Danio rerio

0 known processes

frzb

frizzled-related protein

(Aliases: sfrp3,ik:tdsubc_2e7,xx:tdsubc_2e7,cb291,id:ibd5075,fzb1,fzb-1)

frzb biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
optic placode formation GO:0001743 4 0.777
Zebrafish
cellular response to external stimulus GO:0071496 2 0.562
notochord development GO:0030903 54 0.542
embryonic organ development GO:0048568 381 0.491
Zebrafish Mouse
negative regulation of canonical wnt signaling pathway GO:0090090 21 0.458
Human Zebrafish Mouse Rat
determination of heart left right asymmetry GO:0061371 117 0.416
Zebrafish
embryonic eye morphogenesis GO:0048048 30 0.404
Zebrafish
response to external stimulus GO:0009605 264 0.365
regulation of response to stimulus GO:0048583 269 0.362
Human Zebrafish Mouse Rat
regulation of signal transduction GO:0009966 225 0.331
Human Zebrafish Mouse Rat
wnt signaling pathway GO:0016055 80 0.322
Human Zebrafish Mouse Rat Worm
cellular biosynthetic process GO:0044249 286 0.319
Human
negative regulation of response to stimulus GO:0048585 104 0.315
Human Zebrafish Mouse Rat
optic placode formation involved in camera type eye formation GO:0046619 3 0.315
Zebrafish
female gonad development GO:0008585 4 0.292
muscle structure development GO:0061061 196 0.290
regulation of wnt signaling pathway involved in digestive tract morphogenesis GO:2000056 2 0.289
signal transduction GO:0007165 455 0.289
Human Zebrafish Mouse Rat Worm
female sex differentiation GO:0046660 4 0.287
cell surface receptor signaling pathway GO:0007166 325 0.284
Human Zebrafish Mouse Rat Worm
skeletal muscle organ development GO:0060538 78 0.264
positive regulation of jnk cascade GO:0046330 3 0.258
negative regulation of developmental process GO:0051093 65 0.245
Mouse
single organism metabolic process GO:0044710 217 0.242
Human Rat
eye field cell fate commitment involved in camera type eye formation GO:0060898 3 0.228
Zebrafish
embryonic camera type eye morphogenesis GO:0048596 19 0.227
Zebrafish
multi organism process GO:0051704 134 0.224
Rat Worm
convergent extension involved in gastrulation GO:0060027 71 0.223
Zebrafish
immune system process GO:0002376 241 0.221
dorsal ventral pattern formation GO:0009953 125 0.220
Zebrafish
gastrulation GO:0007369 208 0.216
Zebrafish Worm
gland development GO:0048732 143 0.214
Zebrafish Mouse Rat
cartilage development GO:0051216 96 0.213
Mouse
brain development GO:0007420 293 0.210
Zebrafish
positive regulation of stress activated protein kinase signaling cascade GO:0070304 3 0.209
regionalization GO:0003002 274 0.208
Zebrafish
positive regulation of jun kinase activity GO:0043507 2 0.203
positive regulation of stress activated mapk cascade GO:0032874 3 0.201
hepatic duct development GO:0061011 2 0.199
cell fate specification GO:0001708 68 0.197
Worm
neural plate regionalization GO:0060897 10 0.193
Zebrafish
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 42 0.192
regulation of signaling GO:0023051 235 0.191
Human Zebrafish Mouse Rat
epithelial cell proliferation involved in liver morphogenesis GO:0072575 2 0.180
development of primary female sexual characteristics GO:0046545 4 0.179
ear morphogenesis GO:0042471 64 0.178
Mouse
enzyme linked receptor protein signaling pathway GO:0007167 106 0.175
intracellular signal transduction GO:0035556 85 0.175
Rat
death GO:0016265 121 0.172
Human
negative regulation of signaling GO:0023057 96 0.169
Human Zebrafish Mouse Rat
single organism transport GO:0044765 206 0.166
Human Worm
tube morphogenesis GO:0035239 349 0.158
Zebrafish Worm
negative regulation of wnt signaling pathway GO:0030178 30 0.157
