Danio rerio

0 known processes

fmnl2b

formin-like 2b

(Aliases: im:7143207)

fmnl2b biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
single organism transport GO:0044765 206 0.263
morphogenesis of an epithelium GO:0002009 333 0.234
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.211
chemotaxis GO:0006935 104 0.210
response to chemical GO:0042221 320 0.199
lipid storage GO:0019915 1 0.186
muscle structure development GO:0061061 196 0.186
cell morphogenesis involved in differentiation GO:0000904 195 0.179
regulation of cellular component organization GO:0051128 86 0.177
response to external stimulus GO:0009605 264 0.166
epithelial tube morphogenesis GO:0060562 148 0.152
cell surface receptor signaling pathway GO:0007166 325 0.149
larval development GO:0002164 2 0.145
taxis GO:0042330 109 0.134
eye development GO:0001654 277 0.125
modification dependent protein catabolic process GO:0019941 3 0.118
regulation of biological quality GO:0065008 263 0.117
cellular component morphogenesis GO:0032989 336 0.115
central nervous system development GO:0007417 387 0.112
mitotic g2 dna damage checkpoint GO:0007095 3 0.111
neuron projection guidance GO:0097485 86 0.109
regulation of heart contraction GO:0008016 32 0.107
modification dependent macromolecule catabolic process GO:0043632 3 0.105
positive regulation of biological process GO:0048518 253 0.102
cellular protein catabolic process GO:0044257 4 0.101
cell projection morphogenesis GO:0048858 244 0.099
heart development GO:0007507 313 0.097
regulation of cell shape GO:0008360 1 0.096
macromolecular complex subunit organization GO:0043933 74 0.095
sequestering of metal ion GO:0051238 3 0.092
establishment of localization GO:0051234 244 0.091
regulation of cell morphogenesis GO:0022604 42 0.090
regulation of system process GO:0044057 40 0.086
regulation of macromolecule metabolic process GO:0060255 317 0.084
response to stress GO:0006950 263 0.082
long chain fatty acid metabolic process GO:0001676 1 0.081
aging GO:0007568 2 0.076
muscle cell differentiation GO:0042692 139 0.073
regulation of metabolic process GO:0019222 359 0.072
regulation of nucleotide catabolic process GO:0030811 2 0.069
striated muscle cell development GO:0055002 108 0.069
striated muscle cell differentiation GO:0051146 129 0.068
calcium ion transport into cytosol GO:0060402 3 0.067
skeletal muscle organ development GO:0060538 78 0.067
cellular component movement GO:0006928 335 0.067
transport GO:0006810 220 0.067
regulation of programmed cell death GO:0043067 101 0.065
brain development GO:0007420 293 0.063
phospholipase c activating g protein coupled receptor signaling pathway GO:0007200 2 0.061
embryonic organ morphogenesis GO:0048562 274 0.060
axon guidance GO:0007411 86 0.057
positive regulation of cell adhesion GO:0045785 1 0.057
positive regulation of cellular process GO:0048522 201 0.057
system process GO:0003008 185 0.057
maintenance of location GO:0051235 4 0.056
intracellular signal transduction GO:0035556 85 0.055
developmental growth GO:0048589 166 0.055
single organism metabolic process GO:0044710 217 0.053
positive regulation of cellular catabolic process GO:0031331 3 0.053
cellular component biogenesis GO:0044085 178 0.052
neuron development GO:0048666 262 0.052
regulation of signaling GO:0023051 235 0.052
blood circulation GO:0008015 87 0.051
response to abiotic stimulus GO:0009628 122 0.051
positive regulation of small gtpase mediated signal transduction GO:0051057 1 0.050
regulation of cell communication GO:0010646 232 0.049
meiotic nuclear division GO:0007126 4 0.049
cell growth GO:0016049 57 0.049
positive regulation of catabolic process GO:0009896 4 0.049
single organism localization GO:1902578 225 0.048
