Danio rerio

34 known processes

gh1

growth hormone 1

(Aliases: ghl)

gh1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
immune system process GO:0002376 241 0.595
pigmentation GO:0043473 85 0.570
Zebrafish
cell surface receptor signaling pathway GO:0007166 325 0.428
positive regulation of biological process GO:0048518 253 0.424
sensory organ development GO:0007423 393 0.394
regulation of metabolic process GO:0019222 359 0.382
regulation of multicellular organismal development GO:2000026 223 0.327
Rat
hematopoietic or lymphoid organ development GO:0048534 191 0.316
regulation of nitrogen compound metabolic process GO:0051171 251 0.284
multicellular organism growth GO:0035264 4 0.271
Mouse
regulation of primary metabolic process GO:0080090 311 0.269
regulation of type b pancreatic cell development GO:2000074 1 0.240
circadian sleep wake cycle process GO:0022410 2 0.231
hemopoiesis GO:0030097 183 0.224
positive regulation of macromolecule biosynthetic process GO:0010557 59 0.186
extrinsic apoptotic signaling pathway GO:0097191 3 0.171
localization of cell GO:0051674 244 0.168
regulation of multicellular organism growth GO:0040014 4 0.166
Mouse
negative regulation of cellular process GO:0048523 283 0.165
Zebrafish Rat
hormone transport GO:0009914 2 0.162
response to endogenous stimulus GO:0009719 83 0.158
Zebrafish Mouse Rat
response to light stimulus GO:0009416 46 0.158
Rat
stem cell proliferation GO:0072089 4 0.157
Rat
regulation of cellular carbohydrate metabolic process GO:0010675 4 0.155
regulation of stem cell proliferation GO:0072091 2 0.148
signal transduction GO:0007165 455 0.143
Rat
organic cyclic compound metabolic process GO:1901360 301 0.137
Rat
regulation of circadian sleep wake cycle GO:0042749 1 0.136
cellular macromolecule metabolic process GO:0044260 391 0.133
nucleic acid metabolic process GO:0090304 244 0.132
system process GO:0003008 185 0.132
response to abiotic stimulus GO:0009628 122 0.130
Rat
lipid catabolic process GO:0016042 4 0.128
carboxylic acid metabolic process GO:0019752 22 0.113
regulation of biological quality GO:0065008 263 0.112
Rat
cellular ketone metabolic process GO:0042180 11 0.110
endocrine process GO:0050886 2 0.103
regulation of developmental process GO:0050793 247 0.100
Mouse Rat
positive regulation of stem cell proliferation GO:2000648 1 0.099
regulation of signaling GO:0023051 235 0.099
endocrine hormone secretion GO:0060986 2 0.098
energy reserve metabolic process GO:0006112 2 0.097
response to external stimulus GO:0009605 264 0.093
Mouse
embryonic skeletal joint development GO:0072498 3 0.092
positive regulation of cellular metabolic process GO:0031325 94 0.091
Rat
response to nicotine GO:0035094 2 0.088
response to peptide hormone GO:0043434 6 0.086
Zebrafish Mouse Rat
post embryonic organ morphogenesis GO:0048563 1 0.084
circulatory system process GO:0003013 87 0.083
cellular carbohydrate metabolic process GO:0044262 4 0.082
positive regulation of catabolic process GO:0009896 4 0.078
ph reduction GO:0045851 1 0.077
regulation of gene expression GO:0010468 265 0.074
positive regulation of jak stat cascade GO:0046427 2 0.073
small molecule metabolic process GO:0044281 77 0.071
response to radiation GO:0009314 51 0.071
Rat
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.070
myeloid cell differentiation GO:0030099 86 0.070
regulation of hormone secretion GO:0046883 2 0.070
response to stress GO:0006950 263 0.069
defense response GO:0006952 47 0.068
sensory perception of smell GO:0007608 2 0.067
amine metabolic process GO:0009308 2 0.064
programmed cell death GO:0012501 119 0.064
Zebrafish
regulation of response to stimulus GO:0048583 269 0.064
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.064
tissue regeneration GO:0042246 74 0.063
positive regulation of cellular amine metabolic process GO:0033240 0 0.063
