Danio rerio

187 known processes

gli1

GLI-Kruppel family member 1

gli1 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
diencephalon development GO:0021536 58 1.000
cell motility GO:0048870 244 1.000
Worm
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.999
cell surface receptor signaling pathway GO:0007166 325 0.999
regulation of gene expression GO:0010468 265 0.999
regulation of rna biosynthetic process GO:2001141 213 0.999
regulation of rna metabolic process GO:0051252 224 0.999
cellular nitrogen compound biosynthetic process GO:0044271 218 0.998
rna metabolic process GO:0016070 219 0.998
central nervous system neuron differentiation GO:0021953 74 0.998
cell projection organization GO:0030030 284 0.997
transcription dna templated GO:0006351 181 0.997
embryo development ending in birth or egg hatching GO:0009792 271 0.997
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.997
regionalization GO:0003002 274 0.997
nucleic acid templated transcription GO:0097659 181 0.997
generation of neurons GO:0048699 385 0.997
nucleobase containing compound biosynthetic process GO:0034654 205 0.997
aromatic compound biosynthetic process GO:0019438 217 0.997
regulation of biosynthetic process GO:0009889 250 0.997
regulation of macromolecule biosynthetic process GO:0010556 225 0.996
axon guidance GO:0007411 86 0.996
somitogenesis GO:0001756 87 0.996
Zebrafish
cellular component morphogenesis GO:0032989 336 0.995
regulation of multicellular organismal development GO:2000026 223 0.995
regulation of metabolic process GO:0019222 359 0.995
organic cyclic compound biosynthetic process GO:1901362 223 0.995
regulation of nucleic acid templated transcription GO:1903506 213 0.995
negative regulation of cellular process GO:0048523 283 0.995
Human Worm
neuron projection guidance GO:0097485 86 0.995
neuron projection development GO:0031175 180 0.993
nucleobase containing compound metabolic process GO:0006139 274 0.993
cell morphogenesis involved in differentiation GO:0000904 195 0.991
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.990
regulation of macromolecule metabolic process GO:0060255 317 0.990
forebrain development GO:0030900 96 0.989
macromolecule biosynthetic process GO:0009059 227 0.989
digestive tract development GO:0048565 265 0.987
Zebrafish
rna biosynthetic process GO:0032774 181 0.987
regulation of response to stimulus GO:0048583 269 0.987
heterocycle biosynthetic process GO:0018130 215 0.987
regulation of nervous system development GO:0051960 90 0.979
organic substance biosynthetic process GO:1901576 289 0.979
chordate embryonic development GO:0043009 271 0.977
digestive tract morphogenesis GO:0048546 231 0.975
Zebrafish
positive regulation of epithelial cell differentiation GO:0030858 2 0.975
Fly
axonogenesis GO:0007409 152 0.975
embryonic camera type eye development GO:0031076 29 0.974
cellular macromolecule biosynthetic process GO:0034645 224 0.973
gene expression GO:0010467 252 0.973
mesoderm development GO:0007498 88 0.972
cellular biosynthetic process GO:0044249 286 0.971
regulation of nitrogen compound metabolic process GO:0051171 251 0.971
regulation of primary metabolic process GO:0080090 311 0.969
locomotion GO:0040011 313 0.969
cellular nitrogen compound metabolic process GO:0034641 290 0.969
diencephalon morphogenesis GO:0048852 5 0.968
somite development GO:0061053 96 0.967
Zebrafish
bmp signaling pathway GO:0030509 52 0.961
head development GO:0060322 303 0.961
cell fate commitment GO:0045165 99 0.961
smoothened signaling pathway GO:0007224 30 0.960
