Danio rerio

150 known processes

gata4

GATA-binding protein 4

(Aliases: gata)

gata4 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
embryonic organ morphogenesis GO:0048562 274 0.943
regionalization GO:0003002 274 0.932
Zebrafish Mouse Fly
heart morphogenesis GO:0003007 156 0.929
determination of heart left right asymmetry GO:0061371 117 0.890
eye development GO:0001654 277 0.852
generation of neurons GO:0048699 385 0.825
Zebrafish
regulation of response to stimulus GO:0048583 269 0.817
Fly
digestive tract development GO:0048565 265 0.803
Human Zebrafish Mouse
gland development GO:0048732 143 0.802
aromatic compound biosynthetic process GO:0019438 217 0.781
determination of bilateral symmetry GO:0009855 204 0.774
embryonic heart tube development GO:0035050 133 0.773
regulation of rna metabolic process GO:0051252 224 0.770
central nervous system development GO:0007417 387 0.751
Zebrafish
nucleic acid templated transcription GO:0097659 181 0.748
anterior posterior pattern specification GO:0009952 152 0.710
Mouse
segmentation GO:0035282 97 0.701
Fly
cell fate specification GO:0001708 68 0.700
digestive tract morphogenesis GO:0048546 231 0.695
Zebrafish Mouse
gastrulation GO:0007369 208 0.691
Zebrafish Mouse
regulation of biosynthetic process GO:0009889 250 0.682
transcription from rna polymerase ii promoter GO:0006366 80 0.664
tube morphogenesis GO:0035239 349 0.664
endocrine system development GO:0035270 65 0.663
Zebrafish
specification of symmetry GO:0009799 204 0.663
cardiac chamber formation GO:0003207 4 0.636
localization of cell GO:0051674 244 0.625
organic substance biosynthetic process GO:1901576 289 0.620
rna metabolic process GO:0016070 219 0.612
thyroid gland development GO:0030878 12 0.590
Zebrafish
chordate embryonic development GO:0043009 271 0.579
Zebrafish Mouse
regulation of multicellular organismal process GO:0051239 277 0.558
Zebrafish Mouse
regulation of heart morphogenesis GO:2000826 17 0.557
organic cyclic compound biosynthetic process GO:1901362 223 0.554
embryonic cranial skeleton morphogenesis GO:0048701 90 0.547
Zebrafish
camera type eye development GO:0043010 222 0.543
formation of primary germ layer GO:0001704 62 0.542
Zebrafish Mouse
digestive system development GO:0055123 289 0.542
Human Zebrafish Mouse
regulation of transcription from rna polymerase ii promoter GO:0006357 114 0.540
eye morphogenesis GO:0048592 144 0.535
regulation of nitrogen compound metabolic process GO:0051171 251 0.526
blood circulation GO:0008015 87 0.519
Fly
heterocycle biosynthetic process GO:0018130 215 0.518
immune system process GO:0002376 241 0.512
transcription dna templated GO:0006351 181 0.512
enzyme linked receptor protein signaling pathway GO:0007167 106 0.510
Zebrafish Mouse
ventral midline development GO:0007418 13 0.507
embryonic organ development GO:0048568 381 0.503
regulation of primary metabolic process GO:0080090 311 0.496
cell fate commitment GO:0045165 99 0.492
Mouse Fly
regulation of multicellular organismal development GO:2000026 223 0.485
Zebrafish Mouse
positive regulation of metabolic process GO:0009893 108 0.481
gliogenesis GO:0042063 45 0.474
regulation of transcription dna templated GO:0006355 213 0.473
positive regulation of macromolecule metabolic process GO:0010604 93 0.462
biosynthetic process GO:0009058 294 0.462
nucleobase containing compound biosynthetic process GO:0034654 205 0.459
signal transduction GO:0007165 455 0.450
Zebrafish Mouse
cellular component morphogenesis GO:0032989 336 0.427
cellular nitrogen compound biosynthetic process GO:0044271 218 0.419
