Danio rerio

14 known processes

gadd45aa

growth arrest and DNA-damage-inducible, alpha, a

(Aliases: zgc:77480,zgc:65993,MGC65993,gadd45al)

gadd45aa biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
response to cadmium ion GO:0046686 14 0.723
Zebrafish
apoptotic process GO:0006915 116 0.445
Human
p38mapk cascade GO:0038066 1 0.445
Human
signal transduction GO:0007165 455 0.440
Human Fly
positive regulation of biological process GO:0048518 253 0.438
Human
death GO:0016265 121 0.397
Human
response to transition metal nanoparticle GO:1990267 28 0.366
Zebrafish
positive regulation of cellular process GO:0048522 201 0.342
Human
programmed cell death GO:0012501 119 0.270
Human
mitochondrion organization GO:0007005 4 0.242
extrinsic apoptotic signaling pathway GO:0097191 3 0.233
response to metal ion GO:0010038 34 0.226
Zebrafish
regulation of extrinsic apoptotic signaling pathway GO:2001236 3 0.210
organic cyclic compound metabolic process GO:1901360 301 0.208
immune system process GO:0002376 241 0.201
post embryonic organ development GO:0048569 4 0.197
response to methylmercury GO:0051597 11 0.194
Zebrafish
regulation of metabolic process GO:0019222 359 0.189
Human Mouse
regulation of p38mapk cascade GO:1900744 1 0.182
Human
cell death GO:0008219 121 0.181
Human
nucleobase containing compound biosynthetic process GO:0034654 205 0.166
regulation of primary metabolic process GO:0080090 311 0.163
Human Mouse
nitrogen compound metabolic process GO:0006807 319 0.163
regulation of signal transduction GO:0009966 225 0.160
Human
response to external stimulus GO:0009605 264 0.152
Human
negative regulation of protein phosphorylation GO:0001933 4 0.147
Mouse
regulation of signaling GO:0023051 235 0.145
Human
modification dependent protein catabolic process GO:0019941 3 0.139
cellular aromatic compound metabolic process GO:0006725 295 0.138
gland development GO:0048732 143 0.136
response to chemical GO:0042221 320 0.135
Zebrafish
embryonic organ development GO:0048568 381 0.134
response to drug GO:0042493 3 0.132
regulation of apoptotic process GO:0042981 98 0.131
Human
negative regulation of cellular process GO:0048523 283 0.130
Mouse
regulation of programmed cell death GO:0043067 101 0.129
Human
immune system development GO:0002520 191 0.124
neuron differentiation GO:0030182 353 0.120
nucleic acid templated transcription GO:0097659 181 0.119
establishment of protein localization to organelle GO:0072594 4 0.118
response to inorganic substance GO:0010035 38 0.117
Zebrafish
extrinsic apoptotic signaling pathway via death domain receptors GO:0008625 1 0.115
response to temperature stimulus GO:0009266 15 0.114
regulation of macromolecule metabolic process GO:0060255 317 0.114
Human Mouse
heterocycle biosynthetic process GO:0018130 215 0.112
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.110
negative regulation of biological process GO:0048519 304 0.108
Mouse
cellular macromolecule metabolic process GO:0044260 391 0.104
Human Mouse
aging GO:0007568 2 0.102
heterocycle metabolic process GO:0046483 290 0.102
cellular nitrogen compound biosynthetic process GO:0044271 218 0.098
regulation of biological quality GO:0065008 263 0.098
negative regulation of kinase activity GO:0033673 4 0.097
Mouse
nucleobase containing compound metabolic process GO:0006139 274 0.095
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.094
cellular nitrogen compound metabolic process GO:0034641 290 0.093
regulation of cell communication GO:0010646 232 0.093
Human
nuclear import GO:0051170 3 0.092
regulation of metal ion transport GO:0010959 4 0.092
protein metabolic process GO:0019538 183 0.092
Human Mouse
regulation of cell death GO:0010941 103 0.092
Human
apoptotic process involved in development GO:1902742 2 0.089
sensory organ development GO:0007423 393 0.085
response to stress GO:0006950 263 0.084
Human Fly
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.084
cellular protein metabolic process GO:0044267 129 0.084
Human Mouse
hematopoietic or lymphoid organ development GO:0048534 191 0.083