establishment of localization in cell GO:0051649 77 0.047
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.047
proteasomal protein catabolic process GO:0010498 2 0.046
ameboidal type cell migration GO:0001667 143 0.045
protein metabolic process GO:0019538 183 0.045
neuron projection morphogenesis GO:0048812 161 0.045
positive regulation of cell communication GO:0010647 56 0.045
head development GO:0060322 303 0.044
extrinsic apoptotic signaling pathway GO:0097191 3 0.044
growth GO:0040007 174 0.043
sensory organ development GO:0007423 393 0.043
cellular component assembly GO:0022607 170 0.043
water homeostasis GO:0030104 4 0.042
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.042
oxoacid metabolic process GO:0043436 31 0.042
ubiquitin dependent protein catabolic process GO:0006511 3 0.041
axonogenesis GO:0007409 152 0.041
cell part morphogenesis GO:0032990 246 0.040
guanosine containing compound metabolic process GO:1901068 4 0.040
regulation of multicellular organism growth GO:0040014 4 0.040
regulation of response to stimulus GO:0048583 269 0.040
circulatory system process GO:0003013 87 0.040
regulation of signal transduction GO:0009966 225 0.039
chordate embryonic development GO:0043009 271 0.039
divalent inorganic cation homeostasis GO:0072507 22 0.039
homophilic cell adhesion via plasma membrane adhesion molecules GO:0007156 4 0.039
aromatic compound biosynthetic process GO:0019438 217 0.039
behavior GO:0007610 74 0.039
specification of symmetry GO:0009799 204 0.039
regulation of innate immune response GO:0045088 11 0.039
oocyte maturation GO:0001556 4 0.038
mitotic dna integrity checkpoint GO:0044774 4 0.038
biosynthetic process GO:0009058 294 0.038
mitotic g2 m transition checkpoint GO:0044818 3 0.037
regulation of localization GO:0032879 104 0.037
cell motility GO:0048870 244 0.037
single organism organelle organization GO:1902589 199 0.037
heterocycle biosynthetic process GO:0018130 215 0.037
sequestering of calcium ion GO:0051208 3 0.037
gtp metabolic process GO:0046039 4 0.036
signal transduction GO:0007165 455 0.036
axon development GO:0061564 166 0.035
regulation of purine nucleotide catabolic process GO:0033121 2 0.035
gtp catabolic process GO:0006184 2 0.035
convergent extension involved in gastrulation GO:0060027 71 0.034
regulation of blood circulation GO:1903522 32 0.034
adult behavior GO:0030534 2 0.033
striated muscle tissue development GO:0014706 110 0.033
regulation of multicellular organismal development GO:2000026 223 0.033
rna biosynthetic process GO:0032774 181 0.033
cytosolic calcium ion transport GO:0060401 3 0.033
cellular localization GO:0051641 97 0.032
cellular macromolecule metabolic process GO:0044260 391 0.032
neural crest cell differentiation GO:0014033 72 0.032
sensory organ morphogenesis GO:0090596 200 0.032
regulation of cell death GO:0010941 103 0.031
neuron differentiation GO:0030182 353 0.031
cell projection organization GO:0030030 284 0.030
homeostatic process GO:0042592 142 0.029
cell morphogenesis GO:0000902 289 0.029
organic acid metabolic process GO:0006082 31 0.029
muscle cell development GO:0055001 115 0.028
inorganic cation transmembrane transport GO:0098662 50 0.028
organonitrogen compound metabolic process GO:1901564 74 0.028
convergent extension GO:0060026 118 0.027
adherens junction organization GO:0034332 4 0.027
i kappab kinase nf kappab signaling GO:0007249 4 0.027
mitochondrion organization GO:0007005 4 0.027
heart looping GO:0001947 94 0.027
wnt signaling pathway GO:0016055 80 0.027
cellular biosynthetic process GO:0044249 286 0.026
response to topologically incorrect protein GO:0035966 2 0.026
synaptic growth at neuromuscular junction GO:0051124 2 0.026