hematopoietic or lymphoid organ development GO:0048534 191 0.417
cellular response to chemical stimulus GO:0070887 157 0.416
Zebrafish Mouse
heart development GO:0007507 313 0.415
regulation of cellular biosynthetic process GO:0031326 245 0.412
liver development GO:0001889 96 0.412
negative regulation of cellular process GO:0048523 283 0.407
Zebrafish Fly
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.403
gene expression GO:0010467 252 0.399
muscle structure development GO:0061061 196 0.389
heterocycle metabolic process GO:0046483 290 0.376
skeletal system morphogenesis GO:0048705 102 0.375
Zebrafish
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.369
macromolecule biosynthetic process GO:0009059 227 0.367
negative regulation of gene expression GO:0010629 65 0.366
Zebrafish Fly
fin development GO:0033333 77 0.365
negative regulation of transcription from rna polymerase ii promoter GO:0000122 16 0.364
Fly
ectodermal placode morphogenesis GO:0071697 32 0.363
Zebrafish
central nervous system neuron differentiation GO:0021953 74 0.358
Zebrafish
rna biosynthetic process GO:0032774 181 0.357
blood vessel development GO:0001568 246 0.356
Zebrafish Mouse
embryonic skeletal system morphogenesis GO:0048704 93 0.346
Zebrafish
hepaticobiliary system development GO:0061008 98 0.345
negative regulation of biological process GO:0048519 304 0.344
Zebrafish Fly
determination of left right symmetry GO:0007368 179 0.338
organ formation GO:0048645 17 0.336
negative regulation of nucleobase containing compound metabolic process GO:0045934 59 0.332
Fly
somitogenesis GO:0001756 87 0.332
regulation of nucleic acid templated transcription GO:1903506 213 0.328
cellular nitrogen compound metabolic process GO:0034641 290 0.322
cellular component movement GO:0006928 335 0.321
endocrine pancreas development GO:0031018 27 0.318
glial cell migration GO:0008347 3 0.313
floor plate formation GO:0021508 12 0.307
muscle cell differentiation GO:0042692 139 0.303
Zebrafish Mouse
negative regulation of rna biosynthetic process GO:1902679 45 0.296
Fly
cellular aromatic compound metabolic process GO:0006725 295 0.295
renal system development GO:0072001 94 0.294
Fly
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.289
floor plate development GO:0033504 15 0.288
ear development GO:0043583 127 0.287
Zebrafish
nucleic acid metabolic process GO:0090304 244 0.285
cell migration GO:0016477 237 0.282
muscle tissue development GO:0060537 110 0.282
neuron differentiation GO:0030182 353 0.276
Zebrafish
forebrain development GO:0030900 96 0.275
heart field specification GO:0003128 1 0.274
regulation of cell death GO:0010941 103 0.272
Zebrafish
negative regulation of transcription dna templated GO:0045892 45 0.268
Fly
response to external stimulus GO:0009605 264 0.267
Fly
heart process GO:0003015 71 0.266
Fly
positive regulation of biological process GO:0048518 253 0.260
mesoderm morphogenesis GO:0048332 51 0.258
regulation of cell differentiation GO:0045595 142 0.256
Zebrafish Mouse
somite development GO:0061053 96 0.256
inner ear development GO:0048839 126 0.254
Zebrafish
regulation of metabolic process GO:0019222 359 0.252
pancreas development GO:0031016 84 0.251
Zebrafish
positive regulation of rna metabolic process GO:0051254 59 0.248
erythrocyte development GO:0048821 24 0.248
Zebrafish
production of molecular mediator of immune response GO:0002440 2 0.245
Fly
locomotion GO:0040011 313 0.243
carbohydrate homeostasis GO:0033500 1 0.241
cellular response to growth factor stimulus GO:0071363 39 0.234
