Danio rerio

0 known processes

ghrb

growth hormone receptor b

(Aliases: ghr.b)

ghrb biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
branched chain amino acid metabolic process GO:0009081 1 0.950
Mouse
alpha amino acid metabolic process GO:1901605 3 0.850
Mouse
cellular modified amino acid metabolic process GO:0006575 3 0.469
Mouse
response to glucocorticoid GO:0051384 1 0.412
Rat
response to organic cyclic compound GO:0014070 51 0.411
Human Rat
response to alkaloid GO:0043279 2 0.384
Rat
multicellular organismal metabolic process GO:0044236 2 0.349
Human
response to food GO:0032094 1 0.309
Rat
response to corticosteroid GO:0031960 1 0.302
Rat
response to external stimulus GO:0009605 264 0.277
Rat
insulin like growth factor receptor signaling pathway GO:0048009 4 0.277
Human
cartilage development GO:0051216 96 0.261
Rat
skeletal system development GO:0001501 181 0.255
Rat
regulation of multicellular organism growth GO:0040014 4 0.231
Human Mouse
taurine metabolic process GO:0019530 1 0.226
Mouse
cellular amino acid metabolic process GO:0006520 7 0.219
Mouse
carboxylic acid metabolic process GO:0019752 22 0.209
Mouse
positive regulation of map kinase activity GO:0043406 3 0.198
Rat
response to estrogen GO:0043627 27 0.194
Human
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.193
immune system process GO:0002376 241 0.183
response to steroid hormone GO:0048545 35 0.183
Human Rat
cellular amide metabolic process GO:0043603 4 0.182
Mouse
positive regulation of jak stat cascade GO:0046427 2 0.176
Rat
cellular amine metabolic process GO:0044106 2 0.148
regulation of primary metabolic process GO:0080090 311 0.142
Mouse Rat
oxoacid metabolic process GO:0043436 31 0.132
Mouse
connective tissue development GO:0061448 99 0.128
Rat
hormone mediated signaling pathway GO:0009755 9 0.121
Rat
aging GO:0007568 2 0.120
embryonic organ development GO:0048568 381 0.119
central nervous system development GO:0007417 387 0.118
regulation of cellular amine metabolic process GO:0033238 0 0.115
amine metabolic process GO:0009308 2 0.114
regulation of cell differentiation GO:0045595 142 0.106
Rat
organonitrogen compound metabolic process GO:1901564 74 0.106
Mouse
cellular response to external stimulus GO:0071496 2 0.103
heart development GO:0007507 313 0.091
response to chemical GO:0042221 320 0.090
Human Mouse Rat
embryonic organ morphogenesis GO:0048562 274 0.088
organelle organization GO:0006996 227 0.083
response to nutrient GO:0007584 3 0.081
locomotion GO:0040011 313 0.079
cellular response to nutrient levels GO:0031669 2 0.079
regulation of cellular amino acid metabolic process GO:0006521 0 0.078
regulation of jak stat cascade GO:0046425 3 0.078
Rat
cell surface receptor signaling pathway GO:0007166 325 0.078
Human Mouse Rat
cellular protein metabolic process GO:0044267 129 0.077
Mouse Rat
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.076
Mouse
activation of mapk activity GO:0000187 3 0.076
Rat
regulation of macromolecule metabolic process GO:0060255 317 0.074
Mouse Rat
organic acid metabolic process GO:0006082 31 0.071
Mouse
cellular response to extracellular stimulus GO:0031668 2 0.070
response to hormone GO:0009725 48 0.069
Human Mouse Rat
generation of neurons GO:0048699 385 0.069
receptor internalization GO:0031623 2 0.069
Human
response to vitamin GO:0033273 3 0.068
cellular macromolecule metabolic process GO:0044260 391 0.067
Human Mouse Rat
response to ketone GO:1901654 1 0.065
cellular response to hormone stimulus GO:0032870 39 0.064
Human Mouse Rat
regulation of cellular ketone metabolic process GO:0010565 7 0.062
neuron differentiation GO:0030182 353 0.060
cellular response to estrogen stimulus GO:0071391 24 0.057
single organism transport GO:0044765 206 0.057
Human
sensory organ morphogenesis GO:0090596 200 0.056
establishment of localization GO:0051234 244 0.055
Human
muscle structure development GO:0061061 196 0.055
single organism metabolic process GO:0044710 217 0.054
Human Mouse Rat
hemopoiesis GO:0030097 183 0.054
