Danio rerio

12 known processes

gdnf

glial cell derived neurotrophic factor

(Aliases: gdnfa)

gdnf biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
central nervous system development GO:0007417 387 0.956
Rat
eye development GO:0001654 277 0.933
Rat
nucleobase containing compound biosynthetic process GO:0034654 205 0.888
Human
sensory organ development GO:0007423 393 0.818
Rat
immune system process GO:0002376 241 0.788
negative regulation of biological process GO:0048519 304 0.713
Human Mouse
kidney development GO:0001822 92 0.710
Human Mouse Rat
renal system development GO:0072001 94 0.696
Human Mouse Rat
negative regulation of cellular process GO:0048523 283 0.684
Human Mouse
locomotion GO:0040011 313 0.667
Human
regulation of multicellular organismal process GO:0051239 277 0.615
Human Mouse Rat
regulation of cell differentiation GO:0045595 142 0.611
Mouse
regulation of cellular metabolic process GO:0031323 320 0.609
Human
anterior posterior pattern specification GO:0009952 152 0.589
camera type eye development GO:0043010 222 0.585
Rat
hematopoietic or lymphoid organ development GO:0048534 191 0.571
mechanosensory lateral line system development GO:0048881 49 0.571
positive regulation of transcription dna templated GO:0045893 57 0.562
Human
positive regulation of rna metabolic process GO:0051254 59 0.562
Human
nitrogen compound metabolic process GO:0006807 319 0.558
Human
localization of cell GO:0051674 244 0.550
Human
regulation of mechanoreceptor differentiation GO:0045631 1 0.546
regionalization GO:0003002 274 0.504
Mouse
eye morphogenesis GO:0048592 144 0.498
forebrain development GO:0030900 96 0.491
renal tubule morphogenesis GO:0061333 1 0.486
Human Mouse Rat
positive regulation of cellular biosynthetic process GO:0031328 68 0.480
Human
cellular macromolecule metabolic process GO:0044260 391 0.458
Human
regulation of primary metabolic process GO:0080090 311 0.451
Human
cellular component movement GO:0006928 335 0.431
Human
sensory organ morphogenesis GO:0090596 200 0.423
nephron development GO:0072006 31 0.403
Human Mouse Rat
hindbrain development GO:0030902 91 0.401
olfactory lobe development GO:0021988 4 0.400
somitogenesis GO:0001756 87 0.396
biosynthetic process GO:0009058 294 0.395
Human
embryo development ending in birth or egg hatching GO:0009792 271 0.391
embryonic organ development GO:0048568 381 0.390
somite development GO:0061053 96 0.380
regulation of organ growth GO:0046620 3 0.368
nephron tubule morphogenesis GO:0072078 1 0.363
Human Mouse Rat
heart development GO:0007507 313 0.358
nephron epithelium development GO:0072009 16 0.350
Human Mouse Rat
regulation of transport GO:0051049 45 0.347
Human
skeletal system development GO:0001501 181 0.345
cellular biosynthetic process GO:0044249 286 0.339
Human
regulation of hormone secretion GO:0046883 2 0.339
female sex differentiation GO:0046660 4 0.337
macromolecule biosynthetic process GO:0009059 227 0.337
Human
hindbrain morphogenesis GO:0021575 22 0.333
regulation of inner ear receptor cell differentiation GO:2000980 1 0.322
inner ear development GO:0048839 126 0.322
renal tubule development GO:0061326 5 0.314
Human Mouse Rat
olfactory bulb development GO:0021772 4 0.310
rna biosynthetic process GO:0032774 181 0.310
Human
appendage development GO:0048736 80 0.307
regulation of cell development GO:0060284 100 0.302
Mouse
aorta morphogenesis GO:0035909 3 0.297
regulation of cellular component organization GO:0051128 86 0.296
Mouse
positive regulation of nucleobase containing compound metabolic process GO:0045935 69 0.293
Human
posterior lateral line development GO:0048916 38 0.292
death GO:0016265 121 0.290
Human Mouse
sensory system development GO:0048880 76 0.289
organic cyclic compound biosynthetic process GO:1901362 223 0.288
Human
regulation of neuron differentiation GO:0045664 56 0.284
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.280
Human
response to external stimulus GO:0009605 264 0.278
