Danio rerio

28 known processes

gcm2

glial cells missing homolog 2 (Drosophila)

(Aliases: GCMb,Gcm-2)

gcm2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
regulation of metabolic process GO:0019222 359 0.936
Fly
response to chemical GO:0042221 320 0.911
Mouse Fly
regulation of cell death GO:0010941 103 0.842
Mouse
response to alkaloid GO:0043279 2 0.802
head development GO:0060322 303 0.723
Fly
regulation of macromolecule metabolic process GO:0060255 317 0.708
Fly
regulation of primary metabolic process GO:0080090 311 0.705
Fly
chordate embryonic development GO:0043009 271 0.704
axon development GO:0061564 166 0.692
Fly
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.671
Fly
regulation of rna biosynthetic process GO:2001141 213 0.644
Fly
central nervous system development GO:0007417 387 0.639
response to abiotic stimulus GO:0009628 122 0.633
regulation of biological quality GO:0065008 263 0.614
cellular aromatic compound metabolic process GO:0006725 295 0.612
Fly
cellular component movement GO:0006928 335 0.610
Fly
brain development GO:0007420 293 0.594
cell morphogenesis involved in differentiation GO:0000904 195 0.582
Fly
otic vesicle formation GO:0030916 27 0.579
regulation of cellular metabolic process GO:0031323 320 0.579
Fly
gene expression GO:0010467 252 0.543
Fly
positive regulation of biosynthetic process GO:0009891 68 0.525
Fly
transport GO:0006810 220 0.513
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.513
Fly
nitrogen compound metabolic process GO:0006807 319 0.484
Fly
eye development GO:0001654 277 0.459
positive regulation of rna biosynthetic process GO:1902680 57 0.428
Fly
cellular nitrogen compound metabolic process GO:0034641 290 0.424
Fly
embryo development ending in birth or egg hatching GO:0009792 271 0.416
positive regulation of cellular process GO:0048522 201 0.415
Fly
organic acid catabolic process GO:0016054 3 0.411
negative regulation of biological process GO:0048519 304 0.401
Mouse Fly
multicellular organismal metabolic process GO:0044236 2 0.397
reactive nitrogen species metabolic process GO:2001057 0 0.393
camera type eye development GO:0043010 222 0.390
positive regulation of cellular biosynthetic process GO:0031328 68 0.388
Fly
regulation of epithelial cell proliferation GO:0050678 3 0.386
cellular biosynthetic process GO:0044249 286 0.384
Fly
ventral spinal cord development GO:0021517 35 0.382
cell part morphogenesis GO:0032990 246 0.370
Fly
heterocycle metabolic process GO:0046483 290 0.368
Fly
embryonic viscerocranium morphogenesis GO:0048703 52 0.365
anterior posterior pattern specification GO:0009952 152 0.363
larval development GO:0002164 2 0.360
g protein coupled receptor signaling pathway GO:0007186 74 0.359
gland development GO:0048732 143 0.356
branched chain amino acid metabolic process GO:0009081 1 0.351
otic vesicle development GO:0071599 42 0.351
aromatic compound biosynthetic process GO:0019438 217 0.337
Fly
glial cell migration GO:0008347 3 0.336
ear development GO:0043583 127 0.333
regulation of biosynthetic process GO:0009889 250 0.322
Fly
regulation of signaling GO:0023051 235 0.320
sympathetic nervous system development GO:0048485 3 0.318
neurotransmitter secretion GO:0007269 2 0.317
cranial nerve development GO:0021545 42 0.315
embryonic cranial skeleton morphogenesis GO:0048701 90 0.315
regulation of metal ion transport GO:0010959 4 0.314
otic vesicle morphogenesis GO:0071600 34 0.312
cell motility GO:0048870 244 0.304
organic cyclic compound metabolic process GO:1901360 301 0.296
Fly
muscle structure development GO:0061061 196 0.293
rna biosynthetic process GO:0032774 181 0.292
Fly
epidermis development GO:0008544 48 0.291
appendage morphogenesis GO:0035107 56 0.291
carbon dioxide transport GO:0015670 3 0.283
positive regulation of metabolic process GO:0009893 108 0.279
Fly
response to stress GO:0006950 263 0.274