gene expression GO:0010467 252 0.063
embryonic organ development GO:0048568 381 0.062
g protein coupled receptor signaling pathway GO:0007186 74 0.062
cellular aromatic compound metabolic process GO:0006725 295 0.062
response to peptide GO:1901652 6 0.062
Zebrafish Mouse Rat
aging GO:0007568 2 0.060
regulation of cellular ph GO:0030641 1 0.057
establishment of localization GO:0051234 244 0.056
Zebrafish
positive regulation of gastrulation GO:2000543 2 0.054
regulation of cellular ketone metabolic process GO:0010565 7 0.054
nuclear transport GO:0051169 4 0.054
positive regulation of apoptotic signaling pathway GO:2001235 1 0.053
negative regulation of biological process GO:0048519 304 0.053
Zebrafish Rat
regulation of cellular biosynthetic process GO:0031326 245 0.052
Rat
enzyme linked receptor protein signaling pathway GO:0007167 106 0.052
embryonic organ morphogenesis GO:0048562 274 0.052
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.051
regulation of blood pressure GO:0008217 1 0.049
heterocycle metabolic process GO:0046483 290 0.049
circadian sleep wake cycle GO:0042745 2 0.049
response to chemical GO:0042221 320 0.047
Zebrafish Mouse Rat
response to nitrogen compound GO:1901698 19 0.047
Zebrafish Mouse Rat
digestive system development GO:0055123 289 0.044
blood circulation GO:0008015 87 0.044
signal transduction in absence of ligand GO:0038034 1 0.044
camera type eye development GO:0043010 222 0.043
photoperiodism GO:0009648 11 0.043
nucleobase containing compound biosynthetic process GO:0034654 205 0.042
cell death GO:0008219 121 0.042
Zebrafish Rat
immune system development GO:0002520 191 0.042
wound healing GO:0042060 90 0.041
cellular nitrogen compound metabolic process GO:0034641 290 0.040
regulation of circadian sleep wake cycle sleep GO:0045187 1 0.040
regulation of cellular metabolic process GO:0031323 320 0.040
Rat
nitrogen compound metabolic process GO:0006807 319 0.040
extraocular skeletal muscle development GO:0002074 3 0.040
generation of neurons GO:0048699 385 0.039
Rat
regulation of extrinsic apoptotic signaling pathway GO:2001236 3 0.039
glucose homeostasis GO:0042593 1 0.039
regulation of catalytic activity GO:0050790 55 0.039
cellular protein catabolic process GO:0044257 4 0.039
regulation of cell migration GO:0030334 40 0.039
macromolecule modification GO:0043412 111 0.039
cellular amine metabolic process GO:0044106 2 0.038
sequestering of metal ion GO:0051238 3 0.038
endocardium morphogenesis GO:0003160 4 0.037
caudal fin development GO:0033336 9 0.036
positive regulation of cellular carbohydrate metabolic process GO:0010676 1 0.036
regulation of growth GO:0040008 42 0.036
Mouse Rat
regulation of apoptotic process GO:0042981 98 0.035
Zebrafish
pigment granule aggregation in cell center GO:0051877 8 0.035
Zebrafish
er nucleus signaling pathway GO:0006984 2 0.035
regulation of protein ubiquitination GO:0031396 3 0.035
response to hydrogen peroxide GO:0042542 3 0.035
regulation of hormone levels GO:0010817 21 0.035
Rat
growth GO:0040007 174 0.035
Mouse Rat
intracellular signal transduction GO:0035556 85 0.035
sequestering of calcium ion GO:0051208 3 0.035
polyol metabolic process GO:0019751 1 0.034
fin regeneration GO:0031101 51 0.034
calcium ion dependent exocytosis GO:0017156 1 0.034
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 42 0.034
cell morphogenesis GO:0000902 289 0.034
skeletal system development GO:0001501 181 0.034
proteasomal protein catabolic process GO:0010498 2 0.033
response to topologically incorrect protein GO:0035966 2 0.033
inner ear development GO:0048839 126 0.032
inositol lipid mediated signaling GO:0048017 2 0.032
neuron development GO:0048666 262 0.032
epithelial cell development GO:0002064 42 0.032
organic acid metabolic process GO:0006082 31 0.031
