Danio rerio

20 known processes

foxe3

forkhead box E3

foxe3 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.765
Human Zebrafish
cellular nitrogen compound metabolic process GO:0034641 290 0.691
Human Zebrafish
determination of left right symmetry GO:0007368 179 0.663
organic cyclic compound metabolic process GO:1901360 301 0.646
Human Zebrafish Mouse
lens development in camera type eye GO:0002088 22 0.610
rna biosynthetic process GO:0032774 181 0.590
Human Zebrafish
sensory organ development GO:0007423 393 0.587
camera type eye development GO:0043010 222 0.584
regulation of rna biosynthetic process GO:2001141 213 0.540
Human Zebrafish
rna metabolic process GO:0016070 219 0.524
Human Zebrafish
specification of symmetry GO:0009799 204 0.464
negative regulation of cellular process GO:0048523 283 0.452
Zebrafish
gland development GO:0048732 143 0.424
Human Zebrafish Mouse
regulation of biological quality GO:0065008 263 0.419
Zebrafish Mouse
eye development GO:0001654 277 0.369
regulation of transcription dna templated GO:0006355 213 0.358
Human Zebrafish
nucleobase containing compound metabolic process GO:0006139 274 0.347
Human Zebrafish
eye morphogenesis GO:0048592 144 0.345
negative regulation of biological process GO:0048519 304 0.344
Zebrafish
heterocycle metabolic process GO:0046483 290 0.342
Human Zebrafish
morphogenesis of an epithelium GO:0002009 333 0.338
Zebrafish Mouse
diencephalon development GO:0021536 58 0.311
nucleic acid metabolic process GO:0090304 244 0.309
Human Zebrafish
cellular nitrogen compound biosynthetic process GO:0044271 218 0.306
Human Zebrafish
signal transduction GO:0007165 455 0.301
regulation of primary metabolic process GO:0080090 311 0.297
Human Zebrafish
regulation of nitrogen compound metabolic process GO:0051171 251 0.294
Human Zebrafish
nucleobase containing compound biosynthetic process GO:0034654 205 0.293
Human Zebrafish
nucleic acid templated transcription GO:0097659 181 0.284
Human Zebrafish
regionalization GO:0003002 274 0.274
Zebrafish
response to drug GO:0042493 3 0.250
macromolecule biosynthetic process GO:0009059 227 0.246
Human Zebrafish
brain development GO:0007420 293 0.241
Zebrafish
response to external stimulus GO:0009605 264 0.231
regulation of multicellular organismal development GO:2000026 223 0.230
sensory organ morphogenesis GO:0090596 200 0.220
cellular macromolecule metabolic process GO:0044260 391 0.216
Human Zebrafish
pituitary gland development GO:0021983 16 0.213
cellular aromatic compound metabolic process GO:0006725 295 0.211
Human Zebrafish Mouse
positive regulation of cellular metabolic process GO:0031325 94 0.210
Human
regulation of nucleic acid templated transcription GO:1903506 213 0.204
Human Zebrafish
cellular macromolecule biosynthetic process GO:0034645 224 0.203
Human Zebrafish
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.186
Human Zebrafish
positive regulation of macromolecule metabolic process GO:0010604 93 0.186
Human
regulation of macromolecule biosynthetic process GO:0010556 225 0.168
Human Zebrafish
glycolipid metabolic process GO:0006664 8 0.166
gene expression GO:0010467 252 0.161
Human Zebrafish
determination of bilateral symmetry GO:0009855 204 0.158
regulation of rna metabolic process GO:0051252 224 0.152
Human Zebrafish
regulation of biosynthetic process GO:0009889 250 0.152
Human Zebrafish
response to wounding GO:0009611 116 0.151
transcription from rna polymerase ii promoter GO:0006366 80 0.151
Zebrafish
muscle cell differentiation GO:0042692 139 0.151
negative regulation of nucleobase containing compound metabolic process GO:0045934 59 0.150
Zebrafish
retina development in camera type eye GO:0060041 146 0.147
Zebrafish
astrocyte differentiation GO:0048708 1 0.144
heterocycle biosynthetic process GO:0018130 215 0.142
Human Zebrafish
digestive system development GO:0055123 289 0.141
Human
regulation of extrinsic apoptotic signaling pathway GO:2001236 3 0.141
neuron differentiation GO:0030182 353 0.139
Zebrafish