regulation of transcription dna templated GO:0006355 213 0.271
Fly
neuron differentiation GO:0030182 353 0.266
Fly
nucleobase containing compound metabolic process GO:0006139 274 0.266
Fly
immune system process GO:0002376 241 0.260
Fly
negative regulation of cellular process GO:0048523 283 0.259
Mouse Fly
positive regulation of nucleobase containing compound metabolic process GO:0045935 69 0.255
Fly
regulation of developmental process GO:0050793 247 0.255
Fly
cellular localization GO:0051641 97 0.255
regulation of nucleic acid templated transcription GO:1903506 213 0.255
Fly
establishment of localization GO:0051234 244 0.253
cellular macromolecule metabolic process GO:0044260 391 0.251
Fly
organic cyclic compound biosynthetic process GO:1901362 223 0.248
Fly
localization of cell GO:0051674 244 0.245
adult behavior GO:0030534 2 0.241
cellular response to chemical stimulus GO:0070887 157 0.240
Mouse
gliogenesis GO:0042063 45 0.237
Fly
nucleic acid templated transcription GO:0097659 181 0.235
Fly
positive regulation of rna metabolic process GO:0051254 59 0.233
Fly
regulation of proteolysis GO:0030162 24 0.231
locomotion GO:0040011 313 0.220
Fly
negative regulation of biosynthetic process GO:0009890 55 0.215
taxis GO:0042330 109 0.213
Fly
axonogenesis GO:0007409 152 0.209
Fly
regulation of nitrogen compound metabolic process GO:0051171 251 0.209
Fly
sensory organ development GO:0007423 393 0.208
negative regulation of macromolecule biosynthetic process GO:0010558 48 0.206
morphogenesis of an epithelium GO:0002009 333 0.203
tissue remodeling GO:0048771 4 0.199
neural crest cell differentiation GO:0014033 72 0.197
superoxide metabolic process GO:0006801 2 0.194
regulation of vascular permeability GO:0043114 5 0.192
bicarbonate transport GO:0015701 4 0.190
hematopoietic or lymphoid organ development GO:0048534 191 0.189
Fly
embryonic organ morphogenesis GO:0048562 274 0.188
cellular response to organic substance GO:0071310 105 0.185
Mouse
embryonic skeletal system development GO:0048706 97 0.184
cell surface receptor signaling pathway GO:0007166 325 0.178
collagen metabolic process GO:0032963 2 0.178
positive regulation of inflammatory response GO:0050729 1 0.175
appendage development GO:0048736 80 0.168
neural crest cell migration GO:0001755 42 0.167
generation of neurons GO:0048699 385 0.167
Fly
otic placode formation GO:0043049 23 0.167
multicellular organismal macromolecule metabolic process GO:0044259 2 0.166
nucleic acid metabolic process GO:0090304 244 0.161
Fly
single organism metabolic process GO:0044710 217 0.156
autonomic nervous system development GO:0048483 19 0.156
regulation of cell communication GO:0010646 232 0.155
biosynthetic process GO:0009058 294 0.155
Fly
organonitrogen compound metabolic process GO:1901564 74 0.155
regulation of response to stimulus GO:0048583 269 0.152
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.151
Fly
response to wounding GO:0009611 116 0.149
nucleobase containing compound biosynthetic process GO:0034654 205 0.149
Fly
aging GO:0007568 2 0.149
neural crest cell development GO:0014032 62 0.145
circulatory system process GO:0003013 87 0.145
cellular component morphogenesis GO:0032989 336 0.145
Fly
single organism transport GO:0044765 206 0.142
sensory organ morphogenesis GO:0090596 200 0.141
positive regulation of cellular metabolic process GO:0031325 94 0.141
Fly
system process GO:0003008 185 0.138
reactive oxygen species biosynthetic process GO:1903409 1 0.137
cellular response to oxygen levels GO:0071453 1 0.137
cell migration GO:0016477 237 0.136
regulation of multicellular organism growth GO:0040014 4 0.136
positive regulation of nucleic acid templated transcription GO:1903508 57 0.135
Fly
regulation of cellular biosynthetic process GO:0031326 245 0.135
Fly
negative regulation of nitrogen compound metabolic process GO:0051172 59 0.134
central nervous system myelination GO:0022010 2 0.130