Human Zebrafish Mouse Rat
immune system development GO:0002520 191 0.154
sensory organ development GO:0007423 393 0.153
Zebrafish Mouse
heart development GO:0007507 313 0.153
Zebrafish
axonogenesis GO:0007409 152 0.152
determination of bilateral symmetry GO:0009855 204 0.150
Zebrafish
cellular amine metabolic process GO:0044106 2 0.148
hepaticobiliary system development GO:0061008 98 0.146
Zebrafish Mouse
larval development GO:0002164 2 0.144
Worm
liver development GO:0001889 96 0.141
Zebrafish Mouse
generation of neurons GO:0048699 385 0.140
Zebrafish
neural plate pattern specification GO:0060896 12 0.135
Zebrafish
hematopoietic or lymphoid organ development GO:0048534 191 0.134
hepatocyte proliferation GO:0072574 2 0.129
negative regulation of cell communication GO:0010648 96 0.128
Human Zebrafish Mouse Rat
cellular response to nutrient levels GO:0031669 2 0.128
cellular response to extracellular stimulus GO:0031668 2 0.124
mesenchyme development GO:0060485 127 0.124
Mouse
negative regulation of signal transduction GO:0009968 94 0.122
Human Zebrafish Mouse Rat
response to stress GO:0006950 263 0.117
Zebrafish Rat
striated muscle cell differentiation GO:0051146 129 0.117
heart field specification GO:0003128 1 0.116
digestive tract morphogenesis GO:0048546 231 0.115
Zebrafish Worm
mesendoderm development GO:0048382 10 0.115
gene expression GO:0010467 252 0.112
Human
embryonic heart tube development GO:0035050 133 0.112
Zebrafish
protein metabolic process GO:0019538 183 0.111
smoothened signaling pathway GO:0007224 30 0.110
ectoderm development GO:0007398 9 0.110
wnt signaling pathway involved in somitogenesis GO:0090244 2 0.109
negative regulation of mitosis GO:0045839 3 0.106
negative regulation of anterior neural cell fate commitment of the neural plate by wnt signaling pathway GO:0022002 1 0.106
locomotion GO:0040011 313 0.105
Zebrafish Worm
homeostatic process GO:0042592 142 0.104
Human
eye development GO:0001654 277 0.103
Zebrafish
wnt signaling pathway involved in digestive tract morphogenesis GO:0044333 4 0.103
regulation of response to nutrient levels GO:0032107 1 0.102
blood vessel morphogenesis GO:0048514 216 0.098
muscle tissue development GO:0060537 110 0.096
mesoderm development GO:0007498 88 0.096
vasculature development GO:0001944 278 0.096
muscle cell differentiation GO:0042692 139 0.095
regulation of gene expression GO:0010468 265 0.095
Human
regulation of cell communication GO:0010646 232 0.095
Human Zebrafish Mouse Rat
regulation of cell death GO:0010941 103 0.094
Human
ear development GO:0043583 127 0.093
Mouse
regulation of wnt signaling pathway GO:0030111 53 0.092
Human Zebrafish Mouse Rat
transmembrane transport GO:0055085 120 0.092
cell motility GO:0048870 244 0.091
Zebrafish Worm
striated muscle tissue development GO:0014706 110 0.091
specification of symmetry GO:0009799 204 0.090
Zebrafish
angiogenesis GO:0001525 158 0.089
negative chemotaxis GO:0050919 1 0.089
calcium ion transport into cytosol GO:0060402 3 0.089
embryonic organ morphogenesis GO:0048562 274 0.089
Zebrafish Mouse
positive regulation of response to stimulus GO:0048584 80 0.088
Human
regulation of jun kinase activity GO:0043506 3 0.087
cellular amino acid metabolic process GO:0006520 7 0.087
regulation of cellular metabolic process GO:0031323 320 0.087
Human Rat
synaptic target recognition GO:0008039 1 0.085
response to organic substance GO:0010033 153 0.084
Rat
muscle organ development GO:0007517 101 0.084
somite development GO:0061053 96 0.083
Mouse
cell migration GO:0016477 237 0.083
Zebrafish Worm