Zebrafish
dorsal ventral pattern formation GO:0009953 125 0.232
appendage morphogenesis GO:0035107 56 0.231
multi organism process GO:0051704 134 0.230
Mouse Fly
positive regulation of nucleobase containing compound metabolic process GO:0045935 69 0.228
mesoderm development GO:0007498 88 0.226
epithelial tube morphogenesis GO:0060562 148 0.225
immune system development GO:0002520 191 0.221
tissue regeneration GO:0042246 74 0.221
mesoderm formation GO:0001707 43 0.218
head development GO:0060322 303 0.218
cellular biosynthetic process GO:0044249 286 0.216
positive regulation of transcription dna templated GO:0045893 57 0.215
positive regulation of epithelial cell differentiation GO:0030858 2 0.211
cell motility GO:0048870 244 0.211
cardiac cell fate commitment GO:0060911 1 0.204
Fly
negative regulation of macromolecule metabolic process GO:0010605 76 0.203
Zebrafish Fly
pectoral fin development GO:0033339 50 0.203
fin morphogenesis GO:0033334 53 0.200
kidney development GO:0001822 92 0.198
cell cycle GO:0007049 93 0.193
positive regulation of biosynthetic process GO:0009891 68 0.191
regulation of signal transduction GO:0009966 225 0.190
embryonic eye morphogenesis GO:0048048 30 0.190
foregut morphogenesis GO:0007440 4 0.187
Zebrafish Mouse
specification of organ identity GO:0010092 2 0.187
response to stress GO:0006950 263 0.186
regulation of gene expression GO:0010468 265 0.184
sensory organ morphogenesis GO:0090596 200 0.184
Zebrafish
cellular macromolecule biosynthetic process GO:0034645 224 0.184
mesodermal cell differentiation GO:0048333 21 0.183
regulation of anatomical structure morphogenesis GO:0022603 130 0.182
Mouse
wound healing GO:0042060 90 0.182
morphogenesis of an epithelium GO:0002009 333 0.180
retina development in camera type eye GO:0060041 146 0.177
negative regulation of apoptotic process GO:0043066 55 0.170
Zebrafish
regulation of cellular metabolic process GO:0031323 320 0.169
appendage development GO:0048736 80 0.166
otic placode formation GO:0043049 23 0.165
Zebrafish
bmp signaling pathway GO:0030509 52 0.164
Mouse
embryonic heart tube morphogenesis GO:0003143 108 0.164
positive regulation of cellular process GO:0048522 201 0.163
developmental growth GO:0048589 166 0.162
peripheral nervous system development GO:0007422 55 0.159
regulation of cell migration GO:0030334 40 0.158
Zebrafish
cell surface receptor signaling pathway involved in heart development GO:0061311 20 0.157
floor plate morphogenesis GO:0033505 12 0.156
heart looping GO:0001947 94 0.156
regulation of apoptotic process GO:0042981 98 0.151
Zebrafish
negative regulation of cell death GO:0060548 60 0.151
Zebrafish
sensory organ development GO:0007423 393 0.151
Zebrafish Fly
outflow tract morphogenesis GO:0003151 1 0.147
cellular macromolecule metabolic process GO:0044260 391 0.147
small molecule biosynthetic process GO:0044283 16 0.146
ear morphogenesis GO:0042471 64 0.144
Zebrafish
regulation of neurogenesis GO:0050767 87 0.144
Zebrafish
embryonic camera type eye development GO:0031076 29 0.142
negative regulation of nitrogen compound metabolic process GO:0051172 59 0.141
Fly
embryonic skeletal system development GO:0048706 97 0.140
Zebrafish
regulation of localization GO:0032879 104 0.140
Zebrafish
negative regulation of cell fate commitment GO:0010454 13 0.140
regulation of organ growth GO:0046620 3 0.138
Mouse
embryonic digestive tract development GO:0048566 4 0.138
Mouse
regulation of cell proliferation GO:0042127 37 0.136
Zebrafish Mouse
regulation of hormone secretion GO:0046883 2 0.135