ras protein signal transduction GO:0007265 7 0.026
guanosine containing compound catabolic process GO:1901069 2 0.026
carboxylic acid metabolic process GO:0019752 22 0.026
regulation of axonogenesis GO:0050770 32 0.026
regulation of gtp catabolic process GO:0033124 2 0.025
regulation of primary metabolic process GO:0080090 311 0.025
immune system development GO:0002520 191 0.025
small molecule metabolic process GO:0044281 77 0.025
phosphatidylinositol mediated signaling GO:0048015 2 0.025
phagocytosis engulfment GO:0006911 1 0.024
tube morphogenesis GO:0035239 349 0.024
membrane invagination GO:0010324 1 0.024
nitrogen compound metabolic process GO:0006807 319 0.024
phosphorylation GO:0016310 69 0.024
nuclear import GO:0051170 3 0.024
regulation of embryonic development GO:0045995 47 0.024
organic cyclic compound biosynthetic process GO:1901362 223 0.023
embryonic organ development GO:0048568 381 0.023
metal ion transport GO:0030001 58 0.022
muscle organ development GO:0007517 101 0.022
g2 dna damage checkpoint GO:0031572 3 0.022
protein dephosphorylation GO:0006470 3 0.022
heart contraction GO:0060047 71 0.022
organic cyclic compound metabolic process GO:1901360 301 0.022
cellular protein metabolic process GO:0044267 129 0.022
embryonic viscerocranium morphogenesis GO:0048703 52 0.022
regulation of cellular component movement GO:0051270 55 0.022
cell death GO:0008219 121 0.022
regulation of neuron differentiation GO:0045664 56 0.021
positive regulation of cellular component biogenesis GO:0044089 3 0.021
myeloid cell differentiation GO:0030099 86 0.021
protein polyubiquitination GO:0000209 4 0.021
regionalization GO:0003002 274 0.021
protein localization to nucleus GO:0034504 3 0.021
cellular response to hypoxia GO:0071456 1 0.021
regulation of anatomical structure morphogenesis GO:0022603 130 0.021
axon extension GO:0048675 45 0.020
camera type eye morphogenesis GO:0048593 108 0.020
regulation of cellular metabolic process GO:0031323 320 0.020
cell migration GO:0016477 237 0.020
developmental growth involved in morphogenesis GO:0060560 86 0.020
regulation of synapse assembly GO:0051963 3 0.020
release of sequestered calcium ion into cytosol GO:0051209 3 0.020
positive regulation of cytokine production GO:0001819 2 0.019
regulation of protein catabolic process GO:0042176 1 0.019
cellular aromatic compound metabolic process GO:0006725 295 0.019
regulation of filopodium assembly GO:0051489 2 0.019
multicellular organism growth GO:0035264 4 0.019
axonal defasciculation GO:0007414 2 0.019
g1 s transition of mitotic cell cycle GO:0000082 1 0.019
cell cycle g1 s phase transition GO:0044843 1 0.019
regulation of cell differentiation GO:0045595 142 0.019
regulation of rho protein signal transduction GO:0035023 2 0.019
pigmentation GO:0043473 85 0.019
localization of cell GO:0051674 244 0.019
odontogenesis of dentin containing tooth GO:0042475 1 0.019
nuclear migration GO:0007097 3 0.019
cellular protein modification process GO:0006464 100 0.019
fatty acid biosynthetic process GO:0006633 4 0.018
heterocycle metabolic process GO:0046483 290 0.018
positive regulation of leukocyte mediated immunity GO:0002705 1 0.018
organelle organization GO:0006996 227 0.018
long chain fatty acid biosynthetic process GO:0042759 1 0.018
glycoprotein metabolic process GO:0009100 23 0.018
negative regulation of biological process GO:0048519 304 0.017
transcription dna templated GO:0006351 181 0.017
neuron recognition GO:0008038 18 0.017
single organismal cell cell adhesion GO:0016337 29 0.017
protein complex biogenesis GO:0070271 30 0.017
positive regulation of ras protein signal transduction GO:0046579 1 0.017
actin cytoskeleton organization GO:0030036 63 0.017