cellular response to organic cyclic compound GO:0071407 38 0.054
response to endogenous stimulus GO:0009719 83 0.053
Human Mouse Rat
heterocycle metabolic process GO:0046483 290 0.052
Mouse
cellular nitrogen compound metabolic process GO:0034641 290 0.052
Mouse
liver development GO:0001889 96 0.052
hindbrain development GO:0030902 91 0.049
cell motility GO:0048870 244 0.048
negative regulation of cellular process GO:0048523 283 0.047
Rat
ear development GO:0043583 127 0.047
response to abiotic stimulus GO:0009628 122 0.047
regulation of cell communication GO:0010646 232 0.046
Rat
inner ear development GO:0048839 126 0.046
response to lipid GO:0033993 60 0.046
Human Rat
system process GO:0003008 185 0.046
regulation of response to stimulus GO:0048583 269 0.045
Rat
nucleobase containing compound biosynthetic process GO:0034654 205 0.043
response to estradiol GO:0032355 6 0.043
Human
response to glucose GO:0009749 3 0.043
regulation of cellular metabolic process GO:0031323 320 0.042
Mouse Rat
erythrocyte homeostasis GO:0034101 55 0.042
chordate embryonic development GO:0043009 271 0.042
single organism localization GO:1902578 225 0.041
Human
single organism organelle organization GO:1902589 199 0.041
muscle cell differentiation GO:0042692 139 0.041
cellular response to organic substance GO:0071310 105 0.040
Human Mouse Rat
larval development GO:0002164 2 0.040
pancreas development GO:0031016 84 0.039
response to stress GO:0006950 263 0.039
cellular response to chemical stimulus GO:0070887 157 0.038
Human Mouse Rat
erythrocyte differentiation GO:0030218 54 0.038
response to nutrient levels GO:0031667 10 0.038
Rat
developmental growth GO:0048589 166 0.038
Human Mouse
transport GO:0006810 220 0.037
Human
immune system development GO:0002520 191 0.036
cell morphogenesis GO:0000902 289 0.036
mitotic cell cycle GO:0000278 64 0.036
myeloid cell differentiation GO:0030099 86 0.035
regulation of protein metabolic process GO:0051246 56 0.035
Mouse Rat
heart morphogenesis GO:0003007 156 0.035
cellular component morphogenesis GO:0032989 336 0.035
peptidyl tyrosine modification GO:0018212 5 0.035
Mouse Rat
sensory organ development GO:0007423 393 0.034
cell projection organization GO:0030030 284 0.034
cellular response to steroid hormone stimulus GO:0071383 31 0.034
brain development GO:0007420 293 0.034
protein activation cascade GO:0072376 6 0.033
cellular lipid metabolic process GO:0044255 36 0.033
Mouse
cellular protein modification process GO:0006464 100 0.032
Mouse Rat
regulation of developmental process GO:0050793 247 0.032
Human Mouse Rat
embryo development ending in birth or egg hatching GO:0009792 271 0.031
response to monosaccharide GO:0034284 3 0.031
stem cell maintenance GO:0019827 4 0.031
cellular response to starvation GO:0009267 1 0.031
intracellular signal transduction GO:0035556 85 0.031
Rat
multicellular organism growth GO:0035264 4 0.030
Human Mouse
regulation of nervous system development GO:0051960 90 0.030
somitogenesis GO:0001756 87 0.030
regulation of multicellular organismal process GO:0051239 277 0.029
Human Mouse
specification of symmetry GO:0009799 204 0.029
positive regulation of biological process GO:0048518 253 0.028
Human Mouse Rat
response to organic substance GO:0010033 153 0.028
Human Mouse Rat
cranial nerve development GO:0021545 42 0.028
positive regulation of signal transduction GO:0009967 56 0.028
Rat
regulation of rna biosynthetic process GO:2001141 213 0.027
regulation of metabolic process GO:0019222 359 0.027
Mouse Rat
regulation of hormone secretion GO:0046883 2 0.027
centrosome organization GO:0051297 1 0.027
regulation of biological quality GO:0065008 263 0.027
morphogenesis of an epithelium GO:0002009 333 0.026
negative regulation of cell death GO:0060548 60 0.026
Rat
regulation of cell activation GO:0050865 1 0.025
cellular ketone metabolic process GO:0042180 11 0.025
protein modification process GO:0036211 100 0.025
Mouse Rat
regulation of carbohydrate metabolic process GO:0006109 4 0.025
organic acid catabolic process GO:0016054 3 0.025
