Danio rerio

73 known processes

fktn

fukutin

(Aliases: im:7163166,zgc:162828,fcmd,MGC162828)

fktn biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
glycosylation GO:0070085 11 0.988
macromolecule glycosylation GO:0043413 9 0.961
protein glycosylation GO:0006486 9 0.943
carbohydrate derivative biosynthetic process GO:1901137 43 0.903
protein o linked glycosylation GO:0006493 4 0.833
regulation of protein glycosylation GO:0060049 3 0.824
glycoprotein biosynthetic process GO:0009101 21 0.779
striated muscle cell differentiation GO:0051146 129 0.622
mannosylation GO:0097502 3 0.529
regulation of biological quality GO:0065008 263 0.327
homeostatic process GO:0042592 142 0.266
determination of heart left right asymmetry GO:0061371 117 0.241
determination of bilateral symmetry GO:0009855 204 0.232
anatomical structure homeostasis GO:0060249 36 0.228
regulation of carbohydrate metabolic process GO:0006109 4 0.201
single organism carbohydrate metabolic process GO:0044723 12 0.198
blood vessel development GO:0001568 246 0.167
carbohydrate metabolic process GO:0005975 12 0.163
regulation of glycoprotein biosynthetic process GO:0010559 3 0.154
glycoprotein metabolic process GO:0009100 23 0.139
regulation of biosynthetic process GO:0009889 250 0.136
organic substance biosynthetic process GO:1901576 289 0.131
extracellular matrix organization GO:0030198 27 0.130
muscle structure development GO:0061061 196 0.128
muscle tissue development GO:0060537 110 0.126
cellular component movement GO:0006928 335 0.124
morphogenesis of an epithelium GO:0002009 333 0.120
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.118
positive regulation of cytokine production GO:0001819 2 0.118
determination of left right symmetry GO:0007368 179 0.114
cellular macromolecule biosynthetic process GO:0034645 224 0.109
regulation of primary metabolic process GO:0080090 311 0.107
regulation of cellular carbohydrate metabolic process GO:0010675 4 0.104
regulation of synapse organization GO:0050807 3 0.090
macromolecule biosynthetic process GO:0009059 227 0.087
cell growth GO:0016049 57 0.086
striated muscle cell development GO:0055002 108 0.085
cellular biosynthetic process GO:0044249 286 0.085
ameboidal type cell migration GO:0001667 143 0.085
response to stress GO:0006950 263 0.084
cognition GO:0050890 1 0.083
cellular carbohydrate metabolic process GO:0044262 4 0.082
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.082
response to chemical GO:0042221 320 0.081
embryonic heart tube morphogenesis GO:0003143 108 0.080
protein metabolic process GO:0019538 183 0.079
erythrocyte development GO:0048821 24 0.078
negative regulation of kinase activity GO:0033673 4 0.078
regulation of cell development GO:0060284 100 0.076
polarized epithelial cell differentiation GO:0030859 4 0.074
regionalization GO:0003002 274 0.073
muscle cell differentiation GO:0042692 139 0.072
regulation of synapse assembly GO:0051963 3 0.072
retina morphogenesis in camera type eye GO:0060042 79 0.071
heterocycle metabolic process GO:0046483 290 0.069
somitogenesis GO:0001756 87 0.066
cellular component morphogenesis GO:0032989 336 0.063
mononuclear cell proliferation GO:0032943 1 0.060
muscle cell development GO:0055001 115 0.059
embryonic skeletal system development GO:0048706 97 0.059
response to hexose GO:0009746 3 0.058
cellular protein metabolic process GO:0044267 129 0.058
striated muscle tissue development GO:0014706 110 0.058
kidney development GO:0001822 92 0.057
organelle organization GO:0006996 227 0.056
cellular macromolecule metabolic process GO:0044260 391 0.054
protein mannosylation GO:0035268 3 0.054
positive regulation of biological process GO:0048518 253 0.052
regulation of cellular protein metabolic process GO:0032268 52 0.052
regulation of cell morphogenesis GO:0022604 42 0.051