cell surface receptor signaling pathway GO:0007166 325 0.130
response to stress GO:0006950 263 0.130
transcription dna templated GO:0006351 181 0.126
Human Zebrafish
wound healing GO:0042060 90 0.125
organic cyclic compound biosynthetic process GO:1901362 223 0.122
Human Zebrafish
head development GO:0060322 303 0.119
Zebrafish
left right pattern formation GO:0060972 19 0.118
response to chemical GO:0042221 320 0.117
generation of neurons GO:0048699 385 0.117
Zebrafish
regulation of cellular metabolic process GO:0031323 320 0.115
Human Zebrafish
adenohypophysis development GO:0021984 15 0.115
biosynthetic process GO:0009058 294 0.112
Human Zebrafish
positive regulation of gene expression GO:0010628 71 0.104
Human
aromatic compound biosynthetic process GO:0019438 217 0.103
Human Zebrafish
regulation of locomotion GO:0040012 55 0.103
regulation of signaling GO:0023051 235 0.102
digestive tract development GO:0048565 265 0.101
Human
cellular response to prostaglandin stimulus GO:0071379 3 0.101
regulation of neural precursor cell proliferation GO:2000177 3 0.099
endocrine process GO:0050886 2 0.098
fin regeneration GO:0031101 51 0.092
regulation of gene expression GO:0010468 265 0.090
Human Zebrafish
developmental growth GO:0048589 166 0.087
cellular biosynthetic process GO:0044249 286 0.084
Human Zebrafish
gabaergic neuron differentiation GO:0097154 2 0.084
regulation of cell death GO:0010941 103 0.082
hepaticobiliary system development GO:0061008 98 0.082
cell fate commitment GO:0045165 99 0.081
Zebrafish
regeneration GO:0031099 91 0.081
single organism localization GO:1902578 225 0.079
central nervous system development GO:0007417 387 0.078
Zebrafish
positive regulation of macromolecule biosynthetic process GO:0010557 59 0.077
Human
response to amino acid GO:0043200 2 0.076
regulation of insulin like growth factor receptor signaling pathway GO:0043567 1 0.076
establishment of localization GO:0051234 244 0.076
regulation of cell differentiation GO:0045595 142 0.075
cellular response to endogenous stimulus GO:0071495 68 0.075
cilium assembly GO:0042384 58 0.074
tissue regeneration GO:0042246 74 0.074
homeostasis of number of cells GO:0048872 62 0.074
developmental pigmentation GO:0048066 48 0.073
Zebrafish
b cell differentiation GO:0030183 1 0.073
programmed cell death GO:0012501 119 0.072
positive regulation of epithelial cell differentiation GO:0030858 2 0.072
adherens junction organization GO:0034332 4 0.072
regulation of anatomical structure morphogenesis GO:0022603 130 0.069
apoptotic process GO:0006915 116 0.068
mesoderm development GO:0007498 88 0.067
Zebrafish
regulation of carbohydrate metabolic process GO:0006109 4 0.066
positive regulation of rna metabolic process GO:0051254 59 0.065
Human
muscle structure development GO:0061061 196 0.065
response to endogenous stimulus GO:0009719 83 0.064
embryonic organ morphogenesis GO:0048562 274 0.063
Zebrafish Mouse
regulation of metabolic process GO:0019222 359 0.062
Human Zebrafish
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.062
negative regulation of transcription dna templated GO:0045892 45 0.062
Zebrafish
cranial nerve development GO:0021545 42 0.061
Zebrafish
positive regulation of catabolic process GO:0009896 4 0.060
muscle organ development GO:0007517 101 0.060
cell morphogenesis involved in differentiation GO:0000904 195 0.059
regulation of reproductive process GO:2000241 4 0.059
endocrine system development GO:0035270 65 0.059
Human Mouse
cellular response to drug GO:0035690 1 0.057
lipid catabolic process GO:0016042 4 0.057
liver development GO:0001889 96 0.056
positive regulation of rna biosynthetic process GO:1902680 57 0.056
Human
negative regulation of cell death GO:0060548 60 0.056
i kappab kinase nf kappab signaling GO:0007249 4 0.055
embryo development ending in birth or egg hatching GO:0009792 271 0.055
Zebrafish
blood vessel development GO:0001568 246 0.054
Zebrafish
negative regulation of programmed cell death GO:0043069 58 0.054