activation of mapkkk activity GO:0000185 1 0.082
Human
positive regulation of extrinsic apoptotic signaling pathway GO:2001238 1 0.081
positive regulation of apoptotic signaling pathway GO:2001235 1 0.081
chordate embryonic development GO:0043009 271 0.080
Zebrafish
developmental programmed cell death GO:0010623 4 0.078
negative regulation of apoptotic process GO:0043066 55 0.077
macromolecule biosynthetic process GO:0009059 227 0.077
transcription dna templated GO:0006351 181 0.077
lipid storage GO:0019915 1 0.076
negative regulation of macromolecule metabolic process GO:0010605 76 0.076
Mouse
cellular response to dna damage stimulus GO:0006974 24 0.074
Human
positive regulation of response to stimulus GO:0048584 80 0.074
Human
cellular biosynthetic process GO:0044249 286 0.074
positive regulation of cellular catabolic process GO:0031331 3 0.073
g1 s transition of mitotic cell cycle GO:0000082 1 0.073
determination of left right symmetry GO:0007368 179 0.073
regulation of mitochondrion organization GO:0010821 1 0.072
cellular protein catabolic process GO:0044257 4 0.071
somitogenesis GO:0001756 87 0.071
Zebrafish
negative regulation of cellular metabolic process GO:0031324 77 0.071
Mouse
embryo development ending in birth or egg hatching GO:0009792 271 0.070
Zebrafish
single organism membrane fusion GO:0044801 2 0.069
protein localization to nucleus GO:0034504 3 0.068
regulation of autophagy GO:0010506 3 0.067
response to virus GO:0009615 21 0.066
extrinsic apoptotic signaling pathway in absence of ligand GO:0097192 1 0.066
membrane fusion GO:0061025 2 0.065
negative regulation of extrinsic apoptotic signaling pathway GO:2001237 2 0.065
organic cyclic compound biosynthetic process GO:1901362 223 0.065
central nervous system development GO:0007417 387 0.064
cell projection morphogenesis GO:0048858 244 0.064
regulation of transcription dna templated GO:0006355 213 0.064
positive regulation of jnk cascade GO:0046330 3 0.064
Human
signal transduction in absence of ligand GO:0038034 1 0.063
post embryonic morphogenesis GO:0009886 4 0.063
ubiquitin dependent protein catabolic process GO:0006511 3 0.062
cell cycle g1 s phase transition GO:0044843 1 0.062
transcription from rna polymerase ii promoter GO:0006366 80 0.061
cellular macromolecule biosynthetic process GO:0034645 224 0.061
myeloid cell homeostasis GO:0002262 56 0.061
response to external biotic stimulus GO:0043207 97 0.060
regulation of cellular biosynthetic process GO:0031326 245 0.059
positive regulation of catabolic process GO:0009896 4 0.059
reactive oxygen species metabolic process GO:0072593 6 0.059
Human
aromatic compound biosynthetic process GO:0019438 217 0.059
response to organic substance GO:0010033 153 0.058
Zebrafish
negative regulation of protein kinase activity GO:0006469 4 0.058
Mouse
regulation of response to stress GO:0080134 36 0.058
Human
maintenance of location GO:0051235 4 0.058
apoptotic process involved in morphogenesis GO:0060561 2 0.057
positive regulation of transport GO:0051050 2 0.056
response to other organism GO:0051707 97 0.056
regulation of rna biosynthetic process GO:2001141 213 0.055
response to nutrient GO:0007584 3 0.055
biosynthetic process GO:0009058 294 0.055
hemopoiesis GO:0030097 183 0.055
developmental growth GO:0048589 166 0.055
mitochondrial transport GO:0006839 2 0.054
cellular protein modification process GO:0006464 100 0.054
Human Mouse
regulation of immune system process GO:0002682 34 0.053
negative regulation of programmed cell death GO:0043069 58 0.052
organelle fusion GO:0048284 3 0.052
rna biosynthetic process GO:0032774 181 0.052
nucleocytoplasmic transport GO:0006913 4 0.051
cell fate specification GO:0001708 68 0.051
regulation of biosynthetic process GO:0009889 250 0.051
regulation of multicellular organism growth GO:0040014 4 0.051
regulation of macromolecule biosynthetic process GO:0010556 225 0.051
response to radiation GO:0009314 51 0.051
Human
organic acid metabolic process GO:0006082 31 0.050