cardiogenic plate morphogenesis GO:0003142 1 0.134
inner ear morphogenesis GO:0042472 63 0.133
Zebrafish
urogenital system development GO:0001655 97 0.131
Fly
positive regulation of nucleic acid templated transcription GO:1903508 57 0.131
positive regulation of response to stimulus GO:0048584 80 0.129
regulation of rna biosynthetic process GO:2001141 213 0.128
regulation of production of molecular mediator of immune response GO:0002700 1 0.128
Fly
regulation of cell communication GO:0010646 232 0.127
positive regulation of cellular metabolic process GO:0031325 94 0.125
ameboidal type cell migration GO:0001667 143 0.124
diencephalon development GO:0021536 58 0.124
embryonic pattern specification GO:0009880 44 0.121
Fly
glial cell differentiation GO:0010001 42 0.119
neural tube development GO:0021915 62 0.118
hindbrain morphogenesis GO:0021575 22 0.118
organic cyclic compound metabolic process GO:1901360 301 0.117
oligodendrocyte differentiation GO:0048709 23 0.117
cardioblast migration to the midline involved in heart field formation GO:0060975 7 0.117
regulation of immune effector process GO:0002697 5 0.115
Fly
cell differentiation in spinal cord GO:0021515 40 0.113
Zebrafish
regulation of bmp signaling pathway involved in heart jogging GO:2000223 12 0.113
hormone secretion GO:0046879 2 0.113
mesenchyme development GO:0060485 127 0.111
Human Mouse
endothelial cell differentiation GO:0045446 20 0.109
regulation of macromolecule metabolic process GO:0060255 317 0.108
endocardium formation GO:0060214 1 0.105
regulation of cell development GO:0060284 100 0.105
Zebrafish
single organism metabolic process GO:0044710 217 0.102
Fly
response to biotic stimulus GO:0009607 97 0.101
Fly
regulation of embryonic development GO:0045995 47 0.100
homeostatic process GO:0042592 142 0.098
Zebrafish
single organism localization GO:1902578 225 0.097
regulation of stem cell differentiation GO:2000736 4 0.097
Mouse
brain development GO:0007420 293 0.096
stem cell development GO:0048864 82 0.096
response to growth factor GO:0070848 39 0.096
Zebrafish
cellular response to endogenous stimulus GO:0071495 68 0.096
Zebrafish Mouse
vasculature development GO:0001944 278 0.095
Zebrafish Mouse
regulation of cell fate specification GO:0042659 20 0.094
cellular response to nutrient levels GO:0031669 2 0.093
neuron projection morphogenesis GO:0048812 161 0.093
cellular response to extracellular stimulus GO:0031668 2 0.093
cardiac chamber morphogenesis GO:0003206 12 0.092
female gonad development GO:0008585 4 0.091
response to lipid GO:0033993 60 0.091
Mouse
lateral line system development GO:0048925 76 0.091
gall bladder development GO:0061010 1 0.090
protein metabolic process GO:0019538 183 0.089
nitrogen compound metabolic process GO:0006807 319 0.089
development of primary female sexual characteristics GO:0046545 4 0.089
negative regulation of nucleic acid templated transcription GO:1903507 45 0.088
Fly
cell projection organization GO:0030030 284 0.088
cell surface receptor signaling pathway GO:0007166 325 0.087
Zebrafish Mouse
response to other organism GO:0051707 97 0.087
Fly
endoderm development GO:0007492 49 0.086
Zebrafish Mouse
regulation of signaling GO:0023051 235 0.086
death GO:0016265 121 0.085
Zebrafish
hematopoietic progenitor cell differentiation GO:0002244 23 0.085
positive regulation of multicellular organismal process GO:0051240 52 0.082
Zebrafish Mouse
cardioblast migration GO:0003260 7 0.082
female sex differentiation GO:0046660 4 0.079
regeneration GO:0031099 91 0.078