erk1 and erk2 cascade GO:0070371 4 0.017
regulation of nucleoside metabolic process GO:0009118 2 0.017
ion transmembrane transport GO:0034220 91 0.017
determination of heart left right asymmetry GO:0061371 117 0.017
actomyosin structure organization GO:0031032 53 0.017
regulation of cell adhesion GO:0030155 15 0.016
cellular macromolecule biosynthetic process GO:0034645 224 0.016
regulation of extrinsic apoptotic signaling pathway GO:2001236 3 0.016
positive regulation of blood circulation GO:1903524 2 0.016
regulation of rna metabolic process GO:0051252 224 0.016
inorganic ion transmembrane transport GO:0098660 57 0.016
b cell activation GO:0042113 2 0.016
single organism cell adhesion GO:0098602 29 0.016
regulation of i kappab kinase nf kappab signaling GO:0043122 4 0.016
regulation of developmental process GO:0050793 247 0.016
biological adhesion GO:0022610 40 0.016
positive regulation of multi organism process GO:0043902 3 0.016
rna modification GO:0009451 2 0.016
myofibril assembly GO:0030239 48 0.015
regulation of cytoplasmic transport GO:1903649 4 0.015
regulation of cell projection organization GO:0031344 44 0.015
negative regulation of smoothened signaling pathway GO:0045879 6 0.015
transcription from rna polymerase ii promoter GO:0006366 80 0.015
amine metabolic process GO:0009308 2 0.015
positive regulation of lipid metabolic process GO:0045834 1 0.015
negative regulation of apoptotic process GO:0043066 55 0.015
cell projection assembly GO:0030031 64 0.015
response to organic substance GO:0010033 153 0.015
gastrulation GO:0007369 208 0.015
positive regulation of signaling GO:0023056 56 0.015
regulation of apoptotic process GO:0042981 98 0.015
positive regulation of transport GO:0051050 2 0.015
regulation of locomotion GO:0040012 55 0.015
positive regulation of leukocyte migration GO:0002687 2 0.015
regulation of hydrolase activity GO:0051336 28 0.015
locomotion GO:0040011 313 0.015
leukocyte mediated cytotoxicity GO:0001909 1 0.014
regulation of intracellular protein transport GO:0033157 3 0.014
regulation of sequestering of calcium ion GO:0051282 4 0.014
positive regulation of apoptotic signaling pathway GO:2001235 1 0.014
blood vessel development GO:0001568 246 0.014
regulation of gtpase activity GO:0043087 2 0.014
cell migration involved in gastrulation GO:0042074 79 0.014
stem cell differentiation GO:0048863 117 0.014
establishment of protein localization to organelle GO:0072594 4 0.014
mitotic dna damage checkpoint GO:0044773 4 0.014
meiosis i GO:0007127 1 0.013
positive regulation of signal transduction GO:0009967 56 0.013
skeletal system morphogenesis GO:0048705 102 0.013
neuron projection development GO:0031175 180 0.013
stem cell maintenance GO:0019827 4 0.013
macromolecule modification GO:0043412 111 0.013
protein targeting to nucleus GO:0044744 3 0.013
developmental programmed cell death GO:0010623 4 0.013
negative regulation of protein phosphorylation GO:0001933 4 0.013
regulation of autophagy GO:0010506 3 0.013
axis specification GO:0009798 43 0.013
negative regulation of signal transduction GO:0009968 94 0.013
mesenchymal cell development GO:0014031 78 0.013
cell substrate adherens junction assembly GO:0007045 1 0.013
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.013
somite development GO:0061053 96 0.013
ribonucleotide metabolic process GO:0009259 27 0.013
regulation of reproductive process GO:2000241 4 0.012
nucleobase containing compound metabolic process GO:0006139 274 0.012
positive regulation of extrinsic apoptotic signaling pathway GO:2001238 1 0.012
lipid metabolic process GO:0006629 52 0.012
negative regulation of cellular process GO:0048523 283 0.012
protein modification process GO:0036211 100 0.012