guanosine containing compound metabolic process GO:1901068 4 0.025
glucose import GO:0046323 2 0.024
cognition GO:0050890 1 0.024
regulation of signaling GO:0023051 235 0.024
Rat
adult behavior GO:0030534 2 0.024
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.024
gland development GO:0048732 143 0.024
response to extracellular stimulus GO:0009991 10 0.023
Rat
positive regulation of cellular process GO:0048522 201 0.023
Mouse Rat
regulation of catalytic activity GO:0050790 55 0.023
Rat
negative regulation of leukocyte differentiation GO:1902106 1 0.023
cellular extravasation GO:0045123 1 0.023
phosphorylation GO:0016310 69 0.023
Mouse Rat
striated muscle cell differentiation GO:0051146 129 0.022
cellular carbohydrate metabolic process GO:0044262 4 0.022
maintenance of location GO:0051235 4 0.022
positive regulation of cell cycle GO:0045787 3 0.022
camera type eye development GO:0043010 222 0.022
establishment of protein localization to plasma membrane GO:0090002 1 0.022
angiogenesis GO:0001525 158 0.022
small molecule catabolic process GO:0044282 3 0.022
determination of heart left right asymmetry GO:0061371 117 0.022
regulation of epithelial cell proliferation GO:0050678 3 0.021
cellular amino acid biosynthetic process GO:0008652 2 0.021
eye development GO:0001654 277 0.021
development of primary female sexual characteristics GO:0046545 4 0.021
signal transduction GO:0007165 455 0.021
Human Mouse Rat
protein metabolic process GO:0019538 183 0.021
Mouse Rat
response to drug GO:0042493 3 0.021
positive regulation of cell activation GO:0050867 1 0.021
hematopoietic or lymphoid organ development GO:0048534 191 0.021
positive regulation of response to stimulus GO:0048584 80 0.021
Rat
cell substrate adhesion GO:0031589 4 0.021
cartilage development involved in endochondral bone morphogenesis GO:0060351 8 0.021
Rat
blood coagulation fibrin clot formation GO:0072378 3 0.021
blood vessel development GO:0001568 246 0.020
g1 s transition of mitotic cell cycle GO:0000082 1 0.020
embryonic heart tube development GO:0035050 133 0.020
microtubule organizing center organization GO:0031023 1 0.020
centrosome cycle GO:0007098 1 0.019
epithelial tube morphogenesis GO:0060562 148 0.019
response to hexose GO:0009746 3 0.019
developmental growth involved in morphogenesis GO:0060560 86 0.019
positive regulation of cell division GO:0051781 2 0.019
regulation of cellular carbohydrate metabolic process GO:0010675 4 0.019
cell migration GO:0016477 237 0.019
cell matrix adhesion GO:0007160 4 0.019
neuron projection development GO:0031175 180 0.018
regulation of hormone levels GO:0010817 21 0.018
nitrogen compound metabolic process GO:0006807 319 0.018
Mouse
neurological system process GO:0050877 62 0.018
response to carbohydrate GO:0009743 3 0.018
mesoderm development GO:0007498 88 0.018
macromolecule modification GO:0043412 111 0.018
Mouse Rat
eye morphogenesis GO:0048592 144 0.018
pericardium development GO:0060039 1 0.017
small molecule metabolic process GO:0044281 77 0.017
Mouse
embryonic skeletal system development GO:0048706 97 0.017
oocyte maturation GO:0001556 4 0.017
regulation of intracellular signal transduction GO:1902531 57 0.017
Rat
negative regulation of autophagy GO:0010507 1 0.017
cellular nitrogen compound biosynthetic process GO:0044271 218 0.017
cellular response to hypoxia GO:0071456 1 0.017
peptidyl tyrosine phosphorylation GO:0018108 5 0.017
Mouse Rat
somatic muscle development GO:0007525 4 0.017
positive regulation of cell differentiation GO:0045597 30 0.017
Rat
regulation of dna replication GO:0006275 3 0.017
peptide transport GO:0015833 1 0.017
positive regulation of cell communication GO:0010647 56 0.016
Rat
autophagy GO:0006914 4 0.016
death GO:0016265 121 0.016
Rat
cellular response to oxygen levels GO:0071453 1 0.016
lipid metabolic process GO:0006629 52 0.016
Mouse
negative regulation of biological process GO:0048519 304 0.016
Rat
regulation of production of molecular mediator of immune response GO:0002700 1 0.016
head development GO:0060322 303 0.016