regulation of nitrogen compound metabolic process GO:0051171 251 0.273
Human
appendage morphogenesis GO:0035107 56 0.273
circadian sleep wake cycle sleep GO:0050802 1 0.261
regulation of cell migration GO:0030334 40 0.250
regulation of developmental process GO:0050793 247 0.248
Human Mouse Rat
specification of organ identity GO:0010092 2 0.248
Mouse
posterior lateral line system development GO:0048915 46 0.240
negative regulation of metabolic process GO:0009892 86 0.239
organic substance biosynthetic process GO:1901576 289 0.239
Human
aging GO:0007568 2 0.238
lateral line system development GO:0048925 76 0.229
regulation of transcription from rna polymerase ii promoter GO:0006357 114 0.220
Human
response to glucose GO:0009749 3 0.220
retina development in camera type eye GO:0060041 146 0.220
Rat
positive regulation of macromolecule biosynthetic process GO:0010557 59 0.215
Human
positive regulation of biological process GO:0048518 253 0.215
Human Mouse Rat
retina layer formation GO:0010842 24 0.213
nephron epithelium morphogenesis GO:0072088 1 0.212
Human Mouse Rat
positive regulation of biosynthetic process GO:0009891 68 0.212
Human
camera type eye morphogenesis GO:0048593 108 0.210
lateral line development GO:0048882 66 0.208
regulation of apoptotic process GO:0042981 98 0.207
Human Mouse
response to organic substance GO:0010033 153 0.201
Rat
response to chemical GO:0042221 320 0.197
Rat
heart morphogenesis GO:0003007 156 0.191
epithelial cell differentiation GO:0030855 116 0.189
Mouse Rat
regulation of anatomical structure morphogenesis GO:0022603 130 0.188
Human Mouse Rat
stem cell proliferation GO:0072089 4 0.188
kidney epithelium development GO:0072073 23 0.187
Human Mouse Rat
regulation of organ morphogenesis GO:2000027 35 0.186
Human Mouse Rat
retina morphogenesis in camera type eye GO:0060042 79 0.186
heterocycle biosynthetic process GO:0018130 215 0.182
Human
regulation of cell death GO:0010941 103 0.181
Human Mouse
head development GO:0060322 303 0.181
Rat
regulation of nucleic acid templated transcription GO:1903506 213 0.181
Human
regulation of nervous system development GO:0051960 90 0.181
enzyme linked receptor protein signaling pathway GO:0007167 106 0.179
nucleic acid templated transcription GO:0097659 181 0.178
Human
response to hormone GO:0009725 48 0.178
Rat
female gonad development GO:0008585 4 0.177
response to wounding GO:0009611 116 0.177
Rat
nephron morphogenesis GO:0072028 2 0.175
Human Mouse Rat
regulation of gene expression GO:0010468 265 0.173
Human
cellular response to organic substance GO:0071310 105 0.170
Rat
pancreas development GO:0031016 84 0.169
positive regulation of nucleic acid templated transcription GO:1903508 57 0.168
Human
aromatic compound biosynthetic process GO:0019438 217 0.167
Human
embryonic skeletal system morphogenesis GO:0048704 93 0.167
regulation of multicellular organismal development GO:2000026 223 0.165
Human Mouse Rat
cell migration GO:0016477 237 0.164
Human
muscle structure development GO:0061061 196 0.164
cardiocyte differentiation GO:0035051 44 0.163
brain development GO:0007420 293 0.162
Rat
chordate embryonic development GO:0043009 271 0.158
signal transduction GO:0007165 455 0.156
Human
morphogenesis of embryonic epithelium GO:0016331 30 0.150
Human Mouse Rat
positive regulation of developmental process GO:0051094 50 0.146
Human Mouse Rat
cellular response to external stimulus GO:0071496 2 0.145
forebrain regionalization GO:0021871 4 0.143
regulation of fatty acid metabolic process GO:0019217 1 0.143
single organism transport GO:0044765 206 0.143
Human
positive regulation of cellular metabolic process GO:0031325 94 0.142
Human
regulation of metabolic process GO:0019222 359 0.141
Human
negative regulation of cell death GO:0060548 60 0.141
Human Mouse
regulation of neurogenesis GO:0050767 87 0.139
neuromast development GO:0048884 46 0.138
response to nicotine GO:0035094 2 0.138
segmentation GO:0035282 97 0.137
cell death GO:0008219 121 0.137
Human Mouse