gastrulation with mouth forming second GO:0001702 44 0.078
Mouse
oligodendrocyte cell fate specification GO:0021778 4 0.078
heart formation GO:0060914 13 0.077
negative regulation of cell communication GO:0010648 96 0.077
hemopoiesis GO:0030097 183 0.076
regulation of binding GO:0051098 3 0.076
positive regulation of signal transduction GO:0009967 56 0.075
regulation of programmed cell death GO:0043067 101 0.075
Zebrafish
glucose homeostasis GO:0042593 1 0.075
blood vessel morphogenesis GO:0048514 216 0.075
Zebrafish Mouse
maintenance of location GO:0051235 4 0.073
cardiac muscle tissue development GO:0048738 48 0.073
type b pancreatic cell development GO:0003323 4 0.073
cell morphogenesis involved in differentiation GO:0000904 195 0.072
organonitrogen compound metabolic process GO:1901564 74 0.072
Fly
spinal cord oligodendrocyte cell fate specification GO:0021530 2 0.071
regulation of nervous system development GO:0051960 90 0.069
Zebrafish
skeletal system development GO:0001501 181 0.067
Zebrafish
positive regulation of gene expression GO:0010628 71 0.067
negative regulation of multicellular organismal process GO:0051241 69 0.066
cellular response to external stimulus GO:0071496 2 0.066
response to oxygen containing compound GO:1901700 55 0.066
Mouse
response to endogenous stimulus GO:0009719 83 0.066
Zebrafish Mouse
programmed cell death GO:0012501 119 0.066
Zebrafish
negative regulation of stem cell differentiation GO:2000737 2 0.065
positive regulation of macromolecule biosynthetic process GO:0010557 59 0.065
kupffer s vesicle development GO:0070121 50 0.064
Zebrafish
response to wounding GO:0009611 116 0.064
positive regulation of transcription from rna polymerase ii promoter GO:0045944 22 0.064
nucleobase containing compound metabolic process GO:0006139 274 0.063
positive regulation of cellular biosynthetic process GO:0031328 68 0.063
positive regulation of neuron migration GO:2001224 2 0.063
Zebrafish
response to bacterium GO:0009617 58 0.063
positive regulation of signaling GO:0023056 56 0.062
regulation of response to stress GO:0080134 36 0.060
embryonic camera type eye morphogenesis GO:0048596 19 0.059
ectodermal placode formation GO:0060788 26 0.058
Zebrafish
growth GO:0040007 174 0.058
regulation of sequence specific dna binding transcription factor activity GO:0051090 9 0.058
negative regulation of developmental process GO:0051093 65 0.057
positive regulation of developmental process GO:0051094 50 0.056
Zebrafish Mouse
regulation of cardiac chamber morphogenesis GO:1901219 2 0.056
response to external biotic stimulus GO:0043207 97 0.056
Fly
negative regulation of signal transduction GO:0009968 94 0.055
negative regulation of gastrulation GO:2000542 11 0.054
cardiac conduction system development GO:0003161 1 0.054
cellular response to organic substance GO:0071310 105 0.054
Zebrafish Mouse
oligodendrocyte cell fate commitment GO:0021779 5 0.054
heart jogging GO:0003146 40 0.053
regulation of reproductive process GO:2000241 4 0.053
cardiac muscle cell differentiation GO:0055007 30 0.053
Zebrafish Mouse
negative regulation of programmed cell death GO:0043069 58 0.052
Zebrafish
axis specification GO:0009798 43 0.051
negative regulation of cellular biosynthetic process GO:0031327 55 0.051
Fly
ectodermal placode development GO:0071696 37 0.051
Zebrafish
bmp signaling pathway involved in determination of left right symmetry GO:0003154 14 0.051
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 50 0.051
regulation of cell morphogenesis GO:0022604 42 0.051