cellular macromolecule metabolic process GO:0044260 391 0.959
positive regulation of biosynthetic process GO:0009891 68 0.958
Human Mouse Worm Fly
cell morphogenesis GO:0000902 289 0.956
neural tube development GO:0021915 62 0.956
regulation of cellular metabolic process GO:0031323 320 0.955
striated muscle cell differentiation GO:0051146 129 0.955
Zebrafish
positive regulation of transcription dna templated GO:0045893 57 0.954
Human Mouse Worm Fly
sensory organ morphogenesis GO:0090596 200 0.951
Fly
biosynthetic process GO:0009058 294 0.949
organic cyclic compound metabolic process GO:1901360 301 0.946
floor plate morphogenesis GO:0033505 12 0.946
gland development GO:0048732 143 0.946
regulation of cellular biosynthetic process GO:0031326 245 0.945
localization of cell GO:0051674 244 0.944
Worm
neuron differentiation GO:0030182 353 0.943
floor plate formation GO:0021508 12 0.942
retinal ganglion cell axon guidance GO:0031290 35 0.942
neural tube patterning GO:0021532 33 0.941
muscle organ development GO:0007517 101 0.940
Zebrafish
chemotaxis GO:0006935 104 0.940
anterior posterior pattern specification GO:0009952 152 0.936
Zebrafish Fly
regulation of stem cell proliferation GO:0072091 2 0.936
positive regulation of rna metabolic process GO:0051254 59 0.935
Human Mouse Worm Fly
eye morphogenesis GO:0048592 144 0.932
Fly
nitrogen compound metabolic process GO:0006807 319 0.929
neuron development GO:0048666 262 0.929
regulation of signal transduction GO:0009966 225 0.929
negative regulation of rna metabolic process GO:0051253 48 0.926
Worm
gall bladder development GO:0061010 1 0.924
digestive system development GO:0055123 289 0.924
Zebrafish
nucleic acid metabolic process GO:0090304 244 0.922
segmentation GO:0035282 97 0.919
Zebrafish Fly
axon development GO:0061564 166 0.916
cell projection morphogenesis GO:0048858 244 0.915
taxis GO:0042330 109 0.908
stem cell development GO:0048864 82 0.907
positive regulation of muscle organ development GO:0048636 1 0.906
adenohypophysis development GO:0021984 15 0.906
appendage morphogenesis GO:0035107 56 0.903
brain development GO:0007420 293 0.902
response to external stimulus GO:0009605 264 0.902
bmp signaling pathway involved in heart development GO:0061312 15 0.900
muscle structure development GO:0061061 196 0.900
spinal cord patterning GO:0021511 6 0.899
regulation of cell development GO:0060284 100 0.898
proximal distal pattern formation GO:0009954 1 0.896
Mouse
muscle tissue development GO:0060537 110 0.895
eye development GO:0001654 277 0.894
Fly
negative regulation of anterior neural cell fate commitment of the neural plate GO:0022001 1 0.893
central nervous system projection neuron axonogenesis GO:0021952 15 0.890
spinal cord development GO:0021510 46 0.885
transcription from rna polymerase ii promoter GO:0006366 80 0.882
Human Mouse Worm Fly
muscle cell differentiation GO:0042692 139 0.881
positive regulation of macromolecule metabolic process GO:0010604 93 0.878
Human Mouse Worm Fly
cell adhesion GO:0007155 40 0.872
kidney development GO:0001822 92 0.869
Zebrafish
positive regulation of transcription from rna polymerase ii promoter GO:0045944 22 0.863
Human Mouse Worm Fly
mesoderm morphogenesis GO:0048332 51 0.855
forebrain neuron development GO:0021884 7 0.853
positive regulation of cellular metabolic process GO:0031325 94 0.851
Human Mouse Worm Fly
cell fate commitment involved in formation of primary germ layer GO:0060795 26 0.850
regulation of mesodermal cell fate specification GO:0042661 9 0.846
regeneration GO:0031099 91 0.842
