO:0051962 25 0.050
cellular amino acid metabolic process GO:0006520 7 0.050
nuclear import GO:0051170 3 0.050
neuroblast differentiation GO:0014016 1 0.050
germ cell migration GO:0008354 8 0.049
Fly
leukocyte proliferation GO:0070661 1 0.049
nucleocytoplasmic transport GO:0006913 4 0.049
protein import GO:0017038 3 0.049
skeletal muscle tissue development GO:0007519 67 0.048
intracellular signal transduction GO:0035556 85 0.048
Human Mouse Fly
lipid metabolic process GO:0006629 52 0.047
Human
forebrain cell migration GO:0021885 1 0.047
cerebellar granular layer development GO:0021681 3 0.047
multi organism reproductive process GO:0044703 36 0.047
Worm Fly
lens fiber cell development GO:0070307 3 0.046
Mouse
regulation of cell shape GO:0008360 1 0.046
Fly
negative regulation of extrinsic apoptotic signaling pathway GO:2001237 2 0.046
cerebellar granule cell differentiation GO:0021707 3 0.045
innate immune response GO:0045087 13 0.045
Fly
axon extension GO:0048675 45 0.045
Fly
negative regulation of nucleic acid templated transcription GO:1903507 45 0.045
Mouse
response to hormone GO:0009725 48 0.045
developmental pigmentation GO:0048066 48 0.044
regulation of anatomical structure size GO:0090066 33 0.044
Fly
heart looping GO:0001947 94 0.044
embryonic cranial skeleton morphogenesis GO:0048701 90 0.044
positive regulation of catabolic process GO:0009896 4 0.044
positive regulation of hydrolase activity GO:0051345 13 0.044
Human
cell fate specification GO:0001708 68 0.044
Zebrafish Fly
response to nutrient GO:0007584 3 0.044
response to radiation GO:0009314 51 0.043
regulation of nucleocytoplasmic transport GO:0046822 2 0.043
developmental programmed cell death GO:0010623 4 0.043
embryonic pattern specification GO:0009880 44 0.043
oxoacid metabolic process GO:0043436 31 0.043
branchiomotor neuron axon guidance GO:0021785 1 0.043
axon midline choice point recognition GO:0016199 4 0.042
neural crest cell migration GO:0001755 42 0.042
gland morphogenesis GO:0022612 13 0.041
response to growth factor GO:0070848 39 0.041
Human Zebrafish Mouse Worm
mononuclear cell proliferation GO:0032943 1 0.041
digestive tract morphogenesis GO:0048546 231 0.041
Zebrafish Mouse Worm Fly
negative regulation of metabolic process GO:0009892 86 0.041
Mouse
compound eye development GO:0048749 2 0.041
epithelial cell proliferation GO:0050673 17 0.040
Mouse
cell morphogenesis GO:0000902 289 0.040
Zebrafish Mouse Worm Fly
negative regulation of transcription dna templated GO:0045892 45 0.040
Mouse
positive regulation of protein kinase b signaling GO:0051897 1 0.040
regulation of cell migration GO:0030334 40 0.040
lamellipodium assembly GO:0030032 1 0.040
cardiac conduction GO:0061337 3 0.040
regulation of intracellular signal transduction GO:1902531 57 0.039
Human Mouse Fly
negative regulation of response to cytokine stimulus GO:0060761 2 0.039
protein metabolic process GO:0019538 183 0.039
Human Zebrafish Mouse Worm Fly
formation of anatomical boundary GO:0048859 14 0.039
regulation of cell motility GO:2000145 46 0.039
positive regulation of muscle cell differentiation GO:0051149 1 0.039
positive regulation of cell differentiation GO:0045597 30 0.038
Mouse
negative regulation of macromolecule metabolic process GO:0010605 76 0.038
Mouse
positive regulation of erk1 and erk2 cascade GO:0070374 2 0.038
Human
fin regeneration GO:0031101 51 0.038
Zebrafish
single organism behavior GO:0044708 24 0.038
response to nutrient levels GO:0031667 10 0.037
establishment of protein localization to organelle GO:0072594 4 0.037
biological adhesion GO:0022610 40 0.037
definitive hemopoiesis GO:0060216 18 0.037
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090101 22 0.037
macromolecule localization GO:0033036 54 0.037
regulation of cell activation GO:0050865 1 0.037
positive regulation of cytokine production GO:0001819 2 0.036
regulation of immune system process GO:0002682 34 0.036
Fly
transcription from rna polymerase ii promoter GO:0006366 80 0.036
Mouse
cellular response to organic substance GO:0071310 105 0.036
Human Zebrafish Mouse Worm
endodermal cell fate commitment GO:0001711 18 0.036
Zebrafish Fly
otic vesicle formation GO:0030916 27 0.036
regulation of cell cycle GO:0051726 52 0.036
Mouse
regulation of response to cytokine stimulus GO:0060759 3 0.036
regulation of cytokine production GO:0001817 3 0.035
negative regulation of protein phosphorylation GO:0001933 4 0.035
protein secretion GO:0009306 1 0.035
hypothalamus development GO:0021854 14 0.035
stem cell division GO:0017145 1 0.035
cilium assembly GO:0042384 58 0.035
Zebrafish
regulation of transferase activity GO:0051338 16 0.035
Human Fly
behavior GO:0007610 74 0.035
Worm
positive regulation of cell activation GO:0050867 1 0.035
peptidyl amino acid modification GO:0018193 16 0.035
Human Zebrafish Mouse
single organismal cell cell adhesion GO:0016337 29 0.035
response to corticosteroid GO:0031960 1 0.034
embryonic skeletal system morphogenesis GO:0048704 93 0.034
epidermal cell fate specification GO:0009957 4 0.034
hematopoietic progenitor cell differentiation GO:0002244 23 0.034
cellular response to oxygen containing compound GO:1901701 20 0.034
extrinsic apoptotic signaling pathway via death domain receptors GO:0008625 1 0.034
cranial nerve morphogenesis GO:0021602 15 0.033
Zebrafish
oocyte development GO:0048599 14 0.033
liver development GO:0001889 96 0.033
Zebrafish
cell cell signaling GO:0007267 52 0.033

fgfr3 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.144
Human
cancer DOID:162 0 0.086
Human
disease of cellular proliferation DOID:14566 0 0.086
Human
musculoskeletal system disease DOID:17 0 0.075
Human
connective tissue disease DOID:65 0 0.075
Human
bone development disease DOID:0080006 0 0.049
Human
bone disease DOID:0080001 0 0.049
Human
organ system cancer DOID:0050686 0 0.042
Human
nervous system disease DOID:863 0 0.040