neuron development GO:0048666 262 0.050
peptide metabolic process GO:0006518 1 0.050
Fly
alcohol biosynthetic process GO:0046165 2 0.050
cellular amino acid metabolic process GO:0006520 7 0.050
striated muscle cell differentiation GO:0051146 129 0.049
Zebrafish Mouse
embryonic digestive tract morphogenesis GO:0048557 3 0.049
Mouse
cellular response to stress GO:0033554 62 0.048
bmp signaling pathway involved in heart jogging GO:0003303 14 0.048
organ growth GO:0035265 12 0.048
Mouse
negative regulation of cellular metabolic process GO:0031324 77 0.047
Fly
regulation of epithelial to mesenchymal transition GO:0010717 3 0.047
myeloid cell homeostasis GO:0002262 56 0.047
Zebrafish
lipid storage GO:0019915 1 0.047
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.047
negative regulation of response to stimulus GO:0048585 104 0.047
myeloid cell differentiation GO:0030099 86 0.046
wnt signaling pathway GO:0016055 80 0.046
Mouse
multicellular organism growth GO:0035264 4 0.046
regulation of macromolecule biosynthetic process GO:0010556 225 0.046
response to carbohydrate GO:0009743 3 0.045
posterior lateral line system development GO:0048915 46 0.045
lateral line development GO:0048882 66 0.045
regulation of locomotion GO:0040012 55 0.045
Zebrafish
stem cell differentiation GO:0048863 117 0.045
Mouse Fly
cardiac cell development GO:0055006 21 0.044
neural tube patterning GO:0021532 33 0.044
response to organic substance GO:0010033 153 0.044
Zebrafish Mouse
embryo development ending in birth or egg hatching GO:0009792 271 0.043
Zebrafish Mouse Fly
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 68 0.043
Mouse
regulation of molecular function GO:0065009 70 0.043
glial cell fate specification GO:0021780 4 0.043
regulation of cell cycle GO:0051726 52 0.043
bmp signaling pathway involved in heart development GO:0061312 15 0.043
organelle organization GO:0006996 227 0.042
lipid metabolic process GO:0006629 52 0.042
positive regulation of cell communication GO:0010647 56 0.042
cardiac muscle tissue morphogenesis GO:0055008 7 0.042
positive regulation of rna biosynthetic process GO:1902680 57 0.042
hormone transport GO:0009914 2 0.042
regulation of response to external stimulus GO:0032101 31 0.042
Fly
negative regulation of signaling GO:0023057 96 0.041
regulation of establishment of protein localization GO:0070201 4 0.041
regulation of protein metabolic process GO:0051246 56 0.041
cardiac muscle cell development GO:0055013 20 0.040
notochord development GO:0030903 54 0.040
heart growth GO:0060419 7 0.040
Mouse
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 42 0.040
Zebrafish
mesodermal cell migration GO:0008078 12 0.040
response to glucose GO:0009749 3 0.039
negative regulation of cell fate specification GO:0009996 11 0.039
astrocyte differentiation GO:0048708 1 0.039
myeloid leukocyte differentiation GO:0002573 15 0.039
Zebrafish
oxoacid metabolic process GO:0043436 31 0.038
sensory system development GO:0048880 76 0.038
muscle organ development GO:0007517 101 0.038
neuroepithelial cell differentiation GO:0060563 26 0.037
negative regulation of mesodermal cell fate specification GO:0042662 3 0.037
otic vesicle development GO:0071599 42 0.037
Zebrafish
determination of left right asymmetry in nervous system GO:0035545 4 0.037
positive regulation of transport GO:0051050 2 0.037
anterior posterior axis specification GO:0009948 20 0.036
positive regulation of cytokine production GO:0001819 2 0.036
Mouse
mesodermal cell fate commitment GO:0001710 14 0.036