negative regulation of nucleic acid templated transcription GO:1903507 45 0.129
liver development GO:0001889 96 0.128
rho protein signal transduction GO:0007266 5 0.127
mesenchyme development GO:0060485 127 0.127
positive regulation of biological process GO:0048518 253 0.125
Fly
response to organic substance GO:0010033 153 0.123
Mouse
tissue homeostasis GO:0001894 25 0.122
transcription dna templated GO:0006351 181 0.122
Fly
regionalization GO:0003002 274 0.122
Fly
programmed cell death GO:0012501 119 0.121
Mouse
regulation of gene expression GO:0010468 265 0.121
Fly
single organism localization GO:1902578 225 0.120
epidermal cell differentiation GO:0009913 36 0.119
regulation of cellular extravasation GO:0002691 1 0.118
organic substance transport GO:0071702 58 0.118
spinal cord development GO:0021510 46 0.118
negative regulation of gene expression GO:0010629 65 0.117
regulation of inflammatory response GO:0050727 2 0.116
response to amino acid GO:0043200 2 0.115
cell projection morphogenesis GO:0048858 244 0.115
Fly
hormone transport GO:0009914 2 0.114
behavior GO:0007610 74 0.114
death GO:0016265 121 0.112
Mouse
response to lipid GO:0033993 60 0.111
neuron development GO:0048666 262 0.111
Fly
inner ear development GO:0048839 126 0.110
multicellular organismal homeostasis GO:0048871 29 0.110
response to oxygen containing compound GO:1901700 55 0.109
negative regulation of cell communication GO:0010648 96 0.108
cell morphogenesis GO:0000902 289 0.105
Fly
regulation of hormone secretion GO:0046883 2 0.105
regulation of transport GO:0051049 45 0.104
growth GO:0040007 174 0.103
digestive system development GO:0055123 289 0.101
cellular response to endogenous stimulus GO:0071495 68 0.100
regulation of localization GO:0032879 104 0.099
regulation of rna metabolic process GO:0051252 224 0.099
Fly
cellular response to decreased oxygen levels GO:0036294 1 0.098
negative regulation of cellular biosynthetic process GO:0031327 55 0.097
cell death GO:0008219 121 0.097
Mouse
ectodermal placode development GO:0071696 37 0.097
ectodermal placode formation GO:0060788 26 0.097
organic substance biosynthetic process GO:1901576 289 0.096
Fly
floor plate development GO:0033504 15 0.096
neural tube development GO:0021915 62 0.096
negative regulation of transcription dna templated GO:0045892 45 0.096
determination of bilateral symmetry GO:0009855 204 0.095
cellular catabolic process GO:0044248 27 0.095
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.095
Fly
extrinsic apoptotic signaling pathway GO:0097191 3 0.094
signal transduction GO:0007165 455 0.094
regulation of apoptotic process GO:0042981 98 0.093
Mouse
immune system development GO:0002520 191 0.093
Fly
homeostatic process GO:0042592 142 0.092
glial cell fate commitment GO:0021781 6 0.091
Fly
carbohydrate derivative metabolic process GO:1901135 61 0.090
positive regulation of programmed cell death GO:0043068 29 0.089
macromolecule biosynthetic process GO:0009059 227 0.088
Fly
homeostasis of number of cells GO:0048872 62 0.087
embryonic skeletal system morphogenesis GO:0048704 93 0.085
carboxylic acid catabolic process GO:0046395 3 0.084
regulation of ph GO:0006885 3 0.084
epithelial cell differentiation GO:0030855 116 0.083
nitric oxide metabolic process GO:0046209 2 0.083
eye morphogenesis GO:0048592 144 0.083
glial cell differentiation GO:0010001 42 0.081
Fly
embryonic limb morphogenesis GO:0030326 2 0.080
positive regulation of transcription from rna polymerase ii promoter GO:0045944 22 0.080
Fly
cellular response to nutrient levels GO:0031669 2 0.080
protein localization GO:0008104 40 0.079
regulation of blood vessel size GO:0050880 2 0.079
positive regulation of transcription dna templated GO:0045893 57 0.078
Fly
primary neural tube formation GO:0014020 1 0.078
positive regulation of catabolic process GO:0009896 4 0.077