cytokinesis GO:0000910 3 0.031
regulation of intracellular ph GO:0051453 1 0.031
cell substrate adhesion GO:0031589 4 0.031
entrainment of circadian clock GO:0009649 2 0.031
regulation of localization GO:0032879 104 0.031
larval development GO:0002164 2 0.031
eye development GO:0001654 277 0.031
hormone secretion GO:0046879 2 0.030
developmental pigmentation GO:0048066 48 0.030
reproduction GO:0000003 40 0.030
regulation of organ growth GO:0046620 3 0.030
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.029
cellular protein metabolic process GO:0044267 129 0.029
circadian sleep wake cycle sleep GO:0050802 1 0.029
response to oxygen containing compound GO:1901700 55 0.029
Zebrafish Mouse Rat
regulation of inflammatory response GO:0050727 2 0.029
positive regulation of cellular process GO:0048522 201 0.029
Rat
tissue remodeling GO:0048771 4 0.029
cellular response to endogenous stimulus GO:0071495 68 0.029
Mouse
regulation of bone remodeling GO:0046850 2 0.029
regulation of macromolecule biosynthetic process GO:0010556 225 0.027
positive regulation of cellular component biogenesis GO:0044089 3 0.027
regulation of multicellular organismal process GO:0051239 277 0.027
Mouse Rat
foregut morphogenesis GO:0007440 4 0.027
extrinsic apoptotic signaling pathway in absence of ligand GO:0097192 1 0.026
single organism metabolic process GO:0044710 217 0.026
female gonad development GO:0008585 4 0.026
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.026
regulation of cellular amino acid metabolic process GO:0006521 0 0.026
phosphate containing compound metabolic process GO:0006796 108 0.026
astrocyte differentiation GO:0048708 1 0.026
oxoacid metabolic process GO:0043436 31 0.025
response to uv GO:0009411 3 0.025
homeostatic process GO:0042592 142 0.025
methylation GO:0032259 22 0.025
positive regulation of protein metabolic process GO:0051247 23 0.025
cellular amino acid metabolic process GO:0006520 7 0.025
intracellular estrogen receptor signaling pathway GO:0030520 3 0.024
organic substance catabolic process GO:1901575 28 0.024
regulation of cellular amine metabolic process GO:0033238 0 0.024
neurological system process GO:0050877 62 0.024
b cell activation GO:0042113 2 0.024
regulation of tissue remodeling GO:0034103 2 0.024
negative regulation of feeding behavior GO:2000252 2 0.023
aromatic compound biosynthetic process GO:0019438 217 0.023
multi organism process GO:0051704 134 0.023
Rat
organonitrogen compound metabolic process GO:1901564 74 0.023
regulation of protein modification by small protein conjugation or removal GO:1903320 3 0.023
neuroblast proliferation GO:0007405 2 0.023
Rat
positive regulation of cell cycle GO:0045787 3 0.023
regulation of systemic arterial blood pressure GO:0003073 1 0.022
sensory perception of chemical stimulus GO:0007606 3 0.022
regeneration GO:0031099 91 0.022
odontogenesis of dentin containing tooth GO:0042475 1 0.022
dna modification GO:0006304 8 0.022
positive regulation of cell death GO:0010942 29 0.022
regulation of ph GO:0006885 3 0.022
membrane invagination GO:0010324 1 0.022
neuron projection development GO:0031175 180 0.022
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 68 0.021
death GO:0016265 121 0.021
Zebrafish Rat
positive regulation of transport GO:0051050 2 0.021
peptide transport GO:0015833 1 0.021
positive regulation of nucleobase containing compound metabolic process GO:0045935 69 0.021
response to decreased oxygen levels GO:0036293 25 0.021
transport GO:0006810 220 0.021
multicellular organismal homeostasis GO:0048871 29 0.021
negative regulation of metabolic process GO:0009892 86 0.021
absorption of visible light GO:0016038 2 0.021
stem cell division GO:0017145 1 0.020
embryonic hemopoiesis GO:0035162 53 0.020
sensory perception of light stimulus GO:0050953 19 0.020