regulation of transcription from rna polymerase ii promoter involved in heart development GO:1901213 15 0.036
neural plate regionalization GO:0060897 10 0.035
regulation of endodermal cell fate specification GO:0042663 15 0.035
cellular component assembly GO:0022607 170 0.034
myeloid cell development GO:0061515 32 0.034
Zebrafish
ventral spinal cord development GO:0021517 35 0.034
Zebrafish
positive regulation of cell cycle GO:0045787 3 0.034
response to fibroblast growth factor GO:0071774 22 0.034
Zebrafish
regulation of cellular response to growth factor stimulus GO:0090287 35 0.034
stem cell maintenance GO:0019827 4 0.034
artery development GO:0060840 22 0.034
Zebrafish
response to chemical GO:0042221 320 0.034
Human Zebrafish Mouse
embryonic hemopoiesis GO:0035162 53 0.033
Zebrafish
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090101 22 0.033
apoptotic process GO:0006915 116 0.033
Zebrafish
response to oxygen levels GO:0070482 25 0.033
mesodermal cell fate specification GO:0007501 12 0.033
smooth muscle contraction GO:0006939 2 0.032
chemical homeostasis GO:0048878 49 0.032
regulation of developmental process GO:0050793 247 0.032
Zebrafish Mouse
cellular component biogenesis GO:0044085 178 0.032
smoothened signaling pathway GO:0007224 30 0.032
cell morphogenesis GO:0000902 289 0.032
pharyngeal muscle development GO:0043282 4 0.032
regulation of biological quality GO:0065008 263 0.032
Zebrafish
optic placode formation involved in camera type eye formation GO:0046619 3 0.032
aorta morphogenesis GO:0035909 3 0.031
Zebrafish
dorsal ventral axis specification GO:0009950 14 0.031
negative regulation of cellular macromolecule biosynthetic process GO:2000113 48 0.030
Fly
positive regulation of locomotion GO:0040017 14 0.030
Zebrafish
neuron projection development GO:0031175 180 0.030
cellular response to starvation GO:0009267 1 0.030
epithelial cell fate commitment GO:0072148 11 0.030
Mouse
ventral spinal cord interneuron differentiation GO:0021514 12 0.029
Zebrafish
cell death GO:0008219 121 0.028
Zebrafish
striated muscle tissue development GO:0014706 110 0.028
regulation of skeletal muscle tissue development GO:0048641 4 0.028
olfactory bulb development GO:0021772 4 0.028
cell cell signaling involved in cell fate commitment GO:0045168 12 0.028
positive regulation of cell migration GO:0030335 11 0.028
Zebrafish
regulation of cardiac chamber formation GO:1901210 2 0.028
peptide transport GO:0015833 1 0.027
organic acid metabolic process GO:0006082 31 0.027
regulation of hormone levels GO:0010817 21 0.027
gland morphogenesis GO:0022612 13 0.027
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 2 0.026
negative regulation of macromolecule biosynthetic process GO:0010558 48 0.026
Fly
response to estrogen GO:0043627 27 0.026
Mouse
retina morphogenesis in camera type eye GO:0060042 79 0.025
developmental process involved in reproduction GO:0003006 27 0.025
Human Mouse
response to vitamin GO:0033273 3 0.025
cell part morphogenesis GO:0032990 246 0.025
embryonic neurocranium morphogenesis GO:0048702 15 0.025
Zebrafish
erythrocyte differentiation GO:0030218 54 0.025
Zebrafish
cellular amide metabolic process GO:0043603 4 0.025
Fly
response to monosaccharide GO:0034284 3 0.025
anterior commissure morphogenesis GO:0021960 3 0.025
phagocytosis GO:0006909 3 0.025
positive regulation of cellular carbohydrate metabolic process GO:0010676 1 0.024
post embryonic morphogenesis GO:0009886 4 0.024
Zebrafish
positive regulation of reproductive process GO:2000243 2 0.024
endothelium development GO:0003158 25 0.024