lateral line nerve glial cell development GO:0048937 6 0.077
retina development in camera type eye GO:0060041 146 0.077
cell fate commitment GO:0045165 99 0.077
positive regulation of macromolecule biosynthetic process GO:0010557 59 0.076
Fly
neurological system process GO:0050877 62 0.076
hematopoietic stem cell differentiation GO:0060218 20 0.075
hormone secretion GO:0046879 2 0.075
gtp catabolic process GO:0006184 2 0.075
oligodendrocyte cell fate commitment GO:0021779 5 0.074
fin development GO:0033333 77 0.074
negative regulation of cell death GO:0060548 60 0.074
Mouse
hypotonic response GO:0006971 5 0.073
cellular response to lipid GO:0071396 39 0.073
leukocyte migration GO:0050900 15 0.073
cellular response to hypoxia GO:0071456 1 0.073
multi organism process GO:0051704 134 0.072
skeletal system development GO:0001501 181 0.072
negative regulation of response to stimulus GO:0048585 104 0.070
hepaticobiliary system development GO:0061008 98 0.069
cellular macromolecule biosynthetic process GO:0034645 224 0.069
Fly
axon ensheathment in central nervous system GO:0032291 2 0.069
positive regulation of cytokine production GO:0001819 2 0.069
cellular response to oxygen containing compound GO:1901701 20 0.068
positive regulation of cellular catabolic process GO:0031331 3 0.068
protein metabolic process GO:0019538 183 0.068
embryonic heart tube development GO:0035050 133 0.068
positive regulation of gene expression GO:0010628 71 0.067
Fly
fatty acid transport GO:0015908 1 0.067
sodium ion import GO:0097369 3 0.067
regulation of hormone levels GO:0010817 21 0.067
mesenchymal cell differentiation GO:0048762 87 0.067
muscle organ development GO:0007517 101 0.066
nerve development GO:0021675 45 0.066
positive regulation of transport GO:0051050 2 0.066
rna metabolic process GO:0016070 219 0.065
Fly
regulation of tube size GO:0035150 2 0.065
monovalent inorganic cation homeostasis GO:0055067 9 0.065
ion transport GO:0006811 114 0.065
positive regulation of epithelial cell proliferation GO:0050679 1 0.065
retina morphogenesis in camera type eye GO:0060042 79 0.065
axon guidance GO:0007411 86 0.064
Fly
negative regulation of secretion GO:0051048 2 0.064
response to vitamin GO:0033273 3 0.064
regulation of multicellular organismal process GO:0051239 277 0.064
Fly
cellular response to steroid hormone stimulus GO:0071383 31 0.063
inflammatory response GO:0006954 8 0.063
negative regulation of rna biosynthetic process GO:1902679 45 0.063
regulation of cytokine production GO:0001817 3 0.063
heart morphogenesis GO:0003007 156 0.062
regulation of signal transduction GO:0009966 225 0.062
positive regulation of canonical wnt signaling pathway GO:0090263 4 0.062
negative regulation of signaling GO:0023057 96 0.061
forebrain development GO:0030900 96 0.061
macromolecule modification GO:0043412 111 0.061
maintenance of location GO:0051235 4 0.060
blood vessel morphogenesis GO:0048514 216 0.060
muscle fiber development GO:0048747 52 0.060
developmental growth GO:0048589 166 0.059
catechol containing compound biosynthetic process GO:0009713 2 0.059
vasculature development GO:0001944 278 0.059
response to nutrient GO:0007584 3 0.059
regulation of calcium ion transport GO:0051924 2 0.059
central nervous system myelin formation GO:0032289 1 0.058
regulation of system process GO:0044057 40 0.058
small molecule metabolic process GO:0044281 77 0.058
hindbrain development GO:0030902 91 0.057
negative regulation of cell motility GO:2000146 17 0.057
skeletal system morphogenesis GO:0048705 102 0.057
angiogenesis GO:0001525 158 0.057
regulation of neurotransmitter transport GO:0051588 1 0.057
nitrogen compound transport GO:0071705 23 0.056
response to external stimulus GO:0009605 264 0.056
Fly
cellular protein catabolic process GO:0044257 4 0.056
cellular response to hormone stimulus GO:0032870 39 0.055
proteolysis GO:0006508 38 0.054