cellular protein modification process GO:0006464 100 0.050
positive regulation of stress activated protein kinase signaling cascade GO:0070304 3 0.050
chordate embryonic development GO:0043009 271 0.049
axon extension GO:0048675 45 0.048
nuclear transport GO:0051169 4 0.045
regulation of cellular amine metabolic process GO:0033238 0 0.045
specification of symmetry GO:0009799 204 0.044
response to oxygen levels GO:0070482 25 0.044
regulation of extent of cell growth GO:0061387 29 0.043
dorsal ventral pattern formation GO:0009953 125 0.042
negative regulation of catabolic process GO:0009895 3 0.042
positive regulation of cell activation GO:0050867 1 0.042
peptidyl threonine modification GO:0018210 1 0.041
negative regulation of nuclear division GO:0051784 3 0.040
axon midline choice point recognition GO:0016199 4 0.039
erk1 and erk2 cascade GO:0070371 4 0.038
regulation of cytokine production GO:0001817 3 0.038
regulation of binding GO:0051098 3 0.037
heterocycle biosynthetic process GO:0018130 215 0.037
regulation of production of molecular mediator of immune response GO:0002700 1 0.037
single organism metabolic process GO:0044710 217 0.037
regulation of collateral sprouting in absence of injury GO:0048696 4 0.037
phagocytosis GO:0006909 3 0.036
carbohydrate derivative metabolic process GO:1901135 61 0.036
angiogenesis GO:0001525 158 0.036
biosynthetic process GO:0009058 294 0.035
establishment of localization GO:0051234 244 0.035
regulation of cell morphogenesis involved in differentiation GO:0010769 38 0.035
nucleobase containing compound biosynthetic process GO:0034654 205 0.034
ubiquitin dependent protein catabolic process GO:0006511 3 0.034
positive regulation of protein kinase b signaling GO:0051897 1 0.034
peptidyl serine phosphorylation GO:0018105 1 0.034
phosphatidylinositol 3 kinase signaling GO:0014065 2 0.034
regulation of tube size GO:0035150 2 0.034
gene expression GO:0010467 252 0.033
regulation of metabolic process GO:0019222 359 0.033
protein localization to nucleus GO:0034504 3 0.033
camera type eye morphogenesis GO:0048593 108 0.032
locomotion GO:0040011 313 0.032
cartilage development GO:0051216 96 0.031
negative regulation of chemotaxis GO:0050922 4 0.031
synaptic growth at neuromuscular junction GO:0051124 2 0.031
positive regulation of cellular component movement GO:0051272 11 0.030
transport GO:0006810 220 0.030
cellular component assembly GO:0022607 170 0.030
positive regulation of cellular component biogenesis GO:0044089 3 0.030
positive regulation of epithelial cell differentiation GO:0030858 2 0.030
negative regulation of protein kinase activity GO:0006469 4 0.030
skin development GO:0043588 54 0.030
blood vessel morphogenesis GO:0048514 216 0.030
embryonic pattern specification GO:0009880 44 0.029
sequestering of metal ion GO:0051238 3 0.029
regulation of erk1 and erk2 cascade GO:0070372 4 0.029
regulation of cellular metabolic process GO:0031323 320 0.028
cell projection organization GO:0030030 284 0.028
cellular modified amino acid metabolic process GO:0006575 3 0.028
positive regulation of reproductive process GO:2000243 2 0.028
single organism localization GO:1902578 225 0.028
cellular component assembly involved in morphogenesis GO:0010927 107 0.028
muscle fiber development GO:0048747 52 0.028
cellular nitrogen compound metabolic process GO:0034641 290 0.028
leukocyte proliferation GO:0070661 1 0.028
protein targeting to nucleus GO:0044744 3 0.028
stem cell maintenance GO:0019827 4 0.027
membrane lipid biosynthetic process GO:0046467 2 0.027
inner ear development GO:0048839 126 0.027
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.027
interspecies interaction between organisms GO:0044419 4 0.027
developmental growth involved in morphogenesis GO:0060560 86 0.027
immune system process GO:0002376 241 0.027
nucleocytoplasmic transport GO:0006913 4 0.027