light induced release of internally sequestered calcium ion GO:0008377 1 0.020
locomotor rhythm GO:0045475 3 0.020
embryonic skeletal joint morphogenesis GO:0060272 3 0.020
positive regulation of map kinase activity GO:0043406 3 0.020
regulation of signal transduction GO:0009966 225 0.020
developmental growth GO:0048589 166 0.019
Mouse
fin development GO:0033333 77 0.019
action potential GO:0001508 19 0.019
macromolecule biosynthetic process GO:0009059 227 0.019
reproductive process GO:0022414 40 0.019
Rat
single organism localization GO:1902578 225 0.019
cell projection organization GO:0030030 284 0.019
cellular pigmentation GO:0033059 30 0.019
Zebrafish
lipid localization GO:0010876 11 0.018
response to oxygen levels GO:0070482 25 0.018
epiboly GO:0090504 41 0.018
cellular component movement GO:0006928 335 0.018
myeloid cell development GO:0061515 32 0.018
wnt signaling pathway GO:0016055 80 0.018
positive regulation of cell communication GO:0010647 56 0.017
regulation of sequestering of calcium ion GO:0051282 4 0.017
protein modification process GO:0036211 100 0.017
positive regulation of carbohydrate metabolic process GO:0045913 1 0.017
cellular protein modification process GO:0006464 100 0.017
regulation of rna metabolic process GO:0051252 224 0.017
regulation of molecular function GO:0065009 70 0.017
apoptotic process GO:0006915 116 0.017
Zebrafish
regulation of growth rate GO:0040009 1 0.017
negative regulation of growth rate GO:0045967 1 0.017
negative regulation of macromolecule metabolic process GO:0010605 76 0.017
regulation of tube size GO:0035150 2 0.016
maintenance of location GO:0051235 4 0.016
lens fiber cell development GO:0070307 3 0.016
positive regulation of muscle tissue development GO:1901863 1 0.016
positive regulation of cellular biosynthetic process GO:0031328 68 0.016
Rat
ovarian follicle development GO:0001541 2 0.016
response to unfolded protein GO:0006986 2 0.016
regulation of endodermal cell fate specification GO:0042663 15 0.016
regulation of circadian rhythm GO:0042752 4 0.016
phosphorus metabolic process GO:0006793 109 0.015
regulation of i kappab kinase nf kappab signaling GO:0043122 4 0.015
smooth muscle contraction GO:0006939 2 0.015
bone remodeling GO:0046849 2 0.015
serotonin biosynthetic process GO:0042427 1 0.015
ribose phosphate metabolic process GO:0019693 27 0.015
regulation of rna biosynthetic process GO:2001141 213 0.015
positive regulation of secretion GO:0051047 1 0.015
purine nucleoside monophosphate catabolic process GO:0009128 4 0.015
negative regulation of blood circulation GO:1903523 2 0.015
cellular nitrogen compound biosynthetic process GO:0044271 218 0.015
regulation of protein complex assembly GO:0043254 3 0.014
protein targeting to nucleus GO:0044744 3 0.014
camera type eye morphogenesis GO:0048593 108 0.014
mapk cascade GO:0000165 18 0.014
gtp catabolic process GO:0006184 2 0.014
positive regulation of cellular catabolic process GO:0031331 3 0.014
regulation of cell death GO:0010941 103 0.014
Zebrafish Rat
startle response GO:0001964 4 0.014
regulation of cell communication GO:0010646 232 0.014
regulation of nucleic acid templated transcription GO:1903506 213 0.014
nucleobase containing compound metabolic process GO:0006139 274 0.014
rna metabolic process GO:0016070 219 0.014
positive regulation of secretion by cell GO:1903532 1 0.014
multicellular organismal water homeostasis GO:0050891 1 0.014
cell projection morphogenesis GO:0048858 244 0.013
positive regulation of signal transduction GO:0009967 56 0.013
response to hypoxia GO:0001666 25 0.013
anterior head development GO:0097065 2 0.013
cellular lipid metabolic process GO:0044255 36 0.013
response to organic substance GO:0010033 153 0.013
Zebrafish Mouse Rat
positive regulation of transcription dna templated GO:0045893 57 0.013
blood vessel development GO:0001568 246 0.013