positive regulation of metabolic process GO:0009893 108 0.053
Human
neuroblast proliferation GO:0007405 2 0.053
regulation of signal transduction GO:0009966 225 0.053
regulation of response to stimulus GO:0048583 269 0.052
endoderm development GO:0007492 49 0.052
Zebrafish
response to abiotic stimulus GO:0009628 122 0.052
cellular response to organic substance GO:0071310 105 0.051
neuroblast differentiation GO:0014016 1 0.051
positive regulation of biosynthetic process GO:0009891 68 0.051
Human
lipid metabolic process GO:0006629 52 0.051
negative regulation of macromolecule biosynthetic process GO:0010558 48 0.051
Zebrafish
b cell activation GO:0042113 2 0.051
nitrogen compound metabolic process GO:0006807 319 0.050
Human Zebrafish Mouse
negative regulation of sequestering of calcium ion GO:0051283 4 0.050
positive regulation of lipid metabolic process GO:0045834 1 0.050
auditory receptor cell fate commitment GO:0009912 4 0.048
positive regulation of neural precursor cell proliferation GO:2000179 1 0.048
lymphocyte mediated immunity GO:0002449 5 0.048
organic substance biosynthetic process GO:1901576 289 0.047
Human Zebrafish
negative regulation of apoptotic process GO:0043066 55 0.047
chemotaxis GO:0006935 104 0.047
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.046
Human
epiboly GO:0090504 41 0.046
negative regulation of chromosome organization GO:2001251 1 0.046
cell morphogenesis GO:0000902 289 0.045
cellular modified amino acid metabolic process GO:0006575 3 0.045
Mouse
blood vessel morphogenesis GO:0048514 216 0.045
positive regulation of cell cycle GO:0045787 3 0.044
regulation of hormone levels GO:0010817 21 0.044
Mouse
immune system process GO:0002376 241 0.043
Human
stem cell division GO:0017145 1 0.043
transport GO:0006810 220 0.043
growth GO:0040007 174 0.043
cellular response to hormone stimulus GO:0032870 39 0.042
negative regulation of hydrolase activity GO:0051346 10 0.042
muscle cell development GO:0055001 115 0.042
regulation of macromolecule metabolic process GO:0060255 317 0.042
Human Zebrafish
regulation of cellular carbohydrate metabolic process GO:0010675 4 0.042
peptide metabolic process GO:0006518 1 0.042
response to transition metal nanoparticle GO:1990267 28 0.041
multicellular organism growth GO:0035264 4 0.041
neuron fate specification GO:0048665 20 0.041
neuron projection morphogenesis GO:0048812 161 0.041
leukocyte differentiation GO:0002521 25 0.040
positive regulation of chromosome organization GO:2001252 1 0.039
cell projection morphogenesis GO:0048858 244 0.039
protein secretion GO:0009306 1 0.039
protein localization to nucleus GO:0034504 3 0.039
positive regulation of chromatin modification GO:1903310 1 0.039
spinal cord motor neuron cell fate specification GO:0021520 8 0.039
regulation of multicellular organism growth GO:0040014 4 0.038
tube morphogenesis GO:0035239 349 0.038
positive regulation of cellular catabolic process GO:0031331 3 0.038
cell death GO:0008219 121 0.037
lymph vessel morphogenesis GO:0036303 25 0.037
cell part morphogenesis GO:0032990 246 0.037
positive regulation of nervous system development GO:0051962 25 0.037
negative regulation of multicellular organismal process GO:0051241 69 0.037
embryonic skeletal system morphogenesis GO:0048704 93 0.037
Zebrafish
regulation of organ growth GO:0046620 3 0.037
cellular component movement GO:0006928 335 0.037
Zebrafish Mouse
positive regulation of histone modification GO:0031058 1 0.036
regulation of multicellular organismal process GO:0051239 277 0.036
organonitrogen compound metabolic process GO:1901564 74 0.036
Mouse
embryonic eye morphogenesis GO:0048048 30 0.035
connective tissue development GO:0061448 99 0.035
Zebrafish
positive regulation of cellular process GO:0048522 201 0.035
Human Mouse Rat
sprouting angiogenesis GO:0002040 53 0.035
multicellular organismal metabolic process GO:0044236 2 0.034
epithelial cell differentiation GO:0030855 116 0.034
Zebrafish
regulation of programmed cell death GO:0043067 101 0.034