regulation of macromolecule metabolic process GO:0060255 317 0.027
negative regulation of sequestering of calcium ion GO:0051283 4 0.027
somatic muscle development GO:0007525 4 0.026
regulation of cell communication GO:0010646 232 0.026
protein import into nucleus GO:0006606 3 0.026
tube morphogenesis GO:0035239 349 0.026
adherens junction organization GO:0034332 4 0.026
heart development GO:0007507 313 0.026
positive regulation of catabolic process GO:0009896 4 0.026
regulation of cellular biosynthetic process GO:0031326 245 0.026
negative regulation of nervous system development GO:0051961 22 0.026
establishment of localization in cell GO:0051649 77 0.025
regulation of reproductive process GO:2000241 4 0.025
viral process GO:0016032 1 0.025
ossification GO:0001503 23 0.025
negative regulation of phosphate metabolic process GO:0045936 13 0.025
single organism behavior GO:0044708 24 0.025
segment specification GO:0007379 12 0.024
mesenchymal cell development GO:0014031 78 0.024
cellular ion homeostasis GO:0006873 17 0.024
negative regulation of mitosis GO:0045839 3 0.024
establishment of protein localization to organelle GO:0072594 4 0.024
regulation of nervous system development GO:0051960 90 0.024
response to monosaccharide GO:0034284 3 0.024
negative regulation of protein phosphorylation GO:0001933 4 0.024
protein polymerization GO:0051258 4 0.024
positive regulation of secretion GO:0051047 1 0.024
regulation of extrinsic apoptotic signaling pathway GO:2001236 3 0.024
cell cycle g1 s phase transition GO:0044843 1 0.024
rna metabolic process GO:0016070 219 0.024
embryonic heart tube development GO:0035050 133 0.023
production of molecular mediator of immune response GO:0002440 2 0.023
blood circulation GO:0008015 87 0.023
cellular component biogenesis GO:0044085 178 0.023
cellular homeostasis GO:0019725 26 0.023
cell morphogenesis involved in differentiation GO:0000904 195 0.023
carboxylic acid metabolic process GO:0019752 22 0.023
hemopoiesis GO:0030097 183 0.023
alpha amino acid metabolic process GO:1901605 3 0.022
regulation of nucleic acid templated transcription GO:1903506 213 0.022
immune system development GO:0002520 191 0.022
skin morphogenesis GO:0043589 7 0.022
negative regulation of mapk cascade GO:0043409 4 0.022
modification dependent macromolecule catabolic process GO:0043632 3 0.022
regulation of protein catabolic process GO:0042176 1 0.022
cell motility GO:0048870 244 0.022
cellular response to lipopolysaccharide GO:0071222 3 0.021
regeneration GO:0031099 91 0.021
regulation of cytoplasmic transport GO:1903649 4 0.021
regulation of sequestering of calcium ion GO:0051282 4 0.021
regulation of protein import into nucleus GO:0042306 2 0.021
amine metabolic process GO:0009308 2 0.021
macromolecule modification GO:0043412 111 0.021
regulation of signaling GO:0023051 235 0.021
response to external biotic stimulus GO:0043207 97 0.021
regulation of cellular ketone metabolic process GO:0010565 7 0.021
nuclear import GO:0051170 3 0.021
skeletal system development GO:0001501 181 0.020
nitrogen compound metabolic process GO:0006807 319 0.020
cell morphogenesis GO:0000902 289 0.020
regulation of organ growth GO:0046620 3 0.020
female sex differentiation GO:0046660 4 0.020
regulation of cell differentiation GO:0045595 142 0.020
negative regulation of synapse assembly GO:0051964 2 0.020
organelle localization GO:0051640 49 0.020
protein import GO:0017038 3 0.020
regulation of response to biotic stimulus GO:0002831 2 0.019
negative regulation of neurogenesis GO:0050768 20 0.019
regulation of developmental process GO:0050793 247 0.019
response to glucose GO:0009749 3 0.019
neuron projection extension GO:1990138 45 0.019
regulation of protein ubiquitination GO:0031396 3 0.019
neuron development GO:0048666 262 0.019