extracellular structure organization GO:0043062 27 0.082
somitogenesis GO:0001756 87 0.082
anterior head development GO:0097065 2 0.082
cellular carbohydrate metabolic process GO:0044262 4 0.081
cellular response to starvation GO:0009267 1 0.079
localization of cell GO:0051674 244 0.078
Zebrafish Worm
regulation of canonical wnt signaling pathway GO:0060828 34 0.078
Human Zebrafish Mouse Rat
locomotor rhythm GO:0045475 3 0.078
regulation of epithelial cell proliferation GO:0050678 3 0.078
heart morphogenesis GO:0003007 156 0.076
Zebrafish
midbrain development GO:0030901 28 0.076
heart looping GO:0001947 94 0.076
Zebrafish
embryonic camera type eye development GO:0031076 29 0.075
Zebrafish
cellular protein catabolic process GO:0044257 4 0.075
skeletal system morphogenesis GO:0048705 102 0.074
digestive tract development GO:0048565 265 0.073
Zebrafish Worm
regulation of programmed cell death GO:0043067 101 0.072
Human
thrombocyte differentiation GO:0002574 4 0.071
negative regulation of protein phosphorylation GO:0001933 4 0.071
cellular component movement GO:0006928 335 0.070
Zebrafish Worm
regulation of response to extracellular stimulus GO:0032104 1 0.070
cell adhesion GO:0007155 40 0.069
neuron development GO:0048666 262 0.068
cellular response to chemical stimulus GO:0070887 157 0.068
organic cyclic compound biosynthetic process GO:1901362 223 0.067
Human
cell surface receptor signaling pathway involved in heart development GO:0061311 20 0.067
Zebrafish
positive regulation of biological process GO:0048518 253 0.066
Human
cell cycle arrest GO:0007050 1 0.066
negative regulation of fibroblast growth factor receptor signaling pathway GO:0040037 6 0.065
ectodermal placode development GO:0071696 37 0.065
Zebrafish
regulation of multicellular organismal development GO:2000026 223 0.065
Human Mouse
establishment of protein localization to organelle GO:0072594 4 0.065
multicellular organismal macromolecule metabolic process GO:0044259 2 0.065
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.063
response to other organism GO:0051707 97 0.063
dorsal convergence GO:0060030 14 0.063
peptidyl serine modification GO:0018209 2 0.063
positive regulation of rna biosynthetic process GO:1902680 57 0.063
non canonical wnt signaling pathway involved in heart development GO:0061341 2 0.062
Zebrafish
axon extension GO:0048675 45 0.062
ameboidal type cell migration GO:0001667 143 0.062
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.062
cell growth GO:0016049 57 0.062
Human
response to chemical GO:0042221 320 0.062
Rat
negative regulation of biological process GO:0048519 304 0.062
Human Zebrafish Mouse Rat
ectodermal placode morphogenesis GO:0071697 32 0.061
Zebrafish
epithelial tube morphogenesis GO:0060562 148 0.061
Zebrafish
establishment of localization GO:0051234 244 0.060
Human Worm
determination of dorsal ventral asymmetry GO:0048262 34 0.060
negative regulation of sequestering of calcium ion GO:0051283 4 0.060
cellular ketone metabolic process GO:0042180 11 0.060
regulation of macromolecule metabolic process GO:0060255 317 0.060
Human
regulation of cellular amine metabolic process GO:0033238 0 0.059
developmental growth GO:0048589 166 0.059
Zebrafish
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 50 0.058
regulation of reproductive process GO:2000241 4 0.058
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.057
negative regulation of nuclear division GO:0051784 3 0.057
regulation of cellular amino acid metabolic process GO:0006521 0 0.057
blood vessel development GO:0001568 246 0.056
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090101 22 0.056