neuron development GO:0048666 262 0.050
negative regulation of cellular macromolecule biosynthetic process GO:2000113 48 0.050
somite development GO:0061053 96 0.048
Zebrafish
regulation of organ growth GO:0046620 3 0.048
negative regulation of cell communication GO:0010648 96 0.048
protein targeting to nucleus GO:0044744 3 0.047
negative regulation of metabolic process GO:0009892 86 0.047
Mouse
regulation of transcription from rna polymerase ii promoter GO:0006357 114 0.046
regulation of reactive oxygen species metabolic process GO:2000377 2 0.044
Human
negative regulation of intracellular signal transduction GO:1902532 22 0.044
organic substance biosynthetic process GO:1901576 289 0.044
tube morphogenesis GO:0035239 349 0.043
cellular response to chemical stimulus GO:0070887 157 0.043
positive regulation of neuron apoptotic process GO:0043525 1 0.043
vasculature development GO:0001944 278 0.043
positive regulation of macromolecule metabolic process GO:0010604 93 0.042
Human
eye development GO:0001654 277 0.042
cell surface receptor signaling pathway GO:0007166 325 0.042
cell part morphogenesis GO:0032990 246 0.042
gene expression GO:0010467 252 0.041
secondary metabolic process GO:0019748 3 0.041
single organism nuclear import GO:1902593 3 0.041
alcohol biosynthetic process GO:0046165 2 0.041
negative regulation of cell death GO:0060548 60 0.041
proteasomal protein catabolic process GO:0010498 2 0.040
protein import into nucleus GO:0006606 3 0.040
carboxylic acid metabolic process GO:0019752 22 0.040
gamete generation GO:0007276 33 0.040
positive regulation of apoptotic process GO:0043065 29 0.040
Human
regulation of molecular function GO:0065009 70 0.040
Human Mouse
interspecies interaction between organisms GO:0044419 4 0.039
cellular component assembly involved in morphogenesis GO:0010927 107 0.039
regulation of nucleotide catabolic process GO:0030811 2 0.039
regulation of gene expression GO:0010468 265 0.039
regulation of stem cell differentiation GO:2000736 4 0.039
embryonic limb morphogenesis GO:0030326 2 0.039
establishment of localization GO:0051234 244 0.039
blood vessel development GO:0001568 246 0.039
response to biotic stimulus GO:0009607 97 0.039
modification dependent macromolecule catabolic process GO:0043632 3 0.038
modification of morphology or physiology of other organism involved in symbiotic interaction GO:0051817 4 0.038
single organism metabolic process GO:0044710 217 0.038
Human Fly
neuron projection morphogenesis GO:0048812 161 0.038
response to alkaloid GO:0043279 2 0.038
single organism organelle organization GO:1902589 199 0.038
Mouse
cellular response to stress GO:0033554 62 0.038
Human Fly
rna metabolic process GO:0016070 219 0.038
cell proliferation GO:0008283 80 0.038
cellular amide metabolic process GO:0043603 4 0.038
regulation of response to stimulus GO:0048583 269 0.038
Human Fly
negative regulation of nitrogen compound metabolic process GO:0051172 59 0.038
response to abiotic stimulus GO:0009628 122 0.037
Human
cellular component morphogenesis GO:0032989 336 0.037
cellular response to molecule of bacterial origin GO:0071219 3 0.036
response to lipid GO:0033993 60 0.036
response to glucocorticoid GO:0051384 1 0.036
regulation of protein import into nucleus GO:0042306 2 0.036
stem cell differentiation GO:0048863 117 0.035
positive regulation of stress activated protein kinase signaling cascade GO:0070304 3 0.035
Human
protein import GO:0017038 3 0.035
odontogenesis of dentin containing tooth GO:0042475 1 0.035
negative regulation of transcription dna templated GO:0045892 45 0.034
cell projection organization GO:0030030 284 0.034
regulation of nucleic acid templated transcription GO:1903506 213 0.034
regulation of protein complex assembly GO:0043254 3 0.034
apoptotic signaling pathway GO:0097190 23 0.034
positive regulation of cell cycle GO:0045787 3 0.034
nuclear transport GO:0051169 4 0.034
regulation of sodium ion transport GO:0002028 2 0.034
regulation of catalytic activity GO:0050790 55 0.033
Human Mouse