mesodermal cell differentiation GO:0048333 21 0.841
cellular component movement GO:0006928 335 0.834
pituitary gland development GO:0021983 16 0.833
cell part morphogenesis GO:0032990 246 0.829
multicellular organismal reproductive process GO:0048609 35 0.828
Mouse Worm Fly
negative regulation of cell communication GO:0010648 96 0.827
Human
positive regulation of rna biosynthetic process GO:1902680 57 0.826
Human Mouse Worm Fly
camera type eye development GO:0043010 222 0.821
rostrocaudal neural tube patterning GO:0021903 29 0.820
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 50 0.817
positive regulation of nucleobase containing compound metabolic process GO:0045935 69 0.813
Human Mouse Worm Fly
positive regulation of multicellular organismal process GO:0051240 52 0.813
Mouse
determination of bilateral symmetry GO:0009855 204 0.812
mesodermal cell fate specification GO:0007501 12 0.804
ventral midline development GO:0007418 13 0.803
ear development GO:0043583 127 0.802
positive regulation of cellular process GO:0048522 201 0.800
positive regulation of metabolic process GO:0009893 108 0.800
Human Mouse Worm Fly
gastrulation GO:0007369 208 0.798
regulation of neuron differentiation GO:0045664 56 0.788
sexual reproduction GO:0019953 36 0.787
Mouse Worm Fly
apoptotic process GO:0006915 116 0.786
Worm
regulation of signaling GO:0023051 235 0.783
embryonic limb morphogenesis GO:0030326 2 0.782
negative regulation of neurogenesis GO:0050768 20 0.781
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 68 0.780
positive regulation of cell differentiation GO:0045597 30 0.779
Fly
positive regulation of gene expression GO:0010628 71 0.779
Human Mouse Worm Fly
regulation of inner ear receptor cell differentiation GO:2000980 1 0.778
epidermal cell differentiation GO:0009913 36 0.777
Human
muscle fiber development GO:0048747 52 0.777
response to chemical GO:0042221 320 0.773
negative regulation of multicellular organismal process GO:0051241 69 0.771
negative regulation of anterior neural cell fate commitment of the neural plate by wnt signaling pathway GO:0022002 1 0.771
positive regulation of developmental process GO:0051094 50 0.765
Mouse Fly
response to stress GO:0006950 263 0.760
signal transduction GO:0007165 455 0.759
negative regulation of signal transduction GO:0009968 94 0.752
Human
blood vessel morphogenesis GO:0048514 216 0.745
hypophysis morphogenesis GO:0048850 5 0.743
dorsal ventral pattern formation GO:0009953 125 0.743
primary neural tube formation GO:0014020 1 0.742
gamete generation GO:0007276 33 0.742
Mouse Worm Fly
positive regulation of cell communication GO:0010647 56 0.739
stem cell maintenance GO:0019827 4 0.737
negative regulation of cellular macromolecule biosynthetic process GO:2000113 48 0.737
Worm
regulation of organ growth GO:0046620 3 0.737
negative regulation of gene expression GO:0010629 65 0.736
Worm
wnt signaling pathway involved in digestive tract morphogenesis GO:0044333 4 0.736
camera type eye photoreceptor cell differentiation GO:0060219 19 0.730
positive regulation of cellular biosynthetic process GO:0031328 68 0.728
Human Mouse Worm Fly
regulation of transcription dna templated GO:0006355 213 0.722
glial cell differentiation GO:0010001 42 0.722
brain morphogenesis GO:0048854 18 0.715
glial cell migration GO:0008347 3 0.715
negative regulation of signaling GO:0023057 96 0.713
Human
cell fate specification GO:0001708 68 0.711
multicellular organism reproduction GO:0032504 35 0.711
Mouse Worm Fly
cytoskeleton organization GO:0007010 96 0.711
Worm