reactive oxygen species metabolic process GO:0072593 6 0.054
cellular nitrogen compound biosynthetic process GO:0044271 218 0.054
Fly
embryonic organ development GO:0048568 381 0.053
Fly
negative regulation of macromolecule metabolic process GO:0010605 76 0.053
cation transmembrane transport GO:0098655 65 0.053
regulation of programmed cell death GO:0043067 101 0.052
Mouse
regulation of circadian rhythm GO:0042752 4 0.052
blood circulation GO:0008015 87 0.052
regulation of protein catabolic process GO:0042176 1 0.052
ammonia homeostasis GO:0097272 3 0.052
organic acid metabolic process GO:0006082 31 0.052
regulation of cell differentiation GO:0045595 142 0.052
Fly
cellular amino acid metabolic process GO:0006520 7 0.051
positive regulation of apoptotic signaling pathway GO:2001235 1 0.051
catecholamine biosynthetic process GO:0042423 2 0.050
regulation of locomotion GO:0040012 55 0.050
cellular protein metabolic process GO:0044267 129 0.049
negative regulation of programmed cell death GO:0043069 58 0.049
Mouse
response to alcohol GO:0097305 14 0.048
cell fate specification GO:0001708 68 0.048
neuron neuron synaptic transmission GO:0007270 1 0.048
lateral line ganglion development GO:0048890 2 0.048
hexose transport GO:0008645 6 0.047
regulation of establishment of protein localization GO:0070201 4 0.046
response to organic cyclic compound GO:0014070 51 0.046
response to endogenous stimulus GO:0009719 83 0.046
cellular response to stress GO:0033554 62 0.045
positive regulation of cellular extravasation GO:0002693 1 0.045
chemotaxis GO:0006935 104 0.045
Fly
somite development GO:0061053 96 0.045
midbrain development GO:0030901 28 0.044
neurotransmitter transport GO:0006836 2 0.044
neuron projection morphogenesis GO:0048812 161 0.044
Fly
apoptotic process involved in development GO:1902742 2 0.044
toxin transport GO:1901998 2 0.043
oligodendrocyte differentiation GO:0048709 23 0.043
inner ear morphogenesis GO:0042472 63 0.043
regulation of cell activation GO:0050865 1 0.042
specification of symmetry GO:0009799 204 0.042
alpha amino acid metabolic process GO:1901605 3 0.042
regulation of defense response GO:0031347 14 0.042
neuron projection guidance GO:0097485 86 0.042
Fly
response to ionizing radiation GO:0010212 6 0.042
cellular response to lipopolysaccharide GO:0071222 3 0.041
cell cell signaling GO:0007267 52 0.041
regulation of cellular amine metabolic process GO:0033238 0 0.041
camera type eye morphogenesis GO:0048593 108 0.040
hematopoietic progenitor cell differentiation GO:0002244 23 0.040
negative regulation of kinase activity GO:0033673 4 0.040
modification of morphology or physiology of other organism involved in symbiotic interaction GO:0051817 4 0.040
endocrine process GO:0050886 2 0.040
heterocycle biosynthetic process GO:0018130 215 0.039
Fly
regulation of extrinsic apoptotic signaling pathway GO:2001236 3 0.039
hatching gland development GO:0048785 3 0.039
apoptotic process GO:0006915 116 0.039
Mouse
anatomical structure homeostasis GO:0060249 36 0.039
organelle localization GO:0051640 49 0.038
cell projection organization GO:0030030 284 0.038
Fly
sodium ion transport GO:0006814 24 0.037
lateral line nerve glial cell differentiation GO:0048895 6 0.037
negative regulation of map kinase activity GO:0043407 2 0.037
negative regulation of apoptotic process GO:0043066 55 0.037
Mouse
body morphogenesis GO:0010171 16 0.036
negative regulation of rna metabolic process GO:0051253 48 0.036
cellular response to molecule of bacterial origin GO:0071219 3 0.036
positive regulation of extrinsic apoptotic signaling pathway GO:2001238 1 0.036
artery morphogenesis GO:0048844 14 0.036
metal ion transport GO:0030001 58 0.036
mesenchymal cell development GO:0014031 78 0.036
response to drug GO:0042493 3 0.036
regulation of membrane potential GO:0042391 23 0.036
b cell activation GO:0042113 2 0.035