cell migration involved in heart formation GO:0060974 10 0.024
chemotaxis GO:0006935 104 0.024
intracellular signal transduction GO:0035556 85 0.024
response to ketone GO:1901654 1 0.024
single organism biosynthetic process GO:0044711 71 0.024
circulatory system process GO:0003013 87 0.024
Fly
cardiocyte differentiation GO:0035051 44 0.023
Zebrafish Mouse Fly
alcohol metabolic process GO:0006066 11 0.023
epithelial cell differentiation GO:0030855 116 0.023
Human Mouse
positive regulation of canonical wnt signaling pathway GO:0090263 4 0.023
zymogen activation GO:0031638 3 0.023
forebrain regionalization GO:0021871 4 0.023
regulation of cytokine production GO:0001817 3 0.023
Mouse
negative regulation of cell development GO:0010721 26 0.023
negative regulation of biosynthetic process GO:0009890 55 0.022
Fly
cell migration to the midline involved in heart development GO:0003318 12 0.022
cell cell signaling GO:0007267 52 0.022
Mouse
cell substrate adhesion GO:0031589 4 0.022
aorta development GO:0035904 4 0.022
Zebrafish
medial fin development GO:0033338 16 0.022
negative regulation of muscle tissue development GO:1901862 2 0.022
small molecule metabolic process GO:0044281 77 0.022
protein complex biogenesis GO:0070271 30 0.021
ovulation cycle GO:0042698 2 0.021
cell fate commitment involved in formation of primary germ layer GO:0060795 26 0.021
regulation of carbohydrate biosynthetic process GO:0043255 1 0.021
cellular protein catabolic process GO:0044257 4 0.021
hypothalamus development GO:0021854 14 0.021
endoderm formation GO:0001706 29 0.020
Zebrafish Mouse
cardioblast differentiation GO:0010002 9 0.020
Mouse Fly
spemann organizer formation GO:0060061 10 0.020
regulation of cell fate commitment GO:0010453 22 0.020
regulation of body fluid levels GO:0050878 16 0.020
cellular response to lipid GO:0071396 39 0.020
regulation of epithelial cell proliferation GO:0050678 3 0.020
positive regulation of response to external stimulus GO:0032103 9 0.020
regulation of multicellular organism growth GO:0040014 4 0.020
mononuclear cell proliferation GO:0032943 1 0.020
cellular component assembly involved in morphogenesis GO:0010927 107 0.019
regulation of behavior GO:0050795 24 0.019
endocardium morphogenesis GO:0003160 4 0.019
positive regulation of carbohydrate metabolic process GO:0045913 1 0.019
cardiac ventricle formation GO:0003211 1 0.019
positive regulation of molecular function GO:0044093 33 0.019
regulation of wnt signaling pathway GO:0030111 53 0.019
atrioventricular valve formation GO:0003190 3 0.019
Zebrafish Mouse
type b pancreatic cell differentiation GO:0003309 8 0.019
establishment of localization GO:0051234 244 0.019
lymphocyte proliferation GO:0046651 1 0.019
regulation of catalytic activity GO:0050790 55 0.019
regulation of proteolysis GO:0030162 24 0.018
cardiac atrium morphogenesis GO:0003209 2 0.018
Human Mouse
mesenchymal cell development GO:0014031 78 0.018
cell migration involved in gastrulation GO:0042074 79 0.018
regulation of protein transport GO:0051223 3 0.018

gata4 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.214
Human
disease of metabolism DOID:0014667 0 0.076
inherited metabolic disorder DOID:655 0 0.050
cardiovascular system disease DOID:1287 0 0.048
Human
musculoskeletal system disease DOID:17 0 0.021
pfeiffer syndrome DOID:14705 0 0.019
bone development disease DOID:0080006 0 0.019
bone disease DOID:0080001 0 0.019
acrocephalosyndactylia DOID:12960 0 0.019
dysostosis DOID:1934 0 0.019
connective tissue disease DOID:65 0 0.019
synostosis DOID:11971 0 0.019