pigmentation GO:0043473 85 0.033
developmental pigmentation GO:0048066 48 0.033
multicellular organism growth GO:0035264 4 0.033
positive regulation of neuron death GO:1901216 1 0.033
regulation of rna metabolic process GO:0051252 224 0.033
macromolecule modification GO:0043412 111 0.032
Human Mouse
positive regulation of rna biosynthetic process GO:1902680 57 0.032
regulation of cellular metabolic process GO:0031323 320 0.032
Human Mouse
regulation of cellular protein catabolic process GO:1903362 1 0.032
cellular response to radiation GO:0071478 4 0.031
Human
establishment of protein localization to plasma membrane GO:0090002 1 0.031
cellular component biogenesis GO:0044085 178 0.031
regulation of multicellular organismal process GO:0051239 277 0.030
Fly
regulation of cytokine production GO:0001817 3 0.030
negative regulation of signal transduction GO:0009968 94 0.030
positive regulation of immune system process GO:0002684 17 0.030
cell cycle GO:0007049 93 0.030
Mouse
regulation of protein localization to nucleus GO:1900180 2 0.030
regulation of intracellular signal transduction GO:1902531 57 0.030
Human
cellular response to external stimulus GO:0071496 2 0.030
Human
intracellular signal transduction GO:0035556 85 0.030
Human Fly
metal ion transport GO:0030001 58 0.030
b cell activation GO:0042113 2 0.030
embryonic organ morphogenesis GO:0048562 274 0.029
positive regulation of gene expression GO:0010628 71 0.029
i kappab kinase nf kappab signaling GO:0007249 4 0.029
retina development in camera type eye GO:0060041 146 0.029
brain development GO:0007420 293 0.029
regulation of response to oxidative stress GO:1902882 2 0.029
regulation of cytoplasmic transport GO:1903649 4 0.029
regulation of heart growth GO:0060420 2 0.028
regulation of apoptotic signaling pathway GO:2001233 12 0.028
regeneration GO:0031099 91 0.028
positive regulation of stress activated mapk cascade GO:0032874 3 0.028
Human
regulation of cellular ketone metabolic process GO:0010565 7 0.028
hormone biosynthetic process GO:0042446 3 0.028
lipid metabolic process GO:0006629 52 0.027
nucleic acid metabolic process GO:0090304 244 0.027
response to bacterium GO:0009617 58 0.027
defense response GO:0006952 47 0.027
response to organic cyclic compound GO:0014070 51 0.027
purine nucleoside monophosphate catabolic process GO:0009128 4 0.027
axon development GO:0061564 166 0.027
camera type eye development GO:0043010 222 0.027
positive regulation of molecular function GO:0044093 33 0.027
Human
ear development GO:0043583 127 0.026
b cell differentiation GO:0030183 1 0.026
angiogenesis GO:0001525 158 0.026
regulation of cell activation GO:0050865 1 0.026
mesenchyme development GO:0060485 127 0.026
organonitrogen compound metabolic process GO:1901564 74 0.026
heart morphogenesis GO:0003007 156 0.026
heart development GO:0007507 313 0.026
morphogenesis of an epithelium GO:0002009 333 0.026
regulation of nitrogen compound metabolic process GO:0051171 251 0.026
mitochondrion morphogenesis GO:0070584 2 0.026
blood vessel morphogenesis GO:0048514 216 0.026
negative regulation of map kinase activity GO:0043407 2 0.026
multi organism process GO:0051704 134 0.026
Fly
oxoacid metabolic process GO:0043436 31 0.026
negative regulation of biosynthetic process GO:0009890 55 0.025
cellular component assembly GO:0022607 170 0.025
tissue remodeling GO:0048771 4 0.025
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.025
modification of morphology or physiology of other organism GO:0035821 4 0.025
epithelial tube morphogenesis GO:0060562 148 0.025
negative regulation of response to stimulus GO:0048585 104 0.025
protein localization to plasma membrane GO:0072659 1 0.025
post embryonic organ morphogenesis GO:0048563 1 0.025
cellular response to biotic stimulus GO:0071216 3 0.025
response to uv GO:0009411 3 0.025
single organism transport GO:0044765 206 0.025
negative regulation of protein serine threonine kinase activity GO:0071901 2 0.025
lymphocyte homeostasis GO:0002260 1 0.024