regulation of cellular amino acid metabolic process GO:0006521 0 0.019
regulation of protein localization to nucleus GO:1900180 2 0.019
filopodium assembly GO:0046847 5 0.019
cell part morphogenesis GO:0032990 246 0.019
cellular amine metabolic process GO:0044106 2 0.019
protein complex localization GO:0031503 1 0.019
cell migration GO:0016477 237 0.019
transcription dna templated GO:0006351 181 0.018
positive regulation of immune effector process GO:0002699 3 0.018
organonitrogen compound metabolic process GO:1901564 74 0.018
symbiosis encompassing mutualism through parasitism GO:0044403 4 0.018
establishment of organelle localization GO:0051656 45 0.018
developmental cell growth GO:0048588 52 0.018
regulation of protein modification by small protein conjugation or removal GO:1903320 3 0.018
positive regulation of transport GO:0051050 2 0.018
regulation of cellular response to growth factor stimulus GO:0090287 35 0.018
positive regulation of cytosolic calcium ion concentration GO:0007204 4 0.018
aging GO:0007568 2 0.018
regulation of mrna splicing via spliceosome GO:0048024 3 0.017
modification dependent protein catabolic process GO:0019941 3 0.017
sequestering of calcium ion GO:0051208 3 0.017
positive regulation of cellular catabolic process GO:0031331 3 0.017
determination of dorsal ventral asymmetry GO:0048262 34 0.017
circulatory system process GO:0003013 87 0.017
negative regulation of extrinsic apoptotic signaling pathway GO:2001237 2 0.017
nucleobase containing compound metabolic process GO:0006139 274 0.017
camera type eye development GO:0043010 222 0.017
growth GO:0040007 174 0.017
regulation of axonogenesis GO:0050770 32 0.017
heart morphogenesis GO:0003007 156 0.017
nucleic acid transport GO:0050657 2 0.017
organic cyclic compound metabolic process GO:1901360 301 0.017
single organism nuclear import GO:1902593 3 0.017
response to drug GO:0042493 3 0.016
multi organism process GO:0051704 134 0.016
regulation of rna biosynthetic process GO:2001141 213 0.016
hormone transport GO:0009914 2 0.016
regulation of cell activation GO:0050865 1 0.016
cell projection morphogenesis GO:0048858 244 0.016
regulation of transcription dna templated GO:0006355 213 0.016
fin development GO:0033333 77 0.016
renal system development GO:0072001 94 0.016
i kappab kinase nf kappab signaling GO:0007249 4 0.016
regulation of cell shape GO:0008360 1 0.015
regulation of oocyte development GO:0060281 3 0.015
regulation of intracellular protein transport GO:0033157 3 0.015
nucleobase containing compound transport GO:0015931 2 0.015
cellular localization GO:0051641 97 0.015
aromatic compound biosynthetic process GO:0019438 217 0.015
positive regulation of cell adhesion GO:0045785 1 0.015
response to carbohydrate GO:0009743 3 0.015
cellular ketone metabolic process GO:0042180 11 0.015
negative regulation of signal transduction in absence of ligand GO:1901099 1 0.015
eye morphogenesis GO:0048592 144 0.015
cellular amino acid metabolic process GO:0006520 7 0.015
cellular response to fibroblast growth factor stimulus GO:0044344 22 0.015
membrane invagination GO:0010324 1 0.015
intracellular signal transduction GO:0035556 85 0.015
behavior GO:0007610 74 0.015
negative regulation of cell cycle process GO:0010948 9 0.015
positive regulation of erk1 and erk2 cascade GO:0070374 2 0.015
microtubule cytoskeleton organization GO:0000226 33 0.015
lymphocyte proliferation GO:0046651 1 0.015
phagocytosis engulfment GO:0006911 1 0.015
cellular amino acid biosynthetic process GO:0008652 2 0.015
developmental growth GO:0048589 166 0.015
multi organism cellular process GO:0044764 2 0.015
myeloid cell differentiation GO:0030099 86 0.014
positive regulation of multi organism process GO:0043902 3 0.014
regulation of filopodium assembly GO:0051489 2 0.014
regulation of nucleocytoplasmic transport GO:0046822 2 0.014