hindbrain development GO:0030902 91 0.012
cell adhesion GO:0007155 40 0.012
smooth muscle contraction GO:0006939 2 0.012
regulation of macromolecule biosynthetic process GO:0010556 225 0.012
mesenchyme development GO:0060485 127 0.012
regulation of cellular amino acid metabolic process GO:0006521 0 0.012
neural crest cell migration GO:0001755 42 0.012
macromolecule biosynthetic process GO:0009059 227 0.012
regulation of anatomical structure size GO:0090066 33 0.012
regulation of cell migration GO:0030334 40 0.012
morphogenesis of an epithelial sheet GO:0002011 49 0.012
protein localization to plasma membrane GO:0072659 1 0.012
gene expression GO:0010467 252 0.012
angiogenesis GO:0001525 158 0.012
blood vessel morphogenesis GO:0048514 216 0.012
regulation of synapse organization GO:0050807 3 0.012
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 1 0.012
response to virus GO:0009615 21 0.011
positive regulation of i kappab kinase nf kappab signaling GO:0043123 3 0.011
regulation of blood coagulation GO:0030193 1 0.011
cellular component assembly involved in morphogenesis GO:0010927 107 0.011
regulation of protein ubiquitination GO:0031396 3 0.011
cranial nerve development GO:0021545 42 0.011
carbohydrate derivative metabolic process GO:1901135 61 0.011
auditory receptor cell development GO:0060117 8 0.011
regulation of cell motility GO:2000145 46 0.011
positive regulation of nucleotide catabolic process GO:0030813 1 0.011
chromosome organization GO:0051276 31 0.011
cell junction maintenance GO:0034331 2 0.011
regulation of response to cytokine stimulus GO:0060759 3 0.011
phosphorus metabolic process GO:0006793 109 0.011
signal transduction in absence of ligand GO:0038034 1 0.011
negative regulation of extrinsic apoptotic signaling pathway GO:2001237 2 0.011
regulation of cytokine production GO:0001817 3 0.011
small gtpase mediated signal transduction GO:0007264 8 0.011
negative regulation of locomotion GO:0040013 18 0.011
regulation of protein modification by small protein conjugation or removal GO:1903320 3 0.011
generation of neurons GO:0048699 385 0.011
primary neural tube formation GO:0014020 1 0.011
protein secretion GO:0009306 1 0.011
positive regulation of jnk cascade GO:0046330 3 0.011
embryonic skeletal system development GO:0048706 97 0.011
respiratory system development GO:0060541 5 0.011
axis elongation GO:0003401 31 0.011
digestive tract development GO:0048565 265 0.011
cellular metal ion homeostasis GO:0006875 16 0.011
regulation of multicellular organismal process GO:0051239 277 0.011
regulation of catalytic activity GO:0050790 55 0.011
fin morphogenesis GO:0033334 53 0.010
regulation of blood vessel size GO:0050880 2 0.010
programmed cell death GO:0012501 119 0.010
regulation of developmental growth GO:0048638 38 0.010
female sex differentiation GO:0046660 4 0.010
tissue regeneration GO:0042246 74 0.010
organic substance biosynthetic process GO:1901576 289 0.010
developmental cell growth GO:0048588 52 0.010
leukocyte proliferation GO:0070661 1 0.010
purine ribonucleoside monophosphate catabolic process GO:0009169 4 0.010
hormone biosynthetic process GO:0042446 3 0.010
meiotic cell cycle process GO:1903046 3 0.010
thermosensory behavior GO:0040040 1 0.010

fmnl2b disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 0 0.021
inherited metabolic disorder DOID:655 0 0.021
disease of cellular proliferation DOID:14566 0 0.015
cancer DOID:162 0 0.015
gastrointestinal system cancer DOID:3119 0 0.015
organ system cancer DOID:0050686 0 0.015
disease of anatomical entity DOID:7 0 0.013
bone disease DOID:0080001 0 0.012
connective tissue disease DOID:65 0 0.012
musculoskeletal system disease DOID:17 0 0.012