skeletal system morphogenesis GO:0048705 102 0.135
lipid oxidation GO:0034440 1 0.134
establishment of localization GO:0051234 244 0.132
Human
regulation of rna biosynthetic process GO:2001141 213 0.132
Human
circadian sleep wake cycle process GO:0022410 2 0.128
photoreceptor cell outer segment organization GO:0035845 9 0.128
endocrine pancreas development GO:0031018 27 0.127
glucose homeostasis GO:0042593 1 0.126
regulation of macromolecule metabolic process GO:0060255 317 0.126
Human
hormone secretion GO:0046879 2 0.122
cell motility GO:0048870 244 0.121
Human
response to monosaccharide GO:0034284 3 0.121
chemotaxis GO:0006935 104 0.121
embryonic organ morphogenesis GO:0048562 274 0.120
regulation of immune system process GO:0002682 34 0.120
negative regulation of cell differentiation GO:0045596 46 0.119
negative regulation of stem cell differentiation GO:2000737 2 0.117
nucleic acid metabolic process GO:0090304 244 0.116
Human
regulation of cell projection organization GO:0031344 44 0.115
regulation of heart growth GO:0060420 2 0.114
gastrulation GO:0007369 208 0.114
generation of neurons GO:0048699 385 0.113
Human Rat
response to drug GO:0042493 3 0.111
urogenital system development GO:0001655 97 0.111
Human Mouse Rat
response to alkaloid GO:0043279 2 0.109
fin morphogenesis GO:0033334 53 0.109
cellular nitrogen compound biosynthetic process GO:0044271 218 0.107
Human
cognition GO:0050890 1 0.106
rostrocaudal neural tube patterning GO:0021903 29 0.105
mechanosensory behavior GO:0007638 2 0.105
cell surface receptor signaling pathway GO:0007166 325 0.104
Human
regulation of programmed cell death GO:0043067 101 0.104
Human Mouse
single organism localization GO:1902578 225 0.103
Human
hormone transport GO:0009914 2 0.103
cellular response to stress GO:0033554 62 0.102
compound eye development GO:0048749 2 0.099
cell morphogenesis involved in differentiation GO:0000904 195 0.099
Mouse Rat
negative regulation of epithelial cell migration GO:0010633 1 0.097
cell fate commitment GO:0045165 99 0.097
Mouse
inner ear receptor cell fate commitment GO:0060120 4 0.097
auditory receptor cell fate commitment GO:0009912 4 0.097
pectoral fin development GO:0033339 50 0.095
positive regulation of cellular component biogenesis GO:0044089 3 0.094
response to hexose GO:0009746 3 0.092
positive regulation of rna biosynthetic process GO:1902680 57 0.091
Human
heterocycle metabolic process GO:0046483 290 0.090
Human
positive regulation of stem cell proliferation GO:2000648 1 0.090
response to light stimulus GO:0009416 46 0.090
glucocorticoid metabolic process GO:0008211 2 0.089
nucleobase containing compound metabolic process GO:0006139 274 0.089
Human
apoptotic process GO:0006915 116 0.089
Human Mouse
neural retina development GO:0003407 49 0.089
opioid receptor signaling pathway GO:0038003 3 0.088
single organism metabolic process GO:0044710 217 0.088
Human
pharyngeal muscle development GO:0043282 4 0.087
embryonic cranial skeleton morphogenesis GO:0048701 90 0.087
phagocytosis GO:0006909 3 0.087
cellular nitrogen compound metabolic process GO:0034641 290 0.086
Human
development of primary female sexual characteristics GO:0046545 4 0.085
exocrine pancreas development GO:0031017 28 0.084
positive regulation of neurogenesis GO:0050769 24 0.083
ribonucleotide biosynthetic process GO:0009260 20 0.083
monoamine transport GO:0015844 1 0.082
Human
cellular response to hormone stimulus GO:0032870 39 0.082
Rat
organic acid metabolic process GO:0006082 31 0.082
developmental growth GO:0048589 166 0.082
regulation of cellular ketone metabolic process GO:0010565 7 0.081
response to ketone GO:1901654 1 0.081
Rat
neuron projection morphogenesis GO:0048812 161 0.081
midbrain hindbrain boundary development GO:0030917 23 0.081
regulation of locomotion GO:0040012 55 0.080
cellular ketone metabolic process GO:0042180 11 0.080
regulation of circadian rhythm GO:0042752 4 0.079
positive regulation of epithelial cell proliferation GO:0050679 1 0.078