zymogen activation GO:0031638 3 0.024
regulation of cell differentiation GO:0045595 142 0.024
response to corticosteroid GO:0031960 1 0.024
regulation of protein transport GO:0051223 3 0.024
cell morphogenesis involved in differentiation GO:0000904 195 0.024
regulation of extrinsic apoptotic signaling pathway in absence of ligand GO:2001239 1 0.024
positive regulation of protein complex assembly GO:0031334 2 0.024
neuron projection development GO:0031175 180 0.024
positive regulation of developmental process GO:0051094 50 0.024
regulation of protein metabolic process GO:0051246 56 0.023
Human Mouse
peptide metabolic process GO:0006518 1 0.023
antimicrobial humoral response GO:0019730 2 0.023
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 1 0.023
regulation of purine nucleotide catabolic process GO:0033121 2 0.023
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 2 0.023
sensory organ morphogenesis GO:0090596 200 0.023
interaction with host GO:0051701 4 0.023
macromolecular complex subunit organization GO:0043933 74 0.023
regulation of developmental process GO:0050793 247 0.023
gtp metabolic process GO:0046039 4 0.023
negative regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043154 7 0.023
cellular aldehyde metabolic process GO:0006081 4 0.022
production of molecular mediator of immune response GO:0002440 2 0.022
axonogenesis GO:0007409 152 0.022
organelle organization GO:0006996 227 0.022
Mouse
peptidyl serine modification GO:0018209 2 0.022
cellular monovalent inorganic cation homeostasis GO:0030004 2 0.022
tissue regeneration GO:0042246 74 0.022
purine ribonucleoside monophosphate catabolic process GO:0009169 4 0.022
negative regulation of signaling GO:0023057 96 0.022
leukocyte proliferation GO:0070661 1 0.022
negative regulation of nucleobase containing compound metabolic process GO:0045934 59 0.022
intrinsic apoptotic signaling pathway in response to oxidative stress GO:0008631 2 0.021
negative regulation of intrinsic apoptotic signaling pathway GO:2001243 8 0.021
transport GO:0006810 220 0.021
generation of neurons GO:0048699 385 0.021
myeloid cell differentiation GO:0030099 86 0.021
positive regulation of multi organism process GO:0043902 3 0.021
catabolic process GO:0009056 32 0.021
reproductive process GO:0022414 40 0.021
Fly
cellular amine metabolic process GO:0044106 2 0.021
determination of bilateral symmetry GO:0009855 204 0.021
regulation of symbiosis encompassing mutualism through parasitism GO:0043903 1 0.021
peptidyl serine phosphorylation GO:0018105 1 0.021
specification of symmetry GO:0009799 204 0.021
osteoclast differentiation GO:0030316 1 0.021
larval development GO:0002164 2 0.021
response to light stimulus GO:0009416 46 0.021
killing of cells in other organism involved in symbiotic interaction GO:0051883 1 0.021
cellular sodium ion homeostasis GO:0006883 1 0.020
cell motility GO:0048870 244 0.020
positive regulation of cellular component biogenesis GO:0044089 3 0.020
membrane hyperpolarization GO:0060081 1 0.020
regulation of cell killing GO:0031341 2 0.020
fluid transport GO:0042044 17 0.020
regulation of endopeptidase activity GO:0052548 23 0.020
homeostatic process GO:0042592 142 0.020
mononuclear cell proliferation GO:0032943 1 0.020
regulation of establishment of protein localization GO:0070201 4 0.020
neuroblast proliferation GO:0007405 2 0.020
eye morphogenesis GO:0048592 144 0.019
response to vitamin GO:0033273 3 0.019
negative regulation of mitosis GO:0045839 3 0.019
negative regulation of cysteine type endopeptidase activity GO:2000117 8 0.019
cellular response to organic substance GO:0071310 105 0.019
fertilization GO:0009566 3 0.019
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.019
cellular amino acid metabolic process GO:0006520 7 0.019
microtubule organizing center organization GO:0031023 1 0.019
Mouse
fat soluble vitamin metabolic process GO:0006775 4 0.019
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.019
autophagy GO:0006914 4 0.019
cellular response to lipopolysaccharide GO:0071222 3 0.019