regulation of fatty acid metabolic process GO:0019217 1 0.034
specification of organ identity GO:0010092 2 0.033
cell substrate adhesion GO:0031589 4 0.033
regulation of transcription from rna polymerase ii promoter GO:0006357 114 0.033
endodermal cell differentiation GO:0035987 19 0.033
aging GO:0007568 2 0.032
adult behavior GO:0030534 2 0.032
cellular response to chemical stimulus GO:0070887 157 0.032
regulation of histone methylation GO:0031060 3 0.032
regulation of apoptotic process GO:0042981 98 0.032
negative regulation of stem cell differentiation GO:2000737 2 0.032
appendage development GO:0048736 80 0.032
Zebrafish
cellular component assembly GO:0022607 170 0.032
regulation of vascular permeability GO:0043114 5 0.031
Zebrafish
homeostatic process GO:0042592 142 0.031
Zebrafish
axon development GO:0061564 166 0.031
neuron fate commitment GO:0048663 26 0.031
regulation of developmental process GO:0050793 247 0.031
aorta morphogenesis GO:0035909 3 0.031
regulation of lipid catabolic process GO:0050994 2 0.031
glial cell migration GO:0008347 3 0.031
cellular lipid catabolic process GO:0044242 3 0.030
lens morphogenesis in camera type eye GO:0002089 7 0.030
humoral immune response mediated by circulating immunoglobulin GO:0002455 3 0.030
regulation of i kappab kinase nf kappab signaling GO:0043122 4 0.030
localization of cell GO:0051674 244 0.030
Zebrafish Mouse
immunoglobulin mediated immune response GO:0016064 3 0.030
cellular response to nutrient levels GO:0031669 2 0.030
nerve development GO:0021675 45 0.030
Zebrafish
muscle tissue development GO:0060537 110 0.029
protein import GO:0017038 3 0.029
regulation of blood vessel size GO:0050880 2 0.029
skeletal system development GO:0001501 181 0.029
Zebrafish
regulation of stem cell differentiation GO:2000736 4 0.029
neuron development GO:0048666 262 0.029
striated muscle cell development GO:0055002 108 0.028
determination of digestive tract left right asymmetry GO:0071907 10 0.028
response to radiation GO:0009314 51 0.028
striated muscle tissue development GO:0014706 110 0.028
autophagy GO:0006914 4 0.027
regulation of cell development GO:0060284 100 0.027
positive regulation of multicellular organismal process GO:0051240 52 0.027
embryonic organ development GO:0048568 381 0.027
Zebrafish Mouse
heart development GO:0007507 313 0.027
positive regulation of blood circulation GO:1903524 2 0.027
positive regulation of biological process GO:0048518 253 0.027
Human Mouse Rat
negative regulation of extrinsic apoptotic signaling pathway GO:2001237 2 0.027
response to metal ion GO:0010038 34 0.026
regulation of mrna processing GO:0050684 3 0.026
negative regulation of neural precursor cell proliferation GO:2000178 1 0.026
neuroblast fate commitment GO:0014017 1 0.026
central nervous system neuron differentiation GO:0021953 74 0.026
circulatory system process GO:0003013 87 0.026
Zebrafish
negative regulation of epithelial cell proliferation GO:0050680 1 0.026
pigmentation GO:0043473 85 0.026
Zebrafish
response to nutrient GO:0007584 3 0.026
regulation of neurogenesis GO:0050767 87 0.026
regulation of autophagy GO:0010506 3 0.025
negative regulation of cellular metabolic process GO:0031324 77 0.025
Zebrafish
b cell mediated immunity GO:0019724 3 0.025
neuronal stem cell maintenance GO:0097150 2 0.025
skeletal muscle tissue development GO:0007519 67 0.025
cell proliferation GO:0008283 80 0.025
Mouse Rat
appendage morphogenesis GO:0035107 56 0.025
Zebrafish
embryonic heart tube left right pattern formation GO:0060971 5 0.025
forebrain neuron fate commitment GO:0021877 1 0.025
single organism transport GO:0044765 206 0.025
hindbrain development GO:0030902 91 0.025
phagocytosis GO:0006909 3 0.024
ventral spinal cord development GO:0021517 35 0.024
axon regeneration GO:0031103 14 0.024
heterophilic cell cell adhesion via plasma membrane cell adhesion molecules GO:0007157 2 0.024
morphogenesis of an epithelial sheet GO:0002011 49 0.024
dna alkylation GO:0006305 8 0.024