regulation of hormone levels GO:0010817 21 0.077
response to oxygen containing compound GO:1901700 55 0.077
Rat
morphogenesis of an epithelium GO:0002009 333 0.077
Human Mouse Rat
regulation of cellular carbohydrate metabolic process GO:0010675 4 0.077
negative regulation of apoptotic process GO:0043066 55 0.077
Human Mouse
hemopoiesis GO:0030097 183 0.076
metencephalon development GO:0022037 27 0.076
nitrogen compound transport GO:0071705 23 0.074
Human
positive regulation of cell proliferation GO:0008284 15 0.072
fatty acid catabolic process GO:0009062 1 0.072
positive regulation of multicellular organismal process GO:0051240 52 0.072
Human Mouse Rat
regulation of response to stress GO:0080134 36 0.072
negative regulation of signaling GO:0023057 96 0.072
Human
endocardium formation GO:0060214 1 0.071
regulation of behavior GO:0050795 24 0.070
cellular amine metabolic process GO:0044106 2 0.070
larval development GO:0002164 2 0.070
embryonic skeletal system development GO:0048706 97 0.070
positive regulation of striated muscle tissue development GO:0045844 1 0.069
nucleoside phosphate biosynthetic process GO:1901293 21 0.069
response to endogenous stimulus GO:0009719 83 0.069
Rat
epithelial cell fate commitment GO:0072148 11 0.068
positive regulation of embryonic development GO:0040019 3 0.067
Human
embryonic eye morphogenesis GO:0048048 30 0.067
odontogenesis of dentin containing tooth GO:0042475 1 0.067
nephron tubule development GO:0072080 4 0.067
Human Mouse Rat
regulation of catalytic activity GO:0050790 55 0.067
Human
developmental programmed cell death GO:0010623 4 0.067
cyclic nucleotide metabolic process GO:0009187 18 0.067
g protein coupled receptor signaling pathway GO:0007186 74 0.066
ear morphogenesis GO:0042471 64 0.066
negative regulation of nucleobase containing compound metabolic process GO:0045934 59 0.065
regulation of signaling GO:0023051 235 0.065
Human
regulation of circadian sleep wake cycle GO:0042749 1 0.065
organic substance transport GO:0071702 58 0.065
Human
organophosphate biosynthetic process GO:0090407 23 0.064
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.064
Human
response to steroid hormone GO:0048545 35 0.064
Rat
positive regulation of transport GO:0051050 2 0.064
angiogenesis GO:0001525 158 0.064
hematopoietic progenitor cell differentiation GO:0002244 23 0.064
transcription from rna polymerase ii promoter GO:0006366 80 0.063
Human
regulation of transcription dna templated GO:0006355 213 0.062
Human
somatic stem cell maintenance GO:0035019 1 0.062
organonitrogen compound metabolic process GO:1901564 74 0.062
organic cyclic compound metabolic process GO:1901360 301 0.062
Human
response to stress GO:0006950 263 0.061
Rat
positive regulation of cellular process GO:0048522 201 0.061
Human Mouse
forebrain neuron development GO:0021884 7 0.061
sensory perception GO:0007600 39 0.061
photoreceptor cell differentiation GO:0046530 55 0.061
cyclic purine nucleotide metabolic process GO:0052652 18 0.060
negative regulation of signal transduction GO:0009968 94 0.060
Human
entrainment of circadian clock GO:0009649 2 0.060
regulation of guanylate cyclase activity GO:0031282 6 0.059
regulation of localization GO:0032879 104 0.059
Human
embryonic camera type eye development GO:0031076 29 0.059
response to lipid GO:0033993 60 0.059
Rat
epithelial tube formation GO:0072175 19 0.058
Human Mouse Rat
stem cell maintenance GO:0019827 4 0.058
auditory receptor cell fate determination GO:0042668 2 0.058
response to carbohydrate GO:0009743 3 0.058
embryonic heart tube morphogenesis GO:0003143 108 0.058
system process GO:0003008 185 0.057
Mouse
central nervous system neuron differentiation GO:0021953 74 0.057
cellular component assembly GO:0022607 170 0.057
glomerulus vasculature development GO:0072012 2 0.057
circadian sleep wake cycle GO:0042745 2 0.056
cell projection organization GO:0030030 284 0.056
Human
fatty acid oxidation GO:0019395 1 0.056