cellular component movement GO:0006928 335 0.019
small molecule metabolic process GO:0044281 77 0.019
phagocytosis GO:0006909 3 0.019
negative regulation of cellular biosynthetic process GO:0031327 55 0.018
positive regulation of cellular protein metabolic process GO:0032270 22 0.018
Human
negative regulation of apoptotic signaling pathway GO:2001234 10 0.018
regulation of i kappab kinase nf kappab signaling GO:0043122 4 0.018
skeletal system development GO:0001501 181 0.018
regulation of anatomical structure morphogenesis GO:0022603 130 0.018
growth GO:0040007 174 0.018
gtp catabolic process GO:0006184 2 0.018
negative regulation of catalytic activity GO:0043086 21 0.018
Mouse
regulation of binding GO:0051098 3 0.018
positive regulation of cellular biosynthetic process GO:0031328 68 0.018
cellular response to endogenous stimulus GO:0071495 68 0.018
multi organism cellular process GO:0044764 2 0.018
female sex differentiation GO:0046660 4 0.018
determination of heart left right asymmetry GO:0061371 117 0.018
pigment cell differentiation GO:0050931 38 0.018
protein complex assembly GO:0006461 30 0.017
positive regulation of metabolic process GO:0009893 108 0.017
Human
regulation of muscle contraction GO:0006937 3 0.017
peptide transport GO:0015833 1 0.017
leukocyte homeostasis GO:0001776 2 0.017
cellular response to hormone stimulus GO:0032870 39 0.017
cell substrate adhesion GO:0031589 4 0.017
positive regulation of gtp catabolic process GO:0033126 1 0.017
regulation of intracellular protein transport GO:0033157 3 0.017
cellular catabolic process GO:0044248 27 0.017
head development GO:0060322 303 0.017
positive regulation of endopeptidase activity GO:0010950 10 0.017
cellular lipid metabolic process GO:0044255 36 0.017
regulation of cellular protein metabolic process GO:0032268 52 0.017
Human Mouse
sensory perception of chemical stimulus GO:0007606 3 0.017
positive regulation of i kappab kinase nf kappab signaling GO:0043123 3 0.017
regulation of production of molecular mediator of immune response GO:0002700 1 0.017
negative regulation of nuclear division GO:0051784 3 0.017
positive regulation of dna metabolic process GO:0051054 1 0.017
epithelial cell differentiation GO:0030855 116 0.017
regulation of protein catabolic process GO:0042176 1 0.017
proteolysis GO:0006508 38 0.017
lymphocyte proliferation GO:0046651 1 0.017
negative regulation of rna metabolic process GO:0051253 48 0.017
regulation of cardiac muscle tissue development GO:0055024 1 0.016
symbiosis encompassing mutualism through parasitism GO:0044403 4 0.016
regulation of cell proliferation GO:0042127 37 0.016
response to unfolded protein GO:0006986 2 0.016
reactive nitrogen species metabolic process GO:2001057 0 0.016
homeostasis of number of cells GO:0048872 62 0.016
macromolecule catabolic process GO:0009057 15 0.016
amide biosynthetic process GO:0043604 1 0.016
centrosome organization GO:0051297 1 0.016
Mouse
positive regulation of cellular metabolic process GO:0031325 94 0.016
Human
positive regulation of nucleobase containing compound metabolic process GO:0045935 69 0.016
response to wounding GO:0009611 116 0.016
stem cell proliferation GO:0072089 4 0.016
cellular response to light stimulus GO:0071482 4 0.016
positive regulation of cell death GO:0010942 29 0.016
Human
vitamin metabolic process GO:0006766 11 0.016
cellular response to starvation GO:0009267 1 0.016
regulation of cell projection assembly GO:0060491 4 0.015
ribonucleoside monophosphate catabolic process GO:0009158 4 0.015
regulation of peptidase activity GO:0052547 23 0.015
actin filament based movement GO:0030048 1 0.015
collagen metabolic process GO:0032963 2 0.015
negative regulation of heart contraction GO:0045822 2 0.015
protein homooligomerization GO:0051260 3 0.015
positive regulation of biosynthetic process GO:0009891 68 0.015
cellular response to nutrient levels GO:0031669 2 0.015
regulation of cysteine type endopeptidase activity GO:2000116 21 0.015
positive regulation of immune effector process GO:0002699 3 0.015