auditory receptor cell fate commitment GO:0009912 4 0.035
sodium ion transmembrane transport GO:0035725 21 0.035
hemopoiesis GO:0030097 183 0.035
Fly
regulation of macromolecule biosynthetic process GO:0010556 225 0.035
Fly
negative regulation of hormone secretion GO:0046888 2 0.035
intracellular signal transduction GO:0035556 85 0.034
anion transport GO:0006820 38 0.034
ras protein signal transduction GO:0007265 7 0.034
regulation of cellular localization GO:0060341 12 0.034
cranial ganglion development GO:0061550 3 0.034
smooth muscle contraction GO:0006939 2 0.033
nitric oxide biosynthetic process GO:0006809 2 0.033
catechol containing compound metabolic process GO:0009712 2 0.033
negative regulation of secretion by cell GO:1903531 2 0.033
wound healing GO:0042060 90 0.033
regulation of multicellular organismal development GO:2000026 223 0.033
Fly
hypotonic salinity response GO:0042539 5 0.033
sequestering of metal ion GO:0051238 3 0.033
regulation of reactive oxygen species metabolic process GO:2000377 2 0.032
negative regulation of cellular macromolecule biosynthetic process GO:2000113 48 0.032
myeloid leukocyte migration GO:0097529 12 0.032
response to estrogen GO:0043627 27 0.032
response to mechanical stimulus GO:0009612 24 0.032
detection of stimulus GO:0051606 29 0.032
cellular response to external stimulus GO:0071496 2 0.032
single organism intracellular transport GO:1902582 25 0.031
epithelial tube morphogenesis GO:0060562 148 0.031
peptide transport GO:0015833 1 0.031
establishment of localization in cell GO:0051649 77 0.031
transmembrane transport GO:0055085 120 0.031
organelle organization GO:0006996 227 0.031
dorsal ventral pattern formation GO:0009953 125 0.031
positive regulation of cell death GO:0010942 29 0.031
stem cell differentiation GO:0048863 117 0.031
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.031
cellular response to organic cyclic compound GO:0071407 38 0.031
cation transport GO:0006812 81 0.031
response to radiation GO:0009314 51 0.031
transcription from rna polymerase ii promoter GO:0006366 80 0.030
Fly
organic substance catabolic process GO:1901575 28 0.030
negative regulation of epithelial cell proliferation GO:0050680 1 0.030
synaptic growth at neuromuscular junction GO:0051124 2 0.030
response to hydrogen peroxide GO:0042542 3 0.030
modification dependent macromolecule catabolic process GO:0043632 3 0.030
positive regulation of chronic inflammatory response GO:0002678 1 0.030
cerebellum development GO:0021549 17 0.030
positive regulation of defense response GO:0031349 9 0.029
cellular response to abiotic stimulus GO:0071214 4 0.029
response to decreased oxygen levels GO:0036293 25 0.029
central nervous system neuron differentiation GO:0021953 74 0.028
water homeostasis GO:0030104 4 0.028
cellular extravasation GO:0045123 1 0.028
protein localization to plasma membrane GO:0072659 1 0.028
negative regulation of defense response GO:0031348 2 0.028
response to steroid hormone GO:0048545 35 0.028
cell proliferation GO:0008283 80 0.027
Fly
ubiquitin dependent protein catabolic process GO:0006511 3 0.027
negative regulation of cytokine production GO:0001818 1 0.027
regulation of cellular amino acid metabolic process GO:0006521 0 0.027
regulation of blood pressure GO:0008217 1 0.027
endocardial cushion formation GO:0003272 2 0.026
macromolecule catabolic process GO:0009057 15 0.026
digestive tract development GO:0048565 265 0.026
regulation of cellular response to oxidative stress GO:1900407 2 0.026
inner ear receptor cell fate commitment GO:0060120 4 0.026
melanocyte differentiation GO:0030318 26 0.026
leukocyte differentiation GO:0002521 25 0.026
extrinsic apoptotic signaling pathway in absence of ligand GO:0097192 1 0.026
negative regulation of protein phosphorylation GO:0001933 4 0.026
positive regulation of cell adhesion GO:0045785 1 0.025
apoptotic signaling pathway GO:0097190 23 0.025