rhythmic process GO:0048511 21 0.055
bmp signaling pathway GO:0030509 52 0.055
regulation of fibroblast growth factor receptor signaling pathway GO:0040036 20 0.055
axon guidance GO:0007411 86 0.055
nucleocytoplasmic transport GO:0006913 4 0.055
modification dependent protein catabolic process GO:0019941 3 0.055
programmed cell death GO:0012501 119 0.054
Human
otic vesicle development GO:0071599 42 0.054
ectodermal placode formation GO:0060788 26 0.054
Zebrafish
regulation of cellular ketone metabolic process GO:0010565 7 0.054
negative regulation of gastrulation GO:2000542 11 0.053
organic acid metabolic process GO:0006082 31 0.053
negative regulation of cellular process GO:0048523 283 0.053
Human Zebrafish Mouse Rat
collagen biosynthetic process GO:0032964 2 0.053
negative regulation of embryonic development GO:0045992 11 0.052
protein targeting to nucleus GO:0044744 3 0.052
pancreas development GO:0031016 84 0.052
Zebrafish
otic vesicle formation GO:0030916 27 0.051
collagen fibril organization GO:0030199 1 0.051
digestive system development GO:0055123 289 0.051
Zebrafish Worm
protein modification process GO:0036211 100 0.050
organic cyclic compound metabolic process GO:1901360 301 0.050
Human
cellular protein metabolic process GO:0044267 129 0.050
neural tube patterning GO:0021532 33 0.050
determination of left right symmetry GO:0007368 179 0.048
Zebrafish
negative regulation of kinase activity GO:0033673 4 0.048
modification dependent macromolecule catabolic process GO:0043632 3 0.048
oocyte maturation GO:0001556 4 0.048
ectoderm formation GO:0001705 2 0.047
urogenital system development GO:0001655 97 0.047
negative regulation of bmp signaling pathway GO:0030514 13 0.047
multicellular organism growth GO:0035264 4 0.046
positive regulation of nucleobase containing compound metabolic process GO:0045935 69 0.046
sensory perception GO:0007600 39 0.046
circadian rhythm GO:0007623 19 0.046
chondrocyte development GO:0002063 4 0.046
regulation of protein modification by small protein conjugation or removal GO:1903320 3 0.045
ovulation cycle GO:0042698 2 0.045
gall bladder development GO:0061010 1 0.045
ovarian follicle development GO:0001541 2 0.045
cellular nitrogen compound metabolic process GO:0034641 290 0.045
Human
negative regulation of epithelial cell proliferation GO:0050680 1 0.044
response to nutrient GO:0007584 3 0.044
mediolateral intercalation GO:0060031 3 0.044
fin development GO:0033333 77 0.044
spemann organizer formation GO:0060061 10 0.044
response to vitamin GO:0033273 3 0.044
regulation of cell cycle GO:0051726 52 0.043
Worm
carboxylic acid metabolic process GO:0019752 22 0.043
nuclear transport GO:0051169 4 0.043
tissue regeneration GO:0042246 74 0.043
Zebrafish
synaptic growth at neuromuscular junction GO:0051124 2 0.042
cellular macromolecule biosynthetic process GO:0034645 224 0.042
Human
central nervous system development GO:0007417 387 0.042
Zebrafish
cerebellum morphogenesis GO:0021587 10 0.042
amine metabolic process GO:0009308 2 0.042
g protein coupled receptor signaling pathway GO:0007186 74 0.041
response to wounding GO:0009611 116 0.041
Zebrafish
positive regulation of nucleic acid templated transcription GO:1903508 57 0.041
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.041
transport GO:0006810 220 0.041
Human Worm
extrinsic apoptotic signaling pathway GO:0097191 3 0.041
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.041
endoderm development GO:0007492 49 0.041
Worm
spinal cord development GO:0021510 46 0.041
Zebrafish
stem cell maintenance GO:0019827 4 0.040