single organism membrane organization GO:0044802 20 0.015
lymph vessel morphogenesis GO:0036303 25 0.015
response to antibiotic GO:0046677 1 0.015
negative regulation of gene expression GO:0010629 65 0.015
cell morphogenesis GO:0000902 289 0.015
atp catabolic process GO:0006200 4 0.015
defense response to bacterium GO:0042742 22 0.015
negative regulation of response to dna damage stimulus GO:2001021 3 0.015
digestive tract development GO:0048565 265 0.015
development of primary female sexual characteristics GO:0046545 4 0.015
hydrogen peroxide metabolic process GO:0042743 2 0.015
alpha amino acid metabolic process GO:1901605 3 0.015
guanosine containing compound catabolic process GO:1901069 2 0.015
cellular ketone metabolic process GO:0042180 11 0.015
macromolecular complex assembly GO:0065003 35 0.015
locomotor rhythm GO:0045475 3 0.015
endocrine system development GO:0035270 65 0.015
membrane organization GO:0061024 21 0.015
terpenoid metabolic process GO:0006721 15 0.015
modulation by virus of host morphology or physiology GO:0019048 1 0.014
heart looping GO:0001947 94 0.014
stem cell development GO:0048864 82 0.014
positive regulation of cell communication GO:0010647 56 0.014
Human
sodium ion transport GO:0006814 24 0.014
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 20 0.014
negative regulation of signal transduction in absence of ligand GO:1901099 1 0.014
protein phosphorylation GO:0006468 47 0.014
Human Mouse
positive regulation of inflammatory response GO:0050729 1 0.014
cell cycle arrest GO:0007050 1 0.014
regulation of nucleocytoplasmic transport GO:0046822 2 0.014
regulation of inflammatory response GO:0050727 2 0.014
viral process GO:0016032 1 0.014
regulation of cellular response to oxidative stress GO:1900407 2 0.014
negative regulation of multicellular organismal process GO:0051241 69 0.014
regulation of phosphorus metabolic process GO:0051174 43 0.014
Human Mouse
positive regulation of cell adhesion GO:0045785 1 0.014
membrane repolarization GO:0086009 2 0.014
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.014
protein modification process GO:0036211 100 0.013
Human Mouse
nitric oxide biosynthetic process GO:0006809 2 0.013
cellular amino acid biosynthetic process GO:0008652 2 0.013
compound eye development GO:0048749 2 0.013
response to topologically incorrect protein GO:0035966 2 0.013
regulation of dna catabolic process GO:1903624 1 0.013
muscle cell development GO:0055001 115 0.013
dorsal ventral pattern formation GO:0009953 125 0.013
system process GO:0003008 185 0.013
modification by symbiont of host morphology or physiology GO:0044003 4 0.013
phosphorylation GO:0016310 69 0.013
Human Mouse Fly
embryonic skeletal system morphogenesis GO:0048704 93 0.013
single organism intracellular transport GO:1902582 25 0.013
regulation of cellular ph GO:0030641 1 0.013
monovalent inorganic cation transport GO:0015672 42 0.013
cellular response to extracellular stimulus GO:0031668 2 0.013
female gonad development GO:0008585 4 0.013
intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress GO:0070059 3 0.013
embryonic heart tube morphogenesis GO:0003143 108 0.013
cellular response to hypoxia GO:0071456 1 0.013
protein complex subunit organization GO:0071822 46 0.013
regulation of protein targeting GO:1903533 2 0.013
glucocorticoid metabolic process GO:0008211 2 0.013
muscle structure development GO:0061061 196 0.013
regulation of developmental pigmentation GO:0048070 6 0.013
response to arsenic containing substance GO:0046685 5 0.013
superoxide metabolic process GO:0006801 2 0.013
nitric oxide metabolic process GO:0046209 2 0.012

gadd45aa disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.097
cardiovascular system disease DOID:1287 0 0.028
musculoskeletal system disease DOID:17 0 0.024
nervous system disease DOID:863 0 0.016
cancer DOID:162 0 0.015
disease of cellular proliferation DOID:14566 0 0.015
organ system cancer DOID:0050686 0 0.015
disease of metabolism DOID:0014667 0 0.014