organelle fusion GO:0048284 3 0.025
epithelial cell proliferation GO:0050673 17 0.025
multicellular organismal signaling GO:0035637 22 0.025
motor neuron axon guidance GO:0008045 23 0.025
somatic stem cell maintenance GO:0035019 1 0.025
negative regulation of signal transduction in absence of ligand GO:1901099 1 0.025
guanosine containing compound catabolic process GO:1901069 2 0.025
leukocyte homeostasis GO:0001776 2 0.025
regulation of sequestering of calcium ion GO:0051282 4 0.025
negative regulation of cellular metabolic process GO:0031324 77 0.025
proteasomal protein catabolic process GO:0010498 2 0.025
neuron projection development GO:0031175 180 0.025
Fly
cellular component assembly involved in morphogenesis GO:0010927 107 0.025
regulation of protein modification by small protein conjugation or removal GO:1903320 3 0.024
tube morphogenesis GO:0035239 349 0.024
nucleotide metabolic process GO:0009117 28 0.024
inorganic cation transmembrane transport GO:0098662 50 0.024
regulation of homeostatic process GO:0032844 9 0.024
connective tissue development GO:0061448 99 0.024
regulation of transcription from rna polymerase ii promoter in response to oxidative stress GO:0043619 0 0.024
symbiosis encompassing mutualism through parasitism GO:0044403 4 0.024
small molecule catabolic process GO:0044282 3 0.024
regulation of neuron apoptotic process GO:0043523 17 0.024
regulation of cellular ketone metabolic process GO:0010565 7 0.024
cellular response to extracellular stimulus GO:0031668 2 0.024
regulation of reproductive process GO:2000241 4 0.023
skeletal muscle organ development GO:0060538 78 0.023
positive regulation of neuron death GO:1901216 1 0.023
ear morphogenesis GO:0042471 64 0.023
collagen biosynthetic process GO:0032964 2 0.023
cartilage development GO:0051216 96 0.023
developmental growth involved in morphogenesis GO:0060560 86 0.023
purine nucleoside monophosphate catabolic process GO:0009128 4 0.023
positive regulation of apoptotic process GO:0043065 29 0.023
regulation of transcription from rna polymerase ii promoter in response to stress GO:0043618 0 0.023
bmp signaling pathway GO:0030509 52 0.022
response to ketone GO:1901654 1 0.022
establishment of protein localization to plasma membrane GO:0090002 1 0.022
female sex differentiation GO:0046660 4 0.022
regulation of canonical wnt signaling pathway GO:0060828 34 0.022
cellular response to estradiol stimulus GO:0071392 1 0.022
response to oxygen levels GO:0070482 25 0.022
response to glucocorticoid GO:0051384 1 0.022
ventral midline development GO:0007418 13 0.022
phenol containing compound biosynthetic process GO:0046189 4 0.022
purine containing compound metabolic process GO:0072521 29 0.022
developmental programmed cell death GO:0010623 4 0.021
tube closure GO:0060606 1 0.021
negative regulation of nucleobase containing compound metabolic process GO:0045934 59 0.021
carboxylic acid metabolic process GO:0019752 22 0.021
regulation of intracellular signal transduction GO:1902531 57 0.021
regulation of nucleotide catabolic process GO:0030811 2 0.021
atp catabolic process GO:0006200 4 0.021
regulation of leukocyte differentiation GO:1902105 5 0.021
regulation of chronic inflammatory response GO:0002676 1 0.021
skin development GO:0043588 54 0.021
regulation of cellular protein metabolic process GO:0032268 52 0.021
vasculogenesis GO:0001570 41 0.021
neuron death GO:0070997 21 0.021
regulation of dna templated transcription in response to stress GO:0043620 0 0.021

gcm2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.346
nervous system disease DOID:863 0 0.346
disease of metabolism DOID:0014667 0 0.112
sensory system disease DOID:0050155 0 0.086
eye and adnexa disease DOID:1492 0 0.086
eye disease DOID:5614 0 0.086
inherited metabolic disorder DOID:655 0 0.052
central nervous system disease DOID:331 0 0.032
brain disease DOID:936 0 0.032