organonitrogen compound metabolic process GO:1901564 74 0.040
cellular protein modification process GO:0006464 100 0.040
positive regulation of canonical wnt signaling pathway GO:0090263 4 0.039
Human
skeletal system development GO:0001501 181 0.039
Mouse
convergent extension GO:0060026 118 0.039
Zebrafish Mouse
camera type eye morphogenesis GO:0048593 108 0.039
Zebrafish
stem cell differentiation GO:0048863 117 0.039
Mouse
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.039
retinal ganglion cell axon guidance GO:0031290 35 0.039
cell migration involved in gastrulation GO:0042074 79 0.039
collagen metabolic process GO:0032963 2 0.038
lipid storage GO:0019915 1 0.038
ovulation cycle process GO:0022602 2 0.038
regulation of cytokine production GO:0001817 3 0.037
regulation of production of molecular mediator of immune response GO:0002700 1 0.037
regulation of organ morphogenesis GO:2000027 35 0.037
regulation of mitotic cell cycle GO:0007346 25 0.037
Worm
regulation of developmental growth GO:0048638 38 0.037
positive regulation of immune system process GO:0002684 17 0.037
peptidyl serine phosphorylation GO:0018105 1 0.037
embryonic skeletal system morphogenesis GO:0048704 93 0.037
mesenchymal cell development GO:0014031 78 0.036
neuron differentiation GO:0030182 353 0.036
Zebrafish
regulation of cellular response to growth factor stimulus GO:0090287 35 0.036
negative regulation of cell differentiation GO:0045596 46 0.036
Mouse
multicellular organismal metabolic process GO:0044236 2 0.036
cellular component morphogenesis GO:0032989 336 0.036
Zebrafish
positive regulation of map kinase activity GO:0043406 3 0.035
neurological system process GO:0050877 62 0.035
regulation of skeletal muscle tissue development GO:0048641 4 0.035
ubiquitin dependent protein catabolic process GO:0006511 3 0.035
regulation of sequestering of calcium ion GO:0051282 4 0.035
fibroblast growth factor receptor signaling pathway GO:0008543 22 0.035
phagocytosis GO:0006909 3 0.035
Worm
circulatory system process GO:0003013 87 0.035
negative regulation of mapk cascade GO:0043409 4 0.034
Rat
erk1 and erk2 cascade GO:0070371 4 0.034
skeletal muscle tissue development GO:0007519 67 0.034
innate immune response GO:0045087 13 0.034
forebrain neuron differentiation GO:0021879 14 0.034
Zebrafish
regulation of syncytium formation by plasma membrane fusion GO:0060142 2 0.034
positive regulation of cytokine production GO:0001819 2 0.034
phospholipase c activating g protein coupled receptor signaling pathway GO:0007200 2 0.034
cell morphogenesis GO:0000902 289 0.034
Zebrafish
biosynthetic process GO:0009058 294 0.034
Human
cellular component biogenesis GO:0044085 178 0.034
Zebrafish
positive regulation of peptidyl tyrosine phosphorylation GO:0050731 1 0.033
cellular response to fibroblast growth factor stimulus GO:0044344 22 0.033
regulation of establishment of protein localization GO:0070201 4 0.033
apoptotic process GO:0006915 116 0.033
Human
regeneration GO:0031099 91 0.033
Zebrafish
regulation of chromosome segregation GO:0051983 1 0.033
regulation of wnt signaling pathway involved in dorsal ventral axis specification GO:2000053 5 0.033
regulation of cellular biosynthetic process GO:0031326 245 0.033
Human
mononuclear cell proliferation GO:0032943 1 0.033
protein complex subunit organization GO:0071822 46 0.032
Worm
single organism cellular localization GO:1902580 46 0.032
Worm
non canonical wnt signaling pathway GO:0035567 13 0.032
Zebrafish Worm
ossification GO:0001503 23 0.032
negative regulation of leukocyte differentiation GO:1902106 1 0.031