regulation of neuron migration GO:2001222 2 0.013
regulation of skeletal muscle tissue development GO:0048641 4 0.013
regulation of cell differentiation GO:0045595 142 0.013
Rat
i kappab kinase nf kappab signaling GO:0007249 4 0.013
regulation of carbohydrate metabolic process GO:0006109 4 0.013
endocardial cushion morphogenesis GO:0003203 3 0.013
response to reactive oxygen species GO:0000302 5 0.013
developmental process involved in reproduction GO:0003006 27 0.013
kupffer s vesicle development GO:0070121 50 0.013
regulation of neurological system process GO:0031644 2 0.012
ear development GO:0043583 127 0.012
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.012
apical junction assembly GO:0043297 1 0.012
inner ear receptor cell fate commitment GO:0060120 4 0.012
neuropeptide signaling pathway GO:0007218 11 0.012
medial fin morphogenesis GO:0035141 14 0.012
cellular response to reactive oxygen species GO:0034614 2 0.012
positive regulation of peptidyl tyrosine phosphorylation GO:0050731 1 0.012
oxidation reduction process GO:0055114 41 0.012
regulation of neural precursor cell proliferation GO:2000177 3 0.012
epithelial cell differentiation GO:0030855 116 0.012
polarized epithelial cell differentiation GO:0030859 4 0.012
cell migration GO:0016477 237 0.012
negative regulation of cyclase activity GO:0031280 6 0.012
positive regulation of cell development GO:0010720 25 0.012
Rat
cellular monovalent inorganic cation homeostasis GO:0030004 2 0.012
purine ribonucleoside monophosphate catabolic process GO:0009169 4 0.012
gland development GO:0048732 143 0.012
regulation of hydrolase activity GO:0051336 28 0.012
positive regulation of extrinsic apoptotic signaling pathway GO:2001238 1 0.012
positive regulation of neural retina development GO:0061075 1 0.012
nucleocytoplasmic transport GO:0006913 4 0.012
positive regulation of developmental process GO:0051094 50 0.012
Mouse Rat
regulation of macromolecule metabolic process GO:0060255 317 0.011
lens morphogenesis in camera type eye GO:0002089 7 0.011
biosynthetic process GO:0009058 294 0.011
Rat
nucleoside phosphate metabolic process GO:0006753 28 0.011
positive regulation of erk1 and erk2 cascade GO:0070374 2 0.011
response to growth factor GO:0070848 39 0.011
inositol phosphate metabolic process GO:0043647 1 0.011
carbohydrate homeostasis GO:0033500 1 0.011
positive regulation of protein complex assembly GO:0031334 2 0.011
melanosome localization GO:0032400 21 0.011
ovulation cycle GO:0042698 2 0.011
caudal fin morphogenesis GO:0035143 7 0.011
protein import GO:0017038 3 0.011
nucleoside monophosphate catabolic process GO:0009125 4 0.011
pigment granule localization GO:0051875 25 0.011
Zebrafish
endoplasmic reticulum unfolded protein response GO:0030968 2 0.011
muscle organ development GO:0007517 101 0.011
glucocorticoid metabolic process GO:0008211 2 0.011
apoptotic signaling pathway GO:0097190 23 0.011
modification dependent macromolecule catabolic process GO:0043632 3 0.011
regulation of blood vessel size GO:0050880 2 0.011
activation of mapk activity GO:0000187 3 0.011
regulation of cellular protein metabolic process GO:0032268 52 0.010
positive regulation of rna metabolic process GO:0051254 59 0.010
mesenchymal cell proliferation GO:0010463 1 0.010
regulation of transport GO:0051049 45 0.010
endocardial cell differentiation GO:0060956 5 0.010
cardiac muscle cell contraction GO:0086003 1 0.010
response to drug GO:0042493 3 0.010
cellular component assembly GO:0022607 170 0.010
sensory organ morphogenesis GO:0090596 200 0.010
phosphorylation GO:0016310 69 0.010
organelle localization GO:0051640 49 0.010
Zebrafish
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 20 0.010

gh1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.116
nervous system disease DOID:863 0 0.010