positive regulation of mesenchymal cell proliferation GO:0002053 1 0.056
ear development GO:0043583 127 0.055
regulation of stem cell proliferation GO:0072091 2 0.055
embryonic digestive tract morphogenesis GO:0048557 3 0.055
pronephric nephron development GO:0039019 14 0.054
pronephric nephron tubule development GO:0039020 2 0.054
regulation of cellular component movement GO:0051270 55 0.054
neuron differentiation GO:0030182 353 0.053
Human Rat
negative regulation of cellular biosynthetic process GO:0031327 55 0.053
regulation of phosphate metabolic process GO:0019220 43 0.052
endocrine system development GO:0035270 65 0.052
endocardial cushion formation GO:0003272 2 0.051
thalamus development GO:0021794 6 0.051
blood circulation GO:0008015 87 0.050
neuron projection development GO:0031175 180 0.050
Human
regulation of inflammatory response GO:0050727 2 0.050
negative regulation of programmed cell death GO:0043069 58 0.050
Human Mouse
posterior lateral line neuromast primordium migration GO:0048920 12 0.049
regulation of developmental growth GO:0048638 38 0.049
digestive system development GO:0055123 289 0.049
neurological system process GO:0050877 62 0.049
dorsal ventral pattern formation GO:0009953 125 0.049
response to organic cyclic compound GO:0014070 51 0.049
Rat
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.049
negative regulation of cellular macromolecule biosynthetic process GO:2000113 48 0.048
positive regulation of muscle organ development GO:0048636 1 0.048
regulation of fatty acid beta oxidation GO:0031998 1 0.048
response to glucocorticoid GO:0051384 1 0.048
Rat
transcription dna templated GO:0006351 181 0.048
Human
cellular response to endogenous stimulus GO:0071495 68 0.048
Rat
actin filament based process GO:0030029 64 0.047
fin development GO:0033333 77 0.047
regulation of epithelial cell proliferation GO:0050678 3 0.047
positive regulation of macromolecule metabolic process GO:0010604 93 0.047
Human
regulation of cellular biosynthetic process GO:0031326 245 0.046
Human
embryonic epithelial tube formation GO:0001838 17 0.046
Human Mouse Rat
blood vessel development GO:0001568 246 0.045
negative regulation of macromolecule metabolic process GO:0010605 76 0.045
small molecule metabolic process GO:0044281 77 0.045
regulation of cardiac muscle tissue development GO:0055024 1 0.044
cellular response to hypoxia GO:0071456 1 0.044
heart looping GO:0001947 94 0.044
spinal cord development GO:0021510 46 0.044
neuromast primordium migration GO:0048883 12 0.044
carboxylic acid metabolic process GO:0019752 22 0.043
aorta development GO:0035904 4 0.043
hypothalamus cell differentiation GO:0021979 4 0.043
purine nucleotide biosynthetic process GO:0006164 20 0.043
negative regulation of gene expression GO:0010629 65 0.043
inner ear morphogenesis GO:0042472 63 0.043
negative regulation of macromolecule biosynthetic process GO:0010558 48 0.043
skin development GO:0043588 54 0.043
cellular response to organic cyclic compound GO:0071407 38 0.043
Rat
negative regulation of striated muscle tissue development GO:0045843 2 0.042
negative regulation of cell fate commitment GO:0010454 13 0.042
response to radiation GO:0009314 51 0.042
regulation of cell proliferation involved in heart morphogenesis GO:2000136 2 0.042
negative regulation of developmental process GO:0051093 65 0.042
multicellular organism growth GO:0035264 4 0.042
gabaergic neuron differentiation GO:0097154 2 0.041
retinal cone cell differentiation GO:0042670 12 0.041
rhombomere development GO:0021546 19 0.041
negative regulation of rna metabolic process GO:0051253 48 0.041
peripheral nervous system neuron development GO:0048935 22 0.041
homeostatic process GO:0042592 142 0.040
fatty acid beta oxidation GO:0006635 1 0.040
single organism organelle organization GO:1902589 199 0.040
regulation of neuron migration GO:2001222 2 0.040
mesenchymal cell proliferation GO:0010463 1 0.040
positive regulation of cytoskeleton organization GO:0051495 3 0.040