morphogenesis of an epithelium GO:0002009 333 0.031
Zebrafish Mouse
protein import into nucleus GO:0006606 3 0.031
leukocyte proliferation GO:0070661 1 0.031
positive regulation of cell communication GO:0010647 56 0.031
Human
neural tube development GO:0021915 62 0.031
single organism behavior GO:0044708 24 0.031
aging GO:0007568 2 0.031
somatic stem cell maintenance GO:0035019 1 0.031
negative regulation of endodermal cell differentiation GO:1903225 8 0.031
regulation of protein transport GO:0051223 3 0.030
organic substance biosynthetic process GO:1901576 289 0.030
Human
response to lipid GO:0033993 60 0.030
Rat
regulation of cellular protein metabolic process GO:0032268 52 0.030
regulation of cell differentiation GO:0045595 142 0.030
Human Mouse
regulation of striated muscle contraction GO:0006942 2 0.030
tissue remodeling GO:0048771 4 0.030
Rat
single organism organelle organization GO:1902589 199 0.030
Zebrafish Worm
epithelium regeneration GO:1990399 14 0.030
Zebrafish
positive regulation of apoptotic process GO:0043065 29 0.030
Human
cilium morphogenesis GO:0060271 85 0.029
Zebrafish
ion transmembrane transport GO:0034220 91 0.029
extrinsic apoptotic signaling pathway in absence of ligand GO:0097192 1 0.029
regulation of mapk cascade GO:0043408 14 0.029
Rat
regulation of immune response GO:0050776 14 0.029
cellular response to prostaglandin stimulus GO:0071379 3 0.028
negative regulation of cell cycle GO:0045786 14 0.028
embryonic digestive tract development GO:0048566 4 0.028
negative regulation of cell death GO:0060548 60 0.028
regulation of muscle contraction GO:0006937 3 0.028
adherens junction organization GO:0034332 4 0.028
regulation of nitrogen compound metabolic process GO:0051171 251 0.028
Human
canonical wnt signaling pathway GO:0060070 48 0.028
Human Zebrafish Mouse Rat
heart process GO:0003015 71 0.028
erythrocyte homeostasis GO:0034101 55 0.027
cell projection assembly GO:0030031 64 0.027
Zebrafish
neural plate anterior posterior regionalization GO:0021999 8 0.027
wound healing GO:0042060 90 0.027
Zebrafish
regulation of apoptotic process GO:0042981 98 0.027
Human
phosphorylation GO:0016310 69 0.027
Rat
neuron projection morphogenesis GO:0048812 161 0.027
embryonic skeletal joint morphogenesis GO:0060272 3 0.027
forebrain development GO:0030900 96 0.027
Zebrafish
immune response GO:0006955 28 0.027
maintenance of location GO:0051235 4 0.027
system process GO:0003008 185 0.027
regulation of heart morphogenesis GO:2000826 17 0.027
spinal cord anterior posterior patterning GO:0021512 1 0.027
regulation of protein metabolic process GO:0051246 56 0.027
germ line stem cell maintenance GO:0030718 2 0.026
regulation of intracellular protein transport GO:0033157 3 0.026
embryonic camera type eye formation GO:0060900 10 0.026
Zebrafish
lymphocyte proliferation GO:0046651 1 0.026
negative regulation of cellular catabolic process GO:0031330 3 0.026
regulation of intracellular signal transduction GO:1902531 57 0.026
Rat
renal system development GO:0072001 94 0.026
regulation of endocrine process GO:0044060 2 0.026
cellular response to stress GO:0033554 62 0.026
Rat
regulation of catalytic activity GO:0050790 55 0.026
metencephalon development GO:0022037 27 0.026
Zebrafish
regulation of kinase activity GO:0043549 15 0.026
epithalamus development GO:0021538 10 0.026
sequestering of metal ion GO:0051238 3 0.026
single organismal cell cell adhesion GO:0016337 29 0.025
cellular response to endogenous stimulus GO:0071495 68 0.025
macromolecule localization GO:0033036 54 0.025
Worm
cellular component assembly GO:0022607 170 0.025