positive regulation of mesenchymal cell proliferation GO:0002053 1 0.710
sensory organ development GO:0007423 393 0.703
Fly
developmental growth involved in morphogenesis GO:0060560 86 0.702
notochord development GO:0030903 54 0.695
Mouse
heart jogging GO:0003146 40 0.693
regulation of endodermal cell fate specification GO:0042663 15 0.692
endocrine system development GO:0035270 65 0.691
programmed cell death GO:0012501 119 0.690
Worm
regulation of transcription from rna polymerase ii promoter involved in determination of left right symmetry GO:1900094 17 0.688
enzyme linked receptor protein signaling pathway GO:0007167 106 0.688
embryonic cranial skeleton morphogenesis GO:0048701 90 0.685
negative regulation of cell fate commitment GO:0010454 13 0.683
posterior lateral line system development GO:0048915 46 0.683
embryonic skeletal system development GO:0048706 97 0.682
system process GO:0003008 185 0.681
Zebrafish
skeletal muscle organ development GO:0060538 78 0.674
regulation of neural precursor cell proliferation GO:2000177 3 0.673
Mouse
negative regulation of nucleic acid templated transcription GO:1903507 45 0.673
Worm
thrombocyte differentiation GO:0002574 4 0.673
negative regulation of macromolecule metabolic process GO:0010605 76 0.669
Worm
neuron fate commitment GO:0048663 26 0.668
neuron projection morphogenesis GO:0048812 161 0.663
eye field cell fate commitment involved in camera type eye formation GO:0060898 3 0.660
epithelial cell differentiation GO:0030855 116 0.660
Human Fly
heterocycle metabolic process GO:0046483 290 0.658
positive regulation of nucleic acid templated transcription GO:1903508 57 0.655
Human Mouse Worm Fly
telencephalon development GO:0021537 14 0.652
macromolecular complex subunit organization GO:0043933 74 0.651
Worm
forebrain generation of neurons GO:0021872 14 0.650
regulation of axonogenesis GO:0050770 32 0.647
neuron projection extension GO:1990138 45 0.646
neural plate development GO:0001840 10 0.644
regulation of anatomical structure morphogenesis GO:0022603 130 0.641
positive regulation of striated muscle tissue development GO:0045844 1 0.640
striated muscle tissue development GO:0014706 110 0.639
inner ear morphogenesis GO:0042472 63 0.637
central nervous system neuron axonogenesis GO:0021955 18 0.633
tube morphogenesis GO:0035239 349 0.630
Zebrafish
skeletal muscle tissue development GO:0007519 67 0.630
regulation of smoothened signaling pathway GO:0008589 18 0.629
regulation of multicellular organismal process GO:0051239 277 0.629
regulation of cell differentiation GO:0045595 142 0.628
formation of primary germ layer GO:0001704 62 0.628
organelle organization GO:0006996 227 0.627
Worm
mesodermal cell fate commitment GO:0001710 14 0.622
positive regulation of nervous system development GO:0051962 25 0.620
Mouse
regulation of cardiac muscle tissue development GO:0055024 1 0.620
reproductive process GO:0022414 40 0.614
Mouse Worm Fly
regulation of cell communication GO:0010646 232 0.614
neuron migration GO:0001764 22 0.612
inner ear development GO:0048839 126 0.611
ventral spinal cord interneuron specification GO:0021521 3 0.610
adenohypophysis morphogenesis GO:0048855 4 0.608
rhombomere morphogenesis GO:0021593 17 0.608
skeletal muscle fiber development GO:0048741 35 0.602
negative regulation of rna biosynthetic process GO:1902679 45 0.599
Worm
cellular aromatic compound metabolic process GO:0006725 295 0.595
morphogenesis of embryonic epithelium GO:0016331 30 0.594
limbic system development GO:0021761 16 0.591
negative regulation of cellular biosynthetic process GO:0031327 55 0.584