embryonic pectoral fin morphogenesis GO:0035118 24 0.039
peripheral nervous system neuron differentiation GO:0048934 28 0.039
specification of symmetry GO:0009799 204 0.039
embryonic skeletal joint development GO:0072498 3 0.039
negative regulation of secretion GO:0051048 2 0.039
epithelial tube morphogenesis GO:0060562 148 0.039
Human Mouse Rat
apoptotic process involved in development GO:1902742 2 0.039
neuron development GO:0048666 262 0.039
Human
epidermis development GO:0008544 48 0.038
type b pancreatic cell development GO:0003323 4 0.038
response to corticosteroid GO:0031960 1 0.038
Rat
response to growth factor GO:0070848 39 0.038
pectoral fin morphogenesis GO:0035138 29 0.038
positive regulation of cell differentiation GO:0045597 30 0.038
Mouse
organelle localization GO:0051640 49 0.038
negative regulation of cell communication GO:0010648 96 0.037
Human
camera type eye photoreceptor cell differentiation GO:0060219 19 0.037
regulation of vesicle mediated transport GO:0060627 9 0.037
glial cell migration GO:0008347 3 0.037
rhythmic process GO:0048511 21 0.037
kupffer s vesicle development GO:0070121 50 0.037
negative regulation of protein phosphorylation GO:0001933 4 0.037
diencephalon development GO:0021536 58 0.036
embryonic viscerocranium morphogenesis GO:0048703 52 0.036
digestive system process GO:0022600 9 0.036
renal system vasculature development GO:0061437 2 0.036
regulation of neurotransmitter secretion GO:0046928 1 0.036
regulation of blood pressure GO:0008217 1 0.036
hepatocyte proliferation GO:0072574 2 0.036
kidney morphogenesis GO:0060993 15 0.035
Human Mouse Rat
glomerulus development GO:0032835 27 0.035
cellular response to extracellular stimulus GO:0031668 2 0.035
forebrain generation of neurons GO:0021872 14 0.035
negative regulation of gliogenesis GO:0014014 1 0.035
embryonic heart tube development GO:0035050 133 0.034
regulation of circadian sleep wake cycle sleep GO:0045187 1 0.034
adenohypophysis development GO:0021984 15 0.034
multicellular organismal response to stress GO:0033555 2 0.034
developmental induction GO:0031128 10 0.033
Mouse
neuron fate specification GO:0048665 20 0.032
regulation of stem cell differentiation GO:2000736 4 0.032
cardiogenic plate morphogenesis GO:0003142 1 0.032
peptide transport GO:0015833 1 0.032
purine ribonucleotide biosynthetic process GO:0009152 20 0.032
outflow tract morphogenesis GO:0003151 1 0.031
cell proliferation GO:0008283 80 0.031
Rat
kidney vasculature development GO:0061440 2 0.031
defense response GO:0006952 47 0.031
organ formation GO:0048645 17 0.031
Mouse
cerebellum development GO:0021549 17 0.031
transport GO:0006810 220 0.031
Human
regulation of growth GO:0040008 42 0.031
regulation of axonogenesis GO:0050770 32 0.031
regulation of rna metabolic process GO:0051252 224 0.031
Human
regulation of response to stimulus GO:0048583 269 0.031
Human
axon development GO:0061564 166 0.030
cellular aromatic compound metabolic process GO:0006725 295 0.030
Human
telencephalon development GO:0021537 14 0.030
rna metabolic process GO:0016070 219 0.030
Human
response to estrogen GO:0043627 27 0.030
immune system development GO:0002520 191 0.030
positive regulation of cell communication GO:0010647 56 0.029
positive regulation of metabolic process GO:0009893 108 0.029
Human
digestive tract development GO:0048565 265 0.029
neuron fate determination GO:0048664 2 0.029
regulation of protein complex assembly GO:0043254 3 0.029
negative regulation of secretion by cell GO:1903531 2 0.029
cgmp metabolic process GO:0046068 7 0.029
organelle organization GO:0006996 227 0.029
cellular macromolecule biosynthetic process GO:0034645 224 0.028
Human
regulation of receptor mediated endocytosis GO:0048259 4 0.028
septum transversum development GO:0003343 4 0.028
liver development GO:0001889 96 0.028
taxis GO:0042330 109 0.028
regulation of phosphorus metabolic process GO:0051174 43 0.028
cellular response to starvation GO:0009267 1 0.027