Zebrafish
hindbrain development GO:0030902 91 0.025
Zebrafish
chordate embryonic development GO:0043009 271 0.025
mapk cascade GO:0000165 18 0.025
Rat
negative regulation of anterior neural cell fate commitment of the neural plate GO:0022001 1 0.025
cellular aromatic compound metabolic process GO:0006725 295 0.025
Human
positive regulation of cytosolic calcium ion concentration GO:0007204 4 0.025
anterior posterior pattern specification GO:0009952 152 0.025
cell projection organization GO:0030030 284 0.025
Zebrafish
regulation of multicellular organism growth GO:0040014 4 0.025
sensory organ morphogenesis GO:0090596 200 0.025
Zebrafish Mouse
phosphorus metabolic process GO:0006793 109 0.025
Rat
diencephalon development GO:0021536 58 0.025
wnt signaling pathway involved in dorsal ventral axis specification GO:0044332 5 0.024
bmp signaling pathway involved in determination of left right symmetry GO:0003154 14 0.024
nitrogen compound metabolic process GO:0006807 319 0.024
Human
regulation of wnt signaling pathway calcium modulating pathway GO:0008591 3 0.024
nephron morphogenesis GO:0072028 2 0.024
regulation of protein catabolic process GO:0042176 1 0.024
cellular macromolecule metabolic process GO:0044260 391 0.024
Human
oxoacid metabolic process GO:0043436 31 0.024
phosphate containing compound metabolic process GO:0006796 108 0.024
Rat
segmentation GO:0035282 97 0.024
regulation of binding GO:0051098 3 0.024
extracellular matrix organization GO:0030198 27 0.024
establishment of localization in cell GO:0051649 77 0.024
Worm
cell fate commitment involved in pattern specification GO:0060581 6 0.024
Zebrafish
regulation of ectodermal cell fate specification GO:0042665 2 0.024
meiotic nuclear division GO:0007126 4 0.024
cell differentiation in hindbrain GO:0021533 5 0.023
myotube differentiation GO:0014902 45 0.023
nephron tubule morphogenesis GO:0072078 1 0.023
regulation of anatomical structure morphogenesis GO:0022603 130 0.023
notochord morphogenesis GO:0048570 17 0.023
response to biotic stimulus GO:0009607 97 0.023
oligodendrocyte differentiation GO:0048709 23 0.023
Zebrafish
intra s dna damage checkpoint GO:0031573 1 0.023
cartilage condensation GO:0001502 3 0.023
regulation of anterior head development GO:2000742 2 0.023
swim bladder development GO:0048794 19 0.023
Zebrafish
single organism localization GO:1902578 225 0.023
Human Worm
cell cycle g1 s phase transition GO:0044843 1 0.023
protein import GO:0017038 3 0.023
positive regulation of fibroblast growth factor receptor signaling pathway GO:0045743 9 0.022
inner ear development GO:0048839 126 0.022
Mouse
cell projection morphogenesis GO:0048858 244 0.022
Zebrafish
regulation of erk1 and erk2 cascade GO:0070372 4 0.022
nuclear import GO:0051170 3 0.022
fertilization GO:0009566 3 0.022
reactive oxygen species metabolic process GO:0072593 6 0.022
regulation of cytoplasmic transport GO:1903649 4 0.022
regulation of glial cell differentiation GO:0045685 4 0.022
response to abiotic stimulus GO:0009628 122 0.022
otic vesicle morphogenesis GO:0071600 34 0.022
morphogenesis of an epithelial fold GO:0060571 1 0.022
regulation of proteolysis GO:0030162 24 0.022
mitotic nuclear division GO:0007067 18 0.021
regulation of cellular protein catabolic process GO:1903362 1 0.021
endocrine process GO:0050886 2 0.021
heterocycle biosynthetic process GO:0018130 215 0.021
Human
negative regulation of muscle tissue development GO:1901862 2 0.021
carbohydrate homeostasis GO:0033500 1 0.021
mesoderm formation GO:0001707 43 0.021
regulation of tyrosine phosphorylation of stat protein GO:0042509 1 0.021