Worm
central nervous system neuron development GO:0021954 29 0.579
specification of symmetry GO:0009799 204 0.576
multi organism reproductive process GO:0044703 36 0.569
Mouse Worm Fly
positive regulation of muscle tissue development GO:1901863 1 0.565
cell proliferation GO:0008283 80 0.557
Human
positive regulation of fibroblast growth factor receptor signaling pathway GO:0045743 9 0.556
positive regulation of signal transduction GO:0009967 56 0.556
axial mesoderm formation GO:0048320 4 0.554
motor neuron axon guidance GO:0008045 23 0.553
Zebrafish
forebrain neuron differentiation GO:0021879 14 0.552
cellular response to organic cyclic compound GO:0071407 38 0.552
negative regulation of nitrogen compound metabolic process GO:0051172 59 0.551
Worm
death GO:0016265 121 0.545
Worm
myotube differentiation GO:0014902 45 0.543
regulation of transcription from rna polymerase ii promoter GO:0006357 114 0.543
Human Mouse Worm Fly
positive regulation of cell proliferation GO:0008284 15 0.541
Human Mouse
regulation of wnt signaling pathway calcium modulating pathway GO:0008591 3 0.537
regulation of heart growth GO:0060420 2 0.535
periodic partitioning GO:0007365 1 0.535
Fly
regulation of mechanoreceptor differentiation GO:0045631 1 0.533
biological adhesion GO:0022610 40 0.532
multi organism process GO:0051704 134 0.522
Mouse Worm Fly
cell surface receptor signaling pathway involved in heart development GO:0061311 20 0.522
camera type eye morphogenesis GO:0048593 108 0.522
skin development GO:0043588 54 0.519
Human Fly
positive regulation of neural precursor cell proliferation GO:2000179 1 0.515
Mouse
cell migration involved in gastrulation GO:0042074 79 0.514
positive regulation of macromolecule biosynthetic process GO:0010557 59 0.512
Human Mouse Worm Fly
stem cell proliferation GO:0072089 4 0.500
single organism localization GO:1902578 225 0.499
single organism transport GO:0044765 206 0.498
glomerulus development GO:0032835 27 0.494
Zebrafish
hepatic duct development GO:0061011 2 0.492
regulation of neurogenesis GO:0050767 87 0.490
positive regulation of neurogenesis GO:0050769 24 0.490
regulation of stem cell differentiation GO:2000736 4 0.488
cell death GO:0008219 121 0.487
Worm
negative regulation of response to stimulus GO:0048585 104 0.483
Human
organ formation GO:0048645 17 0.473
Fly
somite specification GO:0001757 12 0.460
striated muscle cell development GO:0055002 108 0.456
Zebrafish
positive regulation of signaling GO:0023056 56 0.455
skeletal system development GO:0001501 181 0.455
neuroblast proliferation GO:0007405 2 0.454
establishment of localization in cell GO:0051649 77 0.450
negative regulation of wnt signaling pathway GO:0030178 30 0.448
Human
regulation of bmp signaling pathway GO:0030510 39 0.447
stem cell differentiation GO:0048863 117 0.446
mesodermal cell migration GO:0008078 12 0.443
regulation of cell motility GO:2000145 46 0.443
protein complex subunit organization GO:0071822 46 0.442
Worm
developmental induction GO:0031128 10 0.441
cell migration GO:0016477 237 0.440
Worm
neural retina development GO:0003407 49 0.435
hindbrain morphogenesis GO:0021575 22 0.434
Mouse
negative regulation of metabolic process GO:0009892 86 0.433
Worm
regulation of biological quality GO:0065008 263 0.432
Zebrafish
determination of left right symmetry GO:0007368 179 0.430
dorsal ventral neural tube patterning GO:0021904 1 0.428
developmental growth GO:0048589 166 0.420
embryonic organ morphogenesis GO:0048562 274 0.418
Zebrafish Mouse
positive regulation of cell development GO:0010720 25 0.414