regulation of dendrite development GO:0050773 3 0.014
regulation of cytokine biosynthetic process GO:0042035 1 0.014
cell surface receptor signaling pathway GO:0007166 325 0.014
urogenital system development GO:0001655 97 0.014
negative regulation of mrna splicing via spliceosome GO:0048025 1 0.014
localization of cell GO:0051674 244 0.014
synaptic transmission GO:0007268 35 0.014
embryonic organ development GO:0048568 381 0.014
generation of neurons GO:0048699 385 0.014
ion homeostasis GO:0050801 41 0.014
immunoglobulin mediated immune response GO:0016064 3 0.014
positive regulation of stress activated mapk cascade GO:0032874 3 0.014
regulation of macromolecule biosynthetic process GO:0010556 225 0.013
regulation of dna replication GO:0006275 3 0.013
response to alkaloid GO:0043279 2 0.013
negative regulation of locomotion GO:0040013 18 0.013
cellular component disassembly GO:0022411 1 0.013
retina layer formation GO:0010842 24 0.013
regulation of anatomical structure morphogenesis GO:0022603 130 0.013
cellular response to starvation GO:0009267 1 0.013
epithelial cell differentiation GO:0030855 116 0.013
epithelial cell proliferation involved in liver morphogenesis GO:0072575 2 0.013
embryonic organ morphogenesis GO:0048562 274 0.013
regulation of cell migration GO:0030334 40 0.013
positive regulation of neuron differentiation GO:0045666 12 0.013
single organism transport GO:0044765 206 0.013
immunoglobulin production GO:0002377 1 0.013
cellular response to organic substance GO:0071310 105 0.013
peptidyl threonine phosphorylation GO:0018107 1 0.013
taurine metabolic process GO:0019530 1 0.013
larval development GO:0002164 2 0.013
dna templated transcription initiation GO:0006352 1 0.013
post anal tail morphogenesis GO:0036342 19 0.013
positive regulation of secretion by cell GO:1903532 1 0.013
segmentation GO:0035282 97 0.013
stem cell differentiation GO:0048863 117 0.013
organic cyclic compound biosynthetic process GO:1901362 223 0.013
inner ear receptor cell differentiation GO:0060113 29 0.013
regulation of locomotion GO:0040012 55 0.013
cytoskeleton organization GO:0007010 96 0.013
regulation of cellular component movement GO:0051270 55 0.013
heart jogging GO:0003146 40 0.012
posterior lateral line neuromast development GO:0048919 20 0.012
regulation of nitrogen compound metabolic process GO:0051171 251 0.012
regulation of endothelial cell differentiation GO:0045601 3 0.012
sarcomere organization GO:0045214 26 0.012
signal transduction GO:0007165 455 0.012
peptidyl serine modification GO:0018209 2 0.012
response to external stimulus GO:0009605 264 0.012
g1 s transition of mitotic cell cycle GO:0000082 1 0.012
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 2 0.012
response to growth factor GO:0070848 39 0.012
negative regulation of cell communication GO:0010648 96 0.012
negative regulation of cellular process GO:0048523 283 0.012
positive regulation of lipid metabolic process GO:0045834 1 0.012
neural crest cell development GO:0014032 62 0.012
regulation of phosphate metabolic process GO:0019220 43 0.012
regulation of microtubule cytoskeleton organization GO:0070507 3 0.012
regulation of epithelial to mesenchymal transition GO:0010717 3 0.012
negative regulation of protein serine threonine kinase activity GO:0071901 2 0.012
extracellular structure organization GO:0043062 27 0.012
positive regulation of striated muscle tissue development GO:0045844 1 0.012
negative regulation of rna splicing GO:0033119 1 0.012
positive regulation of peptidyl tyrosine phosphorylation GO:0050731 1 0.012
single organism cell adhesion GO:0098602 29 0.012
exocrine pancreas development GO:0031017 28 0.012
positive regulation of multicellular organismal process GO:0051240 52 0.012
regulation of cardiac muscle contraction GO:0055117 2 0.011
actin cytoskeleton organization GO:0030036 63 0.011