regulation of rna metabolic process GO:0051252 224 0.021
Human
androgen metabolic process GO:0008209 2 0.021
eye morphogenesis GO:0048592 144 0.021
Zebrafish
rostrocaudal neural tube patterning GO:0021903 29 0.021
tissue homeostasis GO:0001894 25 0.021
regulation of blood vessel size GO:0050880 2 0.020
head development GO:0060322 303 0.020
Zebrafish
stem cell development GO:0048864 82 0.020
regulation of cell proliferation GO:0042127 37 0.020
Human Rat
regulation of cell activation GO:0050865 1 0.020
positive regulation of cell division GO:0051781 2 0.020
negative regulation of stem cell differentiation GO:2000737 2 0.020
signal transduction in absence of ligand GO:0038034 1 0.020
cell death GO:0008219 121 0.020
Human
embryonic neurocranium morphogenesis GO:0048702 15 0.020
regulation of metabolic process GO:0019222 359 0.020
Human Rat
regulation of endothelial cell proliferation GO:0001936 1 0.020
signal transduction by phosphorylation GO:0023014 18 0.020
Rat
defense response to fungus GO:0050832 2 0.020
mesoderm morphogenesis GO:0048332 51 0.020
cell part morphogenesis GO:0032990 246 0.020
Zebrafish
cytoskeleton organization GO:0007010 96 0.020
Worm
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.020
striated muscle cell development GO:0055002 108 0.020
foregut morphogenesis GO:0007440 4 0.020
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 2 0.020
Human
energy reserve metabolic process GO:0006112 2 0.019
positive regulation of rna metabolic process GO:0051254 59 0.019
nucleobase containing compound metabolic process GO:0006139 274 0.019
Human
regulation of protein modification process GO:0031399 29 0.019
embryonic heart tube morphogenesis GO:0003143 108 0.019
Zebrafish
positive regulation of signaling GO:0023056 56 0.019
Human
macromolecular complex subunit organization GO:0043933 74 0.019
Worm
regulation of nuclear division GO:0051783 9 0.019
kupffer s vesicle development GO:0070121 50 0.019
limb bud formation GO:0060174 2 0.019
positive regulation of endothelial cell migration GO:0010595 2 0.019
regulation of transferase activity GO:0051338 16 0.019
apoptotic signaling pathway GO:0097190 23 0.019
epiboly GO:0090504 41 0.019
Zebrafish
activation of mapkkk activity GO:0000185 1 0.019
cell fate commitment GO:0045165 99 0.019
Zebrafish Worm
macroautophagy GO:0016236 1 0.019
b cell differentiation GO:0030183 1 0.019
tyrosine phosphorylation of stat protein GO:0007260 1 0.019
response to hormone GO:0009725 48 0.018
Rat
alpha amino acid metabolic process GO:1901605 3 0.018
organism emergence from protective structure GO:0071684 4 0.018
inner ear morphogenesis GO:0042472 63 0.018
Mouse
endocrine hormone secretion GO:0060986 2 0.018
regulation of cell development GO:0060284 100 0.018
Mouse
dorsal ventral neural tube patterning GO:0021904 1 0.018
axon development GO:0061564 166 0.018
secondary metabolic process GO:0019748 3 0.018
regulation of protein import into nucleus GO:0042306 2 0.018
regulation of immune system process GO:0002682 34 0.018
cell proliferation GO:0008283 80 0.018
Human Rat
negative regulation of protein complex assembly GO:0031333 1 0.018
regulation of system process GO:0044057 40 0.018
single organism nuclear import GO:1902593 3 0.018
odontogenesis of dentin containing tooth GO:0042475 1 0.018
cyclic nucleotide metabolic process GO:0009187 18 0.018

frzb disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.102
bone development disease DOID:0080006 0 0.018
bone disease DOID:0080001 0 0.018
musculoskeletal system disease DOID:17 0 0.018
connective tissue disease DOID:65 0 0.018