spinal cord dorsal ventral patterning GO:0021513 5 0.412
ventral spinal cord development GO:0021517 35 0.412
astrocyte differentiation GO:0048708 1 0.409
olfactory lobe development GO:0021988 4 0.409
developmental process involved in reproduction GO:0003006 27 0.407
Worm Fly
midbrain hindbrain boundary development GO:0030917 23 0.404
floor plate development GO:0033504 15 0.403
olfactory bulb development GO:0021772 4 0.399
regulation of embryonic development GO:0045995 47 0.398
negative regulation of macromolecule biosynthetic process GO:0010558 48 0.396
Worm
negative regulation of canonical wnt signaling pathway GO:0090090 21 0.393
Human
reproduction GO:0000003 40 0.392
Mouse Worm Fly
establishment of localization GO:0051234 244 0.390
Worm
negative regulation of nervous system development GO:0051961 22 0.389
appendage development GO:0048736 80 0.387
cell cell signaling GO:0007267 52 0.383
Mouse
cardiac atrium morphogenesis GO:0003209 2 0.381
neural precursor cell proliferation GO:0061351 20 0.379
regulation of cell size GO:0008361 29 0.379
cartilage development GO:0051216 96 0.378
positive regulation of stem cell proliferation GO:2000648 1 0.378
cell fate commitment involved in pattern specification GO:0060581 6 0.378
regulation of canonical wnt signaling pathway GO:0060828 34 0.374
Human
negative regulation of transcription dna templated GO:0045892 45 0.373
Worm
regulation of axon extension GO:0030516 24 0.371
segment polarity determination GO:0007367 1 0.370
Fly
liver development GO:0001889 96 0.368
central nervous system development GO:0007417 387 0.367
neuron fate specification GO:0048665 20 0.364
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.360
Human Mouse Worm Fly
negative regulation of smoothened signaling pathway GO:0045879 6 0.358
nephron development GO:0072006 31 0.357
Zebrafish
3 utr mediated mrna stabilization GO:0070935 3 0.356
Zebrafish
specification of organ identity GO:0010092 2 0.354
negative regulation of cell differentiation GO:0045596 46 0.353
regulation of developmental process GO:0050793 247 0.352
developmental cell growth GO:0048588 52 0.350
spinal cord anterior posterior patterning GO:0021512 1 0.350
cell cycle GO:0007049 93 0.345
Worm Fly
optic placode formation involved in camera type eye formation GO:0046619 3 0.344
notochord morphogenesis GO:0048570 17 0.341
Mouse
embryonic eye morphogenesis GO:0048048 30 0.339
positive regulation of response to stimulus GO:0048584 80 0.339
photoreceptor cell differentiation GO:0046530 55 0.337
positive regulation of cell fate specification GO:0042660 1 0.333
protein import into nucleus GO:0006606 3 0.327
morphogenesis of an epithelium GO:0002009 333 0.326
cellular component assembly involved in morphogenesis GO:0010927 107 0.326
regulation of oligodendrocyte differentiation GO:0048713 1 0.323
mesoderm formation GO:0001707 43 0.323
pharyngeal muscle development GO:0043282 4 0.321
endodermal digestive tract morphogenesis GO:0061031 2 0.321
thalamus development GO:0021794 6 0.321
cilium morphogenesis GO:0060271 85 0.320
regulation of locomotion GO:0040012 55 0.320
negative regulation of endodermal cell differentiation GO:1903225 8 0.319
nephron epithelium development GO:0072009 16 0.318
mediolateral intercalation GO:0060031 3 0.318
axon extension GO:0048675 45 0.314
embryonic skeletal system morphogenesis GO:0048704 93 0.312
cardiac cell fate commitment GO:0060911 1 0.311
negative regulation of neuron projection regeneration GO:0070571 4 0.308
regulation of wnt signaling pathway involved in digestive tract morphogenesis GO:2000056 2 0.307