blood circulation GO:0008015 87 0.024
Zebrafish
glucose homeostasis GO:0042593 1 0.024
response to organic substance GO:0010033 153 0.024
somite specification GO:0001757 12 0.024
small molecule metabolic process GO:0044281 77 0.023
Mouse
liposaccharide metabolic process GO:1903509 8 0.023
regulation of cell fate specification GO:0042659 20 0.023
regulation of gastrulation GO:0010470 24 0.023
regulation of skeletal muscle tissue development GO:0048641 4 0.023
hormone secretion GO:0046879 2 0.023
death GO:0016265 121 0.023
positive regulation of transport GO:0051050 2 0.023
ventral spinal cord interneuron differentiation GO:0021514 12 0.023
female gonad development GO:0008585 4 0.023
cellular carbohydrate metabolic process GO:0044262 4 0.023
inner ear receptor cell fate commitment GO:0060120 4 0.023
negative regulation of endopeptidase activity GO:0010951 10 0.023
negative regulation of rna metabolic process GO:0051253 48 0.022
Zebrafish
protein import into nucleus GO:0006606 3 0.022
carbohydrate homeostasis GO:0033500 1 0.022
maintenance of location GO:0051235 4 0.022
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 68 0.022
cellular response to decreased oxygen levels GO:0036294 1 0.022
cell projection organization GO:0030030 284 0.022
venous blood vessel morphogenesis GO:0048845 3 0.022
retina layer formation GO:0010842 24 0.022
pancreas development GO:0031016 84 0.022
negative regulation of signal transduction GO:0009968 94 0.022
cellular protein catabolic process GO:0044257 4 0.021
midbrain development GO:0030901 28 0.021
camera type eye morphogenesis GO:0048593 108 0.021
cellular response to xenobiotic stimulus GO:0071466 35 0.021
epithelial cell development GO:0002064 42 0.021
regulation of dna replication GO:0006275 3 0.021
muscle fiber development GO:0048747 52 0.021
positive regulation of dna metabolic process GO:0051054 1 0.021
heart morphogenesis GO:0003007 156 0.021
guanosine containing compound catabolic process GO:1901069 2 0.020
cellular response to radiation GO:0071478 4 0.020
convergent extension involved in organogenesis GO:0060029 10 0.020
regulation of sodium ion transport GO:0002028 2 0.020
forebrain development GO:0030900 96 0.020
positive regulation of i kappab kinase nf kappab signaling GO:0043123 3 0.020
regulation of endodermal cell fate specification GO:0042663 15 0.020
gtp catabolic process GO:0006184 2 0.020
cell cycle process GO:0022402 53 0.020
negative regulation of cellular catabolic process GO:0031330 3 0.019
regulation of purine nucleotide catabolic process GO:0033121 2 0.019
regulation of skeletal muscle fiber development GO:0048742 2 0.019
ectodermal placode development GO:0071696 37 0.019
Zebrafish
regulation of endodermal cell differentiation GO:1903224 15 0.019
catabolic process GO:0009056 32 0.019
negative regulation of histone modification GO:0031057 1 0.019
negative regulation of tor signaling GO:0032007 2 0.019
germ line stem cell maintenance GO:0030718 2 0.019
striated muscle cell differentiation GO:0051146 129 0.019
chordate embryonic development GO:0043009 271 0.019
Zebrafish
nuclear transport GO:0051169 4 0.019
immune effector process GO:0002252 23 0.019
lymph vessel development GO:0001945 27 0.019
cellular response to lipid GO:0071396 39 0.019
endoderm formation GO:0001706 29 0.018
response to decreased oxygen levels GO:0036293 25 0.018
negative regulation of catabolic process GO:0009895 3 0.018
carbohydrate biosynthetic process GO:0016051 1 0.018
aorta development GO:0035904 4 0.018
camera type eye photoreceptor cell differentiation GO:0060219 19 0.018
positive regulation of cell development GO:0010720 25 0.018
lipid storage GO:0019915 1 0.018
development of primary female sexual characteristics GO:0046545 4 0.017
cell activation GO:0001775 16 0.017
regulation of cell shape GO:0008360 1 0.017
neuron migration GO:0001764 22 0.017
dna modification GO:0006304 8 0.017
cilium morphogenesis GO:0060271 85 0.017
sympathetic nervous system development GO:0048485 3 0.017
Zebrafish