carboxylic acid catabolic process GO:0046395 3 0.016
establishment of blood brain barrier GO:0060856 2 0.016
carbohydrate biosynthetic process GO:0016051 1 0.016
sprouting angiogenesis GO:0002040 53 0.015
bone morphogenesis GO:0060349 11 0.015
Rat
muscle cell migration GO:0014812 4 0.015
hormone transport GO:0009914 2 0.015
lymphocyte proliferation GO:0046651 1 0.015
cell projection morphogenesis GO:0048858 244 0.015
hormone secretion GO:0046879 2 0.015
positive regulation of catabolic process GO:0009896 4 0.015
cell part morphogenesis GO:0032990 246 0.015
digestive system development GO:0055123 289 0.015
energy reserve metabolic process GO:0006112 2 0.015
positive regulation of gliogenesis GO:0014015 2 0.015
enzyme linked receptor protein signaling pathway GO:0007167 106 0.015
Human Mouse Rat
striated muscle cell development GO:0055002 108 0.015
protein o linked glycosylation GO:0006493 4 0.015
regeneration GO:0031099 91 0.015
neuron development GO:0048666 262 0.015
response to light stimulus GO:0009416 46 0.015
negative regulation of cell communication GO:0010648 96 0.014
astrocyte differentiation GO:0048708 1 0.014
regulation of transferase activity GO:0051338 16 0.014
Rat
apoptotic process GO:0006915 116 0.014
response to radiation GO:0009314 51 0.014
blood vessel morphogenesis GO:0048514 216 0.014
regulation of cell death GO:0010941 103 0.014
Rat
monocyte differentiation GO:0030224 2 0.014
regulation of inflammatory response GO:0050727 2 0.014
spinal cord development GO:0021510 46 0.014
localization of cell GO:0051674 244 0.014
axonogenesis GO:0007409 152 0.014
homeostasis of number of cells GO:0048872 62 0.014
developmental cell growth GO:0048588 52 0.014
behavior GO:0007610 74 0.014
tube morphogenesis GO:0035239 349 0.014
extrinsic apoptotic signaling pathway via death domain receptors GO:0008625 1 0.014
monovalent inorganic cation transport GO:0015672 42 0.014
growth GO:0040007 174 0.014
Human Mouse
cellular response to radiation GO:0071478 4 0.014
cellular component movement GO:0006928 335 0.013
cellular component assembly involved in morphogenesis GO:0010927 107 0.013
transmembrane transport GO:0055085 120 0.013
negative regulation of feeding behavior GO:2000252 2 0.013
cation transmembrane transport GO:0098655 65 0.013
cellular response to lipid GO:0071396 39 0.013
lateral line system development GO:0048925 76 0.013
regulation of rho protein signal transduction GO:0035023 2 0.013
ventral spinal cord development GO:0021517 35 0.013
sensory system development GO:0048880 76 0.013
organic cyclic compound metabolic process GO:1901360 301 0.013
Mouse
cell cycle g1 s phase transition GO:0044843 1 0.013
positive regulation of cellular amine metabolic process GO:0033240 0 0.013
phosphatidylinositol 3 kinase signaling GO:0014065 2 0.013
aromatic compound biosynthetic process GO:0019438 217 0.013
negative regulation of epithelial cell proliferation GO:0050680 1 0.013
receptor metabolic process GO:0043112 6 0.013
Human
purine ribonucleoside monophosphate catabolic process GO:0009169 4 0.013
vasculature development GO:0001944 278 0.013
positive regulation of peptidyl tyrosine phosphorylation GO:0050731 1 0.013
Mouse
central nervous system neuron differentiation GO:0021953 74 0.013
ribonucleoside monophosphate catabolic process GO:0009158 4 0.013
antimicrobial humoral response GO:0019730 2 0.013
hepaticobiliary system development GO:0061008 98 0.013
germ line stem cell maintenance GO:0030718 2 0.013
forebrain development GO:0030900 96 0.013
negative regulation of cell migration GO:0030336 17 0.013
cellular lipid catabolic process GO:0044242 3 0.013
leukocyte proliferation GO:0070661 1 0.012
lateral line development GO:0048882 66 0.012
positive regulation of cellular catabolic process GO:0031331 3 0.012
post embryonic organ development GO:0048569 4 0.012
tissue regeneration GO:0042246 74 0.012
determination of left right symmetry GO:0007368 179 0.012
embryonic hemopoiesis GO:0035162 53 0.012
negative regulation of small gtpase mediated signal transduction GO:0051058 1 0.012