negative regulation of protein kinase b signaling GO:0051898 2 0.027
growth GO:0040007 174 0.027
cellular localization GO:0051641 97 0.027
positive regulation of endothelial cell differentiation GO:0045603 2 0.027
negative regulation of cell migration GO:0030336 17 0.027
regulation of mesenchymal cell proliferation GO:0010464 1 0.026
oxoacid metabolic process GO:0043436 31 0.026
embryonic heart tube formation GO:0003144 1 0.026
epidermal cell differentiation GO:0009913 36 0.026
negative regulation of nitrogen compound metabolic process GO:0051172 59 0.026
sensory perception of pain GO:0019233 1 0.026
positive regulation of gene expression GO:0010628 71 0.026
Human
regulation of lipid catabolic process GO:0050994 2 0.026
neural tube patterning GO:0021532 33 0.026
regulation of neuron projection development GO:0010975 40 0.025
macromolecular complex assembly GO:0065003 35 0.025
foregut morphogenesis GO:0007440 4 0.025
regulation of synapse organization GO:0050807 3 0.025
cellular component biogenesis GO:0044085 178 0.025
hepaticobiliary system development GO:0061008 98 0.025
glandular epithelial cell differentiation GO:0002067 9 0.025
endocardial cushion morphogenesis GO:0003203 3 0.025
smooth muscle tissue development GO:0048745 1 0.025
muscle tissue development GO:0060537 110 0.025
neural tube development GO:0021915 62 0.025
cell proliferation involved in heart morphogenesis GO:0061323 2 0.025
purine containing compound biosynthetic process GO:0072522 20 0.024
neuron death GO:0070997 21 0.024
Human Mouse
carbohydrate homeostasis GO:0033500 1 0.024
pronephros development GO:0048793 69 0.024
regulation of reproductive process GO:2000241 4 0.024
tube formation GO:0035148 25 0.024
Human Mouse Rat
distal tubule development GO:0072017 1 0.024
cellular response to steroid hormone stimulus GO:0071383 31 0.024
Rat
negative regulation of kinase activity GO:0033673 4 0.024
otic vesicle development GO:0071599 42 0.024
amine metabolic process GO:0009308 2 0.024
regulation of membrane potential GO:0042391 23 0.024
establishment of localization in cell GO:0051649 77 0.023
positive regulation of transcription from rna polymerase ii promoter GO:0045944 22 0.023
Human
negative regulation of cell fate specification GO:0009996 11 0.023
vestibular receptor cell development GO:0060118 3 0.023
positive regulation of signaling GO:0023056 56 0.023
regulation of axon extension GO:0030516 24 0.023
regulation of cytokine production GO:0001817 3 0.023
morphogenesis of a branching structure GO:0001763 21 0.023
Human Mouse Rat
heart growth GO:0060419 7 0.023
negative regulation of biosynthetic process GO:0009890 55 0.023
epithelial cell development GO:0002064 42 0.023
Mouse Rat
positive regulation of gastrulation GO:2000543 2 0.023
ectodermal placode morphogenesis GO:0071697 32 0.023
branching morphogenesis of an epithelial tube GO:0048754 15 0.023
Human Mouse Rat
phosphate containing compound metabolic process GO:0006796 108 0.022
embryonic hemopoiesis GO:0035162 53 0.022
cell cycle GO:0007049 93 0.022
tube closure GO:0060606 1 0.022
heterophilic cell cell adhesion via plasma membrane cell adhesion molecules GO:0007157 2 0.022
gland development GO:0048732 143 0.022
intracellular estrogen receptor signaling pathway GO:0030520 3 0.022
muscle cell migration GO:0014812 4 0.022
visual perception GO:0007601 17 0.022
lateral inhibition GO:0046331 1 0.022
gene expression GO:0010467 252 0.022
Human
regulation of cellular amine metabolic process GO:0033238 0 0.022
positive regulation of cell development GO:0010720 25 0.021
Mouse
regulation of mesodermal cell fate specification GO:0042661 9 0.021
steroid hormone mediated signaling pathway GO:0043401 9 0.021
inner ear receptor cell differentiation GO:0060113 29 0.021
otolith morphogenesis GO:0032474 8 0.021

gdnf disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.027
Human
reproductive system disease DOID:15 0 0.027
disease of metabolism DOID:0014667 0 0.026
urinary system disease DOID:18 0 0.024