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 4 0.017
myotube differentiation GO:0014902 45 0.017
single organism metabolic process GO:0044710 217 0.017
Mouse
negative regulation of histone methylation GO:0031061 1 0.017
polyol metabolic process GO:0019751 1 0.017
cartilage development GO:0051216 96 0.017
Zebrafish
cellular amino acid metabolic process GO:0006520 7 0.016
Mouse
positive regulation of nucleic acid templated transcription GO:1903508 57 0.016
Human
melanocyte differentiation GO:0030318 26 0.016
Zebrafish
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.016
olfactory placode development GO:0071698 12 0.016
organelle organization GO:0006996 227 0.016
modification dependent macromolecule catabolic process GO:0043632 3 0.016
endothelial cell fate commitment GO:0060839 3 0.016
negative regulation of cellular macromolecule biosynthetic process GO:2000113 48 0.016
Zebrafish
regulation of metal ion transport GO:0010959 4 0.016
tissue migration GO:0090130 37 0.016
multi organism process GO:0051704 134 0.016
hormone transport GO:0009914 2 0.016
negative regulation of nucleic acid templated transcription GO:1903507 45 0.016
Zebrafish
head morphogenesis GO:0060323 8 0.016
regulation of cellular protein catabolic process GO:1903362 1 0.015
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.015
hemopoiesis GO:0030097 183 0.015
inositol phosphate metabolic process GO:0043647 1 0.015
regulation of nervous system development GO:0051960 90 0.015
response to monosaccharide GO:0034284 3 0.015
negative regulation of gene expression GO:0010629 65 0.015
Zebrafish
regulation of dna templated transcription in response to stress GO:0043620 0 0.015
regulation of cell migration involved in sprouting angiogenesis GO:0090049 3 0.015
optic cup morphogenesis involved in camera type eye development GO:0002072 7 0.015
regulation of cytoplasmic transport GO:1903649 4 0.015
sequestering of metal ion GO:0051238 3 0.015
g protein coupled receptor signaling pathway GO:0007186 74 0.015
negative regulation of metabolic process GO:0009892 86 0.015
Zebrafish
regulation of carbohydrate biosynthetic process GO:0043255 1 0.015
triglyceride homeostasis GO:0070328 2 0.015
positive regulation of cell division GO:0051781 2 0.015
ovulation cycle process GO:0022602 2 0.015
regulation of establishment of protein localization GO:0070201 4 0.015
response to lipid GO:0033993 60 0.015
regulation of glucose import GO:0046324 1 0.015
post embryonic organ development GO:0048569 4 0.015
ectodermal placode morphogenesis GO:0071697 32 0.015
Zebrafish
cellular response to external stimulus GO:0071496 2 0.015
cellular localization GO:0051641 97 0.014
positive regulation of transcription dna templated GO:0045893 57 0.014
Human
regulation of heart growth GO:0060420 2 0.014
endodermal cell fate determination GO:0007493 2 0.014
cellular response to extracellular stimulus GO:0031668 2 0.014
positive regulation of cell activation GO:0050867 1 0.014
neuroepithelial cell differentiation GO:0060563 26 0.014
Zebrafish
cell fate specification GO:0001708 68 0.014
Zebrafish
macromolecular complex subunit organization GO:0043933 74 0.014
compound eye development GO:0048749 2 0.014
pigment cell differentiation GO:0050931 38 0.014
Zebrafish
negative regulation of protein phosphorylation GO:0001933 4 0.014
ventral spinal cord interneuron fate commitment GO:0060579 3 0.014
lymphangiogenesis GO:0001946 25 0.014
oligodendrocyte differentiation GO:0048709 23 0.014
Zebrafish
closure of optic fissure GO:0061386 6 0.014
morphogenesis of embryonic epithelium GO:0016331 30 0.014
response to glucose GO:0009749 3 0.014
regulation of hydrolase activity GO:0051336 28 0.014
regulation of phospholipase activity GO:0010517 2 0.014
neuroblast fate determination GO:0007400 1 0.014
regulation of cellular component movement GO:0051270 55 0.014
ventricular cardiac muscle tissue development GO:0003229 3 0.014
synaptic growth at neuromuscular junction GO:0051124 2 0.014