positive regulation of cytoskeleton organization GO:0051495 3 0.011
regulation of multicellular organismal process GO:0051239 277 0.011
positive regulation of i kappab kinase nf kappab signaling GO:0043123 3 0.011
chemical homeostasis GO:0048878 49 0.011
primitive hemopoiesis GO:0060215 27 0.011
cellular response to biotic stimulus GO:0071216 3 0.011
b cell activation GO:0042113 2 0.011
muscle cell migration GO:0014812 4 0.011
protein modification process GO:0036211 100 0.011
fin morphogenesis GO:0033334 53 0.011
positive regulation of epithelial cell migration GO:0010634 2 0.011
protein heterooligomerization GO:0051291 1 0.011
pericardium development GO:0060039 1 0.011
phosphatidylinositol mediated signaling GO:0048015 2 0.011
positive regulation of gene expression GO:0010628 71 0.011
negative regulation of axon extension involved in axon guidance GO:0048843 1 0.011
hormone secretion GO:0046879 2 0.011
negative regulation of map kinase activity GO:0043407 2 0.011
negative regulation of developmental process GO:0051093 65 0.011
cellular response to chemical stimulus GO:0070887 157 0.011
cellular protein catabolic process GO:0044257 4 0.011
regulation of transmembrane transporter activity GO:0022898 2 0.011
response to biotic stimulus GO:0009607 97 0.011
regulation of calcium ion transport GO:0051924 2 0.011
signal transduction by phosphorylation GO:0023014 18 0.011
epithelial tube formation GO:0072175 19 0.011
organelle assembly GO:0070925 110 0.011
extrinsic apoptotic signaling pathway GO:0097191 3 0.011
stem cell development GO:0048864 82 0.011
hormone biosynthetic process GO:0042446 3 0.011
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.011
internal protein amino acid acetylation GO:0006475 2 0.011
negative regulation of cytokine production GO:0001818 1 0.010
regulation of multicellular organismal development GO:2000026 223 0.010
protein acylation GO:0043543 3 0.010
negative regulation of neuron projection development GO:0010977 9 0.010
cellular aromatic compound metabolic process GO:0006725 295 0.010
embryonic skeletal joint development GO:0072498 3 0.010
regulation of neuron projection development GO:0010975 40 0.010
regulation of i kappab kinase nf kappab signaling GO:0043122 4 0.010
vasculature development GO:0001944 278 0.010
regulation of developmental growth GO:0048638 38 0.010
vasculogenesis GO:0001570 41 0.010
interaction with host GO:0051701 4 0.010
lipid catabolic process GO:0016042 4 0.010
regulation of dna damage response signal transduction by p53 class mediator GO:0043516 4 0.010
system process GO:0003008 185 0.010
response to fibroblast growth factor GO:0071774 22 0.010
calcium ion transport into cytosol GO:0060402 3 0.010
inositol lipid mediated signaling GO:0048017 2 0.010
protein acetylation GO:0006473 2 0.010
regulation of glycoprotein metabolic process GO:1903018 3 0.010
coagulation GO:0050817 13 0.010
rna localization GO:0006403 4 0.010
regulation of neuron differentiation GO:0045664 56 0.010
neuron projection regeneration GO:0031102 16 0.010
phosphate containing compound metabolic process GO:0006796 108 0.010

fktn disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
muscular disease DOID:0080000 0 0.444
disease of anatomical entity DOID:7 0 0.444
musculoskeletal system disease DOID:17 0 0.444
myopathy DOID:423 0 0.304
muscle tissue disease DOID:66 0 0.304
muscular dystrophy DOID:9884 0 0.027
disease of cellular proliferation DOID:14566 0 0.025
cancer DOID:162 0 0.022
disease of metabolism DOID:0014667 0 0.019
inherited metabolic disorder DOID:655 0 0.019
congenital muscular dystrophy DOID:0050557 0 0.017
organ system cancer DOID:0050686 0 0.015
large intestine cancer DOID:5672 0 0.013
gastrointestinal system cancer DOID:3119 0 0.013
intestinal cancer DOID:10155 0 0.013
colorectal cancer DOID:9256 0 0.013