embryonic camera type eye formation GO:0060900 10 0.305
metencephalon development GO:0022037 27 0.304
cell differentiation in spinal cord GO:0021515 40 0.303
regulation of cell death GO:0010941 103 0.300
Worm
embryonic camera type eye morphogenesis GO:0048596 19 0.299
reproductive structure development GO:0048608 5 0.298
Worm
positive regulation of apoptotic process GO:0043065 29 0.298
Worm
morphogenesis of an epithelial fold GO:0060571 1 0.298
myotube cell development GO:0014904 35 0.297
hematopoietic or lymphoid organ development GO:0048534 191 0.296
oocyte maturation GO:0001556 4 0.296
regulation of glial cell differentiation GO:0045685 4 0.292
optic placode formation GO:0001743 4 0.291
positive regulation of cell cycle GO:0045787 3 0.290
Fly
rhombomere boundary formation GO:0021654 10 0.288
cell substrate adhesion GO:0031589 4 0.282
hair cell differentiation GO:0035315 32 0.282
somatic stem cell maintenance GO:0035019 1 0.281
oligodendrocyte differentiation GO:0048709 23 0.279
post embryonic morphogenesis GO:0009886 4 0.279
Zebrafish
positive regulation of programmed cell death GO:0043068 29 0.277
Worm
cardiac endothelial cell differentiation GO:0003348 5 0.267
dorsal ventral axis specification GO:0009950 14 0.266
nuclear transport GO:0051169 4 0.266
regulation of transport GO:0051049 45 0.263
heart morphogenesis GO:0003007 156 0.263
Fly
mesenchyme development GO:0060485 127 0.260
positive regulation of biological process GO:0048518 253 0.253
epithelial to mesenchymal transition GO:0001837 21 0.246
negative regulation of biological process GO:0048519 304 0.244
Human Worm
epithelial cell proliferation involved in liver morphogenesis GO:0072575 2 0.243
regulation of transcription from rna polymerase ii promoter involved in heart development GO:1901213 15 0.241
cellular response to lipid GO:0071396 39 0.241
oogenesis GO:0048477 14 0.233
Fly
endoderm development GO:0007492 49 0.230
regulation of neuron projection development GO:0010975 40 0.230
bmp signaling pathway involved in heart jogging GO:0003303 14 0.229
negative regulation of axon guidance GO:1902668 1 0.228
negative regulation of biosynthetic process GO:0009890 55 0.227
Worm
anterior posterior axon guidance GO:0033564 5 0.227
immune system development GO:0002520 191 0.221
retina development in camera type eye GO:0060041 146 0.221
protein localization to nucleus GO:0034504 3 0.220
multicellular organism growth GO:0035264 4 0.220
heart field specification GO:0003128 1 0.219
negative regulation of gastrulation GO:2000542 11 0.219
hepatocyte proliferation GO:0072574 2 0.219
negative regulation of developmental process GO:0051093 65 0.217
regulation of multicellular organism growth GO:0040014 4 0.215
embryonic pattern specification GO:0009880 44 0.214
Fly
forebrain anterior posterior pattern specification GO:0021797 3 0.214
cell cell signaling involved in cell fate commitment GO:0045168 12 0.214
sensory system development GO:0048880 76 0.213
regulation of cell morphogenesis GO:0022604 42 0.212
positive regulation of embryonic development GO:0040019 3 0.211
hemopoiesis GO:0030097 183 0.210
gliogenesis GO:0042063 45 0.209
regulation of organ morphogenesis GO:2000027 35 0.209
regulation of cell morphogenesis involved in differentiation GO:0010769 38 0.209
endocardial cell differentiation GO:0060956 5 0.209
endocrine pancreas development GO:0031018 27 0.208
Zebrafish
epithelial tube formation GO:0072175 19 0.208
cell proliferation in forebrain GO:0021846 3 0.206
morphogenesis of a branching epithelium GO:0061138 16 0.206