gastrulation GO:0007369 208 0.012
embryonic skeletal system morphogenesis GO:0048704 93 0.012
membrane lipid biosynthetic process GO:0046467 2 0.012
regulation of growth GO:0040008 42 0.012
Human Mouse
inositol lipid mediated signaling GO:0048017 2 0.012
cellular response to oxygen containing compound GO:1901701 20 0.012
Human Mouse Rat
purine nucleoside monophosphate catabolic process GO:0009128 4 0.012
negative regulation of myeloid leukocyte differentiation GO:0002762 1 0.012
muscle cell development GO:0055001 115 0.012
gtp metabolic process GO:0046039 4 0.012
axon guidance GO:0007411 86 0.012
cell morphogenesis involved in differentiation GO:0000904 195 0.012
regulation of autophagy GO:0010506 3 0.012
regulation of localization GO:0032879 104 0.012
negative regulation of locomotion GO:0040013 18 0.012
phenol containing compound biosynthetic process GO:0046189 4 0.012
negative regulation of dna metabolic process GO:0051053 4 0.012
protein localization to plasma membrane GO:0072659 1 0.011
single organism nuclear import GO:1902593 3 0.011
negative regulation of dna replication GO:0008156 2 0.011
stem cell development GO:0048864 82 0.011
cellular response to decreased oxygen levels GO:0036294 1 0.011
apical junction assembly GO:0043297 1 0.011
positive regulation of cellular metabolic process GO:0031325 94 0.011
Mouse Rat
type b pancreatic cell proliferation GO:0044342 1 0.011
positive regulation of catalytic activity GO:0043085 25 0.011
Rat
collagen metabolic process GO:0032963 2 0.011
macrophage differentiation GO:0030225 7 0.011
myeloid leukocyte differentiation GO:0002573 15 0.011
extrinsic apoptotic signaling pathway GO:0097191 3 0.011
regulation of multicellular organismal development GO:2000026 223 0.011
regulation of kinase activity GO:0043549 15 0.011
Rat
cellular response to peptide hormone stimulus GO:0071375 5 0.011
Human Mouse Rat
protein phosphorylation GO:0006468 47 0.011
Mouse Rat
macromolecular complex subunit organization GO:0043933 74 0.011
cellular response to fatty acid GO:0071398 3 0.011
regulation of erythrocyte differentiation GO:0045646 2 0.011
positive regulation of cellular protein metabolic process GO:0032270 22 0.011
Mouse Rat
cation transport GO:0006812 81 0.011
female gonad development GO:0008585 4 0.011
neurotransmitter transport GO:0006836 2 0.011
erythrocyte development GO:0048821 24 0.011
response to wounding GO:0009611 116 0.011
regulation of programmed cell death GO:0043067 101 0.010
neutrophil differentiation GO:0030223 6 0.010
regulation of immune system process GO:0002682 34 0.010
regulation of cell substrate adhesion GO:0010810 1 0.010
regulation of cell shape GO:0008360 1 0.010
multicellular organismal response to stress GO:0033555 2 0.010
pericardium morphogenesis GO:0003344 1 0.010
cellular macromolecule biosynthetic process GO:0034645 224 0.010
macromolecule biosynthetic process GO:0009059 227 0.010
homeostatic process GO:0042592 142 0.010
negative regulation of ras protein signal transduction GO:0046580 1 0.010
single organismal cell cell adhesion GO:0016337 29 0.010
neuron projection extension GO:1990138 45 0.010
regulation of response to biotic stimulus GO:0002831 2 0.010
fatty acid transport GO:0015908 1 0.010
regulation of stem cell differentiation GO:2000736 4 0.010
negative regulation of myeloid cell differentiation GO:0045638 1 0.010
dna templated transcription initiation GO:0006352 1 0.010
cytoskeleton organization GO:0007010 96 0.010
positive regulation of stress activated protein kinase signaling cascade GO:0070304 3 0.010
hormone metabolic process GO:0042445 19 0.010
monocarboxylic acid metabolic process GO:0032787 17 0.010
Mouse

ghrb disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 0 0.328
Human
inherited metabolic disorder DOID:655 0 0.328
Human
lipid metabolism disorder DOID:3146 0 0.156
Human
disease of anatomical entity DOID:7 0 0.019
nervous system disease DOID:863 0 0.019
sensory system disease DOID:0050155 0 0.011
eye and adnexa disease DOID:1492 0 0.011
eye disease DOID:5614 0 0.011