extrinsic apoptotic signaling pathway via death domain receptors GO:0008625 1 0.014
face development GO:0060324 8 0.014
olfactory placode morphogenesis GO:0071699 7 0.013
outflow tract morphogenesis GO:0003151 1 0.013
immune response GO:0006955 28 0.013
extrinsic apoptotic signaling pathway GO:0097191 3 0.013
dna catabolic process GO:0006308 1 0.013
epiboly involved in gastrulation with mouth forming second GO:0055113 35 0.013
cellular component morphogenesis GO:0032989 336 0.013
Zebrafish
leukocyte mediated immunity GO:0002443 6 0.013
neuron projection extension GO:1990138 45 0.013
photoreceptor cell fate specification GO:0043704 1 0.013
single organism biosynthetic process GO:0044711 71 0.013
regulation of neuron migration GO:2001222 2 0.013
neural retina development GO:0003407 49 0.013
response to nicotine GO:0035094 2 0.013
alcohol biosynthetic process GO:0046165 2 0.013
negative regulation of cell motility GO:2000146 17 0.013
lens fiber cell development GO:0070307 3 0.013
negative regulation of rna biosynthetic process GO:1902679 45 0.013
Zebrafish
gland morphogenesis GO:0022612 13 0.013
lateral inhibition GO:0046331 1 0.013
determination of heart left right asymmetry GO:0061371 117 0.013
polyol biosynthetic process GO:0046173 1 0.013
cell fate specification involved in pattern specification GO:0060573 3 0.013
neuromast development GO:0048884 46 0.013
determination of left right asymmetry in lateral mesoderm GO:0003140 20 0.013
dna methylation or demethylation GO:0044728 8 0.012
vascular process in circulatory system GO:0003018 6 0.012
Zebrafish
production of molecular mediator of immune response GO:0002440 2 0.012
response to hormone GO:0009725 48 0.012
protein targeting to nucleus GO:0044744 3 0.012
regulation of extrinsic apoptotic signaling pathway in absence of ligand GO:2001239 1 0.012
membrane hyperpolarization GO:0060081 1 0.012
regulation of inflammatory response GO:0050727 2 0.012
regulation of jun kinase activity GO:0043506 3 0.012
response to extracellular stimulus GO:0009991 10 0.012
sensory perception of mechanical stimulus GO:0050954 16 0.012
positive regulation of cellular carbohydrate metabolic process GO:0010676 1 0.012
positive regulation of cell differentiation GO:0045597 30 0.012
axonogenesis GO:0007409 152 0.012
cellular component disassembly GO:0022411 1 0.012
formation of primary germ layer GO:0001704 62 0.012
eye photoreceptor cell differentiation GO:0001754 45 0.012
response to other organism GO:0051707 97 0.012
macromolecule modification GO:0043412 111 0.012
gastrulation with mouth forming second GO:0001702 44 0.012
mitochondrion organization GO:0007005 4 0.012
cellular amide metabolic process GO:0043603 4 0.012
blood vessel endothelial cell migration GO:0043534 18 0.012
regulation of blood pressure GO:0008217 1 0.012
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 1 0.011
regulation of cell motility GO:2000145 46 0.011
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.011
response to oxygen levels GO:0070482 25 0.011
regulation of retina development in camera type eye GO:1902866 2 0.011
negative regulation of cellular component movement GO:0051271 18 0.011
cellular ketone metabolic process GO:0042180 11 0.011
establishment of localization in cell GO:0051649 77 0.011
oxoacid metabolic process GO:0043436 31 0.011
Mouse
negative regulation of cell migration GO:0030336 17 0.011
lymphocyte proliferation GO:0046651 1 0.011
regulation of gtp catabolic process GO:0033124 2 0.011
cell cycle g1 s phase transition GO:0044843 1 0.011
skeletal muscle organ development GO:0060538 78 0.011

foxe3 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.199
Human
cardiovascular system disease DOID:1287 0 0.199
artery disease DOID:0050828 0 0.031
vascular disease DOID:178 0 0.031
disease of metabolism DOID:0014667 0 0.031
bone disease DOID:0080001 0 0.031
musculoskeletal system disease DOID:17 0 0.031
connective tissue disease DOID:65 0 0.031
inherited metabolic disorder DOID:655 0 0.017
bone development disease DOID:0080006 0 0.015