behavior GO:0007610 74 0.204
odontogenesis of dentin containing tooth GO:0042475 1 0.202
negative regulation of endodermal cell fate specification GO:0042664 8 0.202
heart looping GO:0001947 94 0.201
aorta morphogenesis GO:0035909 3 0.199
specification of axis polarity GO:0065001 4 0.197
cellular process involved in reproduction in multicellular organism GO:0022412 28 0.193
Fly
regulation of apoptotic process GO:0042981 98 0.192
Worm
regulation of hormone levels GO:0010817 21 0.190
single organism organelle organization GO:1902589 199 0.188
Worm
peptidyl serine phosphorylation GO:0018105 1 0.187
regulation of meiotic cell cycle GO:0051445 1 0.186
mesenchymal cell proliferation GO:0010463 1 0.186
germ cell development GO:0007281 22 0.184
Fly
tube closure GO:0060606 1 0.181
determination of dorsal ventral asymmetry GO:0048262 34 0.180
regulation of anterior head development GO:2000742 2 0.178
nucleocytoplasmic transport GO:0006913 4 0.178
hypothalamus development GO:0021854 14 0.175
fin development GO:0033333 77 0.174
eye photoreceptor cell differentiation GO:0001754 45 0.174
regulation of synapse organization GO:0050807 3 0.174
regulation of growth GO:0040008 42 0.173
regulation of developmental growth GO:0048638 38 0.173
cell cycle process GO:0022402 53 0.173
Worm Fly
microtubule based process GO:0007017 60 0.172
Worm
regulation of epithelial cell differentiation GO:0030856 7 0.172
Fly
lateral line development GO:0048882 66 0.171
response to external biotic stimulus GO:0043207 97 0.170
embryonic viscerocranium morphogenesis GO:0048703 52 0.167
fin regeneration GO:0031101 51 0.167
kidney epithelium development GO:0072073 23 0.165
ear morphogenesis GO:0042471 64 0.165
anatomical structure homeostasis GO:0060249 36 0.165
negative regulation of cell development GO:0010721 26 0.164
epithelial tube morphogenesis GO:0060562 148 0.163
cardioblast differentiation GO:0010002 9 0.163
retina morphogenesis in camera type eye GO:0060042 79 0.163
embryonic heart tube development GO:0035050 133 0.162
negative regulation of cellular metabolic process GO:0031324 77 0.162
Worm
regulation of endodermal cell differentiation GO:1903224 15 0.162
mechanoreceptor differentiation GO:0042490 37 0.160
limb morphogenesis GO:0035108 7 0.160
muscle cell fate determination GO:0007521 1 0.160
smoothened signaling pathway involved in dorsal ventral neural tube patterning GO:0060831 1 0.159
nephron epithelium morphogenesis GO:0072088 1 0.159
wnt signaling pathway GO:0016055 80 0.158
Human
negative regulation of axon regeneration GO:0048681 4 0.157
bmp signaling pathway involved in determination of left right symmetry GO:0003154 14 0.156
blood vessel development GO:0001568 246 0.155
negative regulation of cell death GO:0060548 60 0.155
formation of anatomical boundary GO:0048859 14 0.154
protein modification process GO:0036211 100 0.154
glandular epithelial cell differentiation GO:0002067 9 0.154
cellular ketone metabolic process GO:0042180 11 0.152
immune system process GO:0002376 241 0.152
convergent extension involved in organogenesis GO:0060029 10 0.151
dendrite morphogenesis GO:0048813 5 0.150
Fly
negative regulation of axon extension GO:0030517 7 0.149
cell fate determination GO:0001709 7 0.148

gli1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
bone development disease DOID:0080006 0 0.463
bone disease DOID:0080001 0 0.463
disease of anatomical entity DOID:7 0 0.463
musculoskeletal system disease DOID:17 0 0.463
connective tissue disease DOID:65 0 0.463
dysostosis DOID:1934 0 0.236